BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0557.0039.p (217 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value emb|CAD41944.1| BtrW protein [Bacillus circulans] 283 3e-75 ref|NP_241853.1| transcriptional regulator (TetR/AcrR family) [B... 77 3e-13 ref|NP_625398.1| putative tetR-family transcriptional regulatory... 77 3e-13 ref|NP_793472.1| transcriptional regulator, TetR family [Pseudom... 71 2e-11 ref|ZP_00124475.1| COG1309: Transcriptional regulator [Pseudomon... 70 4e-11 >emb|CAD41944.1| BtrW protein [Bacillus circulans] Length = 217 Score = 283 bits (723), Expect = 3e-75, Method: Compositional matrix adjust. Identities = 135/216 (62%), Positives = 161/216 (74%) Query: 1 MSPRTKKQNELIREQRKQEILQAAIHVYVTKGYAATTLGDIAVQAGLAHGLVYYYFKNKK 60 MSPRTK+QNE IR QRK+E+LQAA+ VYV KGYAA +GDIA +AGLAHGLVYYYFKNKK Sbjct: 1 MSPRTKEQNEAIRNQRKREVLQAAVQVYVEKGYAAAEMGDIADRAGLAHGLVYYYFKNKK 60 Query: 61 QLFRELYEYMMEQSLRYTTAYFEQDLPVMAQFKNYATIVCERVIKDPQTQRFYMRISLDL 120 LFRELYE MME S +T +YFEQ V F++YA +VCERV +P RFYMRISLD+ Sbjct: 61 ALFRELYETMMEGSKCFTKSYFEQKGSVSDLFESYARVVCERVRVNPAIPRFYMRISLDV 120 Query: 121 HHLYEPGELSPFDWMKSFVKPMAQAIDRGIRQGVIRQGDANLMAMQFWGAISQGMNYLDQ 180 HHLY P E SPF W+KSF++ M QAI++GI +G IR G+ +LMA QFWGA+SQGMNYLDQ Sbjct: 121 HHLYTPEEFSPFSWVKSFLQEMTQAIEKGIGEGTIRPGNPDLMARQFWGAVSQGMNYLDQ 180 Query: 181 LLQELAAQGLTETEANGAVNDKFNQVAESAISFFKL 216 QE A G+ ETE QV ES++S +L Sbjct: 181 AQQEWMANGMPETEKKEQWEKALTQVVESSVSILRL 216 >ref|NP_241853.1| transcriptional regulator (TetR/AcrR family) [Bacillus halodurans] pir||C83773 transcription regulator (TetR/AcrR family) BH0987 [imported] - Bacillus halodurans (strain C-125) dbj|BAB04706.1| transcriptional regulator (TetR/AcrR family) [Bacillus halodurans] Length = 203 Score = 77.0 bits (188), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 51/184 (27%), Positives = 97/184 (52%), Gaps = 7/184 (3%) Query: 4 RTKKQNELIREQRKQEILQAAIHVYVTKGYAATTLGDIAVQAGLAHGLVYYYFKNKKQLF 63 RTK+QNE + +++I +AA+ ++ KG+A TT+ DI+ +A ++ GLVY +F +K++LF Sbjct: 3 RTKEQNERMSMATREKIYKAALSLFAHKGFALTTIKDISREAHISTGLVYRHFHSKEELF 62 Query: 64 RELYEYMMEQSLRYTTAYFEQDLPVMAQFKNYATIVCERVIKDPQTQRFYMRISLDLHH- 122 L E + + + T + E D + T + + + +++ ++ L Sbjct: 63 GRLIEKAIGE-MTSVTKFLETDTSPKELVSEFVTKMIAGIQSSEEVSHYFLLVARSLLED 121 Query: 123 --LYEPGELSPFDWMKSFVKPMAQAIDRGIRQGVIRQGDANLMAMQFWGAISQGMNYLDQ 180 L + G+L D + + MA+ I RG RQG ++GD+ +++ + I QGM + Sbjct: 122 EVLPKIGDLKKTDL--ALFQQMAELIARGQRQGEFKEGDSYKLSLLLFSII-QGMANMKM 178 Query: 181 LLQE 184 + E Sbjct: 179 FMGE 182 >ref|NP_625398.1| putative tetR-family transcriptional regulatory protein [Streptomyces coelicolor A3(2)] emb|CAB95991.1| putative tetR-family transcriptional regulatory protein [Streptomyces coelicolor A3(2)] Length = 233 Score = 76.6 bits (187), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 36/75 (48%), Positives = 50/75 (66%) Query: 1 MSPRTKKQNELIREQRKQEILQAAIHVYVTKGYAATTLGDIAVQAGLAHGLVYYYFKNKK 60 MSPR+ NE +R + K+ +LQAA+ + +GY ATTLGDIA +AG A GLV YYF K+ Sbjct: 1 MSPRSASVNEELRRRSKERLLQAAVELVGERGYEATTLGDIADRAGSARGLVSYYFPGKR 60 Query: 61 QLFRELYEYMMEQSL 75 QL + +M ++L Sbjct: 61 QLVQSAVHRLMHRTL 75 >ref|NP_793472.1| transcriptional regulator, TetR family [Pseudomonas syringae pv. tomato str. DC3000] gb|AAO57167.1| transcriptional regulator, TetR family [Pseudomonas syringae pv. tomato str. DC3000] Length = 202 Score = 70.9 bits (172), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 34/76 (44%), Positives = 51/76 (67%) Query: 12 IREQRKQEILQAAIHVYVTKGYAATTLGDIAVQAGLAHGLVYYYFKNKKQLFRELYEYMM 71 IRE+ K+ IL+AA + KG+AA+ DIA +AG+ VYYYFK+K+ L+RE+ E ++ Sbjct: 4 IRERNKELILRAASEEFADKGFAASKTSDIAAKAGVPKPNVYYYFKSKENLYREVLESII 63 Query: 72 EQSLRYTTAYFEQDLP 87 E LR +T + Q +P Sbjct: 64 EPILRASTPFNPQGVP 79 >ref|ZP_00124475.1| COG1309: Transcriptional regulator [Pseudomonas syringae pv. syringae B728a] Length = 202 Score = 69.7 bits (169), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 33/76 (43%), Positives = 51/76 (67%) Query: 12 IREQRKQEILQAAIHVYVTKGYAATTLGDIAVQAGLAHGLVYYYFKNKKQLFRELYEYMM 71 IRE+ K+ IL+AA + KG+AA+ DIA +AG+ VYYYFK+K+ L+RE+ E ++ Sbjct: 4 IRERNKELILRAASEEFADKGFAASKTSDIAAKAGVPKPNVYYYFKSKENLYREVLESII 63 Query: 72 EQSLRYTTAYFEQDLP 87 E LR +T + + +P Sbjct: 64 EPILRASTPFNPEGVP 79 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.322 0.135 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 295,568,374 Number of extensions: 11056398 Number of successful extensions: 29820 Number of sequences better than 1.0e-05: 103 Number of HSP's gapped: 29843 Number of HSP's successfully gapped: 103 Length of query: 217 Length of database: 757,237,578 Length adjustment: 121 Effective length of query: 96 Effective length of database: 428,710,599 Effective search space: 41156217504 Effective search space used: 41156217504 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 123 (52.0 bits)