BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0502.0010.p (417 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_813589.1| L-serine dehydratase [Bacteroides thetaiotaomic... 355 2e-96 ref|NP_604003.1| L-serine dehydratase [Fusobacterium nucleatum s... 353 5e-96 ref|ZP_00129068.1| COG1760: L-serine deaminase [Desulfovibrio de... 353 6e-96 ref|NP_904433.1| L-serine dehydratase, iron-sulfur-dependent, si... 348 1e-94 ref|ZP_00129003.1| COG1760: L-serine deaminase [Desulfovibrio de... 287 4e-76 >ref|NP_813589.1| L-serine dehydratase [Bacteroides thetaiotaomicron VPI-5482] gb|AAO79783.1| L-serine dehydratase [Bacteroides thetaiotaomicron VPI-5482] Length = 411 Score = 355 bits (910), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 198/409 (48%), Positives = 253/409 (61%), Gaps = 5/409 (1%) Query: 9 LRRDKGAMRSLTELYKIGSGPSSSHTMGPEKAARIFKAENEDADQFKALIYGSLAKTGKG 68 L + +M+S+ ELY+IG+GPSSSHTMGP KAA +F + DA FK +YGSLA TGKG Sbjct: 3 LTKAHPSMKSIKELYRIGTGPSSSHTMGPRKAAEMFVERHPDAASFKVTLYGSLAATGKG 62 Query: 69 HMTDKAIIRALSPASAEVEFVPQPDFVLP-HPNTMDLFAYQ-DGQQTNSMRAVSIGGGDI 126 HMTD AII L PA A VE V QP LP HPN M A D + + SIGGG + Sbjct: 63 HMTDVAIIDTLQPA-APVEIVWQPKVFLPFHPNGMTFAALDADNKILENWTVYSIGGGAL 121 Query: 127 VIEGREET-HGPDVYPENSFAEISAFCKANHIRLSDYVEQREGNQIWEFLQGIWEAMKRS 185 T P+VY N+ EI +C+ +YV++ E IW++L +W+ MK + Sbjct: 122 AENNDNPTIESPEVYGMNNMTEILQWCERTGKSYWEYVKECENEDIWDYLAEVWDTMKDA 181 Query: 186 IDEGLSVTGILEGGLHVERKAKYLYHQRDMDESPETRENRIVSAYAFAVNEQNAAAGTVV 245 I GL G+L G L++ RKA Y+ R + +V +YA AV+E+NA+ G +V Sbjct: 182 IHRGLEAEGVLPGPLNLRRKAS-TYYIRATGYKQSLQSRGLVFSYALAVSEENASGGKIV 240 Query: 246 TAPTCGASGVVPASLRYMQEKLQVPDERILRALAVGGLIGNLVKQNASISGAQCGCQAEV 305 TAPTCG+ GV+PA L ++Q+ D RILRALA GLIGN+VK NASISGA+ GCQ EV Sbjct: 241 TAPTCGSCGVMPAVLYHLQKSRDFSDMRILRALATAGLIGNIVKFNASISGAEVGCQGEV 300 Query: 306 XXXXXXXXXXXXXXXXXXIDQIEYAAEVAMEHHLGLTCDPINGLVQIPCIERNAVGAMRA 365 QIEYAAE+ +EHHLG+TCDP+ GLVQIPCIERNA A RA Sbjct: 301 GVACAMASAAANQLFGGSPAQIEYAAEMGLEHHLGMTCDPVCGLVQIPCIERNAYAAARA 360 Query: 366 INALSLAKFLSGTRKISFDLVVQTMYETGQDMNSSYRETSEGGLAKLYK 414 ++A + F G ++SFD VVQ M +TG D+ S Y+ETSEGGLAK Y+ Sbjct: 361 LDANLYSAFTDGMHRVSFDKVVQVMKQTGHDLPSLYKETSEGGLAKDYQ 409 >ref|NP_604003.1| L-serine dehydratase [Fusobacterium nucleatum subsp. nucleatum ATCC 25586] gb|AAL95302.1| L-serine dehydratase [Fusobacterium nucleatum subsp. nucleatum ATCC 25586] Length = 408 Score = 353 bits (905), Expect = 5e-96, Method: Compositional matrix adjust. Identities = 191/402 (47%), Positives = 254/402 (63%), Gaps = 7/402 (1%) Query: 16 MRSLTELYKIGSGPSSSHTMGPEKAARIFKAENEDADQFKALIYGSLAKTGKGHMTDKAI 75 M +L EL+KIG+GPSSSHT+GPE+A + K + +AD + ++GSLA TGKGH TDK I Sbjct: 1 MDTLKELFKIGAGPSSSHTIGPERATKRVKEKFPNADSYIVELWGSLAATGKGHYTDKII 60 Query: 76 IRALSPASAEVEFVPQPDFVLP-HPNTMDLFAY-QDGQQTNSMRAVSIGGGDI--VIEGR 131 I P VE + +P+FV H N M A +D +Q S+GGG I E Sbjct: 61 IETFKPIP--VEIIWKPEFVHELHTNGMKFIALDKDKKQIGEWIVFSVGGGTIRDYDELM 118 Query: 132 EETHGPDVYPENSFAEISAFCKANHIRLSDYVEQREGNQIWEFLQGIWEAMKRSIDEGLS 191 +++ +VYP NS EI +CK N +L YVE+ EG IW+ L+ I +AM ++ GL Sbjct: 119 DKSPKKEVYPLNSMKEIVKWCKDNKKQLWQYVEECEGPSIWQHLRYIDQAMTDAVKRGLE 178 Query: 192 VTGILEGGLHVERKAKYLYHQRDMDESPETRENRIVSAYAFAVNEQNAAAGTVVTAPTCG 251 +G + G ++A+ +Y + + N++ AYA AV+E+NA+ G VVTAPTCG Sbjct: 179 KSGDVPGPFKYPKRAREMYEKALSKRASLIFTNKVF-AYALAVSEENASMGQVVTAPTCG 237 Query: 252 ASGVVPASLRYMQEKLQVPDERILRALAVGGLIGNLVKQNASISGAQCGCQAEVXXXXXX 311 ASGV+P LR M+E+ ++ ++ ILR LA+ GLIGNLVK NA+ISGA+ GCQAEV Sbjct: 238 ASGVIPGVLRGMKEEYELVEKHILRGLAIAGLIGNLVKYNATISGAEGGCQAEVGTACSM 297 Query: 312 XXXXXXXXXXXXIDQIEYAAEVAMEHHLGLTCDPINGLVQIPCIERNAVGAMRAINALSL 371 DQIEYAAE AMEHHLG+TCDP+ G V IPCIERNA+ A+RAIN + Sbjct: 298 AAAMATYFMGGNTDQIEYAAESAMEHHLGMTCDPVGGYVIIPCIERNAICAVRAINTATY 357 Query: 372 AKFLSGTRKISFDLVVQTMYETGQDMNSSYRETSEGGLAKLY 413 G ISFD V++TM ETG+DM S+Y+ETS+GGLAK Y Sbjct: 358 CMSTDGKHTISFDEVIKTMKETGKDMCSAYKETSDGGLAKYY 399 >ref|ZP_00129068.1| COG1760: L-serine deaminase [Desulfovibrio desulfuricans G20] Length = 410 Score = 353 bits (905), Expect = 6e-96, Method: Compositional matrix adjust. Identities = 193/403 (47%), Positives = 247/403 (61%), Gaps = 11/403 (2%) Query: 16 MRSLTELYKIGSGPSSSHTMGPEKAARIFKAENEDADQFKALIYGSLAKTGKGHMTDKAI 75 M SL ELYK+G+GPSSSHTMGP+KAA F A ++ + GSLA TGKGH+TD I Sbjct: 1 MDSLKELYKVGNGPSSSHTMGPQKAATEFLRRTPQAAHYRVTLLGSLAATGKGHLTDWII 60 Query: 76 IRALSPASAEVEFVPQPDFVLP-HPNTMDLFAYQDGQ------QTNSMRAVSIGGGDIVI 128 + L + V +P+ V P H N M +F D Q ++ S+GGG I Sbjct: 61 KKTLGEERTTI--VWKPEEVRPFHTNGM-VFEALDAQGNVPEDPASTWEVYSVGGGTIAE 117 Query: 129 EGREETHGPDVYPENSFAEISAFCKANHIRLSDYVEQREGNQIWEFLQGIWEAMKRSIDE 188 + Y + I C+A++I L +YVE +EG +W FLQ IW+AM+ SI+ Sbjct: 118 PDSLTRGAGNFYSLTTLTAIMGHCRADNIELWEYVESQEGPGLWPFLQDIWQAMQDSIER 177 Query: 189 GLSVTGILEGGLHVERKAKYLYHQRDMDESPETRENRIVSAYAFAVNEQNAAAGTVVTAP 248 GL TG+L G L RKA Y + + +S R + AYA AV+E+NA+ G VVTAP Sbjct: 178 GLGKTGLLPGDLRYPRKANAFYKKARI-QSGRLRSTGMTFAYALAVSEENASGGLVVTAP 236 Query: 249 TCGASGVVPASLRYMQEKLQVPDERILRALAVGGLIGNLVKQNASISGAQCGCQAEVXXX 308 TCG++G+VPA LR ++E + D IL+ALAVGGL+GNLVK+NASISGA+ GCQ EV Sbjct: 237 TCGSAGLVPAVLRSLKEDYSLADTEILKALAVGGLVGNLVKENASISGAEVGCQGEVGTA 296 Query: 309 XXXXXXXXXXXXXXXIDQIEYAAEVAMEHHLGLTCDPINGLVQIPCIERNAVGAMRAINA 368 QI+YAAE+A+EHHLG+TCDP+ G VQ+PCIERNAV A+RAINA Sbjct: 297 CAMAAAMTAYLFGGTHMQIDYAAEMALEHHLGMTCDPVGGYVQVPCIERNAVSAIRAINA 356 Query: 369 LSLAKFLSGTRKISFDLVVQTMYETGQDMNSSYRETSEGGLAK 411 F G +ISFD VVQTM ETG+D+ YRETS GLAK Sbjct: 357 AEYTLFTDGNHRISFDQVVQTMGETGRDLKCGYRETSLAGLAK 399 >ref|NP_904433.1| L-serine dehydratase, iron-sulfur-dependent, single chain form [Porphyromonas gingivalis W83] gb|AAQ65332.1| L-serine dehydratase, iron-sulfur-dependent, single chain form [Porphyromonas gingivalis W83] Length = 399 Score = 348 bits (893), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 192/400 (48%), Positives = 252/400 (63%), Gaps = 4/400 (1%) Query: 16 MRSLTELYKIGSGPSSSHTMGPEKAARIFKAENEDADQFKALIYGSLAKTGKGHMTDKAI 75 M S+T++Y+IG GPSSSHT+GP +AA +F N A F+ +YGSLA TGKGH+TD AI Sbjct: 1 MESITQIYRIGYGPSSSHTIGPRRAAEMFLDRNPRATSFRVTLYGSLAATGKGHLTDAAI 60 Query: 76 IRALSPASAEVEFVPQPD-FVLPHPNTMDLFAY-QDGQQTNSMRAVSIGGGDIVIEGREE 133 + L A A E V +P+ F HPN M ++ ++G+Q + SIGGG + E E Sbjct: 61 LAVLE-AKAPTEIVWKPEIFQNFHPNGMLFESFDKEGKQLDDWLIYSIGGGVLANEHFNE 119 Query: 134 THGPDVYPENSFAEISAFCKANHIRLSDYVEQREGNQIWEFLQGIWEAMKRSIDEGLSVT 193 G +VYP + A+I + +YVE+ E IW++L +W M+ +I EGL Sbjct: 120 QRGREVYPLSKMADILDELNRRGLSYWEYVEENEDPDIWDYLAEVWSVMRSAIQEGLDAE 179 Query: 194 GILEGGLHVERKAKYLYHQRDMDESPETRENRIVSAYAFAVNEQNAAAGTVVTAPTCGAS 253 G+L GGL V RKA Y R SP R V AYA AV+EQNA+ G +VTAPTCG+ Sbjct: 180 GVLPGGLGVRRKAAS-YLIRAQGYSPGVRSRGNVYAYALAVSEQNASGGKIVTAPTCGSC 238 Query: 254 GVVPASLRYMQEKLQVPDERILRALAVGGLIGNLVKQNASISGAQCGCQAEVXXXXXXXX 313 GVVPA L ++Q+ D+RILRALA GL N+V+ NASISGA+ GCQ EV Sbjct: 239 GVVPAVLHHLQQTRDFSDKRILRALATAGLFANVVRTNASISGAEVGCQGEVGVACAMGA 298 Query: 314 XXXXXXXXXXIDQIEYAAEVAMEHHLGLTCDPINGLVQIPCIERNAVGAMRAINALSLAK 373 + QIEYAAE+A+EHHLGLTCDP+ GLVQ+PCIERNA A RA++A + A Sbjct: 299 AASSQLFGGTLSQIEYAAEMALEHHLGLTCDPVCGLVQVPCIERNAFAAARALDANTYAN 358 Query: 374 FLSGTRKISFDLVVQTMYETGQDMNSSYRETSEGGLAKLY 413 F G +ISFD VV+ M +TG+D+ S Y+ETS+GGLA ++ Sbjct: 359 FSDGRHRISFDQVVEVMRQTGKDLPSLYKETSQGGLAIVH 398 >ref|ZP_00129003.1| COG1760: L-serine deaminase [Desulfovibrio desulfuricans G20] Length = 326 Score = 287 bits (734), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 147/318 (46%), Positives = 195/318 (61%), Gaps = 4/318 (1%) Query: 98 HPNTMDLFAYQD--GQQTNSMRAVSIGGGDIVIEGREETHGPDVYPENSFAEISAFCKAN 155 HPN M LF QD G T S + S+GGG I+ E VYP A + A C+ Sbjct: 4 HPNGM-LFEAQDSNGNVTGSWKVYSVGGGAIMGEDEPRRQQQGVYPHPDLASVMALCEDK 62 Query: 156 HIRLSDYVEQREGNQIWEFLQGIWEAMKRSIDEGLSVTGILEGGLHVERKAKYLYHQRDM 215 I +YV + EG +W FL+ IW+AM+++++ GL+ G+L G + + R+A + Y R Sbjct: 63 GITYWEYVARYEGETVWPFLKTIWQAMQQALERGLTAQGVLPGSIGLRRQA-WNYMSRTK 121 Query: 216 DESPETRENRIVSAYAFAVNEQNAAAGTVVTAPTCGASGVVPASLRYMQEKLQVPDERIL 275 + V+AYA AV E+NAA G +VTAPTCG+ G+VPA L Y++E L+ ++ IL Sbjct: 122 LAHKSMHQTGKVTAYALAVAEENAAGGIIVTAPTCGSCGIVPAVLYYLRETLKATEQDIL 181 Query: 276 RALAVGGLIGNLVKQNASISGAQCGCQAEVXXXXXXXXXXXXXXXXXXIDQIEYAAEVAM 335 RALA GL GN++K NASISGA+ GCQ EV + QIEYAAE+ + Sbjct: 182 RALATAGLFGNIIKHNASISGAEVGCQGEVGSACAMAAAAATQMMGGTVRQIEYAAEMGL 241 Query: 336 EHHLGLTCDPINGLVQIPCIERNAVGAMRAINALSLAKFLSGTRKISFDLVVQTMYETGQ 395 EHHLGLTCDP++GLVQIPCIERNA A RA++ +A G +I FD VV M +TG Sbjct: 242 EHHLGLTCDPVDGLVQIPCIERNACAATRALSRAQMAILSDGMHRIPFDEVVAVMAQTGH 301 Query: 396 DMNSSYRETSEGGLAKLY 413 D+ S YRET+ GGLAK+Y Sbjct: 302 DLPSLYRETARGGLAKVY 319 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.316 0.132 0.377 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 552,339,983 Number of extensions: 21261081 Number of successful extensions: 55775 Number of sequences better than 1.0e-05: 230 Number of HSP's gapped: 55061 Number of HSP's successfully gapped: 302 Length of query: 417 Length of database: 757,237,578 Length adjustment: 128 Effective length of query: 289 Effective length of database: 409,704,906 Effective search space: 118404717834 Effective search space used: 118404717834 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 127 (53.5 bits)