BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0557.0013.p (350 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value emb|CAD41946.1| BtrU protein [Bacillus circulans] 379 e-104 ref|ZP_00100834.1| hypothetical protein [Desulfitobacterium hafn... 185 1e-45 ref|ZP_00117038.1| hypothetical protein [Cytophaga hutchinsonii] 161 2e-38 ref|NP_720519.1| conserved hypothetical protein [Streptococcus m... 150 6e-35 gb|AAF23890.1| Suppressor of Fused [Homo sapiens] >gi|37182223|g... 134 3e-30 >emb|CAD41946.1| BtrU protein [Bacillus circulans] Length = 390 Score = 379 bits (972), Expect = e-104, Method: Compositional matrix adjust. Identities = 194/350 (55%), Positives = 233/350 (66%), Gaps = 4/350 (1%) Query: 5 ELNADGWAAIDEALEQLYGEQEQKHYGTVIPYMLGGPDPLNGISVYEVREPLPHWHFVTY 64 E N GW AID+ +LYG+QE KHYGT+I Y LGGPDPL+GIS Y+ EP PHWHFVT+ Sbjct: 41 EPNTAGWDAIDKEFVKLYGDQEPKHYGTLISYALGGPDPLDGISAYKTDEPAPHWHFVTF 100 Query: 65 GFSELYEKESDDPEHSGYGFELTFRLFKPATEDEPPAWALNLLQNLGRYVFNSGNVFRSG 124 GFSELY+KESD PE SGYGFELTFRL + A E+EPPAWA+NLLQN+GRYVFNSGN+FRSG Sbjct: 101 GFSELYDKESDHPEESGYGFELTFRLDRGAEEEEPPAWAINLLQNMGRYVFNSGNIFRSG 160 Query: 125 DYMDANGPIXXXXXXXXXXXXFIADPLLRAIDTPNGRLEFIQLVGITNDELLAMQVWNTL 184 DYMDANGPI FI DP L AIDTPNGR+EFIQ+VGIT DEL AMQ WNTL Sbjct: 161 DYMDANGPICLGSDTRLTALAFIRDPELPAIDTPNGRVEFIQMVGITRDELEAMQTWNTL 220 Query: 185 GVLAEMTEHLPLYMTDLQRDSLLKLPAIAEAVRLGSENEGSNTGALYVDQLAWENPAEGS 244 G+L+ ++P Y+T+L RDSLLK+ A++EA G +GSNTG L+VDQLAWE +G Sbjct: 221 GMLSACLPYMPHYITNLSRDSLLKVEAVSEAAEKGMREDGSNTGFLFVDQLAWEPGKKGW 280 Query: 245 VH----TLQLGAKQAEIVXXXXXXXXXXXXXXXXAGPEISVSFETGDTPGFEIREELVIL 300 + L LGAKQA I+ GPE+ F+ G+ P + V + Sbjct: 281 LSKAPAALTLGAKQAGIIGKLLQGRILKGKDFTLVGPEVRAIFKAGEKPECAAGDGEVRI 340 Query: 301 KLDEAAGAALSEIFRPSAGLYPLPGWPELAIRIVPTHITDSEGTIVKTIG 350 LDE A LS P + +P IRIV T+I DSEG +V+ IG Sbjct: 341 MLDEQAAGELSRGLIPKESVLEIPSLQGTVIRIVKTNIKDSEGNVVEVIG 390 >ref|ZP_00100834.1| hypothetical protein [Desulfitobacterium hafniense] Length = 211 Score = 185 bits (470), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 93/184 (50%), Positives = 116/184 (63%), Gaps = 4/184 (2%) Query: 3 EEELNADGWAAIDEALEQLYGEQEQKHYGTVIPYMLGGPDPLNGISVYEVREPLPHWHFV 62 E A GW AI+ AL ++Y Q H + P G PL GIS Y+ PLPHWHFV Sbjct: 31 RSEAGAPGWDAINHALNRVYPRQSPWH-SSAPP---GSAAPLPGISAYKRITPLPHWHFV 86 Query: 63 TYGFSELYEKESDDPEHSGYGFELTFRLFKPATEDEPPAWALNLLQNLGRYVFNSGNVFR 122 TYGFSEL++K +DD SGYGFELTFRL P +EPP WALN LQNL RYVF+SG+ F Sbjct: 87 TYGFSELFDKRNDDAATSGYGFELTFRLANPDDAEEPPRWALNFLQNLARYVFDSGHGFH 146 Query: 123 SGDYMDANGPIXXXXXXXXXXXXFIADPLLRAIDTPNGRLEFIQLVGITNDELLAMQVWN 182 +G Y+ A GPI F+ DP L +D+ NGRLEF+Q+VG+TN+E ++ W+ Sbjct: 147 AGHYLSAGGPIAADSDSQIRALAFVQDPELAPVDSDNGRLEFLQIVGLTNEEEFELKRWS 206 Query: 183 TLGV 186 TL Sbjct: 207 TLKC 210 >ref|ZP_00117038.1| hypothetical protein [Cytophaga hutchinsonii] Length = 210 Score = 161 bits (408), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 84/200 (42%), Positives = 121/200 (60%), Gaps = 4/200 (2%) Query: 5 ELNADGWAAIDEALEQLYGEQEQKHYGTVIPYMLGGPDPLNGISVYEVREPLPHWHFVTY 64 E + GW AID+ ++ +Y QE +HY +V+ YM+GGPDPL+G S+Y+ + H H ++Y Sbjct: 12 EDDTPGWQAIDKVIDTVYAGQEPRHYASVMKYMIGGPDPLDGTSIYDSHQQTFHRHVISY 71 Query: 65 GFSEL-YEKESDDPEHSGYGFELTFRLFKPATEDEPPAWALNLLQNLGRYVFNSGNVFRS 123 G SEL Y E D E S +GFE T R+ ED+ P W + L+ NL RYVF++GN F + Sbjct: 72 GMSELYYAPEKADKEFSNWGFEFTMRIKSTEVEDD-PKWVIGLMNNLARYVFDTGNWFEA 130 Query: 124 GDYMDANGPIXXXXXXXXXXXXFIADPLLRAIDTPNGRLEFIQLVGITNDELLAMQVWNT 183 Y+ ANGPI FI DP L I TP+G++ F+QL+GIT EL ++ Sbjct: 131 YHYIPANGPIKLESKTDKVGVLFITDPELGTISTPHGQVTFLQLIGITEAELERLKKSPE 190 Query: 184 LG--VLAEMTEHLPLYMTDL 201 G ++ EM + PL++T+L Sbjct: 191 EGELLIEEMRVNNPLFITEL 210 >ref|NP_720519.1| conserved hypothetical protein [Streptococcus mutans UA159] gb|AAN57825.1| conserved hypothetical protein [Streptococcus mutans UA159] Length = 235 Score = 150 bits (378), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 82/205 (40%), Positives = 121/205 (59%), Gaps = 7/205 (3%) Query: 7 NADGWAAIDEALEQLYGEQEQK-HYGTVIPYMLGGPDPLNGISVYEVREPLPHWHFVTYG 65 +A GW AID ++LY +Q HYGT++ YM GGPDPL+GISVY+ + WHFV+YG Sbjct: 34 SAPGWEAIDAEFDRLYPDQPNPLHYGTIVKYMFGGPDPLDGISVYDAGD---FWHFVSYG 90 Query: 66 FSELYEKESDDPEHSGYGFELTFRLFKPATEDEPPAWALNLLQNLGRYVFNSGNVFRSGD 125 SELY KES D E+SGYG ELTF+L K ++E LLQ + RY+F +G V + Sbjct: 91 LSELYTKESTDSEYSGYGIELTFKLKKSTNDEEEIKNGCGLLQYVARYIFKTGKVVLPEE 150 Query: 126 YMDANGPIXXXXXXXXXXXXF--IADPLLRAIDTPNGRLEFIQLVGITNDELLAMQVWNT 183 Y+ + F ++D L + +DTP+G++EF+ L+G T+ EL ++ T Sbjct: 151 YIYMKQTVGIDIQQKSKLTGFLTVSDNLAKPLDTPHGKVEFVTLIGATDAELRSVYESET 210 Query: 184 LGV-LAEMTEHLPLYMTDLQRDSLL 207 + + ++ + L +TD R SL+ Sbjct: 211 SKLEVRKLLQELGNQITDYNRQSLV 235 >gb|AAF23890.1| Suppressor of Fused [Homo sapiens] gb|AAQ88914.1| SUFU [Homo sapiens] Length = 433 Score = 134 bits (338), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 87/250 (34%), Positives = 135/250 (54%), Gaps = 25/250 (10%) Query: 10 GWAAIDEALEQLYGEQEQK-HYGTVIPYMLGGPDPLNGISVYE-VREP---LP-HWHFVT 63 G AI +LY +Q ++ Y LGGPDPL+ +S+Y V P +P HWH+++ Sbjct: 33 GLHAIYGECRRLYPDQPNPLQVTAIVKYWLGGPDPLDYVSMYRNVGSPSANIPEHWHYIS 92 Query: 64 YGFSELYEKE-------SDDPEHSGYGFELTFRLFKPATEDEPPAWALNLLQNLGRYVFN 116 +G S+LY +D P SG+GFELTFRL + E PP W L+Q L RYVF Sbjct: 93 FGLSDLYGDNRVHEFTGTDGP--SGFGFELTFRLKRETGESAPPTWPAELMQGLARYVFQ 150 Query: 117 SGNVFRSGDYMDANGPIXXXXXXXXXXXXFIADPLLRAIDTPNGRLEFIQLVGITNDELL 176 S N F SGD++ + P+ DP ++ + TP G + F+Q+VG+ +EL Sbjct: 151 SENTFCSGDHVSWHSPL-DNSESRIQHMLLTEDPQMQPVQTPFGVVTFLQIVGVCTEELH 209 Query: 177 AMQVWNTLGVLAEMTEHLPL-----YMTDLQR-DSLLKL-PAIAEAVRLGSENEGSNTGA 229 + Q WN G+L E+ +P+ +TD++R +++ ++ P + E V G E +GSN Sbjct: 210 SAQQWNGQGIL-ELLRTVPIAGGPWLITDMRRGETIFEIDPHLQERVDKGIETDGSNLSG 268 Query: 230 LYVDQLAWEN 239 + + AW++ Sbjct: 269 VSA-KCAWDD 277 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.316 0.137 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 513,259,531 Number of extensions: 20707499 Number of successful extensions: 29146 Number of sequences better than 1.0e-05: 22 Number of HSP's gapped: 29083 Number of HSP's successfully gapped: 22 Length of query: 350 Length of database: 757,237,578 Length adjustment: 126 Effective length of query: 224 Effective length of database: 415,135,104 Effective search space: 92990263296 Effective search space used: 92990263296 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 126 (53.1 bits)