BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0548.0014.p (85 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00098374.1| COG2207: AraC-type DNA-binding domain-contain... 70 1e-11 ref|ZP_00035519.1| COG4753: Response regulator containing CheY-l... 65 4e-10 ref|NP_269623.1| putative two-component response regulator [Stre... 65 6e-10 ref|NP_801922.1| putative two-component response regulator [Stre... 64 1e-09 ref|NP_665006.1| putative two-component response regulator [Stre... 64 1e-09 >ref|ZP_00098374.1| COG2207: AraC-type DNA-binding domain-containing proteins [Desulfitobacterium hafniense] Length = 428 Score = 70.5 bits (171), Expect = 1e-11, Method: Composition-based stats. Identities = 33/84 (39%), Positives = 52/84 (61%) Query: 2 LRDAANHFSFSPNHLGQIFYEETGVYFSDYVGLRRLERVKVLLSDPKLKVYEAANRVGYK 61 + DAA H SP+HL ++F ++ F+DY+ R+E+ LL P+ V + A VG++ Sbjct: 344 IADAAQHLFISPSHLSRLFRQQLDCTFNDYLTRVRVEKAVELLKKPEFSVKDVALAVGFQ 403 Query: 62 NLSHFSKQFKEFYGVSPGDYRRHL 85 N SHF+K F+++ GV+P YR L Sbjct: 404 NQSHFAKVFRKYIGVTPLVYRNSL 427 >ref|ZP_00035519.1| COG4753: Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Enterococcus faecium] Length = 242 Score = 65.5 bits (158), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 34/84 (40%), Positives = 51/84 (60%) Query: 2 LRDAANHFSFSPNHLGQIFYEETGVYFSDYVGLRRLERVKVLLSDPKLKVYEAANRVGYK 61 L+D A F + P +LG+ F +ETG F DY+ R++R LL D L + E + +VG Sbjct: 158 LKDVATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGID 217 Query: 62 NLSHFSKQFKEFYGVSPGDYRRHL 85 ++S+FS FK+ G SP +YR+ L Sbjct: 218 HVSYFSVLFKKTTGHSPSNYRKKL 241 >ref|NP_269623.1| putative two-component response regulator [Streptococcus pyogenes] gb|AAK34344.1| putative two-component response regulator [Streptococcus pyogenes M1 GAS] Length = 246 Score = 64.7 bits (156), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 32/82 (39%), Positives = 55/82 (67%) Query: 2 LRDAANHFSFSPNHLGQIFYEETGVYFSDYVGLRRLERVKVLLSDPKLKVYEAANRVGYK 61 L+ A FSPN+L + +E G+ F DY+ RL++ K+LL LK+YE A +VG++ Sbjct: 161 LKSLAQQLGFSPNYLSVLIKKELGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVGFE 220 Query: 62 NLSHFSKQFKEFYGVSPGDYRR 83 ++++FS++FK+ GV+P Y++ Sbjct: 221 DMNYFSQRFKQLVGVTPSQYKK 242 >ref|NP_801922.1| putative two-component response regulator [Streptococcus pyogenes SSI-1] dbj|BAC63755.1| putative two-component response regulator [Streptococcus pyogenes SSI-1] Length = 243 Score = 63.5 bits (153), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 31/82 (37%), Positives = 55/82 (67%) Query: 2 LRDAANHFSFSPNHLGQIFYEETGVYFSDYVGLRRLERVKVLLSDPKLKVYEAANRVGYK 61 L+ A FSPN+L + ++ G+ F DY+ RL++ K+LL LK+YE A +VG++ Sbjct: 158 LKSLAQQLGFSPNYLSVLIKKDLGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVGFE 217 Query: 62 NLSHFSKQFKEFYGVSPGDYRR 83 ++++FS++FK+ GV+P Y++ Sbjct: 218 DMNYFSQRFKQLVGVTPSQYKK 239 >ref|NP_665006.1| putative two-component response regulator [Streptococcus pyogenes MGAS315] gb|AAM79809.1| putative two-component response regulator [Streptococcus pyogenes MGAS315] Length = 246 Score = 63.5 bits (153), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 31/82 (37%), Positives = 55/82 (67%) Query: 2 LRDAANHFSFSPNHLGQIFYEETGVYFSDYVGLRRLERVKVLLSDPKLKVYEAANRVGYK 61 L+ A FSPN+L + ++ G+ F DY+ RL++ K+LL LK+YE A +VG++ Sbjct: 161 LKSLAQQLGFSPNYLSVLIKKDLGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVGFE 220 Query: 62 NLSHFSKQFKEFYGVSPGDYRR 83 ++++FS++FK+ GV+P Y++ Sbjct: 221 DMNYFSQRFKQLVGVTPSQYKK 242 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.323 0.141 0.420 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 132,835,314 Number of extensions: 4396709 Number of successful extensions: 14398 Number of sequences better than 1.0e-05: 145 Number of HSP's gapped: 14555 Number of HSP's successfully gapped: 145 Length of query: 85 Length of database: 757,237,578 Length adjustment: 54 Effective length of query: 31 Effective length of database: 610,622,232 Effective search space: 18929289192 Effective search space used: 18929289192 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 120 (50.8 bits)