BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0560.0016.p (328 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_347012.1| Sensory transduction histidine kinase (HisKA an... 221 3e-56 ref|NP_832298.1| Two-component sensor kinase yxdK [Bacillus cere... 206 4e-52 ref|NP_978924.1| sensor histidine kinase, putative [Bacillus cer... 206 5e-52 ref|NP_783751.1| two-component sensor histidine kinase [Clostrid... 202 1e-50 ref|NP_391351.1| similar to two-component sensor histidine kinas... 190 4e-47 >ref|NP_347012.1| Sensory transduction histidine kinase (HisKA and HATPase damains) [Clostridium acetobutylicum] pir||E96945 sensory transduction histidine kinase (HisKA and HATPase damains) [imported] - Clostridium acetobutylicum gb|AAK78352.1| Sensory transduction histidine kinase (HisKA and HATPase damains) [Clostridium acetobutylicum] Length = 334 Score = 221 bits (562), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 106/317 (33%), Positives = 197/317 (62%), Gaps = 11/317 (3%) Query: 21 YVLNTVILVMASYVFYGVNDILYPLFVSFFILLVYLAVTAVKLNQFTGKLSAAKSSPHIE 80 + L++ I++ YV + D++YP+F+ I ++++ K +F L+ + + Sbjct: 20 FFLSSGIILFYFYVSKNITDVVYPIFMVVSIYIIFIVTEWFKYYRFNANLTRGIEREYYD 79 Query: 81 VDDTNVKDKLIFGAINEIHEQYNGRLHQMNSSIKERNTLFSQWIHNMKVSISIIGLAAEK 140 ++ + ++ AI +IH+ Y ++ +++ + SQWIHNMK +S+I L ++ Sbjct: 80 LESVTPEQRMAQEAILKIHKNYAAKISEIDYKNSDIKYFISQWIHNMKTPVSVIDLIVQR 139 Query: 141 GTE----EAISDIKEENRRLTQNLEECLNLLRLDDFARDYLPEKVNLHKVVNKAVNARKR 196 E + I +I+EEN ++ +++ LN++RLD+F+RDY PE V++ ++V + +N +K Sbjct: 140 EKEKLSGDVIKNIEEENYKIKNGMDQVLNIIRLDEFSRDYEPEIVDIVELVKRTINLKKN 199 Query: 197 EFIYKGVYPQIDIAKHLE---ICTDEKWCGYMLEQVLSNAVKYSDKE--GRVTVRSELAG 251 +FIY +P+++ H++ + TD+KW ++++Q++SN++KYS KE G V + Sbjct: 200 QFIYGNAFPKVEF--HVDKALVLTDKKWSTFIIDQIISNSIKYSKKEEKGYVYFNIVQSN 257 Query: 252 DRVLLSIQDYGVGIDQEDLPRVFDPFFTGKNGRDYRSATGIGLYMVKHIARKLGHRVSID 311 ++ L I+D GVGI + DL R+F+PFFTG+NGR++ ++TGIGLY+ K IA LGH +S++ Sbjct: 258 NKTHLVIKDNGVGIPKYDLKRIFEPFFTGENGRNFENSTGIGLYICKKIADNLGHEISVE 317 Query: 312 SQKGAGTRVTFAFLSKV 328 S+ GT V +++KV Sbjct: 318 SEINKGTIVKITYMAKV 334 >ref|NP_832298.1| Two-component sensor kinase yxdK [Bacillus cereus ATCC 14579] gb|AAP09499.1| Two-component sensor kinase yxdK [Bacillus cereus ATCC 14579] Length = 327 Score = 206 bits (525), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 117/319 (36%), Positives = 182/319 (57%), Gaps = 14/319 (4%) Query: 18 LLVYVLNTVILVMASYVFYGVNDI---LYPLFVSFFILLVYLAVTAVKLNQFTGKLSAAK 74 L+ + + ++ + Y F G N I LY +F+ F + YL F +L+ Sbjct: 12 LICFTIIQLLAIFLVYWFDGHNHITTALYAMFLGVFFMGSYLVFRYFTHRSFYERLA--- 68 Query: 75 SSPHIEVDDTNVKDKL--IFGAINEIHE-QYNGRLHQMNSSIKERN---TLFSQWIHNMK 128 +P +D++ K + A+ E+ E QY +Q+ ++ N T +QWIH MK Sbjct: 69 -NPMQSLDESVQKSDFAAVSAALQELLEVQYRHYQNQLQMQERKNNDHLTFMNQWIHQMK 127 Query: 129 VSISIIGLAAEKGTEEAISDIKEENRRLTQNLEECLNLLRLDDFARDYLPEKVNLHKVVN 188 +S+I L + + I EE RL + LE L + RL+ F +D+ E+V LHK+VN Sbjct: 128 TPLSVIELITQDEVDSRFESINEETDRLKKGLEMALYVARLEAFTQDFYVERVQLHKIVN 187 Query: 189 KAVNARKREFIYKGVYPQIDIAKHLEICTDEKWCGYMLEQVLSNAVKYSD-KEGRVTVRS 247 +V+ KR FI VYP+++I K + + +D KW +++ Q+LSNA+KYS ++ V++ Sbjct: 188 DSVHEHKRFFIRNFVYPELEIDKDITVESDAKWLQFLIGQILSNAIKYSSGSREKIKVKA 247 Query: 248 ELAGDRVLLSIQDYGVGIDQEDLPRVFDPFFTGKNGRDYRSATGIGLYMVKHIARKLGHR 307 G+ V+L I D GVGI ++DLPRVF PFFTG+NGRD++ +TG+GLY+V I ++LGH Sbjct: 248 CKEGNNVILEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMGLYLVYEITKQLGHS 307 Query: 308 VSIDSQKGAGTRVTFAFLS 326 V I S+ G GT V F + Sbjct: 308 VEIYSEVGKGTVVRIIFFN 326 >ref|NP_978924.1| sensor histidine kinase, putative [Bacillus cereus ATCC 10987] gb|AAS41532.1| sensor histidine kinase, putative [Bacillus cereus ATCC 10987] Length = 334 Score = 206 bits (524), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 122/319 (38%), Positives = 181/319 (56%), Gaps = 18/319 (5%) Query: 18 LLVYVLNTVILVMASYVFYGVNDI---LYPLFVSFFILLVYLAVTAVKLNQFTGKLSAAK 74 L+ + ++ + Y F G N I LY +F+ F ++ YL F +L+ Sbjct: 19 LICFTAIQLLAIFLVYWFDGHNRIATALYAMFLGAFFMVGYLLFRYYTHRSFYERLA--- 75 Query: 75 SSPHIEVDDTNVKDKL--IFGAINEIHE-QYNGRLHQMNSSIKERN-----TLFSQWIHN 126 +P +D++ K I A+ ++ E QY R +Q I+ER T +QWIH Sbjct: 76 -NPMQSLDESVQKSDFAAISAALQDLLEVQY--RHYQNQLQIQERKNNDHLTFMNQWIHQ 132 Query: 127 MKVSISIIGLAAEKGTEEAISDIKEENRRLTQNLEECLNLLRLDDFARDYLPEKVNLHKV 186 MK +S+I L + E I EE RL + LE L + RL+ F +D+ E+V LHK+ Sbjct: 133 MKTPLSVIELITQDEVEPRFESINEETDRLKKGLEMALYVARLEAFTQDFYVERVQLHKI 192 Query: 187 VNKAVNARKREFIYKGVYPQIDIAKHLEICTDEKWCGYMLEQVLSNAVKYSD-KEGRVTV 245 VN +V+ KR FI VYP++ I K + + +D KW +++ Q+LSNA+KYS ++ V Sbjct: 193 VNDSVHEHKRFFIRNFVYPELKIDKDITVESDAKWLQFLIGQILSNAIKYSSGSREKIRV 252 Query: 246 RSELAGDRVLLSIQDYGVGIDQEDLPRVFDPFFTGKNGRDYRSATGIGLYMVKHIARKLG 305 R+ G+ V+L I D GVGI ++DLPRVF PFFTG+NGRD++ +TG+GLY+V I ++LG Sbjct: 253 RACKEGNNVILEIADNGVGIXKQDLPRVFKPFFTGENGRDFKESTGMGLYLVYEITKQLG 312 Query: 306 HRVSIDSQKGAGTRVTFAF 324 H V I S+ G GT V F Sbjct: 313 HSVEIHSEVGKGTVVRIKF 331 >ref|NP_783751.1| two-component sensor histidine kinase [Clostridium tetani] gb|AAO37418.1| two-component sensor histidine kinase [Clostridium tetani] Length = 314 Score = 202 bits (513), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 110/306 (35%), Positives = 175/306 (57%), Gaps = 4/306 (1%) Query: 17 MLLVYVLNTVILVMASYVFYGVNDIL-YPLFVSFFILLVYLAVTAVKLNQFTGKLSAAKS 75 M+++Y++N ++L G + + Y +F+S F L+ +L + Q KLS Sbjct: 1 MIILYIINFIVLAFFYNKLGGFKENMSYFIFLSLFFLMCFLVYKYILNKQIYKKLSEKPK 60 Query: 76 S--PHIEVDDTNVKDKLIFGAINEIHEQYNGRLHQMNSSIKERNTLFSQWIHNMKVSISI 133 S + +D + ++ F I E + YN ++ M +S KE + + W+H MK +S+ Sbjct: 61 SMDDMLTIDPHSPLEEAFFKTIQEYMKLYNKDINFMKNSQKEYKIMLNNWVHQMKTPVSV 120 Query: 134 IGLAAEKGTE-EAISDIKEENRRLTQNLEECLNLLRLDDFARDYLPEKVNLHKVVNKAVN 192 I L A+ + E + ENRR+ NL + L LR+DDFA D EKVNL V + VN Sbjct: 121 INLLAQNNYDNEDFQKVALENRRIDYNLSQILTFLRIDDFANDMKIEKVNLKIVALEVVN 180 Query: 193 ARKREFIYKGVYPQIDIAKHLEICTDEKWCGYMLEQVLSNAVKYSDKEGRVTVRSELAGD 252 K FI + V+P++ I+++L I TD+KW Y + Q+++NA+KYS K G V + + D Sbjct: 181 ELKEFFITQSVFPKLSISQNLSINTDKKWIKYAIYQIVNNAIKYSKKNGTVYINGFVEED 240 Query: 253 RVLLSIQDYGVGIDQEDLPRVFDPFFTGKNGRDYRSATGIGLYMVKHIARKLGHRVSIDS 312 V+L I + G+GI + D+ R+FD FFTG NGR + +TG+GLY+VK + L H++S+ S Sbjct: 241 MVVLEIINRGIGIKKSDINRIFDVFFTGDNGRTFGESTGVGLYIVKKVLDILDHKISVKS 300 Query: 313 QKGAGT 318 + G T Sbjct: 301 KPGEET 306 >ref|NP_391351.1| similar to two-component sensor histidine kinase [YvcP] [Bacillus subtilis] pir||E70032 two-component sensor histidine kinase homolog yvcQ - Bacillus subtilis emb|CAB08063.1| hypothetical protein [Bacillus subtilis] emb|CAB15476.1| yvcQ [Bacillus subtilis subsp. subtilis str. 168] Length = 356 Score = 190 bits (483), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 93/243 (38%), Positives = 151/243 (62%), Gaps = 12/243 (4%) Query: 95 INEIHEQYNGRLHQMNSSIKERNTLFSQWIHNMKVSISIIGLAAEKGTEEAIS------- 147 IN + +QY RL Q + K+ T +QW+H+MK +S+I L ++G S Sbjct: 106 INALGQQYESRLSQYINQQKQHYTFTNQWVHHMKTPVSVISLMIQEGKNGTSSSFPTFLE 165 Query: 148 DIKEENRRLTQNLEECLNLLRLDDFARDYLPEKVNLHKVVNKAVNARKREFIYKGVYPQI 207 ++++EN R L+ L RL++FA D P+ +L ++V +N KR+FI + ++P + Sbjct: 166 ELEDENERFRHGLDMMLQTARLEEFAFDVKPQTFDLAEMVRSLINQEKRQFIKRRLFPTL 225 Query: 208 DIAKH-LEICTDEKWCGYMLEQVLSNAVKYSDKEG---RVTVRSELAGDRVLLSIQDYGV 263 + + ++I +D+KW +++EQ+L NA+KYS K+G +T+R E G LS+ D G+ Sbjct: 226 HVPPNAVQISSDQKWLSFVVEQILFNALKYS-KQGVGDPITIRIETQGHETRLSVADEGI 284 Query: 264 GIDQEDLPRVFDPFFTGKNGRDYRSATGIGLYMVKHIARKLGHRVSIDSQKGAGTRVTFA 323 GI +DLPR+FD FFTG+NGR + ATG+GLY+ K + +LGH++ +S++GAGT +T Sbjct: 285 GIPPQDLPRIFDAFFTGENGRTMKEATGMGLYLAKQVCSRLGHKLYAESKEGAGTVMTIV 344 Query: 324 FLS 326 F S Sbjct: 345 FSS 347 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.322 0.138 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 451,425,474 Number of extensions: 18416256 Number of successful extensions: 66086 Number of sequences better than 1.0e-05: 2057 Number of HSP's gapped: 66723 Number of HSP's successfully gapped: 2062 Length of query: 328 Length of database: 757,237,578 Length adjustment: 126 Effective length of query: 202 Effective length of database: 415,135,104 Effective search space: 83857291008 Effective search space used: 83857291008 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 126 (53.1 bits)