BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0544.0029.p (189 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_266393.1| transcription regulator [Lactococcus lactis sub... 104 1e-21 gb|AAL17923.1| putative transcription regulator [Mycobacterium s... 91 2e-17 ref|NP_624661.1| putative transcriptional regulator [Streptomyce... 85 1e-15 ref|NP_624835.1| putative TetR family transcriptional regulator ... 78 8e-14 gb|AAK19882.1| putative transcriptional repressor ButR [Streptom... 75 7e-13 >ref|NP_266393.1| transcription regulator [Lactococcus lactis subsp. lactis] pir||E86654 transcription regulator [imported] - Lactococcus lactis subsp. lactis (strain IL1403) gb|AAK04335.1| transcriptional regulator [Lactococcus lactis subsp. lactis] Length = 181 Score = 104 bits (259), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 59/164 (35%), Positives = 95/164 (57%), Gaps = 5/164 (3%) Query: 2 IKLKSKEKLQAAATKLFMEKGYENTTVQEIASLAGVTERTFFRQFKDKSDVLFDTNNELG 61 +K S+EKL AA +L +GYENTTV +IA+ AG+TERTFFR+FK+K+D+ F + Sbjct: 1 MKKTSQEKLYEAALELITAQGYENTTVLQIATKAGLTERTFFRKFKNKADIFFAGGEQYS 60 Query: 62 QRVAAFITDNVDVEKKPLKLAVEGFVSTSXXXXXXXGSRERVLARNQIIQSNPDLQEREL 121 Q + + ++ PL + +E + + RER + R +II S+PDL+EREL Sbjct: 61 QMLLTKMKES--KANNPLAIVLESYFYAADFFDE---HRERTVKRQKIIASHPDLEEREL 115 Query: 122 LKGQRLIASVTNSLAATYDSDLSELAARFAVGIFHMAFMKWIKS 165 LK ++ + L Y + LA R A ++ +A+ +W+++ Sbjct: 116 LKQSKIEELLVEYLLTAYGERSARLAVRLARAVYSVAWEEWLEN 159 >gb|AAL17923.1| putative transcription regulator [Mycobacterium smegmatis] Length = 194 Score = 90.5 bits (223), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 62/171 (36%), Positives = 96/171 (56%), Gaps = 12/171 (7%) Query: 6 SKEKLQAAATKLFMEKGYENTTVQEIASLAGVTERTFFRQFKDKSDVLFDTNNELGQRVA 65 S+++L+ AAT+LF E+G++NTT EIA A VT RTFFR F DK V+F L + Sbjct: 8 SEDRLKQAATELFEERGFQNTTAVEIAKRARVTTRTFFRYFADKQAVVFADAERLRAALI 67 Query: 66 AFITDNVDVEKKPLK---LAVEGFVSTSXXXXXXXGSRERVLARNQIIQSNPDLQERELL 122 + + D +PL+ + GF S GSRE R+++I SNP+L ER+L+ Sbjct: 68 QQLGNTADA-GQPLRSVTAVLAGFDWES------LGSRESQRRRDRMIASNPELLERDLM 120 Query: 123 KGQRLIASVTNSLAAT-YDSDLSELAARFAVGIFHMAFMKWIKSAEKGLAE 172 K + + + L + +ELAAR + +F A+ +W+ +A++G AE Sbjct: 121 KQHEMAEAFSGVLRERGVEPYAAELAARVGIDVFRTAYRRWL-AADEGDAE 170 >ref|NP_624661.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)] emb|CAB56142.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)] Length = 188 Score = 84.7 bits (208), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 54/161 (33%), Positives = 84/161 (52%), Gaps = 5/161 (3%) Query: 6 SKEKLQAAATKLFMEKGYENTTVQEIASLAGVTERTFFRQFKDKSDVLFDTNNELGQRVA 65 ++++L+ AA +L+ E GY+N TV +IA AG+T R++FR F DK +VLF + L VA Sbjct: 8 AEQRLKRAALELYSEHGYDNVTVTDIAERAGLTRRSYFRYFPDKREVLFGGSELLPPAVA 67 Query: 66 AFITDNVDVEKKPLKLAVEGFVSTSXXXXXXXGSRERVLARNQIIQSNPDLQERELLKGQ 125 + D PL ++ S E R +I ++P+LQERE K Sbjct: 68 RAVL-AADPGAAPLTAVLDAM---SQVGAQLVAQVEGAAQRRAVIDASPELQERERTKSA 123 Query: 126 RLIASVTNSLA-ATYDSDLSELAARFAVGIFHMAFMKWIKS 165 + +V ++L D+D +EL A+ A F AF +WI + Sbjct: 124 AISRAVQDALVRRQVDADTAELVAQLATVAFGSAFRRWIDA 164 >ref|NP_624835.1| putative TetR family transcriptional regulator [Streptomyces coelicolor A3(2)] emb|CAB58281.1| putative TetR family transcriptional regulator [Streptomyces coelicolor A3(2)] Length = 193 Score = 78.2 bits (191), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 52/163 (31%), Positives = 83/163 (50%), Gaps = 13/163 (7%) Query: 6 SKEKLQAAATKLFMEKGYENTTVQEIASLAGVTERTFFRQFKDKSDVLFDTNNELGQRVA 65 ++ +L+ AA +L++E+GYE T V EI AG+TERTFFR F DK +VLF + L + + Sbjct: 8 ARGRLEQAALELYVERGYEQTPVAEITKRAGLTERTFFRHFTDKREVLFAGSGRL-EELC 66 Query: 66 AFITDNVDVEKKPLKLAVEGFVSTSXXXXXXXGSRERVLARNQIIQSNPDLQERELLKGQ 125 P++ + + + V R +I SN +L+EREL+K Sbjct: 67 VAAVAAAPTTASPMEAVAAALDAAAGAFEERG---DLVGLRQGVIDSNAELRERELIK-- 121 Query: 126 RLIASVTNSLAATYDS-----DLSELAARFAVGIFHMAFMKWI 163 +AS++ +LA +EL A A+ + +AF +WI Sbjct: 122 --LASLSGALADALRGRGVAEPAAELTAESAIAVLKVAFRRWI 162 >gb|AAK19882.1| putative transcriptional repressor ButR [Streptomyces cinnamonensis] Length = 268 Score = 75.1 bits (183), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 56/194 (28%), Positives = 88/194 (45%), Gaps = 15/194 (7%) Query: 3 KLKSKEKLQAAATKLFMEKGYENTTVQEIASLAGVTERTFFRQFKDKSDVLFDTNNELGQ 62 +LK + +L AAA +LF KGYE TTV EIA+ AGV RTFFR F+ K + +F +++ Sbjct: 28 RLKMRRELAAAAMELFASKGYEATTVDEIAAAAGVARRTFFRHFRSKEEAIFPDHDDTLI 87 Query: 63 RVAAFITDNVDVEKKPLKLAVEGFVSTSXXXXXXXGSRERVLARNQIIQSNPDLQERELL 122 R A + + + PL G S + R ++ + P L+ERE+ Sbjct: 88 RAEAVL-NAAPPHEHPLDTVCRGI---KEVMKMYAASPAVSVERYRLTREVPTLREREIA 143 Query: 123 KGQRLIASVTNSLAATYDSD----------LSELAARFAVGIFHMAFMKWIKSAEKGLAE 172 R T L +D L+E+AA V + +W+++ +G E Sbjct: 144 SVARYERLFTRYLLGHFDEHAHHDGNDDPLLAEVAASAVVTAHNHVLRRWLRAGGQGDVE 203 Query: 173 -QLLTVYELYENSF 185 QL + + +F Sbjct: 204 TQLDHAFAIVRRTF 217 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.317 0.131 0.354 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 224,906,252 Number of extensions: 7567264 Number of successful extensions: 21753 Number of sequences better than 1.0e-05: 19 Number of HSP's gapped: 21767 Number of HSP's successfully gapped: 19 Length of query: 189 Length of database: 757,237,578 Length adjustment: 119 Effective length of query: 70 Effective length of database: 434,140,797 Effective search space: 30389855790 Effective search space used: 30389855790 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 122 (51.6 bits)