BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0149.p (219 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00037445.1| COG0745: Response regulators consisting of a ... 262 4e-69 ref|NP_814664.1| DNA-binding response regulator [Enterococcus fa... 261 6e-69 gb|AAD10258.1| putative response regulator [Lactobacillus sakei] 256 3e-67 ref|NP_465270.1| similar to two-component response regulator [Li... 254 1e-66 ref|NP_471191.1| similar to two-component response regulator [Li... 253 3e-66 >ref|ZP_00037445.1| COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Enterococcus faecium] Length = 229 Score = 262 bits (669), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 120/219 (54%), Positives = 169/219 (77%), Gaps = 1/219 (0%) Query: 1 MIVEDDEKIRRIVADTLSKWKYEVTQVSSFDQVMDDFTASQPHLVLLDVNLPVYDGFYWC 60 M+VED+E IR+++ + L KW++E + F+QV DF +P LVLLD+NLPV DG+YWC Sbjct: 10 MVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFEREEPQLVLLDINLPVLDGYYWC 69 Query: 61 QQIRAVSKVPIIFLSSRNQNMDVIMAINMGADDFVQKPFDLGVLVAKVSALLRRNYTYQD 120 Q+IR VSKVPIIF+SSRN NMD+IMA+NMGADDFV K F + VL+AK++ALLRR+Y Y + Sbjct: 70 QKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKHFQIDVLIAKINALLRRSYNYTE 129 Query: 121 ESLQ-MAHRQLTFHLSNSSVEYEGQTAELSRNEFIILQTMMRNIGKIVSRDSLMQVLWSD 179 S + M+H +T ++ N S+E G+ +LS+NE+ +L +M++ GKI+SR+ L++ LW D Sbjct: 130 LSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRLLFILMKHNGKILSREKLLRALWDD 189 Query: 180 EQFIDDNTLTVNVNRLRRKIALLGLEDFIVTRKGMGYII 218 E+F+DDNTLTVN+NRLRRKI G++ +I T+ G GYI+ Sbjct: 190 ERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVGQGYIV 228 >ref|NP_814664.1| DNA-binding response regulator [Enterococcus faecalis V583] gb|AAO80734.1| DNA-binding response regulator [Enterococcus faecalis V583] gb|AAS49391.1| response regulator [Enterococcus faecalis] Length = 224 Score = 261 bits (668), Expect = 6e-69, Method: Compositional matrix adjust. Identities = 116/219 (52%), Positives = 168/219 (76%), Gaps = 1/219 (0%) Query: 1 MIVEDDEKIRRIVADTLSKWKYEVTQVSSFDQVMDDFTASQPHLVLLDVNLPVYDGFYWC 60 MIVED+ IR ++++ L KW++E + F+ V+DDF P LVL+D+NLPVYDG+YWC Sbjct: 5 MIVEDETTIRELISEELQKWQFETIGTTDFNDVLDDFQEENPQLVLMDINLPVYDGYYWC 64 Query: 61 QQIRAVSKVPIIFLSSRNQNMDVIMAINMGADDFVQKPFDLGVLVAKVSALLRRNYTYQD 120 Q+IR VSKVPIIF+SSR+ NMD+IMA+NMGADDFV KPF + VL+AK++ALLRR+Y Y D Sbjct: 65 QKIREVSKVPIIFISSRSTNMDMIMAMNMGADDFVTKPFQIDVLIAKINALLRRSYNYSD 124 Query: 121 -ESLQMAHRQLTFHLSNSSVEYEGQTAELSRNEFIILQTMMRNIGKIVSRDSLMQVLWSD 179 +S ++H +T ++ N +E G+ +LS+NE+ +L +M+ GKI++R+ L++ LW D Sbjct: 125 TDSEVLSHNGITLNVDNGRMEIRGEMIDLSKNEYRLLYLLMKKHGKILTREKLLRALWDD 184 Query: 180 EQFIDDNTLTVNVNRLRRKIALLGLEDFIVTRKGMGYII 218 E+F+DDNTLTVN+NRLR+KI G+ +I T+ G+GY++ Sbjct: 185 ERFVDDNTLTVNINRLRKKIEQAGIAGYIETKVGVGYMV 223 >gb|AAD10258.1| putative response regulator [Lactobacillus sakei] Length = 224 Score = 256 bits (654), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 119/219 (54%), Positives = 160/219 (73%), Gaps = 1/219 (0%) Query: 1 MIVEDDEKIRRIVADTLSKWKYEVTQVSSFDQVMDDFTASQPHLVLLDVNLPVYDGFYWC 60 MIVEDD I ++A+ L KW+ + FD + D F +PHLVLLD+NLPVYDGFYWC Sbjct: 5 MIVEDDPTIANLIAENLEKWQLKAIIPDDFDTIFDRFLTDKPHLVLLDINLPVYDGFYWC 64 Query: 61 QQIRAVSKVPIIFLSSRNQNMDVIMAINMGADDFVQKPFDLGVLVAKVSALLRRNYTYQD 120 ++IR VSKVPIIF+SSR+ NMD++M++NMG DDFV KPF + VL+AK++ALLRR Y Y D Sbjct: 65 RKIREVSKVPIIFISSRSTNMDMVMSMNMGGDDFVNKPFSMEVLIAKINALLRRTYNYVD 124 Query: 121 ESLQ-MAHRQLTFHLSNSSVEYEGQTAELSRNEFIILQTMMRNIGKIVSRDSLMQVLWSD 179 ++ + H L +L + + +LS+NE+ +LQ +MR G+IVSR+ L++ LW D Sbjct: 125 QNTDVIEHNGLLINLQSGGAQVGDTVVDLSKNEYKLLQFLMRQHGQIVSREKLLRALWDD 184 Query: 180 EQFIDDNTLTVNVNRLRRKIALLGLEDFIVTRKGMGYII 218 E+F+DDNTLTVN+NRLR+KI GLED+I T+ G GYII Sbjct: 185 ERFVDDNTLTVNINRLRKKIEQAGLEDYIQTKIGQGYII 223 >ref|NP_465270.1| similar to two-component response regulator [Listeria monocytogenes EGD-e] pir||AI1292 two-component response regulator homolog lmo1745 [imported] - Listeria monocytogenes (strain EGD-e) emb|CAC99823.1| lmo1745 [Listeria monocytogenes] Length = 225 Score = 254 bits (648), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 119/220 (54%), Positives = 160/220 (72%), Gaps = 2/220 (0%) Query: 2 IVEDDEKIRRIVADTLSKWKYEVTQVSSFDQVMDDFTASQPHLVLLDVNLPVYDGFYWCQ 61 IVEDDE IR + LSKW +E+ V F+ ++ +F A +P LV+LDVNLP +DGFYWC Sbjct: 6 IVEDDEVIRDTIRKHLSKWGFEIGVVEDFNNILQEFLAFEPQLVILDVNLPFFDGFYWCN 65 Query: 62 QIRAVSKVPIIFLSSRNQNMDVIMAINMGADDFVQKPFDLGVLVAKVSALLRRNYTYQD- 120 QIR VS VPIIFLSSRN MD IM +NMGAD +++KP DL VL+A+++ALLRR Y+Y D Sbjct: 66 QIREVSNVPIIFLSSRNSRMDQIMGMNMGADYYIEKPVDLDVLMARINALLRRTYSYADL 125 Query: 121 -ESLQMAHRQLTFHLSNSSVEYEGQTAELSRNEFIILQTMMRNIGKIVSRDSLMQVLWSD 179 E+ M H + H+ +++ + EL++NEF+IL +M+ G IVSRD +M+ LW D Sbjct: 126 EEANVMEHNNVFLHIDTNTLTHLEDKIELTKNEFLILYELMKQKGSIVSRDEIMRALWED 185 Query: 180 EQFIDDNTLTVNVNRLRRKIALLGLEDFIVTRKGMGYIIE 219 E F+DDNTLTVNV R+R+K+A +GL +FI T+KG GY+IE Sbjct: 186 ESFVDDNTLTVNVVRIRKKLAEIGLSEFIKTKKGQGYMIE 225 >ref|NP_471191.1| similar to two-component response regulator [Listeria innocua] pir||AG1664 two-component response regulator homolog lin1856 [imported] - Listeria innocua (strain Clip11262) emb|CAC97087.1| lin1856 [Listeria innocua] Length = 225 Score = 253 bits (645), Expect = 3e-66, Method: Compositional matrix adjust. Identities = 118/220 (53%), Positives = 161/220 (73%), Gaps = 2/220 (0%) Query: 2 IVEDDEKIRRIVADTLSKWKYEVTQVSSFDQVMDDFTASQPHLVLLDVNLPVYDGFYWCQ 61 IVEDDE IR + LSKW +E+ V F+ ++ +F + +P LV+LDVNLP +DGFYWC Sbjct: 6 IVEDDEVIRDTIRKHLSKWGFEIGVVDDFNNILQEFLSFEPQLVILDVNLPFFDGFYWCN 65 Query: 62 QIRAVSKVPIIFLSSRNQNMDVIMAINMGADDFVQKPFDLGVLVAKVSALLRRNYTYQD- 120 QIR VS VPIIFLSSRN MD IM +NMGAD +++KP DL VL+A+++ALLRR Y+Y D Sbjct: 66 QIREVSNVPIIFLSSRNSRMDQIMGMNMGADYYIEKPVDLDVLMARINALLRRTYSYADL 125 Query: 121 -ESLQMAHRQLTFHLSNSSVEYEGQTAELSRNEFIILQTMMRNIGKIVSRDSLMQVLWSD 179 E+ M H + H+ +++ + EL++NEF+IL +M+ G IVSRD +M+ LW D Sbjct: 126 EEANVMEHNNVFLHIDTNTLTHLEDKIELTKNEFLILYELMKQKGSIVSRDEIMRALWED 185 Query: 180 EQFIDDNTLTVNVNRLRRKIALLGLEDFIVTRKGMGYIIE 219 E F+DDNTLTVNV R+R+K+A +GL++FI T+KG GY+IE Sbjct: 186 ESFVDDNTLTVNVVRIRKKLAEIGLDEFIKTKKGQGYMIE 225 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.323 0.136 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 288,714,849 Number of extensions: 10365646 Number of successful extensions: 39871 Number of sequences better than 1.0e-05: 3556 Number of HSP's gapped: 38243 Number of HSP's successfully gapped: 3571 Length of query: 219 Length of database: 757,237,578 Length adjustment: 121 Effective length of query: 98 Effective length of database: 428,710,599 Effective search space: 42013638702 Effective search space used: 42013638702 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 123 (52.0 bits)