BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0506.0005.p (470 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_243234.1| DNA mismatch repair protein [Bacillus haloduran... 397 e-109 ref|NP_833491.1| DNA mismatch repair protein mutL [Bacillus cere... 397 e-109 ref|NP_980099.1| DNA mismatch repair protein MutL [Bacillus cere... 397 e-109 ref|NP_657734.1| DNA_mis_repair, DNA mismatch repair protein [Ba... 397 e-109 ref|NP_464929.1| DNA mismatch repair protein [Listeria monocytog... 393 e-108 >ref|NP_243234.1| DNA mismatch repair protein [Bacillus halodurans] sp|Q9KAC1|MUTL_BACHD DNA mismatch repair protein mutL pir||H83945 DNA mismatch repair protein mulT [imported] - Bacillus halodurans (strain C-125) dbj|BAB06087.1| DNA mismatch repair protein [Bacillus halodurans] Length = 637 Score = 397 bits (1020), Expect = e-109, Method: Compositional matrix adjust. Identities = 197/353 (55%), Positives = 257/353 (72%), Gaps = 3/353 (0%) Query: 2 LDEHIANQIAAGEVVERPASVVKELVENAIDAGSTRIEVSVEEGGLQSIRVKDNGSGIDP 61 LD+H++N+IAAGEVVERPASVVKELVENA+DA S +I + VE GGL IRV D+G GI+ Sbjct: 7 LDDHLSNKIAAGEVVERPASVVKELVENALDANSRKITIEVEAGGLDRIRVIDDGDGIER 66 Query: 62 EDCETAFYRHATSKIVNGRDLFQITSLGFRGEALPSIASVSKLSLLTSSNEDGKGRALDI 121 ED ETAF+RHATSKI +DLFQI +LGFRGEALPSIASVS + + TS+ DG G + + Sbjct: 67 EDVETAFFRHATSKIKTDKDLFQIATLGFRGEALPSIASVSHVQIKTSTGGDG-GTEMVL 125 Query: 122 EGGKLIRNEDEPAGKGSDLAVRELFYNTPARLKYMKSVQTELGHISDTMYRVALAHPSIS 181 EGG + + GKG+DL V +LFYNTPARLKY+K+V TELG+ISD + R+ALAHP +S Sbjct: 126 EGGVIKKIGSTAMGKGTDLTVTQLFYNTPARLKYVKTVHTELGNISDVVNRLALAHPYVS 185 Query: 182 FTLHHNGNQLLHTLGNGDLLQVIAAVYGTSAAKAMLPLAAEDPDYRISGYVSRPEWTRSN 241 F L HNG +L T GNGD LQVIAA+YG + AK M+PL+ E D+ +SG+ ++PE TR++ Sbjct: 186 FQLFHNGKNVLRTSGNGDQLQVIAAIYGRTVAKQMVPLSGETIDFTVSGFAAKPEVTRAS 245 Query: 242 RNAVTTIVGGRYIRSNGLNAAIMRAYHTLLPINRYPLLVLQLEMHPSLVDVNVHPAKLEV 301 R ++ +V GRYIR+ L+ AI + +HTLLPI RYP+ ++ +E+ P L+DVNVHP+KLEV Sbjct: 246 RQYMSLLVNGRYIRNVALSKAIQQGFHTLLPIGRYPIAIVNIELDPQLIDVNVHPSKLEV 305 Query: 302 RFSKEAELYAFVEQEIRKVLMGQSLIPRPSKEIIGAKGSS--SFIQEQFAFSK 352 R SKE EL V + I + + LIP +K G + S SF + F +K Sbjct: 306 RVSKEEELCRLVTETIERAFKKEQLIPEATKPTGGKQKSEQLSFTLDDFTSAK 358 >ref|NP_833491.1| DNA mismatch repair protein mutL [Bacillus cereus ATCC 14579] gb|AAP10692.1| DNA mismatch repair protein mutL [Bacillus cereus ATCC 14579] Length = 647 Score = 397 bits (1020), Expect = e-109, Method: Compositional matrix adjust. Identities = 197/357 (55%), Positives = 253/357 (70%), Gaps = 2/357 (0%) Query: 2 LDEHIANQIAAGEVVERPASVVKELVENAIDAGSTRIEVSVEEGGLQSIRVKDNGSGIDP 61 LD+ ++N IAAGEVVERPASVVKELVEN+IDA ST IE+ +EE GL IR+ DNG GI Sbjct: 7 LDDQLSNLIAAGEVVERPASVVKELVENSIDANSTSIEIHLEEAGLSKIRIIDNGDGIAE 66 Query: 62 EDCETAFYRHATSKIVNGRDLFQITSLGFRGEALPSIASVSKLSLLTSSNEDGKGRALDI 121 EDC AF RHATSKI + DLF+I +LGFRGEALPSIASVS+L L+TS+ D G L I Sbjct: 67 EDCIVAFERHATSKIKDENDLFRIRTLGFRGEALPSIASVSELELITSTG-DAPGTHLII 125 Query: 122 EGGKLIRNEDEPAGKGSDLAVRELFYNTPARLKYMKSVQTELGHISDTMYRVALAHPSIS 181 +GG +I+ E + KG+D+ V+ LF+NTPARLKYMK++ TELG+I+D +YR+A++HP +S Sbjct: 126 KGGDIIKQEKTASRKGTDITVQNLFFNTPARLKYMKTIHTELGNITDIVYRIAMSHPEVS 185 Query: 182 FTLHHNGNQLLHTLGNGDLLQVIAAVYGTSAAKAMLPLAAEDPDYRISGYVSRPEWTRSN 241 L HN +LLHT GNGD+ QV+A++Y AK ++P+ AE D+ I GYV+ PE TR++ Sbjct: 186 LKLFHNEKKLLHTSGNGDVRQVLASIYSIQVAKKLVPIEAESLDFTIKGYVTLPEVTRAS 245 Query: 242 RNAVTTIVGGRYIRSNGLNAAIMRAYHTLLPINRYPLLVLQLEMHPSLVDVNVHPAKLEV 301 RN ++TIV GRY+R+ L AI + YHTLLP+ RYP+ L +EM P LVDVNVHPAKLEV Sbjct: 246 RNYMSTIVNGRYVRNFVLMKAIQQGYHTLLPVGRYPIGFLSIEMDPMLVDVNVHPAKLEV 305 Query: 302 RFSKEAELYAFVEQEIRKVLMGQSLIPRPSKEIIGAKGSSSFIQEQFAFSKGAVPPP 358 RFSKE EL +E+ ++ LIP + K +QEQF F P Sbjct: 306 RFSKEQELLKLIEETLQAAFKKIQLIPD-AGVTTKKKEKDESVQEQFQFEHAKPKEP 361 >ref|NP_980099.1| DNA mismatch repair protein MutL [Bacillus cereus ATCC 10987] gb|AAS42707.1| DNA mismatch repair protein MutL [Bacillus cereus ATCC 10987] Length = 647 Score = 397 bits (1020), Expect = e-109, Method: Compositional matrix adjust. Identities = 197/357 (55%), Positives = 253/357 (70%), Gaps = 2/357 (0%) Query: 2 LDEHIANQIAAGEVVERPASVVKELVENAIDAGSTRIEVSVEEGGLQSIRVKDNGSGIDP 61 LD+ ++N IAAGEVVERPASVVKELVEN+IDA ST IE+ +EE GL IR+ DNG GI Sbjct: 7 LDDQLSNLIAAGEVVERPASVVKELVENSIDANSTSIEIHLEEAGLSKIRIIDNGDGIAE 66 Query: 62 EDCETAFYRHATSKIVNGRDLFQITSLGFRGEALPSIASVSKLSLLTSSNEDGKGRALDI 121 EDC AF RHATSKI + DLF+I +LGFRGEALPSIASVS+L L+TS+ D G L I Sbjct: 67 EDCIVAFERHATSKIKDENDLFRIRTLGFRGEALPSIASVSELELITSTG-DAPGTHLII 125 Query: 122 EGGKLIRNEDEPAGKGSDLAVRELFYNTPARLKYMKSVQTELGHISDTMYRVALAHPSIS 181 +GG +I+ E + KG+D+ V+ LF+NTPARLKYMK++ TELG+I+D +YR+A++HP +S Sbjct: 126 KGGDIIKQEKTASRKGTDITVQNLFFNTPARLKYMKTIHTELGNITDIVYRIAMSHPEVS 185 Query: 182 FTLHHNGNQLLHTLGNGDLLQVIAAVYGTSAAKAMLPLAAEDPDYRISGYVSRPEWTRSN 241 L HN +LLHT GNGD+ QV+A++Y AK ++P+ AE D+ I GYV+ PE TR++ Sbjct: 186 LKLFHNEKKLLHTSGNGDVRQVLASIYSIQVAKKLVPIEAESLDFTIKGYVTLPEVTRAS 245 Query: 242 RNAVTTIVGGRYIRSNGLNAAIMRAYHTLLPINRYPLLVLQLEMHPSLVDVNVHPAKLEV 301 RN ++TIV GRY+R+ L AI + YHTLLP+ RYP+ L +EM P LVDVNVHPAKLEV Sbjct: 246 RNYMSTIVNGRYVRNFVLMKAIQQGYHTLLPVGRYPIGFLSIEMDPMLVDVNVHPAKLEV 305 Query: 302 RFSKEAELYAFVEQEIRKVLMGQSLIPRPSKEIIGAKGSSSFIQEQFAFSKGAVPPP 358 RFSKE EL +E+ ++ LIP + K +QEQF F P Sbjct: 306 RFSKEQELLKLIEETLQAAFKKIQLIP-DAGVTTKKKEKDESVQEQFKFEHAKPKEP 361 >ref|NP_657734.1| DNA_mis_repair, DNA mismatch repair protein [Bacillus anthracis A2012] ref|NP_846151.1| DNA mismatch repair protein MutL [Bacillus anthracis str. Ames] gb|AAP27637.1| DNA mismatch repair protein MutL [Bacillus anthracis str. Ames] Length = 626 Score = 397 bits (1020), Expect = e-109, Method: Compositional matrix adjust. Identities = 197/357 (55%), Positives = 253/357 (70%), Gaps = 2/357 (0%) Query: 2 LDEHIANQIAAGEVVERPASVVKELVENAIDAGSTRIEVSVEEGGLQSIRVKDNGSGIDP 61 LD+ ++N IAAGEVVERPASVVKELVEN+IDA ST IE+ +EE GL IR+ DNG GI Sbjct: 7 LDDQLSNLIAAGEVVERPASVVKELVENSIDANSTSIEIHLEEAGLSKIRIIDNGDGIAE 66 Query: 62 EDCETAFYRHATSKIVNGRDLFQITSLGFRGEALPSIASVSKLSLLTSSNEDGKGRALDI 121 EDC AF RHATSKI + DLF+I +LGFRGEALPSIASVS+L L+TS+ D G L I Sbjct: 67 EDCIVAFERHATSKIKDENDLFRIRTLGFRGEALPSIASVSELELITSTG-DAPGTHLII 125 Query: 122 EGGKLIRNEDEPAGKGSDLAVRELFYNTPARLKYMKSVQTELGHISDTMYRVALAHPSIS 181 +GG +I+ E + KG+D+ V+ LF+NTPARLKYMK++ TELG+I+D +YR+A++HP +S Sbjct: 126 KGGDIIKQEKTASRKGTDITVQNLFFNTPARLKYMKTIHTELGNITDIVYRIAMSHPEVS 185 Query: 182 FTLHHNGNQLLHTLGNGDLLQVIAAVYGTSAAKAMLPLAAEDPDYRISGYVSRPEWTRSN 241 L HN +LLHT GNGD+ QV+A++Y AK ++P+ AE D+ I GYV+ PE TR++ Sbjct: 186 LKLFHNEKKLLHTSGNGDVRQVLASIYSIQVAKKLVPIEAESLDFTIKGYVTLPEVTRAS 245 Query: 242 RNAVTTIVGGRYIRSNGLNAAIMRAYHTLLPINRYPLLVLQLEMHPSLVDVNVHPAKLEV 301 RN ++TIV GRY+R+ L AI + YHTLLP+ RYP+ L +EM P LVDVNVHPAKLEV Sbjct: 246 RNYMSTIVNGRYVRNFVLMKAIQQGYHTLLPVGRYPIGFLSIEMDPMLVDVNVHPAKLEV 305 Query: 302 RFSKEAELYAFVEQEIRKVLMGQSLIPRPSKEIIGAKGSSSFIQEQFAFSKGAVPPP 358 RFSKE EL +E+ ++ LIP + K +QEQF F P Sbjct: 306 RFSKEQELLKLIEETLQAAFKKIQLIP-DAGVTTKKKEKDESVQEQFQFEHAKPKEP 361 >ref|NP_464929.1| DNA mismatch repair protein [Listeria monocytogenes EGD-e] sp|Q8Y788|MUTL_LISMO DNA mismatch repair protein mutL pir||AD1250 DNA mismatch repair protein [imported] - Listeria monocytogenes (strain EGD-e) emb|CAC99482.1| DNA mismatch repair protein [Listeria monocytogenes] Length = 601 Score = 393 bits (1010), Expect = e-108, Method: Compositional matrix adjust. Identities = 197/327 (60%), Positives = 245/327 (74%), Gaps = 1/327 (0%) Query: 2 LDEHIANQIAAGEVVERPASVVKELVENAIDAGSTRIEVSVEEGGLQSIRVKDNGSGIDP 61 L + ++N+IAAGEVVERPASVVKELVENAIDAGST I++ VEE GL I + DNGSGI+ Sbjct: 8 LTDALSNKIAAGEVVERPASVVKELVENAIDAGSTVIDILVEEAGLNKITIIDNGSGIEE 67 Query: 62 EDCETAFYRHATSKIVNGRDLFQITSLGFRGEALPSIASVSKLSLLTSSNEDGKGRALDI 121 ED TAF RHATSKI N DLF++ +LGFRGEALPSIASVS L++ TS+ E KG ++ + Sbjct: 68 EDVATAFLRHATSKIKNEADLFRVHTLGFRGEALPSIASVSHLAMETSTGE-TKGTSISL 126 Query: 122 EGGKLIRNEDEPAGKGSDLAVRELFYNTPARLKYMKSVQTELGHISDTMYRVALAHPSIS 181 EGGK+I + A KG+ + V +LF+NTPARLKY+KS+ TELG+I+D + R+ALAHP IS Sbjct: 127 EGGKIIEQKSGHARKGTQIEVSQLFFNTPARLKYLKSLPTELGNITDILNRLALAHPDIS 186 Query: 182 FTLHHNGNQLLHTLGNGDLLQVIAAVYGTSAAKAMLPLAAEDPDYRISGYVSRPEWTRSN 241 F HNG LL T GNGDL QVIAA+YG S AK +P+ AE D++ISGY PE RSN Sbjct: 187 FRFSHNGKPLLQTNGNGDLRQVIAAIYGISIAKKSIPVKAESLDFKISGYAVLPEVNRSN 246 Query: 242 RNAVTTIVGGRYIRSNGLNAAIMRAYHTLLPINRYPLLVLQLEMHPSLVDVNVHPAKLEV 301 RN ++TI+ GR+I++ L AI YHTLLPI R+P++VLQ+EM P +VDVNVHPAKLEV Sbjct: 247 RNYISTIINGRFIKNFALVKAIQEGYHTLLPIGRFPIIVLQIEMDPIIVDVNVHPAKLEV 306 Query: 302 RFSKEAELYAFVEQEIRKVLMGQSLIP 328 R SKE EL + Q I++ LIP Sbjct: 307 RLSKEKELGQLISQMIKEAFHKLQLIP 333 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.318 0.134 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 642,785,996 Number of extensions: 25662160 Number of successful extensions: 75552 Number of sequences better than 1.0e-05: 432 Number of HSP's gapped: 74987 Number of HSP's successfully gapped: 435 Length of query: 470 Length of database: 757,237,578 Length adjustment: 129 Effective length of query: 341 Effective length of database: 406,989,807 Effective search space: 138783524187 Effective search space used: 138783524187 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 128 (53.9 bits)