BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0092.p (192 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_244753.1| NAD(P)H oxidoreductase [Bacillus halodurans] >g... 352 2e-96 ref|NP_694104.1| NAD(P)H oxidoreductase [Oceanobacillus iheyensi... 230 1e-59 ref|NP_415421.1| hypothetical protein b0901 [Escherichia coli K1... 134 1e-30 ref|NP_630532.1| putative NAD(P)H oxidoreductase [Streptomyces c... 122 3e-27 ref|NP_249916.1| probable NAD(P)H dehydrogenase [Pseudomonas aer... 105 4e-22 >ref|NP_244753.1| NAD(P)H oxidoreductase [Bacillus halodurans] pir||E84135 NAD(P)H oxidoreductase BH3885 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07604.1| NAD(P)H oxidoreductase [Bacillus halodurans] Length = 202 Score = 352 bits (903), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 166/192 (86%), Positives = 176/192 (91%) Query: 1 MKVLSVVSHPRQDSLTFGVAGRFVQGLADAGHDYEILDLHRIGFDPVLQGADEPDLSAAQ 60 MKVL+VVSHPR+DSLTF VA FV+GL +AGH+YEILDLH IGFDPVL+G DEPD S A+ Sbjct: 11 MKVLTVVSHPRKDSLTFEVAEHFVKGLTEAGHEYEILDLHEIGFDPVLKGVDEPDWSVAE 70 Query: 61 QSFSPEVEMEIRRMKEHDALAFIFPLWWWHLPAMLKGYIDRVWNNGFAYGSNHLHHQHVL 120 Q FSPEVEMEIRRMKEHDALA IFPLWWWHLPAMLKGYIDRVWNNGFAYG+NHLHHQHVL Sbjct: 71 QPFSPEVEMEIRRMKEHDALALIFPLWWWHLPAMLKGYIDRVWNNGFAYGANHLHHQHVL 130 Query: 121 WVALAGVSKDQMKKRNYDEMITHLLNVGIADYCGVPNSKVEFLYETLDSHPGHYEMLLNQ 180 W+ LAGVSK+QMKKRNYDEMITHLLNVGIADYCGV NSKVEFLYETLDSHP HYEMLLNQ Sbjct: 131 WIGLAGVSKEQMKKRNYDEMITHLLNVGIADYCGVSNSKVEFLYETLDSHPNHYEMLLNQ 190 Query: 181 AYHLGLNYAKDH 192 AY LGLNY K H Sbjct: 191 AYRLGLNYDKGH 202 >ref|NP_694104.1| NAD(P)H oxidoreductase [Oceanobacillus iheyensis HTE831] dbj|BAC15138.1| NAD(P)H oxidoreductase [Oceanobacillus iheyensis HTE831] Length = 190 Score = 230 bits (587), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 106/190 (55%), Positives = 135/190 (71%) Query: 1 MKVLSVVSHPRQDSLTFGVAGRFVQGLADAGHDYEILDLHRIGFDPVLQGADEPDLSAAQ 60 MKVL++V+HPR++SLT V RF++GL DAGH E +DL+R F+ L ADEP A + Sbjct: 1 MKVLTIVAHPREESLTMKVTNRFIEGLQDAGHTVEFIDLYRHEFEAALPVADEPIWDAEE 60 Query: 61 QSFSPEVEMEIRRMKEHDALAFIFPLWWWHLPAMLKGYIDRVWNNGFAYGSNHLHHQHVL 120 Q FSPEV EI RMK DALAFIFPLWWW +P ++KGYIDRVWN GFAYG+++LHH+HVL Sbjct: 61 QHFSPEVTKEIERMKSADALAFIFPLWWWSMPGIMKGYIDRVWNFGFAYGNSNLHHEHVL 120 Query: 121 WVALAGVSKDQMKKRNYDEMITHLLNVGIADYCGVPNSKVEFLYETLDSHPGHYEMLLNQ 180 W+ LA K +++KR Y+ M+ H NVG+ADYCG+P+S L ET + + L Q Sbjct: 121 WLGLAAADKKKLEKRKYNTMMEHYFNVGLADYCGIPSSTFHLLTETNKVNSQQLDNWLMQ 180 Query: 181 AYHLGLNYAK 190 AY LG NY K Sbjct: 181 AYELGRNYEK 190 >ref|NP_415421.1| hypothetical protein b0901 [Escherichia coli K12] sp|P43340|YCAK_ECOLI Putative NAD(P)H oxidoreductase ycaK pir||D64829 probable NAD(P)H2 dehydrogenase (quinone) (EC 1.6.99.2) ycaK - Escherichia coli (strain K-12) gb|AAC73987.1| orf, hypothetical protein [Escherichia coli K12] dbj|BAA35636.1| Hypothetical protein in pflA 3'region . [Escherichia coli K12] Length = 196 Score = 134 bits (337), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 74/186 (39%), Positives = 102/186 (54%), Gaps = 7/186 (3%) Query: 2 KVLSVVSHPRQDSLTFGVAGRFVQGLADAGHDYEILDLHRIGFDPVLQGADEPDLSAAQQ 61 ++ V +HPR DSLT +A Q + LDL+R F+PV+ DEPD + Sbjct: 5 RIYLVWAHPRHDSLTAHIADAIHQRAMERKIQVTELDLYRRNFNPVMTPEDEPDWKNMDK 64 Query: 62 SFSPEVEMEIRRMKEHDALAFIFPLWWWHLPAMLKGYIDRVWNNGFAYGSNH-LHHQHVL 120 +SPEV + EHD L +FPLWW+ PAMLKGYIDRVWNNG AYG H L V Sbjct: 65 RYSPEVHQLYSELLEHDTLVVVFPLWWYSFPAMLKGYIDRVWNNGLAYGDGHKLPFNKVR 124 Query: 121 WVALAGVSKDQMKKRNYDEMITHLLNVGIADYCGVPNSKVEFLYETL-----DSHPGHYE 175 WVAL G K+ + +++ I+ L + Y G+ ++ V FL T+ + H +Y+ Sbjct: 125 WVALVGGDKESFVQMGWEKNISDYLK-NMCSYLGIEDADVTFLCNTVVFDGEELHASYYQ 183 Query: 176 MLLNQA 181 LL+Q Sbjct: 184 SLLSQV 189 >ref|NP_630532.1| putative NAD(P)H oxidoreductase [Streptomyces coelicolor A3(2)] pir||T35934 probable NAD(P)H oxidoreductase - Streptomyces coelicolor emb|CAA22756.1| putative NAD(P)H oxidoreductase [Streptomyces coelicolor A3(2)] Length = 246 Score = 122 bits (307), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 66/165 (40%), Positives = 97/165 (58%), Gaps = 2/165 (1%) Query: 3 VLSVVSHPRQDSLTFGVAGRFVQGLADAGHDYEILDLHRIGFDPVLQGADEPDLSAAQQS 62 L VV+H R DSLT A R L +G+ ++LDLH GFDP + AD+PD +++ Sbjct: 31 ALVVVAHHRADSLTAHTARRTADRLEASGYRVDLLDLHAEGFDPRMTTADQPDWGDREKA 90 Query: 63 FSPEVEMEIRRMKEHDALAFIFPLWWWHLPAMLKGYIDRVWNNGFAYGSN--HLHHQHVL 120 +S E +RR+ + D + +FP++W +PA+LKG+IDRVWN GFAYG + L + +L Sbjct: 91 YSDEARAHMRRVLDADVVVAVFPVYWQSVPALLKGWIDRVWNYGFAYGRSKPRLAGKRML 150 Query: 121 WVALAGVSKDQMKKRNYDEMITHLLNVGIADYCGVPNSKVEFLYE 165 W+ LAG + D ++ L+ GIA YCG +S V L + Sbjct: 151 WLGLAGATADDPITEAMHALLETSLSEGIASYCGFSHSAVGLLTD 195 >ref|NP_249916.1| probable NAD(P)H dehydrogenase [Pseudomonas aeruginosa PA01] pir||H83491 probable NAD(P)H dehydrogenase PA1225 [imported] - Pseudomonas aeruginosa (strain PAO1) gb|AAG04614.1| probable NAD(P)H dehydrogenase [Pseudomonas aeruginosa PAO1] Length = 208 Score = 105 bits (263), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 64/192 (33%), Positives = 96/192 (50%), Gaps = 11/192 (5%) Query: 1 MKVLSVVSHPRQDSLTFGVAGRFVQGLADAGHDYEILDLHRIGFDPVLQGADEPDLSAAQ 60 M L VV+H SLT +A R +G+ AGH E DL GF+P AD + Q Sbjct: 1 MHALIVVAHHHPRSLTHALAARIAEGVVRAGHSAETADLAAEGFEPRFGLADHA-VHRGQ 59 Query: 61 QSFSPEVEMEIRRMKEHDALAFIFPLWWWHLPAMLKGYIDRVWNNGFAYG-------SNH 113 S +V E R+ D L ++P++WW +PA+LKG+IDRV++NG+A+ Sbjct: 60 ASPPADVLAEQARIDRADTLVLVYPIYWWSMPALLKGWIDRVFSNGWAFDYSIGGDLRKK 119 Query: 114 LHHQHVLWVALAGVSKDQMKKRNYDEMITHLLNVGIADYCGVPNSKVEFLYETLDSHPGH 173 L V+ V + G ++ Y + ++ GI DYCG + E L E+ + P Sbjct: 120 LQRLRVVLVGVGGADAGTFERHGYAGAMRTQIDHGIFDYCGARVVRSELLLESESADPIR 179 Query: 174 YEMLLNQAYHLG 185 + L+QA H+G Sbjct: 180 H---LDQALHIG 188 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.322 0.138 0.444 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 305,676,605 Number of extensions: 12599016 Number of successful extensions: 27160 Number of sequences better than 1.0e-05: 177 Number of HSP's gapped: 27059 Number of HSP's successfully gapped: 177 Length of query: 192 Length of database: 757,237,578 Length adjustment: 119 Effective length of query: 73 Effective length of database: 434,140,797 Effective search space: 31692278181 Effective search space used: 31692278181 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 122 (51.6 bits)