BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0566.0023.p (228 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00103861.1| COG0745: Response regulators consisting of a ... 205 6e-52 ref|ZP_00061961.1| COG0745: Response regulators consisting of a ... 203 2e-51 ref|NP_657731.1| REC, cheY-homologous receiver domain [Bacillus ... 200 3e-50 ref|NP_977734.1| DNA-binding response regulator [Bacillus cereus... 199 3e-50 ref|NP_655198.1| REC, cheY-homologous receiver domain [Bacillus ... 196 4e-49 >ref|ZP_00103861.1| COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Desulfitobacterium hafniense] Length = 233 Score = 205 bits (522), Expect = 6e-52, Method: Compositional matrix adjust. Identities = 101/225 (44%), Positives = 149/225 (66%), Gaps = 1/225 (0%) Query: 3 RILIIDDEVALVLLLTDELQAKGHEVLAAYDGNEGVRLAD-SEPDLVILDIMMPGMNGFE 61 +ILI DDEV L L+ D L + +E L A DG+E + L ++P LVILDIMMPG++G E Sbjct: 5 KILIADDEVELAELVKDFLSDEQYEALVARDGHEALELFRMNQPQLVILDIMMPGLDGME 64 Query: 62 VCRSIRDRVSCPIIFLSARQSEADRVRGLTLGGDDYVIKPFGLRELLARIEANLRREERS 121 VCR IR + PII LSA+++E D++ GL LG DDY++KPF E++AR++A LRR + S Sbjct: 65 VCRRIRAESNVPIIMLSAKKAEVDKILGLGLGADDYIVKPFSPGEVVARVKAQLRRFKMS 124 Query: 122 RQKPQQQSRLRFGKLELSLKERLVSVAGEPVALTRREYEITELLALHGGQVFSREHIYEK 181 + L + LE+ ++ ++AG P+ LT +E+E+ LALH QV +RE I+ Sbjct: 125 AVPEPKTRLLSYSGLEIDVQGYEAALAGRPLELTTKEFELLRFLALHPNQVLTREQIFAN 184 Query: 182 VWGYDAEGDASTVVEHVKKIRAKLAAADPSGDYISTVWGIGYKWT 226 VWG++ GD +TV H+KK+R K+ + + +I TVWG+GYK++ Sbjct: 185 VWGFNESGDLNTVTVHIKKLREKIESDLANPTFIKTVWGVGYKFS 229 >ref|ZP_00061961.1| COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Clostridium thermocellum ATCC 27405] Length = 235 Score = 203 bits (517), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 105/228 (46%), Positives = 151/228 (66%), Gaps = 4/228 (1%) Query: 2 SRILIIDDEVALVLLLTDELQAKGHEVLAAYDGNEGVRLADSE-PDLVILDIMMPGMNGF 60 ++IL++DDE +V +L L +G L A DG + + LA SE PDL++LDIM+P ++GF Sbjct: 6 AKILVVDDEKNIVDILKFNLAKEGFSTLEANDGEQAIELALSEKPDLILLDIMLPKLDGF 65 Query: 61 EVCRSIRDRVSCPIIFLSARQSEADRVRGLTLGGDDYVIKPFGLRELLARIEANLRREER 120 VCR +R+ +S PII ++A++ E D+V GL LG DDY+ KPF REL+AR++ANLRR Sbjct: 66 TVCRKLRESISTPIIMITAKEEEVDKVLGLELGADDYITKPFSTRELMARVKANLRRVAS 125 Query: 121 SRQKPQQQSR-LRFGKLELSLKERLVSVAGEPVALTRREYEITELLALHGGQVFSREHIY 179 S + ++QS L+FG LE+ ++ V E + LT RE+E+ + LAL GQ+FSRE + Sbjct: 126 SAETQKKQSNYLKFGDLEIDIEHYEVRRNNEVIELTLREFELVKFLALQPGQIFSRETLL 185 Query: 180 EKVWGYDAEGDASTVVEHVKKIRAKLAAADPSGD-YISTVWGIGYKWT 226 EKVWGY+ GD TV V+++R K+ DPS YI T G+GY + Sbjct: 186 EKVWGYEYYGDVRTVDVTVRRVREKI-EKDPSNPCYIMTKRGVGYYFN 232 >ref|NP_657731.1| REC, cheY-homologous receiver domain [Bacillus anthracis A2012] ref|NP_846147.1| lantibiotic biosynthesis DNA-binding response regulator, putative [Bacillus anthracis str. Ames] gb|AAP27633.1| lantibiotic biosynthesis DNA-binding response regulator, putative [Bacillus anthracis str. Ames] Length = 220 Score = 200 bits (508), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 106/227 (46%), Positives = 144/227 (63%), Gaps = 11/227 (4%) Query: 1 VSRILIIDDEVALVLLLTDELQAKGHEVLAAYDGNEGVRLADSEPDLVILDIMMPGMNGF 60 ++RIL IDDE ++ ++ L+ +GHEV A + + DL++LD+MMP ++GF Sbjct: 1 MARILAIDDEDGILYIIKSALEKEGHEVTAVSNPLTIPKEKFCHYDLILLDVMMPEIDGF 60 Query: 61 EVCRSIRDRVSCPIIFLSARQSEADRVRGLTLGGDDYVIKPFGLRELLARIEANLRREER 120 +C+ IRD V PI+FL+A+ E D + GL+LGGDDY+ KPFG+ EL AR+ A++RRE R Sbjct: 61 TLCKEIRDFVDSPIVFLTAKTMEKDLITGLSLGGDDYITKPFGIGELRARVSAHVRREHR 120 Query: 121 SRQKPQQQSRLRFGKLELSLKERLVSVAGEPVALTRREYEITELLALHGGQVFSREHIYE 180 +Q S L F LS KE + +A T+ EY I E LAL+ GQVFSRE IYE Sbjct: 121 EKQNAFFLSGLTF---HLSCKE--IWYDDTSIAFTKSEYGICEYLALNHGQVFSREKIYE 175 Query: 181 KVWGYDAEGDASTVVEHVKKIRAKLA--AADPSGDYISTVWGIGYKW 225 V+GY+ E D +VEH+K IR KL+ +P I TVWGIGYKW Sbjct: 176 NVFGYEGESDNQVIVEHIKNIRHKLSKYGMNP----IETVWGIGYKW 218 >ref|NP_977734.1| DNA-binding response regulator [Bacillus cereus ATCC 10987] gb|AAS40342.1| DNA-binding response regulator [Bacillus cereus ATCC 10987] Length = 223 Score = 199 bits (507), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 104/224 (46%), Positives = 142/224 (63%), Gaps = 8/224 (3%) Query: 3 RILIIDDEVALVLLLTDELQAKGHEVLAAYDGNEGVR-LADSEPDLVILDIMMPGMNGFE 61 R+L++DDE + L+ L G+E A +G E ++ L + D V+LDIMMP M+G Sbjct: 5 RVLVVDDESDMRQLVGMYLDNFGYEWGEAENGKEALKKLETNHYDFVVLDIMMPEMDGLS 64 Query: 62 VCRSIRDRVSCPIIFLSARQSEADRVRGLTLGGDDYVIKPFGLRELLARIEANLRREERS 121 VC+ IR PIIFL+A+ E +RV GL +G DDY++KPF EL+AR+EA LRR Sbjct: 65 VCKEIRKTSDVPIIFLTAKGEEWNRVNGLRMGADDYIVKPFSPGELIARMEAVLRR---- 120 Query: 122 RQKPQQQSRLRFGKLELSLKERLVSVAGEPVALTRREYEITELLALHGGQVFSREHIYEK 181 K +QQ +FG + ++ K R + V GEP++LT +E+++ L H GQVFSRE + EK Sbjct: 121 YTKQEQQEEFQFGPILINEKSRKIEVDGEPISLTVKEFDLLYFLCQHTGQVFSREQLLEK 180 Query: 182 VWGYDAEGDASTVVEHVKKIRAKLAAADPSGDYISTVWGIGYKW 225 VWGYD G TV HVK +R KL SG+YI TVWG+GYK+ Sbjct: 181 VWGYDYAGSTRTVDTHVKTMRLKLGE---SGNYIQTVWGVGYKF 221 >ref|NP_655198.1| REC, cheY-homologous receiver domain [Bacillus anthracis A2012] ref|NP_843778.1| DNA-binding response regulator [Bacillus anthracis str. Ames] gb|AAP25264.1| DNA-binding response regulator [Bacillus anthracis str. Ames] Length = 223 Score = 196 bits (497), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 102/224 (45%), Positives = 140/224 (62%), Gaps = 8/224 (3%) Query: 3 RILIIDDEVALVLLLTDELQAKGHEVLAAYDGNEGVR-LADSEPDLVILDIMMPGMNGFE 61 R+L++DDE + L+ L G+E A +G E ++ L D V+LDIMMP M+G Sbjct: 5 RVLVVDDESDMRQLVGMYLDNFGYEWGEAENGKEALKKLETDHYDFVVLDIMMPEMDGLS 64 Query: 62 VCRSIRDRVSCPIIFLSARQSEADRVRGLTLGGDDYVIKPFGLRELLARIEANLRREERS 121 VC+ IR PIIFL+A+ E +RV GL +G DDY++KPF EL+AR+EA LRR Sbjct: 65 VCKEIRKTSDVPIIFLTAKGEEWNRVNGLRMGADDYIVKPFSPGELIARMEAVLRR---- 120 Query: 122 RQKPQQQSRLRFGKLELSLKERLVSVAGEPVALTRREYEITELLALHGGQVFSREHIYEK 181 K +QQ ++FG + ++ K R + GEP++LT +E+++ L H GQVFSRE + EK Sbjct: 121 YTKQEQQEEIQFGPILINEKSRKIEADGEPISLTVKEFDLLYFLCQHTGQVFSREQLLEK 180 Query: 182 VWGYDAEGDASTVVEHVKKIRAKLAAADPSGDYISTVWGIGYKW 225 VWGYD G TV HVK +R KL G+YI TVWG+GYK+ Sbjct: 181 VWGYDYAGSTRTVDTHVKTMRLKLGEG---GNYIQTVWGVGYKF 221 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.138 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 325,663,019 Number of extensions: 12443284 Number of successful extensions: 53055 Number of sequences better than 1.0e-05: 5098 Number of HSP's gapped: 47817 Number of HSP's successfully gapped: 5146 Length of query: 228 Length of database: 757,237,578 Length adjustment: 121 Effective length of query: 107 Effective length of database: 428,710,599 Effective search space: 45872034093 Effective search space used: 45872034093 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 124 (52.4 bits)