BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0028.p (2184 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_486686.1| polyketide synthase type I [Nostoc sp. PCC 7120... 691 0.0 ref|ZP_00110270.1| COG3321: Polyketide synthase modules and rela... 572 e-161 gb|AAR87760.1| putative peptide synthetase/polyketide synthase [... 569 e-160 ref|ZP_00110267.1| COG3321: Polyketide synthase modules and rela... 568 e-160 gb|AAF15892.2| NosB [Nostoc sp. GSV224] 567 e-159 >ref|NP_486686.1| polyketide synthase type I [Nostoc sp. PCC 7120] pir||AG2136 polyketide synthase type I [imported] - Nostoc sp. (strain PCC 7120) dbj|BAB74345.1| polyketide synthase type I [Nostoc sp. PCC 7120] Length = 1488 Score = 691 bits (1784), Expect = 0.0, Method: Compositional matrix adjust. Identities = 415/1139 (36%), Positives = 603/1139 (52%), Gaps = 138/1139 (12%) Query: 4 NTRTGLEVAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGVPAEVYTKENF 63 N TGLE+AIIG++G FPGA NLE+++QN++NGV+SI+ TDEQ+ + GV N+ Sbjct: 2 NNPTGLEIAIIGINGKFPGANNLEEYWQNLRNGVESITNLTDEQIQKNGVDPTQLKHPNY 61 Query: 64 VKAKGYLNECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAIGVY 123 VK + ++ EYFD FFG+ P EA+ +DPQ RL E AW ALEDAGY P AIGVY Sbjct: 62 VKRQAIIDNIEYFDAEFFGFNPREAEILDPQHRLFLECAWTALEDAGYNPENYTGAIGVY 121 Query: 124 AGGRPHFHWEALSLSMGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFTACSTS 183 AG + + L + +N +++ NDKD ++TRVSYKLNL+GPS + TACSTS Sbjct: 122 AGAAMNNYLLNLITNPQIQNQISRYQLFLSNDKDFLTTRVSYKLNLRGPSLDIQTACSTS 181 Query: 184 LVAVHAACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAASDGTVV 243 LVAVH ACQ ++SGECD+A+AGGVS+ GY +Q+G I S DG CRAFDA + GT+ Sbjct: 182 LVAVHVACQSLLSGECDIALAGGVSLAKA--TGYLYQEGGIYSPDGHCRAFDADAQGTIA 239 Query: 244 GNGIGLVILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRTAHRVA 303 G+G+G+V+LKRL++A++D D+I+AVIKG+AINNDG KV Y+AP +D QA VIR A +A Sbjct: 240 GSGLGIVVLKRLQEAIEDRDYIHAVIKGSAINNDGGLKVSYTAPRIDTQAAVIRAAQALA 299 Query: 304 GVDPKEIGYIEAHGTGTALGDPIEVKALTTAFQ--TKRKHFCGLGSVKTNIGHLDSAAGI 361 GV+P +I YIE HGTGTALGDPIE+ ALT AF+ T++ FC + SVKTNIGHLD+AAGI Sbjct: 300 GVEPADISYIETHGTGTALGDPIEIAALTQAFRAGTEKTGFCAISSVKTNIGHLDAAAGI 359 Query: 362 AGLIKAVLALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWENGSGPRRAGVSSFGV 421 A LIK VLAL ++ + P LHF PNP + +PFY+ + +WE PRRAGVSSFG+ Sbjct: 360 ASLIKTVLALKHQQIPPNLHFQQPNPQIDFSQTPFYVNTNLVDWETDKTPRRAGVSSFGI 419 Query: 422 GGTNAHIVLEEAPSGQSVKQAEAQ--EQLLVFSAKTREALEQSIEAFVQDVQKNPGKASA 479 GGTNAH++LEEAP ++ ++ + Q+L SAK+ +ALE++ +Q++P A Sbjct: 420 GGTNAHVILEEAPIKFKIQNSKFKINYQMLCLSAKSEKALEEATINLATYLQQHPQFNLA 479 Query: 480 DIAYTLQQGREHFSYRQYVSCRTLLAGCAALRVKADQALWVDPKKELKP-VYFWFAGMA- 537 DIAYTL GR+HF+YR+ V C+T A ++ + + E P + F F G Sbjct: 480 DIAYTLHIGRQHFAYRRMVLCQT---TEEAAQILEKETKYTHTNSEKSPSIAFMFPGQGS 536 Query: 538 ---------------LEEAVQHYHSCLHHPYCREEMEELLLQASGIRGVKRDELLSGGSD 582 E + H L H ++ +L + I + Sbjct: 537 HYLNMGKELYETEAIFREQIDHCCELLQHDLGL-DLLSILFETESIPSPQSPVPSPQSQT 595 Query: 583 VYIGQTPVFLFQLALAKWLLRVGVKPAALMGTGTGAYVAGCLAGVFTLEEALMLMEKRDR 642 +Y Q +F+ + ALAK + G++P A++G G YV LAGVF+L + L L+ R R Sbjct: 596 IY-AQPALFIIEYALAKLWISWGIQPQAMIGHSLGEYVVATLAGVFSLPDVLKLVALRGR 654 Query: 643 LLEEW------------------------------------RGSEGDLFLLE-------- 658 L+++ G+E ++ LE Sbjct: 655 LMQQCPTGAMLSVGMSAAKLQPLLTDNLVIAAYNAPELCVVSGTEAEIVQLETNLNKQGI 714 Query: 659 -----------------ALQSEFYEAFDSVTLSAPAIPLLSADAGS-NTVLDVTLPDYWV 700 ++ + F AF +TL P IP +S G+ T T P YWV Sbjct: 715 SNRRLQTSHAFHSPLMESMITPFIAAFQKITLQTPKIPFISNVTGTWITAEQATDPHYWV 774 Query: 701 NALGADDDGKSLPAKAEEADKHLVLHFGA-------AGEPSGPSGYISLVKSGPE----- 748 N L + + + ++L GA A + + +S ++ + Sbjct: 775 NHLRQPVQFATGIKELLTEPQQILLEVGAGRTLATLAKQQTNSHTILSSLRHPQDTQSDV 834 Query: 749 --LLETVGCIWANGYPLQWDELAKHQNRARVILPTYPFTRKRYWVDTQQIKQFQNIWKRQ 806 LL+T+G +W G + W+ HQ R R+ LPTYPF R+RYW+D + +Q Sbjct: 835 AFLLQTLGQLWLAGVSIDWENFYTHQQRQRLPLPTYPFQRQRYWIDLKAGEQ-------- 886 Query: 807 EPQPGKEN-KEEWMYVPSWIRSEYMPEEREQQQGLI-AVFATQEPFVARCIERLEQMGHT 864 G EN +Y+PSW RS P+ ++ L VF I L+ +GH Sbjct: 887 ----GSENIPSPRLYLPSWERSLPHPQVDIAEKRLCWLVFTDNYGIYQEIINTLQAVGHD 942 Query: 865 IARIEAGESFQQNNL-SFEINPEXXXXXXXXXXXXXXXGDGPVRIVHFWCMHPQSAAREQ 923 + + GE + Q +F +NP+ P I++ W + +Q Sbjct: 943 VIIVSQGEKYDQPAYRTFTVNPQNSQDFVELWSDLELRELIPHHILYLWDL----TDLQQ 998 Query: 924 LPEAEECNRLGYYTLLNIARAVSQLQLQQPVTIDIVANQVAEVTGNETVVPAKATLFGPL 983 P +LL +A+A+S +++ +T+ +V N + GNE + P KAT++G Sbjct: 999 QP----------LSLLYLAQAISSQSIEREITLTLVTNDGQLLLGNENIQPMKATVWGMG 1048 Query: 984 RVIPKEYENIACRLIDTD-----QYDHHILCRILSGPENNRRADWIALRNNYIWEPAFK 1037 +VI +E + CR +D + I ++++ NN+ +A R NY W +K Sbjct: 1049 KVISQEIPQLTCRCVDISLSTVASTNEQIAQQLITECLNNQNDSVVAYRGNYRWNQIYK 1107 >ref|ZP_00110270.1| COG3321: Polyketide synthase modules and related proteins [Nostoc punctiforme] Length = 1959 Score = 572 bits (1474), Expect = e-161, Method: Compositional matrix adjust. Identities = 326/706 (46%), Positives = 452/706 (64%), Gaps = 21/706 (2%) Query: 6 RTGLEVAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGVPAEVYTKENFVK 65 +TG E+AIIG++G FPGAKN ++F+QN++ GV+SIS FTDE+L +G+ A FVK Sbjct: 10 KTGSEIAIIGIAGKFPGAKNTDEFWQNLQRGVESISVFTDEELLASGIDAATLKNPKFVK 69 Query: 66 AKGYLNECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAIGVYAG 125 A+ L + E FD SFFG+ P EA DPQ RL E A++ALEDAGY Q +IGVYAG Sbjct: 70 ARAVLEDVELFDASFFGFNPREADITDPQHRLFLECAYIALEDAGYDSENYQGSIGVYAG 129 Query: 126 GRPHFHWEALSLSMGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFTACSTSLV 185 + + L+ + ++A DKD ++TRVSYKLNL+GPSYT+ TACSTSLV Sbjct: 130 ASFSGYLLNVYLNEDIIKSIDYHQLAIAGDKDYLTTRVSYKLNLEGPSYTVQTACSTSLV 189 Query: 186 AVHAACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAASDGTVVGN 245 AVH A Q +++GECDMA+AGGVS+ S + GY +++G I S DG CRAFDA + GTV G Sbjct: 190 AVHLAAQSLLNGECDMALAGGVSINSSGKTGYLYKEGGIGSPDGHCRAFDAQAQGTVGGE 249 Query: 246 GIGLVILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRTAHRVAGV 305 G+G+V+LKRL+DAL D D I+A+IKG+A+NNDGS KV Y+AP +DGQA+VIRTA VA V Sbjct: 250 GVGIVVLKRLDDALADGDTIHAIIKGSAVNNDGSFKVSYTAPRIDGQAKVIRTAQVVAEV 309 Query: 306 DPKEIGYIEAHGTGTALGDPIEVKALTTAFQ--TKRKHFCGLGSVKTNIGHLDSAAGIAG 363 +P+ I YIEAHGTGT+LGDPIE+ ALT AF+ T++K FC +GSVKTNIGHLD+AAG+ G Sbjct: 310 EPETITYIEAHGTGTSLGDPIEIAALTQAFRATTEKKGFCAIGSVKTNIGHLDAAAGVTG 369 Query: 364 LIKAVLALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWENGSGPRRAGVSSFGVGG 423 LIK VLAL ++ + P+LHF PNP + +SPFY+ + EW PRRAGVSSFG+GG Sbjct: 370 LIKTVLALKHQQIPPSLHFQQPNPQIDFANSPFYVNTTLTEWTTNGIPRRAGVSSFGIGG 429 Query: 424 TNAHIVLEEAPSGQSVKQAEAQE----QLLVFSAKTREALEQSIEAFVQDVQKNPGKASA 479 TNAH++LEEAP+ + + ++ LLV SAKT ALE + ++++P A Sbjct: 430 TNAHVILEEAPAKEQGSRGAGEQGRKYHLLVLSAKTESALETATANLANHLKQHPNLNLA 489 Query: 480 DIAYTLQQGREHFSYRQYVSCRTLLAGCAALRVKADQALWVDPKKEL-KPVYFWFAGMA- 537 D+A+TL GR F +R+ V C+ + L Q ++ ++ +PV F F+G Sbjct: 490 DVAHTLGIGRRAFDHRRIVVCQDMNDAVKVLSTSDSQRVFTHYQQPCHRPVVFMFSGQGT 549 Query: 538 --LEEAVQHYHSCLHHPYCREEMEELLLQASG--IRGVKR-DELLSGGSDVYIGQTPV-- 590 + A + Y S + ELL G +R V DE + + + + QT V Sbjct: 550 QYVNMARELYGSEPIFTLTVDSCCELLQPHLGFDLRHVLYPDEAQNAKATLELQQTSVAQ 609 Query: 591 ---FLFQLALAKWLLRVGVKPAALMGTGTGAYVAGCLAGVFTLEEALMLMEKRDRLLEEW 647 F+ + ALA+ + GV+P A++G G YVA LAGVF+LE+ALML+ R RL+++ Sbjct: 610 PALFVIEYALAQLWMAWGVQPEAMIGHSIGEYVAATLAGVFSLEDALMLVAIRGRLIQQL 669 Query: 648 RGSEGDLFLLEALQSEFYEAFDS-VTLSAPAIPLLSADAGSNTVLD 692 G++ ++ + E DS ++L+A P +G+ ++ Sbjct: 670 --PTGEMLSVQLPEQEVQPLLDSQLSLAASNGPSYCVVSGATEAIN 713 Score = 198 bits (504), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 141/496 (28%), Positives = 230/496 (46%), Gaps = 46/496 (9%) Query: 797 KQFQNIWKRQEPQPGKENKEEWMYVPSWIRSEYMPEEREQ------QQGLIAVFATQEPF 850 +Q+Q++ + K + +W Y+PSW R+ MP + Q Q G VF + Sbjct: 1297 EQYQDLLSK------KPDIADWFYIPSWKRT--MPPQPFQPGFGITQPGCWLVFVDEFGL 1348 Query: 851 VARCIERLEQMGHTIARIEAGESFQQNN----LSFEINPEXXXXXXXXXXXXXXXGDGPV 906 R +++L + ++ GE FQQ++ ++ INPE G P Sbjct: 1349 GERLVKQLVLENQDVITVKVGEQFQQSSEYSQYTYTINPEKEDDYNTLLKGLRTLGKIPR 1408 Query: 907 RIVHFWCMHPQSAAREQLPEAEECNRLGYYTLLNIARAVS---------QLQLQQPVTID 957 RIVH W + S + LG+ +LL + +A+S + V I Sbjct: 1409 RIVHLWSVTSNSYTNSAI------EALGWSSLLFLGQAMSDDKALRVYAENNQTDAVEIA 1462 Query: 958 IVANQVAEVTGNETVVPAKATLFGPLRVIPKEYENIACRLID-----TDQYDHHILCRIL 1012 IV+N + EVTG+E + P KA + G +V+P EY NI CR ID ++ + ++ ++ Sbjct: 1463 IVSNNLQEVTGSEMLCPEKALVLGACKVMPLEYANINCRSIDVVIPESESGEEQLIKALI 1522 Query: 1013 SGPENNRRADWIALRNNYIWEPAFKQVRLTTPLHAVHKRLTSXXXXXXXXXXXXXXXHVA 1072 + IA R W F+ V+L + L +A Sbjct: 1523 AELTTYTSDQVIAYRGRNRWVQDFEPVQLHGTVAG--NLLREQGVYLITGGLGGVGLLLA 1580 Query: 1073 KYLAEQYQAQVVLLNRSQFLPEAEWDKWYAIHSGDDPVSQKIASLREIKAAASGFYLVQA 1132 +YLA+ QA+++LL RS F + +W +W + H D +SQKI L+ +K + +V Sbjct: 1581 EYLAQTVQAKLILLGRSAFPDQDKWSEWLSTHDRHDSISQKIQKLQAMKTLGAEVMVVST 1640 Query: 1133 DITDAAQVRAVFGQILERCGAINGIIQAAGVPDGAVIQRRSREMCEAVFGTKIYGTQVLQ 1192 D+T+ Q+ AV + +R G I+G+I AA V G ++Q ++E + K+ GT+VL+ Sbjct: 1641 DVTNLEQMSAVLKKANQRFGEIHGVIHAAAVYGGGMMQLATKETVASAIAPKVQGTRVLE 1700 Query: 1193 KVIGELSRPVDXXXXXXXXXXXXAPPAQVAYSAANSFLDAFAQINTKR---GYFTQAINW 1249 + E +D V Y+AAN+FLD+FAQ + + F ++INW Sbjct: 1701 TLFQE--SKLDFFVLCSSLSSFAGTSGMVDYTAANAFLDSFAQYSAAKYGTWKFIKSINW 1758 Query: 1250 DRWENTGMTGLPAQSR 1265 DRW N GM +P ++R Sbjct: 1759 DRWNNVGM-AVPVEAR 1773 >gb|AAR87760.1| putative peptide synthetase/polyketide synthase [Bacillus cereus] Length = 2562 Score = 569 bits (1467), Expect = e-160, Method: Compositional matrix adjust. Identities = 303/647 (46%), Positives = 404/647 (62%), Gaps = 21/647 (3%) Query: 10 EVAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGVPAEVYTKENFVKAKGY 69 +VA++GM+ PGA NL+QF+ N++ G++SI FTDE+L+E G+P EV K N++K+KGY Sbjct: 1038 DVAVVGMAVRMPGASNLKQFWSNLEQGIESIRTFTDEELSEMGIPKEVIQKPNYIKSKGY 1097 Query: 70 LNECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAIGVYAGGRPH 129 L + + FDN FF Y+ EA+ MDPQ R+LHE AW ALE AG + GVY GG P+ Sbjct: 1098 LEDVDAFDNEFFDYSLKEAEMMDPQLRILHECAWEALEQAG-EVNSSHMNTGVYVGGSPN 1156 Query: 130 FHWEALSLSMGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFTACSTSLVAVHA 189 FHW S++ S N EDF+ LN+KD +TR++YKLNLKGP+ T+ TACSTSLVA+ Sbjct: 1157 FHW-LRSIASESSNTLEDFQAMLLNEKDFFATRLAYKLNLKGPAITVQTACSTSLVAIQN 1215 Query: 190 ACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAASDGTVVGNGIGL 249 A +I G CD+A+AGGVS+T P + GY ++DGMI S DG CRAFD + GTV GNG G+ Sbjct: 1216 AWADLIDGRCDIALAGGVSITYPTKTGYLYEDGMIFSPDGHCRAFDKDAQGTVGGNGAGI 1275 Query: 250 VILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRTAHRVAGVDPKE 309 V+LKRLEDAL D + I+ VIKG A+NNDGS K G++AP VDGQA VI++AH +AGV P+E Sbjct: 1276 VVLKRLEDALRDGNLIHGVIKGAAVNNDGSNKAGFTAPGVDGQAAVIKSAHEIAGVKPEE 1335 Query: 310 IGYIEAHGTGTALGDPIEVKALTTAFQTKRKHFCGLGSVKTNIGHLDSAAGIAGLIKAVL 369 I YIE HGTGT LGDPIEV+AL AF + +GSVKTNIGHLD+AAG+ G IK VL Sbjct: 1336 ISYIETHGTGTQLGDPIEVEALKLAFGKQEPGRVLIGSVKTNIGHLDAAAGVGGFIKTVL 1395 Query: 370 ALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWENGSGPRRAGVSSFGVGGTNAHIV 429 AL NK + P+LH+ NPNP + +PF + + W+ RRAGVSSFG+GGTNAHIV Sbjct: 1396 ALKNKKIPPSLHYNNPNPSIDFGKNPFRVNTELIPWKEEV--RRAGVSSFGMGGTNAHIV 1453 Query: 430 LEEAPSGQSVKQAEAQE-QLLVFSAKTREALEQSIEAFVQDVQKNPGKASADIAYTLQQG 488 LE P + K E Q LL SAKT E+L+++ + +++NP + +D AYTLQ+G Sbjct: 1454 LESVPD--NAKNFEKQSWNLLTVSAKTEESLDKATNDLLLYLKENPEISLSDTAYTLQKG 1511 Query: 489 REHFSYRQYVSCRTLLAGCAALRVKADQALWVDPKKELKPVYFWFAGMALEEAVQHYHSC 548 R F YR V + L D L E +P+ F F+G + Sbjct: 1512 RREFPYRTAVVANGIEDAIEKL---VDTGLEKTNAMESRPLAFLFSGQGSQYINMGRDLY 1568 Query: 549 LHHPYCREEMEELLLQASGIRGVKRDELLSGGSD-----------VYIGQTPVFLFQLAL 597 + P RE +++ L S + +L + + Q +F + AL Sbjct: 1569 ENEPVFREHVDQGLALLSNWLDIDMKNILYPTKETEDKATEQLNRTSMTQPLLFTIEYAL 1628 Query: 598 AKWLLRVGVKPAALMGTGTGAYVAGCLAGVFTLEEALMLMEKRDRLL 644 AK L+ GV P + G G +VA CLA V + E+AL L+ R +L+ Sbjct: 1629 AKLLMNWGVYPRVMFGHSIGEFVAACLAEVMSYEDALHLVMIRGKLM 1675 Score = 191 bits (485), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 155/636 (24%), Positives = 276/636 (43%), Gaps = 44/636 (6%) Query: 656 LLEALQSEFYEAFDSVTLSAPAIPLLSADAGSN-TVLDVTLPDYWVNALGADDDGKSLPA 714 +++ + F +A ++ LS+P IP +S G T T P YW L + + Sbjct: 1748 MMDEVLDAFEQAVGNIKLSSPKIPYISNVTGEMITANQATSPSYWAQHLRSTVQFSKGLS 1807 Query: 715 KAEEADKHLVLHFGAAGEPSGPSGYI------------------SLVKSG--PELLETVG 754 + + L G + S ++ L KS L + +G Sbjct: 1808 EIFHLKNVICLEIGPG---NALSTFVLKHLNRSKDQLALNMLRHPLDKSNDLEHLCKQIG 1864 Query: 755 CIWANGYPLQWDELAKHQNRARVILPTYPFTRKRYWVDTQQIKQFQNIWKRQEPQPGKEN 814 +W G + W+ +N+ + LPTYPF +KR+ D Q Q++ + + N Sbjct: 1865 RLWMQGGTIDWNTFNNSENKRLLDLPTYPFMKKRFKADPFFNTQSQSLTQETRGHNKQAN 1924 Query: 815 KEEWMYVPSWIRSEYMP-EEREQQQGLIAVFATQEPFVARCIERLEQMGHTIARIEAGES 873 ++W Y+PSW R + +++Q+ +F R IE+L++ GH + ++ G Sbjct: 1925 IKDWFYLPSWERKTLKSIQIKKEQKYKWLIFNDHLNRFNRLIEKLKREGHDVIEVKTGGI 1984 Query: 874 F-QQNNLSFEINPEXXXXXXXXXXXXXXXGDGPVRIVHFWCMHPQSAAREQLPEAEECNR 932 F ++++ + I P P +I+H W +P + E Sbjct: 1985 FSEKSDGLYTICPSQKMHYEMLFSELEQKDLLPNKIIHAWSFNPVNEVILDQERIERSMN 2044 Query: 933 LGYYTLLNIARAVSQLQLQQPVTIDIVANQVAEVTGNE-TVVPAKATLFGPLRVIPKEYE 991 GYY+LL IA+A+ ++ + + ++I +++ EVTG E + P +AT+ G ++ E++ Sbjct: 2045 EGYYSLLYIAQAIGKINYEGALQLNIFTDRMFEVTGTELNLKPEQATILGFSKICNLEFQ 2104 Query: 992 NIACRLIDTDQYDHHILCRI-LSGPENNRRADWIALRNNYIWEPAFKQVRLTTPLHAVH- 1049 NI CR ID D + L + +A R + W Q + +P Sbjct: 2105 NIKCRTIDMDTDSQQMFEEAGLMESFVDSTDIVVAYRGRHRW----AQTIIQSPFEEEDV 2160 Query: 1050 --KRLTSXXXXXXXXXXXXXXXHVAKYLAEQY-QAQVVLLNRSQFLPEAEWDKWYAIHSG 1106 RL +AK LA + +++L+ RS+F P +W+++ + + Sbjct: 2161 EIDRLRESGVYLITGGLGGIGFEIAKDLANRVPNVKLILIGRSEFPPRNQWEQY--LENK 2218 Query: 1107 DDPVSQKIASLREIKAAASGFYLVQADITDAAQVRAVFGQILERCGAINGIIQAAGVPDG 1166 D+ VS+ I+ L +++ + + ++ AD+++ ++ + R G+ING+I AAGV D Sbjct: 2219 DERVSRVISDLLTMESQGAEYMILSADVSNQDDMKQAIEKAKSRFGSINGVIHAAGVADY 2278 Query: 1167 -AVIQRRSREMCEAVFGTKIYGTQVLQKVIGELSRPVD--XXXXXXXXXXXXAPPAQVAY 1223 ++ R +E + KI GT VL ++ + P+D Q Y Sbjct: 2279 LGIMMNREKESNNKILAPKIKGTLVLDALLKD--EPIDFFVLCSSIGNVAYHMKFGQSGY 2336 Query: 1224 SAANSFLDAFAQINTKR-GYFTQAINWDRWENTGMT 1258 +AAN FLDAFA G FT AI W W+ GM+ Sbjct: 2337 NAANEFLDAFAFYKRAHDGVFTVAITWPDWQEVGMS 2372 Score = 67.8 bits (164), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 93/435 (21%), Positives = 186/435 (42%), Gaps = 44/435 (10%) Query: 1743 LSSAQKRLYFQQQLQPDSVAYNILEITSVEGNLDPGKLQNAFDLLIQRHAVLRTSFDVIN 1802 L+ Q+ + + +P+ Y+ + G ++ K + A++ + + + +LRT F Sbjct: 18 LTPVQEGILYHYLKEPEGKLYHEELRLCLTGKINIPKFEEAWNYVTRENEMLRTIFRW-- 75 Query: 1803 GEIVQIIHDRAEFQVEHVTVKXXXXXXXXXXFMQPFDLRSAPLLRVKIVRCGMQKYVWLF 1862 + + + ++ T + FDL++ P +++ +Y + Sbjct: 76 ----EKVKQPVQLILKEHTPNIIYSDGKVSNDTESFDLQTVPF-SIELCHLNEGEYEMVL 130 Query: 1863 DIHHIIADNLSVEILKSELISIYNGQADQLKPILL---EYVDFVGWQNEQIRRGKFDKQT 1919 HHI+ D S I+ E I +Y P + ++ +++ WQ +Q + + Sbjct: 131 RHHHILFDGWSNSIILQEFIKVYRELIKGDVPSSINKKKFKEYILWQQKQDKSKQKLFWE 190 Query: 1920 EYWLQQLSGELPESRLPADYPRPAVLSHQGDIYTFTLDETVTGRLKQGMKRNTTTLFMNM 1979 +Y L +L+ ++ S ++ + A Y +D+ + R + TL Sbjct: 191 QY-LNELTEQINLSNKNSNQLKKA------KTYVKEIDKERSDRFRSFASNQGVTLATLF 243 Query: 1980 MALFSVLLQKYTGQDEVMIGASLAGRN---HADLADMVGMFANVLPFRSRINRDGSFEQL 2036 + +LLQ+Y ++V+ G +++GR+ H L++MVG+F N P R + + L Sbjct: 244 YTAWGLLLQRYKNSEDVIFGTTVSGRSIPMHG-LSEMVGLFINTPPLRVSADGRMTVSDL 302 Query: 2037 LTEVKTQSLQIFENQDVQFEVLVEALGRSHQLSENPLFNVMLVLP----DVAPAEAAMDQ 2092 L +++ DVQ E + + N F+ ++V+ D+ + + Sbjct: 303 LQRIQS---------DVQRRTEYET---TPIVDLNVSFDTIMVVENYPLDIEKLKEIDES 350 Query: 2093 VRLQAYPFCNPSSKFDLTLWVYDYDDSIEMRMEYSTDLFARKTIITMCRH---LLDIASL 2149 VR+ Y N + +DLT+ + + DSI++ M + D+F II + H LLD L Sbjct: 351 VRISGYE-VNEMTNYDLTVSIECF-DSIKLAMMWPEDVFDESIIIGITNHFIQLLDSMLL 408 Query: 2150 VAGNPDILIKEIMLD 2164 G P +K MLD Sbjct: 409 DEGQPIQTLK--MLD 421 >ref|ZP_00110267.1| COG3321: Polyketide synthase modules and related proteins [Nostoc punctiforme] Length = 968 Score = 568 bits (1463), Expect = e-160, Method: Compositional matrix adjust. Identities = 306/673 (45%), Positives = 427/673 (63%), Gaps = 29/673 (4%) Query: 1 MKENTRTGLEVAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGVPAEVYTK 60 +++N L++AIIGMSG FP AKNL+ F+QN++ G++SISFF++++L GV Sbjct: 6 LQQNQIGDLDIAIIGMSGRFPQAKNLDIFWQNLQKGLESISFFSNQELEALGVDPTTLND 65 Query: 61 ENFVKAKGYLNECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAI 120 N+VKA L + E FD SFF Y+P A+ +DPQ RL E AW ALE AGY + I Sbjct: 66 PNYVKANAVLEDIELFDASFFDYSPKTAEIIDPQHRLFLETAWEALESAGYDSKTYKGRI 125 Query: 121 GVY--AGGRPHFHWEALSLSMGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFT 178 VY A +F + S S + D +I H N D ++TRV+YKL+LKG + T+ T Sbjct: 126 SVYGSASISSYFLFNLFSNSELIKLVGLD-QIRHHNRTDNLTTRVAYKLDLKGSAITIQT 184 Query: 179 ACSTSLVAVHAACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAAS 238 CS+SLVAVH ACQ +I ECD+ +AGGVSVT+ + GY +Q+G ILS DG CRAFDA + Sbjct: 185 GCSSSLVAVHLACQSLIDRECDLVLAGGVSVTTLQKTGYSYQEGGILSPDGHCRAFDAKA 244 Query: 239 DGTVVGNGIGLVILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRT 298 GTV GNG+G+VILKRL DA+ D D+I+AVIKG+AINNDGS K+GY+APS+DGQA+VI Sbjct: 245 QGTVGGNGVGIVILKRLADAIADGDYIHAVIKGSAINNDGSAKIGYTAPSIDGQAKVIAE 304 Query: 299 AHRVAGVDPKEIGYIEAHGTGTALGDPIEVKALTTAF--QTKRKHFCGLGSVKTNIGHLD 356 A ++ ++P + Y+EAHGTGT LGDPIE+ ALT +F +T++K+FC +GSVKTNIGHLD Sbjct: 305 ALAISRIEPDMVSYVEAHGTGTVLGDPIEIAALTKSFRARTQKKNFCAIGSVKTNIGHLD 364 Query: 357 SAAGIAGLIKAVLALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWENGSGPRRAGV 416 +A+G+A LIK VLAL +K + P+LHF PNP + ++PFY+ D++ EW++ PRRAGV Sbjct: 365 TASGVASLIKTVLALKHKQIPPSLHFEQPNPQIDFANNPFYVNDKLSEWKSNGHPRRAGV 424 Query: 417 SSFGVGGTNAHIVLEEAPSGQSVKQAEA----------QEQLLVFSAKTREALEQSIEAF 466 SSFG+GGTNAH++LEEAP + + + QLLV SAKT AL+ + Sbjct: 425 SSFGIGGTNAHVILEEAPVREQGEHTSTTLSNRGRQGRKYQLLVLSAKTESALQAATANL 484 Query: 467 VQDVQKNPGKASADIAYTLQQGREHFSYRQYVSCRTLLAGCAALRVKADQALWVDPKK-- 524 ++++P AD+AYTL GR F +R+ V C+ + L K Q + ++ Sbjct: 485 ANHLKQHPDLNLADVAYTLGIGRRAFVHRRMVVCQDIEDAIKVLEAKDPQRVLTHYQEPG 544 Query: 525 ELKPVYFWFAGMALEEAVQHYHSCLHHPYCREEMEELLLQASGIRGVKRDELL------- 577 EL+ V F F G + P RE++++ Q I + +L Sbjct: 545 ELE-VVFMFPGQGSQSVAMGRELYQTEPIFREQVDDCCEQLKHILELDLRTILYPCEEQT 603 Query: 578 ----SGGSDVYIGQTPVFLFQLALAKWLLRVGVKPAALMGTGTGAYVAGCLAGVFTLEEA 633 + +I Q +F+ + ALA+ L GV P+A++G G YVA CLAGVF+LE+A Sbjct: 604 QWATEQLTQTHITQPALFVVEYALAQLWLAKGVCPSAMIGHSIGEYVAACLAGVFSLEDA 663 Query: 634 LMLMEKRDRLLEE 646 LML+ KR +L+++ Sbjct: 664 LMLVAKRGQLMQQ 676 Score = 68.9 bits (167), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 48/174 (27%), Positives = 75/174 (43%), Gaps = 31/174 (17%) Query: 656 LLEALQSEFYEAFDSVTLSAPAIPLLSADAGS-NTVLDVTLPDYWVNALGAD---DDGKS 711 +++++ F V L+ P IP LS G+ T + T YWV L + DG S Sbjct: 747 MMDSIIEPFKSLLAKVNLNPPKIPFLSNVTGTWITTKEATDNSYWVKHLRSSVRFADGIS 806 Query: 712 LPAK-------------------AEEADKHLVLHFGAAGEPSGPSGYISLVKSGPELLET 752 K +++ LVL + G P ++ LL T Sbjct: 807 ELCKQPNRIFLEVGFGCTLSTLTKQQSQGQLVL--CSIGHPHNQQSDVAF------LLNT 858 Query: 753 VGCIWANGYPLQWDELAKHQNRARVILPTYPFTRKRYWVDTQQIKQFQNIWKRQ 806 +G +W G + W L H+ R R+ LPTYPF RKRYWV++ ++ + + +Q Sbjct: 859 LGNLWLYGIQVDWSSLYAHEKRYRLPLPTYPFERKRYWVESTKVNELNQLQNKQ 912 >gb|AAF15892.2| NosB [Nostoc sp. GSV224] Length = 1244 Score = 567 bits (1461), Expect = e-159, Method: Compositional matrix adjust. Identities = 301/667 (45%), Positives = 414/667 (62%), Gaps = 23/667 (3%) Query: 1 MKENTRTGLEVAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGVPAEVYTK 60 + N E+AII ++G FP AK+++ F+QN+ +GV+SIS TDE+L +GV ++ Sbjct: 5 LNTNDFNNSEIAIISLAGRFPKAKDIDSFWQNLYDGVESISRLTDEELITSGVSLDLLNN 64 Query: 61 ENFVKAKGYLNECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAI 120 N+VKA L++ E FD +FF Y+ EA+ +DPQ RL E AW A+E AGY P I Sbjct: 65 PNYVKASAVLSDIELFDANFFAYSAKEAELIDPQQRLFLELAWEAIEKAGYDPHTYNGLI 124 Query: 121 GVYAG-GRPHFHWEALSLSMGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFTA 179 GVYAG G + L + ++ NDKD + TRV+YKLNL G + + TA Sbjct: 125 GVYAGVGMNRYLVNNLYPHHQLLETVDPLQLTISNDKDFLPTRVAYKLNLTGTAVNVQTA 184 Query: 180 CSTSLVAVHAACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAASD 239 CSTSLVAVH ACQ +++ ECDMA+AGGV+++ P + GY HQ+GMILS DG CRAFDA + Sbjct: 185 CSTSLVAVHLACQSLLNYECDMALAGGVTLSIPQKIGYLHQEGMILSPDGHCRAFDAKAQ 244 Query: 240 GTVVGNGIGLVILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRTA 299 GT+ +G G+V+LKRL+DA+ D DHI+A+IKG+AINNDG+ KVG++APSV GQA VI A Sbjct: 245 GTIASSGAGIVVLKRLKDAIADRDHIHAIIKGSAINNDGAMKVGFTAPSVSGQAAVIAEA 304 Query: 300 HRVAGVDPKEIGYIEAHGTGTALGDPIEVKALTTAFQ--TKRKHFCGLGSVKTNIGHLDS 357 +AGVD + I YIEAHGT T LGDPIE+ ALT AF T +K FC +GS+KTN+GHLD+ Sbjct: 305 QAIAGVDAETISYIEAHGTATPLGDPIEIAALTQAFSQTTDKKGFCAIGSLKTNLGHLDT 364 Query: 358 AAGIAGLIKAVLALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWENGSGPRRAGVS 417 AAG+AGLIK VLAL NK L P+LHF PNP + +SPFY+ + EW + PRRAGVS Sbjct: 365 AAGVAGLIKTVLALQNKMLPPSLHFETPNPKIDFANSPFYVNTTLTEWRTNTTPRRAGVS 424 Query: 418 SFGVGGTNAHIVLEEAPSGQSVKQAEAQE----QLLVFSAKTREALEQSIEAFVQDVQKN 473 SFG+GGTNAH++LEEAP + + ++ QLLV SAKT ALE++ + ++++ Sbjct: 425 SFGIGGTNAHVILEEAPMFEQGSRGAGEQGRNYQLLVLSAKTASALEKATANLITHLKEH 484 Query: 474 PGKASADIAYTLQQGREHFSYRQYVSCRTLLAGCAAL-RVKADQALWVDPKKELKPVYFW 532 P D+AYTL GR F+YR+ + C+ L L ++A Q + + V F Sbjct: 485 PELDLGDVAYTLNSGRRGFNYRRMLICQDLEDAVKTLSSLEAQQVFSNYTEITERSVVFM 544 Query: 533 FAG-----MALEEAVQHYHSCLHHP--YCREEMEELLLQASGIRGV------KRDELLSG 579 F G + + + + YC E ++ LL +R + K DE Sbjct: 545 FPGQGSQYVNMAREIYQTETVFKEQVDYCSEVLKPLL--GIDLRHILYPSEEKIDEASKQ 602 Query: 580 GSDVYIGQTPVFLFQLALAKWLLRVGVKPAALMGTGTGAYVAGCLAGVFTLEEALMLMEK 639 + Q +F+ + AL K GV+P A +G G YVA LA VF+LE+AL L+ Sbjct: 603 LQQTAVAQPAIFVIEYALPKLWQSYGVQPQAAIGHSIGEYVAATLAEVFSLEDALSLVAA 662 Query: 640 RDRLLEE 646 R +++++ Sbjct: 663 RGQMMQQ 669 Score = 63.2 bits (152), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 55/200 (27%), Positives = 78/200 (39%), Gaps = 32/200 (16%) Query: 620 VAGCLAGVFTLEEALMLMEKRDRLLEEWRGSEGDLFLLEALQSEFYEAFDSVTLSAPAIP 679 V+G A + TL+ L R L + +E + F E VTL+ P +P Sbjct: 706 VSGSTAAIDTLQNQLAAQGIECRQLHTSHAFHSQM--MEPILKAFVERVKKVTLNPPKLP 763 Query: 680 LLSADAGS-NTVLDVTLPDYWVNALGADDDGKSLPAKAEEADKHLVLHFGAAGEPSGPSG 738 +S G+ TV T PDY+ L +S A+ +K L E + Sbjct: 764 YISNLTGNWITVTQATNPDYYAQHL------RSTVLFAQGVEKLLATPEQVLLEVGPGNT 817 Query: 739 YISLVKSGPE-----------------------LLETVGCIWANGYPLQWDELAKHQNRA 775 +LVK P+ L T+G +W G + W HQ Sbjct: 818 LTTLVKRHPDKAATQTVLTSVRHPQEKQSDNHVLFTTLGQLWLAGVNIDWFGFYSHQEHY 877 Query: 776 RVILPTYPFTRKRYWVDTQQ 795 R+ LPTYPF R+RYW+D Q Sbjct: 878 RLPLPTYPFERQRYWIDPPQ 897 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.135 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 3,162,098,753 Number of extensions: 131794989 Number of successful extensions: 329466 Number of sequences better than 1.0e-05: 2546 Number of HSP's gapped: 318132 Number of HSP's successfully gapped: 3836 Length of query: 2184 Length of database: 757,237,578 Length adjustment: 141 Effective length of query: 2043 Effective length of database: 374,408,619 Effective search space: 764916808617 Effective search space used: 764916808617 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)