BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0148.p (327 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_346866.1| Sensory transduction histidine kinase [Clostrid... 211 2e-53 ref|NP_465266.1| similar to two-component sensor histidine kinas... 207 4e-52 ref|NP_471187.1| similar to two-component sensor histidine kinas... 205 1e-51 ref|ZP_00037444.1| COG0642: Signal transduction histidine kinase... 179 6e-44 gb|AAD10259.1| putative histidine kinase [Lactobacillus sakei] 179 6e-44 >ref|NP_346866.1| Sensory transduction histidine kinase [Clostridium acetobutylicum] pir||C96927 sensory transduction histidine kinase [imported] - Clostridium acetobutylicum gb|AAK78206.1| Sensory transduction histidine kinase [Clostridium acetobutylicum] Length = 339 Score = 211 bits (537), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 106/250 (42%), Positives = 164/250 (65%), Gaps = 3/250 (1%) Query: 76 EPLSLEAEGYREAIEQLQIQHIRALNEAQMQQKEHYDFIISWFHEVKTPIAVLRLMQQT- 134 EPL + E Y IE L + + + + +++ +F+ +W HE+KTPIA +L+ ++ Sbjct: 85 EPLEYKDEVYISIIEDLYKDYNERIVSLEKEFEDNNEFMTAWIHEIKTPIATAKLLLESG 144 Query: 135 EIDHSSLEEELSRIEHYIDQALYYSKLDTFNQDYEIVNCNLELLVKEAVKAHSKTFISKK 194 EID EE+ +I+ Y+++ LYYS+ D F++DY I N+ L+KE +K+HSK FI K Sbjct: 145 EIDSQLFMEEIEKIDDYVEKVLYYSRSDNFSKDYIISEVNISKLIKECIKSHSKIFIKKH 204 Query: 195 IKIRLDVQATM-VQSDSKWLSFIINQLVTNSLKYTGDQGEISFTTQVTPHEKLLIVRDNG 253 IK++L++ V++D KW FI+NQ+++N+LKYT D G I +EK++I+ DNG Sbjct: 205 IKLKLEIDERFNVETDKKWFLFILNQIISNALKYTNDMGNIIIKAFEDDNEKVVIIEDNG 264 Query: 254 IGIDRRDLPRVFNRGFTGTNGRT-YAKSTGMGLYLAQELSKKLGHYISCESEAGSFSEFT 312 IGI + DL R+F++ FTG NGR +K+TGMGLYL+ +L++KLGH I+ ES+ ++ Sbjct: 265 IGIKKEDLDRIFSKSFTGYNGRKENSKATGMGLYLSNKLAEKLGHNITIESKYNEGTKLY 324 Query: 313 IHFPKNHDPY 322 IHFPK D Y Sbjct: 325 IHFPKWCDYY 334 >ref|NP_465266.1| similar to two-component sensor histidine kinase [Listeria monocytogenes EGD-e] pir||AE1292 two-component sensor histidine kinase homolog lmo1741 [imported] - Listeria monocytogenes (strain EGD-e) emb|CAC99819.1| lmo1741 [Listeria monocytogenes] Length = 346 Score = 207 bits (526), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 107/255 (41%), Positives = 166/255 (65%), Gaps = 7/255 (2%) Query: 76 EPLSLEAEGYREAIEQLQIQHIRALNEAQMQQKEHYDFIISWFHEVKTPIAVLRLM---- 131 +P + E + + + + + +R +++ Q +Q+E++DFI+ W HEVKTP+ +++ Sbjct: 88 KPRTREQAFFNQLMAKKHKEELRTISKLQDKQQEYHDFILYWVHEVKTPVVASKMLINNP 147 Query: 132 --QQTEIDHSSLEEELSRIEHYIDQALYYSKLDTFNQDYEIVNCNLELLVKEAVKAHSKT 189 TE ++EEL+ I+ + QALY+S+LDTF++DY I NL ++V+E+VK HSK Sbjct: 148 DLNDTETIFKQIDEELTTIDKLVMQALYFSRLDTFSKDYFIQEQNLGVVVRESVKRHSKL 207 Query: 190 FISKKIKIRLDVQATMVQSDSKWLSFIINQLVTNSLKYTGDQGEISFTTQV-TPHEKLLI 248 FI KK+K+ L V++DSKWL FI++Q+++N+LKYT GE+ +K+L Sbjct: 208 FIGKKMKLDLQNVDMDVRTDSKWLGFILDQILSNALKYTKSGGEVKIWCDTEASGKKVLH 267 Query: 249 VRDNGIGIDRRDLPRVFNRGFTGTNGRTYAKSTGMGLYLAQELSKKLGHYISCESEAGSF 308 ++DNG GI DLPRVF +GFTG GR K+TGMGLYLA++++KKLGH I +SE+G Sbjct: 268 MKDNGRGIKEEDLPRVFEQGFTGNIGRQEKKATGMGLYLAKQMAKKLGHEICIQSESGVG 327 Query: 309 SEFTIHFPKNHDPYL 323 +E I+F + D L Sbjct: 328 TEVKIYFEQKDDYLL 342 >ref|NP_471187.1| similar to two-component sensor histidine kinase [Listeria innocua] pir||AC1664 two-component sensor histidine kinase homolog lin1852 [imported] - Listeria innocua (strain Clip11262) emb|CAC97083.1| lin1852 [Listeria innocua] Length = 346 Score = 205 bits (522), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 110/256 (42%), Positives = 169/256 (66%), Gaps = 9/256 (3%) Query: 76 EPLSLEAEGYREAIEQLQIQHIRALNEAQMQQKEHYDFIISWFHEVKTPIAVLRLM---- 131 +P + E + + + + + +R +++ Q +Q+E++DFI+ W HEVKTP+ +++ Sbjct: 88 KPRTREQAFFNQLMAKKHKEELRTISKLQDKQQEYHDFILYWVHEVKTPVVASKMLINNP 147 Query: 132 --QQTEIDHSSLEEELSRIEHYIDQALYYSKLDTFNQDYEIVNCNLELLVKEAVKAHSKT 189 T+ ++EEL I+ + QALY+S+LDTF++DY I NL +++E+VK HSK Sbjct: 148 DLNDTKTIFKQIDEELETIDKLVMQALYFSRLDTFSKDYFIQEQNLGAVMRESVKRHSKL 207 Query: 190 FISKKIKIRLDVQATMVQSDSKWLSFIINQLVTNSLKYTGDQGEISF--TTQVTPHEKLL 247 FI KK+K+ L V++DSKWL FII+Q+++N+LKYT D G+I T+VT +K+L Sbjct: 208 FIGKKMKLDLQNVDIDVRTDSKWLGFIIDQVLSNALKYTADGGDIQIWCDTEVTG-KKVL 266 Query: 248 IVRDNGIGIDRRDLPRVFNRGFTGTNGRTYAKSTGMGLYLAQELSKKLGHYISCESEAGS 307 ++DNG GI DLPRVF +GFTGT GR K+TGMGLYLA++++KKLGH I ES++ Sbjct: 267 HIKDNGRGIKEEDLPRVFEQGFTGTIGRQEKKATGMGLYLAKQMAKKLGHEICIESKSEI 326 Query: 308 FSEFTIHFPKNHDPYL 323 +E I+F + D L Sbjct: 327 GTEVRIYFEQKDDYLL 342 >ref|ZP_00037444.1| COG0642: Signal transduction histidine kinase [Enterococcus faecium] Length = 341 Score = 179 bits (455), Expect = 6e-44, Method: Compositional matrix adjust. Identities = 92/237 (38%), Positives = 152/237 (64%), Gaps = 7/237 (2%) Query: 87 EAIEQLQIQHIRALNEAQMQQKEHYDFIISWFHEVKTPIAVLRLMQQT---EID---HSS 140 E I QL +H + A Q++ D+I SW HE+K P++ +L+ ++ +ID ++ Sbjct: 96 EYINQLIREHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTL 155 Query: 141 LEEELSRIEHYIDQALYYSKLDTFNQDYEIVNCNLELLVKEAVKAHSKTFISKKIKIRLD 200 LE ELS+I+ Y++Q LYY++LD+F++DY I L+ +++ +++ + FI K I+ + Sbjct: 156 LENELSKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIV 215 Query: 201 VQATMVQSDSKWLSFIINQLVTNSLKYTGDQGEISFTTQVTPHEKLLIVRDNGIGIDRRD 260 + V +D+KW++FI NQL++N++KYT D G I + + L V+D+GIGI D Sbjct: 216 GEDHTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAED 275 Query: 261 LPRVFNRGFTGTNGR-TYAKSTGMGLYLAQELSKKLGHYISCESEAGSFSEFTIHFP 316 L R+F++GFTG NGR + STG+GLYLA+ L++KLG +++ ES G + T+ FP Sbjct: 276 LKRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFP 332 >gb|AAD10259.1| putative histidine kinase [Lactobacillus sakei] Length = 339 Score = 179 bits (455), Expect = 6e-44, Method: Compositional matrix adjust. Identities = 102/268 (38%), Positives = 159/268 (59%), Gaps = 14/268 (5%) Query: 59 RYMKNVQALRHLSDEDAE--PL----SLEAEGYREAIEQLQIQHIRALNEAQMQQKEHYD 112 ++ + +Q +R + EDA PL S E + +++ + L H +++ Q++ D Sbjct: 65 KWFRTIQ-IRLNAKEDALNWPLTGATSAEKQYFQKYVNSLLDYHQQSIERLMHAQQDQKD 123 Query: 113 FIISWFHEVKTPIAVLRLM------QQTEIDHSSLEEELSRIEHYIDQALYYSKLDTFNQ 166 FI W HE K P+A +L+ Q E + L +EL +IEHY++Q LYYS+LD+F++ Sbjct: 124 FIDGWVHESKVPLAATQLLVESIEDQIPEEKFNQLTDELVQIEHYVEQVLYYSRLDSFSK 183 Query: 167 DYEIVNCNLELLVKEAVKAHSKTFISKKIKIRLDVQATMVQSDSKWLSFIINQLVTNSLK 226 DY + L+ L+ + ++ + FI +I+ +L + V +D+KWL FI+NQ+V+N+LK Sbjct: 184 DYLVQEYALKPLINQTIRQNRNYFIQNRIQFKLTGEEQTVLTDAKWLVFILNQIVSNALK 243 Query: 227 YTGDQGEISFTTQVTPHEKLLIVRDNGIGIDRRDLPRVFNRGFTGTNGR-TYAKSTGMGL 285 YT G+I+ L V D+GIGI DLPRVF++GFTG NGR + +STG+GL Sbjct: 244 YTPQNGQITIDLAHDEQGVWLSVSDSGIGIPAEDLPRVFDKGFTGQNGRQSNQRSTGLGL 303 Query: 286 YLAQELSKKLGHYISCESEAGSFSEFTI 313 YLA+ LS KLGH C+ A + +F I Sbjct: 304 YLAKSLSNKLGHATLCQLNARKWCDFQI 331 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.320 0.135 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 430,637,819 Number of extensions: 16289724 Number of successful extensions: 55996 Number of sequences better than 1.0e-05: 1893 Number of HSP's gapped: 55866 Number of HSP's successfully gapped: 1898 Length of query: 327 Length of database: 757,237,578 Length adjustment: 126 Effective length of query: 201 Effective length of database: 415,135,104 Effective search space: 83442155904 Effective search space used: 83442155904 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 126 (53.1 bits)