BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0567.0004.p (341 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value dbj|BAB72059.1| AcrV [Streptomyces galilaeus] 328 1e-88 ref|NP_628013.1| putative ABC-transporter ATP-binding component ... 327 3e-88 sp|P32010|DRRA_STRPE Daunorubicin resistance ATP-binding protein... 324 2e-87 emb|CAA75761.1| ORF1 [Streptomyces rochei] 315 1e-84 ref|NP_827118.1| putative ABC transporter ATP-binding component ... 293 4e-78 >dbj|BAB72059.1| AcrV [Streptomyces galilaeus] Length = 345 Score = 328 bits (841), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 166/312 (53%), Positives = 217/312 (69%) Query: 15 AIEAHGLVKVFGDNRAVDGVDLQVATGSIYGVLGPNGAGKTTAIRMLATLLRPDGGSAKV 74 AIE GLVK FG+ RAVDGVDL + G +YGVLGPNGAGKTT IRMLATLL PDGG+A+V Sbjct: 27 AIETSGLVKSFGETRAVDGVDLAIPQGVVYGVLGPNGAGKTTTIRMLATLLTPDGGTARV 86 Query: 75 FGHDVVKEPQIVRQLIGVTGQYASVDESLSATENLVIFSXXXXXXXXXXXXXXXXXXXXF 134 GHDVV+E + VR + +TGQ+AS+DE L+ATENL + + F Sbjct: 87 LGHDVVREAEAVRSRVSLTGQFASIDEDLTATENLTLLARLLGFSRSQAVERSEELLAAF 146 Query: 135 GLTEAAKRPLKNFSGGMRRRLDLAASLIAQPPLIFLDEPTTGLDPRTRNQMWETIRRLIQ 194 LT+AA R K FSGGMRRRLD+AASL+ P L+FLDEPTTGLDPRTR Q+W+++R ++ Sbjct: 147 DLTKAAGRQSKTFSGGMRRRLDIAASLVITPDLLFLDEPTTGLDPRTRGQVWDSVRAMVA 206 Query: 195 SGSTVLLTTQYLEEADQLADRIAVIDHGHVVAEGTVDELKSSVGTSSLQLRVQNMRDIGI 254 G+T+LLTTQYL+EADQLADRIAVIDHG V+AEGT ELK+SVGT +L +R+ N Sbjct: 207 LGTTILLTTQYLDEADQLADRIAVIDHGRVIAEGTTGELKASVGTGALHVRLVNSESRPE 266 Query: 255 ARQTVERMLRVQTSISAEAAKITAPLGNVDRVADLLIALREAGISLAELSVQKPTLDEVF 314 A Q + R L ++ ++ + +RVA L L ++ I++A+ + +P+LDEVF Sbjct: 267 ASQLLTRALAAPVFQESDPFALSVRTDDSERVAKALTELAQSEIAVADFAFGRPSLDEVF 326 Query: 315 LSITGHGVEEKS 326 L++TG +E + Sbjct: 327 LALTGRPAQEDT 338 >ref|NP_628013.1| putative ABC-transporter ATP-binding component [Streptomyces coelicolor A3(2)] pir||T36505 probable ABC-type transport system ATP-binding component - Streptomyces coelicolor emb|CAB46947.1| putative ABC-transporter ATP-binding component [Streptomyces coelicolor A3(2)] Length = 342 Score = 327 bits (837), Expect = 3e-88, Method: Compositional matrix adjust. Identities = 167/312 (53%), Positives = 216/312 (69%), Gaps = 6/312 (1%) Query: 15 AIEAHGLVKVFGDNRAVDGVDLQVATGSIYGVLGPNGAGKTTAIRMLATLLRPDGGSAKV 74 AIE GLVK FG+ RAVDGVDL V G++YGVLGPNGAGKTT ++MLATLLRPDGG A+V Sbjct: 9 AIETAGLVKTFGETRAVDGVDLAVPAGTVYGVLGPNGAGKTTTVKMLATLLRPDGGHARV 68 Query: 75 FGHDVVKEPQIVRQLIGVTGQYASVDESLSATENLVIFSXXXXXXXXXXXXXXXXXXXXF 134 FGHDVV E VR + +TGQYASVDE L+ TENLV+ F Sbjct: 69 FGHDVVHEADEVRGRVSLTGQYASVDEDLTGTENLVLLGRLLGHGKAAARERGDQLLAAF 128 Query: 135 GLTEAAKRPLKNFSGGMRRRLDLAASLIAQPPLIFLDEPTTGLDPRTRNQMWETIRRLIQ 194 GLT+AA + +K++SGGMRRR+D+AAS++ P L+FLDEPTTGLDPR+RNQ+W+ +R ++ Sbjct: 129 GLTDAAAKQVKHYSGGMRRRIDIAASILNTPDLLFLDEPTTGLDPRSRNQVWDIVRAVVA 188 Query: 195 SGSTVLLTTQYLEEADQLADRIAVIDHGHVVAEGTVDELKSSVGTSSLQLRVQNMRDIGI 254 G+TVLLTTQYL+EADQLA RIAVID G V+AEGT ELK+SVG S+ LR+++ + Sbjct: 189 QGTTVLLTTQYLDEADQLASRIAVIDKGRVIAEGTKGELKASVGAGSVHLRLRDAEERPE 248 Query: 255 ARQTVERMLRVQTSISAEAAKITAPLG------NVDRVADLLIALREAGISLAELSVQKP 308 A + + +L + + +TA LG D+ A L L AGI++ S+ +P Sbjct: 249 AERVLRNLLVAEVQPEPDPVALTARLGAAASDTAADQAAKALGELARAGITVDSFSLGQP 308 Query: 309 TLDEVFLSITGH 320 +LDEVFL++TGH Sbjct: 309 SLDEVFLALTGH 320 >sp|P32010|DRRA_STRPE Daunorubicin resistance ATP-binding protein drrA pir||S27707 daunorubicin resistance protein - Streptomyces peucetius gb|AAA74717.1| daunorubicin resistance protein Length = 330 Score = 324 bits (830), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 168/320 (52%), Positives = 220/320 (68%), Gaps = 16/320 (5%) Query: 15 AIEAHGLVKVFGDNRAVDGVDLQVATGSIYGVLGPNGAGKTTAIRMLATLLRPDGGSAKV 74 AIE GLVKV+ RAVDG+DL V G +YG+LGPNGAGK+T IRMLATLLRPDGG+A+V Sbjct: 8 AIETSGLVKVYNGTRAVDGLDLNVPAGLVYGILGPNGAGKSTTIRMLATLLRPDGGTARV 67 Query: 75 FGHDVVKEPQIVRQLIGVTGQYASVDESLSATENLVIFSXXXXXXXXXXXXXXXXXXXXF 134 FGHDV EP VR+ I VTGQYASVDE L+ TENLV+ F Sbjct: 68 FGHDVTSEPDTVRRRISVTGQYASVDEGLTGTENLVMMGRLQGYSWARARERAAELIDGF 127 Query: 135 GLTEAAKRPLKNFSGGMRRRLDLAASLIAQPPLIFLDEPTTGLDPRTRNQMWETIRRLIQ 194 GL +A R LK +SGGMRRRLD+AAS++ P L+FLDEPTTGLDPR+RNQ+W+ +R L+ Sbjct: 128 GLGDARDRLLKTYSGGMRRRLDIAASIVVTPDLLFLDEPTTGLDPRSRNQVWDIVRALVD 187 Query: 195 SGSTVLLTTQYLEEADQLADRIAVIDHGHVVAEGTVDELKSSVGTSSLQLRVQNMRDIGI 254 +G+TVLLTTQYL+EADQLADRIAVIDHG V+AEGT ELKSS+G++ L+LR+ + + Sbjct: 188 AGTTVLLTTQYLDEADQLADRIAVIDHGRVIAEGTTGELKSSLGSNVLRLRLHDAQ---- 243 Query: 255 ARQTVERMLRVQTSI--------SAEAAKITAPLGNVDRVADLLIALREAGISLAELSVQ 306 +R ER+L + + +A +A+I P + +A+ L + + S+ Sbjct: 244 SRAEAERLLSAELGVTIHRDSDPTALSARIDDPRQGMRALAE----LSRTHLEVRSFSLG 299 Query: 307 KPTLDEVFLSITGHGVEEKS 326 + +LDEVFL++TGH +++S Sbjct: 300 QSSLDEVFLALTGHPADDRS 319 >emb|CAA75761.1| ORF1 [Streptomyces rochei] Length = 363 Score = 315 bits (806), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 162/315 (51%), Positives = 219/315 (69%), Gaps = 7/315 (2%) Query: 11 SKDWAIEAHGLVKVFGDNRAVDGVDLQVATGSIYGVLGPNGAGKTTAIRMLATLLRPDGG 70 S + AIE GLVKVFG+NRAVDGVDL+V G++YG+LGPNGAGKTT +++LATLLRPDGG Sbjct: 2 STELAIETTGLVKVFGENRAVDGVDLRVPAGTVYGLLGPNGAGKTTTVKVLATLLRPDGG 61 Query: 71 SAKVFGHDVVKEPQIVRQLIGVTGQYASVDESLSATENLVIFSXXXXXXXXXXXXXXXXX 130 A+VFG DV+ + VR + +TGQYASVDE L+ TENL++ + Sbjct: 62 EARVFGRDVLADADAVRGRVSLTGQYASVDEDLTGTENLLLLARLLGHSKPAARERAAQL 121 Query: 131 XXXFGLTEAAKRPLKNFSGGMRRRLDLAASLIAQPPLIFLDEPTTGLDPRTRNQMWETIR 190 FGL+EAA R +K++SGGMRRR+D+AAS++ P L+FLDEPTTGLDPR+RNQ+W+ +R Sbjct: 122 LDAFGLSEAAGRQVKSYSGGMRRRIDIAASILNTPDLLFLDEPTTGLDPRSRNQVWDIVR 181 Query: 191 RLIQSGSTVLLTTQYLEEADQLADRIAVIDHGHVVAEGTVDELKSSVGTSSLQLRVQNMR 250 ++ G+TVLLTTQYL+EADQLA RIAVIDHG V+AEGT ELK+SVG+ ++ LR++ Sbjct: 182 AVVAQGTTVLLTTQYLDEADQLASRIAVIDHGRVIAEGTKGELKASVGSGAVHLRLREAE 241 Query: 251 DIGIARQTVERMLRVQTSISAEAAKITA-------PLGNVDRVADLLIALREAGISLAEL 303 A + + L + A+ +TA LG ++ A L L AGI++ Sbjct: 242 QRPEAERILALALNATVQLDADPVALTARVNGHGTELGAAEQAARALSELARAGITVDNF 301 Query: 304 SVQKPTLDEVFLSIT 318 ++ +P+LDEVFL++T Sbjct: 302 ALGQPSLDEVFLALT 316 >ref|NP_827118.1| putative ABC transporter ATP-binding component [Streptomyces avermitilis MA-4680] dbj|BAC73653.1| putative ABC transporter ATP-binding component [Streptomyces avermitilis MA-4680] Length = 346 Score = 293 bits (750), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 151/327 (46%), Positives = 216/327 (66%), Gaps = 5/327 (1%) Query: 15 AIEAHGLVKVFGDNRAVDGVDLQVATGSIYGVLGPNGAGKTTAIRMLATLLRPDGGSAKV 74 A+ GLVK +G+ +A+DGVDL+V G++ GVLGPNGAGKTT +R L+TL+ PD G A V Sbjct: 18 AVVVRGLVKHYGETKALDGVDLEVREGTVLGVLGPNGAGKTTLVRCLSTLITPDSGHAVV 77 Query: 75 FGHDVVKEPQIVRQLIGVTGQYASVDESLSATENLVIFSXXXXXXXXXXXXXXXXXXXXF 134 G+DVVK+P+ R++IG+TGQYASVDE LS ENL + F Sbjct: 78 AGYDVVKQPRGTRRVIGLTGQYASVDEKLSGYENLYLIGRLLDLPRKEARARADGLLERF 137 Query: 135 GLTEAAKRPLKNFSGGMRRRLDLAASLIAQPPLIFLDEPTTGLDPRTRNQMWETIRRLIQ 194 LT+AAKRP +SGGMRRRLDLAAS++ +P +++LDEPTTGLDPRTRN++W ++R++ Sbjct: 138 SLTDAAKRPASTYSGGMRRRLDLAASMMGRPSVLYLDEPTTGLDPRTRNEVWTEVKRMVA 197 Query: 195 SGSTVLLTTQYLEEADQLADRIAVIDHGHVVAEGTVDELKSSVGTSSLQLRVQN---MRD 251 G+TVLLTTQY+EEA+QLA + VID G V+A G +DELK+ VG +L++R + +R Sbjct: 198 EGATVLLTTQYMEEAEQLASELTVIDRGKVIAGGRIDELKARVGGRTLRVRPADPLELRP 257 Query: 252 IGIARQTVERMLRVQTSISAEAAKITAPLGNVDRVADLLIALREAGISLAELSVQKPTLD 311 A ++ E + P+ + +++ ++ A+ GI+LA ++ + P+LD Sbjct: 258 TAAALDDFGLTGPGSATVDPETGTVVVPILSDEQLTAVVGAVTARGITLAGITTELPSLD 317 Query: 312 EVFLSITGH--GVEEKSAPASAEFIQA 336 VFLS+TGH + ++PAS EF +A Sbjct: 318 AVFLSLTGHKASAPQDASPASPEFAKA 344 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.316 0.132 0.364 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 429,630,424 Number of extensions: 15776206 Number of successful extensions: 119217 Number of sequences better than 1.0e-05: 14102 Number of HSP's gapped: 108538 Number of HSP's successfully gapped: 14824 Length of query: 341 Length of database: 757,237,578 Length adjustment: 126 Effective length of query: 215 Effective length of database: 415,135,104 Effective search space: 89254047360 Effective search space used: 89254047360 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 126 (53.1 bits)