BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0011.p (407 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K343.1 B3K343_9BACI Histidine--tRNA ligase EC=6.1.1.21 513 e-143 B1DKW9.1 B1DKW9_9BACL Histidine--tRNA ligase EC=6.1.1.21 477 e-133 C0Z6Q0.1 C0Z6Q0_BREBN ATP phosphoribosyltransferase regulatory s... 323 2e-86 Q9K6Z0.1 HISZ_BACHD ATP phosphoribosyltransferase regulatory sub... 286 3e-75 Q2B726.1 Q2B726_9BACI ATP phosphoribosyltransferase regulatory s... 285 4e-75 >B3K343.1 B3K343_9BACI Histidine--tRNA ligase EC=6.1.1.21 Length = 397 Score = 513 bits (1322), Expect = e-143, Method: Compositional matrix adjust. Identities = 248/374 (66%), Positives = 295/374 (78%) Query: 3 MSKPKGFEKPAGVRDYLPRAVTKLRKIEKDVLHCMSRWGYRQMITPTLEYYDTVGVASST 62 MSKPKGFEKPAGVRDYLP AVTKLR+IE++VL CM RWGYRQ++TPT+EYYDTVGVASST Sbjct: 1 MSKPKGFEKPAGVRDYLPHAVTKLRRIEREVLACMDRWGYRQIMTPTMEYYDTVGVASST 60 Query: 63 SDQKLYKLLNNRGQALVLRSEMTAPVARVVSSLLKDEPLPLRLSYHANVXXXXXXXXXXX 122 SDQKL+KLLN RG +VLRS++TAP+ARV+SSLLKDEPLP+RLSYHANV Sbjct: 61 SDQKLFKLLNKRGTTMVLRSDLTAPIARVMSSLLKDEPLPVRLSYHANVFRAIEEEAGRE 120 Query: 123 XXXXQTGVELVGDDSPEADAEVVALAISSLQAAGVKSFKIAMGHVGFLDGLFQEAVAGLP 182 QTGVELVGDD+PEADAEV+ALAI SL+AAGV+ FKIAMGH+G+L+GL QE + Sbjct: 121 AEFFQTGVELVGDDTPEADAEVIALAIESLKAAGVEKFKIAMGHMGYLNGLLQEVLPDRT 180 Query: 183 DAQEELKSHLLNRDYVAFRETLRRLELSEAQKNELDGLLRLRGGKEICGQALELSSHPLA 242 + QE LK LLNRDYV +R T+ L L+E Q+++L+G+L+LRGG+EI GQALE+SS+ LA Sbjct: 181 EDQESLKQDLLNRDYVGYRNTIASLSLTEVQQDQLEGILKLRGGREIAGQALEISSNELA 240 Query: 243 RASIEHLCKVWEVLVSYGVSQHVLIDLTMIGDFSYYTGMTFEGYASELGFPVCSGGRYDN 302 RASIEHL KVWEVL +Y VS+HVL DLTM+GDFSYYTGMTFEGYA+ELG PV SGGRYD Sbjct: 241 RASIEHLSKVWEVLEAYDVSRHVLFDLTMLGDFSYYTGMTFEGYAAELGSPVASGGRYDK 300 Query: 303 LLQQFGRPVPSTGFSLKTNRILDGVSGVPEEEELPILIQYDAPXXXXXXXXXXXXXXXXH 362 LL+QFGR VP+TGF+LKTNRILDGV G EELPILI+Y A H Sbjct: 301 LLRQFGRAVPATGFALKTNRILDGVQGEEIVEELPILIRYTASHRKEGLAKASELRAQGH 360 Query: 363 VVVTRLAAEPGDLK 376 V+T + + + + Sbjct: 361 SVITSIIPDSANAR 374 >B1DKW9.1 B1DKW9_9BACL Histidine--tRNA ligase EC=6.1.1.21 Length = 407 Score = 477 bits (1227), Expect = e-133, Method: Compositional matrix adjust. Identities = 237/344 (68%), Positives = 275/344 (79%), Gaps = 3/344 (0%) Query: 3 MSKPKGFEKPAGVRDYLPRAVTKLRKIEKDVLHCMSRWGYRQMITPTLEYYDTVGVASST 62 MSKPK FEKP GV+DYLP AV KLR IE+DVL CM WGY Q+ITPT+EYYDTVGVASST Sbjct: 1 MSKPKVFEKPIGVKDYLPGAVAKLRHIERDVLACMKGWGYEQIITPTMEYYDTVGVASST 60 Query: 63 SDQKLYKLLNNRGQALVLRSEMTAPVARVVSSLLKDEPLPLRLSYHANVXXXXXXXXXXX 122 SDQKL+KLLNNRG LVLRS+MTAP+ARVVSSLLK+ PLRLSYH NV Sbjct: 61 SDQKLFKLLNNRGTTLVLRSDMTAPIARVVSSLLKESQFPLRLSYHGNVFRSIEEESGRE 120 Query: 123 XXXXQTGVELVGDDSPEADAEVVALAISSLQAAGVKSFKIAMGHVGFLDGLFQEAVAGLP 182 QTGVELVGD S EADAEVVALAI+SL+AAGV FKIA+GHVGFL+GLF+E +AG Sbjct: 121 AEFFQTGVELVGDASAEADAEVVALAIASLKAAGVDRFKIAIGHVGFLNGLFEETLAGRV 180 Query: 183 DAQEELKSHLLNRDYVAFRETLRRLELSEAQKNELDGLLRLRGGKEICGQALELSSHPLA 242 +AQE+LKS LLNRDYV +RE+LR L+L E + EL+G+LRLRGG+EIC QAL+LS+ A Sbjct: 181 EAQEQLKSCLLNRDYVGYRESLRGLKLEEPVQRELEGILRLRGGQEICEQALQLSADATA 240 Query: 243 RASIEHLCKVWEVLVSYGVSQHVLIDLTMIGDFSYYTGMTFEGYASELGFPVCSGGRYDN 302 + SI HLC++W+VL +Y V +HVLIDLTMIGDFSYYTGMTFEGYA++LGFPV SGGRYDN Sbjct: 241 QKSIRHLCEIWDVLKAYDVCEHVLIDLTMIGDFSYYTGMTFEGYAADLGFPVASGGRYDN 300 Query: 303 LLQQFGRPVPSTGFSLKTNRILDGVSGVPEEE--ELPILIQYDA 344 LL QFGRP P+TGF+LKT RIL+ V G E+ +LI YD Sbjct: 301 LLSQFGRPAPATGFALKTTRILELV-GAEEDATGTTRVLIGYDG 343 >C0Z6Q0.1 C0Z6Q0_BREBN ATP phosphoribosyltransferase regulatory subunit Length = 391 Score = 323 bits (828), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 159/369 (43%), Positives = 235/369 (63%), Gaps = 1/369 (0%) Query: 3 MSKPKGFEKPAGVRDYLPRAVTKLRKIEKDVLHCMSRWGYRQMITPTLEYYDTVGVASST 62 M+KP GFEKP G+RD LP ++ K R +E+++ C+ RWGY ++ TP+LEY+DTVG AS+T Sbjct: 1 MAKPLGFEKPLGMRDILPESLAKQRHLERELRQCIERWGYDEISTPSLEYFDTVGAASAT 60 Query: 63 SDQKLYKLLNNRGQALVLRSEMTAPVARVVSSLLKDEPLPLRLSYHANVXXXXXXXXXXX 122 ++++LL+ +G +VLR +MT P+ARVVSSL KD PLP+RL Y NV Sbjct: 61 LTDRMFRLLDKQGHTVVLRPDMTTPIARVVSSLYKDVPLPIRLYYQVNVFRAQEKEAGRN 120 Query: 123 XXXXQTGVELVGDDSPEADAEVVALAISSLQAAGVKSFKIAMGHVGFLDGLFQEAVAGLP 182 QTG+EL+GD S +ADAE +ALA+ L+AAGV++F+IA+GHV F+DGL +E + P Sbjct: 121 AEFSQTGIELIGDASVDADAEAIALAVVCLRAAGVETFRIAIGHVDFVDGLLEEEIEDEP 180 Query: 183 DAQEELKSHLLNRDYVAFRETLRRLELSEAQKNELDGLLRLRGGKEICGQALELSSHPLA 242 + + + L RD+V FR+ L +++S + L+ LLRL+GGK A +L+ + A Sbjct: 181 -IRNQFRQFLYERDFVGFRQLLATVDISTEANSRLEALLRLQGGKGKIEVARKLAGNGKA 239 Query: 243 RASIEHLCKVWEVLVSYGVSQHVLIDLTMIGDFSYYTGMTFEGYASELGFPVCSGGRYDN 302 ++E + +WE L +YGV++ +LID +I + +YYTG+ FEGYA++LG P+ GGRYD Sbjct: 240 GRAVETIASLWESLEAYGVTEDLLIDFNLIINLNYYTGVVFEGYAADLGSPLLGGGRYDQ 299 Query: 303 LLQQFGRPVPSTGFSLKTNRILDGVSGVPEEEELPILIQYDAPXXXXXXXXXXXXXXXXH 362 LL QFGR +TGF++K +R+L V + +L+ Y Sbjct: 300 LLSQFGRAASATGFAIKMDRLLQVTPSVKRQAPARVLLVYTEDCRGTALAEAQLLRKDGL 359 Query: 363 VVVTRLAAE 371 VVVTRL ++ Sbjct: 360 VVVTRLVSK 368 >Q9K6Z0.1 HISZ_BACHD ATP phosphoribosyltransferase regulatory subunit Length = 397 Score = 286 bits (732), Expect = 3e-75, Method: Compositional matrix adjust. Identities = 144/327 (44%), Positives = 208/327 (63%), Gaps = 1/327 (0%) Query: 3 MSKPKGFEKPAGVRDYLPRAVTKLRKIEKDVLHCMSRWGYRQMITPTLEYYDTVGVASST 62 MSKP FEKP G+RD LP + I + ++ WGY + TPTLEYY+TVGV S+ Sbjct: 1 MSKPFMFEKPFGMRDTLPEWYKTKKNICDQMTEEINLWGYDMIETPTLEYYETVGVVSAI 60 Query: 63 SDQKLYKLLNNRGQALVLRSEMTAPVARVVSSLLKDEPLPLRLSYHANVXXXXXXXXXXX 122 DQ+L+KLL+ +G LVLR +MTAP+AR+V+S LKD PLRL+Y +NV Sbjct: 61 LDQQLFKLLDQQGNTLVLRPDMTAPIARLVASSLKDRAYPLRLAYQSNVYRAQQNEGGKP 120 Query: 123 XXXXQTGVELVGDDSPEADAEVVALAISSLQAAGVKSFKIAMGHVGFLDGLFQEAVAGLP 182 Q GVEL+GD + AD EV+AL I++L+ AG+ FK+A+GHVG+++ L + V G Sbjct: 121 AEFEQLGVELIGDGTASADGEVIALMIAALKRAGLSEFKVAIGHVGYVNALLMD-VVGNE 179 Query: 183 DAQEELKSHLLNRDYVAFRETLRRLELSEAQKNELDGLLRLRGGKEICGQALELSSHPLA 242 + L+ L ++YV +RE ++ L LS K+ L LL LRGG+ +A L Sbjct: 180 QRADRLRRFLYEKNYVGYREHVKSLNLSTIDKSRLMNLLSLRGGRAAIEEARGLIQTEKG 239 Query: 243 RASIEHLCKVWEVLVSYGVSQHVLIDLTMIGDFSYYTGMTFEGYASELGFPVCSGGRYDN 302 + ++ + K++EVL SYG S++V DLT++ SYYTG+ FEGY + LG P+CSGGRYD Sbjct: 240 KTALAEMTKLYEVLESYGASEYVKFDLTLVLHMSYYTGVVFEGYGNRLGVPLCSGGRYDE 299 Query: 303 LLQQFGRPVPSTGFSLKTNRILDGVSG 329 LL +F RP +TGF ++ + +++ ++G Sbjct: 300 LLSKFHRPAQATGFGVRIDLLVEALNG 326 >Q2B726.1 Q2B726_9BACI ATP phosphoribosyltransferase regulatory subunit Length = 389 Score = 285 bits (730), Expect = 4e-75, Method: Compositional matrix adjust. Identities = 144/332 (43%), Positives = 209/332 (62%), Gaps = 1/332 (0%) Query: 9 FEKPAGVRDYLPRAVTKLRKIEKDVLHCMSRWGYRQMITPTLEYYDTVGVASSTSDQKLY 68 FEKP G+RD LP ++ + M WGY+ M TP LEYY+TVG AS+T DQ+L+ Sbjct: 2 FEKPLGMRDTLPEIYETKSRVRSSIEEEMKSWGYQFMETPALEYYETVGSASATLDQQLF 61 Query: 69 KLLNNRGQALVLRSEMTAPVARVVSSLLKDEPLPLRLSYHANVXXXXXXXXXXXXXXXQT 128 KLL+ +G LVLR +MTAP+ARV +S L E LPLRL+Y ANV Q Sbjct: 62 KLLDQQGHTLVLRPDMTAPIARVAASRLLKEDLPLRLAYSANVYRAQQREGGRPAEFEQI 121 Query: 129 GVELVGDDSPEADAEVVALAISSLQAAGVKSFKIAMGHVGFLDGLFQEAVAGLPDAQEEL 188 GVEL+GDDS AD E +AL ISSL+ AG++ F++++GH+GF+ F++ V G + EL Sbjct: 122 GVELIGDDSISADGEGLALLISSLKKAGLEDFQLSVGHIGFVQEFFRQ-VLGTEERANEL 180 Query: 189 KSHLLNRDYVAFRETLRRLELSEAQKNELDGLLRLRGGKEICGQALELSSHPLARASIEH 248 L ++YV +RE ++ L LS K L L+LRGG+E QA L + R +I Sbjct: 181 TRFLYEKNYVGYREHVKNLPLSSIDKQRLLDFLQLRGGREAIEQAFSLIENNKGREAIVQ 240 Query: 249 LCKVWEVLVSYGVSQHVLIDLTMIGDFSYYTGMTFEGYASELGFPVCSGGRYDNLLQQFG 308 L ++W+ + +G + + +DLT++ SYYTG+ FE YA +GFP+ +GGRYD LL++FG Sbjct: 241 LERLWDTMADFGEGEKIKLDLTLVSHMSYYTGILFEVYAGNVGFPIGNGGRYDLLLKKFG 300 Query: 309 RPVPSTGFSLKTNRILDGVSGVPEEEELPILI 340 + +TGF+++ +R+L+ + G E+E L +I Sbjct: 301 KSSGATGFAIRLDRLLEALGGAGEKEPLHCII 332 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.136 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,181,177,833 Number of extensions: 83542475 Number of successful extensions: 205136 Number of sequences better than 1.0e-05: 2002 Number of HSP's gapped: 202220 Number of HSP's successfully gapped: 2008 Length of query: 407 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 269 Effective length of database: 1,760,596,133 Effective search space: 473600359777 Effective search space used: 473600359777 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 132 (55.5 bits)