BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0596.0026.p (594 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_242775.1| two-component sensor histidine kinase [Bacillus... 414 e-114 ref|NP_242976.1| BH2110~unknown conserved protein [Bacillus halo... 190 7e-47 ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongen... 167 8e-40 ref|NP_782429.1| two-component sensor kinase yesM [Clostridium t... 166 2e-39 ref|NP_244314.1| two-component sensor histidine kinase [Bacillus... 164 6e-39 >ref|NP_242775.1| two-component sensor histidine kinase [Bacillus halodurans] pir||E83888 two-component sensor histidine kinase BH1909 [imported] - Bacillus halodurans (strain C-125) dbj|BAB05628.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 597 Score = 414 bits (1064), Expect = e-114, Method: Compositional matrix adjust. Identities = 231/586 (39%), Positives = 342/586 (58%), Gaps = 3/586 (0%) Query: 3 LVRIMNDMKMKKKLAVTFISAAVXXXXXXXXXXXXXXREIVINDAFTQLSNNVERVRKRT 62 L++ +NDMK++ KL F+ R I DA Q NVERV++RT Sbjct: 5 LIQTINDMKLRDKLMFMFVVVVFFPMMIVGIFLTNELRSNAIQDAIQQSRVNVERVKERT 64 Query: 63 EELIKVPLNISYRLTIDNRMKKVAAQKYESYTEVIQAYREYTDIRDYIQLYKEISSIRVY 122 E++ VP+ I+ L D R ++ Q+YE+ +V+ AY +Y + +Y+Q Y EI +++ Y Sbjct: 65 TEVLNVPVLIANNLQFDERFIELVNQEYETTYDVVDAYLQYMNFTNYLQYYSEIHNMKYY 124 Query: 123 VVNPGALNNWEFIQPDNAIMAEGWYKEAIEQKGLAGWNLIKDE-RNGSEQLSLVRSFPVD 181 N +NNW I P E W+KEA+ W ++DE + LS+V+ Sbjct: 125 SENTSLMNNWVII-PVEHEAGEEWFKEAMADPAYYRWFYLEDETKKNQAYLSMVKRLNFL 183 Query: 182 SLGEKGVLAINVDKQQLRSILDQEPFTTLIVDDRNRVVGSNEGEFFGKNLSEIDGDAKIL 241 G GVL I VD ++L IL QE FTT+IVD+RNR+ +N+ E+ GK+L E+ +++ Sbjct: 184 EYGSAGVLVITVDPRKLDRILQQESFTTMIVDERNRIAATNQREYIGKDLHEVIDFHEMI 243 Query: 242 SRQEGSYDTVVNGKASKVVMVNLNPENSWNGLRIISIFSVSEITREANQVIRLGAVVITV 301 Y+ +NG+ S++++ L + S + L+IISI + I ++A ++ +GA V Sbjct: 244 QEGPAIYEGKMNGEPSQIIVDYLTLQMSQSELKIISIVTKEHIMKDAKRLSIMGATVTMG 303 Query: 302 SLMFAVLLIYXXXXXXXXXXXXXXKHMSKAGAGSWETYIHIDSKDEIGLLSKQFNALIRS 361 + AVLLI + +++ +G +T I +D KDEIG LS QFN ++ + Sbjct: 304 GMAVAVLLIVHFSWLISKRLSHLSERINQVASGDLKTKIVVDGKDEIGQLSVQFNQMVAN 363 Query: 362 VHDLVQEVQETNHQKNLVEQRQSEMKFKMLASQIHPHFLFNSLESIRMEAHIRRQDEIAE 421 + L+ +V ETN QK L+E+ Q+E+K KMLASQI+PHFLFN+LESIRM++H++ + EIA+ Sbjct: 364 LRSLIHQVHETNRQKRLLEKSQNEIKLKMLASQINPHFLFNTLESIRMKSHMKGETEIAK 423 Query: 422 AVWLLSTLLRSSLEAGNGNIPLREELERVRCYLEMQKFRYEDRLEYHLTVDADLEVMPVP 481 V L L+R SLE +IPLR EL+ VRCYLE+Q FRY DRL Y L +D E++ + Sbjct: 424 VVKQLGKLMRKSLEVTGHHIPLRNELDMVRCYLEIQTFRYGDRLHYELYIDPQSEMVEIL 483 Query: 482 PLIIQPLVENSVLHGLDNREEGAVITVEVKKMPKGARVKVCDNGAGFTAERLAEIQAELA 541 PLIIQPLVEN+V+HGL+ E+G +T+ V V D+G G E+L IQ L Sbjct: 484 PLIIQPLVENAVIHGLERTEDGGTVTISTIVNGNDLTVIVNDDGCGMDEEKLEAIQNMLH 543 Query: 542 ESVHEQESKRIGMRNVNDRLVLLYGESSALSIESGSGTGTAITFFI 587 E + +IG+ NV+ RL L YG++S L IES G GT + F I Sbjct: 544 HP-QEVDGNKIGLLNVHKRLQLTYGKTSGLIIESAKGKGTCVRFTI 588 >ref|NP_242976.1| BH2110~unknown conserved protein [Bacillus halodurans] pir||F83913 hypothetical protein BH2110 [imported] - Bacillus halodurans (strain C-125) dbj|BAB05829.1| BH2110~unknown conserved protein [Bacillus halodurans] Length = 585 Score = 190 bits (483), Expect = 7e-47, Method: Compositional matrix adjust. Identities = 148/547 (27%), Positives = 263/547 (48%), Gaps = 36/547 (6%) Query: 55 VERVRKRTEELIKVPLNISYRLTIDNRMKKVAAQKYESYTEVIQAYREYTDIRDYIQ--- 111 V+++ + + IS + R+ +YE+ + I+AY Y +R+Y + Sbjct: 56 VDQITNEFNNAVDQAIGISSGFYTNTRIYDFFETEYETAIDYIEAYDFY--LREYSRFSP 113 Query: 112 LYKEISSIRVYVVNPGALNNWEFIQPDNAIMAEGWYKEAIEQKGLAGWNLI--KDERNGS 169 LY I SI Y NP + E WY+ E A +I + S Sbjct: 114 LYYSIQSISFYTDNPSFIYAGGIRPLTEHTKEEKWYRLLTE----ANHPIIIRTNPATDS 169 Query: 170 EQLSLVR--SFPVDSLGEKGVLAINVDKQQLRSILDQEPFT---TLIVDDRNRVVGSNEG 224 S++R + + K ++ I+++ ++ I + FT L+ +RN SNE Sbjct: 170 GLFSVIRELDYHKNKYNHKKIVRIDLNPLTIKQIFNNAAFTGEVYLLNGERNIEFSSNEE 229 Query: 225 EFFGKNLSEIDGDAKILSRQEGSYDTVVNGKASKVVMVNLNPENSWNGLRIISIFSVSEI 284 ++ DA E DT+ +K M++ +N G R+ S +EI Sbjct: 230 --VNWRTEQLHFDA-----LEFPEDTIF----TKERMLS---QNYLEGWRVAGTISENEI 275 Query: 285 TREANQVIRLGAVVITVSLMFAVLLIYXXXXXXXXXXXXXXKHMSKAGAGSWETYIHIDS 344 E + ++ +++L+F LLI KHM + ++ Sbjct: 276 LEELYKSREFIVILASINLLFPTLLIVLISKSIHSRLLRVLKHMKRMKKQKFDIINFPGD 335 Query: 345 KDEIGLLSKQFNALIRSVHDLVQEVQETNHQKNLVEQRQSEMKFKMLASQIHPHFLFNSL 404 KDEIG L+ +FN + ++++ L+ EV +N +K ++ R+ + + L SQI+PHFLFN+L Sbjct: 336 KDEIGELTNEFNKMSQTINRLINEVYASNIEKKDLQLREKQAQLSALQSQINPHFLFNAL 395 Query: 405 ESIRMEAHIRRQDEIAEAVWLLSTLLRSSLEAGNGNIPLREELERVRCYLEMQKFRYEDR 464 E+IRM + I+ + E A+ + ++ + R+SL G + +R+EL + C+LE+QK+R+ D+ Sbjct: 396 ETIRMRSMIKGEKETAKIIQNMAKIFRNSLTWGKDWVTVRDELCLIICFLEIQKYRFGDK 455 Query: 465 LEYHLTVDADLEVMPVPPLIIQPLVENSVLHGLDNREEGAVITVEVKKMPKGARVKVCDN 524 +EY L +D + +P ++ P VEN+ +HG+++ +E +I + V+K ++ DN Sbjct: 456 MEYELDIDEEAYDYIIPNMVFLPFVENASIHGIESVKEKGIIQIRVEKNDGEIVYEISDN 515 Query: 525 GAGFTAERLAEIQAELAESVHEQES--KRIGMRNVNDRLVLLYGESSALSIESGSGTGTA 582 GAG E+L A L E++ +E+ + +G++NV RL L Y SI S G GT Sbjct: 516 GAGMDEEKL----ASLIETLKNEENMGENVGIKNVYYRLKLHYKNHFDFSINSRPGQGTT 571 Query: 583 ITFFIPG 589 + +P Sbjct: 572 VQIKLPA 578 >ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongensis] gb|AAM25485.1| predicted ATPase [Thermoanaerobacter tengcongensis] Length = 593 Score = 167 bits (422), Expect = 8e-40, Method: Compositional matrix adjust. Identities = 127/463 (27%), Positives = 237/463 (51%), Gaps = 37/463 (7%) Query: 145 GWYKEAIEQKGLAGW----NLIKDE--RNGSEQLSLVRSF-PVDSLGEKGVLAINVDKQQ 197 +Y+E +E+ G W NL D +N ++++ R ++ +G+L I ++ Sbjct: 145 SFYREVLEKNGAPMWLSLENLPFDLIIKNNYPKIAMARVLLDFNTYKPEGLLVICINIPT 204 Query: 198 LRSILDQ---EPFTTLIVDDRNRVVGSNEGEFFG-KNLSEIDGDAKILSRQEGSYDTVVN 253 + + + E + + DRN + S + F G S + AK L ++ + V+N Sbjct: 205 IEKVYSENLKEKESAFFIADRNGNIISFKSTFSGFTPKSAQNILAKYLKDKQ---NVVIN 261 Query: 254 GKASKVVMVNLN-PENSWNGLRIISIFSVSEITREANQVIRLGAV-----VITVSLMFAV 307 +SK+++ + P + W R++S+ S+ + A IR+ + ++ L+FA Sbjct: 262 INSSKLLVTSSPIPTSDW---RLVSVVSL----KNAINSIRISFIEFYLRILVFCLLFAF 314 Query: 308 LLIYXXXXXXXXXXXXXXKHMSKAGAGSWETYIHID--SKDEIGLLSKQFNALIRSVHDL 365 L+ M K G+ E + + SKDEI ++ K++N ++ ++DL Sbjct: 315 LVSMYFSRALTHPLERLANSMKKVRQGNLEEKVEFEYHSKDEIAIVIKEYNRMVERINDL 374 Query: 366 VQEVQETNHQKNLVEQRQSEMKFKMLASQIHPHFLFNSLESIRMEAHIRRQDEIAEAVWL 425 + + + + +R++E+K L +QI+PHFL+N+L++I +A + E++E ++ Sbjct: 375 INRILKLE-----INKREAELK--ALEAQINPHFLYNTLDTIFWKAEKAKDRELSEMIYS 427 Query: 426 LSTLLRSSLEAGNGNIPLREELERVRCYLEMQKFRYEDRLEYHLTVDADLEVMPVPPLII 485 LS L R +L G I +R E E + YL +Q RY+++ +Y + + ++ +P LI+ Sbjct: 428 LSRLFRLTLNRGEEFIQVRGEKELIERYLFLQSKRYKNKFKYSVKISDEILDYYIPKLIL 487 Query: 486 QPLVENSVLHGLDNREEGAVITVEVKKMPKGARVKVCDNGAGFTAERLAEIQAELAESVH 545 QP VEN+++HGL+N E + + V +K + + + DNG G + E L +++ ES + Sbjct: 488 QPFVENAIVHGLENNSEESFVEVIGEKEGENLKFIIKDNGPGMSEETLEKLK-RFIESEN 546 Query: 546 EQESKRIGMRNVNDRLVLLYGESSALSIESGSGTGTAITFFIP 588 +E +RNVN+RL L YG+ L IES G GT I+ +P Sbjct: 547 IEEKVGYAIRNVNERLRLYYGDKYELKIESRQGEGTTISLILP 589 >ref|NP_782429.1| two-component sensor kinase yesM [Clostridium tetani E88] gb|AAO36366.1| two-component sensor kinase yesM [Clostridium tetani E88] Length = 577 Score = 166 bits (419), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 90/262 (34%), Positives = 151/262 (57%), Gaps = 10/262 (3%) Query: 327 HMSKAGAGSWETYIHIDSKDEIGLLSKQFNALIRSVHDLVQEVQETNHQKNLVEQRQSEM 386 +M + G++++Y I + DEI +L + FN ++ + L+ +V + QK R +E+ Sbjct: 316 NMLEISKGNFDSYYEIKNNDEISILGQVFNQMLTDIKRLINKVYQVEKQK-----RSAEL 370 Query: 387 KFKMLASQIHPHFLFNSLESIRMEAHIRRQDEIAEAVWLLSTLLRSSLEAGNGNIPLREE 446 + +L SQI+PHFL+N+L++I+ +A E+ + + LS R SL G I + +E Sbjct: 371 R--VLQSQINPHFLYNTLDTIQWKALEYNAFEVVDMINYLSNFFRISLSDGKEFITISDE 428 Query: 447 LERVRCYLEMQKFRYEDRLEYHLTVDADLEVMPVPPLIIQPLVENSVLHGLDNREEGAVI 506 + V YLE+QK RY+D++ Y + VD+ L+ +P LI+QPLVENS+ HGL ++ +I Sbjct: 429 VAHVSNYLEIQKIRYKDKISYSMDVDSSLDQYLIPKLIVQPLVENSIYHGLKLQKHKGII 488 Query: 507 TVEVKKMPKGARVKVCDNGAGFTAERLAEIQAELAESVHEQESKRIGMRNVNDRLVLLYG 566 V + +KV DNG G E+L ++ L ES+ E+ G+ N+N+RL L +G Sbjct: 489 NVSISSKDGFLFIKVIDNGLGMDVEQLRTLRKNLWESI---ETNHYGLYNINERLKLAFG 545 Query: 567 ESSALSIESGSGTGTAITFFIP 588 + ++ I+S GT + IP Sbjct: 546 KKYSIEIKSELKIGTQVLLRIP 567 >ref|NP_244314.1| two-component sensor histidine kinase [Bacillus halodurans] pir||G84080 two-component sensor histidine kinase BH3447 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07166.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 602 Score = 164 bits (415), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 124/505 (24%), Positives = 240/505 (47%), Gaps = 40/505 (7%) Query: 106 IRDYIQLYKEISSIRVYVVNPGALNNWEFIQPDNAIMAEGWYKEAIEQKGLAGWNLIKDE 165 ++++ LY EI+ I V L+N + + + E WY++A+E KG+A LI Sbjct: 105 LQNFTTLYPEIAGILVVNQQGDYLSNELYTRSSFNLNQESWYRQAVENKGIA--KLIGKP 162 Query: 166 RNG----------SEQLSLVRSFPVDSLGE-KGVLAIN----VDKQQLRSILDQEPFTTL 210 + E +++VR+ + GE KGV+ I+ V ++ +R + + + Sbjct: 163 QGRRITSHVHYREDEVVTVVRAIIDSTTGEEKGVILIDLKLRVIEEAVRDVRLGKSGYLM 222 Query: 211 IVDDRNRVVGSNEGEFFGKNLSEIDGDAKILSRQEGSYDTVVNGKASKVVMVNLNPENSW 270 +VD + + S + E D + S+ G + V G+ ++ + ++++ Sbjct: 223 VVDQKGDPIYSPAPSI----MYEQSFDHR-FSQNYGIFTEEVEGERYQL----MYQQSAF 273 Query: 271 NGLRIISIFSVSEITREANQVIRLGAVVITVSLMFAVLLIYXXXXXXXXXXXXXXKHMSK 330 G +I +FS + E Q++ + + Y M K Sbjct: 274 TGWTLIGVFSTDQSVEEVQQILFYVVTFVFFVCFVGITASYFLSYTISRPINQLMLAMQK 333 Query: 331 AGAGSWETYIHIDSKDEIGLLSKQFNALIRSVHDLVQEVQETNHQKNLVEQRQSEMKFKM 390 A +G + + +DE+G L + FN +I + L+ + E+++ E + Sbjct: 334 AESGDLTSRYEGEEQDEVGRLGRSFNTMIEQIGKLISLTERQ-------ERKKREAELHS 386 Query: 391 LASQIHPHFLFNSLESIRMEAHIRRQDEIAEAVWLLSTLLRSSLEAGNGNIPLREELERV 450 L + I PHFL+N+L++I+ A + ++A+ V LS L R L G IPL +E+E + Sbjct: 387 LQANIKPHFLYNTLDTIQWMARKKNASDVADLVGALSKLFRIGLSKGGTIIPLVDEIEHI 446 Query: 451 RCYLEMQKFRYEDRLEYHLTVDADLEVMPVPPLIIQPLVENSVLHGLDNREEGAVITVEV 510 + YL++Q RY+++L Y L + +++E + + +++QP+VEN++ HG+ R +IT+E Sbjct: 447 KNYLQIQSVRYKNKLNYSLVMPSNMERLSILKIVLQPIVENAIYHGIKERRGPGLITIEA 506 Query: 511 KKMPKGARVKVCDNGAGFTAERLAEIQAELAESVHEQE-------SKRIGMRNVNDRLVL 563 ++ +++ DNG G E L +++ + + + + +K G+ NV+ RL L Sbjct: 507 ERENDMLIIRIRDNGKGIKPETLQQLRTNVNLFLEKGDKEGGQRLTKGYGLINVHARLRL 566 Query: 564 LYGESSALSIESGSGTGTAITFFIP 588 +GE + I+S GT +T F P Sbjct: 567 TFGEPYGVKIDSVFNEGTVVTIFHP 591 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.317 0.134 0.372 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 767,354,643 Number of extensions: 30158244 Number of successful extensions: 93811 Number of sequences better than 1.0e-05: 198 Number of HSP's gapped: 93522 Number of HSP's successfully gapped: 198 Length of query: 594 Length of database: 757,237,578 Length adjustment: 131 Effective length of query: 463 Effective length of database: 401,559,609 Effective search space: 185922098967 Effective search space used: 185922098967 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 129 (54.3 bits)