BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0493.0026.p (287 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00061486.1| COG1131: ABC-type multidrug transport system,... 226 4e-58 ref|NP_736375.1| Unknown [Streptococcus agalactiae NEM316] >gi|2... 223 3e-57 ref|NP_688943.1| ABC transporter, ATP-binding protein [Streptoco... 223 4e-57 ref|NP_422360.1| ABC transporter, ATP-binding protein [Caulobact... 222 8e-57 ref|NP_763672.1| ABC transporter (ATP-binding protein) [Staphylo... 220 3e-56 >ref|ZP_00061486.1| COG1131: ABC-type multidrug transport system, ATPase component [Clostridium thermocellum ATCC 27405] Length = 286 Score = 226 bits (577), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 116/281 (41%), Positives = 181/281 (64%), Gaps = 2/281 (0%) Query: 1 MEIKAENLTRTFGTKRAIDELNFTLPEGVYGLLGDNGAGKSTLMRILVAVDHQTSGKVSF 60 ME+K EN+T+ +G + A+D N EG+YGLLG NGAGK+TL+ I++ V + G + Sbjct: 1 MELKLENITKFYGKQCALDNFNGVFTEGIYGLLGPNGAGKTTLINIIIGVLEASKGAILL 60 Query: 61 NGKDIFHMNDDYRNLVGYIPQDFEVYPAYTATEYLEYMGALKGLSKKELKHKVPEVLKFV 120 +G D+ M Y + VGY+PQ+ Y + E+L+YM A+KG+ K + ++ EVL+ V Sbjct: 61 DGSDVKKMGTKYLDKVGYLPQEPTFYKNFRVDEFLKYMCAIKGIPSKHVDSRIEEVLELV 120 Query: 121 NLEKVANKKVKTFSGGMKRRVGIAQAIINDPKILIFDEPTAGLDPHERIRFSNIISEMGQ 180 NL KKV SGGM++R+GI QAI+N P ILI DEPTAGLDP ERIRF NIIS++ + Sbjct: 121 NLTDSYKKKVGALSGGMRQRLGIGQAILNRPDILILDEPTAGLDPGERIRFRNIISKLSK 180 Query: 181 DKIILFSTHIISDIEAITTNVIILNQGKIKEQGNVQKMLSGIKGKVFTEEMDRERLASFK 240 D+I+L +THI+SD+E I V+IL +GK+ ++G +++ ++GK++ + + + Sbjct: 181 DRIVLLATHIVSDVEYIAKEVLILKKGKLVKKGTTKELERTVEGKIWNVTVSETDVEKYM 240 Query: 241 KEHLIVRIRQEENIVSVRYLGEQESGAI--VCEPTLEDYYI 279 ++LI I++ E+ + +R + E I P+LED ++ Sbjct: 241 HKYLIANIKRLEDKLQLRIVSESRPDGIAEAVAPSLEDVFL 281 >ref|NP_736375.1| Unknown [Streptococcus agalactiae NEM316] emb|CAD47601.1| Unknown [Streptococcus agalactiae NEM316] Length = 282 Score = 223 bits (569), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 111/282 (39%), Positives = 180/282 (63%), Gaps = 7/282 (2%) Query: 1 MEIKAENLTRTFGTKRAIDELNFTLPEGVYGLLGDNGAGKSTLMRILVAVDHQTSGKVSF 60 M ++ +N+T+++G K ++++++ G+YGLLG NG GK+TL+ ++ SG + + Sbjct: 1 MLLQLDNITKSYGKKIVLNQISYQFTPGLYGLLGANGTGKTTLLNLMSHFTFADSGNIYW 60 Query: 61 NGKDIFHMNDDYRNLVGYIPQDFEVYPAYTATEYLEYMGALKGLSKKELKHKVPEVLKFV 120 NG++ ++++ +G++PQ F Y +T +L Y+ LKG+ KK+ K ++P +L+ V Sbjct: 61 NGQE---QSEEFYRHIGFLPQHFRYYDQFTGIAFLNYIATLKGVDKKKAKQEIPRLLELV 117 Query: 121 NLEKVANKKVKTFSGGMKRRVGIAQAIINDPKILIFDEPTAGLDPHERIRFSNIISEMGQ 180 L V KK+ ++SGGMK+R+GIAQA+INDP+ILI DEPT GLDP ER++F +I+S++ Sbjct: 118 GLGDVGKKKISSYSGGMKQRLGIAQALINDPEILILDEPTVGLDPKERVKFRHILSQLST 177 Query: 181 DKIILFSTHIISDIEAITTNVIILNQGKIKEQGNVQKMLSGIKGKVFTEEMDRERLASFK 240 +KII+ STHI+SD+EA+ +I+L GK E GN ++L I+GKV+ E+ E S Sbjct: 178 NKIIILSTHIVSDVEAVAKEIIVLKNGKFIEHGNTAQLLKTIEGKVW--EITTEPGLSQI 235 Query: 241 KEHLIV--RIRQEENIVSVRYLGEQESGAIVCEPTLEDYYIY 280 IV ++ + + V A + PTLED+YIY Sbjct: 236 PNIAIVNEKVFSDSRVFRVVSDICPSDSAQLVVPTLEDFYIY 277 >ref|NP_688943.1| ABC transporter, ATP-binding protein [Streptococcus agalactiae 2603V/R] gb|AAN00816.1| ABC transporter, ATP-binding protein [Streptococcus agalactiae 2603V/R] Length = 282 Score = 223 bits (568), Expect = 4e-57, Method: Compositional matrix adjust. Identities = 111/282 (39%), Positives = 180/282 (63%), Gaps = 7/282 (2%) Query: 1 MEIKAENLTRTFGTKRAIDELNFTLPEGVYGLLGDNGAGKSTLMRILVAVDHQTSGKVSF 60 M ++ +N+T+++G K ++++++ G+YGLLG NG GK+TL+ ++ SG + + Sbjct: 1 MLLQLDNITKSYGKKIVLNQISYQFTPGLYGLLGANGTGKTTLLNLMSHFTLADSGNIYW 60 Query: 61 NGKDIFHMNDDYRNLVGYIPQDFEVYPAYTATEYLEYMGALKGLSKKELKHKVPEVLKFV 120 NG++ ++++ +G++PQ F Y +T +L Y+ LKG+ KK+ K ++P +L+ V Sbjct: 61 NGQE---QSEEFYRHIGFLPQHFRYYDQFTGIAFLNYIATLKGVDKKKAKQEIPRLLELV 117 Query: 121 NLEKVANKKVKTFSGGMKRRVGIAQAIINDPKILIFDEPTAGLDPHERIRFSNIISEMGQ 180 L V KK+ ++SGGMK+R+GIAQA+INDP+ILI DEPT GLDP ER++F +I+S++ Sbjct: 118 GLGDVGKKKISSYSGGMKQRLGIAQALINDPEILILDEPTVGLDPKERVKFRHILSQLST 177 Query: 181 DKIILFSTHIISDIEAITTNVIILNQGKIKEQGNVQKMLSGIKGKVFTEEMDRERLASFK 240 +KII+ STHI+SD+EA+ +I+L GK E GN ++L I+GKV+ E+ E S Sbjct: 178 NKIIILSTHIVSDVEAVAKEIIVLKNGKFIEHGNTAQLLKTIEGKVW--EITTEPGLSQI 235 Query: 241 KEHLIV--RIRQEENIVSVRYLGEQESGAIVCEPTLEDYYIY 280 IV ++ + + V A + PTLED+YIY Sbjct: 236 PNIAIVNEKVFSDSRVFRVVSDICPSDSAQLVVPTLEDFYIY 277 >ref|NP_422360.1| ABC transporter, ATP-binding protein [Caulobacter crescentus CB15] pir||D87691 ABC transporter, ATP-binding protein CC3566 [imported] - Caulobacter crescentus gb|AAK25528.1| ABC transporter, ATP-binding protein [Caulobacter crescentus CB15] Length = 294 Score = 222 bits (565), Expect = 8e-57, Method: Compositional matrix adjust. Identities = 111/277 (40%), Positives = 172/277 (62%), Gaps = 4/277 (1%) Query: 6 ENLTRTFGT-KRAIDELNFTLPEGVYGLLGDNGAGKSTLMRILVAVDHQTSGKVSFNGKD 64 ENLT +G RA+DE++ T+P G+YGLLG NGAGKSTLMR + + TSG + F D Sbjct: 5 ENLTHVYGNGTRALDEVSLTIPRGMYGLLGPNGAGKSTLMRTIATLQAPTSGHIRFGDID 64 Query: 65 IFHMNDDYRNLVGYIPQDFEVYPAYTATEYLEYMGALKGLSK-KELKHKVPEVLKFVNLE 123 + ++ R +GY+PQDF VYP +A + L++M LKG+S KE K V +L VNL Sbjct: 65 VLKHPEELRKTLGYLPQDFGVYPRVSAYDMLDHMAVLKGISGGKERKATVEHLLNQVNLW 124 Query: 124 KVANKKVKTFSGGMKRRVGIAQAIINDPKILIFDEPTAGLDPHERIRFSNIISEMGQDKI 183 V K + FSGGM++R GIAQA+I DP+++I DEPTAGLDP ER RF N+++E+G++ + Sbjct: 125 DVRKKAIAGFSGGMRQRFGIAQALIGDPRLIIVDEPTAGLDPEERNRFLNLLAEIGENVV 184 Query: 184 ILFSTHIISDIEAITTNVIILNQGKIKEQGNVQKMLSGIKGKVFTEEMDRERLASFKKEH 243 ++ STHI+ D+ + + I+ G I +G +++ +KG+++ + +D+ L + K + Sbjct: 185 VILSTHIVEDVSDLCPAMAIICNGAIVREGAPADLVAQLKGRIWKKIIDKAELEAAKARY 244 Query: 244 LIV--RIRQEENIVSVRYLGEQESGAIVCEPTLEDYY 278 ++ R+ ++ + + G E LED Y Sbjct: 245 KVISTRLLAGRTVIHIESETDPGDGFTAVEGGLEDVY 281 >ref|NP_763672.1| ABC transporter (ATP-binding protein) [Staphylococcus epidermidis ATCC 12228] gb|AAO03714.1| ABC transporter (ATP-binding protein) [Staphylococcus epidermidis ATCC 12228] Length = 301 Score = 220 bits (560), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 110/283 (38%), Positives = 183/283 (64%), Gaps = 4/283 (1%) Query: 2 EIKAENLTRTF-GTKRAIDELNFTLPEGVYGLLGDNGAGKSTLMRILVAVDHQTSGKVSF 60 EI + L++++ G K A++ L+ +P G++G+LG NG+GKSTLM I+ + + G V+ Sbjct: 3 EIVIKGLSKSYDGKKDALNSLDLVIPNGMFGILGRNGSGKSTLMNIIATILQPSKGTVTI 62 Query: 61 NGKDIFHMNDDYRNLVGYIPQDFEVYPAYTATEYLEYMGALKGLSKKELKHKVPEVLKFV 120 NG +I + + R ++GY+PQDF+ YP +E L Y+G L +++K+ V +L+ V Sbjct: 63 NGIEIKN-SQKIRQMIGYLPQDFDFYPNMKVSEVLYYLGFLSKINQKDFDKYVDLILRKV 121 Query: 121 NLEKVANKKVKTFSGGMKRRVGIAQAIINDPKILIFDEPTAGLDPHERIRFSNIISEMGQ 180 NL NKKVK+ SGGMK+R+GIAQAI++DPK++I DEPTAGLDP ER+R N++S++ + Sbjct: 122 NLIDYKNKKVKSLSGGMKKRLGIAQAILHDPKVIIVDEPTAGLDPEERVRLRNLLSDLAE 181 Query: 181 DKIILFSTHIISDIEAITTNVIILNQGKIKEQGNVQKMLSGIKGKVFTEEMDRERLASFK 240 +KI++ STHI+SDIE+ + IL++G + +G++ ++ ++ + L SF+ Sbjct: 182 NKIVIISTHIVSDIESTCNKIAILDKGSLVYKGDIPSLIQQSDDHIYEINLSPSELESFR 241 Query: 241 KEHLIVRIRQE-ENIVSVRYLGEQE-SGAIVCEPTLEDYYIYL 281 + L + QE +N + VR++ E + + A + ED Y+Y Sbjct: 242 ENDLFITKTQEIDNKLKVRFISETKVANAKKVKADFEDAYMYF 284 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.318 0.138 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 425,461,953 Number of extensions: 18090741 Number of successful extensions: 119484 Number of sequences better than 1.0e-05: 20279 Number of HSP's gapped: 97198 Number of HSP's successfully gapped: 21508 Length of query: 287 Length of database: 757,237,578 Length adjustment: 124 Effective length of query: 163 Effective length of database: 420,565,302 Effective search space: 68552144226 Effective search space used: 68552144226 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 125 (52.8 bits)