BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0567.0012.p (335 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_635076.1| oxidoreductase [Methanosarcina mazei Goe1] >gi|... 205 2e-51 ref|NP_633204.1| oxidoreductase [Methanosarcina mazei Goe1] >gi|... 189 5e-47 gb|EAK79341.1| unknown [environmental sequence] 185 1e-45 gb|AAN04236.1| putative bi-domain oxidoreductase [Streptomyces s... 179 1e-43 ref|NP_624709.1| putative bi-domain oxidoreductase [Streptomyces... 176 5e-43 >ref|NP_635076.1| oxidoreductase [Methanosarcina mazei Goe1] gb|AAM32748.1| oxidoreductase [Methanosarcina mazei Goe1] Length = 720 Score = 205 bits (521), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 126/376 (33%), Positives = 190/376 (50%), Gaps = 53/376 (14%) Query: 3 IVAAKEGKVAILQAAIPELNKRHVQVRTEYSGISPGTE---------------------- 40 ++ K+G + + + IP + V VR YS IS GTE Sbjct: 5 VLNLKDGDLTVEEVPIPTIKGSGVLVRNHYSVISAGTESGVVDLADKSLIGKARARPDLA 64 Query: 41 ---LSSIKRSGLSPVS--------------LGYSAVGIVEQTGSEVRDIHPGDRVACYGV 83 ++ K+ G P+S LGYS+ G V +++DI PGDRVAC G Sbjct: 65 MKVINKAKQDG--PISAFQQAMGRLEKREPLGYSSAGTVISVSEDIKDIKPGDRVACAGA 122 Query: 84 PYVRHAEVISVPTNLVTKVPHHVNPEEAAFTGLGAIAIHALRTADVRFXXXXXXXXXXXX 143 Y HA+V+ VP NL KVP +V+ + A FT +G+IA+ +R ADV+ Sbjct: 123 GYANHADVVFVPRNLCAKVPENVDFKNACFTTVGSIAMQGVRNADVKIGENIVVIGLGLI 182 Query: 144 XXXXAQIASAAACHTAAYDLSEDRVQLLQGQMGITSGFSS-----EEEVEHFVMNETGGA 198 QI A+ C DL E +V L + ++G +S EE ++ F + G Sbjct: 183 GLITLQILKASGCRVFGVDLDESKVNLAR-ELGADLSYSRNSPNLEERIKQF----SRGI 237 Query: 199 GFDSILLCAGGPGEVLINKSLEWLRDLGKIVIVGDLSMEFSRDLMFRKEAQILISRAGGP 258 G DS ++ A ++ + + R+ GK+VIVG + M+ R+ + KE ++ ISR+ GP Sbjct: 238 GADSTIITAATRSNDPVDFAGKITRERGKVVIVGLVGMDIPREEYYNKELEMRISRSYGP 297 Query: 259 GRYDMRYEEDNQDYPIGFVRWTEGRNMDEYVRLLAEKRITVSPAITHRFALEEAPAAYGI 318 GRYD YEE QDYP +VRWTE RNM ++ L++ K+I++ P ITH + +E+AP AY I Sbjct: 298 GRYDRNYEEYGQDYPAPYVRWTENRNMQAFLDLISMKKISMEPIITHEYEIEQAPEAYNI 357 Query: 319 YQSGPAQGALATLIKY 334 + + L ++KY Sbjct: 358 IKE--RKPYLGLVLKY 371 >ref|NP_633204.1| oxidoreductase [Methanosarcina mazei Goe1] gb|AAM30876.1| oxidoreductase [Methanosarcina mazei Goe1] Length = 724 Score = 189 bits (481), Expect = 5e-47, Method: Compositional matrix adjust. Identities = 121/358 (33%), Positives = 178/358 (49%), Gaps = 43/358 (12%) Query: 3 IVAAKEGKVAILQAAIPELNKRHVQVRTEYSGISPGTE---------------------- 40 ++ K+G + + IP L V VR YS IS GTE Sbjct: 11 VLNLKDGDLTVEDVPIPTLKGSGVLVRNYYSVISAGTESGLVDLADKSLIGKARARPDLA 70 Query: 41 ---LSSIKRSGLSPVS--------------LGYSAVGIVEQTGSEVRDIHPGDRVACYGV 83 ++ K+ G P+S LGYS+ G V ++ I GDRVAC G Sbjct: 71 MKVINKAKQDG--PISAFQQAMGRLEKREPLGYSSAGTVISVSEDIASIKVGDRVACAGA 128 Query: 84 PYVRHAEVISVPTNLVTKVPHHVNPEEAAFTGLGAIAIHALRTADVRFXXXXXXXXXXXX 143 Y HA+V VP NL KVP +V+ + A FT +G+IA+ +R ADVR Sbjct: 129 GYANHADVAFVPKNLCVKVPDNVDLKNACFTTVGSIAMQGVRNADVRVGENVVVVGLGLI 188 Query: 144 XXXXAQIASAAACHTAAYDLSEDRVQLLQGQMGITSGFS-SEEEVEHFVMNETGGAGFDS 202 QI A+ C DL E +V+L + ++G S + +E V + G G D Sbjct: 189 GLITVQILKASGCRVFGIDLDESKVKLAK-ELGADFALSRNTPNIEESVRQFSRGIGADV 247 Query: 203 ILLCAGGPGEVLINKSLEWLRDLGKIVIVGDLSMEFSRDLMFRKEAQILISRAGGPGRYD 262 ++ A ++ + + R+ GK+VIVG + M+ R+ + KE ++ +SR+ GPGRYD Sbjct: 248 TIIAAATRSNDPVDFAGKITRERGKVVIVGLVGMDIPREEYYNKEIELRVSRSYGPGRYD 307 Query: 263 MRYEEDNQDYPIGFVRWTEGRNMDEYVRLLAEKRITVSPAITHRFALEEAPAAYGIYQ 320 YEE +DYP +VRWTE RNM ++ LL+ K+I++ P I+H FA+E+AP AY I + Sbjct: 308 RAYEEFGRDYPAPYVRWTENRNMQAFLDLLSMKKISMDPIISHEFAIEQAPDAYDIIE 365 >gb|EAK79341.1| unknown [environmental sequence] Length = 301 Score = 185 bits (469), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 99/269 (36%), Positives = 147/269 (54%), Gaps = 5/269 (1%) Query: 50 SPVSLGYSAVGIVEQTGSEVRDIHPGDRVACYGVPYVRHAEVISVPTNLVTKVPHHVNPE 109 +P LGYS+ G V +TG +V PGDRVAC G Y H+E ISVP NL K+P ++ + Sbjct: 6 NPTPLGYSSAGTVTETGKDVHQFSPGDRVACIGSGYASHSEFISVPENLCCKIPENLTMQ 65 Query: 110 EAAFTGLGAIAIHALRTADVRFXXXXXXXXXXXXXXXXAQIASAAACHTAAYDLSEDRVQ 169 +AAF +GAIA++ +R A++ F QI A C A D++ + Sbjct: 66 DAAFGMVGAIALNGIRCANLTFGETVVVIGLGLLGQLTTQILKAYGCKVIAMDINPKK-- 123 Query: 170 LLQGQMGITSGFSSEEEVEHFVMNE--TGGAGFDSILLCAGGPGEVLINKSLEWLRDLGK 227 L + T+ FS + E E T G G D+ ++ I+ SLE ++ G Sbjct: 124 -LGEKNNFTADFSFDSESALIEGTEKITKGYGADAAIITTASSSSGPIDTSLEVIKFKGT 182 Query: 228 IVIVGDLSMEFSRDLMFRKEAQILISRAGGPGRYDMRYEEDNQDYPIGFVRWTEGRNMDE 287 IV+VG + R+ M+ KEAQI++S+A GPG +D YE DYP+ VRWTE RN++E Sbjct: 183 IVLVGTADIHPERNDMWHKEAQIIVSKAAGPGTFDPIYENKGVDYPLSHVRWTENRNLEE 242 Query: 288 YVRLLAEKRITVSPAITHRFALEEAPAAY 316 + L+++++I I+H+F +EEA Y Sbjct: 243 LIHLISKEKINTKNLISHKFKIEEAEDVY 271 >gb|AAN04236.1| putative bi-domain oxidoreductase [Streptomyces sp. 139] Length = 730 Score = 179 bits (453), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 115/365 (31%), Positives = 165/365 (45%), Gaps = 38/365 (10%) Query: 7 KEGKVAILQAAIPELNKRHVQVRTEYSGISPGTELSSIKRSGLS---------------- 50 K G++A+L P V VRT +S IS GTEL + +G+S Sbjct: 9 KSGELALLDVPEPGCKPGGVLVRTAFSLISTGTELMKVSEAGMSMLGKARSRPDQVAKVV 68 Query: 51 --------PVS-------------LGYSAVGIVEQTGSEVRDIHPGDRVACYGVPYVRHA 89 P + LGYS G+VEQ G+ + D+ GD VAC G + HA Sbjct: 69 QSVAANGVPATYRKVMGKLDSYTPLGYSLCGVVEQVGAGIDDVKAGDLVACAGNEHALHA 128 Query: 90 EVISVPTNLVTKVPHHVNPEEAAFTGLGAIAIHALRTADVRFXXXXXXXXXXXXXXXXAQ 149 E+ VP NL VP V P AAF +G+IA+ +R + R Q Sbjct: 129 ELNWVPKNLYVPVPDGVAPRHAAFGTVGSIALQGVRQGESRLGEVALVIGLGLIGQLVVQ 188 Query: 150 IASAAACHTAAYDLSEDRVQLLQGQMGITSGFSSEEEVEHFVMNETGGAGFDSILLCAGG 209 + +A+ D R +L + G VE V TGG G D + L AGG Sbjct: 189 LLNASGVRVVGVDPDPARCELAERLGAAACGDPGSASVESAVAELTGGMGVDQVYLAAGG 248 Query: 210 PGEVLINKSLEWLRDLGKIVIVGDLSMEFSRDLMFRKEAQILISRAGGPGRYDMRYEEDN 269 + + RD G++V +G ++ + + KE + SR+ GPGRYD YE Sbjct: 249 SSNQPVELAARLCRDRGRVVDIGKCRLDLPWNAYYEKELDVRFSRSYGPGRYDPEYELQG 308 Query: 270 QDYPIGFVRWTEGRNMDEYVRLLAEKRITVSPAITHRFALEEAPAAYGIYQSGPAQGALA 329 +DYPIG+VRWTE RN+ ++ L+A R+ V P ++H E+A Y + G + A+A Sbjct: 309 RDYPIGYVRWTERRNLACFLDLIARGRVDVEPLVSHVSGFEDAVETYRRLEDGELK-AVA 367 Query: 330 TLIKY 334 L +Y Sbjct: 368 VLFRY 372 >ref|NP_624709.1| putative bi-domain oxidoreductase [Streptomyces coelicolor A3(2)] emb|CAB58328.1| putative bi-domain oxidoreductase [Streptomyces coelicolor A3(2)] Length = 726 Score = 176 bits (447), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 115/365 (31%), Positives = 167/365 (45%), Gaps = 38/365 (10%) Query: 7 KEGKVAILQAAIPELNKRHVQVRTEYSGISPGTELSSIKRSGLS---------------- 50 K G++A+L +P V VRT YS IS GTEL + +G+S Sbjct: 5 KSGELALLDVPVPGCKPGGVLVRTAYSLISTGTELMKVSEAGMSMLGKARSRPDQVAKVV 64 Query: 51 --------PVS-------------LGYSAVGIVEQTGSEVRDIHPGDRVACYGVPYVRHA 89 P + LGYS G+VEQ G + D+ GD VAC G + HA Sbjct: 65 QSVATNGVPATYRKVMGKLDSYTPLGYSLCGVVEQVGEGIDDVKAGDLVACAGNEHALHA 124 Query: 90 EVISVPTNLVTKVPHHVNPEEAAFTGLGAIAIHALRTADVRFXXXXXXXXXXXXXXXXAQ 149 E+ VP NL VP + +AAF +G+IA+ +R + R Q Sbjct: 125 ELNWVPRNLYAPVPDGLAARDAAFGTVGSIALQGVRQGESRLGETALVIGLGLIGQLVVQ 184 Query: 150 IASAAACHTAAYDLSEDRVQLLQGQMGITSGFSSEEEVEHFVMNETGGAGFDSILLCAGG 209 + A+ D +R +L + G + VE V+ T G G D + L AGG Sbjct: 185 LLVASGVRVVGADPDAERCELAERLGAAACGDPASPAVESAVVELTDGHGVDQVYLAAGG 244 Query: 210 PGEVLINKSLEWLRDLGKIVIVGDLSMEFSRDLMFRKEAQILISRAGGPGRYDMRYEEDN 269 + + RD G++V +G ++ + + KE + SR+ GPGRYD YE + Sbjct: 245 GSNQPVELAARLCRDRGRVVDIGKCRLDLPWNAYYEKELDVRFSRSYGPGRYDPEYELEG 304 Query: 270 QDYPIGFVRWTEGRNMDEYVRLLAEKRITVSPAITHRFALEEAPAAYGIYQSGPAQGALA 329 +DYPIG+VRWTE RN+ ++ L+A R+ V+P IT ++A Y Q G A A+A Sbjct: 305 RDYPIGYVRWTERRNLACFLDLVARGRVDVAPLITRTADFDDAVETYRSLQDG-ALKAVA 363 Query: 330 TLIKY 334 L +Y Sbjct: 364 VLFRY 368 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.318 0.135 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 474,391,192 Number of extensions: 18899885 Number of successful extensions: 44494 Number of sequences better than 1.0e-05: 62 Number of HSP's gapped: 44582 Number of HSP's successfully gapped: 63 Length of query: 335 Length of database: 757,237,578 Length adjustment: 126 Effective length of query: 209 Effective length of database: 415,135,104 Effective search space: 86763236736 Effective search space used: 86763236736 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 126 (53.1 bits)