BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0535.0016.p (238 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_734591.1| Unknown [Streptococcus agalactiae NEM316] >gi|2... 222 4e-57 ref|NP_687159.1| DNA-binding response regulator [Streptococcus a... 222 6e-57 ref|ZP_00062577.1| COG0745: Response regulators consisting of a ... 212 7e-54 ref|NP_472057.1| similar to two-component response regulator [Li... 205 9e-52 ref|NP_466106.1| similar to two-component response regulator [Li... 203 3e-51 >ref|NP_734591.1| Unknown [Streptococcus agalactiae NEM316] emb|CAD45766.1| Unknown [Streptococcus agalactiae NEM316] Length = 223 Score = 222 bits (566), Expect = 4e-57, Method: Compositional matrix adjust. Identities = 103/220 (46%), Positives = 154/220 (70%) Query: 12 MIHILVVEDDRHARRLLEAVLKREGYLVSTAEDGARAMDVLDQQHIDLIVLDIMMPNMDG 71 MI ILVVED+ ++++ L +EGY TA +G A++ LD + + LI+ DIMMP MDG Sbjct: 1 MIKILVVEDNIVQQKIITTKLTQEGYQFITASNGQEALNCLDTEEVQLIITDIMMPMMDG 60 Query: 72 YEFAKELRDAGSLIPVLMATAKHLPEDKKKGFRLGIDDYMTKPVDTEEMLLRIGALLRRS 131 Y+ +ELR A +P+++ TAK ED KGF LG DDYM KPV +E+ LRI ALLRR+ Sbjct: 61 YQLIQELRSAAYNVPIIVMTAKSQMEDMTKGFGLGADDYMVKPVQLQELALRIKALLRRA 120 Query: 132 QIASARKLVVGNVVLDYDALTVTRGEEKQTLPQKEFYLLYKLLSYPDRIFTRIQLMDEIW 191 I + +L++GN L+ D L++ E++ PQKEF +L+ LLSYP+RIFTR++L+D IW Sbjct: 121 NIVAQHQLIIGNTCLNEDELSLKYFEQEIVFPQKEFRVLFHLLSYPNRIFTRLELLDSIW 180 Query: 192 GMESESSDTTVNVHINRLRKRFEGYPEFELVSVRGLGYKA 231 GM+++ + V+ IN++R++ E P+F++ +VRG+GY+A Sbjct: 181 GMDTDLDERVVDACINKIRRKVEHLPDFKIETVRGVGYRA 220 >ref|NP_687159.1| DNA-binding response regulator [Streptococcus agalactiae 2603V/R] gb|AAM99031.1| DNA-binding response regulator [Streptococcus agalactiae 2603V/R] Length = 223 Score = 222 bits (565), Expect = 6e-57, Method: Compositional matrix adjust. Identities = 103/220 (46%), Positives = 154/220 (70%) Query: 12 MIHILVVEDDRHARRLLEAVLKREGYLVSTAEDGARAMDVLDQQHIDLIVLDIMMPNMDG 71 MI ILVVED+ ++++ L +EGY TA +G A++ LD + + LI+ DIMMP MDG Sbjct: 1 MIKILVVEDNIVQQKIITTKLTQEGYQFITASNGQEALNCLDTEEVQLIITDIMMPMMDG 60 Query: 72 YEFAKELRDAGSLIPVLMATAKHLPEDKKKGFRLGIDDYMTKPVDTEEMLLRIGALLRRS 131 Y+ +ELR A +P+++ TAK ED KGF LG DDYM KPV +E+ LRI ALLRR+ Sbjct: 61 YQLIQELRSAAYNVPIIVMTAKSQMEDMTKGFGLGADDYMVKPVQLQELALRIKALLRRA 120 Query: 132 QIASARKLVVGNVVLDYDALTVTRGEEKQTLPQKEFYLLYKLLSYPDRIFTRIQLMDEIW 191 I + +L++GN L+ D L++ E++ PQKEF +L+ LLSYP+RIFTR++L+D IW Sbjct: 121 NIVAQHQLIIGNTCLNEDELSLKYFEQEIIFPQKEFRVLFHLLSYPNRIFTRLELLDSIW 180 Query: 192 GMESESSDTTVNVHINRLRKRFEGYPEFELVSVRGLGYKA 231 GM+++ + V+ IN++R++ E P+F++ +VRG+GY+A Sbjct: 181 GMDTDLDERVVDACINKIRRKVEHLPDFKIETVRGVGYRA 220 >ref|ZP_00062577.1| COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293] Length = 223 Score = 212 bits (539), Expect = 7e-54, Method: Compositional matrix adjust. Identities = 99/221 (44%), Positives = 149/221 (67%) Query: 12 MIHILVVEDDRHARRLLEAVLKREGYLVSTAEDGARAMDVLDQQHIDLIVLDIMMPNMDG 71 M +I+VVEDD + R+L L G+ V +A A D + Q D+I+ D+MMPN+DG Sbjct: 1 MANIIVVEDDPNFNRILSIYLSNHGHQVQSALGAQEAYDKMYNQLFDMILSDVMMPNIDG 60 Query: 72 YEFAKELRDAGSLIPVLMATAKHLPEDKKKGFRLGIDDYMTKPVDTEEMLLRIGALLRRS 131 +EF + +R IP+L TAK + K++GF GIDDYM KP+D EML+R+ ALLRR+ Sbjct: 61 FEFTETVRKINPNIPILFVTAKDDIQSKQRGFSSGIDDYMVKPIDMSEMLMRVTALLRRA 120 Query: 132 QIASARKLVVGNVVLDYDALTVTRGEEKQTLPQKEFYLLYKLLSYPDRIFTRIQLMDEIW 191 +A+ RKL +GN VLD D++++ ++ ++ +EF +L+KLLSYP++ F+R QL+DE W Sbjct: 121 HVANDRKLTIGNTVLDADSVSIMVDSQEISVTVREFNILFKLLSYPNKTFSRSQLLDEFW 180 Query: 192 GMESESSDTTVNVHINRLRKRFEGYPEFELVSVRGLGYKAV 232 G+++ + V+V+I +LR +F G FE+ +V GLGYKAV Sbjct: 181 GVDTTTGLRAVDVYITKLRDKFSGSDVFEITTVHGLGYKAV 221 >ref|NP_472057.1| similar to two-component response regulator [Listeria innocua] pir||AB1773 two-component response regulator homolog lin2728 [imported] - Listeria innocua (strain Clip11262) emb|CAC97954.1| lin2728 [Listeria innocua] Length = 225 Score = 205 bits (521), Expect = 9e-52, Method: Compositional matrix adjust. Identities = 104/220 (47%), Positives = 146/220 (66%), Gaps = 1/220 (0%) Query: 12 MIHILVVEDDRHARRLLEAVLKREGYLVSTAEDGARAMDVLDQQHIDLIVLDIMMPNMDG 71 M ILVV+DDRH +L+ L+ EG+ V A DG +++ + + L V+D+MMPNMDG Sbjct: 1 MKQILVVDDDRHILKLVGHYLRAEGFHVLEASDGVEGEKIVETEQVHLAVIDVMMPNMDG 60 Query: 72 YEFAKELRDAGSLIPVLMATAKHLPEDKKKGFRLGIDDYMTKPVDTEEMLLRIGALLRRS 131 +E K+LR + IPV+M TAK DK +GF +G DDY+TKP + EE++ RI ALLRRS Sbjct: 61 FELCKKLRISYPDIPVIMLTAKDALADKSRGFEVGTDDYVTKPFEPEELIFRIRALLRRS 120 Query: 132 QIASARKLVVGNVVLDYDALTVTRGEEKQTLPQKEFYLLYKLLSYPDRIFTRIQLMDEIW 191 AS K+ +GN+ +D + + G +++ +P KEF LLY+L SYP RIFTR +L++ IW Sbjct: 121 NQASEAKITIGNITIDQKSYGIKIGNQERMIPVKEFELLYQLASYPGRIFTREELIERIW 180 Query: 192 GMESESSDTTVNVHINRLRKRF-EGYPEFELVSVRGLGYK 230 + + SD TV+VHI RLR F E +V+VRG+GYK Sbjct: 181 QRDYDGSDRTVDVHIKRLRDHFDEEKDGIRIVTVRGVGYK 220 >ref|NP_466106.1| similar to two-component response regulator [Listeria monocytogenes EGD-e] pir||AG1397 two-component response regulator homolog lmo2583 [imported] - Listeria monocytogenes (strain EGD-e) emb|CAD00661.1| lmo2583 [Listeria monocytogenes] Length = 225 Score = 203 bits (516), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 103/220 (46%), Positives = 147/220 (66%), Gaps = 1/220 (0%) Query: 12 MIHILVVEDDRHARRLLEAVLKREGYLVSTAEDGARAMDVLDQQHIDLIVLDIMMPNMDG 71 M ILVV+DDRH +L+ L+ EG+ V A DG A +++ + + L V+D+MMPNMDG Sbjct: 1 MKQILVVDDDRHILKLVGHYLRAEGFHVLEASDGVEAEKIVETEQVHLAVIDVMMPNMDG 60 Query: 72 YEFAKELRDAGSLIPVLMATAKHLPEDKKKGFRLGIDDYMTKPVDTEEMLLRIGALLRRS 131 +E +++R + IPV+M TAK DK +GF +G DDY+TKP + EE++ RI ALLRRS Sbjct: 61 FELCQKMRASYPDIPVIMLTAKDALADKSRGFEVGTDDYVTKPFEPEELIFRIRALLRRS 120 Query: 132 QIASARKLVVGNVVLDYDALTVTRGEEKQTLPQKEFYLLYKLLSYPDRIFTRIQLMDEIW 191 AS K+ +GN+ +D + + G +++ +P KEF LLY+L SYP RIFTR +L++ IW Sbjct: 121 NQASEVKINIGNITIDQKSYGIKIGNQERMIPVKEFELLYQLASYPGRIFTREELIERIW 180 Query: 192 GMESESSDTTVNVHINRLRKRF-EGYPEFELVSVRGLGYK 230 + + SD TV+VHI RLR F E +V+VRG+GYK Sbjct: 181 QRDYDGSDRTVDVHIKRLRDHFDEEKDGIRIVTVRGVGYK 220 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.321 0.138 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 327,301,374 Number of extensions: 12608978 Number of successful extensions: 46707 Number of sequences better than 1.0e-05: 6000 Number of HSP's gapped: 42029 Number of HSP's successfully gapped: 6105 Length of query: 238 Length of database: 757,237,578 Length adjustment: 122 Effective length of query: 116 Effective length of database: 425,995,500 Effective search space: 49415478000 Effective search space used: 49415478000 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 124 (52.4 bits)