BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0514.0011.p (296 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gb|AAO43656.1| dihydrodipicolinate synthase [Escherichia coli] 226 3e-58 gb|EAH05399.1| unknown [environmental sequence] 198 1e-49 ref|NP_752691.1| Putative dihydrodipicolinate synthase [Escheric... 196 5e-49 gb|EAG15079.1| unknown [environmental sequence] 191 2e-47 ref|NP_614890.1| Dihydrodipicolinate synthase/N-acetylneuraminat... 188 2e-46 >gb|AAO43656.1| dihydrodipicolinate synthase [Escherichia coli] Length = 294 Score = 226 bits (577), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 114/293 (38%), Positives = 175/293 (59%), Gaps = 5/293 (1%) Query: 1 MLEVKGIIPAMVTPLDQREEIDEKALRQMVNRYIDAGVHGLFCLGTNGEFFNLSFEEKLT 60 M E+KGII AMVTP D+ E++D A ++M +D GVHGLF GTNGEF LS +EK+ Sbjct: 1 MKELKGIITAMVTPFDETEKMDITAAKKMARWLVDNGVHGLFICGTNGEFHLLSDDEKVE 60 Query: 61 VAQIVIHEARGRVPVYAGAGCAGTGETRRLAQRLEQAGADALSVITPYFLTYTQPELQYH 120 + + V+ E V + AGAGC T +T L +RL AGAD +SV+TPY+L Q +L H Sbjct: 61 LTKAVVEEVGNEVTICAGAGCCSTKQTIELTKRLVDAGADYISVVTPYYLVPNQEDLYRH 120 Query: 121 FEAVAGETSLPLVLYTIPARTGNTLSVQTVAKLAELPNVVGIKDSSGSFD---NILQLID 177 + +A T+ P++LY +P +TG ++ +T +LA++ N+V IKDSSG F+ L++ Sbjct: 121 YYDIAFSTTAPIILYNLPGQTGLSIEYETANRLADIKNIVAIKDSSGKFEVQKQYLEIAK 180 Query: 178 HTPESFSVLAGTDSLILSTLMXXXXXXXXXXXNIFPSTVVAIYEHWQCGEYEQAEQAQRV 237 H ++F VL G+DSL+L N+ P+ V +Y ++ GE E+A++ + Sbjct: 181 H--KNFKVLNGSDSLMLDAFKEGSVAAVAATSNVLPTIEVDLYNYFMAGEMEKAQEERNK 238 Query: 238 LRDLRAAFALGTLPSVLKAVLDEIGLPAGPARRPVAPLTPQALEEVRRMVAGY 290 + LR T P+V+K L+ +G+ AG RRP+ +E+++ M+ GY Sbjct: 239 MDALRMTIKKMTAPAVMKEALNLMGVKAGITRRPIHMPNDAIVEDIKEMLKGY 291 >gb|EAH05399.1| unknown [environmental sequence] Length = 181 Score = 198 bits (504), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 96/173 (55%), Positives = 123/173 (71%) Query: 5 KGIIPAMVTPLDQREEIDEKALRQMVNRYIDAGVHGLFCLGTNGEFFNLSFEEKLTVAQI 64 KGIIPA++TP+ EE+DE LR ++ R I+AGVH LF LGTNGEF L+ EKL +A I Sbjct: 6 KGIIPALITPMTASEEVDEAGLRALIERLIEAGVHALFVLGTNGEFIALNEAEKLRIATI 65 Query: 65 VIHEARGRVPVYAGAGCAGTGETRRLAQRLEQAGADALSVITPYFLTYTQPELQYHFEAV 124 + +AR RVPV AG G T + L ++ G DA+SVITPYF TQPEL H+E + Sbjct: 66 AVDQARSRVPVIAGTGAYATRDVIDLNSKMLDVGVDAVSVITPYFNGATQPELFTHYERI 125 Query: 125 AGETSLPLVLYTIPARTGNTLSVQTVAKLAELPNVVGIKDSSGSFDNILQLID 177 A T+LP++LYTIPA+ G TL+V TV +LAE+PN+ GIKDS G FD +LQLI+ Sbjct: 126 ARATTLPVMLYTIPAKAGITLTVDTVRRLAEIPNIRGIKDSGGDFDRLLQLIN 178 >ref|NP_752691.1| Putative dihydrodipicolinate synthase [Escherichia coli CFT073] gb|AAN79234.1| Putative dihydrodipicolinate synthase [Escherichia coli CFT073] Length = 295 Score = 196 bits (498), Expect = 5e-49, Method: Compositional matrix adjust. Identities = 111/290 (38%), Positives = 168/290 (57%), Gaps = 5/290 (1%) Query: 4 VKGIIPAMVTPLDQREEIDEKALRQMVNRYIDAGVHGLFCLGTNGEFFNLSFEEKLTVAQ 63 ++G++ A+VTP ++ AL+ VNR ++AG + +FC GTNGEFF L+ +EKL+V Q Sbjct: 5 IEGVLTAIVTPFTATGSLNIPALKVQVNRQLEAG-NAIFCGGTNGEFFVLNEQEKLSVTQ 63 Query: 64 IVIHEARGRVPVYAGAGCAGTGETRRLAQRLEQAGADALSVITPYFLTYTQPELQYHFEA 123 + E GR PV A G T ET RL Q++E+ G DA+SVI PYF+ Q EL H+ A Sbjct: 64 TCVDEVAGRAPVVAHIGEISTRETIRLGQQIEKLGVDAVSVIAPYFVPLKQEELIAHYSA 123 Query: 124 VAGETSLPLVLYTIPARTGNTLSVQTVAKLAELPNVVGIKDSSGSFDNILQLID--HTPE 181 +A S+P+ LY IPARTGNT+ +T LA PN++GIKDS+GS +++ +D + Sbjct: 124 IADALSIPMFLYNIPARTGNTIQPETARALASHPNIIGIKDSAGSDESLKGFLDAVRDID 183 Query: 182 SFSVLAGTDSLILSTLMXXXXXXXXXXXNIFPSTVVAIYEHWQCGEYEQAEQAQRVLRDL 241 F+VL G DSLI + NI P + AI+ + G+ E + +AQ + L Sbjct: 184 GFNVLNGPDSLIHKGFVEGCSTCISGLANIAPREINAIWSRFHAGDIEGSYEAQESVTGL 243 Query: 242 RAA-FALGTLPSVLKAVLDEIGLPAGPARRPVAPLTPQALEEVRRMVAGY 290 R + + P+ +K L +G G +R V TP+ + E+++++ Y Sbjct: 244 RTDLYKVAFSPAAVKKALQLMGHDVGDSRYAVN-FTPEQISEIQQIIRHY 292 >gb|EAG15079.1| unknown [environmental sequence] Length = 279 Score = 191 bits (484), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 109/269 (40%), Positives = 159/269 (59%), Gaps = 5/269 (1%) Query: 25 ALRQMVNRYIDAGVHGLFCLGTNGEFFNLSFEEKLTVAQIVIHEARGRVPVYAGAGCAGT 84 ALRQ V+ I AG +G+FC GTNGEFF L+ EEK+ VA+ + EA GRVPV A G T Sbjct: 11 ALRQQVHCQIAAG-NGIFCGGTNGEFFVLNEEEKIAVARTCVEEAAGRVPVVAHIGEIST 69 Query: 85 GETRRLAQRLEQAGADALSVITPYFLTYTQPELQYHFEAVAGETSLPLVLYTIPARTGNT 144 ETRRL Q++ + G DA+S ITP+F+ Q EL H+ A+A S+PL LY IPARTGNT Sbjct: 70 RETRRLGQQIARLGVDAVSAITPWFVPLKQEELINHYTAIADALSVPLFLYNIPARTGNT 129 Query: 145 LSVQTVAKLAELPNVVGIKDSSGSFDNILQLID--HTPESFSVLAGTDSLILSTLMXXXX 202 ++ +T +LA N+VGIKDS+GS++++ +D + F VL G DSLI + Sbjct: 130 IAPETARQLARHENIVGIKDSAGSYESLKGFLDAVRDIDGFDVLNGPDSLIHQGFVDGCS 189 Query: 203 XXXXXXXNIFPSTVVAIYEHWQCGEYEQAEQAQRVLRDLRAA-FALGTLPSVLKAVLDEI 261 N+ P+ + AI+ H+ G+ + QAQ + LR + + P+ +K L + Sbjct: 190 ACISGLANVAPAEINAIWSHFHAGDIAGSRQAQERVTGLRTDLYKVAFSPAAVKKALQLM 249 Query: 262 GLPAGPARRPVAPLTPQALEEVRRMVAGY 290 G G +R V + Q L++++ ++ Y Sbjct: 250 GHEVGDSRYAV-QFSDQQLQQIKNIINTY 277 >ref|NP_614890.1| Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Methanopyrus kandleri AV19] sp|Q8TUZ4|DAPA_METKA Dihydrodipicolinate synthase (DHDPS) gb|AAM02820.1| Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Methanopyrus kandleri AV19] Length = 300 Score = 188 bits (477), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 105/286 (36%), Positives = 158/286 (55%), Gaps = 2/286 (0%) Query: 2 LEVKGIIPAMVTPL-DQREEIDEKALRQMVNRYIDAGVHGLFCLGTNGEFFNLSFEEKLT 60 +++G+IPA++TP D + I+E+ LR+ V+R ++AGVHG+ GT GE LS E Sbjct: 3 FQIEGVIPALITPFTDDLKGINEEGLRENVSRLLEAGVHGVVPAGTTGESSTLSHAEHRR 62 Query: 61 VAQIVIHEARGRVPVYAGAGCAGTGETRRLAQRLEQAGADALSVITPYFLTYTQPELQYH 120 V +IV+ E G+VPV AGAG T E L+ E GADA+ + PY+ Q L H Sbjct: 63 VIEIVVDEVNGKVPVIAGAGSNSTREALELSTYAEDVGADAILSVVPYYNKPPQEGLFIH 122 Query: 121 FEAVAGETSLPLVLYTIPARTGNTLSVQTVAKLA-ELPNVVGIKDSSGSFDNILQLIDHT 179 F +A P++LY +P+RTG L +T AKLA E ++VG+K++SG D + + I+ T Sbjct: 123 FSKIAEAVECPIILYNVPSRTGCALEPETAAKLAEEYSHIVGVKEASGDLDVVQRFIEET 182 Query: 180 PESFSVLAGTDSLILSTLMXXXXXXXXXXXNIFPSTVVAIYEHWQCGEYEQAEQAQRVLR 239 P+ F +L+G D L L L N+ P +V +YE W+ G+ E+A + L Sbjct: 183 PDDFILLSGVDELTLPILAVGGVGVISVTANVAPELMVEMYEAWKSGDVERARELHYELL 242 Query: 240 DLRAAFALGTLPSVLKAVLDEIGLPAGPARRPVAPLTPQALEEVRR 285 L A T P +KA ++ +G+ + P R P+ E +RR Sbjct: 243 PLHRALFTETNPIPVKAAVELVGMASSPPRPPLKEAREDTKELLRR 288 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.320 0.136 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 403,645,324 Number of extensions: 15756319 Number of successful extensions: 43798 Number of sequences better than 1.0e-05: 1002 Number of HSP's gapped: 43191 Number of HSP's successfully gapped: 1002 Length of query: 296 Length of database: 757,237,578 Length adjustment: 125 Effective length of query: 171 Effective length of database: 417,850,203 Effective search space: 71452384713 Effective search space used: 71452384713 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 125 (52.8 bits)