BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0521.0006.p (234 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_781509.1| transcriptional regulatory protein [Clostridium... 240 2e-62 ref|NP_562109.1| two-component response regulator [Clostridium p... 229 3e-59 pir||I40084 gtcR protein - Bacillus brevis >gi|468745|emb|CAA552... 228 9e-59 ref|NP_830149.1| Two-component response regulator [Bacillus cere... 225 5e-58 ref|NP_842823.1| DNA-binding response regulator [Bacillus anthra... 225 7e-58 >ref|NP_781509.1| transcriptional regulatory protein [Clostridium tetani E88] gb|AAO35446.1| transcriptional regulatory protein [Clostridium tetani E88] Length = 230 Score = 240 bits (612), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 123/228 (53%), Positives = 166/228 (72%), Gaps = 3/228 (1%) Query: 3 TILIADDELEIVELLQLYLEKE-YNILQAQNGNEALKLMQSHTVDLAILDIMMPGMDGLQ 61 ILIA+DE +I ELL L+L KE YN+ +A NG EAL + + +DLAILDIMMPG+DG + Sbjct: 2 NILIAEDEQDIRELLGLHLIKEDYNVYEACNGIEALDVFNKNDIDLAILDIMMPGLDGFK 61 Query: 62 LLKRIRENDHFPVLFLSAKSQYHDKILGLELGADDYISKPFNPLEIVARVGSMLRRVHEF 121 +LK+IRE + PV+F++A+ + +KILGL LGADDYI KPF+P+E+VARV ++ RRV + Sbjct: 62 VLKKIREKSNIPVIFITARGEDENKILGLGLGADDYIVKPFSPMEVVARVKALFRRVGTY 121 Query: 122 DAPAVQEKKKEQIVLGRLLLDRSSCQVEVDGEPVALTSTEYKILELLMEQPGRVFTRKKI 181 + ++ K I G L L++ SC +G P+ L + EYKI+E LME GRV T+K+I Sbjct: 122 SQNSSKDINK--IENGELSLNKDSCTFYKNGNPIELNAKEYKIMEFLMENKGRVHTKKQI 179 Query: 182 YEAVWEDFYVYEDNSIMVHISNIRDKIERDSKKPEYLKTIRGLGYKIE 229 YE VW Y + N+IMVHIS+IRDKIE + K+P YLKTIRG+GYK+E Sbjct: 180 YEKVWGYEYYGDANTIMVHISHIRDKIEDNPKEPIYLKTIRGIGYKLE 227 >ref|NP_562109.1| two-component response regulator [Clostridium perfringens] dbj|BAB80899.1| two-component response regulator [Clostridium perfringens str. 13] Length = 225 Score = 229 bits (585), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 118/228 (51%), Positives = 162/228 (71%), Gaps = 7/228 (3%) Query: 3 TILIADDELEIVELLQLYLEKE-YNILQAQNGNEALKLMQSHTVDLAILDIMMPGMDGLQ 61 ILIA+DE +I LL+L+L KE Y + +A NG EAL +++ + LA+LD+MM G+DG Sbjct: 2 NILIAEDEQDIRNLLELHLLKEGYTVFKAVNGLEALDILKKEHIHLALLDVMMDGIDGFN 61 Query: 62 LLKRIRENDHFPVLFLSAKSQYHDKILGLELGADDYISKPFNPLEIVARVGSMLRRVHEF 121 LLK +RE PV+FL+AK + DKILGL LGADDY+ KPF P+E++AR+ S LRR +++ Sbjct: 62 LLKMLREWSQIPVIFLTAKIEDDDKILGLGLGADDYVIKPFKPVELMARIKSNLRRCYKY 121 Query: 122 DAPAVQEKKKEQIVLGRLLLDRSSCQVEVDGEPVALTSTEYKILELLMEQPGRVFTRKKI 181 + E I +G L L + C V+ DGE V L + E+KILE+LM GRVFT+K+I Sbjct: 122 SG------ENELIKIGNLELSKEGCTVKKDGEIVTLNAKEFKILEMLMSNIGRVFTKKQI 175 Query: 182 YEAVWEDFYVYEDNSIMVHISNIRDKIERDSKKPEYLKTIRGLGYKIE 229 YE VW++ Y+ +DN+IMVHIS++RDKIE D K P +KTIRG+GY+ E Sbjct: 176 YENVWQEEYLGDDNTIMVHISHLRDKIEEDPKNPCKIKTIRGIGYRFE 223 >pir||I40084 gtcR protein - Bacillus brevis emb|CAA55264.1| gtcR [Brevibacillus brevis] Length = 242 Score = 228 bits (581), Expect = 9e-59, Method: Compositional matrix adjust. Identities = 113/230 (49%), Positives = 159/230 (69%), Gaps = 2/230 (0%) Query: 3 TILIADDELEIVELLQLYLEKE-YNILQAQNGNEALKLMQSHTVDLAILDIMMPGMDGLQ 61 TILIADDE EI+ELL+L+LE+E Y I++A +G +A ++ H VDLAI+DIMMP +DG Q Sbjct: 4 TILIADDEPEIIELLKLFLERESYRIIEAYDGEQAWNYIRQHPVDLAIIDIMMPALDGFQ 63 Query: 62 LLKRIRENDHFPVLFLSAKSQYHDKILGLELGADDYISKPFNPLEIVARVGSMLRRVHEF 121 L+KR+ PV+ LSAK++ DKILGL LGADD+ISKPFNPLE VAR+ + LRR EF Sbjct: 64 LIKRLTNEYKLPVIILSAKNRDSDKILGLGLGADDFISKPFNPLEAVARIQAQLRRAFEF 123 Query: 122 DAPAVQEKKKEQIVLGRLLLDRSSCQVEVDGEPVALTSTEYKILELLME-QPGRVFTRKK 180 + P + + +GRL L ++C V E ++T EY++L M+ +FT+++ Sbjct: 124 NEPEEKAISTQSTTVGRLTLLHTACVVYRGDETYSVTPLEYRLLNTFMQCSRTSIFTKQQ 183 Query: 181 IYEAVWEDFYVYEDNSIMVHISNIRDKIERDSKKPEYLKTIRGLGYKIEA 230 ++E W + Y +DN+IMV IS +RDKIE ++P Y+KT+RGLGYK + Sbjct: 184 LFEQAWSETYWEDDNTIMVQISRLRDKIEDQPRQPVYIKTVRGLGYKFAS 233 >ref|NP_830149.1| Two-component response regulator [Bacillus cereus ATCC 14579] gb|AAP07350.1| Two-component response regulator [Bacillus cereus ATCC 14579] Length = 233 Score = 225 bits (574), Expect = 5e-58, Method: Compositional matrix adjust. Identities = 109/231 (47%), Positives = 163/231 (70%), Gaps = 3/231 (1%) Query: 3 TILIADDELEIVELLQLYLEKE-YNILQAQNGNEALKLMQSHTVDLAILDIMMPGMDGLQ 61 TIL+ DDE EI L+ +YL+ E Y +LQA++G E L+L++ + V L +LDIMMP +DG+ Sbjct: 5 TILVVDDEKEIRNLITIYLKNEGYKVLQAEDGEEGLRLLEENEVHLVVLDIMMPKVDGIH 64 Query: 62 LLKRIRENDHFPVLFLSAKSQYHDKILGLELGADDYISKPFNPLEIVARVGSMLRRVHEF 121 + ++RE P++ LSAK+Q DKILGL GADDY++KPFNPLE++AR+ S LRR + Sbjct: 65 MCMKVREAKEMPIIMLSAKTQDMDKILGLTTGADDYVTKPFNPLELIARIKSQLRRYMKM 124 Query: 122 DAPAVQEKKKEQIVLGRLLLDRSSCQVEVDGEPVALTSTEYKILELLMEQPGRVFTRKKI 181 + A+Q ++++ +G + ++ S+ +V V+GE V LT E+ ILELL PG VF+ ++I Sbjct: 125 NGFAIQ--NEDELEIGEMKINISTHKVIVEGEEVKLTPREFSILELLARNPGMVFSAEQI 182 Query: 182 YEAVWEDFYVYEDNSIMVHISNIRDKIERDSKKPEYLKTIRGLGYKIEAPV 232 YE VW + DN++MVHI +R+KIE + +KP Y+KT+ G+GYKIE + Sbjct: 183 YEKVWNERSFQSDNTVMVHIRKVREKIEENPRKPRYIKTVWGVGYKIEKDI 233 >ref|NP_842823.1| DNA-binding response regulator [Bacillus anthracis str. Ames] gb|AAP24309.1| DNA-binding response regulator [Bacillus anthracis str. Ames] Length = 233 Score = 225 bits (573), Expect = 7e-58, Method: Compositional matrix adjust. Identities = 110/231 (47%), Positives = 162/231 (70%), Gaps = 3/231 (1%) Query: 3 TILIADDELEIVELLQLYLEKE-YNILQAQNGNEALKLMQSHTVDLAILDIMMPGMDGLQ 61 TIL+ DDE EI L+ +YL+ E Y +LQA +G E L+L++ + V L +LDIMMP +DG+ Sbjct: 5 TILVVDDEKEIRNLITIYLKNEGYKVLQAGDGEEGLRLLEENEVHLVVLDIMMPKVDGIH 64 Query: 62 LLKRIRENDHFPVLFLSAKSQYHDKILGLELGADDYISKPFNPLEIVARVGSMLRRVHEF 121 + +IRE P++ LSAK+Q DKILGL GADDY++KPFNPLE++AR+ S LRR + Sbjct: 65 MCMKIREEKEMPIIMLSAKTQDMDKILGLTTGADDYVTKPFNPLELIARIKSQLRRYMKM 124 Query: 122 DAPAVQEKKKEQIVLGRLLLDRSSCQVEVDGEPVALTSTEYKILELLMEQPGRVFTRKKI 181 + A+Q ++++ +G + ++ S+ +V V+GE V LT E+ ILELL PG VF+ ++I Sbjct: 125 NGFAIQ--NEDELEIGEMKINISTHKVIVEGEEVKLTPREFSILELLARNPGMVFSAEQI 182 Query: 182 YEAVWEDFYVYEDNSIMVHISNIRDKIERDSKKPEYLKTIRGLGYKIEAPV 232 YE VW + DN++MVHI +R+KIE + +KP Y+KT+ G+GYKIE + Sbjct: 183 YEKVWNERSFQSDNTVMVHIRKVREKIEENPRKPRYIKTVWGVGYKIEKDI 233 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.139 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 343,324,356 Number of extensions: 13940516 Number of successful extensions: 54594 Number of sequences better than 1.0e-05: 5493 Number of HSP's gapped: 49263 Number of HSP's successfully gapped: 5537 Length of query: 234 Length of database: 757,237,578 Length adjustment: 122 Effective length of query: 112 Effective length of database: 425,995,500 Effective search space: 47711496000 Effective search space used: 47711496000 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 124 (52.4 bits)