BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0567.0020.p (334 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_244780.1| two-component sensor histidine kinase [Bacillus... 394 e-108 ref|NP_390917.1| similar to two-component sensor histidine kinas... 364 2e-99 ref|NP_691753.1| two-component sensor histidine kinase [Oceanoba... 342 6e-93 dbj|BAA75355.1| similar to B.subtilis ytsB gene(64%-identity) [B... 339 5e-92 ref|NP_763983.1| putative two-component sensor histidine kinase ... 231 2e-59 >ref|NP_244780.1| two-component sensor histidine kinase [Bacillus halodurans] sp|Q9K620|BCES_BACHD Sensor protein bceS pir||H84138 two-component sensor histidine kinase BH3912 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07631.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 334 Score = 394 bits (1012), Expect = e-108, Method: Compositional matrix adjust. Identities = 188/334 (56%), Positives = 244/334 (73%) Query: 1 MIRKYIKEKLSWXXXXXXXXXXXXXVAYVDSSIPFLSVLYIVVLNIMVCTTFVFLRYHKE 60 MI+ +IKE+ SW +AY+DS+IP V Y V L+ M+ F+ +RY KE Sbjct: 1 MIKTFIKERGSWILIIIFLQCFTVFIAYLDSAIPLAPVFYSVFLSSMIFLFFLAVRYKKE 60 Query: 61 TRFYQRMGAWDEVYDLSTFKEANSPFERMVQEAVNAQTERYRRESSANFQLLEQEKDDLL 120 T FY+++ WD+ D++ A SPFER++++ + QT + ++ + LEQEKDDLL Sbjct: 61 TTFYRKLEEWDKDLDVTNLAAAESPFERIIEQTIVKQTGYLQEKAHRHETALEQEKDDLL 120 Query: 121 SWIHEVKTPLTAMQLMIERLTDETLKPKLMYEWLRVHHLLDQQLHQKRIPFMRNDLYIEM 180 +WIHE+KTPLTAM L+I+RL D T+K +L YEW+R+H LLDQQLHQKRIPFM NDLY+E Sbjct: 121 AWIHEIKTPLTAMHLIIDRLEDRTIKGQLTYEWMRIHLLLDQQLHQKRIPFMENDLYVEK 180 Query: 181 IRLEPVLNKEIQALKSWCIPKGIGFDVDLAVEAVLTDGKWLGFILRQLLTNAVKYSENSD 240 + LE VL++EI+ L+SWCI KGIGFD+ L V VLTD KWL FILRQLL+NAVKYSE SD Sbjct: 181 VNLESVLHQEIKTLQSWCIQKGIGFDLQLEVTDVLTDAKWLSFILRQLLSNAVKYSEASD 240 Query: 241 ILIQSREKAGHTVLIIEDHGRGIDPKDLPRIYDKGFTSTTGRQEGAATGMGLYLTKQVAE 300 I+I+S +G TV+ + D GRGI+PKDLPRI++KGFTST Q ATGMGLYL K+VAE Sbjct: 241 IIIKSDVVSGKTVVEVTDFGRGIEPKDLPRIFEKGFTSTKTDQTNGATGMGLYLAKRVAE 300 Query: 301 PLQIGIHADSMLGEGTTFTLTFPRKNDFLRITGM 334 PL I + S +GEGTTFTLTFP++N+F+R GM Sbjct: 301 PLLIDLAVSSTVGEGTTFTLTFPKENEFVRTLGM 334 >ref|NP_390917.1| similar to two-component sensor histidine kinase [YtsA] [Bacillus subtilis] sp|O35044|BCES_BACSU Sensor protein bceS pir||H70000 two-component sensor histidine kinase homolog ytsB - Bacillus subtilis gb|AAC00254.1| signal transduction protein kinase [Bacillus subtilis] emb|CAB15017.1| ytsB [Bacillus subtilis subsp. subtilis str. 168] Length = 334 Score = 364 bits (934), Expect = 2e-99, Method: Compositional matrix adjust. Identities = 173/328 (52%), Positives = 232/328 (70%) Query: 1 MIRKYIKEKLSWXXXXXXXXXXXXXVAYVDSSIPFLSVLYIVVLNIMVCTTFVFLRYHKE 60 MI+ ++ E+ SW +A+VD SI F +VLY+V L I+ F++ RY KE Sbjct: 1 MIKAFLIERRSWIAAFLFQQALMLFIAFVDPSISFGNVLYMVYLCILFFIIFLWFRYRKE 60 Query: 61 TRFYQRMGAWDEVYDLSTFKEANSPFERMVQEAVNAQTERYRRESSANFQLLEQEKDDLL 120 T FY+ + W+ D++ E +PFE MV+ ++ QTE ++ ++ + LE EKD+L+ Sbjct: 61 TAFYKSLKTWENNLDVTAINEPETPFEAMVERSIAGQTEHLKQTAARHRLALENEKDELM 120 Query: 121 SWIHEVKTPLTAMQLMIERLTDETLKPKLMYEWLRVHHLLDQQLHQKRIPFMRNDLYIEM 180 +WIHEVKTPLTAM L+I+R+ ++ LK +L YEWLR+H LLDQQLHQKRI F+ NDL +E Sbjct: 121 AWIHEVKTPLTAMHLIIDRMEEKALKSQLSYEWLRIHLLLDQQLHQKRISFIENDLSVEF 180 Query: 181 IRLEPVLNKEIQALKSWCIPKGIGFDVDLAVEAVLTDGKWLGFILRQLLTNAVKYSENSD 240 I+L+P++ KEI+ L+SWCI KGIGFD+ L + VL+D KWL FI+RQLLTNAVKYSE S+ Sbjct: 181 IQLQPLIFKEIKDLQSWCIQKGIGFDIQLEAKEVLSDAKWLAFIIRQLLTNAVKYSEASE 240 Query: 241 ILIQSREKAGHTVLIIEDHGRGIDPKDLPRIYDKGFTSTTGRQEGAATGMGLYLTKQVAE 300 I I+S +K T L ++D GRGIDPKD+PRI+DKGFTSTT + A+TGMGLYL K+ A Sbjct: 241 IEIKSFQKGEQTQLQVKDCGRGIDPKDVPRIFDKGFTSTTDHHDQASTGMGLYLAKKAAA 300 Query: 301 PLQIGIHADSMLGEGTTFTLTFPRKNDF 328 PL I I +S G GT FTLTFP +N F Sbjct: 301 PLLIHIDVESEFGAGTVFTLTFPIRNQF 328 >ref|NP_691753.1| two-component sensor histidine kinase [Oceanobacillus iheyensis HTE831] dbj|BAC12788.1| two-component sensor histidine kinase [Oceanobacillus iheyensis HTE831] Length = 334 Score = 342 bits (877), Expect = 6e-93, Method: Compositional matrix adjust. Identities = 165/334 (49%), Positives = 224/334 (67%) Query: 1 MIRKYIKEKLSWXXXXXXXXXXXXXVAYVDSSIPFLSVLYIVVLNIMVCTTFVFLRYHKE 60 MI Y+KE++SW V Y+D +IP S+ YIV + ++ F+ +RY KE Sbjct: 1 MIFSYLKERISWIILFIVLQVITLIVGYMDMTIPMKSIYYIVFIQFVIGIIFLCIRYRKE 60 Query: 61 TRFYQRMGAWDEVYDLSTFKEANSPFERMVQEAVNAQTERYRRESSANFQLLEQEKDDLL 120 T+FY+ + W V DL E ++ F ++V A+ Q++ YR+E + +++EKDDLL Sbjct: 61 TKFYKELMEWKPVIDLIDMPEGDTIFSKIVTRALEDQSQIYRKEYTQLQLDVQREKDDLL 120 Query: 121 SWIHEVKTPLTAMQLMIERLTDETLKPKLMYEWLRVHHLLDQQLHQKRIPFMRNDLYIEM 180 WIHEVKTPLT MQLM+ER+ + L+ +L YEWLR+H LLDQQLHQ+RIPFM+NDLYIE Sbjct: 121 VWIHEVKTPLTTMQLMLERVEGKELRAQLSYEWLRIHLLLDQQLHQRRIPFMKNDLYIEN 180 Query: 181 IRLEPVLNKEIQALKSWCIPKGIGFDVDLAVEAVLTDGKWLGFILRQLLTNAVKYSENSD 240 + L+ ++N+EI+ L+SWC+ KGIGF ++L V +L+D KWL FILRQ++TNAVKYSEN+D Sbjct: 181 VDLQSIINEEIRTLRSWCMQKGIGFQIELNVTQILSDAKWLHFILRQIITNAVKYSENND 240 Query: 241 ILIQSREKAGHTVLIIEDHGRGIDPKDLPRIYDKGFTSTTGRQEGAATGMGLYLTKQVAE 300 I I+S L I D GRGI KDLPRI++KGFTST + ++GMGLYL Q A+ Sbjct: 241 ITIESLVINNQHTLQISDKGRGISAKDLPRIFEKGFTSTKEHFDQGSSGMGLYLAVQAAD 300 Query: 301 PLQIGIHADSMLGEGTTFTLTFPRKNDFLRITGM 334 L I I S GT F L FP+KN+ L +T M Sbjct: 301 SLGIRIEVTSEWSRGTCFQLIFPKKNELLHLTSM 334 >dbj|BAA75355.1| similar to B.subtilis ytsB gene(64%-identity) [Bacillus halodurans] Length = 261 Score = 339 bits (869), Expect = 5e-92, Method: Compositional matrix adjust. Identities = 160/260 (61%), Positives = 202/260 (77%) Query: 75 DLSTFKEANSPFERMVQEAVNAQTERYRRESSANFQLLEQEKDDLLSWIHEVKTPLTAMQ 134 D++ A SPFER++++ + QT + ++ + LEQEKDDLL+WIHE+KTPLTAM Sbjct: 2 DVTNLAAAESPFERIIEQTIVKQTGYLQEKAHRHETALEQEKDDLLAWIHEIKTPLTAMH 61 Query: 135 LMIERLTDETLKPKLMYEWLRVHHLLDQQLHQKRIPFMRNDLYIEMIRLEPVLNKEIQAL 194 L+I+RL D T+K +L YEW+R+H LLDQQLHQKRIPFM NDLY+E + LE VL++EI+ L Sbjct: 62 LIIDRLEDRTIKGQLTYEWMRIHLLLDQQLHQKRIPFMENDLYVEKVNLESVLHQEIKTL 121 Query: 195 KSWCIPKGIGFDVDLAVEAVLTDGKWLGFILRQLLTNAVKYSENSDILIQSREKAGHTVL 254 +SWCI KGIGFD+ L V VLTD KWL FILRQLL+NAVKYSE SDI+I+S +G TV+ Sbjct: 122 QSWCIQKGIGFDLQLEVTDVLTDAKWLSFILRQLLSNAVKYSEASDIIIKSDVVSGKTVV 181 Query: 255 IIEDHGRGIDPKDLPRIYDKGFTSTTGRQEGAATGMGLYLTKQVAEPLQIGIHADSMLGE 314 + D GRGI+PKDLPRI++KGFTST Q ATGMGLYL K+VAEPL I + S +GE Sbjct: 182 EVTDFGRGIEPKDLPRIFEKGFTSTKTDQTNGATGMGLYLAKRVAEPLLIDLAVSSTVGE 241 Query: 315 GTTFTLTFPRKNDFLRITGM 334 GTTFTLTFP++N+F+R GM Sbjct: 242 GTTFTLTFPKENEFVRTLGM 261 >ref|NP_763983.1| putative two-component sensor histidine kinase [Staphylococcus epidermidis ATCC 12228] gb|AAO04025.1| putative two-component sensor histidine kinase [Staphylococcus epidermidis ATCC 12228] Length = 346 Score = 231 bits (588), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 121/332 (36%), Positives = 199/332 (59%), Gaps = 13/332 (3%) Query: 5 YIKEKLSWXXXXXXXXXXXXXVAYVDSSIPFLSVLYIVVLNIMVCTTFVFLRYHKETRFY 64 +IK +++W VAY+D I SV YIV+LN+ + F+ + KE R Sbjct: 10 FIKSRINWILWILFLNIILLGVAYIDYEISVESVFYIVILNVGLSILFLLFTFVKEVRLS 69 Query: 65 QRMGAWDEVYDLSTFKEANSPFERMVQEAVNAQTERYRRESSANFQLLEQE------KDD 118 + E+ ++ A +PF++ V + + YR ++ +++EQ+ + Sbjct: 70 KHFYEDKEIEEIKHKDLAETPFQQQVIDYL------YRHIAAQKEKVVEQQLQIKNHEQT 123 Query: 119 LLSWIHEVKTPLTAMQLMIERLTDETLKPKLMYEWLRVHHLLDQQLHQKRIPFMRNDLYI 178 + ++H++KTP+TAM+L+I++ D+ K L++EW R++ +LD+QL+ R+ D+Y Sbjct: 124 ITEFVHDIKTPVTAMKLLIDQENDDQRKRALLFEWSRINEMLDKQLYLTRLETHHRDMYF 183 Query: 179 EMIRLEPVLNKEIQALKSWCIPKGIGFDVDLAVE-AVLTDGKWLGFILRQLLTNAVKYSE 237 + I L+ ++ EIQ + KGIGF++D E V TD KW ++RQ+L+N++KYS+ Sbjct: 184 DYISLKRMVIDEIQVTRHISQAKGIGFELDFKDEQKVYTDVKWCRMMIRQVLSNSLKYSD 243 Query: 238 NSDILIQSREKAGHTVLIIEDHGRGIDPKDLPRIYDKGFTSTTGRQEGAATGMGLYLTKQ 297 NS I + GH VL I+D+GRGI +DLPRI+D+GFTSTT R + A++GMGLYL + Sbjct: 244 NSTINLSGYNIEGHVVLKIKDYGRGISKRDLPRIFDRGFTSTTDRNDTASSGMGLYLVQS 303 Query: 298 VAEPLQIGIHADSMLGEGTTFTLTFPRKNDFL 329 V E L I + DS++G+GTTF FP++N+ + Sbjct: 304 VKEQLGIEVKVDSIVGKGTTFYFIFPQQNEII 335 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.322 0.138 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 454,234,978 Number of extensions: 18004443 Number of successful extensions: 57551 Number of sequences better than 1.0e-05: 1392 Number of HSP's gapped: 58026 Number of HSP's successfully gapped: 1395 Length of query: 334 Length of database: 757,237,578 Length adjustment: 126 Effective length of query: 208 Effective length of database: 415,135,104 Effective search space: 86348101632 Effective search space used: 86348101632 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 126 (53.1 bits)