BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0510.0004.p (192 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_721208.1| conserved hypothetical protein [Streptococcus m... 64 1e-09 ref|NP_823542.1| putative hydroxylase [Streptomyces avermitilis ... 64 2e-09 gb|EAA61485.1| hypothetical protein AN9194.2 [Aspergillus nidula... 59 5e-08 gb|AAC18114.1| FrnS [Streptomyces roseofulvus] 59 5e-08 emb|CAA07626.1| hypothetical protein [Streptomyces coelicolor A3... 57 2e-07 >ref|NP_721208.1| conserved hypothetical protein [Streptococcus mutans UA159] gb|AAN58514.1| conserved hypothetical protein [Streptococcus mutans UA159] Length = 277 Score = 64.3 bits (155), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 44/137 (32%), Positives = 74/137 (54%), Gaps = 6/137 (4%) Query: 35 LQAAKTNGVQNIVFLSSASINRSDSDHNDNAKKHKEVEDQIKAFGFNYAFIRAEAFMHNA 94 L AA GV++IV+ S N + A+ H + E IK GF Y F+R ++ Sbjct: 84 LDAAHEAGVKHIVYTSF--YNAATEATFTLARDHAKTEKYIKERGFTYTFLRDNFYLD-- 139 Query: 95 IYWRDLFRYNKGTIKLPALDAKLASVHETDIAEVISIVLTGFNKFSGQVLTLTGANILSQ 154 ++ DL N G I+ PA + K+++V D++EV + +L +K+ Q+L +TG LS Sbjct: 140 -FFLDLC-LNNGEIRGPAGNGKVSAVARQDVSEVATTILAKPDKWKNQLLNMTGPADLSM 197 Query: 155 LNILSEISKQLGQQIGF 171 +I+ +S+Q G+ I + Sbjct: 198 ADIVHFVSEQKGEIIPY 214 >ref|NP_823542.1| putative hydroxylase [Streptomyces avermitilis MA-4680] dbj|BAB69245.1| putative hydroxylase [Streptomyces avermitilis] dbj|BAC70077.1| putative hydroxylase [Streptomyces avermitilis MA-4680] Length = 221 Score = 63.9 bits (154), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 46/138 (33%), Positives = 73/138 (52%), Gaps = 1/138 (0%) Query: 35 LQAAKTNGVQNIVFLSSASINRSDSDHNDNAKKHKEVEDQIKAFGFNYAFIRAEAFMHNA 94 + AA++ GV+ +V LSS S+ + S+ N A+ H+ VE I+ G ++ FIR F NA Sbjct: 21 VAAAQSAGVRQVVLLSSVSVVMATSEQNPIARMHRTVELAIERSGLDWTFIRPGMFATNA 80 Query: 95 IYWRDLFRYNKGTIKLPALDAKLASVHETDIAEVISIVLTGFNKFSGQVLTLTGANILSQ 154 +W +G ++LP +A+ A VHE D+A + LT S Q T+ G+ L+ Sbjct: 81 RWWWGESIRGEGVVRLPYPEAQNAPVHEKDMAALAVTALTE-PGHSHQAYTVHGSESLTL 139 Query: 155 LNILSEISKQLGQQIGFE 172 + I + LG+ I E Sbjct: 140 RRQVEHIGEALGRPIRVE 157 >gb|EAA61485.1| hypothetical protein AN9194.2 [Aspergillus nidulans FGSC A4] Length = 332 Score = 59.3 bits (142), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 46/161 (28%), Positives = 79/161 (49%), Gaps = 26/161 (16%) Query: 33 EILQAAKTNGVQNIVFLSSASINRSDSDHNDNAKKHKEVE--------DQIKAFGFNYAF 84 E+++A K G+ N+ FLSSA + ++ D N ++ ++E D + G + Sbjct: 96 ELIEATKQAGIPNVCFLSSAGCDLAERDKQPNLRQFIDLEALFMASKGDASTSTGHSPVV 155 Query: 85 IRAEAFMHNAIYWRDLFRYNK-----GTIKLP-ALDAKLASVHETDIAEVISIVLTGFNK 138 IR Y +L Y+K G + LP + K A + D+++V++ VLTG K Sbjct: 156 IRP------GFYAENLLIYSKQAQEQGKLPLPVGKNNKFAPIALGDVSQVVAHVLTGEGK 209 Query: 139 --FS----GQVLTLTGANILSQLNILSEISKQLGQQIGFEE 173 FS GQ++ LTG + + + + S LGQ++ FE+ Sbjct: 210 HGFSDQHRGQLMVLTGPMLTTGDELATAASNALGQELKFED 250 >gb|AAC18114.1| FrnS [Streptomyces roseofulvus] Length = 305 Score = 59.3 bits (142), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 32/134 (23%), Positives = 66/134 (49%), Gaps = 3/134 (2%) Query: 41 NGVQNIVFLSSASINRSDSDHNDNAKKHKEVEDQIKAFGFNYAFIRAEAFMHNAIYWRDL 100 G++ +V LS+ + + D N +KH E ++ G + F+R AF A+ W Sbjct: 102 RGLREVVVLSATAAAHPEYD-NPMFQKHVRGERHVRGSGVPWVFLRPGAFASLALLWAPA 160 Query: 101 FRYNKGTIKLPALDAKLASVHETDIAEVISIVLTG-FNKFSGQVLTLTGANILSQLNILS 159 + G +++P + + DIA+V + VLT +++G+ + L+G +L+ + Sbjct: 161 L-HGDGVVRVPHAGLAVPLIDPRDIADVAAAVLTAPVERWAGKAVPLSGPEVLTLPGRTA 219 Query: 160 EISKQLGQQIGFEE 173 ++ +LG+ + E Sbjct: 220 VLAAELGRPLRVEP 233 >emb|CAA07626.1| hypothetical protein [Streptomyces coelicolor A3(2)] Length = 284 Score = 57.4 bits (137), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 36/132 (27%), Positives = 66/132 (50%), Gaps = 3/132 (2%) Query: 42 GVQNIVFLSSASINRSDSDHNDNAKKHKEVEDQIKAFGFNYAFIRAEAFMHNAIYWRDLF 101 GV+++V LS ++ +D + ++ +E E ++ G ++ F+RA FM N + W Sbjct: 88 GVRHLVKLSMLAVGEPGAD-DFITRRQRENERAVRESGLDWTFLRARTFMSNTLSWAPAI 146 Query: 102 RYNKGTIKLPALDAKLASVHETDIAEVISIVLTGFNKFSGQVLTLTGANILSQLNILSEI 161 R + G ++ + +A V DIAEV LT G+ L+G ++ + + Sbjct: 147 RSD-GVVRALYGTSPVACVDPRDIAEVAVRALT-RPGHEGRAYALSGPEAITARQQTARL 204 Query: 162 SKQLGQQIGFEE 173 S+ LG+ + FEE Sbjct: 205 SEVLGRSLRFEE 216 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.133 0.372 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 223,483,695 Number of extensions: 8443317 Number of successful extensions: 21856 Number of sequences better than 1.0e-05: 14 Number of HSP's gapped: 21898 Number of HSP's successfully gapped: 14 Length of query: 192 Length of database: 757,237,578 Length adjustment: 119 Effective length of query: 73 Effective length of database: 434,140,797 Effective search space: 31692278181 Effective search space used: 31692278181 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 122 (51.6 bits)