BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0027.p (882 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value emb|CAE11248.1| BmyC protein [Bacillus amyloliquefaciens] 525 e-147 ref|NP_389715.1| peptide synthetase [Bacillus subtilis] >gi|7303... 520 e-146 emb|CAA09819.1| fengycin synthetase [Bacillus subtilis] 516 e-145 emb|CAE11276.1| FenB [Bacillus amyloliquefaciens] 498 e-139 ref|ZP_00111185.1| COG3319: Thioesterase domains of type I polyk... 496 e-138 >emb|CAE11248.1| BmyC protein [Bacillus amyloliquefaciens] Length = 2619 Score = 525 bits (1353), Expect = e-147, Method: Compositional matrix adjust. Identities = 316/871 (36%), Positives = 470/871 (53%), Gaps = 55/871 (6%) Query: 16 YKKEQQYWLHKLAGLPDKSHFPCEPHKDRHQERHIETIPFSLDPVHARKLVQISNDSDAR 75 +K+ YW + L G ++ E DR + F L ++ + ++ Sbjct: 1511 HKQASAYWRNYLEGYEGQTVLLQEQSSDRAKGYEKGEHEFRLGKRLTDEIKRAASRQQVT 1570 Query: 76 LHVLLLAFTSVWLLKYSGQTDIVLGTSIYRQPSEED--------FINTVLPVRVQVQNEM 127 ++ + + L +Y+G D+V GT + +P+E FINT+ PVR+ Q EM Sbjct: 1571 VNTWIQTAWGLLLQRYNGSQDVVFGTVVSGRPAEIPGIETMVGLFINTI-PVRIHTQPEM 1629 Query: 128 RLIDLISL-------------------------MKQTVSEAARHQNYPFELMLKQAGLDS 162 ++ + +Q ++ +NYP E ++ D Sbjct: 1630 TAAQVLKMNQERALASQKYDTFPLYDIQAQTEQKQQLINHIMVFENYPVEKQIEHMKQDD 1689 Query: 163 GFLDVSVIVSNIQDEQYLSGTLSNFTMIVHREESVLQGEIRF--NAAVYSADTVNQLLEH 220 LD I D T +FT IV + + +IRF N VY +V ++ H Sbjct: 1690 NALD-------ILDFHMEEHTHYDFTFIVMPDGEI---DIRFVYNRDVYDQASVERMQTH 1739 Query: 221 FHVLLEQSLADLHSSVQELSILTEKDRRI-IACSNATSAGFPEEATIPALFEECAAKYPN 279 F +++Q D VQ+L I+T +R + I N T+A +P+E TI LFEE A + P Sbjct: 1740 FMQIMKQMADDQEIRVQDLDIVTADERSLLIDKFNDTAAEYPKEKTIHQLFEEQAERTPE 1799 Query: 280 HTAAEFADERLSYQDLNRKANQAAHHLRRLGVTAESVVALILPPSLEMIIGILAVLKAGG 339 A F D++++Y+ +N +ANQ A L G+ AE +V ++ S EM+IGILA+LKAGG Sbjct: 1800 QAAIVFEDKKMTYRIVNERANQLARTLVAKGLQAEELVGIMAERSPEMVIGILAILKAGG 1859 Query: 340 AYLPIDPDLPAQRVDYILKDSQAGQILTVQSLSLPPGTGESCEVIFLDDPMLEQYSSSNL 399 Y+PIDPD P +R+ Y+L+DS IL +Q L GT +FLDDP +SNL Sbjct: 1860 VYVPIDPDYPKERIHYMLEDSNVS-ILLLQH-HLLEGTDYQSHTVFLDDPSSYGAEASNL 1917 Query: 400 EHVIHPHDLAYIIYTSGTTGNPKGVMIEHRNVVRLFFHEHNRFDFTCQDTWTLFHSFGFD 459 + + P+ LAY+IYTSGTTGNPKG +IEH+NVVRL F+ N FDF DTWTLFHSF FD Sbjct: 1918 KLNVMPNQLAYVIYTSGTTGNPKGTLIEHKNVVRLLFNNKNVFDFNASDTWTLFHSFCFD 1977 Query: 460 FSVWEIFXXXXXXXXXXXXXXXXXRDYRHIVQELRNEHVTVFNQTPSSFYQFMQEELEDT 519 FSVWE++ ++ +Q L++E VT+ NQTPS FYQ MQEE D Sbjct: 1978 FSVWEMYGALLYGGKLVIIPKQIAKNPERYLQLLKSEAVTILNQTPSYFYQLMQEERADP 2037 Query: 520 GEKLRLRYVILGGEALQPGKLEAWKVKYPGTRIINMYGITETTVHTTFKEIGTEQIQANQ 579 L +R +I GGEAL P L+ WK+KYP T++INMYGITETTVH T+KEI +I + Sbjct: 2038 ESNLNIRKIIFGGEALNPSFLKDWKLKYPLTQLINMYGITETTVHVTYKEITEREIDEGR 2097 Query: 580 NNIGVPFSTVEVYIFNRQHEQVPIXXXXXXXXXXXXXXXXYLNRTELTEDRFQTRRMGDR 639 +NIG P T++ YI + + YLNR ELT ++F Sbjct: 2098 SNIGQPIPTLQAYILDEYQRIQVMGIPGELYVAGEGLARGYLNRPELTGEKFVEHPFA-A 2156 Query: 640 WIRLYRTGDLGRYLPSGELEYVGRRDNQVKIRGFRIELDEISAHLLTVESIKEAVVSARE 699 ++Y+TGD+ R+LP G +EY+GR D+QVKIRG+RIE+ E+ A LL +ES+KEAVV A E Sbjct: 2157 GEKMYKTGDVARWLPDGNIEYLGRIDHQVKIRGYRIEIGEVEAALLQLESVKEAVVIAIE 2216 Query: 700 IEPNAQILVAYVVIKEGQEAAFDPVEIRQYLQTRISDYMIPSVLLPLSKIPLTLNGKVDY 759 E + Q L AY+ + + + +++ +L ++ YMIP+ + + K+P+T NGK+D Sbjct: 2217 EEGSKQ-LCAYL----SGDDSLNTAQLKHHLLNKLPAYMIPAYFVQMEKMPITANGKIDR 2271 Query: 760 EKLDTLELKQQAKGVLTPPTTEMEHRIAEIWKTSLRMDRIGVHSTIFDLGGTSFDVITIS 819 + L E + P T +E ++AEIWK L + G+ FD+GG S V+ + Sbjct: 2272 KALPAPEGNRLTGTEYEAPGTLIEKQLAEIWKNILALSDPGIKDNFFDVGGHSLKVLQVI 2331 Query: 820 KALSEELGQEVPVITLFTYPTISMLAKVLQA 850 +++ +G ++ ++ +PTI +A+ +QA Sbjct: 2332 HQINDRMGIKMHYQAVYDFPTIETMARAIQA 2362 Score = 391 bits (1004), Expect = e-107, Method: Compositional matrix adjust. Identities = 267/871 (30%), Positives = 439/871 (50%), Gaps = 45/871 (5%) Query: 16 YKKEQQYWLHKLAGLPDKSHFPCEPHKDRHQERHIETIP----FSLDPVHARKLVQISND 71 +K+++ +W S P D E + P SL + ++++++N Sbjct: 4 FKQQELFWSSMFDAEDRPSAIPSFQMSDSTIEHDASSAPNRIHSSLSSDVSLRIMKMTNK 63 Query: 72 SDARLHVLLLAFTSVWLLKYSGQTDIVLGTSIYRQPSEEDF-INTVLPVRVQVQNEMRLI 130 S ++++LL L KY+G+ +V+G + ++ED ++ V+ ++ + + Sbjct: 64 SPMAVYMVLLVGIECLLYKYTGEEGVVVGVPTFEDETDEDLRLDQVMLIKQNINADSTFK 123 Query: 131 DLISLMKQTVSEAARHQNYPFELMLKQAGL--DSGFLD-VSVIVSNIQ------DEQYLS 181 + + K ++ A HQ+ PF+ M L DS L + IVS Q E + Sbjct: 124 SIFNEFKHKLNGAILHQHVPFDKMAGPLNLNYDSNHLPMIHTIVSLDQLHPIRFIETAAA 183 Query: 182 GTLSNFTMIVHREESVLQGEIRFNAAVYSADTVNQLLEHFHVLLEQSLADLHSSVQELSI 241 TL F++ E + ++ +N Y + Q++EH + + L +++L+I Sbjct: 184 DTLFQFSI----ENDSIHLKLTYNEQAYDRQYMMQVIEHVNRIFSILLFQPDLMIRQLNI 239 Query: 242 LTEKDRRIIACSNATSAGFPEEATIPALFEECAAKYPNHTAAEFADERLSYQDLNRKANQ 301 L++ + + N T+A +P E TI EE A + P+ TA + D RL+Y++LN +ANQ Sbjct: 240 LSDSETNQLIAYNQTAAEYPREKTIHQFLEEQAERTPDQTAVVYEDSRLTYRELNERANQ 299 Query: 302 AAHHLRRLGVTAESVVALILPPSLEMIIGILAVLKAGGAYLPIDPDLPAQRVDYILKDSQ 361 A L+ GV + V ++ SL+MI+GI +LKAGGAY+PIDP P +RV YIL+DS Sbjct: 300 LARTLQSEGVQPDQPVGIMAERSLDMIVGIFGILKAGGAYVPIDPGYPEERVRYILEDSD 359 Query: 362 AGQILTV-QSLSLPPGTGESCEVIFLDDPMLEQYSSSNLEHVIHPHDLAYIIYTSGTTGN 420 +L QS P TG +V+ + DP SN+E P LAY+IYTSG+TG Sbjct: 360 TKLLLVQNQSQERVPFTG---KVLDMKDPQNFCEDGSNVEPAAGPDHLAYVIYTSGSTGK 416 Query: 421 PKGVMIEHRNVVRLFFHEHNRFDFTCQDTWTLFHSFGFDFSVWEIFXXXXXXXXXXXXXX 480 PKGVM+EHR+V+ ++ +D + FD SVWE+F Sbjct: 417 PKGVMVEHRSVINRLVWMQEKYPLDERDAILQKTAITFDVSVWELFWWTISGSRLVLLPN 476 Query: 481 XXXRDYRHIVQELRNEHVTVFNQTPSSFYQFMQEELEDTGEKLR-----LRYVILGGEAL 535 ++ I+ + + V+ + P+ + F++ + L+ LR+V GEAL Sbjct: 477 GGEKNPELILDTIAQKGVSTMHFVPAMLHAFLESMDQKPSGMLKQKLASLRHVFASGEAL 536 Query: 536 QPGKLEAWK---VKYPGTRIINMYGITETTVHTTFKEIGTEQIQANQNNIGVPFSTVEVY 592 +P + +K +IIN+YG TE T+ ++ + TE+ A+ IG P S +++Y Sbjct: 537 KPVHVAGFKRIITSVSQAQIINLYGPTEATIDVSYFDCQTEETYASI-PIGKPISNIQLY 595 Query: 593 IFNRQHEQV-PIXXXXXXXXXXXXXXXXYLNRTELTEDRFQTRRMGDRWIRLYRTGDLGR 651 I + E + PI YLNR ELT ++F + R+YRTGDL R Sbjct: 596 ILHADLEHMQPIGVAGELCIAGDGLARGYLNRPELTAEKFVNHPIASGE-RIYRTGDLAR 654 Query: 652 YLPSGELEYVGRRDNQVKIRGFRIELDEISAHLLTVESIKEAVVSAREIEPNAQILVAYV 711 +LP G +EY+GR D+QVKIRG+RIE+ E+ + +IKEA++ AREI+ + Y Sbjct: 655 WLPDGNIEYLGRIDHQVKIRGYRIEIGEVEGAFFQLPAIKEAIIIAREIDGETSLCAYYT 714 Query: 712 VIKEGQEAAFDPVEIRQYLQTRISDYMIPSVLLPLSKIPLTLNGKVDYEKLDTLELKQQA 771 + A E+R+ L ++ YMIP+ + L ++PLT NGK+D + L + ++ Sbjct: 715 A-----QHALTAGELREELSRQLPSYMIPAYFVQLEEMPLTFNGKIDRKSLPS--PRENL 767 Query: 772 KGV-LTPPTTEMEHRIAEIWKTSLRMDRIGVHSTIFDLGGTSFDVITISKALSEELGQEV 830 G+ P TE+E +A +W+ L ++R+G+ F+LGG S I +S L + G + Sbjct: 768 TGMNYEAPRTELEKILAAVWEAVLGLERVGISDHFFELGGDSIKSIQVSSRLYQA-GYKF 826 Query: 831 PVITLFTYPTISMLAKVLQADSPVTELSAES 861 + LF YPTIS L ++ PVT ++ + Sbjct: 827 EIKHLFKYPTISELVPYVE---PVTRIAEQG 854 >ref|NP_389715.1| peptide synthetase [Bacillus subtilis] sp|P39846|PPS2_BACSU Peptide synthetase 2 pir||I40457 peptide synthetase ppsB - Bacillus subtilis emb|CAA84361.1| peptide synthetase ORF2 [Bacillus subtilis] emb|CAB13716.1| plipastatin synthetase [Bacillus subtilis subsp. subtilis str. 168] Length = 2560 Score = 520 bits (1339), Expect = e-146, Method: Compositional matrix adjust. Identities = 317/867 (36%), Positives = 477/867 (55%), Gaps = 43/867 (4%) Query: 14 DVYKKEQQYWLHKLAGLPDKSHFPCEPHKDRHQERHIETIPFSLDPVHARKLVQISNDSD 73 ++YKK++ YWL +L G P + + R + TI ++D A +L ++ ++ Sbjct: 1227 ELYKKQEAYWLGQLGGSLPTLELPLDKTRPRLPDFRGGTIEVNIDKDMADELHRLMAETG 1286 Query: 74 ARLHVLLLAFTSVWLLKYSGQTDIVLGTSIYRQPSEE------DFINTVLPVRVQVQNEM 127 L+++LLA S+ L K SGQ DIV+G+ +P + F+NT L +R + + Sbjct: 1287 TTLYMILLAVYSILLSKLSGQEDIVVGSPAAGRPHADLERVIGMFVNT-LAMRSKPEGHK 1345 Query: 128 RLIDLISLMKQTVSEAARHQNYPFELMLKQAGLDSG-------FLDVSVIVSNIQDEQY- 179 + ++ A HQ+YPFE + + LD+ D +++ + +D ++ Sbjct: 1346 TFSSYLHDIRHLALTAYEHQDYPFEELADK--LDTNREVNRNPLFDAMLVLQSSEDFRFE 1403 Query: 180 ---LSGT-------LSNFTMIVHREE--SVLQGEIRFNAAVYSADTVNQLLEHFHVLLEQ 227 LS + +S F + +H EE S ++ ++ A++ +T+ Q +F L++ Sbjct: 1404 VPGLSISSVTPKHDISKFDLTLHAEEHLSGIRCRFEYSTALFEEETITQWASYFIELVKG 1463 Query: 228 SLADLHSSVQELSILTEKDRRIIACSNATSAGFPEEATIPALFEECAAKYPNHTAAEFAD 287 AD + + +L +RR++ A +P I +LFE+ A+YP H A Sbjct: 1464 VTADTEMRISNMQLLPAAERRLLLEKMGQYAAYPRNENIVSLFEKQVAQYPEHIAVVCGH 1523 Query: 288 ERLSYQDLNRKANQAAHHLRRLGVTAESVVALILPPSLEMIIGILAVLKAGGAYLPIDPD 347 +L+Y+DLN KA +AA L + GV +V L+L S +MIIG+L++LKAGGAYLPIDP+ Sbjct: 1524 SQLTYRDLNEKAERAAAMLIKQGVRTGDIVGLMLDRSPDMIIGVLSILKAGGAYLPIDPE 1583 Query: 348 LPAQRVDYILKDSQAGQILTVQSLSLPPGTGESCEVIFLDDPMLEQYSSS-NLEHVIHPH 406 P +R+ ++L DS A +LT + L+ P + ++++D+ + N+E ++ Sbjct: 1584 YPKERISFMLNDSGAKLLLTERGLNKP--ADYTGHILYIDECENNSIPADVNIEEIVTDQ 1641 Query: 407 DLAYIIYTSGTTGNPKGVMIEHRNVVRLFFHEHNRFDFTCQDTWTLFHSFGFDFSVWEIF 466 AY+IYTSGTTG PKGV++EHRNV+ L H++ F+F +D WTLFHS+ FDFSVWE+F Sbjct: 1642 P-AYVIYTSGTTGQPKGVIVEHRNVISLLKHQNLPFEFNHEDVWTLFHSYCFDFSVWEMF 1700 Query: 467 XXXXXXXXXXXXXXXXXRDYRHIVQELRNEHVTVFNQTPSSFYQFMQEELEDTGEKLRLR 526 RD + L+ E VTV NQTP++FY M E+ T + L +R Sbjct: 1701 GALLNGSTLVVVSKETARDPQAFRLLLKKERVTVLNQTPTAFYGLMLEDQNHT-DHLNIR 1759 Query: 527 YVILGGEALQPGKLEAWKVKYPGTRIINMYGITETTVHTTFKEIGTEQIQANQNNIGVPF 586 YVI GGEALQPG L++W KYP T +INMYGITETTVH TFK++ I N++NIG P Sbjct: 1760 YVIFGGEALQPGLLQSWNEKYPHTDLINMYGITETTVHVTFKKLSAADIAKNKSNIGRPL 1819 Query: 587 STVEVYIFNRQHEQVPIXXXXXXXXXXXXXXXXYLNRTELTEDRFQTRRM--GDRWIRLY 644 ST++ ++ + P YLNR ELT DRF + GD RLY Sbjct: 1820 STLQAHVMDAHMNLQPTGVPGELYIGGEGVARGYLNRDELTADRFVSNPYLPGD---RLY 1876 Query: 645 RTGDLGRYLPSGELEYVGRRDNQVKIRGFRIELDEISAHLLTVESIKEAVVSAREIEPNA 704 RTGDL + L +GELEY+GR D QVK+RG RIEL EI A LL IKEA V R E Sbjct: 1877 RTGDLAKRLSNGELEYLGRIDEQVKVRGHRIELGEIQAALLQYPMIKEAAVITRADEQGQ 1936 Query: 705 QILVAYVVIKEGQEAAFDPVEIRQYLQTRISDYMIPSVLLPLSKIPLTLNGKVDYEKLDT 764 + AY+VIK+ Q A +IR YL+ + D+M+P+ ++ + IP+T+NGK+D + L Sbjct: 1937 TAIYAYMVIKDQQAANIS--DIRTYLKNALPDFMLPARMIQIDSIPVTVNGKLDQKALPE 1994 Query: 765 LELKQQAKGVLTPPTTEMEHRIAEIWKTSLRMDRIGVHSTIFDLGGTSFDVITISKALSE 824 E KQ P E+E +AEIW+ L +D +GV + F LGG S + + L + Sbjct: 1995 PE-KQAYTADDISPRNEIETVMAEIWEELLNVDELGVSANFFKLGGDSIKALQVCARLKQ 2053 Query: 825 ELGQEVPVITLFTYPTISMLAKVLQAD 851 G E V +F + T+ L+ ++ D Sbjct: 2054 R-GFETTVREMFEHQTLGELSARVRKD 2079 Score = 353 bits (907), Expect = 9e-96, Method: Compositional matrix adjust. Identities = 257/861 (29%), Positives = 411/861 (47%), Gaps = 55/861 (6%) Query: 22 YWLHKLAGLPDKSHFPCEPHKDRHQERHIETIPFSLDPVHARKLVQISNDSDARLHVLLL 81 YW L + + P + + + FSL P KL + + + L+ L + Sbjct: 201 YWSEYLKEYGNTASIPRIKRRTADGNYKADQVSFSLAPDMVEKLTEAAQNWGVTLNTLFM 260 Query: 82 AFTSVWLLKYSGQTDIVLGTSIYRQPSEED--------FINTVLPVRVQVQNEMRLIDLI 133 + V L +Y+ D V G+ I +PS D FINTV PVR++ + L+ Sbjct: 261 SIWGVLLHRYNAADDAVFGSVISGRPSAIDGIESMVGLFINTV-PVRIRSAEGITFSSLV 319 Query: 134 SLMKQTVSEAARHQNYPFELMLKQAGLDSGFLDVSVIVSN--IQDEQYLS-------GTL 184 +++ + + +H YP + + L G +D + N +Q Q LS G L Sbjct: 320 KAVQEDILSSEQHGYYPLYEIQNHSPLKQGLIDHIFVFENYPVQLHQALSVESENDEGAL 379 Query: 185 S------------NFTMIVHREESVLQGEIRFNAAVYSADTVNQLLEHFHVLLEQSLADL 232 +F +++ ES + +NA VY + + ++ H L+ L + Sbjct: 380 KLSDISMSEQTNYDFNIVIVPGESFYI-KFSYNADVYEREEMLRIQGHLKQALDCILTNP 438 Query: 233 HSSVQELSILTEKDRRIIACSNATSAGFPEEATIPALFEECAAKYPNHTAAEFADERLSY 292 +V +++I+ +++++I N T + + TIP LFEE A K P A + +E +Y Sbjct: 439 DVAVSDINIVPPEEQQVIQLFNETERPYVNK-TIPQLFEEQAHKTPEAAALKMGNECWTY 497 Query: 293 QDLNRKANQAAHHLRRLGVTAESVVALILPPSLEMIIGILAVLKAGGAYLPIDPDLPAQR 352 + L +ANQ AH L GV + +VA+++ S+EM +L + KAGGAY+P+DP PA+R Sbjct: 498 RQLQVRANQIAHALIEKGVGSGDIVAVMMGRSMEMPAALLGIWKAGGAYMPLDPHFPAER 557 Query: 353 VDYILKDSQAGQILTVQSL-SLPPGTGESCEVIFLDDPMLEQYSSSNLEHVIHPHDLAYI 411 + ++LKDSQA Q+L + L SL P + E I ++ Q + N+ P DLAY+ Sbjct: 558 LSFLLKDSQAAQLLIEEDLISLIPPSYEG-NTITIEHTESYQTEAPNMP----PGDLAYL 612 Query: 412 IYTSGTTGNPKGVMIEHRNVVRLFFHEHNRFDFTCQDTWTLFHSFGFDFSVWEIFXXXXX 471 IYTSGTTG PKGV+++H + + T QD S+ FD V +F Sbjct: 613 IYTSGTTGRPKGVLVDHHGIANTLQWRREEYSMTEQDISLHLFSYVFDGCVTSLFTPLLS 672 Query: 472 XXXXXXXXXXXXRDYRHIVQELRNEHVTVFNQTPSSFYQFMQEELEDTGEKLRLRYVILG 531 +D + +++ V+ PS + ++ D + LR+ V Sbjct: 673 GACVLLTTDDEAKDVLALKRKIARYKVSHMIIVPSLYRVLLEVMTADDAKSLRI--VTFA 730 Query: 532 GEALQPGKLEAWKVKYPGTRIINMYGITETTVHTTFKEIGTEQIQANQNNIGVPFSTVEV 591 GEA+ P LE ++ P + N YG TE +V TT I + + IG P +V Sbjct: 731 GEAVTPDLLELNQIICPSAELANEYGPTENSVATT---ILRHLNKKERITIGHPIRNTKV 787 Query: 592 YIFNRQHEQVPIXXXXXXXXXXXXXXXXYLNRTELTEDRFQTRRM--GDRWIRLYRTGDL 649 ++ + Q PI Y + ELT+ F G+ RLYRTGD Sbjct: 788 FVLHGNQMQ-PIGAAGELCISGAGLARGYYKQQELTQKAFSDHPFLEGE---RLYRTGDA 843 Query: 650 GRYLPSGELEYVGRRDNQVKIRGFRIELDEISAHLLTVESIKEAVVSAREIEPNAQILVA 709 GR+LP G +EY+GR D+QVKIRG+RIEL EI L +KEA V AR++ + LVA Sbjct: 844 GRFLPDGTIEYIGRFDDQVKIRGYRIELREIETVLRQAPGVKEAAVLARDVSAEEKELVA 903 Query: 710 YVVIKEGQEAAFDPVEIRQYLQTRISDYMIPSVLLPLSKIPLTLNGKVDYEKLDTLELKQ 769 Y+V ++G ++ Q+L + YMIP+ ++ +S++PLT +GK+D + E + Sbjct: 904 YIVPEKGNSLP----DLYQHLAGTLPSYMIPASIINISQMPLTSSGKLD--RFALPEPEN 957 Query: 770 QAKGVLTPPTTEMEHRIAEIWKTSLRMDRIGVHSTIFDLGGTSFDVITISKALSEELGQE 829 P T +E +A IW+ L IG+ F LGG S + + ++L E Sbjct: 958 NTSVTYMAPRTLIEADLAHIWEDVLNKQHIGIRDDFFQLGGQSLKAAALVSRIHKKLNVE 1017 Query: 830 VPVITLFTYPTISMLAKVLQA 850 +P+ +F+YPT+ +A L + Sbjct: 1018 LPLSEVFSYPTVESMAVKLMS 1038 >emb|CAA09819.1| fengycin synthetase [Bacillus subtilis] Length = 2571 Score = 516 bits (1330), Expect = e-145, Method: Compositional matrix adjust. Identities = 311/862 (36%), Positives = 475/862 (55%), Gaps = 38/862 (4%) Query: 16 YKKEQQYWLHKLAGLPDKSHFPCEPHKDRHQERHIETIPFSLDPVHARKLVQISNDSDAR 75 Y K++ YWL +L G P + + + T ++D A +L ++ ++ Sbjct: 1229 YSKQEAYWLKQLGGSLPVLDLPLDKTRPLLPDFSGGTFEVNIDKRTAEELHRLMFETGTT 1288 Query: 76 LHVLLLAFTSVWLLKYSGQTDIVLGTSIYRQPSEE------DFINTVLPVRVQVQNEMRL 129 +++LLLA S+ L K SGQ DIV+G+ +P + F+NT L +R Q + Sbjct: 1289 MYMLLLAVYSIMLSKLSGQEDIVVGSPAAGRPHADLERVIGMFVNT-LAMRCQPEGRKTF 1347 Query: 130 IDLISLMKQTVSEAARHQNYPFE-----LMLKQAGLDSGFLDVSVIVSNIQDEQY----- 179 + +++ A HQ+YPFE L K+ + D +++ N +D Q+ Sbjct: 1348 SSYLQEIRELALTAYEHQDYPFEELVNKLETKREVNRNPLFDAMLVLQNSEDFQFEVPGL 1407 Query: 180 ------LSGTLSNFTMIVHREE--SVLQGEIRFNAAVYSADTVNQLLEHFHVLLEQSLAD 231 S +S F + +H EE + ++ ++ A++ +T+ + HF L++ +D Sbjct: 1408 SISSVTPSHNVSKFDLTLHAEEHSNGIRCRFEYSTALFEEETIARWASHFIELVKGITSD 1467 Query: 232 LHSSVQELSILTEKDRRIIACSNATSAGFPEEATIPALFEECAAKYPNHTAAEFADERLS 291 +H + E+ +L+ R ++ + A +P + +I LFE+ AA++P HTA RL+ Sbjct: 1468 IHMKLSEMQLLSAPARELLLETMGQYADYPRDESIVRLFEKQAAEHPEHTAVVCDHIRLT 1527 Query: 292 YQDLNRKANQAAHHLRRLGVTAESVVALILPPSLEMIIGILAVLKAGGAYLPIDPDLPAQ 351 Y+DLN KA + A L + GV + ++ L+ S +M+IG+L++LKAGGAYLPIDP+ P + Sbjct: 1528 YRDLNEKAERTATMLMKQGVRSGDIIGLMFDRSPDMVIGVLSILKAGGAYLPIDPEYPQE 1587 Query: 352 RVDYILKDSQAGQILTVQSLSLPPGTGESCEVIFLDDPMLEQYSSSNLEHVIHPHDLAYI 411 R+ ++L DS A +LT + P ++++L+D E S AY+ Sbjct: 1588 RISFMLNDSGARILLTEHGHNKP--ADYHGQILYLNDAENELISPDLKAQETLADQPAYV 1645 Query: 412 IYTSGTTGNPKGVMIEHRNVVRLFFHEHNRFDFTCQDTWTLFHSFGFDFSVWEIFXXXXX 471 IYTSGTTG PKGV++EHRNV+ L H+ FDF +D WTLFHS+ FDFSVWE+F Sbjct: 1646 IYTSGTTGQPKGVVVEHRNVISLLKHQDLPFDFGSEDVWTLFHSYCFDFSVWEMFGALLN 1705 Query: 472 XXXXXXXXXXXXRDYRHIVQELRNEHVTVFNQTPSSFYQFMQEELEDTGEKLRLRYVILG 531 RD L+NE VTV NQTP++FY + EE E+ ++L +RYVI G Sbjct: 1706 GSTLVVVSRETARDPNAFRLLLKNEGVTVLNQTPTAFYGLIHEE-ENHTDRLHVRYVIFG 1764 Query: 532 GEALQPGKLEAWKVKYPGTRIINMYGITETTVHTTFKEIGTEQIQANQNNIGVPFSTVEV 591 GEALQPG L W KYP T +INMYGITETTVH T+K++ + I+ N++NIG P +T++ Sbjct: 1765 GEALQPGMLVTWNEKYPDTDLINMYGITETTVHVTYKKLSSADIEKNKSNIGKPLATLQA 1824 Query: 592 YIFNRQHEQVPIXXXXXXXXXXXXXXXXYLNRTELTEDRFQTRRM--GDRWIRLYRTGDL 649 Y+ + P YLNR +LT RF GD RLYRTGDL Sbjct: 1825 YVMDAHMNLQPTGVPGELYIGGEGVARGYLNRDDLTAARFVPNPYLPGD---RLYRTGDL 1881 Query: 650 GRYLPSGELEYVGRRDNQVKIRGFRIELDEISAHLLTVESIKEAVVSAREIEPNAQILVA 709 + L SG+LEY+GR D+QVK+RG RIEL EI A LL + IKEA V R+ E + A Sbjct: 1882 AKRLASGDLEYMGRIDDQVKVRGHRIELGEIQASLLQLPIIKEAAVITRDDEQGQSAVYA 1941 Query: 710 YVVIKEGQEAAFDPVEIRQYLQTRISDYMIPSVLLPLSKIPLTLNGKVDYEKLDTLELKQ 769 Y+V ++GQ + +IR L+ + D+M+P+ L+ + IPLT+NGK+D + L + + Sbjct: 1942 YLVAEDGQ--VVNEADIRAALRAVLPDFMVPARLIQIDSIPLTVNGKLDQKALPEPDKRA 1999 Query: 770 QAKGVLTPPTTEMEHRIAEIWKTSLRMDRIGVHSTIFDLGGTSFDVITISKALSEELGQE 829 QA+ ++ P E+E +A+IW+ L + IGV + F+LGG S + + L + G E Sbjct: 2000 QAENDIS-PRNEIEKAMADIWEELLEAEEIGVSANFFELGGDSIKALQVCARLKQR-GYE 2057 Query: 830 VPVITLFTYPTISML-AKVLQA 850 V +F + T+ L A+V +A Sbjct: 2058 TTVREMFEHQTLGELSARVRKA 2079 Score = 369 bits (946), Expect = e-100, Method: Compositional matrix adjust. Identities = 267/860 (31%), Positives = 421/860 (48%), Gaps = 56/860 (6%) Query: 22 YWLHKLAGLPDKSHFPCEPHKDRHQERHIETIPFSLDPVHARKLVQISNDSDARLHVLLL 81 YW L + + P + + E I SL+P +KL + + L+ L + Sbjct: 201 YWRDYLQEYGNTASIPKLKSRSANGEYEAANIRLSLEPAIVQKLTAAAQNWGVTLNTLFM 260 Query: 82 AFTSVWLLKYSGQTDIVLGTSIYRQPSEED--------FINTVLPVRVQVQNEMRLIDLI 133 + V L +Y+G D V G+ + +PS D FINTV PVR++ +M L+ Sbjct: 261 SLWGVLLHRYNGTDDAVFGSVVSGRPSAIDGIESMVGLFINTV-PVRIRSAEKMAFSTLV 319 Query: 134 SLMKQTVSEAARHQNYPFELMLKQAGLDSGFLDVSVIVSN--IQDEQYLSGTLSN----- 186 +++ + +H YP + + L G +D ++ N +Q +Q ++ N Sbjct: 320 KSVQEDTLRSEQHGYYPLYEIQNSSALKQGLIDHILVFENYPVQLQQAVNRQSENDENAL 379 Query: 187 -FTMIVHREES-------VLQGE-----IRFNAAVYSADTVNQLLEHFHVLLEQSLADLH 233 I E++ ++ GE +NAAVY + V ++ H ++ L++ Sbjct: 380 KLDDISMSEQTSYDLNVVIVPGESFYIKFSYNAAVYEREEVLRIQGHLMEAMDCILSNPD 439 Query: 234 SSVQELSILTEKDRRIIACSNATSAGFPEEATIPALFEECAAKYPNHTAAEFADERLSYQ 293 +V ++I+ ++R++I N T +P + T+ LFEE A K P+ A DE +Y+ Sbjct: 440 IAVDSINIVPTEERKLIQSFNETERHYPNK-TLSQLFEEQALKTPDAAALRMGDECRTYR 498 Query: 294 DLNRKANQAAHHLRRLGVTAESVVALILPPSLEMIIGILAVLKAGGAYLPIDPDLPAQRV 353 L+ +ANQ AH L G + +VA+++ S++M +L + KAGGAYLP+DP P +R+ Sbjct: 499 QLDERANQIAHALIEKGAGSGGIVAVMMERSMDMAAALLGIWKAGGAYLPLDPSYPKERL 558 Query: 354 DYILKDSQAGQILTVQSL--SLPPGTGESCEVIFLDDPMLEQYSSSNLEHVIHPHDLAYI 411 ++L DSQA +LT + L S+P G E + Y + + + I +LAY+ Sbjct: 559 SFLLHDSQAALLLTEEELISSIPSG----YEGSIVTSGHTTHYRTDSPDASI--GELAYL 612 Query: 412 IYTSGTTGNPKGVMIEHRNVVRLFFHEHNRFDFTCQDTWTLFHSFGFDFSVWEIFXXXXX 471 IYTSGTTG PKGV+++H+ + + + DT S+ FD V +F Sbjct: 613 IYTSGTTGRPKGVLVDHQGIANTLQWRREEYGMSEGDTALHLFSYVFDGCVTSLFTPLLS 672 Query: 472 XXXXXXXXXXXXRDYRHIVQELRNEHVTVFNQTPSSFYQFMQEELEDTGEKLRLRYVILG 531 +D + +++ V+ P S Y+ + E L K LR V Sbjct: 673 GACVLLTTDNEAKDVLALRRKIAQYKVSHMLIVP-SLYRVLLEVLTAEDAK-SLRIVTFA 730 Query: 532 GEALQPGKLEAWKVKYPGTRIINMYGITETTVHTT-FKEIGTEQIQANQNNIGVPFSTVE 590 GEA+ P LE + P + N YG TE +V TT + + E+ + IG P + + Sbjct: 731 GEAVTPDLLETSRKICPSAELANEYGPTENSVATTILRHLNEEE----RITIGHPIANTK 786 Query: 591 VYIFNRQHEQV-PIXXXXXXXXXXXXXXXXYLNRTELTEDRFQTRRMGDRWIRLYRTGDL 649 VYI Q EQ+ PI Y RTELTE F T + RLYRTGD Sbjct: 787 VYIL--QGEQLQPIGAAGELCISGAGLARGYYKRTELTEKAF-TDHPFLKGERLYRTGDA 843 Query: 650 GRYLPSGELEYVGRRDNQVKIRGFRIELDEISAHLLTVESIKEAVVSAREIEPNAQILVA 709 GR+LP G +EY+GR D+QVKIRG+RIEL EI L +KEA V AR++ + LVA Sbjct: 844 GRFLPDGTIEYIGRFDDQVKIRGYRIELSEIETVLRQASGVKEAAVLARDVSDEEKELVA 903 Query: 710 YVVIKEGQEAAFDPVEIRQYLQTRISDYMIPSVLLPLSKIPLTLNGKVDYEKLDTLELKQ 769 Y+V ++G + Q+L + YMIP+ ++ ++++PLT +GK+D L E + Sbjct: 904 YIVPEKGNGLP----NLHQHLAGTLPSYMIPASIIKITQMPLTSSGKLDRSALP--EPEN 957 Query: 770 QAKGVLTPPTTEMEHRIAEIWKTSLRMDRIGVHSTIFDLGGTSFDVITISKALSEELGQE 829 PP T ME +A IW+ L ++IG+ F LGG S T+ + + L E Sbjct: 958 TTSLTYMPPQTLMETELARIWEEGLNKNQIGIRDDFFQLGGQSLKAATLVSRIHKRLNIE 1017 Query: 830 VPVITLFTYPTI-SMLAKVL 848 +P+ +F+YPT+ SM AK++ Sbjct: 1018 LPLSDVFSYPTVESMAAKLM 1037 >emb|CAE11276.1| FenB [Bacillus amyloliquefaciens] Length = 2568 Score = 498 bits (1282), Expect = e-139, Method: Compositional matrix adjust. Identities = 314/861 (36%), Positives = 469/861 (54%), Gaps = 40/861 (4%) Query: 16 YKKEQQYWLHKLAGLPDKSHFPCEPHKDRHQERHIETIPFSLDPVHARKLVQISNDSDAR 75 +K+ ++YWL + P + + + + L A L Q+ +++ + Sbjct: 1235 FKRHERYWLETIGENIPVLDLPLDKKRPPLPDFSGSVVRTRLQKETAENLRQLMDETGST 1294 Query: 76 LHVLLLAFTSVWLLKYSGQTDIVLGT-SIYRQPSEED-----FINTVLPVRVQVQNEMRL 129 L+++LLA S++L K SGQ DIV+G+ + R +E D F+NTV +R + + + Sbjct: 1295 LYMILLASYSLFLSKLSGQEDIVVGSPAAGRSRAELDGVIGMFVNTV-AMRSRPKGDKTF 1353 Query: 130 IDLISLMKQTVSEAARHQNYPFELMLKQAGLDSG-------FLDVSVIVSNIQD-EQYLS 181 + +K AA HQ++PFE + ++ LD+ D +++ N D E L Sbjct: 1354 RAYLEEVKMLALGAAEHQDFPFEELAQK--LDTHREVNRNPLFDAMLVLQNSDDFEVNLP 1411 Query: 182 G----------TLSNFTMIVHREE---SVLQGEIRFNAAVYSADTVNQLLEHFHVLLEQS 228 G +S F + +H EE L ++ A++ DT+ + HF LL Q Sbjct: 1412 GLSVSSHAVKHDISKFDLTLHAEERPDGSLDFHFEYSTALFEKDTIERWAGHFKELLGQI 1471 Query: 229 LADLHSSVQELSILTEKDRRIIACSNATSAGFPEEATIPALFEECAAKYPNHTAAEFADE 288 +D + ++ +L +R+++ + +A +P TI +LFE A K PN AA + E Sbjct: 1472 ASDYERKLSDIHLLGINERQMLLQAENQTAEYPRHETIVSLFEAQAEKMPNQIAAVMSHE 1531 Query: 289 RLSYQDLNRKANQAAHHLRRLGVTAESVVALILPPSLEMIIGILAVLKAGGAYLPIDPDL 348 RL+Y++LN KA++ A L G+ + +V ++ S +M+IGIL +LKAGGAYLPIDPD Sbjct: 1532 RLTYRELNEKADRIADMLSENGIRSGQIVGIMTERSPDMLIGILGILKAGGAYLPIDPDY 1591 Query: 349 PAQRVDYILKDSQAGQILTVQSLSLPPGTGESCEVIFLDDPMLEQYSSSNLEHVIHPHDL 408 P +R+ ++L DS A +LT L + G V+++D P E S+ + +I P Sbjct: 1592 PDERISFMLTDSGARALLTQSGLGISGMDG--LPVLYIDKP--ESVSADRTKEMITPEQP 1647 Query: 409 AYIIYTSGTTGNPKGVMIEHRNVVRLFFHEHNRFDFTCQDTWTLFHSFGFDFSVWEIFXX 468 AY+IYTSGTTG PKGVM EHRNV+ L H+ FDF +D WTLFHS+ FDFSVWEIF Sbjct: 1648 AYVIYTSGTTGKPKGVMTEHRNVISLITHKGLPFDFGSEDVWTLFHSYCFDFSVWEIFGA 1707 Query: 469 XXXXXXXXXXXXXXXRDYRHIVQELRNEHVTVFNQTPSSFYQFMQEELEDTGEKLRLRYV 528 RD Q L++E VTV NQTP++F + EE T +KL+LRYV Sbjct: 1708 LLYGGKVVIVPKDTARDPHLYRQLLQSEGVTVLNQTPTAFSGLIHEEAGHT-DKLKLRYV 1766 Query: 529 ILGGEALQPGKLEAWKVKYPGTRIINMYGITETTVHTTFKEIGTEQIQANQNNIGVPFST 588 I GGEALQPG L++WK KYP T ++NMYGITETTVH T K++ + I+ N++NIG P T Sbjct: 1767 IFGGEALQPGMLKSWKEKYPETELVNMYGITETTVHVTCKKLNMDDIERNKSNIGRPLET 1826 Query: 589 VEVYIFNRQHEQVPIXXXXXXXXXXXXXXXXYLNRTELTEDRFQTRRMGDRWIRLYRTGD 648 + ++ + PI Y+NR +LT RF T +RLYRTGD Sbjct: 1827 LHAFVMDAYMNPQPIGIPGELYIGGEGVARGYVNRDDLTASRFITNPHVS-GMRLYRTGD 1885 Query: 649 LGRYLPSGELEYVGRRDNQVKIRGFRIELDEISAHLLTVESIKEAVVSAREIEPNAQILV 708 + + L +GELEYVGR+D QVK+RG RIEL EI + L + S+KEA V R + + Sbjct: 1886 IAKRLLNGELEYVGRKDAQVKVRGHRIELGEIKSALQELSSVKEAAVITRADQHGQHSIY 1945 Query: 709 AYVVIKEGQEAAFDPVEIRQYLQTRISDYMIPSVLLPLSKIPLTLNGKVDYEKLDTLELK 768 AY V+ G E EI+ L+ + +YMIP+ L+ L ++PLT NGK+D + L EL Sbjct: 1946 AYAVL-HGNE-KIKEAEIQASLRAFLPEYMIPARLIALDELPLTANGKLDEKALPQPEL- 2002 Query: 769 QQAKGVLTPPTTEMEHRIAEIWKTSLRMDRIGVHSTIFDLGGTSFDVITISKALSEELGQ 828 + G E E +A+IW+ L ++ +G ++ F LGG S + + L ++ G Sbjct: 2003 NDSLGDDISLRNETEEMMADIWEELLGVEGLGPNAHFFHLGGDSIKALQVCARLKQQ-GY 2061 Query: 829 EVPVITLFTYPTISMLAKVLQ 849 E V LF + T+ ++ L+ Sbjct: 2062 ETTVRELFEHQTLGEVSMRLR 2082 Score = 337 bits (863), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 258/884 (29%), Positives = 423/884 (47%), Gaps = 65/884 (7%) Query: 5 FFANVPYLNDVYKKE-QQYWLHKLAGLPDKSHFPCEPHKDRHQERHIETIPFSLDPVHAR 63 + + + +L K+E +W L + P +K E FSL+ + Sbjct: 186 YSSYIKWLRSRNKEETSAFWSRCLEDYGEVVSVPQTKNKPAQNGYASEHFQFSLESETVQ 245 Query: 64 KLVQISNDSDARLHVLLLAFTSVW---LLKYSGQTDIVLGTSIYRQPSEED--------F 112 KL I+ + L+ L FTS+W L +Y+G D V G+ + +PS F Sbjct: 246 KLTDIARSTGVTLNTL---FTSIWGLLLHRYNGTEDAVFGSVVSGRPSAIAGIESMAGLF 302 Query: 113 INTVLPVRVQVQNEMRLIDLISLMKQTVSEAARHQNYPFELMLKQAGLDSGFLDVSVIVS 172 INTV PVRV+ +M L+ +++ A H YP + ++GL L+ ++ Sbjct: 303 INTV-PVRVRAAGDMTFSSLLKKVQKESLAAEEHSYYPLYDIQNESGLQKDLLNHILVFE 361 Query: 173 N--IQDEQYLSG---------TLSNFTM-----------IVHREESVLQGEIRFNAAVYS 210 N +Q + ++G +L NF+M IV EE ++ +NA +Y Sbjct: 362 NYPVQMQTAVNGWKQTESSALSLENFSMAEETNYDLNVVIVPGEEFYVK--FSYNAGIYD 419 Query: 211 ADTVNQLLEHFHVLLEQSLADLHSSVQELSILTEKDRRIIACSNATSAGFPEEATIPALF 270 + + ++ H ++ D + +S++ ++ +I N T+ +PE T+ LF Sbjct: 420 REDMKRIKGHILEVISCVTEDPDRLLSSISLVPPEEEALIHSFNETNRPYPE-TTVHGLF 478 Query: 271 EECAAKYPNHTAAEFADERLSYQDLNRKANQAAHHLRRLGVTAESVVALILPPSLEMIIG 330 EE AAK P+ A + SY+ LN++ANQ AH LR G + + A++L S+ + Sbjct: 479 EEQAAKTPDQEALRYNGVSWSYKKLNQRANQIAHALREKGARPDQITAVMLRRSMSTVAA 538 Query: 331 ILAVLKAGGAYLPIDPDLPAQRVDYILKDSQAGQILTVQSL--SLPPGTGESCEVIFLDD 388 +L + K+G AY+PID + P +R+ ++L+DS+A ++T + L +PP S V+ +++ Sbjct: 539 LLGIWKSGSAYMPIDAEFPPERISFLLRDSEASLLVTEKDLLPLIPPHFKGS--VVIMEE 596 Query: 389 PMLEQYSSSNLEHVIHPHDLAYIIYTSGTTGNPKGVMIEHRNVVRLFFHEHNRFDFTCQD 448 + +Q ++ L V + AY+IYTSGTTG PKGV+++H+ + + T D Sbjct: 597 TVSQQ--TAPLPPVSDSGNWAYVIYTSGTTGRPKGVLVQHKAISNTLQWRREEYGMTEGD 654 Query: 449 TWTLFHSFGFDFSVWEIFXXXXXXXXXXXXXXXXXRDYRHIVQELRNEHVTVFNQTPSSF 508 S+ FD S+ +F +D I Q++ V+ P S Sbjct: 655 IALHLFSYVFDGSLTSLFTPLLSGACVLLTDEDDAKDVLSIKQKITRHGVSHLLIVP-SL 713 Query: 509 YQFMQEELEDTGEKLRLRYVILGGEALQPGKLEAWKVKYPGTRIINMYGITETTVHTTFK 568 Y+ + + L + LR V GEA P +EA + P ++N YG TE +V TT Sbjct: 714 YRVLLDSLTKKDAQT-LRAVTFAGEAATPDIVEASRGICPNAELLNEYGPTENSVATT-- 770 Query: 569 EIGTEQIQANQNNIGVPFSTVEVYIFNRQHEQVPIXXXXXXXXXXXXXXXXYLNRTELTE 628 I ++++ IG P + VYI + Q P+ Y + ELT+ Sbjct: 771 -ILRNLQKSSRITIGRPIANTSVYIMHGDRLQ-PVGAVGELCISGKGLADGYFQQKELTD 828 Query: 629 DRFQTR--RMGDRWIRLYRTGDLGRYLPSGELEYVGRRDNQVKIRGFRIELDEISAHLLT 686 F R G+ RLYRTGD R+LP G +EY+GR D+QVK+RG+RIEL EI L + Sbjct: 829 KVFTPHPFREGE---RLYRTGDAARFLPDGTIEYMGRFDDQVKVRGYRIELGEIETALRS 885 Query: 687 VESIKEAVVSAREIEPNAQILVAYVVIKEGQEAAFDPVEIRQYLQTRISDYMIPSVLLPL 746 + +KEA V+ R++ Q L AYVV+ E F P L R+ YMIP L Sbjct: 886 LSGVKEAAVTVRKMADGEQELAAYVVL-ENAGVTFKP---HAELAGRLPAYMIPGSFTKL 941 Query: 747 SKIPLTLNGKVDYEKLDTLELKQQAK-GVLTPPTTEMEHRIAEIWKTSLRMDRIGVHSTI 805 +++PL+++GK+D L E K+ + G P T +E + IW+ L+ + I + Sbjct: 942 TEMPLSVSGKLDRAALP--EPKEAERTGDYQAPRTMLETELLSIWQEVLKREHISMRDDF 999 Query: 806 FDLGGTSFDVITISKALSEELGQEVPVITLFTYPTISMLAKVLQ 849 F +GG S ++ + + L E+ V +F +PTI +A+ L+ Sbjct: 1000 FQIGGQSLKAASLVSNIHKRLQIELAVRHVFEHPTIESMARFLE 1043 >ref|ZP_00111185.1| COG3319: Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Nostoc punctiforme] Length = 4617 Score = 496 bits (1276), Expect = e-138, Method: Compositional matrix adjust. Identities = 303/866 (34%), Positives = 464/866 (53%), Gaps = 40/866 (4%) Query: 13 NDVYKKEQQYWLHKLAGLPDKSHFPCEPHKDRHQERHIETIPFSLDPVHARKLVQISNDS 72 D+ + + YW +LA P P + + Q F+L L+Q+S + Sbjct: 2404 GDILQSQLSYWQQQLADAPGLLSLPTDRPRPAVQSFAGAYQQFALSKQLTSGLIQLSQEQ 2463 Query: 73 DARLHVLLLAFTSVWLLKYSGQTDIVLGTSIYRQPSEED------FINTVLPVRVQVQNE 126 L + LLA L +Y+G DI+LG+ I + E F+NT++ +R + Sbjct: 2464 GVTLFMTLLAAYDTLLYRYTGVADILLGSPIANRDRSEIEGLIGFFVNTLV-MRTDLSGN 2522 Query: 127 MRLIDLISLMKQTVSEAARHQNYPFELMLK--QAGLD---SGFLDVSVIVSNIQDEQY-- 179 +L+ +++ +A HQ+ PFE++++ Q D + V+ ++ N Q Sbjct: 2523 PSFCELLDRVREMAMDAYSHQDLPFEMLVEALQPERDLSHTPLFQVAFVLQNAPMSQLEL 2582 Query: 180 ---------LSGTLSNF--TMIVHREESVLQGEIRFNAAVYSADTVNQLLEHFHVLLEQS 228 + GT S F T+++ + L G +N ++ + T+ ++ HF LLE Sbjct: 2583 TGLTVSPLVVEGTTSRFDLTLLMENTGTGLVGLWEYNTDLFDSSTIERMTGHFMTLLEGI 2642 Query: 229 LADLHSSVQELSILTEKDR-RIIACSNATSAGFPEEATIPALFEECAAKYPNHTAAEFAD 287 +A+ + +L +LT+ ++ +++ N T +P++ I LFEE + P+ A + + Sbjct: 2643 IANPEERISQLPLLTQVEQHQLLVEWNDTQVDYPQDQCIHQLFEEQVERTPDAVAVVYEN 2702 Query: 288 ERLSYQDLNRKANQAAHHLRRLGVTAESVVALILPPSLEMIIGILAVLKAGGAYLPIDPD 347 ++ +Y++LN KANQ AH+L+ LGV + VV L + SLE I+GIL +LKAGGAY+P+DP+ Sbjct: 2703 QQFTYRELNAKANQLAHYLQTLGVGPDVVVGLCVERSLETIVGILGILKAGGAYVPLDPE 2762 Query: 348 LPAQRVDYILKDSQAGQILTVQSL--SLPPGTGESCEVIFLDDPM--LEQYSSSNLEHVI 403 P +R+ +IL+D+Q +LT Q L SLP VI LD + Q S SN + Sbjct: 2763 YPTERLQFILEDAQVSVLLTQQQLVNSLP---KHQARVICLDSDWEKIAQKSESNSLNTT 2819 Query: 404 HPHDLAYIIYTSGTTGNPKGVMIEHRNVVRLFFHEHNRFDFTCQDTWTLFHSFGFDFSVW 463 +LAY+IYTSG+TG PKGV++ H NVVRLF ++ + F QD WTLFHS+ FDFSVW Sbjct: 2820 TSDNLAYVIYTSGSTGKPKGVLVNHSNVVRLFEATNSWYSFNAQDVWTLFHSYAFDFSVW 2879 Query: 464 EIFXXXXXXXXXXXXXXXXXRDYRHIVQELRNEHVTVFNQTPSSFYQFMQ-EELEDTGEK 522 EI+ R + L E VT+ NQTPS+F Q +Q E+ T Sbjct: 2880 EIWGALLYGGRLVVVPYLVTRSPESFFELLTQEKVTILNQTPSAFRQLIQAEQSTATTGN 2939 Query: 523 LRLRYVILGGEALQPGKLEAWKVKYPGT--RIINMYGITETTVHTTFKEIGTEQIQANQN 580 L LR VI GGEAL+ L+ W ++ +++NMYGITETTVH T++ + + + + Sbjct: 2940 LNLRLVIFGGEALELKSLQPWFERHGDQLPQLVNMYGITETTVHVTYRPLSKADLNSTAS 2999 Query: 581 NIGVPFSTVEVYIFNRQHEQVPIXXXXXXXXXXXXXXXXYLNRTELTEDRFQTRRMGDRW 640 IG P ++VY+ + + VPI YLNR ELT RF + + Sbjct: 3000 VIGRPIRDLQVYVLDEYKQPVPIGVPGEMYVGGAGVARGYLNRPELTAQRFISSPFDNS- 3058 Query: 641 IRLYRTGDLGRYLPSGELEYVGRRDNQVKIRGFRIELDEISAHLLTVESIKEAVVSAREI 700 +LY+TGDL RYLP+GELEY+GR D QVKIRGFRIEL EI A L ++ E+VV RE Sbjct: 3059 -KLYKTGDLARYLPNGELEYLGRIDQQVKIRGFRIELGEIEALLAQHPAVWESVVVIRED 3117 Query: 701 EPNAQILVAYVVIKEGQEAAFDPVEIRQYLQTRISDYMIPSVLLPLSKIPLTLNGKVDYE 760 E + + LVAYVV K Q + E+RQ+L ++ YM+P+ + L +PLT NGK+D Sbjct: 3118 ELDDKRLVAYVVPKVKQSST--AAELRQFLANQLPSYMVPNTFMMLESLPLTSNGKIDRR 3175 Query: 761 KLDTLELKQQAKGVLTPPTTEMEHRIAEIWKTSLRMDRIGVHSTIFDLGGTSFDVITISK 820 L EL P T +E +A+IW L+++++G++ F+LGG S + Sbjct: 3176 ALPKPELDSTLLEKFVAPRTPIEDMLAQIWAQVLKVEQVGIYDNFFELGGHSLLATQLLS 3235 Query: 821 ALSEELGQEVPVITLFTYPTISMLAK 846 + E+P+ +LF T++ LA+ Sbjct: 3236 RIRNTFKVELPLRSLFAAATVAELAQ 3261 Score = 392 bits (1006), Expect = e-107, Method: Compositional matrix adjust. Identities = 273/871 (31%), Positives = 435/871 (49%), Gaps = 54/871 (6%) Query: 13 NDVYKKEQQYWLHKLAGLPDKSHFPCEPHKDRHQERHIETIPFSLDPVHARKLVQISNDS 72 DV + + YW +L P P + + Q F+L + L+Q+S + Sbjct: 3470 GDVLQTQLNYWQQQLKDAPALLVLPTDRPRPAVQTFAGTHQKFALSEKLTQGLIQLSKEQ 3529 Query: 73 DARLHVLLLAFTSVWLLKYSGQTDIVLGTSIYRQPSEED------FINTVLPVRVQVQNE 126 L + LLA L +Y+GQ DI++G+ I + E F+NT++ +R + Sbjct: 3530 GVTLFMTLLATYDTLLYRYTGQADILVGSPIANRDRNEIEGLIGFFVNTLV-MRTNLAGN 3588 Query: 127 MRLIDLISLMKQTVSEAARHQNYPFELMLK--QAGLDSGFLDVSVIVSNIQD----EQYL 180 +L++ ++ EA HQN PFE++++ Q D + + ++ +Q+ E L Sbjct: 3589 PSFSELLTRVRFMAMEAYTHQNLPFEMLVETLQPQRDLSYTPLFQVMFALQNAPMSEVEL 3648 Query: 181 SG----------TLSNFTMIVHREESV--LQGEIRFNAAVYSADTVNQLLEHFHVLLEQS 228 +G T + F + + + + L G ++ ++ A+T+ ++ HF LLE Sbjct: 3649 TGLSVSPLVVESTTAKFDLTLSMQNTADGLVGVWEYSTDLFDANTIERMTGHFVTLLEGI 3708 Query: 229 LADLHSSVQELSILTEKDRR-IIACSNATSAGFPEEATIPALFEECAAKYPNHTAAEFAD 287 +A+ + +L +LT+ +R+ ++ N T A +P + I LFEE A+ P+ A F + Sbjct: 3709 VANPEERISQLPMLTKIERQQLLVEWNDTQADYPYDKCIHQLFEEQVARTPDAVAVVFEN 3768 Query: 288 ERLSYQDLNRKANQAAHHLRRLGVTAESVVALILPPSLEMIIGILAVLKAGGAYLPIDPD 347 ++L+YQ LN +ANQ AH+L+ LGV +++V + + SLEM++G+L +LKAGGAY+P+DP Sbjct: 3769 QQLTYQQLNNRANQLAHYLQSLGVKPDTLVGICIERSLEMVVGLLGILKAGGAYVPLDPG 3828 Query: 348 LPAQRVDYILKDSQAGQILTVQSL--SLPPGTGESCEVIFLD---------DPMLEQYSS 396 P++R+ Y L D+Q +LT Q L LP +V++LD D Q+ Sbjct: 3829 YPSERLGYALSDAQISVLLTQQHLVEKLP---EHQAQVVYLDQNWDAILTADYAYAQFPK 3885 Query: 397 SNLEHVIHPHDLAYIIYTSGTTGNPKGVMIEHRNVVRLFFHEHNRFDFTCQDTWTLFHSF 456 N+ + P +LAY++YTSG+TG PKGV IEH + V L F S Sbjct: 3886 DNVHSQVQPTNLAYVLYTSGSTGKPKGVAIEHHSPVALVAWAKEVFTPEQLAGVLACTSI 3945 Query: 457 GFDFSVWEIFXXXXXXXXXXXXXXXXXRDYRHIVQELRNEHVTVFNQTPSSFYQFMQEEL 516 FD SV+E+F + H+ E VT+ N PS + E + Sbjct: 3946 CFDLSVFELF-----VPLSWGRKVILAENALHLPTLPAAEQVTLINTVPS----VITELI 3996 Query: 517 EDTGEKLRLRYVILGGEALQPGKLEAWKVKYPGTRIINMYGITETTVHTTFKEIGTEQIQ 576 G + V L GE LQ ++ + I N+YG +E T ++TF I E+ Sbjct: 3997 RINGLPGGVSTVNLAGEPLQNQLVQQIYQQQIVKYIFNLYGPSEDTTYSTFALI--EKGT 4054 Query: 577 ANQNNIGVPFSTVEVYIFNRQHEQVPIXXXXXXXXXXXXXXXXYLNRTELTEDRFQTRRM 636 IG P + ++YI + + VP+ YLNR +LT ++F Sbjct: 4055 TFAPPIGRPIANTQIYILDEYLQPVPVGVAGELHIAGAGLARGYLNRPQLTIEKFIPNPF 4114 Query: 637 G-DRWIRLYRTGDLGRYLPSGELEYVGRRDNQVKIRGFRIELDEISAHLLTVESIKEAVV 695 D RLY+TGDL RYLP G +EY+GR DNQVKIRGFRIEL EI A L + ++ + V Sbjct: 4115 STDPHSRLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAVLSQLGDVQASCV 4174 Query: 696 SAREIEPNAQILVAYVVIKEGQEAAFDPVEIRQYLQTRISDYMIPSVLLPLSKIPLTLNG 755 ARE P + LVAYVV Q E+R L+ ++ +YM+P+ + L +PLT NG Sbjct: 4175 IAREDTPGDKRLVAYVVAD--QHCTTTISELRHSLKAKLPEYMVPNAFVVLESLPLTPNG 4232 Query: 756 KVDYEKLDTLELKQQAKGVLTPPTTEMEHRIAEIWKTSLRMDRIGVHSTIFDLGGTSFDV 815 KVD L T +L + P T +E +A+IW L+++++G++ F+LGG S Sbjct: 4233 KVDRHALPTPDLHSERIEKYVSPRTPIEEMLAQIWAQVLKVEQVGIYDNFFELGGHSLLA 4292 Query: 816 ITISKALSEELGQEVPVITLFTYPTISMLAK 846 + + E+P+ +LF T++ LA+ Sbjct: 4293 TQLLSRIRNTFKVELPLRSLFAAATVAELAQ 4323 Score = 383 bits (984), Expect = e-104, Method: Compositional matrix adjust. Identities = 277/878 (31%), Positives = 430/878 (48%), Gaps = 68/878 (7%) Query: 13 NDVYKKEQQYWLHKLAG------LP-DKSHFPCEPHKDRHQERHIETIPFSLDPVHARKL 65 +V + + YW KLAG LP D+ + + HQ+ TIP L ++ L Sbjct: 1342 GEVLESQLNYWQKKLAGVSTLLALPTDRPRPAFQSFRGSHQQI---TIPVEL----SQAL 1394 Query: 66 VQISNDSDARLHVLLLAFTSVWLLKYSGQTDIVLGTSIYRQPSEED------FINTVLPV 119 +S L + LLA L +Y+ DI +GT I + +E F+NT++ + Sbjct: 1395 RLLSRQQGVTLFMTLLAAFDTLLYRYTSSDDICVGTPIANRQHQEIEGLIGFFVNTLV-M 1453 Query: 120 RVQVQNEMRLIDLISLMKQTVSEAARHQNYPFELM---------LKQAGLDSGFLDVSVI 170 R + +L+S ++ EA HQ+ PFE + L L D+ + Sbjct: 1454 RTDLSGNPSFAELLSRVRSVALEAYTHQDIPFEQLVEALQPERSLSHTPLFQVMFDLQNV 1513 Query: 171 VSNIQDEQYLS---------GTLSNFTMIVHREESVLQGEIRFNAAVYSADTVNQLLEHF 221 + D LS T + T+ + + L G ++ ++ A T+ ++ HF Sbjct: 1514 PMSALDMTGLSMSSLTVETDTTKFDLTLSILETDLELVGVWEYDTDLFDAATITRMAGHF 1573 Query: 222 HVLLEQSLADLHSSVQELSILTEKDR-RIIACSNATSAGFPEEATIPALFEECAAKYPNH 280 +LLE +A+ + EL +L++ +R +++ N T A +P + I LFEE A+ P+ Sbjct: 1574 QLLLEGIVANPQQQLSELPLLSKPERNQLLVEWNDTQADYPYDKCIHQLFEEQVARTPDA 1633 Query: 281 TAAEFADERLSYQDLNRKANQAAHHLRRLGVTAESVVALILPPSLEMIIGILAVLKAGGA 340 A F +++L+YQ LN +ANQ AH+L+ LGV +++V + + SLEM++G+L +LKAGGA Sbjct: 1634 VAVVFENQQLTYQQLNNRANQLAHYLQSLGVKPDTLVGICIERSLEMVVGLLGILKAGGA 1693 Query: 341 YLPIDPDLPAQRVDYILKDSQAGQILTVQSL--SLPPGTGESCEVIFLD---------DP 389 Y+P+DP P++R+ Y L D+Q +LT Q L LP +V++LD D Sbjct: 1694 YVPLDPGYPSERLGYALSDAQISVLLTQQHLVEKLP---EHQAQVVYLDQNWDAILTADY 1750 Query: 390 MLEQYSSSNLEHVIHPHDLAYIIYTSGTTGNPKGVMIEHRNVVRLFFHEHNRFDFTCQDT 449 Q+ N+ + P +LAY++YTSG+TG PKGV IEH + V L F Sbjct: 1751 AYAQFPKDNVHSQVQPTNLAYVLYTSGSTGKPKGVAIEHHSPVALVAWAKEVFTPEQLAG 1810 Query: 450 WTLFHSFGFDFSVWEIFXXXXXXXXXXXXXXXXXRDYRHIVQELRNEHVTVFNQTPSSFY 509 S FD SV+E+F + H+ E VT+ N PS Sbjct: 1811 VLACTSICFDLSVFELF-----VPLSWGRKVILAENALHLPTLPAAEQVTLINTVPS--- 1862 Query: 510 QFMQEELEDTGEKLRLRYVILGGEALQPGKLEAWKVKYPGTRIINMYGITETTVHTTFKE 569 + E + G + V L GE LQ ++ + I N+YG +E T ++TF Sbjct: 1863 -VITELIRINGLPGGVSTVNLAGEPLQNQLVQQIYQQQIVKYIFNLYGPSEDTTYSTFAL 1921 Query: 570 IGTEQIQANQNNIGVPFSTVEVYIFNRQHEQVPIXXXXXXXXXXXXXXXXYLNRTELTED 629 I E+ IG P + ++YI + + VP+ YLNR +LT + Sbjct: 1922 I--EKGTTFAPPIGRPIANTQIYILDEYLQPVPVGVAGELHIAGAGLARGYLNRPQLTIE 1979 Query: 630 RFQTRRMG-DRWIRLYRTGDLGRYLPSGELEYVGRRDNQVKIRGFRIELDEISAHLLTVE 688 +F D RLY+TGDL RYLP G +EY+GR DNQVKIRGFRIEL EI A L + Sbjct: 1980 KFIPNPFSTDPHSRLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAVLSQLG 2039 Query: 689 SIKEAVVSAREIEPNAQILVAYVVIKEGQEAAFDPVEIRQYLQTRISDYMIPSVLLPLSK 748 ++ + V ARE P + LVAYVV Q E+R L+ ++ +YM+P+ + L Sbjct: 2040 DVQASCVIAREDTPGDKRLVAYVVAD--QHCTTTISELRHSLKAKLPEYMVPNAFVVLES 2097 Query: 749 IPLTLNGKVDYEKLDTLELKQQAKGVLTPPTTEMEHRIAEIWKTSLRMDRIGVHSTIFDL 808 +PLT NGKVD L T +L + P T +E +A+IW L+++++G++ F+L Sbjct: 2098 LPLTPNGKVDRHALPTPDLHSERIEKYVSPRTPIEEMLAQIWAQVLKVEQVGIYDNFFEL 2157 Query: 809 GGTSFDVITISKALSEELGQEVPVITLFTYPTISMLAK 846 GG S + + E+P+ +LF T++ LA+ Sbjct: 2158 GGHSLLATQLLSRIRNTFKVELPLRSLFAAATVAELAQ 2195 Score = 284 bits (726), Expect = 8e-75, Method: Compositional matrix adjust. Identities = 196/612 (32%), Positives = 309/612 (50%), Gaps = 34/612 (5%) Query: 275 AKYPNHTAAEFADER-LSYQDLNRKANQAAHHLRRLGVTAESVVALILPPSLEMIIGILA 333 A+ H+ A + ER L+Y++L R ANQ H L++LG S+VA+++ + + +L Sbjct: 543 AELRKHSPAVISPERVLTYEELWRLANQVGHRLQQLGAKPNSLVAVVISKGWKQVAAVLG 602 Query: 334 VLKAGGAYLPIDPDLPAQRVDYILKDSQAGQILTVQSLSLPPGTGESCEVIFLDDPMLEQ 393 VL +G AY+PIDP LP+QR +L+ SQA I+T L V+ +D+ M Q Sbjct: 603 VLMSGAAYVPIDPQLPSQRQQQLLEQSQARVIVTDDPLVATSAWVGLIPVMLIDERMQSQ 662 Query: 394 YSSSNLEHVIHPHDLAYIIYTSGTTGNPKGVMIEHRNVVRLFFHEHNRFDFTCQDTWTLF 453 + L V P DLAY+IYTSG+TG PKGV I+H + V ++RF + D Sbjct: 663 EPTLPLAWVQTPEDLAYVIYTSGSTGIPKGVAIDHCSAVNTLLDINSRFCVSPADRVLAL 722 Query: 454 HSFGFDFSVWEIFXXXXXXXXXXXXXXXXXRDYRHIVQELRNEHVTVFNQTPSSFYQFMQ 513 + FD SV++IF ++ H V+ +R HVT++N P+ Q + Sbjct: 723 SALNFDLSVYDIFGVLAAGGTIVMPGVTEVKEPAHWVELMRQHHVTLWNTVPA-LGQMLA 781 Query: 514 EEL--EDTGEKLRLRYVILGGEALQPGKLEA-WKVKYPGTRIINMYGITETTVHTTFKEI 570 + L E LR +L G+ L P L A + + I+++ G TE ++ + I Sbjct: 782 DYLSRERMTPPQGLRLALLSGDWL-PLSLPAQLRQLWSQMEIVSLGGATEASIWSICYPI 840 Query: 571 GTEQIQANQNNI--GVPFSTVEVYIFNRQHEQVPIXXXXXXXXXXXXXXXXYLNRTELTE 628 +++ + ++I G P +F+ + P+ Y E T Sbjct: 841 --DEVDPSWSSIPYGKPLVNQTFVVFDDRLNARPVWVPGELYIGGIGLARGYWQDEERTA 898 Query: 629 DRFQTRRMGDRWIRLYRTGDLGRYLPSGELEYVGRRDNQVKIRGFRIELDEISAHLLTVE 688 F T + RLY+TGDLGRYLP+G +E++GR D+Q+KIRGFRIEL EI + L Sbjct: 899 TSFITHPVTGE--RLYKTGDLGRYLPNGNIEFLGRLDHQIKIRGFRIELGEIESVLGQHP 956 Query: 689 SIKEAVVSAREIEPNAQILVAYVV-----IKEGQEAAFDPVE---------------IRQ 728 S+++ +V++ N Q LVAYVV DP+E +R+ Sbjct: 957 SVQQTLVTSVGESANRQ-LVAYVVPTIEHYPASPSEVHDPIEFKLSQPGWQQIRIAHLRE 1015 Query: 729 YLQTRISDYMIPSVLLPLSKIPLTLNGKVDYEKLDTLELKQQAKGVLTPPTTEMEHRIAE 788 +LQ ++ YM+PS + L +PLT NGKVD + L E++ K T +E + Sbjct: 1016 FLQEQLPAYMVPSHFVILEALPLTPNGKVDRKALPAPEMRSDQKLEFEAGRTPIEEMLTF 1075 Query: 789 IWKTSLRMDRIGVHSTIFDLGGTSFDVITISKALSEELGQEVPVITLFTYPTISMLAKVL 848 IW L++++IG+H F+LGG S + + + E+P+ +LF +PT++ LA+++ Sbjct: 1076 IWANILKVEQIGIHDNFFELGGNSLLATQVIAQVRSTISLEIPLRSLFQHPTVAKLAQII 1135 Query: 849 Q-ADSPVTELSA 859 Q A P +L+A Sbjct: 1136 QLAIQPDEQLTA 1147 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.136 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 1,203,225,821 Number of extensions: 48764754 Number of successful extensions: 147612 Number of sequences better than 1.0e-05: 1814 Number of HSP's gapped: 140114 Number of HSP's successfully gapped: 2813 Length of query: 882 Length of database: 757,237,578 Length adjustment: 135 Effective length of query: 747 Effective length of database: 390,699,213 Effective search space: 291852312111 Effective search space used: 291852312111 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 131 (55.1 bits)