BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0530.0016.p (195 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_782435.1| transcriptional regulator [Clostridium tetani E... 159 3e-38 ref|NP_720952.1| putative transcriptional regulator [Streptococc... 128 9e-29 ref|NP_721922.1| putative transcriptional regulator [Streptococc... 100 2e-20 ref|NP_561293.1| probable transcriptional regulator [Clostridium... 100 3e-20 ref|NP_654899.1| tetR, Bacterial regulatory proteins, tetR famil... 86 3e-16 >ref|NP_782435.1| transcriptional regulator [Clostridium tetani E88] gb|AAO36372.1| transcriptional regulator [Clostridium tetani E88] Length = 185 Score = 159 bits (402), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 79/185 (42%), Positives = 112/185 (60%), Gaps = 6/185 (3%) Query: 7 SQVTKNALAHSLKKLMLTKPLHKITIQQLTDDCGVTRHTFYNHFQDIYELLGWVYQTEII 66 S +TK LA+SLKKLM KPL KITI+ +T DC V R TFY HFQDIY+LL W+Y+TE I Sbjct: 2 SLMTKKELANSLKKLMSIKPLDKITIKDITADCNVNRQTFYYHFQDIYDLLDWIYKTEAI 61 Query: 67 EDLEQYRNCAGWKQGFLSVLYYTQNNKTICLNTFHSLGREHLESFLXXXXXXXXXXXXXX 126 + + +Y+ W++GFL + Y +NK C+N+ HSLGR+HL++FL Sbjct: 62 DGISEYKTYKTWQKGFLMIFQYIIHNKEFCINSLHSLGRDHLDNFLYKFTFDLLMEVINE 121 Query: 127 LDAREPERADV--QAKQEIADFYTLAILGQVIHWLKAGADSDPAWIVAKVARIMDGSISR 184 + E DV + K+ IA+FYT A + +I W+K G P I+ K+ +++G I + Sbjct: 122 V----SEGMDVLNEDKKFIANFYTYAFVNLLIMWMKNGMKESPEIIIEKLNTLIEGDIEK 177 Query: 185 GLANY 189 L Y Sbjct: 178 ALKKY 182 >ref|NP_720952.1| putative transcriptional regulator [Streptococcus mutans UA159] gb|AAN58258.1| putative transcriptional regulator [Streptococcus mutans UA159] Length = 188 Score = 128 bits (321), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 66/183 (36%), Positives = 102/183 (55%), Gaps = 2/183 (1%) Query: 7 SQVTKNALAHSLKKLMLTKPLHKITIQQLTDDCGVTRHTFYNHFQDIYELLGWVYQTEII 66 SQ TK AL SLK L+L KPL KITIQ +TDDCG++R TFY HF+DIY+L+ WV Sbjct: 2 SQTTKKALEDSLKHLLLQKPLPKITIQDITDDCGISRMTFYYHFKDIYDLIEWVCIENAS 61 Query: 67 EDLEQYRNCAGWKQGFLSVLYYTQNNKTICLNTFHSLGREHLESFLXXXXXXXXXXXXXX 126 + L + ++ W++G L + NK +N +HS+ RE +E++L Sbjct: 62 QALGENKDYETWEEGLLRIFNAVIANKPFIMNVYHSVSREQIETYLYTLTYDLMINVVN- 120 Query: 127 LDAREPERADVQAKQEIADFYTLAILGQVIHWLKAGADSDPAWIVAKVARIMDGSISRGL 186 + + + + + K IADFY A++G ++ W++ DP IV + ++ G+I L Sbjct: 121 -EKAKGLKVNDEEKNFIADFYKFALVGLMLDWIRKDMKEDPRIIVKHLDSLVHGNIVTAL 179 Query: 187 ANY 189 +Y Sbjct: 180 HHY 182 >ref|NP_721922.1| putative transcriptional regulator [Streptococcus mutans UA159] gb|AAN59228.1| putative transcriptional regulator [Streptococcus mutans UA159] Length = 174 Score = 100 bits (249), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 50/175 (28%), Positives = 92/175 (52%), Gaps = 4/175 (2%) Query: 7 SQVTKNALAHSLKKLMLTKPLHKITIQQLTDDCGVTRHTFYNHFQDIYELLGWVYQTEII 66 + +T+ A A +LK++M K K+T+ +L V R TFY HF+D+Y+LL W+Y T+ Sbjct: 2 NNLTEQAFARALKEIMAKKSFDKVTVTELVRFLNVNRQTFYYHFKDLYDLLEWIYITDGE 61 Query: 67 EDLEQYRNCAGWKQGFLSVLYYTQNNKTICLNTFHSLGREHLESFLXXXXXXXXXXXXXX 126 + + R A W++G L++ Y Q+N+ NT+HS+ R +LE FL Sbjct: 62 KMIGDKRTTASWQEGLLAIFQYIQDNEAFVRNTYHSINRNYLEHFLYDRAYSLIRPVIEE 121 Query: 127 LDAR-EPERADVQAKQEIADFYTLAILGQVIHWLKAGADSDPAWIVAKVARIMDG 180 + + + AD+ + A FY ++G ++ W+ +G P + ++ +++ Sbjct: 122 NEIQTQISEADIDLR---AHFYKYGLVGFILDWIDSGLREKPEDLTQRIYHLLES 173 >ref|NP_561293.1| probable transcriptional regulator [Clostridium perfringens] dbj|BAB80083.1| probable transcriptional regulator [Clostridium perfringens str. 13] Length = 192 Score = 99.8 bits (247), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 50/180 (27%), Positives = 93/180 (51%), Gaps = 4/180 (2%) Query: 8 QVTKNALAHSLKKLMLTKPLHKITIQQLTDDCGVTRHTFYNHFQDIYELLGWVYQTEIIE 67 Q TK + +L+ +PL+KIT++ + CG+ R+TFY ++ D+YELL ++QTE+ Sbjct: 4 QYTKKMIRSVFIELLNERPLNKITVKDIALACGINRNTFYYYYSDMYELLSELFQTELQN 63 Query: 68 DLEQYRNCAGWKQGFLSVLYYTQNNKTICLNTFHSLGREHLESFLXXXXXXXXXXXXXXL 127 +++Y + W++ F+ + NK + + ++S+ RE L +++ L Sbjct: 64 VIDEYNDTMSWEESFVLATRFALGNKKVIYHVYNSMQREELVNYIYNVSGNMMERYVKKL 123 Query: 128 D-AREPERADVQAKQEIADFYTLAILGQVIHWLKAGADSDPAWIVAKVARIMDGSISRGL 186 D++ IA FY A+ VI W+ +G DP I+ ++ ++ DG+I L Sbjct: 124 SHGINASEYDMKL---IATFYQCALTEMVIQWISSGMKEDPDAIIRRIGKLFDGNIKLSL 180 >ref|NP_654899.1| tetR, Bacterial regulatory proteins, tetR family [Bacillus anthracis A2012] ref|NP_843469.1| conserved hypothetical protein [Bacillus anthracis str. Ames] gb|AAP24955.1| conserved hypothetical protein [Bacillus anthracis str. Ames] Length = 188 Score = 86.3 bits (212), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 46/177 (25%), Positives = 85/177 (48%) Query: 4 MSYSQVTKNALAHSLKKLMLTKPLHKITIQQLTDDCGVTRHTFYNHFQDIYELLGWVYQT 63 M+ S ++K +A+SLK LM T+ HKI++ + C + R TFY HF+D +ELLGW+Y+ Sbjct: 1 MTSSIISKKIIANSLKYLMETESFHKISVSDIMLHCQMRRQTFYYHFKDKFELLGWIYRE 60 Query: 64 EIIEDLEQYRNCAGWKQGFLSVLYYTQNNKTICLNTFHSLGREHLESFLXXXXXXXXXXX 123 E E++ + + W+ F + Y N+ N F + + +L Sbjct: 61 ETKENIIDFLDYETWENIFDLLFDYFYENQKFYRNAFKVIEQNSFNHYLFEHTKNLYMKI 120 Query: 124 XXXLDAREPERADVQAKQEIADFYTLAILGQVIHWLKAGADSDPAWIVAKVARIMDG 180 L + K IA FY+ +G + W+++ + DP+ + + + +++ Sbjct: 121 IDELSVSCGFSLSDETKNTIASFYSHGFVGTIKDWIESKCEVDPSIMSSLMKNMINN 177 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.321 0.134 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 264,202,328 Number of extensions: 9520868 Number of successful extensions: 18508 Number of sequences better than 1.0e-05: 21 Number of HSP's gapped: 18500 Number of HSP's successfully gapped: 21 Length of query: 195 Length of database: 757,237,578 Length adjustment: 119 Effective length of query: 76 Effective length of database: 434,140,797 Effective search space: 32994700572 Effective search space used: 32994700572 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 122 (51.6 bits)