BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0562.0008.p (172 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_625483.1| putative tetR-family transcriptional regulator ... 97 1e-19 gb|AAB07865.1| repressor protein 97 2e-19 dbj|BAA21913.1| hemR [Propionibacterium freudenreichii] 96 2e-19 ref|ZP_00069866.1| COG1309: Transcriptional regulator [Oenococcu... 89 3e-17 ref|NP_824796.1| putative TetR-family transcriptional regulator ... 81 1e-14 >ref|NP_625483.1| putative tetR-family transcriptional regulator [Streptomyces coelicolor A3(2)] emb|CAB61605.1| putative tetR-family transcriptional regulator [Streptomyces coelicolor A3(2)] Length = 189 Score = 97.4 bits (241), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 58/146 (39%), Positives = 76/146 (52%), Gaps = 3/146 (2%) Query: 10 LKTRRRGKELEAAILQAVREELKERGYSNLTMDGVAERSGTSKAVLYRRWANRAEIVLAA 69 + RRRG LE A+L A EL ERGY+ TMDGV R+GTS VLYRRWA+R E+ AA Sbjct: 1 MAQRRRGAALEKALLDAAWGELAERGYARFTMDGVVRRAGTSPPVLYRRWAHRDELARAA 60 Query: 70 IRERVPLPLEEVPDYGNLRDDVCGVLRSMNQNNIE---VMMKAFYGLVTEIGAMPLASLI 126 + + + PD G LR D+ ++R + N + +M G E G P L Sbjct: 61 VAHVLEEARVDTPDTGTLRGDLLALMREIGTANAQLVILMYAHLAGYCQETGTSPGELLD 120 Query: 127 FPEGRNNRTMTIVLQRAVDRGEISAE 152 G++ + V RAV RGE E Sbjct: 121 AARGKSADALAEVYDRAVARGEARPE 146 >gb|AAB07865.1| repressor protein Length = 259 Score = 96.7 bits (239), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 64/158 (40%), Positives = 85/158 (53%), Gaps = 13/158 (8%) Query: 11 KTRRRGKELEAAILQAVREELKERGYSNLTMDGVAERSGTSKAVLYRRWANRAEIVLAAI 70 +TRRRG LE AIL A EL GY+ LT + VAER+ T KA LYRRW N+ +VLA + Sbjct: 33 ETRRRGPALEKAILDAGWRELAGAGYAGLTFEAVAERAHTGKAALYRRWPNKESLVLAVL 92 Query: 71 RERVPLPLEEVPDYGNLRDDVCGVLRSMNQNN------IEVMMKAFYGLVTEIGAMPLAS 124 +R VPD G+LR DV VLR N+ I V++ A++ E P Sbjct: 93 SQRYFNDPATVPDTGSLRGDVLAVLRGANRLGDDAPALISVLLGAYF---DETNTTPQEL 149 Query: 125 LIFPEGRNNRTMTIVLQRAVDRGEISAEAXXXLPRGCL 162 G TM ++++RA+ RGE++A LPR L Sbjct: 150 RAHLLGDRVDTMALLVERAIARGEVAAP----LPRRVL 183 >dbj|BAA21913.1| hemR [Propionibacterium freudenreichii] Length = 243 Score = 96.3 bits (238), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 64/158 (40%), Positives = 85/158 (53%), Gaps = 13/158 (8%) Query: 11 KTRRRGKELEAAILQAVREELKERGYSNLTMDGVAERSGTSKAVLYRRWANRAEIVLAAI 70 +TRRRG LE AIL A EL GY+ LT + VAER+ T KA LYRRW N+ +VLA + Sbjct: 17 ETRRRGPALEKAILDAGWRELAGAGYAGLTFEAVAERAHTGKAALYRRWPNKESLVLAVL 76 Query: 71 RERVPLPLEEVPDYGNLRDDVCGVLRSMNQNN------IEVMMKAFYGLVTEIGAMPLAS 124 +R VPD G+LR DV VLR N+ I V++ A++ E P Sbjct: 77 SQRYFNDPATVPDTGSLRGDVLAVLRGANRLGDDAPALISVLLGAYF---DETNTTPQEL 133 Query: 125 LIFPEGRNNRTMTIVLQRAVDRGEISAEAXXXLPRGCL 162 G TM ++++RA+ RGE++A LPR L Sbjct: 134 RAHLLGDRVDTMALLVERAIARGEVAAP----LPRRVL 167 >ref|ZP_00069866.1| COG1309: Transcriptional regulator [Oenococcus oeni MCW] Length = 197 Score = 89.4 bits (220), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 51/144 (35%), Positives = 85/144 (59%), Gaps = 6/144 (4%) Query: 11 KTRRRGKELEAAILQAVREELKERGYSNLTMDGVAERSGTSKAVLYRRWANRAEIVLAAI 70 +TRRRG++LE IL A ++L + GY +LT+ +A +GT+K +YRRW N++ +V++A Sbjct: 6 QTRRRGEKLENTILTAAWDQLNKVGYKDLTITEIASLAGTNKTTIYRRWPNKSLLVVSAF 65 Query: 71 RERVPLPLEEVPDYGNLRDDVCGVLRSMNQNNIEVMMKA-FYGLVTE-IGAMPLASLIFP 128 + VP P +P+ GNLRDD+ + + N +E + F GL+ + + + + Sbjct: 66 SKFVPRPKMHIPNSGNLRDDLVKLFEQL-VNQLEFLTSGKFEGLLLDRLRDTSIDKVFGR 124 Query: 129 EGRNN---RTMTIVLQRAVDRGEI 149 NN + + I+LQRA RGE+ Sbjct: 125 VDENNALQKFIVIILQRAEKRGEL 148 >ref|NP_824796.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680] dbj|BAC71331.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680] Length = 196 Score = 80.9 bits (198), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 58/152 (38%), Positives = 78/152 (51%), Gaps = 8/152 (5%) Query: 6 EQDKLKTRRRGKELEAAILQAVREELKERGYSNLTMDGVAERSGTSKAVLYRRWANRAEI 65 E ++ R E EA + AV + L+E GY LTMD VA R+ +SKA LYR+W +AE+ Sbjct: 3 ETATVRRSRITPEREAELYSAVLDLLREVGYDALTMDAVASRTRSSKATLYRQWGGKAEL 62 Query: 66 VLAAIRERVPLPLEEVPDYGNLRDDVCGVLRSMNQNNIEVMMKAFYGLVTEIGAMP---- 121 V+ A+R + EV D G+LR D ++ N +E GL + A P Sbjct: 63 VVKALRHQKHSHFGEV-DTGSLRGDFHALVTRENNCEMEQNSALMRGLAVAVHANPDLLD 121 Query: 122 -LASLIFPEGRNNRTMTIVLQRAVDRGEISAE 152 LI N M +LQRAVDRGEI A+ Sbjct: 122 AFRDLIIDPETNE--MQRLLQRAVDRGEIRAD 151 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.134 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 221,927,688 Number of extensions: 7892951 Number of successful extensions: 22154 Number of sequences better than 1.0e-05: 47 Number of HSP's gapped: 22162 Number of HSP's successfully gapped: 47 Length of query: 172 Length of database: 757,237,578 Length adjustment: 117 Effective length of query: 55 Effective length of database: 439,570,995 Effective search space: 24176404725 Effective search space used: 24176404725 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 121 (51.2 bits)