BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0504.0017.p (549 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_244314.1| two-component sensor histidine kinase [Bacillus... 147 7e-34 ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongen... 145 3e-33 ref|NP_241658.1| two-component sensor histidine kinase [Bacillus... 137 8e-31 ref|NP_782429.1| two-component sensor kinase yesM [Clostridium t... 136 1e-30 ref|NP_691698.1| hypothetical protein OB0777 [Oceanobacillus ihe... 134 4e-30 >ref|NP_244314.1| two-component sensor histidine kinase [Bacillus halodurans] pir||G84080 two-component sensor histidine kinase BH3447 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07166.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 602 Score = 147 bits (371), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 125/448 (27%), Positives = 219/448 (48%), Gaps = 40/448 (8%) Query: 108 IDSFLKTVLFSDPYISSAVFVRQS----DGKLYSQEKENRSLDTNSFPAAE--WLETMAP 161 I FL+ P I+ + V Q +LY++ N + ++ A E + + Sbjct: 101 ISKFLQNFTTLYPEIAGILVVNQQGDYLSNELYTRSSFNLNQESWYRQAVENKGIAKLIG 160 Query: 162 KPSAVAIFPTHTDQYFFRSNRKVFTIGRSLIDTSGKVTQAPKVVGTLFLDIDISLFEQFF 221 KP I T +R + +V T+ R++ID++ T K G + +D+ + + E+ Sbjct: 161 KPQGRRI----TSHVHYRED-EVVTVVRAIIDST---TGEEK--GVILIDLKLRVIEEAV 210 Query: 222 RELSLGAKDELYLLDGEGHVYFS---------------NQNLPEGAVAAAVQTNREMIGL 266 R++ LG L ++D +G +S +QN G V+ R + + Sbjct: 211 RDVRLGKSGYLMVVDQKGDPIYSPAPSIMYEQSFDHRFSQNY--GIFTEEVEGERYQL-M 267 Query: 267 SEDIPFLNGRVIARIHRGSLFEQLLSVRAAVYIAIMICAFVMVVMGAWFSRRLAAPIREI 326 + F +I E++ + V + FV + + S ++ PI ++ Sbjct: 268 YQQSAFTGWTLIGVFSTDQSVEEVQQILFYVVTFVFFVCFVGITASYFLSYTISRPINQL 327 Query: 327 IRQMTVVESGRLDTRLSVNTNDEMGRLAHGFNRMVERLQIHIDEAYVAQIKQKQTELNAL 386 + M ESG L +R DE+GRL FN M+E++ I + K+++ EL++L Sbjct: 328 MLAMQKAESGDLTSRYEGEEQDEVGRLGRSFNTMIEQIGKLISLTERQERKKREAELHSL 387 Query: 387 KSQIRPHYLYNTLEVIRMNAVDKEAGEVADMILALSNELKYVIDYGEDRASIRSELEHLQ 446 ++ I+PH+LYNTL+ I+ A K A +VAD++ ALS + + G + E+EH++ Sbjct: 388 QANIKPHFLYNTLDTIQWMARKKNASDVADLVGALSKLFRIGLSKGGTIIPLVDEIEHIK 447 Query: 447 NYFYIISVRFENR--YELVLDIAPEVQLDWPILKLSLQPIVENAVQHGLRQ-QGKGTVGI 503 NY I SVR++N+ Y LV+ P ILK+ LQPIVENA+ HG+++ +G G + I Sbjct: 448 NYLQIQSVRYKNKLNYSLVM---PSNMERLSILKIVLQPIVENAIYHGIKERRGPGLITI 504 Query: 504 TVEKKDRVLAVTIYDDGVGMSREALARI 531 E+++ +L + I D+G G+ E L ++ Sbjct: 505 EAERENDMLIIRIRDNGKGIKPETLQQL 532 >ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongensis] gb|AAM25485.1| predicted ATPase [Thermoanaerobacter tengcongensis] Length = 593 Score = 145 bits (366), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 119/449 (26%), Positives = 216/449 (48%), Gaps = 37/449 (8%) Query: 112 LKTVLFSDPYISS-AVFVRQSDGKLYSQEKENRSLDTNSFPAAEWLETMAPKPSAVAIFP 170 L ++L S YIS A++ Q D +S + +D + + K A Sbjct: 102 LASLLASKDYISFIALYSFQGDKYYFSNDSSTLIMDLELIKRTSFYREVLEKNGAPMWLS 161 Query: 171 THTDQY--FFRSNRKVFTIGRSLIDTSGKVTQAPKVVGTLFLDIDISLFEQFFRELSLGA 228 + ++N + R L+D + T P+ G L + I+I E+ + E Sbjct: 162 LENLPFDLIIKNNYPKIAMARVLLDFN---TYKPE--GLLVICINIPTIEKVYSENLKEK 216 Query: 229 KDELYLLDGEGHVYFSNQNLPEGAVAAAVQT-----------------NREMIGLSEDIP 271 + ++ D G++ S ++ G + Q + +++ S IP Sbjct: 217 ESAFFIADRNGNI-ISFKSTFSGFTPKSAQNILAKYLKDKQNVVININSSKLLVTSSPIP 275 Query: 272 FLNGRVIARIHRGSLFEQLLSVRAAV---YIAIMI-CAFVMVVMGAWFSRRLAAPIREII 327 + R+++ + SL + S+R + Y+ I++ C ++ +FSR L P+ + Sbjct: 276 TSDWRLVSVV---SLKNAINSIRISFIEFYLRILVFCLLFAFLVSMYFSRALTHPLERLA 332 Query: 328 RQMTVVESGRLDTRLSV--NTNDEMGRLAHGFNRMVERLQIHIDEAYVAQIKQKQTELNA 385 M V G L+ ++ ++ DE+ + +NRMVER+ I+ +I +++ EL A Sbjct: 333 NSMKKVRQGNLEEKVEFEYHSKDEIAIVIKEYNRMVERINDLINRILKLEINKREAELKA 392 Query: 386 LKSQIRPHYLYNTLEVIRMNAVDKEAGEVADMILALSNELKYVIDYGEDRASIRSELEHL 445 L++QI PH+LYNTL+ I A + E+++MI +LS + ++ GE+ +R E E + Sbjct: 393 LEAQINPHFLYNTLDTIFWKAEKAKDRELSEMIYSLSRLFRLTLNRGEEFIQVRGEKELI 452 Query: 446 QNYFYIISVRFENRYELVLDIAPEVQLDWPILKLSLQPIVENAVQHGLRQQGKGT-VGIT 504 + Y ++ S R++N+++ + I+ E+ LD+ I KL LQP VENA+ HGL + + V + Sbjct: 453 ERYLFLQSKRYKNKFKYSVKISDEI-LDYYIPKLILQPFVENAIVHGLENNSEESFVEVI 511 Query: 505 VEKKDRVLAVTIYDDGVGMSREALARITR 533 EK+ L I D+G GMS E L ++ R Sbjct: 512 GEKEGENLKFIIKDNGPGMSEETLEKLKR 540 >ref|NP_241658.1| two-component sensor histidine kinase [Bacillus halodurans] pir||H83748 two-component sensor histidine kinase BH0792 [imported] - Bacillus halodurans (strain C-125) dbj|BAB04511.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 587 Score = 137 bits (344), Expect = 8e-31, Method: Compositional matrix adjust. Identities = 92/330 (27%), Positives = 170/330 (51%), Gaps = 15/330 (4%) Query: 229 KDELYLLDGEGHVYFS-----NQNLPEGAVAAAVQ--TNREMIGLSEDIPFLNGRVIARI 281 K Y++D E +V +S ++ L E A Q NR +I S I G ++A I Sbjct: 215 KGSYYIIDEELNVVYSYGDVLDEALKEIDYRATQQLVNNRYLIQSS--IEPSTGFMVASI 272 Query: 282 HRGSLFEQLLSVRAAVYIAIMICAFVMVVMGAWFSRRLAAPIREIIRQMTVVESGRLDTR 341 S QL + +++ I++ V + + R + ++++ M V+SG+L R Sbjct: 273 VPRSELSQLFHYKITMFLLILLLTVVSIALPYVSLRGYLTRVNDLVQTMKEVQSGQLSVR 332 Query: 342 LSV-NTNDEMGRLAHGFNRMVERLQIHIDEAYVAQIKQKQTELNALKSQIRPHYLYNTLE 400 + N +D++ +++ FN ++ L+ +I++ Y +++KQ + EL L+SQI PH+LYNTLE Sbjct: 333 IETGNVDDDLAMISNTFNETLDELEDYIEKVYFSKLKQTEAELANLQSQINPHFLYNTLE 392 Query: 401 VIRMNAVDKEAGEVADMILALSNELKYVIDYGEDRASIRSELEHLQNYFYIISVRFENRY 460 IRM ++ + A MI+ LS +Y + D +I EL+H++ Y + ++RF N Sbjct: 393 AIRMKSLSEGGRTTAKMIVQLSYLFRYSLK-SADLVTIGDELQHVEQYVELFNIRFPN-- 449 Query: 461 ELVLDIA-PEVQLDWPILKLSLQPIVENAVQHGL-RQQGKGTVGITVEKKDRVLAVTIYD 518 +L +A E + + LQP++EN + HG R++ + I +++K++ L + I D Sbjct: 450 QLTFQVAVEEKHKHYVVPPFILQPLIENFLIHGFKRERDDNQINIIIQEKEQTLQIQIMD 509 Query: 519 DGVGMSREALARITRTXXXXRNRKRPAKMW 548 +G G+ R+ + I N ++ Sbjct: 510 NGKGIPRKKVEEINERLSMTENSSHSIGLF 539 >ref|NP_782429.1| two-component sensor kinase yesM [Clostridium tetani E88] gb|AAO36366.1| two-component sensor kinase yesM [Clostridium tetani E88] Length = 577 Score = 136 bits (343), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 71/214 (33%), Positives = 123/214 (57%), Gaps = 2/214 (0%) Query: 316 SRRLAAPIREIIRQMTVVESGRLDTRLSVNTNDEMGRLAHGFNRMVERLQIHIDEAYVAQ 375 S + PI + M + G D+ + NDE+ L FN+M+ ++ I++ Y + Sbjct: 303 SGSIVKPIHRLKSNMLEISKGNFDSYYEIKNNDEISILGQVFNQMLTDIKRLINKVYQVE 362 Query: 376 IKQKQTELNALKSQIRPHYLYNTLEVIRMNAVDKEAGEVADMILALSNELKYVIDYGEDR 435 +++ EL L+SQI PH+LYNTL+ I+ A++ A EV DMI LSN + + G++ Sbjct: 363 KQKRSAELRVLQSQINPHFLYNTLDTIQWKALEYNAFEVVDMINYLSNFFRISLSDGKEF 422 Query: 436 ASIRSELEHLQNYFYIISVRFENRYELVLDIAPEVQLDWPILKLSLQPIVENAVQHGLR- 494 +I E+ H+ NY I +R++++ +D+ + + I KL +QP+VEN++ HGL+ Sbjct: 423 ITISDEVAHVSNYLEIQKIRYKDKISYSMDVDSSLD-QYLIPKLIVQPLVENSIYHGLKL 481 Query: 495 QQGKGTVGITVEKKDRVLAVTIYDDGVGMSREAL 528 Q+ KG + +++ KD L + + D+G+GM E L Sbjct: 482 QKHKGIINVSISSKDGFLFIKVIDNGLGMDVEQL 515 >ref|NP_691698.1| hypothetical protein OB0777 [Oceanobacillus iheyensis HTE831] dbj|BAC12733.1| hypothetical conserved protein [Oceanobacillus iheyensis HTE831] Length = 577 Score = 134 bits (338), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 82/251 (32%), Positives = 137/251 (54%), Gaps = 8/251 (3%) Query: 278 IARIHRGSLFEQLLSVRAAVYIAIMICAFVMVVMGAWFSRRLAAPIREIIRQMTVVESGR 337 + I L E L VRA + I I ++ +F I E+ +Q VE+G Sbjct: 272 VTAIDEDKLAEDLTEVRALIGFLIGILFLAGLLFFTFFYHSNIKRILELTKQTKQVETGN 331 Query: 338 LDTRLSVNTNDEMGRLAHGFNRMVERLQIHIDEAYVAQIKQKQTELNALKSQIRPHYLYN 397 L + V++NDE+G+L + FN+MV+ +Q HID Y +IKQK++EL L++QI PH+LYN Sbjct: 332 LTASVHVDSNDEIGKLGYRFNKMVKTIQKHIDTEYRLKIKQKESELKVLQNQINPHFLYN 391 Query: 398 TLEVIRMNAVDKEAGEVADMILALSNELKYVIDYGEDRASIRSELEHLQNYFYIISVRFE 457 TL++IR NA + A E + +I LS + ++ G+ E+E+ Q Y + R Sbjct: 392 TLDMIRWNARLENAPETSQLIERLSKIFRMNLNNGKSLVKFEEEVEYSQAYLELQKKRLG 451 Query: 458 NR--YELVLDIAPEVQLD-WPILKLSLQPIVENAVQHGLRQQGK-GTVGITVEKKDRVLA 513 + Y+LV+ E QL + ++K +QP++EN++QHG + + G + I + + Sbjct: 452 EKLDYQLVM----EEQLKGYYVMKQMIQPLIENSIQHGFKNLPRQGIIRIHCYRDENQAV 507 Query: 514 VTIYDDGVGMS 524 + + D+G G + Sbjct: 508 IDVIDNGWGFN 518 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.322 0.136 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 731,862,121 Number of extensions: 29449257 Number of successful extensions: 84686 Number of sequences better than 1.0e-05: 218 Number of HSP's gapped: 84609 Number of HSP's successfully gapped: 218 Length of query: 549 Length of database: 757,237,578 Length adjustment: 131 Effective length of query: 418 Effective length of database: 401,559,609 Effective search space: 167851916562 Effective search space used: 167851916562 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 128 (53.9 bits)