BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0535.0017.p (351 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00062576.1| COG0642: Signal transduction histidine kinase... 199 9e-50 ref|NP_978357.1| sensor histidine kinase [Bacillus cereus ATCC 1... 190 4e-47 ref|NP_831727.1| Two component system histidine kinase [Bacillus... 188 1e-46 ref|NP_655820.1| HATPase_c, Histidine kinase-, DNA gyrase B-, ph... 185 2e-45 ref|NP_844364.1| sensor histidine kinase [Bacillus anthracis str... 185 2e-45 >ref|ZP_00062576.1| COG0642: Signal transduction histidine kinase [Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293] Length = 355 Score = 199 bits (506), Expect = 9e-50, Method: Compositional matrix adjust. Identities = 109/271 (40%), Positives = 160/271 (59%), Gaps = 6/271 (2%) Query: 84 IREFIEATQRLAAGDFSTRLYLKSPPE-YRILS---ENFNRMAEELGSIEILRTDFVNNF 139 + + EAT+++A GDFS L E Y L ENFN M EELGS E L+ DF+ N Sbjct: 81 VSQLNEATRQVAQGDFSVYLEPGHAREKYNDLDYVFENFNLMIEELGSTETLKNDFIANV 140 Query: 140 SHEFKTPIVSIKGFAEILKYDDLSEEERDEYLDIVIEESARLASLASNVLELSKIETQTI 199 SHEFK P+ I+ +AE LK ++ EE+RD Y I+++E+ ++A++ +NVL+LSKIE Q + Sbjct: 141 SHEFKAPLAVIRSYAEALK-NETDEEQRDMYTQIIVDETDKMATMVTNVLKLSKIENQAL 199 Query: 200 LTDKQEVNVGEQIRQCVXXXXXXXXXXXXXXNLGL-HDYSLSGNKEMLNQVWLNLLENAV 258 ++ NV Q+ + + ++ + D ++ + EM+ VW NLL NA Sbjct: 200 QPHIKKYNVSRQLVETLLNFEKIWASHNISLDINIPDDIEIAADPEMMELVWQNLLSNAF 259 Query: 259 KFTPEQGTVTIEMKRTANSLEMVFSNTGSVIDPETLPRIFDKFYQADTSHATVGNGLGLT 318 KF P G VT+ +++ E+ + G +D TL RIFDKFYQ +TSH GNGLGL+ Sbjct: 260 KFVPSDGQVTLRLQQNNEGTEITVRDNGEGMDHNTLNRIFDKFYQGETSHTNQGNGLGLS 319 Query: 319 IVQRIVNLHGGTVACESGPLQGTVFIVTLPF 349 +V RIV L G+++ ES +G+ F V LP Sbjct: 320 LVNRIVTLMQGSISVESKLGKGSAFTVWLPL 350 >ref|NP_978357.1| sensor histidine kinase [Bacillus cereus ATCC 10987] gb|AAS40965.1| sensor histidine kinase [Bacillus cereus ATCC 10987] Length = 351 Score = 190 bits (482), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 101/274 (36%), Positives = 170/274 (62%), Gaps = 7/274 (2%) Query: 79 SMVKTIREFIEATQRLAAGDFSTRLY--LKSPPEYRILSENFNRMAEELGSIEILRTDFV 136 +M+ TI IE Q++A GDFS ++ K E +L ++ N M +EL ++E +R +FV Sbjct: 76 AMIWTI---IEPIQKIAKGDFSVKIRNEEKYDGEIGVLVKSINDMTDELNAMEKMRQEFV 132 Query: 137 NNFSHEFKTPIVSIKGFAEILKYDDLSEEERDEYLDIVIEESARLASLASNVLELSKIET 196 +N SHE ++P+ SIKGFA L+ ++LSEE+R+ YL I+ E+ RL+ L+ N+L+L+ +E+ Sbjct: 133 SNVSHEIQSPLTSIKGFARALQDNNLSEEKREHYLTIIETETTRLSKLSQNLLKLTLLES 192 Query: 197 QTILTDKQEVNVGEQIRQCVXXXXXXXXXXXXXXNLGLHDYSLSGNKEMLNQVWLNLLEN 256 + ++ + +Q++Q V L L ++ ++E ++QVW+NL+ N Sbjct: 193 EEYTPERATYRLDQQLKQIVLNSEPLWAEKEIELELNLEKVHITADQESMSQVWINLIHN 252 Query: 257 AVKFTPEQGTVTIEMKRTANSLEMVFSNTGSVIDPETLPRIFDKFYQADTS--HATVGNG 314 ++KFTP GT+TI++K +E+ ++G I E IF++FY+AD+S A G+G Sbjct: 253 SIKFTPNGGTITIQLKEYEKVVEVRIRDSGIGISKEQKQHIFERFYKADSSRNRAYGGSG 312 Query: 315 LGLTIVQRIVNLHGGTVACESGPLQGTVFIVTLP 348 LGL IV+++++LH G + ES +GT FIV +P Sbjct: 313 LGLAIVKKVLDLHQGEIKVESEEGKGTEFIVCIP 346 >ref|NP_831727.1| Two component system histidine kinase [Bacillus cereus ATCC 14579] gb|AAP08928.1| Two component system histidine kinase [Bacillus cereus ATCC 14579] Length = 348 Score = 188 bits (478), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 102/274 (37%), Positives = 168/274 (61%), Gaps = 7/274 (2%) Query: 79 SMVKTIREFIEATQRLAAGDFSTRLY--LKSPPEYRILSENFNRMAEELGSIEILRTDFV 136 +M+ TI IE Q++A GDFS ++ K E +L ++ N M +EL ++E +R +FV Sbjct: 73 AMIWTI---IEPIQKIAKGDFSVKIRNEEKYDGEIGVLVKSINDMTDELNTMEKMRQEFV 129 Query: 137 NNFSHEFKTPIVSIKGFAEILKYDDLSEEERDEYLDIVIEESARLASLASNVLELSKIET 196 +N SHE ++P+ SIKGFA L+ D+LSEE+R YL I+ E+ RL+ L+ N+L+L+ +E+ Sbjct: 130 SNVSHEIQSPLTSIKGFARALQDDNLSEEKRKHYLTIIETETTRLSKLSQNLLKLTLLES 189 Query: 197 QTILTDKQEVNVGEQIRQCVXXXXXXXXXXXXXXNLGLHDYSLSGNKEMLNQVWLNLLEN 256 + ++ + +Q++Q V L L + ++E ++QVW+NL+ N Sbjct: 190 EEYTPERVSYRLDQQLKQIVLNSEPLWAEKEIELELDLEKVYVIADQESMSQVWINLIHN 249 Query: 257 AVKFTPEQGTVTIEMKRTANSLEMVFSNTGSVIDPETLPRIFDKFYQADTS--HATVGNG 314 ++KFTP GT+TI++K +E+ ++G I E IF++FY+AD+S A G+G Sbjct: 250 SIKFTPSGGTITIQLKEHETVVEVRIRDSGIGISEEQKQHIFERFYKADSSRNRAYGGSG 309 Query: 315 LGLTIVQRIVNLHGGTVACESGPLQGTVFIVTLP 348 LGL IV+++++LH G + ES +GT FIV +P Sbjct: 310 LGLAIVKKVLDLHHGEIKVESEEGKGTEFIVRMP 343 >ref|NP_655820.1| HATPase_c, Histidine kinase-, DNA gyrase B-, phytochrome-like ATPase [Bacillus anthracis A2012] Length = 357 Score = 185 bits (469), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 100/274 (36%), Positives = 167/274 (60%), Gaps = 7/274 (2%) Query: 79 SMVKTIREFIEATQRLAAGDFSTRLY--LKSPPEYRILSENFNRMAEELGSIEILRTDFV 136 +M+ TI IE Q++A GDFS ++ K E +L ++ N M +EL ++E +R +FV Sbjct: 82 AMIWTI---IEPIQKIAKGDFSVKIRNEEKYDGEIGVLVKSINDMTDELNAMEKMRQEFV 138 Query: 137 NNFSHEFKTPIVSIKGFAEILKYDDLSEEERDEYLDIVIEESARLASLASNVLELSKIET 196 +N SHE ++P+ SIKGFA L+ +L EE+R YL I+ E+ RL+ L+ N+L+L+ +E+ Sbjct: 139 SNVSHEIQSPLTSIKGFARALQDTNLPEEKRKHYLTIIETETTRLSKLSQNLLKLTLLES 198 Query: 197 QTILTDKQEVNVGEQIRQCVXXXXXXXXXXXXXXNLGLHDYSLSGNKEMLNQVWLNLLEN 256 + ++ + +Q++Q V +L L ++ ++E ++QVW+NL+ N Sbjct: 199 EEYTPERVTYRLDQQLKQIVLNSEPLWAEKEIELDLDLEKVHITADQESMSQVWINLIHN 258 Query: 257 AVKFTPEQGTVTIEMKRTANSLEMVFSNTGSVIDPETLPRIFDKFYQADTS--HATVGNG 314 ++KFTP GT++I++K +E+ +TGS I E IF++FY+AD+S A G+G Sbjct: 259 SIKFTPSSGTISIKLKEYETLVEVRIRDTGSGISEEQKQHIFERFYKADSSRNRAYGGSG 318 Query: 315 LGLTIVQRIVNLHGGTVACESGPLQGTVFIVTLP 348 LGL IV+++++LH G + ES GT IV +P Sbjct: 319 LGLAIVKKVLDLHQGEIKVESEEGNGTECIVCIP 352 >ref|NP_844364.1| sensor histidine kinase [Bacillus anthracis str. Ames] gb|AAP25850.1| sensor histidine kinase [Bacillus anthracis str. Ames] Length = 351 Score = 185 bits (469), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 100/274 (36%), Positives = 167/274 (60%), Gaps = 7/274 (2%) Query: 79 SMVKTIREFIEATQRLAAGDFSTRLY--LKSPPEYRILSENFNRMAEELGSIEILRTDFV 136 +M+ TI IE Q++A GDFS ++ K E +L ++ N M +EL ++E +R +FV Sbjct: 76 AMIWTI---IEPIQKIAKGDFSVKIRNEEKYDGEIGVLVKSINDMTDELNAMEKMRQEFV 132 Query: 137 NNFSHEFKTPIVSIKGFAEILKYDDLSEEERDEYLDIVIEESARLASLASNVLELSKIET 196 +N SHE ++P+ SIKGFA L+ +L EE+R YL I+ E+ RL+ L+ N+L+L+ +E+ Sbjct: 133 SNVSHEIQSPLTSIKGFARALQDTNLPEEKRKHYLTIIETETTRLSKLSQNLLKLTLLES 192 Query: 197 QTILTDKQEVNVGEQIRQCVXXXXXXXXXXXXXXNLGLHDYSLSGNKEMLNQVWLNLLEN 256 + ++ + +Q++Q V +L L ++ ++E ++QVW+NL+ N Sbjct: 193 EEYTPERVTYRLDQQLKQIVLNSEPLWAEKEIELDLDLEKVHITADQESMSQVWINLIHN 252 Query: 257 AVKFTPEQGTVTIEMKRTANSLEMVFSNTGSVIDPETLPRIFDKFYQADTS--HATVGNG 314 ++KFTP GT++I++K +E+ +TGS I E IF++FY+AD+S A G+G Sbjct: 253 SIKFTPSSGTISIKLKEYETLVEVRIRDTGSGISEEQKQHIFERFYKADSSRNRAYGGSG 312 Query: 315 LGLTIVQRIVNLHGGTVACESGPLQGTVFIVTLP 348 LGL IV+++++LH G + ES GT IV +P Sbjct: 313 LGLAIVKKVLDLHQGEIKVESEEGNGTECIVCIP 346 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.135 0.376 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 411,403,441 Number of extensions: 14661782 Number of successful extensions: 63091 Number of sequences better than 1.0e-05: 4233 Number of HSP's gapped: 57100 Number of HSP's successfully gapped: 4267 Length of query: 351 Length of database: 757,237,578 Length adjustment: 126 Effective length of query: 225 Effective length of database: 415,135,104 Effective search space: 93405398400 Effective search space used: 93405398400 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 126 (53.1 bits)