BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0587.0018.p (443 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||T44807 mycosubtilin synthetase chain mycB [imported] - Baci... 298 2e-79 dbj|BAB69699.1| iturin A synthetase B [Bacillus subtilis] 295 1e-78 sp|O68008|BACC_BACLI Bacitracin synthetase 3 (BA3) [Includes: AT... 290 7e-77 pir||JX0340 gramicidin S synthase 2 - Bacillus brevis >gi|511490... 288 3e-76 emb|CAE02631.1| surfactin synthetase B [Bacillus amyloliquefaciens] 287 3e-76 >pir||T44807 mycosubtilin synthetase chain mycB [imported] - Bacillus subtilis gb|AAF08796.1| MycB [Bacillus subtilis] Length = 5369 Score = 298 bits (762), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 164/423 (38%), Positives = 247/423 (58%), Gaps = 4/423 (0%) Query: 12 YYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTTIE 71 YYP S AQ+ +++ + L G +YN+ + +KG LD +L++A KL++RHESLRT + Sbjct: 3891 YYPVSSAQKRLYILNHLEGGELSYNMLGLMTVKGELDRDKLQQAFDKLIHRHESLRTGFK 3950 Query: 72 LDADSGMLRQKINPAVSFAFPVYELSETETVLLIQDFVRPFRLDKPPLFRTALIRLTDRE 131 + G Q + V FA Y E E I FVR F+L++PPL R LI L Sbjct: 3951 MV--DGEPVQYVLDHVEFAVESYYAKEDEIDHCISQFVRAFQLEEPPLLRVGLIELQPNH 4008 Query: 132 ETVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSLLAGTEQWNRQ 191 +L+ DMHHII+DGTS+++L+K+ Y+ EL L++QYKDY+V Q+ A EQ +Q Sbjct: 4009 -AILMFDMHHIISDGTSMNVLIKEFVRAYQGAELPPLRIQYKDYSVWQTGEARLEQIQKQ 4067 Query: 192 EEYWLGVFHEPVPALPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTESTLFMV 251 E+YWL ++ +P L + T +F IDE+ + L +LA TESTL+MV Sbjct: 4068 EDYWLELYSGDIPVLHLPTDYIRPSTRDFTGATLHFTIDEKKSEGLKQLALKTESTLYMV 4127 Query: 252 LMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFFACRKLSFQEYLY 311 L+A++T LLSK S EDIVVG P +GR H LD+I+GM VNTLA+R + ++ +F +YL Sbjct: 4128 LLASYTLLLSKYSGQEDIVVGSPIAGRPHADLDSIIGMFVNTLAMRNYPAKEKTFSQYLA 4187 Query: 312 QVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAAE-QIDAIDMVSF 370 +VK+ ++AYE+QDYP + LV++LN + +L PLF+ MF E + +D + + Sbjct: 4188 EVKENALKAYEHQDYPFEALVDQLNIARDLSRNPLFDTMFVLQNTEQEQLGMDGLTFKPY 4247 Query: 371 GHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQVITSNLETGL 430 KFDL V+E + + + Y +LF E + ++ F+++I I + E L Sbjct: 4248 PSKHTMAKFDLTLTAVEEETHIHCTMEYLTTLFKPETVERMMRHFVQLIDAIIEHPEARL 4307 Query: 431 GDL 433 L Sbjct: 4308 ASL 4310 Score = 281 bits (718), Expect = 3e-74, Method: Compositional matrix adjust. Identities = 151/416 (36%), Positives = 236/416 (56%), Gaps = 8/416 (1%) Query: 13 YPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTTIEL 72 YP S Q+ ++++ ++ G +YN+P I ++G +D RL+ A +L+ RHESLRT E+ Sbjct: 4931 YPVSSVQKMVYLSTQIEGGELSYNMPGILTLEGRIDMDRLQTAFHRLIQRHESLRTGFEM 4990 Query: 73 DADSGMLRQKINPAVSFAFPVYELSETETVLLIQDFVRPFRLDKPPLFRTALIRLTDREE 132 M Q + P V F Y+ + E L + FVRPF L + PL R LI L ++E+ Sbjct: 4991 IRGEPM--QMVKPEVEFTIERYKATAEEVEELFRTFVRPFDLSQAPLLRVGLIEL-EQEK 5047 Query: 133 TVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSLLAGTEQWNRQE 192 + + DMHHI+TDG S++I +++L LY+ +EL L++QYKD+ Q E+ +QE Sbjct: 5048 HIFMFDMHHIVTDGASMNIFIEELIQLYDGKELAPLRIQYKDFTAWQQQAEQKERIKKQE 5107 Query: 193 EYWLGVFHEPVPA--LPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTESTLFM 250 +YWL VFHE +P+ LP D + R+ E + F ++E + +L + T ST +M Sbjct: 5108 DYWLDVFHEALPSFELPKDFARPQVRSFE--GKRYNFVLNESVVQGVKQLEELTGSTTYM 5165 Query: 251 VLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFFACRKLSFQEYL 310 +L AA+T LL+K S EDIVVG P +GR H+ L +I+GM VNTLA+R + +F++Y+ Sbjct: 5166 ILFAAYTILLAKYSGQEDIVVGTPVAGRVHDDLQHIIGMFVNTLAIRTAPAGEKTFKDYV 5225 Query: 311 YQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAAE-QIDAIDMVS 369 + K+ +++AYENQ+YP + LVEKL +L PLF+ MF E + +ID++ + Sbjct: 5226 TETKETMLKAYENQEYPFEELVEKLGVQRDLSRNPLFDTMFVLQNTEQTDIEIDSLAVRP 5285 Query: 370 FGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQVITSN 425 + KFDL + Y LF + I L ++ I+ + N Sbjct: 5286 YEETHAVAKFDLQLTFEMHQHEIQGSFDYCTKLFKKRTIATLAQDYVMILSAVIQN 5341 Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 97/426 (22%), Positives = 172/426 (40%), Gaps = 29/426 (6%) Query: 10 ETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTT 69 E YP +P Q+ + L +Y ++G L R E +L L ++ LRT Sbjct: 2827 ENVYPLTPMQKGMLFHSLLDEDSNSYFEQASFDLQGELKIDRFEASLDHLFAKYAVLRTR 2886 Query: 70 IELDADSGMLR-----QKINPAVSFAFPVYELSETETVLLIQ--DFVRPFRLDKPPLFRT 122 + L+ Q++ + + E + + Q D + F L + PL R Sbjct: 2887 FYSGWNDIPLQIVYKTQRMKVHFTDLRDIDENQRKDEIASYQSEDKAKGFDLARDPLMRI 2946 Query: 123 ALIRLTDREETVLIIDMHHIITDGTSVSILLKD----LAALYENRELEVLKLQYKDYAVR 178 A+ R+ +R+ LI HHI+ DG + ++ K+ L E RE + L Y D + Sbjct: 2947 AIFRIEERKYH-LIWSFHHIVMDGWCLPLITKEAFEHYIGLQEGRETD---LAYTDPYSK 3002 Query: 179 QSLLAGTEQWNRQEEYWLGVFHEPVPALPWDGRGTEHRAGEDPSRTAY----FAIDEQTA 234 + N + YW E + + R R + AY +++ Sbjct: 3003 YIEWLDQQDQNAAKRYW----REYLEGYKGETRILHKRPQHERKAYAYANEICRFNQKQT 3058 Query: 235 CALHRLAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHE--GLDNIVGMLVN 292 L R+A TL ++ + LL K S D+V G SGR E G++ ++G+ +N Sbjct: 3059 RQLQRIANQHHVTLNTLIQTLWGILLQKYSGTGDVVFGSVVSGRPAEISGVEQMIGLFIN 3118 Query: 293 TLAVRFFACRKLSFQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQ 352 T+ VR SF E + V+D + + YPL + + NL L + Sbjct: 3119 TIPVRICCDEGSSFVETMKMVQDNALASQSYDTYPLYEIQAQTEQKQNLIDHILIFENYP 3178 Query: 353 FA-EMEAAEQIDAIDMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGEL 411 ++E +++++F H +D + +V+ L + Y ++++ + + E Sbjct: 3179 IGQQVEEGHNAAELNIMNF-HMEEHSHYDFNMVVI-PGEQLNVHFGYNQNVYEQSEV-ER 3235 Query: 412 ISGFIE 417 ISG E Sbjct: 3236 ISGHFE 3241 Score = 76.6 bits (187), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 80/340 (23%), Positives = 138/340 (40%), Gaps = 34/340 (10%) Query: 10 ETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTT 69 E YP +P Q+ + AY + + G LD ++L L R+E RT Sbjct: 1316 ENIYPLTPMQKGMLFHSLFDSHSGAYFQQTMFELHGDLDIDSFSKSLDDLSKRYEIFRTN 1375 Query: 70 IELDADSGMLRQKINPAVSFAFPVYELSETE--------TVLLIQDFVRPFRLDKPPLFR 121 D + Q I F +L E + +D +R F L K L R Sbjct: 1376 FLKGKDQPL--QIIFKTKKIGFQFIDLREMDQARQDDRICAYAKEDKLRGFDLAKDVLMR 1433 Query: 122 TALIRLTDREETVLIIDMHHIITDGTSVSILLKDL----AALYENRELEVLKL----QYK 173 ++R TD I HHI+ DG + ++ K++ AL + ++ E + QY Sbjct: 1434 VIVLR-TDDTTYRFIWSFHHILMDGWCLPLITKEIFDHYFALLQQKQPEQAAITPYSQYI 1492 Query: 174 DYAVRQSLLAGTEQWNRQEEYWLGVFHEPVPALPWDGRGTEHRAGED---PSRTAYFAID 230 ++ RQ W++ +L + E L H+A ++ P + + AID Sbjct: 1493 EWLDRQDAEEAKRYWDQ----YLEGYEEQTVLL-----KDSHQAEDEHYFPEKVS-CAID 1542 Query: 231 EQTACALHRLAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHE--GLDNIVG 288 + + A TL +L A+ LL K + D+V G SGR ++ ++G Sbjct: 1543 TDLTLKMKQTASKHHVTLNTLLQTAWGILLQKYNRSRDVVFGSVVSGRPSAIPNVETMIG 1602 Query: 289 MLVNTLAVRFFACRKLSFQEYLYQVKDKLIEAYENQDYPL 328 + +NT+ VR +F E + + +++ + + + YPL Sbjct: 1603 LFINTIPVRIQCEAGTTFAELMKRTQERAVASQTYETYPL 1642 Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 50/242 (20%), Positives = 113/242 (46%), Gaps = 26/242 (10%) Query: 188 WNRQEEYWLGVFHEP-----VPALPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQ 242 + Q YW +F E +P + R G ++ Y ++ + + + +A Sbjct: 4 FKNQVTYWANLFDEEDSLSVIPYFKTAENASLTRVGYQ-EKSIYRSLSPEVSQRILTMAN 62 Query: 243 TTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLD--NIVGMLVNTLAVRFFA 300 +E +++L+A LL K +D ++G+PT + N + +L NTL+ Sbjct: 63 HSEMATYLILLAGIECLLYKYTDRASTILGIPTVSKQKSSSSTVNTIVLLKNTLS----- 117 Query: 301 CRKLSFQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAAE 360 C+ +F+ Q+K + ++ +NQ+ P ++V+ +N ++ + PL + + E+ + + Sbjct: 118 CQS-TFKTVFEQLKKAVNDSLKNQNLPFRKIVQHVNVQYDNENIPLIHTVVSLNEIHSLQ 176 Query: 361 QIDAIDMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQ 420 + I + H FDL E+S + +++ Y +L+ E+ + +++S +++ Sbjct: 177 FKEDIATDTLFH------FDL------ENSEIHLKLIYNGNLYDEDYMDQMVSHLNQLLS 224 Query: 421 VI 422 VI Sbjct: 225 VI 226 >dbj|BAB69699.1| iturin A synthetase B [Bacillus subtilis] Length = 5362 Score = 295 bits (755), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 162/423 (38%), Positives = 252/423 (59%), Gaps = 4/423 (0%) Query: 12 YYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTTIE 71 YYP S AQ+ +++ + L G +YN+ + ++G LD +L++A + L+ RHESLRT + Sbjct: 3886 YYPVSSAQKRLYILNHLEGGELSYNMLGLMTVEGKLDRDKLQQAFRTLILRHESLRTGFK 3945 Query: 72 LDADSGMLRQKINPAVSFAFPVYELSETETVLLIQDFVRPFRLDKPPLFRTALIRLTDRE 131 + AD ++ ++ A +F Y+ E + L I+ F+RPF LD+PPL R LI L + Sbjct: 3946 M-ADGEPVQYVLDHA-AFEAEWYQGEEDDADLYIRQFIRPFHLDEPPLLRVGLIELQP-D 4002 Query: 132 ETVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSLLAGTEQWNRQ 191 +L+ DMHHII+DGTS+S+L+K+ +YE L L++QYKDYAV Q+ A +Q +Q Sbjct: 4003 RGILMFDMHHIISDGTSMSVLIKEFIRIYEGETLPPLRIQYKDYAVWQTSEARLQQIQKQ 4062 Query: 192 EEYWLGVFHEPVPALPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTESTLFMV 251 E YWL ++ VP L A + T +F +D+Q + L +LA TESTL+MV Sbjct: 4063 EAYWLELYSGDVPVLHLPADYIRPSARDFAGATMHFTLDKQKSDGLKQLASQTESTLYMV 4122 Query: 252 LMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFFACRKLSFQEYLY 311 L+A++T LLSK S EDI+VG P +GR H L+ I+GM VNTLA+R + + +F +YL Sbjct: 4123 LLASYTLLLSKYSGQEDIIVGSPIAGRPHADLEPIIGMFVNTLAMRNYPEKGKTFSQYLS 4182 Query: 312 QVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAAE-QIDAIDMVSF 370 +VK+ ++AYE+QDYP + L+++LN + +L PLF+ MF E + +I+ + + Sbjct: 4183 EVKENALKAYEHQDYPFEALIDQLNIARDLSRNPLFDTMFVLQNTEQEQLEINDVTFKPY 4242 Query: 371 GHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQVITSNLETGL 430 + KFDL V+E +S+ + Y +LF E I ++ F +++ I E L Sbjct: 4243 PNGHTMAKFDLTLTAVEEGASIQFTLEYLTALFKPETIERMMGHFEQLVDSIIKQPEAEL 4302 Query: 431 GDL 433 L Sbjct: 4303 ARL 4305 Score = 264 bits (675), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 148/429 (34%), Positives = 240/429 (55%), Gaps = 8/429 (1%) Query: 8 KQETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLR 67 K + YP S Q+ ++++ ++ G +YN+P I ++G LD RL+ A ++L+ RHESLR Sbjct: 4919 KAKDVYPVSSVQKMVYLSTQIEGGELSYNMPGILTLEGKLDMNRLQTAFQRLIQRHESLR 4978 Query: 68 TTIELDADSGMLRQKINPAVSFAFPVYELSETETVLLIQDFVRPFRLDKPPLFRTALIRL 127 T E+ G Q I V F+ Y+ + E + FVRPF L + PL R LI L Sbjct: 4979 TGFEMV--RGEPVQVIKSQVEFSMERYKATADEVEECFRTFVRPFDLSQAPLLRAGLIEL 5036 Query: 128 TDREETVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSLLAGTEQ 187 +++ + + DMHHIITDG S++I +++L LY+ +EL L++QYKD+ + E+ Sbjct: 5037 -EQDLHIFMFDMHHIITDGASMNIFVEELIQLYDGKELAPLRIQYKDFTEWKHQKEQRER 5095 Query: 188 WNRQEEYWLGVFHEPVPA--LPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTE 245 QEEYWLGVFHE +P+ LP D R+ + + F +D+ + +L + T Sbjct: 5096 IKSQEEYWLGVFHEELPSFELPKDFARPPVRSFD--GKRHNFTLDKTVTQGIKQLEELTG 5153 Query: 246 STLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFFACRKLS 305 +T +M+L +A++ LL+K S +DIVVG P +GR H L+ I+GM VNTLA+R + + Sbjct: 5154 TTAYMILFSAYSILLAKYSGQDDIVVGTPIAGRPHADLEPIIGMFVNTLAIRTAPMAEKT 5213 Query: 306 FQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAAE-QIDA 364 F +Y+ + K+ +++A+E+Q+YP + LVEKL +L PLF+ MF E + ++D+ Sbjct: 5214 FLDYITETKETMLKAFEHQEYPFEELVEKLGVKRDLSRNPLFDTMFVLQNTEQTDIEVDS 5273 Query: 365 IDMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQVITS 424 + + + KFDL + + + Y LF ++ I L ++ I+ I Sbjct: 5274 LAVRPYEQTETAAKFDLQLNFLIDQDEIQGSFDYCTKLFKKKTIAVLAKDYVMILSAIMR 5333 Query: 425 NLETGLGDL 433 N L D+ Sbjct: 5334 NPSIPLKDI 5342 Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 97/445 (21%), Positives = 180/445 (40%), Gaps = 33/445 (7%) Query: 10 ETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTT 69 E YP +P Q+ + L ++Y ++G L + +L++L + LRT Sbjct: 2825 ENVYPLTPMQKGMLFHSLLDEASSSYFEQASFDLQGELKIDWFKASLERLFETYAVLRTR 2884 Query: 70 IEL---DADSGMLRQKINPAVSFA--FPVYELSETETVLLIQ--DFVRPFRLDKPPLFRT 122 D ++ + P + FA + E + + Q D + F L + PL R Sbjct: 2885 FYSGWNDTPLQIVYKTQTPQIHFADLRDIEEHLREDAIAAYQREDKAKGFDLARDPLMRI 2944 Query: 123 ALIRLTDREETVLIIDMHHIITDGTSVSILLKDL----AALYENRELEVLK-LQYKDYAV 177 A+ R+ DR+ LI HHI+ DG +S++ K++ +AL E RE E L + Y DY Sbjct: 2945 AIFRMEDRKYH-LIWSFHHIVMDGWCLSLITKEVFDHYSALQEGREPEPLSAVPYSDY-- 3001 Query: 178 RQSLLAGTEQWNRQEE-----YWLGVFHEPVPALPWDGRGTEHRAGEDPSRTAYFAIDEQ 232 E +RQ++ YW G + +H E D + Sbjct: 3002 -------IEWLDRQDQGAAKRYWGGYLEGYKGETTLLHKIAQHEQKEYAYANLICRFDHE 3054 Query: 233 TACALHRLAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHE--GLDNIVGML 290 L ++A + TL ++ + LL K S D+V G SGR E ++ ++G+ Sbjct: 3055 QTKQLQQIANQHQVTLNTLIQTLWGVLLQKYSGSADVVFGSVVSGRPAEIPDVEQMIGLF 3114 Query: 291 VNTLAVRFFACRKLSFQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVM 350 +NT+ VR +F + + V+ + + YPL + + NL + Sbjct: 3115 INTIPVRIRCDEDSTFADTMQMVQQNALASQSYDTYPLYEIQAQTEQKQNLIDHIMIFEN 3174 Query: 351 FQFAEM--EAAEQIDAIDMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAI 408 + + E +++ +F H +DL+ +V+ L + + ++ + + + Sbjct: 3175 YPIGQQAEETGHHGTELNITNF-HMQEHSHYDLNVVVI-PGKQLAVHFGFNKNEYEKSEV 3232 Query: 409 GELISGFIEIIQVITSNLETGLGDL 433 L F +++Q + + DL Sbjct: 3233 ERLRGHFEKLMQQVLRQPSVKIEDL 3257 Score = 80.5 bits (197), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 84/341 (24%), Positives = 145/341 (42%), Gaps = 35/341 (10%) Query: 10 ETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTT 69 E YP +P Q+ + AY + + G L+ ++L L +++ RT Sbjct: 1316 ENIYPLTPMQKGMLFHSLFDPNSGAYFQQTMFDLHGDLEIDSFSKSLDGLSQKYDIFRTN 1375 Query: 70 IELDADSGMLRQKIN-PAVSFAF-PVYELSETETVLLIQ-----DFVRPFRLDKPPLFRT 122 L+ + F F + E+ E++ +IQ D +R F L+K L R Sbjct: 1376 FYRGWKDQPLQIIFKTKKIGFQFNDLREMKESQKEAMIQQYAREDKMRGFDLEKGALMRL 1435 Query: 123 ALIRLTDREETVLIIDMHHIITDGTSVSILLKDLA----ALYENRELEVLKL----QYKD 174 ++R TD + I HHI+ DG + ++ K++ AL + ++ E + QY + Sbjct: 1436 FILR-TDEKTYRFIWSFHHILMDGWCLPLITKEIFENYFALLQQKQPEQSSITPYSQYIE 1494 Query: 175 YAVRQSLLAGTEQWNRQEEYWLGVFHEPVPALPWDGRGTEHRAGED----PSRTAYFAID 230 + RQ T W+ +Y G +E LP D H A ED P + I Sbjct: 1495 WLGRQDAKEATAYWD---QYLEG--YEEQTGLPKD-----HHAAEDGRYVPEKVT-CDIS 1543 Query: 231 EQTACALHRLAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNI---V 287 + R A TL +L A+ LL K + D+V G SGR G+ N+ + Sbjct: 1544 SDLTSKMKRTAGKHHVTLNTLLQTAWAVLLQKYNRSRDVVFGSVVSGR-PAGIPNVETMI 1602 Query: 288 GMLVNTLAVRFFACRKLSFQEYLYQVKDKLIEAYENQDYPL 328 G+ +NT+ VRF +F + + +++ + + + + +PL Sbjct: 1603 GLFINTIPVRFRCEAGTTFAGLMKEAQERAVASQQFETHPL 1643 Score = 64.3 bits (155), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 75/300 (25%), Positives = 125/300 (41%), Gaps = 21/300 (7%) Query: 35 YNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTTIELDADSGMLRQKINPAVS--FAFP 92 YN V+ +L + L+KL H++LR T ++G Q A S + Sbjct: 2382 YNQAVMLHAPEGFQETQLRQTLQKLAEHHDALRMTFRT-TENGCEAQNEEIAQSGLYRLE 2440 Query: 93 VYELSETE----TVLLIQDFVRP-FRLDKPPLFRTALIRLTDREETVLIIDMHHIITDGT 147 V L E T+ D ++ RL PL + L + + + L+I +HH+I DG Sbjct: 2441 VLNLKEDSDPGRTIEAKADEIQSSMRLSDGPLMKAGLFQCANGDH--LLIAIHHLIIDGI 2498 Query: 148 SVSILLKDLAALYENRE-LEVLKLQYKD-----YAVRQSLLAGTEQWNRQEEYWLGVFHE 201 S ILL+D+ + Y+ E + V++L K +A R S A +E +++EYW + Sbjct: 2499 SWRILLEDIVSGYKQAENVRVIQLPQKTDSFQLWAKRLSEYAQSETIKQEQEYWTKIEQT 2558 Query: 202 PVPALPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTESTLFMVLMAAFTALLS 261 V LP D T H +D E+T L + + + + +L+ + +S Sbjct: 2559 EVKPLPKDFHET-HTTAKDSETATVEWTKEETELLLKQANRAYHTEINDLLLTSLGLSIS 2617 Query: 262 KLSDCEDIVVGMPTSGRHH--EGLD--NIVGMLVNTLAVRFFACRKLSFQEYLYQVKDKL 317 S E I + + GR + +D VG + V A +Y+ K+ L Sbjct: 2618 HWSGLEQIPIHLEGHGREQIIQDIDISRTVGWFTSLYPVVLHAQPGKEISDYIKTTKEGL 2677 Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 55/245 (22%), Positives = 118/245 (48%), Gaps = 38/245 (15%) Query: 191 QEEYWLGVFHEP--VPALPWDGRGTEHRAGEDPS--RTAY------FAIDEQTACALHRL 240 QE YW +F E + A P+ +A + S RT Y ++ + + + + Sbjct: 7 QETYWENLFDEEDGLSAFPY------FKAADKASLARTGYQEKCICRSLSPEVSQRIMTM 60 Query: 241 AQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEG---LDNIVGMLVNTLAVR 297 A ++ +++L+A LL K +D +++G+PT + G ++NIV +L NTL+ Sbjct: 61 ANHSDMAAYLILLAGIECLLYKYTDRTSLILGIPTVSKQKAGQSAVNNIV-LLKNTLS-- 117 Query: 298 FFACRKLSFQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEME 357 + +F+ Q+K+ + ++ +NQ+ P ++V L+ +N + PL + + E+ Sbjct: 118 ----NESTFKTVFGQLKEAVNDSLKNQNLPFRKMVRHLSVQYNDEHMPLIHTVVSLNEIH 173 Query: 358 AAEQIDAIDMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIE 417 + + + + H FDL E++ + +++ Y +L+ E I +++S + Sbjct: 174 SKQCKEDTATDTLFH------FDL------ENNGIHLKLFYNGNLYDERYINQIVSHLDQ 221 Query: 418 IIQVI 422 ++ VI Sbjct: 222 LLSVI 226 >sp|O68008|BACC_BACLI Bacitracin synthetase 3 (BA3) [Includes: ATP-dependent isoleucine adenylase (IleA) (Isoleucine activase); ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); ATP-dependent histidine adenylase (HisA) (Histidine activase); ATP-dependent D-aspartate adenylase (D-AspA) (D-aspartate activase); ATP-dependent asparagine adenylase (AsnA) (Asparagine activase); Aspartate racemase ; Phenylalanine racemase [ATP hydrolyzing] ] pir||T31679 bacitracin synthetase 3 - Bacillus licheniformis gb|AAC06348.1| bacitracin synthetase 3; BacC [Bacillus licheniformis] Length = 6359 Score = 290 bits (741), Expect = 7e-77, Method: Compositional matrix adjust. Identities = 160/427 (37%), Positives = 247/427 (57%), Gaps = 10/427 (2%) Query: 8 KQETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLR 67 +++ YY S AQ+ +++ D++ G G +YN+P ++KG D R E ALK ++ RHE+LR Sbjct: 1047 EEKEYYRLSSAQKRLYILDQIEGSGLSYNIPFTMKVKGRFDIRRFENALKTIIQRHEALR 1106 Query: 68 TTIELDADSGMLRQKINPAVSFAFPVYELSETETVLLIQDFVRPFRLDKPPLFRTALIRL 127 T+ L AD G QKI V F+ ++ +I+ FVRPF L K PLFRT ++++ Sbjct: 1107 TSF-LMAD-GEPVQKIEKEVDFSIKCSKIQSLSIQEIIKQFVRPFDLKKAPLFRTEVVKV 1164 Query: 128 TDREETVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSLLAGTEQ 187 D EE +++ DMHHII+DG S+ +L K++ LY +EL+ L LQYKDY+ Q ++ Sbjct: 1165 DD-EEHIILFDMHHIISDGASMGVLTKEICDLYGGKELKPLSLQYKDYSEWQRDFYQKDE 1223 Query: 188 WNRQEEYWLGVFHEPVPAL--PWD-GRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTT 244 RQ+EYWL +F +P L P D R H D R FAID + L R+A+ Sbjct: 1224 MKRQKEYWLNIFKGEIPVLNMPTDYPRPQMHSVEGD--RIG-FAIDGELTKKLKRIAKDN 1280 Query: 245 ESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFFACRKL 304 +T++M+L+AA+T LL S ED+++G P GR H L +++GM VNTLA+R Sbjct: 1281 GATMYMLLLAAYTVLLRTYSGQEDVIIGTPIQGRKHHELKHVIGMFVNTLAMRNHPKGDK 1340 Query: 305 SFQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAAE-QID 363 +F EYL VK+ ++AYENQDY D LVE+L+ ++ PLF+ MF +E A+ +I+ Sbjct: 1341 TFAEYLQDVKETALKAYENQDYQFDDLVEQLDLERDMSRNPLFDTMFVLQNLEKADAEIE 1400 Query: 364 AIDMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQVIT 423 + F D KFDL +++ S + ++ Y LF E + + + F+ +++ I+ Sbjct: 1401 GLTFEPFESDIHISKFDLTLSAIEKDSKIEFDLEYCTKLFKRETVERMAAHFVRVLEDIS 1460 Query: 424 SNLETGL 430 + L Sbjct: 1461 KRTDKRL 1467 Score = 274 bits (701), Expect = 3e-72, Method: Compositional matrix adjust. Identities = 154/435 (35%), Positives = 241/435 (55%), Gaps = 10/435 (2%) Query: 2 LSGAERKQETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVN 61 ++ AE K+ YY S AQR +++ +++ G +YN+P +I G D R E+A ++L+ Sbjct: 3579 ITQAEEKE--YYALSSAQRRLYILNQIEPGGLSYNMPFAMKIAGDFDVDRFEDAFRQLIE 3636 Query: 62 RHESLRTTIELDADSGMLRQKINPAVSFAFPVYELSETETVLLIQDFVRPFRLDKPPLFR 121 RHE+LRT + G QKI V F L + I+ F++PF L+K PL R Sbjct: 3637 RHEALRTAFVMV--DGEPVQKIEKEVDFKVKYGRLGQDPLEEKIKAFIKPFALEKAPLLR 3694 Query: 122 TALIRLTDREETVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSL 181 +++ + +E VL++DMHHII+DG S++I ++LA LYE + L L +QYKD++ Q L Sbjct: 3695 AEVLKASG-DEHVLMLDMHHIISDGVSMAIFTRELAELYEGKTLPPLTIQYKDFSEWQKL 3753 Query: 182 LAGTEQWNRQEEYWLGVFHEPVPAL--PWDGRGTEHRAGEDPSRTAYFAIDEQTACALHR 239 ++ RQE+YWL VF VP L P D + + R+ E F ID +T+ L++ Sbjct: 3754 FYQKDEVKRQEDYWLNVFQGEVPVLNLPADEKRPQKRSIE--GDIVQFEIDGETSAMLNK 3811 Query: 240 LAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFF 299 LA+ +T++M+L+A +T LL+K + EDIVVG P +GRHH L +++G+ +NTLA+R Sbjct: 3812 LAKENGATMYMLLLAGYTTLLAKYTGQEDIVVGSPIAGRHHSDLKHVIGLFINTLAMRNH 3871 Query: 300 ACRKLSFQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAA 359 + F +YL +VK+ ++AYENQDYP D LVEKL+ ++ PLF+ M + Sbjct: 3872 PKGDMPFADYLKEVKETALKAYENQDYPFDELVEKLDVKRDMSRHPLFDTMLVLQNFDGD 3931 Query: 360 E-QIDAIDMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEI 418 E ID + + KFDL + + + Y LF I + I I Sbjct: 3932 EADIDGLTFQPLQTEVNISKFDLTLTAAETNEGIQCVFNYSTKLFKRSTIERMAGHLINI 3991 Query: 419 IQVITSNLETGLGDL 433 ++ ++ L D+ Sbjct: 3992 LKEAANDPHMPLSDV 4006 Score = 88.2 bits (217), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 89/341 (26%), Positives = 148/341 (43%), Gaps = 35/341 (10%) Query: 10 ETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTT 69 E YP + QR + AY + +KG++D E ++ RHE LR + Sbjct: 5089 EKIYPLANMQRGMLFHALEDKESQAYFEQMAINMKGLIDERLFAETFNDIMERHEILRAS 5148 Query: 70 IELDADSGMLRQKINPAVSFAFPVYEL---SETETVLLIQ-----DFVRPFRLDKPPLFR 121 IE + + R I ++L S E +IQ D + FRL+ PL R Sbjct: 5149 IEYEI-TDEPRNVIIKDRKINLDYHDLRKQSPAEREQVIQAYRKADREKGFRLNSEPLIR 5207 Query: 122 TALIRLTDREETVLIIDMHHIITDGTSVSILLKDLAALYENREL-EVLKLQ----YKDYA 176 AL+R D T + + HHI+ DG S I++ +L +Y +E + +L+ Y DY Sbjct: 5208 AALMRTEDDSYTFIWTN-HHILLDGWSRGIIMGELFHMYHMKEARQKHRLEEARPYSDY- 5265 Query: 177 VRQSLLAGTEQWNRQ--EEYW---LGVFHE--PVPALPWDGRGTEHRAGEDPSRTAYFAI 229 + +Q +++ + YW L F E P+ L +++ E A Sbjct: 5266 -----IGWLQQQDKEAAKAYWRNYLSGFTEKSPISVLAGSSGHAKYKRKE-----AVIEF 5315 Query: 230 DEQTACALHRLAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHE--GLDNIV 287 EQ + LA T VL + LL++ + +D+V G SGR + G++ +V Sbjct: 5316 PEQLTGRITELASRNNVTFHTVLQCIWGMLLARYNQTDDVVFGTVISGRDAQVTGIEKMV 5375 Query: 288 GMLVNTLAVRFFACRKLSFQEYLYQVKDKLIEAYENQDYPL 328 G+ +NT+ R + SF+E + V+++ +E D L Sbjct: 5376 GLFINTVPTRIRLDKSQSFKELIKSVQEQALEGRTYHDMNL 5416 Score = 86.7 bits (213), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 87/335 (25%), Positives = 148/335 (44%), Gaps = 39/335 (11%) Query: 8 KQETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLR 67 K E YP S Q+ + AY I +KG +D EE+L +++ RHE LR Sbjct: 4 KVEKIYPLSNMQKGMLFHAMKDEASHAYFEQFIIELKGDVDERMFEESLNEVMKRHEILR 63 Query: 68 TTIELDADSGMLRQKINPAVSFAF-PVYELSETETVL---LIQDFVRPFRLDKPPLFRTA 123 + D + + + F + + + + VL L +D + F L K L R Sbjct: 64 ASFHHRLDEPLHVIIKDRHMKFDYLDIRGRHDQDGVLERYLAEDRQKGFDLAKDTLMRAC 123 Query: 124 LIRLTDREETVLIIDMHHIITDGTSVSILLKDLAALYE------NRELEVLKLQYKDYAV 177 LIR++D + + HHI+ DG + I+L +L +YE N +LE + Y DY Sbjct: 124 LIRMSD-DSYQFVWTYHHILLDGWCLGIILDELLTIYEMKRKGQNHQLEDPR-PYSDY-- 179 Query: 178 RQSLLAGTEQWNRQE--EYWLGVF--HEPVPALPWDGRGTEHRAGEDPSRTAYFAIDEQT 233 + E +++E YW ++ +LP PS T + ++ Sbjct: 180 ----IKWLEDQDKEEAQSYWESYLSGYDQKNSLP---------KLRTPSETGFKRREKTI 226 Query: 234 ACA------LHRLAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHH--EGLDN 285 C+ L +LA T+ VL + + +L+K ++ ED+V G SGR EG++ Sbjct: 227 ECSKELTNRLIKLANRNHVTINTVLQSIWGVILAKYNNSEDVVFGTVVSGRDAEVEGIET 286 Query: 286 IVGMLVNTLAVRFFACRKLSFQEYLYQVKDKLIEA 320 +VG+ +NT+ R + F++ L Q + +E+ Sbjct: 287 MVGVFINTIPTRIRLDKDKLFKDVLRQTQADALES 321 Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 82/329 (24%), Positives = 143/329 (43%), Gaps = 27/329 (8%) Query: 10 ETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTT 69 E YP + Q+ + AY + I+G +D LE + ++ RHE LR + Sbjct: 2542 EKIYPLANMQKGMLFHAIEDHTSDAYFQQTVMDIEGYVDPAILEASFNDIMKRHEILRAS 2601 Query: 70 IELDADSGMLRQKINPAVSFAFPVYELSETETV--------LLIQDFVRPFRLDKPPLFR 121 E + RQ I S F + ++++ LL +D + F L K L R Sbjct: 2602 YEYEIVEEP-RQIIIENRSIDFTYFNIAKSSAQQQEMFIERLLNEDRKKGFDLSKDVLMR 2660 Query: 122 TALIRLTDREETVLIIDMHHIITDGTSVSILLKDLAALYENR---ELEVLK--LQYKDYA 176 L++ +R L+ HHI+ DG + I++++L +YENR + LK Y DY Sbjct: 2661 AYLLKTAERSYR-LVWSHHHILLDGWCLGIIMRELFVIYENRMNGKASPLKETKPYSDYI 2719 Query: 177 V---RQSLLAGTEQWNRQEEYWLGVFHEPVPALPWDGRGTEHRAGEDPSRTAYFAIDEQT 233 RQ + W EY G +E LP + ++ R + +Q Sbjct: 2720 KWLERQDQEEARQYW---REYLKG--YEEQAQLPTLTK--RKKSSRYDRREKVIHLSKQL 2772 Query: 234 ACALHRLAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHH--EGLDNIVGMLV 291 L LA TL V+ + +L++ + +D+V G SGR +G+++++G+ + Sbjct: 2773 TKQLKELAAKNSVTLHTVIQTIWGLMLTRYTKIDDVVFGTVVSGREANVDGIEDMIGLFI 2832 Query: 292 NTLAVRFFACRKLSFQEYLYQVKDKLIEA 320 NT+ R + F + L +V++ I++ Sbjct: 2833 NTIPTRIRFNEQARFNDCLQKVQEDAIQS 2861 >pir||JX0340 gramicidin S synthase 2 - Bacillus brevis dbj|BAA06146.1| gramicidin S synthetase 2 [Brevibacillus brevis] Length = 4450 Score = 288 bits (736), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 163/431 (37%), Positives = 251/431 (58%), Gaps = 14/431 (3%) Query: 10 ETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTT 69 + YYP S AQ+ +F+ ++ G G +YN+P I I+G L+ RLE A K+L+ RHESLRT+ Sbjct: 3139 QDYYPVSSAQKRMFIVNQFDGVGISYNMPSIMLIEGKLERTRLESAFKRLIERHESLRTS 3198 Query: 70 IELDADSGMLRQKINPAVSFAFPVYELSETETV-LLIQDFVRPFRLDKPPLFRTALIRLT 128 E+ +G QKI+ F Y+++ E V +I +F++PF L PL R L++L Sbjct: 3199 FEII--NGKPVQKIHEEADFNMS-YQVASNEQVEKMIDEFIQPFDLSVAPLLRVELLKL- 3254 Query: 129 DREETVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSLLAGTEQW 188 + + VLI DMHHII+DG S +IL+K+L LY+ L L++QYKD+AV Q+ +E + Sbjct: 3255 EEDRHVLIFDMHHIISDGISSNILMKELGELYQGNALPELRIQYKDFAVWQNEWFQSEAF 3314 Query: 189 NRQEEYWLGVFHE--PVPALPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTES 246 +QEEYW+ VF + P+ +P D ++ + T F +Q L+R+A T + Sbjct: 3315 KKQEEYWVNVFADERPILDIPTDYPRPMQQSFDGAQLT--FGTGKQLMDGLYRVATETGT 3372 Query: 247 TLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFFACRKLSF 306 TL+MVL+AA+ LLSK S EDI+VG P GR H L+NIVGM VNTLA+R + +F Sbjct: 3373 TLYMVLLAAYNVLLSKYSGQEDIIVGTPIVGRSHTDLENIVGMFVNTLAMRNKPEGEKTF 3432 Query: 307 QEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAAEQIDAID 366 + ++ ++K + A+ENQDYP + L+EKL +L PLF+ +F + E + + Sbjct: 3433 KAFVSEIKQNALAAFENQDYPFEELIEKLEIQRDLSRNPLFDTLFSLQNI-GEESFELAE 3491 Query: 367 MVSFGHDSVP----GKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQVI 422 + D V KFDL + V++ + + Y L+ E+ + +L FI+I++ I Sbjct: 3492 LTCKPFDLVSKLEHAKFDLSLVAVEKEEEIAFGLQYCTKLYKEKTVEQLAQHFIQIVKAI 3551 Query: 423 TSNLETGLGDL 433 N + L D+ Sbjct: 3552 VENPDVKLSDI 3562 Score = 276 bits (706), Expect = 7e-73, Method: Compositional matrix adjust. Identities = 158/428 (36%), Positives = 242/428 (56%), Gaps = 9/428 (2%) Query: 10 ETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTT 69 + YYP S AQ+ +++ + G G YNVP + I+G LD R E A+K L+NRHE+LRT+ Sbjct: 2094 QDYYPVSSAQKRMYILYEFEGAGITYNVPNVMFIEGKLDYQRFEYAIKSLINRHEALRTS 2153 Query: 70 IELDADSGMLRQKINPAVSFAFPVYELSETETVLLIQDFVRPFRLDKPPLFRTALIRL-T 128 + +G Q+++ V E E E +++ FV+PF L+ P R L++L + Sbjct: 2154 FY--SLNGEPVQRVHQNVELQIAYSEAKEDEIEQIVESFVQPFDLEIAPALRVGLVKLAS 2211 Query: 129 DREETVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSLLAGTEQW 188 DR + ++DMHHII+DG S+ I+ K++A LY+ +EL L +QYKD+AV Q+ + Sbjct: 2212 DRH--LFLMDMHHIISDGVSMQIITKEIADLYKGKELAELHIQYKDFAVWQNEWFQSAAL 2269 Query: 189 NRQEEYWLGVFHEPVPALPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTESTL 248 +Q+ YWL F E +P L F+ +Q A L RLA T +TL Sbjct: 2270 EKQKTYWLNTFAEDIPVLNLSTDYPRPTIQSFEGDIVTFSAGKQLAEELKRLATETGTTL 2329 Query: 249 FMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFFACRKLSFQE 308 +M+L+AA+ LL K S E+IVVG P +GR H ++NIVGM VNTLA++ +F E Sbjct: 2330 YMLLLAAYNVLLHKYSGQEEIVVGTPIAGRSHADVENIVGMFVNTLALKNTPIAVRTFHE 2389 Query: 309 YLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAAEQIDAIDMV 368 +L +VK +EA+ENQDYP + L+EKL +L PLF+ MF + ++ +I I+ + Sbjct: 2390 FLLEVKQNALEAFENQDYPFENLIEKLQVRRDLSRNPLFDTMFSLSNIDEQVEI-GIEGL 2448 Query: 369 SFGHDSVP---GKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQVITSN 425 SF + KFD+ F ++++ + Y +LF +E I L + F+ I+Q I N Sbjct: 2449 SFSPYEMQYWIAKFDISFDILEKQDDIQFYFNYCTNLFKKETIERLATHFMHILQEIVIN 2508 Query: 426 LETGLGDL 433 E L ++ Sbjct: 2509 PEIKLCEI 2516 Score = 271 bits (693), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 151/420 (35%), Positives = 246/420 (58%), Gaps = 8/420 (1%) Query: 9 QETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRT 68 ++ YYP S Q+ +F+ ++ GTAYN+P + + G L+ +LE A+KKLV RHE+LRT Sbjct: 1058 EQEYYPVSSVQKRMFILNEFDRSGTAYNLPGVMFLDGKLNYRQLEAAVKKLVERHEALRT 1117 Query: 69 TIELDADSGMLRQKINPAVSFAFPVYELSETETVLLIQDFVRPFRLDKPPLFRTALIRLT 128 + + +G Q+++ V E +E + +I +F++PF L+ PL R L++L Sbjct: 1118 S--FHSINGEPVQRVHQNVELQIAYSESTEDQVERIIAEFMQPFALEVAPLLRVGLVKL- 1174 Query: 129 DREETVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSLLAGTEQW 188 + E + I+DMHHII+DG S+ I+++++A LY+ +EL L +QYKD+ V + L ++ Sbjct: 1175 EAERHLFIMDMHHIISDGVSMQIMIQEIADLYKEKELPTLGIQYKDFTVWHNRLLQSDVI 1234 Query: 189 NRQEEYWLGVFHEPVPAL--PWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTES 246 +QE YWL VF E +P L P D ++ + T F+ +Q L+++A T + Sbjct: 1235 EKQEAYWLNVFTEEIPVLNLPTDYPRPTIQSFDGKRFT--FSTGKQLMDDLYKVATETGT 1292 Query: 247 TLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFFACRKLSF 306 TL+MVL+AA+ LSK S +DIVVG P +GR H ++N++GM VNTLA+R + +F Sbjct: 1293 TLYMVLLAAYNVFLSKYSGQDDIVVGTPIAGRSHADVENMLGMFVNTLAIRSRLNNEDTF 1352 Query: 307 QEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAAE-QIDAI 365 +++L VK + AYEN DYP D LVEKL +L PLF+ MF + +++ I Sbjct: 1353 KDFLANVKQTALHAYENPDYPFDTLVEKLGIQRDLSRNPLFDTMFVLQNTDRKSFEVEQI 1412 Query: 366 DMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQVITSN 425 + + +S KFDL V +E + + + + Y LF+++ + + F++I+ I N Sbjct: 1413 TITPYVPNSRHSKFDLTLEVSEEQNEILLCLEYCTKLFTDKTVERMAGHFLQILHAIVGN 1472 Score = 84.3 bits (207), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 89/343 (25%), Positives = 153/343 (44%), Gaps = 45/343 (13%) Query: 13 YPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTTIEL 72 Y SP Q + L A+ V + I+G++D L E+L L++R++ RTT Sbjct: 13 YRLSPMQEGMLFHALLDKDKNAHLVQMSIAIEGIVDVELLSESLNILIDRYDVFRTT--- 69 Query: 73 DADSGMLRQKINPAVSFAFP----------VYELSETETVLLI-----QDFVRPFRLDKP 117 L +KI + + L E + I QD F L + Sbjct: 70 -----FLHEKIKQPLQVVLKERPVQLQFKDISSLDEEKREQAIEQYKYQDGETVFDLTRD 124 Query: 118 PLFRTALIRLTDREETVLIIDMHHIITDGTSVSILLKDLAALY----ENRELEVLKLQ-Y 172 PL R A+ + T + +I HHI+ DG +I+ DL +Y E + L++ +Q Y Sbjct: 125 PLMRVAIFQ-TGKVNYQMIWSFHHILMDGWCFNIIFNDLFNIYLSLKEKKPLQLEAVQPY 183 Query: 173 KDYAVRQSLLAGTEQWNRQE--EYW---LGVFHEPVPALPWDGRGTEHRAGEDPSRTAYF 227 K + + E+ ++QE YW L + + V LP + + +P++ F Sbjct: 184 KQF------IKWLEKQDKQEALRYWKEHLMNYDQSV-TLP-KKKAAINNTTYEPAQFR-F 234 Query: 228 AIDEQTACALHRLAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHE--GLDN 285 A D+ L R+A ++ TL +V + +L K + D+V G SGR E G++ Sbjct: 235 AFDKVLTQQLLRIANQSQVTLNIVFQTIWGIVLQKYNSTNDVVYGSVVSGRPSEISGIEK 294 Query: 286 IVGMLVNTLAVRFFACRKLSFQEYLYQVKDKLIEAYENQDYPL 328 +VG+ +NTL +R + SF E + V ++ + +++ +PL Sbjct: 295 MVGLFINTLPLRIQTQKDQSFIELVKTVHQNVLFSQQHEYFPL 337 >emb|CAE02631.1| surfactin synthetase B [Bacillus amyloliquefaciens] Length = 3586 Score = 287 bits (735), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 161/426 (37%), Positives = 248/426 (58%), Gaps = 11/426 (2%) Query: 10 ETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTT 69 + +YP S AQR +++ ++L T+YNVP + ++G +D RLEEA++ L+NRHE+LRT+ Sbjct: 1054 QKHYPVSSAQRRMYILNQLGQASTSYNVPAVLLLEGSVDKKRLEEAMQALINRHETLRTS 1113 Query: 70 IELDADSGMLRQKINPAVSFAFPVYELSETETVLLIQDFVRPFRLDKPPLFRTALIRLTD 129 D G + Q I+ VSF E E + L + F+RPF L++ PL R+ LIRL + Sbjct: 1114 --FDMAEGEVVQTIHKNVSFELETAEGREEDAEELTKAFIRPFALNRAPLVRSKLIRL-E 1170 Query: 130 REETVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSLLAGTEQWN 189 + +L+IDMHHIITDG+S+ I + DLA LY+ EL + K+ YKD++V Q A +Q Sbjct: 1171 EDRHLLLIDMHHIITDGSSMGIFIGDLAKLYQGTELALPKIHYKDFSVWQREKANLDQ-- 1228 Query: 190 RQEEYWLGVFHE--PVPALPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTEST 247 E YWL F PV LP D R+ E F +D+Q + +L T++T Sbjct: 1229 -HEAYWLDTFKGDLPVLDLPLDFPRPAERSFE--GERVIFGLDKQVTAQIKKLLADTDTT 1285 Query: 248 LFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFFACRKLSFQ 307 ++M L+AAF LLSK S EDI+VG P +GR H L ++ GM VNT+A+R K +F+ Sbjct: 1286 MYMFLLAAFQVLLSKYSGQEDIIVGSPAAGRQHPDLQDVPGMFVNTVALRSHPAGKKTFK 1345 Query: 308 EYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEME-AAEQIDAID 366 ++L +VK ++A+E+Q YPL+ L+EKL + + PLF+V+F ME A ++ ++ Sbjct: 1346 QFLDEVKTASLQAFEHQSYPLEELIEKLPLTRDTSRSPLFSVLFNMQNMEIPALRLGDLE 1405 Query: 367 MVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQVITSNL 426 + S+ KFDL + +G+ Y ++LF++E I + F+ +I+ N Sbjct: 1406 ISSYSMHHHVAKFDLSLEAAERGEEVGLSFDYAKALFADETIRRWSAHFVNLIKACAENP 1465 Query: 427 ETGLGD 432 + L D Sbjct: 1466 DIQLAD 1471 Score = 225 bits (574), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 136/410 (33%), Positives = 225/410 (54%), Gaps = 5/410 (1%) Query: 13 YPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTTIEL 72 YP S AQ+ +++ ++L +YN+P + ++G ++ RL+EAL +++NRHESLRT+ + Sbjct: 2097 YPLSSAQKRMYVLNQLDRETISYNMPSVLLMEGEVNISRLQEALNQMINRHESLRTSF-I 2155 Query: 73 DADSGMLRQKINPAVSFAFPVYELSETETV-LLIQDFVRPFRLDKPPLFRTALIRLTDRE 131 D + G Q+I ++E ++ E L+IQ F++PF L PL R AL+RL +++ Sbjct: 2156 DQN-GRPMQQIAEQADIDLHIFEAADEEKADLIIQAFIKPFDLSAAPLIRAALVRLNEKK 2214 Query: 132 ETVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSLLAGTEQWNRQ 191 +L++DMHHII DG S S+L+K+LA LY+ L L YKD+AV Q+ E+ Sbjct: 2215 H-LLLLDMHHIIADGVSRSMLVKELAHLYKGGSLPSPNLHYKDFAVWQNEPEQAERMEDH 2273 Query: 192 EEYWLGVFHEPVPALPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTESTLFMV 251 E YWL F +P L ++ F +T A+ L +++ +TL MV Sbjct: 2274 ERYWLSAFSGELPELNLPTDFPRPPVQSFKGQSVRFRAVRETEKAVRELMESSGATLHMV 2333 Query: 252 LMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFFACRKLSFQEYLY 311 L AAF LSK++ DI++G T+GR + + GM VNTLA+R ++ +F L Sbjct: 2334 LHAAFHVFLSKITGQRDIIIGSVTAGRTSAEVQEMPGMFVNTLALRNETRKEQTFAGLLE 2393 Query: 312 QVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAAE-QIDAIDMVSF 370 +VK ++A +QDYP + L+ KL+ ++ PLF VM + + +++ + + + Sbjct: 2394 RVKQTNLDALAHQDYPFEDLIGKLDLPRDMSRNPLFQVMVTTEDPDKETLELENLRITPY 2453 Query: 371 GHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQ 420 + KFDL + LG++ Y LF +E I + +GF+ I++ Sbjct: 2454 ESNQGTAKFDLTLGGFTDQEGLGLQFEYATDLFKKETIEKWSAGFLRILK 2503 Score = 86.3 bits (212), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 106/422 (25%), Positives = 183/422 (43%), Gaps = 43/422 (10%) Query: 13 YPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTTI-- 70 Y +P Q + L ++Y + RI G E+++ +L+ ++ LRT Sbjct: 10 YALTPMQEGMLYHALLDPHSSSYFTQLELRIHGSFQLELFEKSVNELIRTYDILRTVFVH 69 Query: 71 -ELDADSGMLRQKINPAVSFAFPVYELSETETVLLIQDFVRP-----FRLDKPPLFRTAL 124 +L ++ + V + + +L E I+ + R F L K LF+ A+ Sbjct: 70 QQLQKPRQVVLAERKTKVHYE-DISQLDEARQTEYIERYKRGVQQQGFHLAKDILFKAAV 128 Query: 125 IRLTDREETVLIIDMHHIITDGTSVSILLKDLAALYENREL--EVLKLQYKDYAVRQSLL 182 RL+++E L+ HHI+ DG S+ +L+K L YE Q K Y+ L Sbjct: 129 FRLSEKE-LYLVWSNHHIVMDGWSMGVLMKSLFQNYEALRAGRPAGGSQGKPYSDYIKWL 187 Query: 183 AGTEQWNRQEEYW---LGVFHEPVPALPWDGRGTEHRAGEDPSRTAY-FAIDEQTACALH 238 G + + E+YW L F +P LP GR + +D Y F DE+ + Sbjct: 188 GGRD-YEEAEQYWSSRLADFEQP-SLLP--GRLASEK--KDYQNEEYSFVWDEELVAQIQ 241 Query: 239 RLAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHE--GLDNIVGMLVNTLAV 296 + A + T + A + A+LSK + +D+V G SGR E G++ + G+ +NT+ V Sbjct: 242 QTANRHQVTGPNLFQAVWGAVLSKYNYTDDVVFGTVVSGRPSEINGIETMAGLFINTIPV 301 Query: 297 RFFACRKLSFQEYLYQVKDKLIEAYENQDY-PLDRLVEK--LNGSHNLQGRPLFNVMFQF 353 R + +F + + V+ +EA E DY PL + ++ L+GS L N + F Sbjct: 302 RIKIDKDAAFSDVMAAVQKNAVEA-ERYDYVPLYDIQKRSALDGS-------LLNHLVAF 353 Query: 354 AEMEAAEQIDAIDM-------VSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEE 406 ++++ M + H FD + IV + ++I Y + F+ + Sbjct: 354 ENYPLDKELENGGMEERLGFSIKVEHAFEQTSFDFNLIVY-PGKTWTVKIKYNGAAFAHD 412 Query: 407 AI 408 AI Sbjct: 413 AI 414 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.320 0.136 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 607,379,278 Number of extensions: 24274320 Number of successful extensions: 59870 Number of sequences better than 1.0e-05: 566 Number of HSP's gapped: 57457 Number of HSP's successfully gapped: 1055 Length of query: 443 Length of database: 757,237,578 Length adjustment: 129 Effective length of query: 314 Effective length of database: 406,989,807 Effective search space: 127794799398 Effective search space used: 127794799398 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 127 (53.5 bits)