BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0578.0001.p (395 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00059712.1| COG1051: ADP-ribose pyrophosphatase [Clostrid... 376 e-103 ref|NP_348402.1| Nudix (MutT-like) hydrolase [Clostridium acetob... 213 5e-54 dbj|BAC76070.1| Nudix hydrolase [Synechococcus sp. PCC 7002] 153 7e-36 ref|ZP_00019201.1| hypothetical protein [Chloroflexus aurantiacus] 153 7e-36 ref|ZP_00047746.1| COG1051: ADP-ribose pyrophosphatase [Magnetos... 131 2e-29 >ref|ZP_00059712.1| COG1051: ADP-ribose pyrophosphatase [Clostridium thermocellum ATCC 27405] Length = 317 Score = 376 bits (966), Expect = e-103, Method: Compositional matrix adjust. Identities = 174/297 (58%), Positives = 226/297 (76%) Query: 95 MPKKPVTDRNGLTEEQFLQAYDAGMYERPSVTVDMLIFTVMEQEQDNYRKLSEKSLQLLM 154 M + ++ GLTEE+FL++YDA YERPSVTVDMLIFTV ++++NYRKL EK L+LLM Sbjct: 15 MSESKKVNKQGLTEEEFLESYDASKYERPSVTVDMLIFTVTNEKKENYRKLPEKVLRLLM 74 Query: 155 IQRGEHPYLGQWALPGGFVGVDESLEDAALRELYSETNIDNVYMEQLYTWGDVGRDPRMR 214 I+R +HPY+GQWALPGGF+ +DESLE+ ALREL ETNIDN+YMEQLYTWGDV RDPR R Sbjct: 75 IKRADHPYIGQWALPGGFIKMDESLEEGALRELKEETNIDNIYMEQLYTWGDVNRDPRTR 134 Query: 215 VISSSYIALVDRKTLDVQXXXXXXXXXWFEVTYDVLESGRRELAEGYMEEQKIRITLQKE 274 +IS SY+ALVD L+++ WF V+ ++ + + +GY+ ++ + L E Sbjct: 135 IISVSYMALVDSSNLNIKASDDADDAKWFTVSCNLYQEQKTLTEKGYILQRLYNLRLSDE 194 Query: 275 DVELTGVVTITETVQGHVRRVRREIAENHGFAFDHLKMIQYAIERLRGKVEYTDIIFNLM 334 + L+ V+ + +TV+G V RV REI E+HG AFDH K+I+YA+ERLR K+EYTDI FNLM Sbjct: 195 EDNLSAVIKVVKTVEGRVSRVEREIVESHGIAFDHAKIIEYAVERLRNKIEYTDIAFNLM 254 Query: 335 PPLFTLSELQRVYEIILGRELLAPAFRRKIADSVTETEEFTKDAGHRPSKLYRYRAD 391 P FTL+ELQ+VYE+ILGRELL FRRKIA+ V ET E+TKDAGHRPSKL+R+ + Sbjct: 255 PERFTLTELQQVYEVILGRELLKANFRRKIANMVIETNEYTKDAGHRPSKLFRFNPN 311 >ref|NP_348402.1| Nudix (MutT-like) hydrolase [Clostridium acetobutylicum] pir||C97119 nudix (MutT-like) hydrolase [imported] - Clostridium acetobutylicum gb|AAK79742.1| Nudix (MutT-like) hydrolase [Clostridium acetobutylicum] Length = 307 Score = 213 bits (543), Expect = 5e-54, Method: Compositional matrix adjust. Identities = 132/310 (42%), Positives = 177/310 (57%), Gaps = 38/310 (12%) Query: 102 DRNGLTEEQFLQAYDAGMYERPSVTVDMLIFTVMEQEQDNYRKLSEKSLQLLMIQRGEHP 161 +RNGLTE++FL Y G YERPS TVDML+FTV + + K K+L++L+I+RG+HP Sbjct: 8 NRNGLTEKEFLDRYVPGDYERPSNTVDMLLFTVDDVPIEG--KDPNKALKILLIKRGDHP 65 Query: 162 YLGQWALPGGFVGVDESLEDAALRELYSETNIDNVYMEQLYTWG-DVGRDPRMRVISSSY 220 Y+G WA+PGGFV ++E L A REL ETN++NVY EQL T+G DV RDPRMRVIS +Y Sbjct: 66 YMGCWAVPGGFVNINEGLSSACYRELKEETNVENVYFEQLKTFGDDVNRDPRMRVISVAY 125 Query: 221 IALVDRKTLDVQXXXXXXXXXWFEV----------------TYDV-LESGRRELAEGYME 263 +AL D+ ++ + WF V TY++ L S E GY+ Sbjct: 126 MALADKLSITPKAGDDADDAKWFTVKKRFISSKGFGIDKIDTYNILLTSDDGETKIGYLV 185 Query: 264 EQKIRITLQKEDVELTGVVTITETVQGHVRRVRREIAENHGFAFDHLKMIQYAIERLRGK 323 +K E GVVTI + + E+ AFDH++ I A+ERL+ K Sbjct: 186 TEKF---------EKNGVVTIKVPSYRLLEWSKEEL------AFDHIEEIDCALERLKNK 230 Query: 324 VEYTDIIFNLMPPLFTLSELQRVYEIILGRE--LLAPAFRRKIADSVTETEEFTKDAGHR 381 +EYT I F+ +P FTL E Q+V+E IL E L FRRKI V ETE+ +G R Sbjct: 231 IEYTPIAFSRLPKYFTLREAQKVFEAILNLEKPLTRANFRRKIKKMVVETEKEKITSG-R 289 Query: 382 PSKLYRYRAD 391 P+ Y + D Sbjct: 290 PATCYTFNED 299 >dbj|BAC76070.1| Nudix hydrolase [Synechococcus sp. PCC 7002] Length = 230 Score = 153 bits (386), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 95/278 (34%), Positives = 139/278 (50%), Gaps = 66/278 (23%) Query: 120 YERPSVTVDMLIFTVMEQEQDNYRKLSEKSLQLLMIQRGEHPYLGQWALPGGFVGVDESL 179 Y +PSVTVD ++F + + +L++++IQRG P+ G+WALPGGFV +DESL Sbjct: 7 YPKPSVTVDCVVFGLD----------ATHTLKMMLIQRGVEPFKGEWALPGGFVRLDESL 56 Query: 180 EDAALRELYSETNIDNVYMEQLYTWGDVGRDPRMRVISSSYIALVDRKTLDVQXXXXXXX 239 E+AA+REL ET ++ +++EQLYT+G RDPR RVI+ +Y AL++ + + Sbjct: 57 EEAAMRELREETGVEKIFLEQLYTFGAPDRDPRDRVITVAYYALINLEDHPIHAQTDADA 116 Query: 240 XXWFEVTYDVLESGRRELAEGYMEEQKIRITLQKEDVELTGVVTITETVQGHVRRVRREI 299 WF + EL V Sbjct: 117 VAWFSLD------------------------------ELPNV------------------ 128 Query: 300 AENHGFAFDHLKMIQYAIERLRGKVEYTDIIFNLMPPLFTLSELQRVYEIILGRELLAPA 359 AFDH ++I A +RL+GK+ Y I F L+P FTL++LQ++YE ILG +L Sbjct: 129 ------AFDHQQIIDVATQRLQGKLRYEPIGFELLPRKFTLTQLQKLYEQILGTQLDKRN 182 Query: 360 FRRKI--ADSVTETEEFTKDAGHRPSKLYRYRADKGSR 395 FRRKI D + + E HR ++LY + K R Sbjct: 183 FRRKILKMDLLIKLHELQTGVAHRAARLYSFDEAKYQR 220 >ref|ZP_00019201.1| hypothetical protein [Chloroflexus aurantiacus] Length = 242 Score = 153 bits (386), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 100/281 (35%), Positives = 152/281 (54%), Gaps = 65/281 (23%) Query: 115 YDAGMYERPSVTVDMLIFTVMEQEQDNYRKLSEKSLQLLMIQRGEHPYLGQWALPGGFVG 174 YD Y+ P+VTVD++IF+++ ++L +L++QR P+ G+WA+PGGF+ Sbjct: 9 YDISKYQLPAVTVDVVIFSLIN-----------RTLHVLLVQRKRWPFEGRWAIPGGFIR 57 Query: 175 VDESLEDAALRELYSETNIDNVYMEQLYTWGDVGRDPRMRVISSSYIALVDRKTLDVQXX 234 +DESLE+AA REL ET + +VY+EQLYT+GDV RDPR RVIS +YIALV Sbjct: 58 LDESLEEAARRELEEETGVRDVYLEQLYTFGDVQRDPRHRVISVAYIALVR--------- 108 Query: 235 XXXXXXXWFEVTYDVLESGRRELAEGYMEEQKIRITLQKEDVELTGVVTITETVQGHVRR 294 + Q IR++ + DV V + + Sbjct: 109 ---------------------------ADAQTIRVSAENSDVRWFPVDHLPTPL------ 135 Query: 295 VRREIAENHGFAFDHLKMIQYAIERLRGKVEYTDIIFNLMPPLFTLSELQRVYEIILGRE 354 AFDH +++ YA+ RLR K+EYT + F L+P LF++ EL+ +YE ILG + Sbjct: 136 -----------AFDHDQILAYALSRLRSKLEYTTLAFQLLPELFSILELKHIYEQILGEK 184 Query: 355 LLAPAFRRKIADS-VTETEEFTKDAGHRPSKLYRYRADKGS 394 L F RKI ++ + E + ++ RP++L+R+R D+ Sbjct: 185 LDKGNFYRKIKEAGILEETPYMREGRGRPTRLWRFRRDRSG 225 >ref|ZP_00047746.1| COG1051: ADP-ribose pyrophosphatase [Magnetospirillum magnetotacticum] Length = 243 Score = 131 bits (330), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 87/260 (33%), Positives = 132/260 (50%), Gaps = 52/260 (20%) Query: 107 TEEQFLQAYDAGMYERPSVTVDMLIFTVMEQEQDNYRKLSEKSLQLLMIQRGEHPYLGQW 166 +E FL YD Y RP++TVD+++ L +L+++R EHP+ G+ Sbjct: 19 SEAAFLARYDPADYARPALTVDLVLL-----------GLQGGQPAVLLVKRAEHPHAGRH 67 Query: 167 ALPGGFVGVDESLEDAALRELYSETNIDNVYMEQLYTWGDVGRDPRMRVISSSYIALVDR 226 ALPGGFVG+ E+L+DAA R L + ++EQLYT+G V RDPRMR+++ +Y+AL+ Sbjct: 68 ALPGGFVGIGEALDDAAGRVLREKAGAPPAHLEQLYTFGAVNRDPRMRIVTVAYLALLTE 127 Query: 227 KTLDVQXXXXXXXXXWFEVTY--DVLESGRRELAEGYMEEQKIRITLQKEDVELTGVVTI 284 EV L+ GR +A + E +T+ E V+T+ Sbjct: 128 AAFT-------------EVLARTPALQPGR--VAVPWAGEAGGPVTVLSAGGE---VLTL 169 Query: 285 TETVQGHVRRVRREIAENHGFAFDHLKMIQYAIERLRGKVEYTDIIFNLMPPLFTLSELQ 344 AFDH +++ A+ RLRGK++YT++ F L+ LFTL +LQ Sbjct: 170 ---------------------AFDHAEIVALAMLRLRGKLDYTEVGFALLTDLFTLRQLQ 208 Query: 345 RVYEIILGRELLAPAFRRKI 364 V E ILG+ RR++ Sbjct: 209 DVNEEILGKPPQEAGLRRRM 228 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.321 0.138 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 446,585,193 Number of extensions: 20164796 Number of successful extensions: 39612 Number of sequences better than 1.0e-05: 91 Number of HSP's gapped: 39556 Number of HSP's successfully gapped: 113 Length of query: 395 Length of database: 757,237,578 Length adjustment: 128 Effective length of query: 267 Effective length of database: 409,704,906 Effective search space: 109391209902 Effective search space used: 109391209902 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 127 (53.5 bits)