BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0493.0008.p (215 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_346816.1| Response regulator, CheY-like receiver domain a... 283 2e-75 ref|NP_348871.1| Response regulator (CheY-like receiver domain a... 211 7e-54 ref|NP_965466.1| two-component system response regulator [Lactob... 191 7e-48 ref|ZP_00109115.1| COG2197: Response regulator containing a CheY... 189 4e-47 ref|NP_346881.1| Response regulator (CheY-like recever domain an... 188 6e-47 >ref|NP_346816.1| Response regulator, CheY-like receiver domain and HTH DNA-binding domain [Clostridium acetobutylicum] pir||A96921 response regulator, CheY-like receiver domain and HTH DNA-binding domain [imported] - Clostridium acetobutylicum gb|AAK78156.1| Response regulator, CheY-like receiver domain and HTH DNA-binding domain [Clostridium acetobutylicum] Length = 213 Score = 283 bits (724), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 138/215 (64%), Positives = 179/215 (83%), Gaps = 2/215 (0%) Query: 1 MVDIMIVDDQQIVREGLKMILSLHEEINVIGEASNGEEALELLSYTSPEVILMDIKMPVM 60 M+D++IVDDQ+IVREGLKMIL L+ E NVIGEASNG E L LL + SP VILMDI+MPVM Sbjct: 1 MIDVIIVDDQEIVREGLKMILGLNNEFNVIGEASNGAELLTLLEHQSPNVILMDIRMPVM 60 Query: 61 NGIEATKLVKAKYPGIKVIILTTFNDSEYIFTGLKNGADGYILKDSGSQEIISSIKTACE 120 +GIEAT+LVK YP +KVIILTTFN+ E+IF LKNGADGY+LKD+GS+EI +SIK ACE Sbjct: 61 DGIEATRLVKENYPDLKVIILTTFNEDEFIFDVLKNGADGYVLKDAGSKEIFNSIKAACE 120 Query: 121 GNILLNPKITREVVNALNSVNNAGTENLRNEQILQLLTPRELEVAKCIMEGKSNKEISSD 180 G++LLNP++T ++VNALN+++ + L+ + +L LLTPRE++VA +++GKSN+ I+ Sbjct: 121 GSVLLNPQVTLKLVNALNTLDK--KKPLQEKNLLHLLTPREMDVANHVLKGKSNRAIAEA 178 Query: 181 LFITEGTVKNYVSRMLEKLELKNRTELTLCLQKSL 215 LF+TEGT+KNYVS++LEKLEL NR+EL L LQ L Sbjct: 179 LFLTEGTIKNYVSKILEKLELGNRSELILYLQNYL 213 >ref|NP_348871.1| Response regulator (CheY-like receiver domain and HTH-type DNA-binding domain) [Clostridium acetobutylicum] pir||H97177 response regulator (CheY-like receiver domain and HTH-type DNA-binding domain) [imported] - Clostridium acetobutylicum gb|AAK80211.1| Response regulator (CheY-like receiver domain and HTH-type DNA-binding domain) [Clostridium acetobutylicum] Length = 213 Score = 211 bits (538), Expect = 7e-54, Method: Compositional matrix adjust. Identities = 109/207 (52%), Positives = 150/207 (72%), Gaps = 3/207 (1%) Query: 1 MVDIMIVDDQQIVREGLKMILSLHEEINVIGEASNGEEALELLSYTSPEVILMDIKMPVM 60 M+ +MI DDQ IVREGLK ILSL +EI VI EA +G + + L ++ILMD++MP M Sbjct: 1 MIRVMIADDQVIVREGLKKILSLDDEIEVICEAEDGYDVINKLREHIVDIILMDVRMPKM 60 Query: 61 NGIEATKLVKAKYPGIKVIILTTFNDSEYIFTGLKNGADGYILKDSGSQEIISSIKTACE 120 +GI+ T LVK +YP I +IILTTF++ EYIF G+K+G GY+LKDS I+ S+K A Sbjct: 61 DGIKTTNLVKKQYPKINIIILTTFDEDEYIFNGIKSGISGYLLKDSEIDYILKSVKEAYN 120 Query: 121 GNILLNPKITREVVNALNSVNNAGTENLRNEQILQLLTPRELEVAKCIMEGKSNKEISSD 180 ++ +P +T ++VNALN NN N N++IL +LT RE+E+ K + GKSNKEIS Sbjct: 121 NKMMFDPVVTPKLVNALNLSNNI---NSTNKEILSVLTEREMEITKLVTSGKSNKEISET 177 Query: 181 LFITEGTVKNYVSRMLEKLELKNRTEL 207 LFI+EGTVKNY+S++L+KL+L+ RT+L Sbjct: 178 LFISEGTVKNYISKILKKLKLQRRTQL 204 >ref|NP_965466.1| two-component system response regulator [Lactobacillus johnsonii NCC 533] gb|AAS09432.1| two-component system response regulator [Lactobacillus johnsonii NCC 533] Length = 224 Score = 191 bits (486), Expect = 7e-48, Method: Compositional matrix adjust. Identities = 92/210 (43%), Positives = 142/210 (67%) Query: 1 MVDIMIVDDQQIVREGLKMILSLHEEINVIGEASNGEEALELLSYTSPEVILMDIKMPVM 60 M+ I+I DDQQ++R+ +K+IL +++ +V +NG+EAL + P+VILMD++MPVM Sbjct: 1 MIKILIADDQQLIRDSIKIILESNDDFSVTDTVANGKEALNSIEKNKPDVILMDVRMPVM 60 Query: 61 NGIEATKLVKAKYPGIKVIILTTFNDSEYIFTGLKNGADGYILKDSGSQEIISSIKTACE 120 +G TK VK KYP IKVIILTTF+D ++IF+ LK GA GY+LK ++ ++I+T + Sbjct: 61 DGTVCTKYVKEKYPDIKVIILTTFDDDDFIFSALKYGASGYLLKGGSPADLFTAIRTVAQ 120 Query: 121 GNILLNPKITREVVNALNSVNNAGTENLRNEQILQLLTPRELEVAKCIMEGKSNKEISSD 180 G ++NP IT +V + + A N+Q + + E V + + G SNKEIS+ Sbjct: 121 GGAMINPDITEKVFRLFSKMAQANYTISVNDQETKDFSKSEWCVIQQVGLGLSNKEISTK 180 Query: 181 LFITEGTVKNYVSRMLEKLELKNRTELTLC 210 LF++EGTV+NY+S++LEKL L++RT+L + Sbjct: 181 LFLSEGTVRNYISKILEKLNLRDRTQLAIW 210 >ref|ZP_00109115.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Nostoc punctiforme] Length = 215 Score = 189 bits (480), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 89/209 (42%), Positives = 141/209 (67%), Gaps = 4/209 (1%) Query: 1 MVDIMIVDDQQIVREGLKMILSLHEEINVIGEASNGEEALELLSYTSPEVILMDIKMPVM 60 M+ I++VDDQ ++R+GLK +L + EI VIGEA NG+ ALE + P+++LMD++MPVM Sbjct: 1 MIQILLVDDQHLIRQGLKSMLESNAEIQVIGEAENGQRALEQIPALQPDIVLMDVRMPVM 60 Query: 61 NGIEATKLVKAKYPGIKVIILTTFNDSEYIFTGLKNGADGYILKDSGSQEIISSIKTACE 120 +G+ TK + +YP +KV++LTTF+D EY+F ++ GA GY+LKD+ E++ +I++ + Sbjct: 61 DGVATTKAIAQQYPDVKVLVLTTFDDDEYVFQAMRVGAKGYLLKDTEPDELMLAIRSVYK 120 Query: 121 GNILLNPKITREVVNALNSVNNAGTENLRNEQILQLLTPRELEVAKCIMEGKSNKEISSD 180 G LL P + + AL + ++ Q LTPREL+V + I G +N+EI+ Sbjct: 121 GQTLLGPGLFEK---ALIPIPVPVPSVEPPPELAQ-LTPRELDVLRLIASGANNREIAES 176 Query: 181 LFITEGTVKNYVSRMLEKLELKNRTELTL 209 LF++E TVKNYV+ +L +L L++RT+ L Sbjct: 177 LFLSENTVKNYVTNILSRLSLRDRTQAAL 205 >ref|NP_346881.1| Response regulator (CheY-like recever domain and HTH DNA-binding domain) [Clostridium acetobutylicum] pir||B96929 response regulator (CheY-like recever domain and HTH DNA-binding domain) [imported] - Clostridium acetobutylicum gb|AAK78221.1| Response regulator (CheY-like recever domain and HTH DNA-binding domain) [Clostridium acetobutylicum] Length = 208 Score = 188 bits (478), Expect = 6e-47, Method: Compositional matrix adjust. Identities = 93/212 (43%), Positives = 141/212 (66%), Gaps = 8/212 (3%) Query: 4 IMIVDDQQIVREGLKMILSLHEEINVIGEASNGEEALELLSYTSPEVILMDIKMPVMNGI 63 ++IVDD ++RE L ++L L +EI +IG +NG+EA + P+++LMDI+MP+M+G+ Sbjct: 3 VLIVDDDALIRESLSILLDLEDEIEIIGTCANGQEAFDFCKNNRPDIVLMDIRMPIMDGV 62 Query: 64 EATKLVKAKYPGIKVIILTTFNDSEYIFTGLKNGADGYILKDSGSQEIISSIKTACEGNI 123 TK++K + IKV+ILTTF D EYI LKNGA+GYILK+ S II S+K GN+ Sbjct: 63 LGTKVIKESFKDIKVVILTTFKDDEYIKEALKNGAEGYILKNQSSDSIIDSLKAVVNGNM 122 Query: 124 LLNPKITREVVNALN-SVNNAGTENLRNEQILQLLTPRELEVAKCIMEGKSNKEISSDLF 182 + + + + N + +N G E LT RE+EV + I +G SNKEI+S L+ Sbjct: 123 VFEQNVAKTISNFIKEDKSNNGLEQYN-------LTEREMEVLRNIGDGLSNKEIASKLY 175 Query: 183 ITEGTVKNYVSRMLEKLELKNRTELTLCLQKS 214 ++EGTV+NY++ +LEKLEL++RT+L + K+ Sbjct: 176 LSEGTVRNYITSLLEKLELRDRTQLAIFYLKN 207 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.314 0.133 0.353 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 289,608,306 Number of extensions: 11265412 Number of successful extensions: 41681 Number of sequences better than 1.0e-05: 3149 Number of HSP's gapped: 42210 Number of HSP's successfully gapped: 3152 Length of query: 215 Length of database: 757,237,578 Length adjustment: 121 Effective length of query: 94 Effective length of database: 428,710,599 Effective search space: 40298796306 Effective search space used: 40298796306 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 123 (52.0 bits)