BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0515.0006.p (322 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_691381.1| ornithine carbamoyltransferase [Oceanobacillus ... 418 e-116 ref|NP_142671.1| ornithine carbamoyltransferase [Pyrococcus hori... 403 e-111 ref|NP_126998.1| ornithine carbamoyltransferase [Pyrococcus abys... 403 e-111 ref|NP_243760.1| ornithine carbamoyltransferase [Bacillus halodu... 402 e-111 ref|ZP_00061434.1| COG0078: Ornithine carbamoyltransferase [Clos... 402 e-111 >ref|NP_691381.1| ornithine carbamoyltransferase [Oceanobacillus iheyensis HTE831] sp|Q8ET05|OTC_OCEIH Ornithine carbamoyltransferase (OTCase) dbj|BAC12416.1| ornithine carbamoyltransferase [Oceanobacillus iheyensis HTE831] Length = 322 Score = 418 bits (1075), Expect = e-116, Method: Compositional matrix adjust. Identities = 201/308 (65%), Positives = 246/308 (79%) Query: 14 QQLKGRDLLELNDYSPEEITYLIDLAIELKRKQKSGEVYQPLKGKTIGLIFEKSSTRTRV 73 Q+LKGRD L L DY+ +EI YLIDLA LK++ K G +++PLKGKT+G+IFEKSSTRTRV Sbjct: 13 QELKGRDFLTLADYTKDEINYLIDLADYLKKQHKDGVIFEPLKGKTLGMIFEKSSTRTRV 72 Query: 74 SFEVGMYQLGGHALFLSKNDIQLGRGETVGDTAQVMSRYLDGIMIRTFGHDKVEDLARYA 133 SFE G+YQLGG +FLS DIQ+GRGET+ DTA+V+S YLDGIMIRTF + VE+LA++A Sbjct: 73 SFETGIYQLGGLGIFLSSKDIQIGRGETIADTAKVLSGYLDGIMIRTFAQEDVEELAKHA 132 Query: 134 SVPVINGLSDLAHPCQVLADYQTVYEHKGKLKGLKLAYIGDGNNMAHSLLIGGAKLGVHV 193 S+PVINGL+DL HPCQVLAD QT+ E KGKL G+KL YIGDGNNM HSL++G AK G+H+ Sbjct: 133 SIPVINGLTDLYHPCQVLADLQTIKEVKGKLHGVKLVYIGDGNNMTHSLMLGAAKTGMHM 192 Query: 194 SVAGPEGYEPDAAVVAEAREIAKETGALIVVTRSPQEAVQDADVIYTDVWASMGFEAEQL 253 P+GY P+ V+ +A+ IA + GA+I T AVQ+ADVIYTDVWASMG E EQ Sbjct: 193 VAVTPDGYTPNKEVLTKAKSIANQHGAIIEWTSDIATAVQEADVIYTDVWASMGQEEEQQ 252 Query: 254 AREAAFKDYQVNEELVKGAKSDYLFLHCLPAHREEEVSTGVIDGPNSVIFDQAENRLHAQ 313 RE F++YQVNE L++ AK+D +F+HCLPAHR EEV+ GVIDG SV+F QAENRLHAQ Sbjct: 253 QREKDFENYQVNESLLEKAKTDVIFMHCLPAHRGEEVTAGVIDGKQSVVFQQAENRLHAQ 312 Query: 314 KALMAALM 321 KALM ALM Sbjct: 313 KALMTALM 320 >ref|NP_142671.1| ornithine carbamoyltransferase [Pyrococcus horikoshii] sp|O58457|OTC_PYRHO Ornithine carbamoyltransferase (OTCase) pir||G71119 probable ornithine carbamoyltransferase - Pyrococcus horikoshii dbj|BAA29817.1| 317aa long hypothetical ornithine carbamoyltransferase [Pyrococcus horikoshii] Length = 317 Score = 403 bits (1036), Expect = e-111, Method: Compositional matrix adjust. Identities = 189/307 (61%), Positives = 237/307 (77%) Query: 16 LKGRDLLELNDYSPEEITYLIDLAIELKRKQKSGEVYQPLKGKTIGLIFEKSSTRTRVSF 75 LKGRDLL L DY+PEEI +++ A K QK G+ ++ L+GKT+ +IF+K STRTRVSF Sbjct: 5 LKGRDLLCLQDYTPEEIWTILETAKMFKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSF 64 Query: 76 EVGMYQLGGHALFLSKNDIQLGRGETVGDTAQVMSRYLDGIMIRTFGHDKVEDLARYASV 135 EV M LGGHAL+L+ D+QL RGET+ DTA+V+SRY+D IM R + H VEDLA+YASV Sbjct: 65 EVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYAHKDVEDLAKYASV 124 Query: 136 PVINGLSDLAHPCQVLADYQTVYEHKGKLKGLKLAYIGDGNNMAHSLLIGGAKLGVHVSV 195 PVINGLSD +HPCQ LADY T++E KG +KG+K+ Y+GDGNN+ HSL+I G KLG V V Sbjct: 125 PVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVCHSLMIAGTKLGADVVV 184 Query: 196 AGPEGYEPDAAVVAEAREIAKETGALIVVTRSPQEAVQDADVIYTDVWASMGFEAEQLAR 255 A PEGYEPD V+ A + A E+G + P +AV+DADVIYTDVWASMG EAE R Sbjct: 185 ATPEGYEPDKKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEER 244 Query: 256 EAAFKDYQVNEELVKGAKSDYLFLHCLPAHREEEVSTGVIDGPNSVIFDQAENRLHAQKA 315 F+ +QVN++LVK AKSDY+F+HCLPAHR EEV+ VID PNSV++D+AENRLHAQKA Sbjct: 245 RKIFRPFQVNKDLVKHAKSDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKA 304 Query: 316 LMAALMG 322 ++A L+G Sbjct: 305 VLALLLG 311 >ref|NP_126998.1| ornithine carbamoyltransferase [Pyrococcus abyssi] sp|O93656|OTC_PYRAB Ornithine carbamoyltransferase (OTCase) pir||G75041 ornithine carbamoyltransferase (argf) PAB1502 - Pyrococcus abyssi (strain Orsay) emb|CAB50228.1| argF ornithine carbamoyltransferase [Pyrococcus abyssi] Length = 317 Score = 403 bits (1036), Expect = e-111, Method: Compositional matrix adjust. Identities = 190/307 (61%), Positives = 238/307 (77%) Query: 16 LKGRDLLELNDYSPEEITYLIDLAIELKRKQKSGEVYQPLKGKTIGLIFEKSSTRTRVSF 75 LKGRDLL L DY+PEEI +++ A LK QK G+ ++ L+GKT+ +IF+K STRTRVSF Sbjct: 5 LKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSF 64 Query: 76 EVGMYQLGGHALFLSKNDIQLGRGETVGDTAQVMSRYLDGIMIRTFGHDKVEDLARYASV 135 EV M LGGHAL+L+ D+QL RGET+ DTA+V+SRY+D IM R + H VEDLA+YASV Sbjct: 65 EVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASV 124 Query: 136 PVINGLSDLAHPCQVLADYQTVYEHKGKLKGLKLAYIGDGNNMAHSLLIGGAKLGVHVSV 195 PVINGLSD +HPCQ LADY T++E KG +KG+K+ Y+GDGNN+AHSL+I G KLG V V Sbjct: 125 PVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVV 184 Query: 196 AGPEGYEPDAAVVAEAREIAKETGALIVVTRSPQEAVQDADVIYTDVWASMGFEAEQLAR 255 A PEGYEPD V+ A + A E+G + P +AV+DADVIYTDVWASMG EAE R Sbjct: 185 ATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEER 244 Query: 256 EAAFKDYQVNEELVKGAKSDYLFLHCLPAHREEEVSTGVIDGPNSVIFDQAENRLHAQKA 315 F+ +QVN++LVK AK DY+F+HCLPAHR EEV+ VID PNSV++D+AENRLHAQKA Sbjct: 245 RKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKA 304 Query: 316 LMAALMG 322 ++A L+G Sbjct: 305 VLALLLG 311 >ref|NP_243760.1| ornithine carbamoyltransferase [Bacillus halodurans] sp|Q9K8V8|OTC_BACHD Ornithine carbamoyltransferase (OTCase) pir||F84011 ornithine carbamoyltransferase argf [imported] - Bacillus halodurans (strain C-125) dbj|BAB06613.1| ornithine carbamoyltransferase [Bacillus halodurans] Length = 319 Score = 402 bits (1033), Expect = e-111, Method: Compositional matrix adjust. Identities = 195/306 (63%), Positives = 235/306 (76%) Query: 16 LKGRDLLELNDYSPEEITYLIDLAIELKRKQKSGEVYQPLKGKTIGLIFEKSSTRTRVSF 75 LKGRDLL L DY+PEE+ L+ A+ELK+K K+GE L GK++G+IFE +STRTRVSF Sbjct: 11 LKGRDLLTLLDYTPEEVQQLLTQALELKQKAKNGEPTPYLTGKSLGMIFENASTRTRVSF 70 Query: 76 EVGMYQLGGHALFLSKNDIQLGRGETVGDTAQVMSRYLDGIMIRTFGHDKVEDLARYASV 135 EVGM QLGGHALFLS D+Q+GRGE + DTA V+SRY+D IMIRT H+ VE+LA YA+V Sbjct: 71 EVGMTQLGGHALFLSPKDLQIGRGEPIKDTANVLSRYVDAIMIRTNSHESVEELAHYATV 130 Query: 136 PVINGLSDLAHPCQVLADYQTVYEHKGKLKGLKLAYIGDGNNMAHSLLIGGAKLGVHVSV 195 PVIN L+D HPCQ LAD T+ E K L G KLAYIGDGNN+ HSLL GAK G+ V+V Sbjct: 131 PVINALTDAYHPCQALADALTILEKKETLIGKKLAYIGDGNNVCHSLLAIGAKTGMDVTV 190 Query: 196 AGPEGYEPDAAVVAEAREIAKETGALIVVTRSPQEAVQDADVIYTDVWASMGFEAEQLAR 255 A P+GYE D + A E AKETGA +V T +PQ A ++AD IYTDVWASMG+EAEQ R Sbjct: 191 ATPKGYEVDQEIFQRATEAAKETGATLVQTTNPQVAAENADAIYTDVWASMGYEAEQSER 250 Query: 256 EAAFKDYQVNEELVKGAKSDYLFLHCLPAHREEEVSTGVIDGPNSVIFDQAENRLHAQKA 315 E F+ YQVN++L+ AK D FLHCLPAHR EEV+ VIDGP+S I+DQAENRLHAQKA Sbjct: 251 EEVFQPYQVNDQLLTLAKKDVSFLHCLPAHRGEEVTASVIDGPHSAIYDQAENRLHAQKA 310 Query: 316 LMAALM 321 ++ AL+ Sbjct: 311 VLTALL 316 >ref|ZP_00061434.1| COG0078: Ornithine carbamoyltransferase [Clostridium thermocellum ATCC 27405] Length = 307 Score = 402 bits (1032), Expect = e-111, Method: Compositional matrix adjust. Identities = 194/302 (64%), Positives = 237/302 (78%) Query: 21 LLELNDYSPEEITYLIDLAIELKRKQKSGEVYQPLKGKTIGLIFEKSSTRTRVSFEVGMY 80 L+ L+D + E+ + LA +LKR+QK G + LKGKT+G+IF KSSTRTRVSFEVGMY Sbjct: 4 LISLHDLTVEDFESIFKLAEKLKRQQKEGIPHHLLKGKTLGMIFTKSSTRTRVSFEVGMY 63 Query: 81 QLGGHALFLSKNDIQLGRGETVGDTAQVMSRYLDGIMIRTFGHDKVEDLARYASVPVING 140 QLGG+ LFLS NDIQLGRGET+ DTAQV+SRY+DGIMIRTF VEDLARY +VPVING Sbjct: 64 QLGGYPLFLSANDIQLGRGETIYDTAQVLSRYVDGIMIRTFAQSDVEDLARYGNVPVING 123 Query: 141 LSDLAHPCQVLADYQTVYEHKGKLKGLKLAYIGDGNNMAHSLLIGGAKLGVHVSVAGPEG 200 L+DL HPCQ+LAD T+YEHKG LKGLKLAY+GDGNN+A+SLL G AK+G+ ++VA P+G Sbjct: 124 LTDLMHPCQILADLFTIYEHKGTLKGLKLAYVGDGNNVANSLLHGCAKVGMDIAVASPKG 183 Query: 201 YEPDAAVVAEAREIAKETGALIVVTRSPQEAVQDADVIYTDVWASMGFEAEQLAREAAFK 260 YE D+ +V EA+E AK +GA I++T P+EA++DADV+YTD W SMG E+E+ R F Sbjct: 184 YECDSRIVEEAKEDAKASGANILLTEDPEEAIKDADVVYTDTWVSMGQESEKEERIKVFM 243 Query: 261 DYQVNEELVKGAKSDYLFLHCLPAHREEEVSTGVIDGPNSVIFDQAENRLHAQKALMAAL 320 YQVN L A D +FLHCLPA+R EV+ VIDG SVIFD+AENRLH QKA+MA L Sbjct: 244 PYQVNNTLFSKAHEDAIFLHCLPAYRGYEVTEDVIDGSQSVIFDEAENRLHVQKAIMALL 303 Query: 321 MG 322 MG Sbjct: 304 MG 305 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.316 0.134 0.374 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 454,558,990 Number of extensions: 18652047 Number of successful extensions: 50818 Number of sequences better than 1.0e-05: 1439 Number of HSP's gapped: 48466 Number of HSP's successfully gapped: 1439 Length of query: 322 Length of database: 757,237,578 Length adjustment: 126 Effective length of query: 196 Effective length of database: 415,135,104 Effective search space: 81366480384 Effective search space used: 81366480384 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 126 (53.1 bits)