BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0586.0070.p (698 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_243333.1| DNA topoisomerase I [Bacillus halodurans] >gi|1... 1009 0.0 ref|NP_389494.1| DNA topoisomerase I [Bacillus subtilis] >gi|730... 930 0.0 ref|NP_464800.1| highly similar to DNA topoisomerase I TopA [Lis... 919 0.0 ref|NP_657801.1| Topoisom_bac, DNA topoisomerase [Bacillus anthr... 917 0.0 ref|NP_470650.1| highly similar to DNA topoisomerase I TopA [Lis... 917 0.0 >ref|NP_243333.1| DNA topoisomerase I [Bacillus halodurans] sp|Q9KA23|TOP1_BACHD DNA topoisomerase I (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) pir||C83958 DNA topoisomerase I topA [imported] - Bacillus halodurans (strain C-125) dbj|BAB06186.1| DNA topoisomerase I [Bacillus halodurans] Length = 690 Score = 1009 bits (2609), Expect = 0.0, Method: Compositional matrix adjust. Identities = 467/688 (67%), Positives = 574/688 (83%), Gaps = 1/688 (0%) Query: 1 MADALVIVESPAKAKTIGKYLGSKYIVKASMGHIRDLPKSQIGVEVENDFSPKYITIRGK 60 MAD LVIVESPAKAKTIGKYLG KY VKASMGH+RDLPKSQ+GV++E+++SP+YITIRGK Sbjct: 1 MADYLVIVESPAKAKTIGKYLGKKYTVKASMGHVRDLPKSQMGVDIEDEYSPRYITIRGK 60 Query: 61 GSILKELKDASKKVKKVYLAADPDREGEAIAWHLAHALDLDNSEECRVVFNEITKQAVKD 120 G +LKELK A+KKVK+VYLAADPDREGEAIAWHLAH+LD+D + ECRVVFNEITKQA+KD Sbjct: 61 GPVLKELKSAAKKVKRVYLAADPDREGEAIAWHLAHSLDIDETSECRVVFNEITKQAIKD 120 Query: 121 AFKTPRKINMDLVNAQQARRILDRLVGYKISPLLWKKVKKGLSAGRVQSVAVKIIMDREN 180 AFK+PR INMDLV+AQQARR+LDRLVGY ISPLLWKKVKKGLSAGRVQSVAVK+I+DRE Sbjct: 121 AFKSPRPINMDLVDAQQARRVLDRLVGYNISPLLWKKVKKGLSAGRVQSVAVKMIIDREK 180 Query: 181 EISAFVPTEYWSITAKLGIRDALFEAKFHKLNGEKKELGNENDVKEVLDAIKDAAFKVSE 240 EI AF P EYWSI + FEAKF+ NG+K EL +E+DV VL +K F V Sbjct: 181 EIQAFEPEEYWSIQGTFALDGEPFEAKFYGTNGKKVELKSEDDVNNVLAKLKGDQFHVDS 240 Query: 241 VKEKERQRHPSAPFTTSSLQQEAARKLGFRAAKTMSVAQQLYEGVELGKEGTVGLITYMR 300 V++KER+R+P +PFTTSSLQQEAARKL FRA KTM +AQQLYEG++LGKEGTVGLITYMR Sbjct: 241 VQKKERKRNPVSPFTTSSLQQEAARKLNFRAKKTMMLAQQLYEGIDLGKEGTVGLITYMR 300 Query: 301 TDSTRLSATAQEEAKELILAKYGEKFVPESPRQYSKKAAGAQDAHEAIRPTSALREPEMV 360 TDSTR+S TA+ E KE I +K+G+++ ++ + KK +QDAHEAIRPTS R+P+ + Sbjct: 301 TDSTRISDTAKAETKEYIESKFGKEYA-QNGTKAVKKDKKSQDAHEAIRPTSVERDPKSL 359 Query: 361 KEFMSRDQFRLYKLIWERFVSSQMSSAVLDTLSVDITAGTAVFRAVGSKVSFPGFMKVYV 420 KE++SRDQ RLYKLIWER V+SQM+ A++DT++VD++ +FRA GSKV FPGFMKVY+ Sbjct: 360 KEYLSRDQLRLYKLIWERLVASQMAPAIMDTMTVDLSNEGVLFRATGSKVKFPGFMKVYI 419 Query: 421 EGNDDGTTDEEKFLPPLQAGDDLKKQEIEPKQHFTQPPPRYTEARLVKTLEELGIGRPST 480 EGND+G +E++ LP LQ G + K+EIEP QHFTQPPPRYTEARLVKT+EELGIGRPST Sbjct: 420 EGNDEGKKEEDRLLPNLQEGQTVTKEEIEPSQHFTQPPPRYTEARLVKTMEELGIGRPST 479 Query: 481 YAPTLETIQKRGYVAIEEKKFMPTELGELIIEQMEQFFPEILDVEFTAHMEDDLDHVEDG 540 YAPTL+TIQKRGYVA++E++F+PTELGE+++E M +FFPEILDVEFTA MEDDLD +E+G Sbjct: 480 YAPTLDTIQKRGYVALDERRFVPTELGEIVLELMTEFFPEILDVEFTAKMEDDLDSIEEG 539 Query: 541 EEDWVKVLAEFYTSFEKRLVFAXXXXXXXXXXXXVSDEMCEKCGKPMVYKLGRFGKFLAC 600 ++ W+K++ +FY FE+RL A + EMCEKCG MVYK+GR+GKF+AC Sbjct: 540 KQQWIKIIDDFYKGFEERLKVAEEEMKEVEIKDEPTGEMCEKCGHEMVYKMGRYGKFMAC 599 Query: 601 SGFPDCRNTKPIVKDIGVSCPKCHEGKVVERRSKKGRVFYGCDQYPGCDFVSWDRPSVKP 660 S FPDCRNTKPIVK+IGV CPKC +G++VER+SKK RVFYGC+QYP CDFVSWD+P + Sbjct: 600 SNFPDCRNTKPIVKEIGVKCPKCEKGEIVERKSKKRRVFYGCNQYPECDFVSWDKPIARS 659 Query: 661 CPVCGSWMIEKRSKQGTKLQCTSCDHTE 688 CP C S+++EKR+K+ ++QC+SCD+ E Sbjct: 660 CPKCSSYLVEKRTKKQVQVQCSSCDYKE 687 >ref|NP_389494.1| DNA topoisomerase I [Bacillus subtilis] sp|P39814|TOP1_BACSU DNA topoisomerase I (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) pir||G69724 DNA topoisomerase I topA - Bacillus subtilis gb|AAA22763.1| DNA topoisomerase I emb|CAA04422.1| DNA Topoisomerase I [Bacillus subtilis] emb|CAB13485.1| DNA topoisomerase I [Bacillus subtilis subsp. subtilis str. 168] Length = 691 Score = 930 bits (2403), Expect = 0.0, Method: Compositional matrix adjust. Identities = 452/688 (65%), Positives = 548/688 (79%), Gaps = 1/688 (0%) Query: 1 MADALVIVESPAKAKTIGKYLGSKYIVKASMGHIRDLPKSQIGVEVENDFSPKYITIRGK 60 M+D LVIVESPAKAKTI +YLG KY VKASMGH+RDLPKSQ+GV++E +F PKYITIRGK Sbjct: 1 MSDYLVIVESPAKAKTIERYLGKKYKVKASMGHVRDLPKSQMGVDIEQNFEPKYITIRGK 60 Query: 61 GSILKELKDASKKVKKVYLAADPDREGEAIAWHLAHALDLDNSEECRVVFNEITKQAVKD 120 G +LKELK A+KK KKVYLAADPDREGEAIAWHLAH+LDLD + +CRVVFNEITK A+K+ Sbjct: 61 GPVLKELKTAAKKAKKVYLAADPDREGEAIAWHLAHSLDLDLNSDCRVVFNEITKDAIKE 120 Query: 121 AFKTPRKINMDLVNAQQARRILDRLVGYKISPLLWKKVKKGLSAGRVQSVAVKIIMDREN 180 +FK PR INMDLV+AQQARRILDRLVGYKISP+LWKKVKKGLSAGRVQSVA+++I+DRE Sbjct: 121 SFKHPRMINMDLVDAQQARRILDRLVGYKISPILWKKVKKGLSAGRVQSVALRLIIDREK 180 Query: 181 EISAFVPTEYWSITAKLGIRDALFEAKFHKLNGEKKELGNENDVKEVLDAIKDAAFKVSE 240 EI+ F P EYW+I FEA F NG+K L +E DVKE+L +K + V + Sbjct: 181 EINDFKPEEYWTIDGTFLKGQETFEASFFGKNGKKLPLNSEADVKEILSQLKGNQYTVEK 240 Query: 241 VKEKERQRHPSAPFTTSSLQQEAARKLGFRAAKTMSVAQQLYEGVELGKEGTVGLITYMR 300 V +KER+R+P+ PFTTS+LQQEAARKL FRA KTM +AQQLYEG++LG+EGTVGLITYMR Sbjct: 241 VTKKERKRNPALPFTTSTLQQEAARKLNFRAKKTMMIAQQLYEGIDLGREGTVGLITYMR 300 Query: 301 TDSTRLSATAQEEAKELILAKYGEKFVPESPRQYSKKAAGAQDAHEAIRPTSALREPEMV 360 TDSTR+S TA +EA I YG++F+ R+ +KK AQDAHEAIRPTS LR+P + Sbjct: 301 TDSTRISNTAVDEAAAFIDQTYGKEFLG-GKRKPAKKNENAQDAHEAIRPTSVLRKPSEL 359 Query: 361 KEFMSRDQFRLYKLIWERFVSSQMSSAVLDTLSVDITAGTAVFRAVGSKVSFPGFMKVYV 420 K + RDQ RLYKLIWERFV+SQM+ AVLDT+SVD+T FRA GSKV F GFMKVYV Sbjct: 360 KAVLGRDQMRLYKLIWERFVASQMAPAVLDTMSVDLTNNGLTFRANGSKVKFSGFMKVYV 419 Query: 421 EGNDDGTTDEEKFLPPLQAGDDLKKQEIEPKQHFTQPPPRYTEARLVKTLEELGIGRPST 480 EG DD ++++ LP LQ GD + ++IEP+QHFTQPPPRYTEARLVKTLEE GIGRPST Sbjct: 420 EGKDDQMEEKDRMLPDLQEGDTVLSKDIEPEQHFTQPPPRYTEARLVKTLEERGIGRPST 479 Query: 481 YAPTLETIQKRGYVAIEEKKFMPTELGELIIEQMEQFFPEILDVEFTAHMEDDLDHVEDG 540 YAPTL+TIQ+RGYVA++ K+F+PTELG+++++ + +FFPEI++VEFTA ME DLDHVE+G Sbjct: 480 YAPTLDTIQRRGYVALDNKRFVPTELGQIVLDLIMEFFPEIINVEFTAKMERDLDHVEEG 539 Query: 541 EEDWVKVLAEFYTSFEKRLVFAXXXXXXXXXXXXVSDEMCEKCGKPMVYKLGRFGKFLAC 600 +WVK++ FYT FEKR+ A + E CE C PMVYK+GR+GKFLAC Sbjct: 540 NTEWVKIIDNFYTDFEKRVKKAESEMKEVEIEPEYAGEDCELCSSPMVYKMGRYGKFLAC 599 Query: 601 SGFPDCRNTKPIVKDIGVSCPKCHEGKVVERRSKKGRVFYGCDQYPGCDFVSWDRPSVKP 660 S FPDCRNTKPIVK IGV CP C EG +VER+SKK RVFYGCD+YP C+FVSWD+P + Sbjct: 600 SNFPDCRNTKPIVKQIGVKCPSCGEGNIVERKSKKKRVFYGCDRYPDCEFVSWDKPIERK 659 Query: 661 CPVCGSWMIEKRSKQGTKLQCTSCDHTE 688 CP CG ++EK+ K+G ++QC CD+ E Sbjct: 660 CPKCGKMLVEKKLKKGIQVQCVECDYKE 687 >ref|NP_464800.1| highly similar to DNA topoisomerase I TopA [Listeria monocytogenes EGD-e] pir||AC1234 DNA topoisomerase I TopA homolog topA [imported] - Listeria monocytogenes (strain EGD-e) emb|CAC99353.1| topA [Listeria monocytogenes] Length = 692 Score = 919 bits (2375), Expect = 0.0, Method: Compositional matrix adjust. Identities = 444/691 (64%), Positives = 553/691 (80%), Gaps = 2/691 (0%) Query: 1 MADALVIVESPAKAKTIGKYLGSKYIVKASMGHIRDLPKSQIGVEVENDFSPKYITIRGK 60 MAD LVIVESPAKAKTI KYLG K+ VKASMGH+RDLPKSQ+GV+ END+ P+YITIRGK Sbjct: 1 MADYLVIVESPAKAKTIEKYLGKKFKVKASMGHVRDLPKSQMGVDTENDYEPRYITIRGK 60 Query: 61 GSILKELKDASKKVKKVYLAADPDREGEAIAWHLAHALDLDNSEECRVVFNEITKQAVKD 120 G +LKELK A+KK KKVYLAADPDREGEAIAWHLA++L+LD S++ RVVFNEITK+AVK+ Sbjct: 61 GPVLKELKQAAKKAKKVYLAADPDREGEAIAWHLANSLELDQSDKLRVVFNEITKEAVKE 120 Query: 121 AFKTPRKINMDLVNAQQARRILDRLVGYKISPLLWKKVKKGLSAGRVQSVAVKIIMDREN 180 +FKTPRKI+MDLVNAQQARRILDRLVGY ISP+LWKKVKKGLSAGRVQS+A++II+DRE Sbjct: 121 SFKTPRKIDMDLVNAQQARRILDRLVGYNISPILWKKVKKGLSAGRVQSIALRIIIDREK 180 Query: 181 EISAFVPTEYWSITAKLGIRDALFEAKFHKLNGEKKELGNENDVKEVLDAIKDAAFKVSE 240 EI+ F P EYW+I F+A F+ +NG+KK+L +DVKEV+ AIK +F V++ Sbjct: 181 EINNFKPEEYWTIDGNFLKGKKKFQANFYGVNGKKKKLSTADDVKEVMSAIKGKSFDVTD 240 Query: 241 VKEKERQRHPSAPFTTSSLQQEAARKLGFRAAKTMSVAQQLYEGVELGKEGTVGLITYMR 300 V +KER R+P+APFTTSSLQQEAARKL +R KTM +AQQLYEG+ LGK+GTVGLITYMR Sbjct: 241 VTKKERLRNPAAPFTTSSLQQEAARKLNYRTRKTMMLAQQLYEGITLGKQGTVGLITYMR 300 Query: 301 TDSTRLSATAQEEAKELILAKYGEKFVPESPRQYSKKAAGAQDAHEAIRPTSALREPEMV 360 TDSTR++ +A EA I YG +F R K A GAQDAHEAIRPTSA+R P+ V Sbjct: 301 TDSTRIADSAILEASNYIKETYGPEFSRNHKRS-DKNAKGAQDAHEAIRPTSAMRSPQEV 359 Query: 361 KEFMSRDQFRLYKLIWERFVSSQMSSAVLDTLSVDITAGTAVFRAVGSKVSFPGFMKVYV 420 KE+++RDQ RLY+LIWERF++SQM+ AVLDT+ VD+ FRA GSK+ F GFMKVYV Sbjct: 360 KEYLTRDQLRLYRLIWERFIASQMTPAVLDTMRVDLDNNGVNFRANGSKIKFHGFMKVYV 419 Query: 421 EGNDDGTTDEEKFLPPLQAGDDLKKQEIEPKQHFTQPPPRYTEARLVKTLEELGIGRPST 480 E NDD T ++E LP L+ GD ++ + +E +QHFTQPPPRYTEARLVKTLEE+GIGRPST Sbjct: 420 ESNDDNTEEKENILPDLKKGDKVQSESLEQRQHFTQPPPRYTEARLVKTLEEIGIGRPST 479 Query: 481 YAPTLETIQKRGYVAIEEKKFMPTELGELIIEQMEQFFPEILDVEFTAHMEDDLDHVEDG 540 Y+PTL+TIQ+R YV++ K+F+PTELGE++ E +E++FPEILDV+FTA+ME +LD VE G Sbjct: 480 YSPTLDTIQRRNYVSLTNKRFIPTELGEIVNEMIEEYFPEILDVKFTANMESELDEVEHG 539 Query: 541 EEDWVKVLAEFYTSFEKRLVFAXXXXXXXXXXXXVSDEMCEKCGKPMVYKLGRFGKFLAC 600 E +WVKV+ EFY FE ++ A + C+ CG PMVYK+G++GKFLAC Sbjct: 540 EVEWVKVIDEFYKRFEPNVIKADAEMEKIEIKDEPAGIDCDLCGAPMVYKMGKYGKFLAC 599 Query: 601 SGFPDCRNTKPIVKDIGVSCPKCHEGKVVERRSKKGRVFYGCDQYPGCDFVSWDRPSVKP 660 S FPDCRNTK IVK+IGV+CPKC +G V+ER+SKK R+FYGCD+YP CD+VSWD+P + Sbjct: 600 SRFPDCRNTKAIVKEIGVTCPKCEKGHVIERKSKKKRIFYGCDRYPDCDYVSWDKPVERA 659 Query: 661 CPVC-GSWMIEKRSKQGTKLQCTSCDHTEAV 690 CP C ++EK+ K+G ++QCT+CD+ E+ Sbjct: 660 CPKCEKRALVEKKLKKGVQVQCTNCDYKEST 690 >ref|NP_657801.1| Topoisom_bac, DNA topoisomerase [Bacillus anthracis A2012] ref|NP_846214.1| DNA topoisomerase I [Bacillus anthracis str. Ames] gb|AAP27700.1| DNA topoisomerase I [Bacillus anthracis str. Ames] Length = 692 Score = 917 bits (2371), Expect = 0.0, Method: Compositional matrix adjust. Identities = 439/689 (63%), Positives = 550/689 (79%), Gaps = 2/689 (0%) Query: 1 MADALVIVESPAKAKTIGKYLGSKYIVKASMGHIRDLPKSQIGVEVENDFSPKYITIRGK 60 M+D LVIVESP+KAKTI KYLG KY V ASMGH+RDLPKSQ+G+EV+N+F+PKYITIRGK Sbjct: 1 MSDYLVIVESPSKAKTIEKYLGKKYKVVASMGHVRDLPKSQMGIEVKNNFTPKYITIRGK 60 Query: 61 GSILKELKDASKKVKKVYLAADPDREGEAIAWHLAHALDLDNSEECRVVFNEITKQAVKD 120 G +LK+LK A+KK KKVYLAADPDREGEAIAWHLA+ L++D +CRVVFNEITK A+K+ Sbjct: 61 GPVLKDLKSAAKKAKKVYLAADPDREGEAIAWHLANTLNVDVESDCRVVFNEITKDAIKE 120 Query: 121 AFKTPRKINMDLVNAQQARRILDRLVGYKISPLLWKKVKKGLSAGRVQSVAVKIIMDREN 180 +FK PR INMDLV+AQQARRILDRLVGY ISPLLWKKVKKGLSAGRVQSVAV++I++RE Sbjct: 121 SFKHPRAINMDLVDAQQARRILDRLVGYNISPLLWKKVKKGLSAGRVQSVAVRLIIERER 180 Query: 181 EISAFVPTEYWSITAKLGIRDALFEAKFHKLNGEKKELGNENDVKEVLDAIKDAAFKVSE 240 EI +F P E+W+I + FEA F+ ++GEK +L NE V E+++ +KD AF V Sbjct: 181 EIQSFEPEEFWTIKTEFVKGKDTFEASFYGVDGEKVQLTNETQVNEIIEQLKDNAFSVEN 240 Query: 241 VKEKERQRHPSAPFTTSSLQQEAARKLGFRAAKTMSVAQQLYEGVELGKEGTVGLITYMR 300 V KER+R+P+ PFTTSSLQQEAARKL RA KTM +AQQLYEG++LGK+GTVGLITYMR Sbjct: 241 VTRKERKRNPALPFTTSSLQQEAARKLNMRAKKTMMLAQQLYEGIDLGKQGTVGLITYMR 300 Query: 301 TDSTRLSATAQEEAKELILAKYGEKFVPESPRQYSKKAAGAQDAHEAIRPTSALREPEMV 360 TDSTR+S TAQ EA+ I YG +++ ++ +KK + AQDAHEAIRPTS +R+PE + Sbjct: 301 TDSTRISETAQTEARTYITEAYGTEYIGAEKKKETKK-SNAQDAHEAIRPTSVMRKPEEL 359 Query: 361 KEFMSRDQFRLYKLIWERFVSSQMSSAVLDTLSVDITAGTAVFRAVGSKVSFPGFMKVYV 420 K F+SRDQ RLYKLIWERFV+SQM+SA++DT++ + FRA GS V FPGFMKVYV Sbjct: 360 KSFLSRDQLRLYKLIWERFVASQMASAIMDTVTARLINNNVQFRASGSVVKFPGFMKVYV 419 Query: 421 EGNDDGTTDEEKFLPPLQAGDDLKKQEIEPKQHFTQPPPRYTEARLVKTLEELGIGRPST 480 E DDG +++K LPPL+ G+ + +++EPKQHFTQPPPRYTEARLV+TLEELGIGRPST Sbjct: 420 ESKDDGAEEKDKMLPPLEVGETVFSKDLEPKQHFTQPPPRYTEARLVRTLEELGIGRPST 479 Query: 481 YAPTLETIQKRGYVAIEEKKFMPTELGELIIEQMEQFFPEILDVEFTAHMEDDLDHVEDG 540 Y PTLETIQKRGYV ++ K+F+PTELGE++IE + +FFPEI+++EFTA+ME LD VE+G Sbjct: 480 YVPTLETIQKRGYVGLDNKRFVPTELGEIVIELILEFFPEIINIEFTANMEQSLDEVEEG 539 Query: 541 EEDWVKVLAEFYTSFEKRLVFAXXXXXXXXXXXXVSDEMCEKCGKPMVYKLGRFGKFLAC 600 +WVK++ +FY FE RL A + E CE C PMV+K+G++GKF+AC Sbjct: 540 NANWVKIVDDFYVGFEPRLEKAEKEMREVEIKDEPAGEDCELCNHPMVFKMGKYGKFMAC 599 Query: 601 SGFPDCRNTKPIVKDIGVSCPKCHEGKVVERRS-KKGRVFYGCDQYPGCDFVSWDRPSVK 659 S FPDCRNTKPIVK+IGV+CPKC +G+++ERRS KK R+FYGC YP CDFVSWD+P + Sbjct: 600 SNFPDCRNTKPIVKEIGVTCPKCDKGQIIERRSNKKKRLFYGCGTYPECDFVSWDKPIGR 659 Query: 660 PCPVCGSWMIEKRSKQGTKLQCTSCDHTE 688 CP C ++EK+ K+G ++QC SCD+ E Sbjct: 660 KCPKCEGMLVEKKLKKGVQVQCISCDYEE 688 >ref|NP_470650.1| highly similar to DNA topoisomerase I TopA [Listeria innocua] pir||AI1596 DNA topoisomerase I TopA homolog topA [imported] - Listeria innocua (strain Clip11262) emb|CAC96545.1| topA [Listeria innocua] Length = 692 Score = 917 bits (2370), Expect = 0.0, Method: Compositional matrix adjust. Identities = 442/691 (63%), Positives = 552/691 (79%), Gaps = 2/691 (0%) Query: 1 MADALVIVESPAKAKTIGKYLGSKYIVKASMGHIRDLPKSQIGVEVENDFSPKYITIRGK 60 MAD LVIVESPAKAKTI KYLG K+ VKASMGH+RDLPKSQ+GV+ E+D+ P+YITIRGK Sbjct: 1 MADYLVIVESPAKAKTIEKYLGKKFKVKASMGHVRDLPKSQMGVDTEHDYEPRYITIRGK 60 Query: 61 GSILKELKDASKKVKKVYLAADPDREGEAIAWHLAHALDLDNSEECRVVFNEITKQAVKD 120 G +LK+LK A+KK KKVYLAADPDREGEAIAWHLA++LDLD S++ RVVFNEITK+AVK+ Sbjct: 61 GPVLKDLKQAAKKAKKVYLAADPDREGEAIAWHLANSLDLDQSDKLRVVFNEITKEAVKE 120 Query: 121 AFKTPRKINMDLVNAQQARRILDRLVGYKISPLLWKKVKKGLSAGRVQSVAVKIIMDREN 180 +FKTPRKI+MDLVNAQQARRILDRLVGY ISP+LWKKVKKGLSAGRVQS+A++II+DRE Sbjct: 121 SFKTPRKIDMDLVNAQQARRILDRLVGYNISPILWKKVKKGLSAGRVQSIALRIIIDREK 180 Query: 181 EISAFVPTEYWSITAKLGIRDALFEAKFHKLNGEKKELGNENDVKEVLDAIKDAAFKVSE 240 EI+ F P EYW+I F+A F+ +NG+K++L +DVKEV+ AIK F V++ Sbjct: 181 EINNFKPEEYWTIDGNFLKGKKKFQANFYGVNGKKRKLSTADDVKEVMSAIKGKTFDVTD 240 Query: 241 VKEKERQRHPSAPFTTSSLQQEAARKLGFRAAKTMSVAQQLYEGVELGKEGTVGLITYMR 300 V +KER R+P+APFTTSSLQQEAARKL +R KTM +AQQLYEG+ LGK+GTVGLITYMR Sbjct: 241 VTKKERLRNPAAPFTTSSLQQEAARKLNYRTRKTMMLAQQLYEGITLGKQGTVGLITYMR 300 Query: 301 TDSTRLSATAQEEAKELILAKYGEKFVPESPRQYSKKAAGAQDAHEAIRPTSALREPEMV 360 TDSTR++ +A EA I YG +F R K A GAQDAHEAIRPTSA+R P+ V Sbjct: 301 TDSTRIADSAILEASNYIKETYGAEFSRNHKRS-DKNAKGAQDAHEAIRPTSAMRSPQEV 359 Query: 361 KEFMSRDQFRLYKLIWERFVSSQMSSAVLDTLSVDITAGTAVFRAVGSKVSFPGFMKVYV 420 KE+++RDQ RLY+LIWERF++SQM+ AVLDT+ VD+ FRA GSK+ F GFMKVYV Sbjct: 360 KEYLTRDQLRLYRLIWERFIASQMTPAVLDTMRVDLDNNGVNFRANGSKIKFHGFMKVYV 419 Query: 421 EGNDDGTTDEEKFLPPLQAGDDLKKQEIEPKQHFTQPPPRYTEARLVKTLEELGIGRPST 480 E NDD T ++E LP L+ GD ++ + +E +QHFTQPPPRYTEARLVKTLEE+GIGRPST Sbjct: 420 ESNDDNTEEKENILPDLKKGDKVQSESLEQRQHFTQPPPRYTEARLVKTLEEIGIGRPST 479 Query: 481 YAPTLETIQKRGYVAIEEKKFMPTELGELIIEQMEQFFPEILDVEFTAHMEDDLDHVEDG 540 Y+PTL+TIQ+R YV++ K+F+PTELGE++ E +E++FPEILDV+FTA+ME +LD VE G Sbjct: 480 YSPTLDTIQRRNYVSLTNKRFVPTELGEIVNEMIEEYFPEILDVKFTANMESELDEVEHG 539 Query: 541 EEDWVKVLAEFYTSFEKRLVFAXXXXXXXXXXXXVSDEMCEKCGKPMVYKLGRFGKFLAC 600 E +WVKV+ EFY FE ++ A + C+ CG PMVYK+G++GKFLAC Sbjct: 540 EVEWVKVIDEFYKQFEPNVIKADAEMEKIEIKDEPAGIDCDLCGAPMVYKMGKYGKFLAC 599 Query: 601 SGFPDCRNTKPIVKDIGVSCPKCHEGKVVERRSKKGRVFYGCDQYPGCDFVSWDRPSVKP 660 S FPDCRNTK IVK+IGV+CPKC +G V+ER+SKK R+FYGCD+YP CD+VSWD+P + Sbjct: 600 SRFPDCRNTKAIVKEIGVTCPKCEKGHVIERKSKKKRIFYGCDRYPDCDYVSWDKPVERA 659 Query: 661 CPVCGS-WMIEKRSKQGTKLQCTSCDHTEAV 690 CP C ++EK+ K+G ++QCT+CD+ E+ Sbjct: 660 CPKCNKRALVEKKLKKGVQVQCTNCDYKEST 690 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.316 0.133 0.386 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 1,006,277,364 Number of extensions: 42827889 Number of successful extensions: 126207 Number of sequences better than 1.0e-05: 1331 Number of HSP's gapped: 121804 Number of HSP's successfully gapped: 1453 Length of query: 698 Length of database: 757,237,578 Length adjustment: 133 Effective length of query: 565 Effective length of database: 396,129,411 Effective search space: 223813117215 Effective search space used: 223813117215 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 130 (54.7 bits)