BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0587.0002.p (612 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongen... 212 3e-53 ref|NP_782429.1| two-component sensor kinase yesM [Clostridium t... 204 5e-51 ref|NP_244314.1| two-component sensor histidine kinase [Bacillus... 188 3e-46 ref|NP_345167.1| sensor histidine kinase, putative [Streptococcu... 180 8e-44 ref|NP_358173.1| Histidine kinase [Streptococcus pneumoniae R6] ... 178 3e-43 >ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongensis] gb|AAM25485.1| predicted ATPase [Thermoanaerobacter tengcongensis] Length = 593 Score = 212 bits (539), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 131/442 (29%), Positives = 218/442 (49%), Gaps = 18/442 (4%) Query: 165 GYSHWFGMEKRSY-LTSNPDSPVLTLGKMVINIDTGEPLGTLFLIVREEQLSAFLQSSDP 223 G W +E + L + P + + +++++ +T +P G L + + + + Sbjct: 155 GAPMWLSLENLPFDLIIKNNYPKIAMARVLLDFNTYKPEGLLVICINIPTIEKVYSENLK 214 Query: 224 AASKAYYFVDEHRRVVAAADKSSLLQPLEPSMAARIGDRERADRA-ASFSYKDDGNLVTV 282 A++ D + +++ S P A I + D+ + LVT Sbjct: 215 EKESAFFIADRNGNIISF---KSTFSGFTPKSAQNILAKYLKDKQNVVININSSKLLVTS 271 Query: 283 SRFGRMDWELINVVSLKLLTADVQQNVRLTAL-----VGALCLIFSLFGASFLSRMVASP 337 S DW L++VVSLK + ++R++ + + CL+F+ + + SR + P Sbjct: 272 SPIPTSDWRLVSVVSLK----NAINSIRISFIEFYLRILVFCLLFAFLVSMYFSRALTHP 327 Query: 338 LERLTRAMRQVVSGDLRPVAA--ARTEDEIGTIAEAFNFMVGRVRELLKKVTEEQKRKRE 395 LERL +M++V G+L ++DEI + + +N MV R+ +L+ ++ + + KRE Sbjct: 328 LERLANSMKKVRQGNLEEKVEFEYHSKDEIAIVIKEYNRMVERINDLINRILKLEINKRE 387 Query: 396 YELALISAQIKPHFLYNTLDTIYVLNELDRNEEARDTTKALADFYRMVLNKGRELIILEK 455 EL + AQI PHFLYNTLDTI+ E ++ E + +L+ +R+ LN+G E I + Sbjct: 388 AELKALEAQINPHFLYNTLDTIFWKAEKAKDRELSEMIYSLSRLFRLTLNRGEEFIQVRG 447 Query: 456 EARITDDYLAIMQIRYPDVFRYEIDIPAELSGTPIPKLSLQPLVENAIYHGLKKKGSKGF 515 E + + YL + RY + F+Y + I E+ IPKL LQP VENAI HGL+ + F Sbjct: 448 EKELIERYLFLQSKRYKNKFKYSVKISDEILDYYIPKLILQPFVENAIVHGLENNSEESF 507 Query: 516 IRIQACSTGGKVLVQVTDNGIGMDEERIEAIMSGYSPE--EETRSIGTYSVQQRLNLYFG 573 + + G + + DNG GM EE +E + E EE +V +RL LY+G Sbjct: 508 VEVIGEKEGENLKFIIKDNGPGMSEETLEKLKRFIESENIEEKVGYAIRNVNERLRLYYG 567 Query: 574 EPYGLTVRSVVDEGTVVELSLP 595 + Y L + S EGT + L LP Sbjct: 568 DKYELKIESRQGEGTTISLILP 589 >ref|NP_782429.1| two-component sensor kinase yesM [Clostridium tetani E88] gb|AAO36366.1| two-component sensor kinase yesM [Clostridium tetani E88] Length = 577 Score = 204 bits (519), Expect = 5e-51, Method: Compositional matrix adjust. Identities = 109/311 (35%), Positives = 173/311 (55%), Gaps = 2/311 (0%) Query: 289 DWELINVVSLKLLTADVQQNVRLTALVGALCLIFSLFGASFLSRMVASPLERLTRAMRQV 348 +W L +V K + + Q + L VG + L+ ++ + +S + P+ RL M ++ Sbjct: 261 NWILCIIVENKKIHTQINQIINLILFVGLILLLAAILLSIVISGSIVKPIHRLKSNMLEI 320 Query: 349 VSGDLRPVAAARTEDEIGTIAEAFNFMVGRVRELLKKVTEEQKRKREYELALISAQIKPH 408 G+ + DEI + + FN M+ ++ L+ KV + +K+KR EL ++ +QI PH Sbjct: 321 SKGNFDSYYEIKNNDEISILGQVFNQMLTDIKRLINKVYQVEKQKRSAELRVLQSQINPH 380 Query: 409 FLYNTLDTIYVLNELDRNE-EARDTTKALADFYRMVLNKGRELIILEKEARITDDYLAIM 467 FLYNTLDTI L+ N E D L++F+R+ L+ G+E I + E +YL I Sbjct: 381 FLYNTLDTIQ-WKALEYNAFEVVDMINYLSNFFRISLSDGKEFITISDEVAHVSNYLEIQ 439 Query: 468 QIRYPDVFRYEIDIPAELSGTPIPKLSLQPLVENAIYHGLKKKGSKGFIRIQACSTGGKV 527 +IRY D Y +D+ + L IPKL +QPLVEN+IYHGLK + KG I + S G + Sbjct: 440 KIRYKDKISYSMDVDSSLDQYLIPKLIVQPLVENSIYHGLKLQKHKGIINVSISSKDGFL 499 Query: 528 LVQVTDNGIGMDEERIEAIMSGYSPEEETRSIGTYSVQQRLNLYFGEPYGLTVRSVVDEG 587 ++V DNG+GMD E++ + ET G Y++ +RL L FG+ Y + ++S + G Sbjct: 500 FIKVIDNGLGMDVEQLRTLRKNLWESIETNHYGLYNINERLKLAFGKKYSIEIKSELKIG 559 Query: 588 TVVELSLPMLG 598 T V L +P++ Sbjct: 560 TQVLLRIPLIS 570 >ref|NP_244314.1| two-component sensor histidine kinase [Bacillus halodurans] pir||G84080 two-component sensor histidine kinase BH3447 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07166.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 602 Score = 188 bits (478), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 106/318 (33%), Positives = 169/318 (53%), Gaps = 10/318 (3%) Query: 290 WELINVVSLKLLTADVQQNVRLTALVGALCLIFSLFGASFLSRMVASPLERLTRAMRQVV 349 W LI V S +VQQ + + + FLS ++ P+ +L AM++ Sbjct: 276 WTLIGVFSTDQSVEEVQQILFYVVTFVFFVCFVGITASYFLSYTISRPINQLMLAMQKAE 335 Query: 350 SGDLRPVAAARTEDEIGTIAEAFNFMVGRVRELLKKVTEEQKRKREYELALISAQIKPHF 409 SGDL +DE+G + +FN M+ ++ +L+ ++++KRE EL + A IKPHF Sbjct: 336 SGDLTSRYEGEEQDEVGRLGRSFNTMIEQIGKLISLTERQERKKREAELHSLQANIKPHF 395 Query: 410 LYNTLDTIYVLNELDRNEEARDTTKALADFYRMVLNKGRELIILEKEARITDDYLAIMQI 469 LYNTLDTI + + D AL+ +R+ L+KG +I L E +YL I + Sbjct: 396 LYNTLDTIQWMARKKNASDVADLVGALSKLFRIGLSKGGTIIPLVDEIEHIKNYLQIQSV 455 Query: 470 RYPDVFRYEIDIPAELSGTPIPKLSLQPLVENAIYHGLKKKGSKGFIRIQACSTGGKVLV 529 RY + Y + +P+ + I K+ LQP+VENAIYHG+K++ G I I+A +++ Sbjct: 456 RYKNKLNYSLVMPSNMERLSILKIVLQPIVENAIYHGIKERRGPGLITIEAERENDMLII 515 Query: 530 QVTDNGIGMDEERIEAIMSGYS----------PEEETRSIGTYSVQQRLNLYFGEPYGLT 579 ++ DNG G+ E ++ + + + + T+ G +V RL L FGEPYG+ Sbjct: 516 RIRDNGKGIKPETLQQLRTNVNLFLEKGDKEGGQRLTKGYGLINVHARLRLTFGEPYGVK 575 Query: 580 VRSVVDEGTVVELSLPML 597 + SV +EGTVV + P+L Sbjct: 576 IDSVFNEGTVVTIFHPIL 593 >ref|NP_345167.1| sensor histidine kinase, putative [Streptococcus pneumoniae TIGR4] pir||F95076 sensor histidine kinase, probable [imported] - Streptococcus pneumoniae (strain TIGR4) emb|CAB54581.1| histidine kinase [Streptococcus pneumoniae] gb|AAF31453.1| putative histidine kinase [Streptococcus pneumoniae] gb|AAK74807.1| sensor histidine kinase, putative [Streptococcus pneumoniae TIGR4] Length = 563 Score = 180 bits (457), Expect = 8e-44, Method: Compositional matrix adjust. Identities = 123/407 (30%), Positives = 201/407 (49%), Gaps = 37/407 (9%) Query: 199 GEPLGTLFLIVREEQLSAFLQSSDPAASKAYYFVDEHRRVV-----AAADKSSLLQPLEP 253 G LG L L + E L A+L + ++E+ V SS ++ ++P Sbjct: 173 GANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQHTVYSSSSKMEAMKP 232 Query: 254 SMAARIGDRERADRAASFSYKDDGNLVTVSRFGRMDWELINVVSLKLLTADVQQNVRLTA 313 + D + SY V+ + DW ++ V SL+ L D ++ L Sbjct: 233 YI-----DTGQGYTPGHKSY------VSQEKIAGTDWTVLGVSSLEKL--DQVRSQLLWT 279 Query: 314 LVGA------LCLIFSLFGASFLSRMVASPLERLTRAMRQVVSGDLRPVAAARTEDEIGT 367 L+GA +CL F L R +A PL+ L M ++ SG A E+ Sbjct: 280 LLGASVTSLLVCLCLVWFS---LKRWIA-PLKDLRETMLEIASGAQNLRAKEVGAYELRE 335 Query: 368 IAEAFNFMVGRVRELLKKVTEEQKRKREYELALISAQIKPHFLYNTLDTIYVLNELDRNE 427 + FN M+ ++ +L+ + +++ R+Y+L +S+QI PHFLYNTLDTI + E ++ Sbjct: 336 VTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFHDSQ 395 Query: 428 EARDTTKALADFYRMVLNKGRELIILEKEARITDDYLAIMQIRYPDVFRYEIDIPAELSG 487 TK+LA ++R+ LN+G++LI L E YL I + RY D YEI+ Sbjct: 396 RVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINENVAFDN 455 Query: 488 TPIPKLSLQPLVENAIYHGLKKKGSKGFIRIQACSTGGKVLVQVTDNGIGMDEERIEAIM 547 +PKL LQPLVENA+YHG+K+K +G I++ +++++ D+G+G + Sbjct: 456 LVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD------- 508 Query: 548 SGYSPEEETR--SIGTYSVQQRLNLYFGEPYGLTVRSVVDEGTVVEL 592 +G S + + + +G +V QRL L+FG Y + + S +GT VE+ Sbjct: 509 AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYHMKIDSRPQKGTKVEI 555 >ref|NP_358173.1| Histidine kinase [Streptococcus pneumoniae R6] pir||C97944 histidine kinase (EC 2.7.3.-) [imported] - Streptococcus pneumoniae (strain R6) gb|AAK99383.1| Histidine kinase [Streptococcus pneumoniae R6] Length = 563 Score = 178 bits (452), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 123/407 (30%), Positives = 200/407 (49%), Gaps = 37/407 (9%) Query: 199 GEPLGTLFLIVREEQLSAFLQSSDPAASKAYYFVDEHRRVV-----AAADKSSLLQPLEP 253 G LG L L + E L A+L + ++E+ V SS ++ ++P Sbjct: 173 GANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQHTVYSSSSKMEAMKP 232 Query: 254 SMAARIGDRERADRAASFSYKDDGNLVTVSRFGRMDWELINVVSLKLLTADVQQNVRLTA 313 + G SY V+ + DW ++ V SL+ L D ++ L Sbjct: 233 YIETGQGYT-----PGHKSY------VSQEKIAGTDWTVLGVSSLEKL--DQVRSQLLWT 279 Query: 314 LVGA------LCLIFSLFGASFLSRMVASPLERLTRAMRQVVSGDLRPVAAARTEDEIGT 367 L+GA +CL F L R +A PL+ L M ++ SG A E+ Sbjct: 280 LLGASVTSLLVCLCLVWFS---LKRWIA-PLKDLRETMLEIASGAQNLRAKEVGAYELRE 335 Query: 368 IAEAFNFMVGRVRELLKKVTEEQKRKREYELALISAQIKPHFLYNTLDTIYVLNELDRNE 427 + FN M+ ++ +L+ + +++ R+Y+L +S+QI PHFLYNTLDTI + E ++ Sbjct: 336 VTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFHDSQ 395 Query: 428 EARDTTKALADFYRMVLNKGRELIILEKEARITDDYLAIMQIRYPDVFRYEIDIPAELSG 487 TK+LA ++R+ LN+G++LI L E YL I + RY D YEI+ Sbjct: 396 RVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINENVAFDN 455 Query: 488 TPIPKLSLQPLVENAIYHGLKKKGSKGFIRIQACSTGGKVLVQVTDNGIGMDEERIEAIM 547 +PKL LQPLVENA+YHG+K+K +G I++ +++++ D+G+G + Sbjct: 456 LVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD------- 508 Query: 548 SGYSPEEETR--SIGTYSVQQRLNLYFGEPYGLTVRSVVDEGTVVEL 592 +G S + + + +G +V QRL L+FG Y + + S +GT VE+ Sbjct: 509 AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEI 555 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.135 0.374 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 786,343,277 Number of extensions: 31405012 Number of successful extensions: 91329 Number of sequences better than 1.0e-05: 221 Number of HSP's gapped: 91288 Number of HSP's successfully gapped: 221 Length of query: 612 Length of database: 757,237,578 Length adjustment: 132 Effective length of query: 480 Effective length of database: 398,844,510 Effective search space: 191445364800 Effective search space used: 191445364800 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 129 (54.3 bits)