BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0535.0019.p (507 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00098053.1| COG1132: ABC-type multidrug transport system,... 583 e-165 ref|ZP_00121326.1| COG1132: ABC-type multidrug transport system,... 488 e-136 ref|NP_695381.1| probable permease protein of ABC transporter sy... 487 e-136 ref|NP_721322.1| putative ABC transporter, ATP-binding protein [... 431 e-119 ref|NP_735838.1| unknown [Streptococcus agalactiae NEM316] >gi|2... 406 e-112 >ref|ZP_00098053.1| COG1132: ABC-type multidrug transport system, ATPase and permease components [Desulfitobacterium hafniense] Length = 586 Score = 583 bits (1504), Expect = e-165, Method: Compositional matrix adjust. Identities = 288/487 (59%), Positives = 354/487 (72%), Gaps = 2/487 (0%) Query: 1 MVKILKYLNPKEWALFGVSFLFIVAQVWLDLELPDYMSEITRLVQTPGSEMSDIIATGGW 60 MV+I KYL +EW + G+S +FIVAQVWLDL+LPDYM+EIT L QTP S +SDI GG+ Sbjct: 1 MVRIFKYLKAEEWLMAGISLIFIVAQVWLDLKLPDYMAEITTLTQTPNSAISDIWLNGGY 60 Query: 61 MLLCALGSLATSXXXXXXXXXXXXNFSSRLRSKLFDKVQSFSMEEINNFSTASLITRSTN 120 MLLCALGSLA + +FS RLRS LF+KV+SFSMEEIN FST+SLITRSTN Sbjct: 61 MLLCALGSLAAAVVVGFFAAKIAASFSQRLRSLLFNKVESFSMEEINRFSTSSLITRSTN 120 Query: 121 DITQVQMLIVIGLQLLVKAPILAVWALLKITGKSWEWSLTTXXXXXXXXXXXXXXXXXXX 180 DITQ+QML+V+GLQL++KAPI AVWA+ KI+GK +EW++ T Sbjct: 121 DITQIQMLVVMGLQLVIKAPITAVWAITKISGKGFEWTMVTGVAVLIMIIMVTFLLIVAL 180 Query: 181 PKFQKLQQLTDNLNRVSRENLTGLRIIRAYNAEGYQENKFSEANNVLTRTNLFANNVLAV 240 PKF+K+Q LTDN+ RV+RENLTGLR++RAYNAE YQE KF AN LT T +F N +AV Sbjct: 181 PKFKKMQTLTDNITRVTRENLTGLRVVRAYNAENYQEEKFETANEELTSTQMFTNRAMAV 240 Query: 241 LMPSITLIMSGLSLAIYWVGASLIQSADMGAKMGLFSDMIVFSSYAIQVVMAXXXXXXXX 300 +MP ++++MSGLSLAIYW+GA LI +A K+GLFS+M+VFSSYA+QV+M+ Sbjct: 241 MMPVMSMLMSGLSLAIYWIGAYLIDAAGALDKLGLFSNMVVFSSYAMQVIMSFMMLVMIF 300 Query: 301 XXXPRAHVSAKRINEVLDTKPSLMNGSLTASSSKLAGEVEFRKVSFKYPDADDYVLKDIS 360 PRA VSAKRINEVLDT+P +++G+ T L GEV F+ VSF+YPDA + VL+DIS Sbjct: 301 IMLPRASVSAKRINEVLDTEPRILDGTKTEGQPGLRGEVVFKSVSFQYPDAAEPVLEDIS 360 Query: 361 FTAKTGETVAFIGSTGCGKSTVVNLIPRFYDATXXXXXXXXXXXXQYEESALRNKMGYVS 420 FTA GETVAFIGSTG GKST+VNL RF+DAT +Y+ AL NK+GYV Sbjct: 361 FTASPGETVAFIGSTGSGKSTLVNLALRFFDATQGEILIDGVNVQEYKLEALFNKIGYVP 420 Query: 421 QKAVLFGGTVTSNIAFGDNGSDASA--EVVDAVYISQASDFVEKMEGSYDAHIAQGGTNL 478 QKAVLF GTV SN+A+GDNG + EV AV I+Q +DFVEKM+G Y A IAQGG N+ Sbjct: 421 QKAVLFKGTVESNVAYGDNGGEGYPLDEVKKAVQIAQGADFVEKMDGQYQAAIAQGGANV 480 Query: 479 SGGQKQR 485 SGGQKQR Sbjct: 481 SGGQKQR 487 >ref|ZP_00121326.1| COG1132: ABC-type multidrug transport system, ATPase and permease components [Bifidobacterium longum DJO10A] Length = 623 Score = 488 bits (1256), Expect = e-136, Method: Compositional matrix adjust. Identities = 250/524 (47%), Positives = 340/524 (64%), Gaps = 39/524 (7%) Query: 1 MVKILKYLNPKEWALFGVSFLFIVAQVWLDLELPDYMSEITRLVQTPGSEMSDIIATGGW 60 M++I+KYL+ E ++ + IV QV+ DL+LPDYMS+IT LV+TPGS+M DI GG Sbjct: 1 MLRIMKYLSKAEIGQMLIALVTIVGQVYFDLKLPDYMSDITTLVETPGSDMKDIWIAGGK 60 Query: 61 MLLCALGSLATSXXXXXXXXXXXXNFSSRLRSKLFDKVQSFSMEEINNFSTASLITRSTN 120 MLL +LGS+A + +F+ RLRS F KV+SF E++ FSTASLITRSTN Sbjct: 61 MLLISLGSVACAIITGYIAARVAASFTQRLRSLEFRKVESFGPAEMSKFSTASLITRSTN 120 Query: 121 DITQVQMLIVIGLQLLVKAPILAVWALLKITGKSWEWSLTTXXXXXXXXXXXXXXXXXXX 180 D+TQVQM I +GLQL+VK+PI+AVWA+ KI G+ +EW+L T Sbjct: 121 DVTQVQMFITMGLQLIVKSPIMAVWAVCKIAGEGFEWTLATGIAVAVLLVSITVMMAMVM 180 Query: 181 PKFQKLQQLTDNLNRVSRENLTGLRIIRAYNAEGYQENKFSEANNVLTRTNLFANNVLAV 240 PKF+ +Q LTDN+N V+RENLTGLR++RAYNAE YQE KF++AN LT T LF N V+A Sbjct: 181 PKFKVMQTLTDNINLVARENLTGLRVVRAYNAEDYQEAKFTKANKDLTETQLFTNRVMAF 240 Query: 241 LMPSITLIMSGLSLAIYWVGASLIQSADMGAKMGLFSDMIVFSSYAIQVVMAXXXXXXXX 300 +MP + +++GL LA+YW+GA LI +A + K+ +FS+M+VFS+Y++QV+M+ Sbjct: 241 MMPLMNTVLNGLMLAVYWIGAYLIDAAGLKDKLTVFSNMVVFSNYSVQVIMSFLLMSMVF 300 Query: 301 XXXPRAHVSAKRINEVLDTKPSLMNGSLTASSSKLAGE---VEFRKVSFKYPDADDYVLK 357 PRA VSA+RI EVLDT+P + NG+ TA+ G+ VEFR VSF YPD+ + +L+ Sbjct: 301 VLWPRADVSAQRIMEVLDTEPIVENGTKTAADVAKTGQRGTVEFRNVSFTYPDSREAMLE 360 Query: 358 DISFTAKTGETVAFIGSTGCGKSTVVNLIPRFYDATXXXXXXXXXXXXQYEESALRNKMG 417 I+FTA+ G+TVAFIGSTG GKS+++NL+PRFYD + Y+ ALR+K+G Sbjct: 361 GINFTAEQGQTVAFIGSTGSGKSSLINLVPRFYDTSQGQVLVDGVDVRDYDLKALRDKIG 420 Query: 418 YVSQKAVLFGGTVTSNIAFGDN-GSDASAEVVD--------------------------- 449 YV Q++VLF GTV SN+++GD G A E+ D Sbjct: 421 YVPQQSVLFRGTVASNVSYGDQPGDPAEVEMADTSTPAGRKREAALIAAGEAAEGADIPA 480 Query: 450 --------AVYISQASDFVEKMEGSYDAHIAQGGTNLSGGQKQR 485 A ++QAS+FV +M+G Y A IAQGG+N+SGGQKQR Sbjct: 481 EQLNRVRAAADVAQASEFVARMDGGYSAAIAQGGSNVSGGQKQR 524 >ref|NP_695381.1| probable permease protein of ABC transporter system [Bifidobacterium longum NCC2705] gb|AAN24017.1| probable permease protein of ABC transporter system [Bifidobacterium longum NCC2705] Length = 623 Score = 487 bits (1254), Expect = e-136, Method: Compositional matrix adjust. Identities = 250/524 (47%), Positives = 339/524 (64%), Gaps = 39/524 (7%) Query: 1 MVKILKYLNPKEWALFGVSFLFIVAQVWLDLELPDYMSEITRLVQTPGSEMSDIIATGGW 60 M +I+KYL+ E ++ + IV QV+ DL+LPDYMS+IT LV+TPGS+M DI GG Sbjct: 1 MFRIMKYLSKAEIGQMLIALVTIVGQVYFDLKLPDYMSDITTLVETPGSDMKDIWIAGGK 60 Query: 61 MLLCALGSLATSXXXXXXXXXXXXNFSSRLRSKLFDKVQSFSMEEINNFSTASLITRSTN 120 MLL +LGS+A + +F+ RLRS F KV+SF E++ FSTASLITRSTN Sbjct: 61 MLLISLGSVACAIITGYIAARVAASFTQRLRSLEFRKVESFGPAEMSKFSTASLITRSTN 120 Query: 121 DITQVQMLIVIGLQLLVKAPILAVWALLKITGKSWEWSLTTXXXXXXXXXXXXXXXXXXX 180 D+TQVQM I +GLQL+VK+PI+AVWA+ KI G+ +EW+L T Sbjct: 121 DVTQVQMFITMGLQLIVKSPIMAVWAVCKIAGEGFEWTLATGIAVAVLLVSITVMMAMVM 180 Query: 181 PKFQKLQQLTDNLNRVSRENLTGLRIIRAYNAEGYQENKFSEANNVLTRTNLFANNVLAV 240 PKF+ +Q LTDN+N V+RENLTGLR++RAYNAE YQE KF++AN LT T LF N V+A Sbjct: 181 PKFKVMQTLTDNINLVARENLTGLRVVRAYNAEDYQEAKFTKANKDLTETQLFTNRVMAF 240 Query: 241 LMPSITLIMSGLSLAIYWVGASLIQSADMGAKMGLFSDMIVFSSYAIQVVMAXXXXXXXX 300 +MP + +++GL LA+YW+GA LI +A + K+ +FS+M+VFS+Y++QV+M+ Sbjct: 241 MMPLMNTVLNGLMLAVYWIGAYLIDAAGLKDKLTVFSNMVVFSNYSVQVIMSFLLMSMVF 300 Query: 301 XXXPRAHVSAKRINEVLDTKPSLMNGSLTASSSKLAGE---VEFRKVSFKYPDADDYVLK 357 PRA VSA+RI EVLDT+P + NG+ TA+ G+ VEFR VSF YPD+ + +L+ Sbjct: 301 VLWPRADVSAQRIMEVLDTEPIVENGTKTAADVAKTGQRGTVEFRNVSFTYPDSREAMLE 360 Query: 358 DISFTAKTGETVAFIGSTGCGKSTVVNLIPRFYDATXXXXXXXXXXXXQYEESALRNKMG 417 I+FTA+ G+TVAFIGSTG GKS+++NL+PRFYD + Y+ ALR+K+G Sbjct: 361 GINFTAEQGQTVAFIGSTGSGKSSLINLVPRFYDTSQGQVLVDGVDVRDYDLKALRDKIG 420 Query: 418 YVSQKAVLFGGTVTSNIAFGDN-GSDASAEVVD--------------------------- 449 YV Q++VLF GTV SN+++GD G A E+ D Sbjct: 421 YVPQQSVLFRGTVASNVSYGDQPGDPAEVEMADTSTPAGRKREAALIAAGEAAEGADIPA 480 Query: 450 --------AVYISQASDFVEKMEGSYDAHIAQGGTNLSGGQKQR 485 A ++QAS+FV +M+G Y A IAQGG+N+SGGQKQR Sbjct: 481 EQLNRVRAAADVAQASEFVARMDGGYSAAIAQGGSNVSGGQKQR 524 >ref|NP_721322.1| putative ABC transporter, ATP-binding protein [Streptococcus mutans UA159] gb|AAN58628.1| putative ABC transporter, ATP-binding protein [Streptococcus mutans UA159] Length = 600 Score = 431 bits (1109), Expect = e-119, Method: Compositional matrix adjust. Identities = 227/499 (45%), Positives = 310/499 (62%), Gaps = 14/499 (2%) Query: 1 MVKILKYLNPKEWALFGVSFLFIVAQVWLDLELPDYMSEITRLVQTPGSEMSDIIATGGW 60 M KI K LN KEW + +S FI VW+DL+ P+YMS IT L+QT G+ SDI+ G Sbjct: 1 MFKIFKRLNAKEWGMVLLSTAFICLAVWMDLKTPEYMSNITTLLQTKGTTASDIMDPGSK 60 Query: 61 MLLCALGSLATSXXXXXXXXXXXXNFSSRLRSKLFDKVQSFSMEEINNFSTASLITRSTN 120 ML+ + GS + +F++RLRS +F++V +S EI FS SL+TR+TN Sbjct: 61 MLMFSFGSFFMAVLVGFLASRTAASFTTRLRSDIFNRVMDYSEAEIKKFSIPSLLTRTTN 120 Query: 121 DITQVQMLIVIGLQLLVKAPILAVWALLKITGKSWEWSLTTXXXXXXXXXXXXXXXXXXX 180 D+TQ+Q++IV+G+Q++ + PI+AVWAL KI GKS EW+ Sbjct: 121 DLTQLQIMIVMGMQVVTRGPIMAVWALTKIWGKSDEWTGAVGVAVLIVFIMLSVLMFVAF 180 Query: 181 PKFQKLQQLTDNLNRVSRENLTGLRIIRAYNAEGYQENKFSEANNVLTRTNLFANNVLAV 240 P+ +++Q LTD LN +RE+LTG+R++RAYNAE YQ+ KF N LT+ NL ++++ Sbjct: 181 PRQRQVQSLTDALNSTTRESLTGVRVVRAYNAEDYQDTKFKRENKNLTKLNLLVYRLMSL 240 Query: 241 LMPSITLIMSGLSLAIYWVGASLIQ---------SADMGA---KMGLFSDMIVFSSYAIQ 288 + P +T++ SGL+LAIYW+GA L+ +A GA ++ +FSDM+VFSSYA+Q Sbjct: 241 MNPVMTVVSSGLTLAIYWIGAYLLNDIKIPMTSVTAAKGAIADRISVFSDMVVFSSYAMQ 300 Query: 289 VVMAXXXXXXXXXXXPRAHVSAKRINEVLDTKPSLMNGSLTASSSKLAGEVEFRKVSFKY 348 VV+ PRA VSAKRINEVL S+ + + + GEVEF VSF+Y Sbjct: 301 VVVGFMMMVAIFIILPRALVSAKRINEVLALNSSVHFKEYSKADNARKGEVEFHDVSFRY 360 Query: 349 PDADDYVLKDISFTAKTGETVAFIGSTGCGKSTVVNLIPRFYDATXXXXXXXXXXXXQYE 408 V++ +SF+AK GETVAFIGSTG GKST+VNLIPRFYDAT Y Sbjct: 361 SKNSRAVIEHVSFSAKAGETVAFIGSTGSGKSTLVNLIPRFYDATEGWIKIDGIKVQDYS 420 Query: 409 ESALRNKMGYVSQKAVLFGGTVTSNIAFG--DNGSDASAEVVDAVYISQASDFVEKMEGS 466 L NK+GY+ Q+AVLF GT+ SNIAFG D A++ +A+ ++QA +FVE+ E Sbjct: 421 HDDLNNKVGYIPQRAVLFSGTIRSNIAFGQSDQAPLDDAKIWEALELAQAKNFVEEKEKG 480 Query: 467 YDAHIAQGGTNLSGGQKQR 485 D +AQGGTN SGGQKQR Sbjct: 481 LDTEVAQGGTNFSGGQKQR 499 >ref|NP_735838.1| unknown [Streptococcus agalactiae NEM316] emb|CAD47060.1| unknown [Streptococcus agalactiae NEM316] Length = 605 Score = 406 bits (1044), Expect = e-112, Method: Compositional matrix adjust. Identities = 212/504 (42%), Positives = 303/504 (60%), Gaps = 19/504 (3%) Query: 1 MVKILKYLNPKEWALFGVSFLFIVAQVWLDLELPDYMSEITRLVQTPGSEMSDIIATGGW 60 M I K LN KEW + S + + VW+DL+ P+YMS+ITR++QT G+++ + G Sbjct: 1 MFNIFKRLNGKEWLMIVASTILVCLAVWMDLKTPEYMSDITRMLQTKGTKLEALWDPGLK 60 Query: 61 MLLCALGSLATSXXXXXXXXXXXXNFSSRLRSKLFDKVQSFSMEEINNFSTASLITRSTN 120 ML + GS + +F+SRLRS +F+ V +S EI FS SL+TR+TN Sbjct: 61 MLAFSFGSFLVAVMVGFLGARTAASFTSRLRSDIFNHVMDYSDAEIKRFSIPSLLTRTTN 120 Query: 121 DITQVQMLIVIGLQLLVKAPILAVWALLKITGKSWEWSLTTXXXXXXXXXXXXXXXXXXX 180 D+TQ+Q+LIV+G+Q++ + PI+A+WAL KI GKS +W+ Sbjct: 121 DLTQLQILIVMGMQVVTRGPIMAIWALTKIWGKSDQWTGAVGVAVIIVMILLSVLLLLAF 180 Query: 181 PKFQKLQQLTDNLNRVSRENLTGLRIIRAYNAEGYQENKFSEANNVLTRTNLFANNVLAV 240 P+ +++Q TD LN +RE L+G+R+IRAYNAE YQ +KF N+ LT+ NLF ++++ Sbjct: 181 PRQRQIQGFTDALNATTREALSGVRVIRAYNAEKYQTDKFKRENDDLTKLNLFVYRLMSL 240 Query: 241 LMPSITLIMSGLSLAIYWVGASLIQSADMGAKMG-----------------LFSDMIVFS 283 + P +T++ SGL+LAIYW+G+ LI + G LFS+M+VFS Sbjct: 241 MNPVMTVVSSGLTLAIYWIGSYLINDISVPKVTGTSVSVLAAKSAITDRVDLFSNMVVFS 300 Query: 284 SYAIQVVMAXXXXXXXXXXXPRAHVSAKRINEVLDTKPSLMNGSLTASSSKLAGEVEFRK 343 SYA+QVVM PRA VSA+RINEVL P++ + S G++EF+ Sbjct: 301 SYAMQVVMGFMMMVAIFIIMPRALVSARRINEVLTLAPTVTFKENSHIQSAQKGQIEFQD 360 Query: 344 VSFKYPDADDYVLKDISFTAKTGETVAFIGSTGCGKSTVVNLIPRFYDATXXXXXXXXXX 403 VSF Y + V++ +SF A TG+TVAFIGSTG GKST+VNL+ RFYDAT Sbjct: 361 VSFHYSKDSEAVIEHVSFKADTGQTVAFIGSTGSGKSTLVNLVTRFYDATEGAIKLDGID 420 Query: 404 XXQYEESALRNKMGYVSQKAVLFGGTVTSNIAFGDNGSD--ASAEVVDAVYISQASDFVE 461 +Y + L NK+GY+ QKAVLF GTV SN+ G++G + + E+ A+ ++QA +F+E Sbjct: 421 IKEYSHNDLNNKIGYIPQKAVLFSGTVRSNMILGESGREELSDEEIWQALELAQAKEFIE 480 Query: 462 KMEGSYDAHIAQGGTNLSGGQKQR 485 E D +AQGG+N SGGQKQR Sbjct: 481 AKEKGLDTEVAQGGSNFSGGQKQR 504 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.318 0.132 0.371 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 591,252,378 Number of extensions: 19983971 Number of successful extensions: 91762 Number of sequences better than 1.0e-05: 3467 Number of HSP's gapped: 86683 Number of HSP's successfully gapped: 3772 Length of query: 507 Length of database: 757,237,578 Length adjustment: 130 Effective length of query: 377 Effective length of database: 404,274,708 Effective search space: 152411564916 Effective search space used: 152411564916 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 128 (53.9 bits)