BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0018.p (537 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_241989.1| BH1123~unknown conserved protein [Bacillus halo... 125 3e-27 ref|NP_388577.1| similar to two-component response regulator [Ye... 114 8e-24 ref|NP_563003.1| two-component response regulator [Clostridium p... 112 2e-23 ref|NP_623880.1| AraC-type DNA-binding domain-containing protein... 111 5e-23 ref|NP_242776.1| two-component response regulator [Bacillus halo... 108 5e-22 >ref|NP_241989.1| BH1123~unknown conserved protein [Bacillus halodurans] pir||C83790 hypothetical protein BH1123 [imported] - Bacillus halodurans (strain C-125) dbj|BAB04842.1| BH1123~unknown conserved protein [Bacillus halodurans] Length = 526 Score = 125 bits (314), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 60/136 (44%), Positives = 89/136 (65%) Query: 11 LYKLFIADDEQLVVETLSEMIDWDAFGVRIIGTANNGKQALERILQSDPDIVLTDIRMPG 70 ++K+ I DDE+ VV L ++I W A G +G A NG++ L+ + ++ P IVLTDI MP Sbjct: 1 MWKVVIIDDEEHVVRGLKKIISWKALGCECVGEAANGRRGLDIVRETSPHIVLTDIYMPI 60 Query: 71 LNGLDLIRTLKENGRKAECIIVSGYSEFEYAKEAIELEAVDYLIKPAELDEVARTVSRAI 130 + GLD+I+ L+E+G E +I+SGYSEFE+A++A++L DYL KPA +D + + R I Sbjct: 61 MYGLDMIQILREDGFDGEVVILSGYSEFEHARKAMQLNITDYLSKPASVDTIETVLKRVI 120 Query: 131 QRLGRKADQTGNHPEL 146 +L K Q G EL Sbjct: 121 NKLEEKQRQQGYLQEL 136 Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 40/149 (26%), Positives = 81/149 (54%) Query: 370 DYGIKIERVTGDRTRLIEEIHEAPDWASLKKICVDLAQSVQFYLNVTKTTLKEKVVHEIK 429 D GI I+ + + L + + + +W + + + + ++ + ++++ ++ Sbjct: 371 DIGILIQEMFDEDFDLAQHLTKQGNWQEWIRFLCEQIEHICYHQQWDENIKHKQLIEQVM 430 Query: 430 AYLESHYHENIQLDQLAERFDLNASYVSNLYSKSTGQTILEYVTLLRIRQAKKMLRGSSF 489 Y+E H ENI L +A+ ++ +Y+ ++ K G++ YVT LR+ +AKKM++ +F Sbjct: 431 IYIEKHLAENITLQDIADELYISRNYLGQIFKKVVGESFKNYVTRLRMEKAKKMIQEGNF 490 Query: 490 KISKISTNVGYDNQRYFCQVFKKHVGVSP 518 I ++S VGY N YF +FKK+ G +P Sbjct: 491 LIYEVSEKVGYVNPAYFTTMFKKYTGYTP 519 >ref|NP_388577.1| similar to two-component response regulator [YesM] [Bacillus subtilis] pir||E69796 two-component response regulator [YesM] homolog yesN - Bacillus subtilis emb|CAB12515.1| yesN [Bacillus subtilis subsp. subtilis str. 168] Length = 368 Score = 114 bits (284), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 47/126 (37%), Positives = 85/126 (67%) Query: 11 LYKLFIADDEQLVVETLSEMIDWDAFGVRIIGTANNGKQALERILQSDPDIVLTDIRMPG 70 +YK+ +ADDE+++++ ++ +I+W++ G +IG A NG +A E+I+ P IV+TD++MPG Sbjct: 1 MYKILLADDERIILDGMAGIIEWESLGASLIGKAQNGHEAYEKIVHKQPHIVITDVKMPG 60 Query: 71 LNGLDLIRTLKENGRKAECIIVSGYSEFEYAKEAIELEAVDYLIKPAELDEVARTVSRAI 130 ++GL+LI+ + + I++SG+ EFEYAKEA++ YL+KP ++ ++ I Sbjct: 61 MDGLELIKKVSAVSPSVQFIVLSGFGEFEYAKEAMKYGVKHYLLKPCNEQQIISSLEEII 120 Query: 131 QRLGRK 136 L R+ Sbjct: 121 AELKRQ 126 Score = 60.1 bits (144), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 28/83 (33%), Positives = 50/83 (60%), Gaps = 2/83 (2%) Query: 451 LNASYVSNLYSKSTGQTILEYVTLLRIRQAKKMLR-GSSFKISKISTNVGY-DNQRYFCQ 508 +N Y+ L+ + TG+ +YVT +R+ A K ++ +S+I+ +G+ DN +YF Sbjct: 286 MNPDYLGKLFKQETGEKFSQYVTRVRLEHAMKQMKIRRDVSVSEIAEEIGFGDNPKYFSL 345 Query: 509 VFKKHVGVSPSQYREEHMIKSEG 531 VFKK+ G++PS++R + S G Sbjct: 346 VFKKYTGLTPSEFRRKQGGASAG 368 >ref|NP_563003.1| two-component response regulator [Clostridium perfringens] dbj|BAB81793.1| two-component response regulator [Clostridium perfringens str. 13] Length = 507 Score = 112 bits (281), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 48/130 (36%), Positives = 91/130 (70%) Query: 11 LYKLFIADDEQLVVETLSEMIDWDAFGVRIIGTANNGKQALERILQSDPDIVLTDIRMPG 70 +YK+ +ADDE L+++ L +I+W+ G+ I+ A+NG++A+++ ++ DIV+TDI MP Sbjct: 1 MYKVMLADDENLILQGLENIIEWEELGLEIVNKASNGQEAIDKFKENPVDIVVTDINMPQ 60 Query: 71 LNGLDLIRTLKENGRKAECIIVSGYSEFEYAKEAIELEAVDYLIKPAELDEVARTVSRAI 130 + GL+L++ LK+ + II+SGY +F YAK+AIEL +Y++KP + +E+ +T+ I Sbjct: 61 VTGLELLKELKKINSDVKFIILSGYDDFSYAKKAIELGVENYILKPIDEEELEKTLKNTI 120 Query: 131 QRLGRKADQT 140 ++ ++ ++ Sbjct: 121 NKIKQEKEEN 130 Score = 74.7 bits (182), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 37/123 (30%), Positives = 74/123 (60%), Gaps = 4/123 (3%) Query: 401 ICVDLAQSVQFYLNVTKTTLK-EKVVHEIKAYLESHYHENIQLDQLAERFDLNASYVSNL 459 +C ++ + ++ + TT+K V+ +I +Y+ +Y+E + L LA+++ +N SY+ + Sbjct: 383 LCSEIREVIEL---MHPTTIKYSPVIQQIISYVNENYYEEVSLKTLAQKYHINTSYLGQV 439 Query: 460 YSKSTGQTILEYVTLLRIRQAKKMLRGSSFKISKISTNVGYDNQRYFCQVFKKHVGVSPS 519 ++K G + EY+ + +AK+++ ++ KI+ I+ VGY + YF + FKK+ GV PS Sbjct: 440 FTKEVGCSFSEYLNKTKNMKAKELILNTNMKINDIAKKVGYLDTSYFYRKFKKYYGVCPS 499 Query: 520 QYR 522 R Sbjct: 500 TLR 502 >ref|NP_623880.1| AraC-type DNA-binding domain-containing proteins [Thermoanaerobacter tengcongensis] gb|AAM25484.1| AraC-type DNA-binding domain-containing proteins [Thermoanaerobacter tengcongensis] Length = 519 Score = 111 bits (277), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 55/117 (47%), Positives = 81/117 (69%) Query: 13 KLFIADDEQLVVETLSEMIDWDAFGVRIIGTANNGKQALERILQSDPDIVLTDIRMPGLN 72 KLFIADDE VVE + +IDW G+ ++G A +G++AL +I PDIVL DIRMP L+ Sbjct: 2 KLFIADDEVEVVEGILTLIDWKGNGIELVGYAMDGEEALYKIKSLKPDIVLIDIRMPKLD 61 Query: 73 GLDLIRTLKENGRKAECIIVSGYSEFEYAKEAIELEAVDYLIKPAELDEVARTVSRA 129 GL++I + G + + II+SGY +F +AK+AIEL++ YL+KP +E+ + V +A Sbjct: 62 GLEVIEKAQGEGIRFKSIILSGYDDFYFAKKAIELKSFSYLLKPCRPEEILKEVLKA 118 Score = 77.0 bits (188), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 33/103 (32%), Positives = 65/103 (63%) Query: 421 KEKVVHEIKAYLESHYHENIQLDQLAERFDLNASYVSNLYSKSTGQTILEYVTLLRIRQA 480 K ++ + Y++ +Y ++I L+ +A+ + +Y+S L+ K + Y+ +R+ +A Sbjct: 415 KNPIIKDAVEYIDKNYDKDISLESVAKEVYVTPAYLSILFKKEMNINFVSYLHKVRVEKA 474 Query: 481 KKMLRGSSFKISKISTNVGYDNQRYFCQVFKKHVGVSPSQYRE 523 KK+L S K +++ VG+ +++YF QVFKK+ G++PSQYR+ Sbjct: 475 KKLLEDRSLKTYQVANMVGFGDEKYFSQVFKKYTGLTPSQYRD 517 >ref|NP_242776.1| two-component response regulator [Bacillus halodurans] pir||F83888 two-component response regulator BH1910 [imported] - Bacillus halodurans (strain C-125) dbj|BAB05629.1| two-component response regulator [Bacillus halodurans] Length = 506 Score = 108 bits (269), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 49/125 (39%), Positives = 79/125 (63%) Query: 11 LYKLFIADDEQLVVETLSEMIDWDAFGVRIIGTANNGKQALERILQSDPDIVLTDIRMPG 70 +Y + I DDE +V E L +I W+ +G R+I TA NGK+ + Q PD+++ DIRMP Sbjct: 1 MYDVMIVDDEAMVREGLKALISWEEYGFRVIDTARNGKEGFTKYRQLSPDLMIVDIRMPE 60 Query: 71 LNGLDLIRTLKENGRKAECIIVSGYSEFEYAKEAIELEAVDYLIKPAELDEVARTVSRAI 130 ++GL LI +++ II+SG+S+F YAK+A+ + DYL+KP + DE+ ++ + Sbjct: 61 VDGLSLIESIRAEDSAIHFIILSGHSDFNYAKKALGCQCDDYLLKPLDEDELIDSLKKVY 120 Query: 131 QRLGR 135 R+ R Sbjct: 121 GRITR 125 Score = 73.9 bits (180), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 37/131 (28%), Positives = 74/131 (56%), Gaps = 1/131 (0%) Query: 395 WASLKKICVDLAQSVQFYLNVTKTTLKEKVVHEIKAYLESHYHENIQLDQLAERFDLNAS 454 + L I L + +++ ++ + ++ ++ A + Y +N++L+ LA F+ N + Sbjct: 369 FEHLPGIMAFLTKQLKYVIDCMDNGQPDLLLRKMIALIHKDYAKNLRLETLASVFNYNRA 428 Query: 455 YVSNLYSKSTGQTILEYVTLLRIRQAKKMLRGSSFKISKISTNVGYDNQRYFCQVFKKHV 514 Y+ L+ TG+ Y+ +RI K++L+ +K+ +++ +GY N YF + FKK+V Sbjct: 429 YLGKLFKNYTGEYFNTYLDKVRIENGKRLLQ-KGYKVYEVAEKIGYANVDYFHRKFKKYV 487 Query: 515 GVSPSQYREEH 525 GVSPS +R+ H Sbjct: 488 GVSPSTFRKRH 498 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.135 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 774,370,449 Number of extensions: 31463817 Number of successful extensions: 98407 Number of sequences better than 1.0e-05: 2586 Number of HSP's gapped: 100357 Number of HSP's successfully gapped: 2642 Length of query: 537 Length of database: 757,237,578 Length adjustment: 130 Effective length of query: 407 Effective length of database: 404,274,708 Effective search space: 164539806156 Effective search space used: 164539806156 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 128 (53.9 bits)