BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0003.p (757 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KA67.1 B3KA67_9BACI DNA topoisomerase EC=5.99.1.2 1147 0.0 B1DJ09.1 B1DJ09_9BACL DNA topoisomerase EC=5.99.1.2 871 0.0 A4INJ7.1 A4INJ7_GEOTN DNA topoisomerase EC=5.99.1.2 775 0.0 B4BJU2.1 B4BJU2_9BACI DNA topoisomerase EC=5.99.1.2 775 0.0 C3IZN4.1 C3IZN4_9BACI DNA topoisomerase III 771 0.0 >B3KA67.1 B3KA67_9BACI DNA topoisomerase EC=5.99.1.2 Length = 712 Score = 1147 bits (2966), Expect = 0.0, Method: Compositional matrix adjust. Identities = 547/711 (76%), Positives = 620/711 (87%), Gaps = 1/711 (0%) Query: 46 MKVLVLAEKPSVAREIARVMGCGNKQKSYIEGPKYVVTWALGHLVGLAEPEDYNNKFANW 105 MKVLVLAEKPSVA+EIARVMG KQK+Y EGPKY+VTWALGHLVGLAEPEDY+ K+ W Sbjct: 1 MKVLVLAEKPSVAKEIARVMGSREKQKNYFEGPKYIVTWALGHLVGLAEPEDYDKKYQTW 60 Query: 106 ALEDLPILPEKAKLKVLRETSQQYKAVQQLMKRQDIEELIVATDAAREGELLARWIMNMA 165 ALEDLPILP+ +LKVL+ETS Q+K VQ LMKR D+ E+I+ATDAAREGELLARWI+ MA Sbjct: 61 ALEDLPILPDNTRLKVLKETSHQFKTVQHLMKRSDVGEMIIATDAAREGELLARWILRMA 120 Query: 166 GWKKPFRRLWISSQTDKAIREGFASLRPGREFDRLYESARCRAEADWMIGLNVTRALTCK 225 W KPF+RLWISSQTDKAI+EGFASL+PG++FDRLYESARCRAEADWM+GLNVTRALT K Sbjct: 121 KWNKPFKRLWISSQTDKAIKEGFASLKPGQQFDRLYESARCRAEADWMVGLNVTRALTTK 180 Query: 226 FGAPLSAGRVQTPTLGMIMDRENEITGFRSQEYDLLTADFGSFQAGWRAQGGDGRIFERD 285 F A LSAGRVQTPTLGMIMDRE EI FRSQEY+ L AD GSF+ WR GGDGR+FE+D Sbjct: 181 FNAQLSAGRVQTPTLGMIMDREREIVNFRSQEYETLQADLGSFEVSWRPAGGDGRLFEKD 240 Query: 286 TTAKLKEKLTGRSGRIAKVQKSEKSEPHPLAYDLTELQRDANRKFGFSAKQTSSVLQRLY 345 AKLK+KL G +G+I V+KSEK+EPHPLAYDLTELQRDANR+FGFSAKQTS+VLQRLY Sbjct: 241 KAAKLKQKLEGSTGKIVSVKKSEKTEPHPLAYDLTELQRDANRRFGFSAKQTSNVLQRLY 300 Query: 346 EQHKLVTYPRTDSRYLTSDMTGTLKERLDSVAVGXXXXXXXXXXXXXXXITKRVVDDSKV 405 EQHKLVTYPRTDSRYLTSDM GTLKERL S+A+G KRVVDDSKV Sbjct: 301 EQHKLVTYPRTDSRYLTSDMVGTLKERLSSIAIGPYASIARPLLRKNLSPGKRVVDDSKV 360 Query: 406 SDHHAIIPTEQTVLLNQLSAEERKLYDLIVRRFISLFYPAARYDAVAVTVNVDGEVFHVK 465 +DHHAIIPTEQTVLLNQLS +ERKLYDLIVRRFISLFYP ARYD V+VTV ++GE + K Sbjct: 361 TDHHAIIPTEQTVLLNQLSVDERKLYDLIVRRFISLFYPPARYDNVSVTVQIEGEQLYAK 420 Query: 466 GTTVKDGGWREVYGGDMSSDDEDENTADE-PAAGSVKLPELREGEAVTVQRCIIRPGRTQ 524 GTT+KD GWREVYGGD D +DE+ + P++ LPEL+EGE+V V RC+++PGRTQ Sbjct: 421 GTTIKDSGWREVYGGDYEDDTDDESDDGQGPSSSGKLLPELKEGESVKVVRCVLKPGRTQ 480 Query: 525 PPKRYNEASLLTQMEKHGLGTPATRADIIEKLVSSDTIERQGNLLHPTGKGKQLIGLVAG 584 PPKRYNEA+LL+QMEKHGLGTPATRADIIEKLVSSDTIERQG LHPTGKGKQLI LVA Sbjct: 481 PPKRYNEAALLSQMEKHGLGTPATRADIIEKLVSSDTIERQGQTLHPTGKGKQLIELVAP 540 Query: 585 QLRTPELTARWEAELEKIARGQGRPEPFLQGIRSMAQELVSGVKNSGAEYKPHNVSNSHC 644 +LRTPELTARWEAELE+IA+GQG+PEPFL+GIR M ++LV+ VK S AEYKPHNVSNSHC Sbjct: 541 ELRTPELTARWEAELERIAKGQGKPEPFLRGIRDMTKKLVTDVKGSEAEYKPHNVSNSHC 600 Query: 645 PNCGTRLLEKKTKRGKLLVCPADDCGYTRAGEKQLSNRRCPQCHKKMELKEGKAGLYVQC 704 P+CGTRLLEKKTKRGKLLVCP+DDCGY R+GEK+LSNRRCPQCHKKME+KEGKAGL+VQC Sbjct: 601 PDCGTRLLEKKTKRGKLLVCPSDDCGYKRSGEKRLSNRRCPQCHKKMEMKEGKAGLFVQC 660 Query: 705 LGCGITETMDKDHKHINKREQQRLVQQYSKQESVGSNLGELLKAAMEAKEK 755 LGCGITET+ KD KH+NKRE+++LVQQYSKQES+GSNLG+LLKAA+E K K Sbjct: 661 LGCGITETLKKDAKHVNKREERKLVQQYSKQESIGSNLGDLLKAALEQKGK 711 >B1DJ09.1 B1DJ09_9BACL DNA topoisomerase EC=5.99.1.2 Length = 719 Score = 871 bits (2250), Expect = 0.0, Method: Compositional matrix adjust. Identities = 427/717 (59%), Positives = 533/717 (74%), Gaps = 8/717 (1%) Query: 46 MKVLVLAEKPSVAREIARVMGCGNKQKSYIEGPKYVVTWALGHLVGLAEPEDYNNKFANW 105 MK LVLAEKPSVA+EIARV+GC +K KSY+EGP YVVTWALGHLV LAEPEDY+ K+ W Sbjct: 1 MKSLVLAEKPSVAKEIARVLGCSSKNKSYMEGPDYVVTWALGHLVTLAEPEDYDPKYKTW 60 Query: 106 ALEDLPILPEKAKLKVLRETSQQYKAVQQLMKRQDIEELIVATDAAREGELLARWIMNMA 165 LEDLP+LP K LKV+RETS QYKAV QL KR DI ELI+ATDA REGEL+ARWIM + Sbjct: 61 NLEDLPLLPGKMNLKVMRETSHQYKAVAQLCKRPDIGELIIATDAGREGELVARWIMELV 120 Query: 166 GWKKPFRRLWISSQTDKAIREGFASLRPGREFDRLYESARCRAEADWMIGLNVTRALTCK 225 W+KPF+RLWISSQTDKAI++GF +L+PG++++ LY SA CRAEADW+IGLNVTRALT K Sbjct: 121 HWRKPFKRLWISSQTDKAIKDGFKALKPGQQYNNLYASAVCRAEADWLIGLNVTRALTVK 180 Query: 226 FGAPLSAGRVQTPTLGMIMDRENEITGFRSQEYDLLTADFGSFQAGWRAQGG-DGRIFER 284 + A L+AGRVQTPTLG ++DRE EI F+SQ Y ++A+ G+FQA WR DGR+++R Sbjct: 181 YNAQLAAGRVQTPTLGALIDREKEINQFQSQPYWTVSAELGAFQALWRQNDNHDGRVWDR 240 Query: 285 DTTAKLKEKLTGRSGRIAKVQKSEKSEPHPLAYDLTELQRDANRKFGFSAKQTSSVLQRL 344 + +L G+S ++ K++ ++KSEPHP A+DLTELQR+AN++ GFSAK TS+VLQ+L Sbjct: 241 SEAEAVIARLQGKSAKVDKLRTTQKSEPHPQAFDLTELQREANKRLGFSAKMTSNVLQKL 300 Query: 345 YEQHKLVTYPRTDSRYLTSDMTGTLKERLDSVAVGXXXXXXXXXXXXXXXITKRVVDDSK 404 YEQHKLVTYPRTDSRYL+SD+ TLK RL+SVAVG +TKR VDDSK Sbjct: 301 YEQHKLVTYPRTDSRYLSSDIVPTLKGRLESVAVGPYAPLARKLLRGQLTVTKRFVDDSK 360 Query: 405 VSDHHAIIPTEQTVLLNQLSAEERKLYDLIVRRFISLFYPAARYDAVAVTVNVDGEVFHV 464 VSDHHAIIPT++ V L+ LS +ERKLYDLIVRRFI+LFYP YD +V + V + + Sbjct: 361 VSDHHAIIPTDEYVNLSALSNDERKLYDLIVRRFIALFYPPYTYDETSVVLTVGQDKLYA 420 Query: 465 KGTTVKDGGWREVYGGD-----MSSDDEDENTADEPAAGSVK-LPELREGEAVTVQRCII 518 KG KD GW+E+YGG DDE+EN E + + LPEL +G+AV V++ + Sbjct: 421 KGKVQKDIGWKELYGGSDARFTADEDDEEENGRGEDKSTPEQLLPELVQGQAVQVKQSRL 480 Query: 519 RPGRTQPPKRYNEASLLTQMEKHGLGTPATRADIIEKLVSSDTIERQGNLLHPTGKGKQL 578 + RT PP RY EASLL++MEKHGLGTPATRADIIEKL+S+DTIER N L PT KGKQL Sbjct: 481 KELRTLPPARYTEASLLSKMEKHGLGTPATRADIIEKLLSTDTIERTQNRLVPTSKGKQL 540 Query: 579 IGLVAGQLRTPELTARWEAELEKIARGQGRPEPFLQGIRSMAQELVSGVKNSGAEYKPHN 638 I LV +LR+PELTA+WE ELE IA GQG + F+ GIR A + V+ VKN EYKPHN Sbjct: 541 IELVVDELRSPELTAKWERELELIAHGQGDAKRFMAGIREQANKWVTAVKNETKEYKPHN 600 Query: 639 VSNSHCPNCGTRLLEKKTKRGKLLVCPADDCGYTRAGEKQLSNRRCPQCHKKMELKEGKA 698 +++S CP CG L+E K KRGK LVC +C Y R E LSN+RCPQCHKKME+ GKA Sbjct: 601 LTHSRCPECGKLLMEVKGKRGKSLVCSDRECSYRRQAEPALSNKRCPQCHKKMEIHNGKA 660 Query: 699 GLYVQCLGCGITETM-DKDHKHINKREQQRLVQQYSKQESVGSNLGELLKAAMEAKE 754 G Y QC C + E + DK +NK +Q+++++QYS S+ ++L + LKAAM ++ Sbjct: 661 GKYAQCRPCNVIEMLGDKQGGRVNKHQQKKMIEQYSDNVSLSNSLADALKAAMNKQD 717 >A4INJ7.1 A4INJ7_GEOTN DNA topoisomerase EC=5.99.1.2 Length = 696 Score = 775 bits (2002), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/710 (53%), Positives = 494/710 (69%), Gaps = 15/710 (2%) Query: 46 MKVLVLAEKPSVAREIARVMGCGNKQKSYIEGPKYVVTWALGHLVGLAEPEDYNNKFANW 105 MK LVLAEKPSVAR+IARV+GC KSY+EGP+Y+VTWALGHLV L PEDY+ K+ W Sbjct: 1 MKSLVLAEKPSVARDIARVLGCKKTHKSYLEGPRYIVTWALGHLVELKMPEDYDRKYETW 60 Query: 106 ALEDLPILPEKAKLKVLRETSQQYKAVQQLMKRQDIEELIVATDAAREGELLARWIMNMA 165 LEDLPI+P+K LKV+R+TS Q++A+++L KR+D+++ I+ATDA REGEL+ARWI+ Sbjct: 61 RLEDLPIIPKKMGLKVIRQTSHQFRAIERLAKRRDVKDCIIATDAGREGELVARWILQKI 120 Query: 166 GWKKPFRRLWISSQTDKAIREGFASLRPGREFDRLYESARCRAEADWMIGLNVTRALTCK 225 WKKP RLWISSQTD+AIR+GF L+PG +FDRLYESA CRAEADW+IGLNVTRALT K Sbjct: 121 DWKKPIWRLWISSQTDQAIRDGFRQLKPGTQFDRLYESAICRAEADWLIGLNVTRALTTK 180 Query: 226 FGAPLSAGRVQTPTLGMIMDRENEITGFRSQEYDLLTADFGSFQAGWRAQGGDGRIFERD 285 + PLSAGRVQTPTL MI++RE EI F Y + A GS A W GG R+F++D Sbjct: 181 YNDPLSAGRVQTPTLAMIIEREREIQSFVPVPYWTIHARIGSVTAVWERHGGK-RLFDKD 239 Query: 286 TTAKLKEKLTGRSGRIAKVQKSEKSEPHPLAYDLTELQRDANRKFGFSAKQTSSVLQRLY 345 +L +L G+ R+ V++ KSEP PL YDLTELQR+AN++FGFSAK+T SVLQRLY Sbjct: 240 EANELMTRLKGQPARVTSVKRKRKSEPVPLPYDLTELQREANKRFGFSAKKTLSVLQRLY 299 Query: 346 EQHKLVTYPRTDSRYLTSDMTGTLKERLDSVAVGXXXXXXXXXXXXXXXITKRVVDDSKV 405 EQHKLVTYPRTDSRYL SDM T+ +RL ++ G RV D KV Sbjct: 300 EQHKLVTYPRTDSRYLPSDMKATMTDRLLAMKPGYEDVISSLLTKKNVKAANRVFQDDKV 359 Query: 406 SDHHAIIPTEQTVLLNQLSAEERKLYDLIVRRFISLFYPAARYDAVAVTVNVDGEVFHVK 465 +DHHAIIPT++ + L +LS +ERKLYD+I RRF++LFYP Y+ V + E F + Sbjct: 360 TDHHAIIPTDERLDLAKLSVDERKLYDMIARRFLALFYPPYEYETATVVFEIGDETFVAR 419 Query: 466 GTTVKDGGWREVYGGDMSSDDEDENTADEPAAGSVKLPELREGEAVTVQRCIIRPGRTQP 525 T V + G++ V G E T +P L L EG+ + + + T+P Sbjct: 420 ETAVVNAGFKAVLG--------KEETEAKPT-----LLHLSEGQTLASVQLEMEQSFTEP 466 Query: 526 PKRYNEASLLTQMEKHGLGTPATRADIIEKLVSSDTIERQGNLLHPTGKGKQLIGLVAGQ 585 P RY+EA LL QME++GLGTPATRADIIE+LV ++ +ER+ +PT KGKQLI LV + Sbjct: 467 PSRYSEADLLAQMERYGLGTPATRADIIERLVETEVVERKDGRFYPTKKGKQLIELVNEE 526 Query: 586 LRTPELTARWEAELEKIARGQGRPEPFLQGIRSMAQELVSGVKNSGAEYKPHNVSNSHCP 645 L++PELTARWE ELE IARG+G P+ FL IR ++LV+ +K S YK N++N CP Sbjct: 527 LKSPELTARWERELEAIARGKGNPKQFLANIRRQTEQLVTEIKQSEQTYKAPNLTNLTCP 586 Query: 646 NCGTRLLEKKTKRGKLLVCPADDCGYTRAGEKQLSNRRCPQCHKKMELKEGKAGLYVQCL 705 CG+ L E+KTK G++LVC +C Y R + +LSNRRCPQCH++ME+ EGKAGLY QC Sbjct: 587 ECGSLLKERKTKDGRMLVCSNLECRYRRRRDPKLSNRRCPQCHRRMEMHEGKAGLYFQCR 646 Query: 706 GCGITETMDKDHKHINKREQQRLVQQYS-KQESVGSNLGELLKAAMEAKE 754 C I E ++ + K ++ L+++YS ES G++LGELLK A+E KE Sbjct: 647 PCNIVEKAEETKRTSAKGTERALLKKYSPSNESFGTSLGELLKQALEKKE 696 >B4BJU2.1 B4BJU2_9BACI DNA topoisomerase EC=5.99.1.2 Length = 696 Score = 775 bits (2002), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/710 (53%), Positives = 494/710 (69%), Gaps = 15/710 (2%) Query: 46 MKVLVLAEKPSVAREIARVMGCGNKQKSYIEGPKYVVTWALGHLVGLAEPEDYNNKFANW 105 MK LVLAEKPSVAR+IARV+GC KSY+EGP+Y+VTWALGHLV L PEDY+ K+ W Sbjct: 1 MKSLVLAEKPSVARDIARVLGCKKTHKSYLEGPRYIVTWALGHLVELKMPEDYDRKYETW 60 Query: 106 ALEDLPILPEKAKLKVLRETSQQYKAVQQLMKRQDIEELIVATDAAREGELLARWIMNMA 165 LEDLPI+P+K LKV+R+TS Q++A+++L KR+D+++ I+ATDA REGEL+ARWI+ Sbjct: 61 RLEDLPIIPKKMGLKVIRQTSHQFRAIERLAKRRDVKDCIIATDAGREGELVARWILQKI 120 Query: 166 GWKKPFRRLWISSQTDKAIREGFASLRPGREFDRLYESARCRAEADWMIGLNVTRALTCK 225 WKKP RLWISSQTD+AIR+GF L+PG +FDRLYESA CRAEADW+IGLNVTRALT K Sbjct: 121 DWKKPIWRLWISSQTDQAIRDGFRQLKPGTQFDRLYESAICRAEADWLIGLNVTRALTTK 180 Query: 226 FGAPLSAGRVQTPTLGMIMDRENEITGFRSQEYDLLTADFGSFQAGWRAQGGDGRIFERD 285 + PLSAGRVQTPTL MI++RE EI F Y + A GS A W GG R+F++D Sbjct: 181 YNDPLSAGRVQTPTLAMIIEREREIQSFVPVPYWTIHARIGSVTAVWERHGGK-RLFDKD 239 Query: 286 TTAKLKEKLTGRSGRIAKVQKSEKSEPHPLAYDLTELQRDANRKFGFSAKQTSSVLQRLY 345 +L +L G+ R+ V++ KSEP PL YDLTELQR+AN++FGFSAK+T SVLQRLY Sbjct: 240 EANELMTRLKGQPARVTSVKRKRKSEPVPLPYDLTELQREANKRFGFSAKKTLSVLQRLY 299 Query: 346 EQHKLVTYPRTDSRYLTSDMTGTLKERLDSVAVGXXXXXXXXXXXXXXXITKRVVDDSKV 405 EQHKLVTYPRTDSRYL SDM T+ +RL ++ G RV D KV Sbjct: 300 EQHKLVTYPRTDSRYLPSDMKATMTDRLLAMKPGYEDVISSLLTKKNVKAANRVFQDDKV 359 Query: 406 SDHHAIIPTEQTVLLNQLSAEERKLYDLIVRRFISLFYPAARYDAVAVTVNVDGEVFHVK 465 +DHHAIIPT++ + L +LS +ERKLYD+I RRF++LFYP Y+ V + E F + Sbjct: 360 TDHHAIIPTDERLDLAKLSVDERKLYDMIARRFLALFYPPYEYETATVVFEIGDETFVAR 419 Query: 466 GTTVKDGGWREVYGGDMSSDDEDENTADEPAAGSVKLPELREGEAVTVQRCIIRPGRTQP 525 T V + G++ V G E T +P L L EG+ + + + T+P Sbjct: 420 ETAVVNAGFKAVLG--------KEETEAKPT-----LLHLSEGQTLASVQLEMEQSFTEP 466 Query: 526 PKRYNEASLLTQMEKHGLGTPATRADIIEKLVSSDTIERQGNLLHPTGKGKQLIGLVAGQ 585 P RY+EA LL QME++GLGTPATRADIIE+LV ++ +ER+ +PT KGKQLI LV + Sbjct: 467 PSRYSEADLLAQMERYGLGTPATRADIIERLVETEVVERKDGRFYPTKKGKQLIELVNEE 526 Query: 586 LRTPELTARWEAELEKIARGQGRPEPFLQGIRSMAQELVSGVKNSGAEYKPHNVSNSHCP 645 L++PELTARWE ELE IARG+G P+ FL IR ++LV+ +K S YK N++N CP Sbjct: 527 LKSPELTARWERELEAIARGKGNPKQFLANIRRQTEQLVTEIKQSEQTYKAPNLTNLTCP 586 Query: 646 NCGTRLLEKKTKRGKLLVCPADDCGYTRAGEKQLSNRRCPQCHKKMELKEGKAGLYVQCL 705 CG+ L E+KTK G++LVC +C Y R + +LSNRRCPQCH++ME+ EGKAGLY QC Sbjct: 587 ECGSLLKERKTKDGRMLVCSNLECRYRRRRDPKLSNRRCPQCHRRMEMHEGKAGLYFQCR 646 Query: 706 GCGITETMDKDHKHINKREQQRLVQQYS-KQESVGSNLGELLKAAMEAKE 754 C I E ++ + K ++ L+++YS ES G++LGELLK A+E KE Sbjct: 647 PCNIVEKAEETKRTSAKGTERALLKKYSPSNESFGTSLGELLKQALEKKE 696 >C3IZN4.1 C3IZN4_9BACI DNA topoisomerase III Length = 697 Score = 771 bits (1990), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/711 (53%), Positives = 494/711 (69%), Gaps = 15/711 (2%) Query: 46 MKVLVLAEKPSVAREIARVMGCGNKQKSYIEGPKYVVTWALGHLVGLAEPEDYNNKFANW 105 MK LVLAEKPSVAR+IARV+GC K Y EGP+Y+VTWALGHLV L PEDY+ K+ W Sbjct: 1 MKSLVLAEKPSVARDIARVLGCKETHKPYFEGPRYIVTWALGHLVELKMPEDYDRKYETW 60 Query: 106 ALEDLPILPEKAKLKVLRETSQQYKAVQQLMKRQDIEELIVATDAAREGELLARWIMNMA 165 LEDLPI+P+K LKV+R+TS Q++A+++L KR D++++I+ATDA REGEL+ARWI+ M Sbjct: 61 RLEDLPIIPKKMGLKVIRQTSHQFRAIERLAKRPDVKDVIIATDAGREGELVARWILEMI 120 Query: 166 GWKKPFRRLWISSQTDKAIREGFASLRPGREFDRLYESARCRAEADWMIGLNVTRALTCK 225 GW KP RLWISSQTD+AIR+GF L+PG +FDRLY+SA CRAEADW+IGLNV+RALT K Sbjct: 121 GWTKPIWRLWISSQTDRAIRDGFRQLKPGAQFDRLYQSAVCRAEADWLIGLNVSRALTTK 180 Query: 226 FGAPLSAGRVQTPTLGMIMDRENEITGFRSQEYDLLTADFGSFQAGWRAQGGDGRIFERD 285 + PLSAGRVQTPTL MI++RE EI F Y + A GS A W GG R+F++D Sbjct: 181 YNDPLSAGRVQTPTLAMIIEREREIQSFVPVPYWTIRAKIGSITAVWERHGGH-RLFDQD 239 Query: 286 TTAKLKEKLTGRSGRIAKVQKSEKSEPHPLAYDLTELQRDANRKFGFSAKQTSSVLQRLY 345 +L +L G+ R+ V++ KSEP PL YDLTELQRDAN++FGFSAK+T SVLQRLY Sbjct: 240 EAKQLLARLDGQPARVVSVKRKRKSEPAPLPYDLTELQRDANKRFGFSAKKTLSVLQRLY 299 Query: 346 EQHKLVTYPRTDSRYLTSDMTGTLKERLDSVAVGXXXXXXXXXXXXXXXITKRVVDDSKV 405 EQHKLVTYPRTDSRYL SDM T+ ERL ++ G KRV +D KV Sbjct: 300 EQHKLVTYPRTDSRYLPSDMEATMTERLLAMKSGYEDVIAPLLAKGKAKAAKRVFNDDKV 359 Query: 406 SDHHAIIPTEQTVLLNQLSAEERKLYDLIVRRFISLFYPAARYDAVAVTVNVDGEVFHVK 465 +DHHAI+PT++ + L++LS +ERKLYDLI RRF++LF+P + ++ GE+F K Sbjct: 360 TDHHAIVPTDERLNLSRLSTDERKLYDLIARRFLALFFPPYESETTTAVFDIGGEMFVAK 419 Query: 466 GTTVKDGGWREVYGGDMSSDDEDENTADEPAAGSVKLPELREGEAVTVQRCIIRPGRTQP 525 T V + G++ V G E T +P L L EG+ + + T+P Sbjct: 420 ETAVVNFGFKAVLG--------KEETDAKPT-----LSHLAEGQTLPSVQLEREQSFTEP 466 Query: 526 PKRYNEASLLTQMEKHGLGTPATRADIIEKLVSSDTIERQGNLLHPTGKGKQLIGLVAGQ 585 P RY+EA LL QMEK+GLGTPATRADIIE+LV ++ +ER+ +PT KGKQLI LV + Sbjct: 467 PARYSEADLLAQMEKYGLGTPATRADIIERLVETEVVERKDGRFYPTKKGKQLIELVNEE 526 Query: 586 LRTPELTARWEAELEKIARGQGRPEPFLQGIRSMAQELVSGVKNSGAEYKPHNVSNSHCP 645 L++PELTARWE ELE IARG+G P+ FL IR Q+LV+ +K S YK N++N CP Sbjct: 527 LKSPELTARWERELEAIARGKGNPQQFLANIRRQTQQLVAEIKQSEQVYKAPNLTNLTCP 586 Query: 646 NCGTRLLEKKTKRGKLLVCPADDCGYTRAGEKQLSNRRCPQCHKKMELKEGKAGLYVQCL 705 CG L E+KTK G++LVC C Y R + +LSNRRCPQCH++ME+ EGKAG+Y QC Sbjct: 587 ECGALLKERKTKDGRMLVCSNLACRYRRRRDPKLSNRRCPQCHRRMEMHEGKAGMYFQCR 646 Query: 706 GCGITETMDKDHKHINKREQQRLVQQYSK-QESVGSNLGELLKAAMEAKEK 755 C I E D+ + K ++ L+++YS ES G++LGELLK A+ K++ Sbjct: 647 PCNIVEKADETKRIAAKGSERALLKKYSPANESFGTSLGELLKQALNEKKE 697 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.316 0.133 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 4,371,486,473 Number of extensions: 184233574 Number of successful extensions: 489403 Number of sequences better than 1.0e-05: 3277 Number of HSP's gapped: 472767 Number of HSP's successfully gapped: 3722 Length of query: 757 Length of database: 3,060,696,203 Length adjustment: 144 Effective length of query: 613 Effective length of database: 1,704,070,043 Effective search space: 1044594936359 Effective search space used: 1044594936359 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 135 (56.6 bits)