BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0025.p (1943 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value sp|O68006|BACA_BACLI Bacitracin synthetase 1 (BA1) [Includes: AT... 1270 0.0 ref|ZP_00124460.1| COG1020: Non-ribosomal peptide synthetase mod... 1118 0.0 ref|ZP_00179483.1| hypothetical protein Cwat036301 [Crocosphaera... 1104 0.0 ref|NP_356935.1| AGR_L_2311p [Agrobacterium tumefaciens] >gi|179... 1036 0.0 sp|O30409|TYCC_BREPA Tyrocidine synthetase III [Includes: ATP-de... 970 0.0 >sp|O68006|BACA_BACLI Bacitracin synthetase 1 (BA1) [Includes: ATP-dependent isoleucine adenylase (IleA) (Isoleucine activase); ATP-dependent cysteine adenylase (CysA) (Cysteine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase); ATP-dependent glutamate adenylase (GluA) (Glutamate activase); ATP-dependent isoleucine adenylase (IleA) (Isoleucine activase); Glutamate racemase ] pir||T31677 bacitracin synthetase 1 - Bacillus licheniformis gb|AAC06346.1| bacitracin synthetase 1; BacA [Bacillus licheniformis] Length = 5255 Score = 1270 bits (3286), Expect = 0.0, Method: Compositional matrix adjust. Identities = 685/1709 (40%), Positives = 1012/1709 (59%), Gaps = 49/1709 (2%) Query: 248 VLKHPAQKTGLIHLPDNQETDRLLNRFNQTAGEYPEHLTVHQLFAARVKEHPHQAAVTFR 307 V KH + G+ H E + +L+ FN T +YP++ T+H+LF + + P A+ F Sbjct: 2 VAKHSLE-NGVFHKMTENEKELILH-FNNTKTDYPKNKTLHELFEEQAMKTPDHTALVFG 59 Query: 308 NQSITYDELNXXXXXXXXXXXXXGIGPDQIVALITTRSVDMXXXXXXXXXXXXXXXPIDP 367 Q +TY ELN GIG I A+I RS +M PIDP Sbjct: 60 AQRMTYRELNEKANQTARLLREKGIGRGSIAAIIADRSFEMIIGIIGILKAGGAYLPIDP 119 Query: 368 GLPANRIAYMLDDAGVQVILTN----TSVENQGNRIVLDMRSLGLDHGAPLPVPPVHSSR 423 P +RIA+ML D V+LT ++ + + + LD + D + P+ V+ S Sbjct: 120 ETPKDRIAFMLSDTKAAVLLTQGKAADGIDCEADIVQLDREAS--DGFSKEPLSSVNDSG 177 Query: 424 NLAYCMYTSGTTGLPKGILVEHRSLLNFFSAISDVLSFGKGETFLSLTTVSFDIFWLESI 483 + AY +YTSG+TG PKG++ H S++ ++ + + L L+ SFD + Sbjct: 178 DTAYIIYTSGSTGTPKGVITPHYSVIRVVQN-TNYIDITEDNVILQLSNYSFDGSVFDIF 236 Query: 484 LPLLAGYQLVIADELQQKDVHALLALVKQAEISVMQTTPSRXXXXXXXXXXXXXXXXXRY 543 LL G LV+ ++ +++ L + + + ++SVM T + R Sbjct: 237 GALLNGASLVMIEKEALLNINRLGSAINEEKVSVMFITTA--LFNMIADIHVDCLSNLRK 294 Query: 544 LLIGGEPLPQALAEQARSILPGGRIFNLYGPTETTIWSTAQEVT-----AGPVNIGKPLK 598 +L GGE + + + ++ ++YGPTE+T+++T + A + IG PL Sbjct: 295 ILFGGERASIPHVRKVLNHVGRDKLIHVYGPTESTVYATYYFINEIDDEAETIPIGSPLA 354 Query: 599 NTQVYILNDELLLQPIGVPGILYIGGHGVVRGYQNNPELTAQRFIDNPYRPGEQIYCTGD 658 NT V I+++ L PIGVPG L I G G+ +GY N ELTA++FI +P+ PGE++Y TGD Sbjct: 355 NTSVLIMDEAGKLVPIGVPGELCIAGDGLSKGYLNREELTAEKFIPHPFIPGERLYKTGD 414 Query: 659 IARWTEEGTIEYLGRADFQVKIRGYRIELAEIEQQLDTHPAIEKSVVRAQRDDQDEPMLV 718 +A+W +G IE++GR D QVKIRG+RIEL EIE +L+ H I +++V + D++ P + Sbjct: 415 LAKWLPDGNIEFIGRIDHQVKIRGFRIELGEIESRLEMHEDINETIVTVREDEESRPYIC 474 Query: 719 AYYTAARTVSGAELREFLLKFLPAYMIPQHFMEIGKIPLMISGKLDVKALPPVTVTLVQP 778 AY TA R +S EL+ FL + LP YMIP +F+++ K+PL +GK+D KALP T Sbjct: 475 AYITANREISLDELKGFLGEKLPEYMIPAYFVKLDKLPLTKNGKVDRKALPEPDRTAGAE 534 Query: 779 GETRKPQDEVEEKLLEIWKKVLRIGDTGVQDGFFEMGGNSIQIMQLVYEINKCFPVSFQF 838 E P++E EEKL +W+ VL + G+ D F +MGG+S+ M+L+ +I + V Sbjct: 535 NEYEAPRNETEEKLAAVWQDVLHVEKAGIHDHFAQMGGHSLHAMELIAKIKEKMNVEIPL 594 Query: 839 THFIERQTIERIADFIKEAIQEERKEELPFIAADPANRHEPFPLTNVQMAYYLGRSSHFE 898 + TI+ ++ FI+ QE++ + L AADP N HE FPLT +Q+AY +GR FE Sbjct: 595 HQLFKLATIKELSAFIEANHQEDKGDTLVTRAADPENIHEIFPLTGIQLAYLVGRDETFE 654 Query: 899 LGGVSTHSYLEMATELDIRRLNQCLNTLIQRHPALHTVYLPDATQQILPEVPEYTICEYD 958 +GGV+T+ +E ++D+ R L LI RHP L T+ + TQ+IL YTI D Sbjct: 655 IGGVATNLTVEFEADVDLNRFQLTLQKLIDRHPILRTIVFENGTQKILEATQRYTIETQD 714 Query: 959 LSGYTEEAKNKRITKERDRMSHHIFNPNVWPLFEIVAFRSSPEESLLCISFDLLIMDAYS 1018 L G+TEE N RI ++R++M+ I +P+VWPLFE+ F E+ ++ D LI D S Sbjct: 715 LRGFTEEEINVRILEQREKMTSKIIDPSVWPLFELKTFMLPGEKKYFFLNVDPLICDDSS 774 Query: 1019 LEILQEEIMALYADRSLQLEELSITFRDYLVGYQQMKSGKWYLEDKEYWLQKVEDFPLAP 1078 ++ L E LY + LQL L +FRDY++ K Y +D++YWL K++ FP AP Sbjct: 775 MKRLIREFKQLYENPGLQLPSLEYSFRDYVLASINFKQTSRYQKDQQYWLDKLDHFPSAP 834 Query: 1079 GLPLLTQPQHVKNPYFKRKSKHYSQQHWRQLKQISQNHNLTPSAVLCTVYAEVLANWSNQ 1138 LPL + P HV P FK+ S W +LK+ +++H+LTP++VLC YA +LA WS Q Sbjct: 835 ELPLKSDPAHVAKPSFKKFSTFLDGHTWNELKKKARHHHLTPTSVLCAAYAYILAYWSRQ 894 Query: 1139 PQFGLNLTLFNRLPLHSDVDKLIGDFTSLLLLEVRMNPN-DSFWEKAGNIQRVLMEALAH 1197 F +NLT+FNR+P H DV +IGDFTSL+LL++ N SFW A N+Q L+EAL H Sbjct: 895 NHFAINLTVFNRIPFHPDVKNMIGDFTSLMLLDIHAEENMSSFWRFALNVQDTLLEALEH 954 Query: 1198 RHFDGIDVMREISKRRALGNKALLPIVFTSALFDNGEDGGEAAENHGEASDGEQSTNGIT 1257 RH+DG+DV+R I+K+ + KA++PIVFTS L +N +D ++ D + T Sbjct: 955 RHYDGVDVIRNIAKKNGMNKKAVMPIVFTSVLSENPDDSFDS------LVDFDNIHFFST 1008 Query: 1258 QTSQVYLDNQVALIHGKMVINWDYISELFDPAVMDAMFAQYLSRIEAILYSREEMGFPAL 1317 +TSQVY+DNQV I+G + I WDY+ ++F+ V+++MF QY++ I+ + S E++ + Sbjct: 1009 RTSQVYIDNQVYEINGGLYITWDYVEQIFEHEVIESMFDQYIAVIQKAV-SGEDVSTIQM 1067 Query: 1318 PASDYTSIQAYNHTEEPIPSKTLHGLFEEAVHQTPYAVAIEADNLSITYKELDDRADKVA 1377 I AYN T++ +K LH LF V P +A++ + +TY+ELD+++++VA Sbjct: 1068 NEKSRQMISAYNDTDQSFDAKPLHELFTGQVKHGPDRMALKHHDEVMTYQELDEKSNQVA 1127 Query: 1378 GSLRSLGVSAGDRVGVIARKEIATFINILGILKSGAAYVPIDPEYPQERVDYIRNHSQCK 1437 L GV GD +GVI ++ + T +N+L +LK+GAAY+P+DP+YP+ER YI++ S CK Sbjct: 1128 RFLIGKGVEKGDYIGVIGKRSLGTIVNLLAVLKTGAAYIPLDPDYPEERKAYIQSKSNCK 1187 Query: 1438 LVLETDYYEK-NCRGQHPAELQRHNLPESLAYVIYTSGSTGNPKGVMISHQAACNTVQDI 1496 + D Y+K + A + R + +AYVI+TSGSTG PKGV I+H NT+ DI Sbjct: 1188 FFISHDVYDKEHIERFSKAPVDRKVDLDDMAYVIFTSGSTGKPKGVQITHVPQRNTILDI 1247 Query: 1497 NQKFQVGAADRMLGISSLCFDLSVYDIFGAFAAGATLVLVKDQKDIRQLADTLSAQKITI 1556 N+KF V D ++GISSLCFDLSVYD+FGA ++GA+LV++ DQ+D+ L +T ++ITI Sbjct: 1248 NEKFNVTEQDNIMGISSLCFDLSVYDVFGALSSGASLVIIDDQRDVFSLKETAEKERITI 1307 Query: 1557 WNSVPAIMDRVGSEIRAQGIYQE---NLDLRLVLLSGDWIPLHLPETVKQLFPAAKLISC 1613 WNSVPAIM +Y + N LRL+LLSGDWIPL LP T+K+ F A++IS Sbjct: 1308 WNSVPAIMGMTAD------VYPDNELNHHLRLILLSGDWIPLQLPATIKKTFKNAEVISL 1361 Query: 1614 GGATEASIWSIYYPIDEVMPQWTSIPYGMPLANQQFYVLNQQMDYCPLEVSGELYIGGSG 1673 GGATE SIWSIYYPI +V W SIPYG PLANQ+ YVLNQ CP+ V GELYIGG+G Sbjct: 1362 GGATEGSIWSIYYPIQKVEEDWKSIPYGKPLANQKIYVLNQNKQLCPVGVEGELYIGGAG 1421 Query: 1674 VANGYLNDPEKPSHSFIHHPELGYIYRTGDYGVLHRDGCIEFLGRKDQQVKVGGYRIELG 1733 VA+GY++D EK HSFI H ELGYIY+TGDYGVL DG +EFLGRKD QVK+ GYR+E+G Sbjct: 1422 VASGYIHDQEKTEHSFIQHQELGYIYKTGDYGVLKEDGYVEFLGRKDSQVKIRGYRVEMG 1481 Query: 1734 EVEAQLLRCGGVRHAVVLAADGED--KRLGAYLIPDSQSADQAAFINEVRARIAKVLPDY 1791 E+E L+ + A V+ D K L A+++ A+ A +V+ + K LPDY Sbjct: 1482 EIENTLVSHQEITKASVIDYTSPDGIKNLYAFVV-----AENAISQLDVKEFLQKTLPDY 1536 Query: 1792 MIPHYFVVLEQFPLTANGKMDVQALLKL---QPAGNKQTSAYTAPRNDVEERIVNIFKEL 1848 MIP FV +E+ PLT NGK+D + L L A Q P N+ + ++ I+K++ Sbjct: 1537 MIPAKFVQIEEIPLTVNGKVDKRTLHDLAEQHTADEGQRGGRMLPENETQAMLLEIWKDI 1596 Query: 1849 LEADQVGTLDNFFEMGINSVQIAMINNKLKQEFQKEIPLLTLFEYANIHALAGYLSGNDQ 1908 D + +++E+G +S++ I ++ + E+P+ +F+ I AL YL ++ Sbjct: 1597 FGLDSINLDVSYYEIGGDSLKAISIITEINKRMNVEMPISEIFKNDTIIALDHYLKNREE 1656 Query: 1909 NEPDDVPQEQQVTRNQGKERMKQRSAKRR 1937 ++ E + + + KE A++R Sbjct: 1657 SD-----MEHPIQKAREKEYYPTSPAQQR 1680 Score = 838 bits (2165), Expect = 0.0, Method: Compositional matrix adjust. Identities = 585/1957 (29%), Positives = 958/1957 (48%), Gaps = 129/1957 (6%) Query: 14 YWLETFSGEIPLLHLPADHSRPAFKTYRGSAEMFSIPKEQVLEIKQLAAEQEATLYMVLF 73 YWL+ + L P D+ R T+ GS+ + +E I++LA TLY V+ Sbjct: 1859 YWLDVYRDIPSKLDFPYDYKRHHIDTFEGSSVFLEMERELSDHIRKLAKHNGTTLYTVML 1918 Query: 74 AVWNILLAKLSDQEEIIVGVPTSGRNHSDIEHVIGMFVNTLPIKSRISAKLTFAEILHAM 133 + + +LL K ++Q +I+VG +GR H D++ V G+FVNTL +++ + +F E L Sbjct: 1919 SAYYVLLNKYTNQTDIVVGTAAAGRLHPDLQDVFGVFVNTLALRNEVDTSYSFKEFLQQT 1978 Query: 134 KANISNALEHQDYPFEDLVSQLQITRDFGRNPLFDVMFXXXXXXXXXXXXXXXXXXELQM 193 K A ++ +YPF+DL+ +L R+ RNPLFD MF ++++ Sbjct: 1979 KERTIAAFDNSEYPFDDLIRKLNGVRESNRNPLFDTMFVLEDARMFTKQKG-----DVKL 2033 Query: 194 KPYPYTTTTSRFDLTLDGEERAGELVFTLEYATDLFTRETVMRLIRYFRTILLEVLKHPA 253 P + ++FD+ + + ++V +EY+T LF ET+ ++ + IL EV ++ Sbjct: 2034 SPIIFELDNAKFDMIFNVLDFEQKIVLNIEYSTSLFKDETIQKIAEDYFRILEEVSENLD 2093 Query: 254 QKTGLIHLPDNQETDRLLNRFNQTAGEYPEHLTVHQLFAARVKEHPHQAAVTFRNQSITY 313 I + QE LL FN T YP+ +HQLF + K P AV F +Q +TY Sbjct: 2094 VALHQIDMISRQEKRTLLESFNHTKTAYPKGKAIHQLFEEQAKRIPDHTAVVFEDQKLTY 2153 Query: 314 DELNXXXXXXXXXXXXXGIGPDQIVALITTRSVDMXXXXXXXXXXXXXXXPIDPGLPANR 373 +LN G+ PD +V ++ RS DM PIDP P R Sbjct: 2154 RQLNEKANQVARLLREKGVKPDTLVGIMMERSSDMIAAILGVLKAGGAYLPIDPEYPPER 2213 Query: 374 IAYMLDDAGVQVILTNTSV--ENQGNRIVL----DMRSLGLDHGAPLPVPPVHSSRNLAY 427 + YM D+ V+VI+++ + E I L D R G D + V+ S +LAY Sbjct: 2214 MRYMAFDSEVKVIISDVPLAEELTAESIELIHMDDERIAGQDRS---DIDNVNQSGDLAY 2270 Query: 428 CMYTSGTTGLPKGILVEHRSLLNFFSAISDVLSFGKGETFLSLTTVSFDIFWLESILPLL 487 +YTSG+TG PKG+++EH+SL+N S G+ + ++SFD F E + Sbjct: 2271 VIYTSGSTGKPKGVMIEHQSLINLCSWHQSCFEVGQNDNSSIYASISFDAFVWELFPYIT 2330 Query: 488 AGYQLVIADELQQKDVHALLALVKQAEISV-MQTTPSRXXXXXXXXXXXXXXXXXRYLLI 546 AG + + ++ + DV L I++ TP R LL Sbjct: 2331 AGATVHVLNQETRLDVEKLNRYFHDHHITISFLPTP------VCEQFTALDNHSLRTLLT 2384 Query: 547 GGEPLPQALAEQARSILPGGRIFNLYGPTETTIWSTAQEVTAGPVNI--GKPLKNTQVYI 604 GG+ L E++ I+ N YGPTE T+ +T+ + NI GKP+ N +VYI Sbjct: 2385 GGDKL-NVFKEKSYQIV------NNYGPTENTVVATSFPIDKSHQNIPIGKPIDNVKVYI 2437 Query: 605 LNDELLLQPIGVPGILYIGGHGVVRGYQNNPELTAQRFIDNPYRPGEQIYCTGDIARWTE 664 LN +L L P+G G L I G G+ RGY N PELT ++FI NP+ PGE++Y TGD+A+ Sbjct: 2438 LNKDLQLCPLGASGELCIAGEGLARGYVNRPELTREKFIGNPFVPGERMYRTGDLAKMLP 2497 Query: 665 EGTIEYLGRADFQVKIRGYRIELAEIEQQLDTHPAIEKSVVRAQRDDQDEPMLVAYYTAA 724 +G I++LGR D QVKIRGYRIE EIE +L + IE++ V A+ D +P L AY T Sbjct: 2498 DGNIQFLGRVDQQVKIRGYRIEPGEIENRLLKYEKIEEAAVIAREDGDHDPYLCAYVTVK 2557 Query: 725 RTVSGAELREFLLKFLPAYMIPQHFMEIGKIPLMISGKLDVKALPPVTVTLVQPGETRKP 784 + V ++R FL K LP YMIPQ+F+++ +PL ++GK+D K+LP ++ P Sbjct: 2558 KEVEPEKIRAFLKKSLPDYMIPQYFVQLDGLPLTVNGKVDKKSLPVPERSVTMDRRYEAP 2617 Query: 785 QDEVEEKLLEIWKKVLRIGDTGVQDGFFEMGGNSIQIMQLVYEINKCFPVSFQFTHFIER 844 +D++EEKL+ IW++ L I G+ FFE GG+S++ LV I+K V E Sbjct: 2618 RDQMEEKLVSIWEEALGINKIGINSHFFEAGGHSLKAAALVSTIHKELNVKLPLRQIFET 2677 Query: 845 QTIERIADFIKEAIQEERKEELPFIAADPANRHEP-FPLTNVQMAYYLGRSSHFELGGVS 903 TI+ + D R+ + +I D +P + L++ Q Y+ L Sbjct: 2678 PTIKGLRDI------SVRRRKCFYI--DRKTEEKPYYRLSSAQKRLYI-------LSQTG 2722 Query: 904 THSYLEM------ATELDIRRLNQCLNTLIQRHPALHTVYL---PDATQQILPEVPEYTI 954 +H M + DIRR L +++RH + T ++ + QQI E+ ++ + Sbjct: 2723 SHVAYNMPFAMTLEGDFDIRRFENTLKNMVKRHESFRTSFVMIDGEVMQQIEKEI-DFQV 2781 Query: 955 CEYDLSGYTEEAKNKRITKERDRMSHHIFNPNVWPLFEIVAFRSSPEESLLCISFDLLIM 1014 D+ + E K K + F+ PL + + E LL +I Sbjct: 2782 AYSDIGKESAEEKIKSFIRP--------FHLEKAPLLRAEVVKLNEREHLLMFDMHHIIS 2833 Query: 1015 DAYSLEILQEEIMALYADRSLQLEELSITFRDYLVGYQQMKSGKWYLEDKEYWLQKVEDF 1074 D S +I +E+ ALY +SL+ I ++DY + +EYWL+ + Sbjct: 2834 DGVSTDIFIQELGALYEGKSLK--PFHIQYKDYAEWENSHARSEELKRQEEYWLKTYKG- 2890 Query: 1075 PLAPGLPLLTQPQHVKNPYFKRK-----SKHYSQQHWRQLKQISQNHNLTPSAVLCTVYA 1129 +P+L P K P K + + +R+L+ +++ + +T +L Y Sbjct: 2891 ----DIPVLDLPIDHKRPLTKSSEGDTVTAAIESETFRKLQHMAKENGVTMYMLLLAGYT 2946 Query: 1130 EVLANWSNQPQFGLNLTLFNRLPLHSDVDKLIGDFTSLLLLEVRMNPNDSFWEKAGNIQR 1189 +L+ ++ Q + R H D+ LIG F + L + +F + ++ Sbjct: 2947 ALLSKYTGQEDIIVGTPAAGR--NHEDIQHLIGMFVNTLAIRNHPEGKKTFRDYLQEVKE 3004 Query: 1190 VLMEALAHRHFDGIDVMREISKRRALGNKALLPIVFTSALFDNGEDGGEAAENHGEASDG 1249 ++A ++ + +++ +++ +R + P+ T ++ N + AE G S Sbjct: 3005 NTLQAYENQDYPFEELVEKVNIKRDMARN---PLFDTMLVYHNTDVKPFEAE--GLRSRL 3059 Query: 1250 EQSTNGITQTSQVYLDNQVALIHGKMVINWDYISELFDPAVMDAMFAQYLSRIEAILYSR 1309 + GI++ ++ A + + +Y + LF+ M+ + +S +E Sbjct: 3060 VEIKRGISKFDITVTASEAA---DGLRLEVEYSTTLFNKERMERLSEHLISLLEQAA-DH 3115 Query: 1310 EEMGFPAL----PASDYTSIQAYNHTEEPIPSK-TLHGLFEEAVHQTPYAVAIEADNLSI 1364 ++ + + + +N T+ + T+ LFE+ +TP A+ + +I Sbjct: 3116 PDIAINQIDVLTKGERHRVLYDFNRTDGVFCKEMTIPELFEKQAEKTPDHPAVAFGDETI 3175 Query: 1365 TYKELDDRADKVAGSLRSLGVSAGDRVGVIARKEIATFINILGILKSGAAYVPIDPEYPQ 1424 +Y+EL++RA+ +A +LR GV G++ + I + I+GILK+G AY+PIDP YPQ Sbjct: 3176 SYRELNERANSLAFTLRQKGVGPDVIAGILTERSIEMIVGIMGILKAGGAYLPIDPAYPQ 3235 Query: 1425 ERVDYIRNHSQCKLVLET-----------DYYEKNCRGQ--HPAELQRHNLPESLAYVIY 1471 ER+ YI S ++ D + GQ H L+ P+ LAYVIY Sbjct: 3236 ERISYIVKDSDVSVLCAAGDVDPGEAYTGDIIRIDQTGQNDHVENLKHDIKPQHLAYVIY 3295 Query: 1472 TSGSTGNPKGVMISHQAACNTVQDINQKF--QVGAADRMLGISSLCFDLSVYDIFGAFAA 1529 TSGSTG PKGVMI H + N V +N++ + A + ++ FD SV IF A Sbjct: 3296 TSGSTGKPKGVMIEHHSVNNLVHGLNERIYQHLDAHLNVALVAPYIFDASVKQIFAALLF 3355 Query: 1530 GATLVLVKDQK--DIRQLADTLSAQKITIWNSVPAIMDRVGSEIRAQGIYQENLDLRLVL 1587 G TL +V + D L + S I + + PA ++ + + + D++ ++ Sbjct: 3356 GHTLCIVPRETAWDAMSLIEYYSKNNINVSDMTPAHLNMLAYVDKT----ELEFDVKELI 3411 Query: 1588 LSGDWIPLHLPETVKQLFPAAKLISCG-----GATEASIWSIYYPIDE-VMPQWTSIPYG 1641 + GD + P+ + LF +SC G TE + + + I+ +PQ SIP G Sbjct: 3412 VGGDALT---PDVIGGLFHKFPNLSCNITNVYGPTECCVDAASHQIESGKVPQTPSIPIG 3468 Query: 1642 MPLANQQFYVLNQQMDYCPLEVSGELYIGGSGVANGYLNDPEKPSHSFIHHP-ELG-YIY 1699 PL N Y++++++ P+ ++GEL I G GVA GY+N PE + F+ HP E G +Y Sbjct: 3469 RPLLNTSIYIVDKELRPLPVGIAGELCIAGEGVARGYVNRPELTAEKFVDHPFEPGKKMY 3528 Query: 1700 RTGDYGVLHRDGCIEFLGRKDQQVKVGGYRIELGEVEAQLLRCGGVRHAVVLAADGEDKR 1759 +TGD + DG IEFLGR D QVK+ GYRIELGEVE QLL ++ A V+A G+D+ Sbjct: 3529 KTGDLAMWLPDGQIEFLGRADHQVKIRGYRIELGEVEQQLLTHEKIKEAAVIA--GKDQN 3586 Query: 1760 LGAYLIPDSQSADQAAFINEVRARIAKVLPDYMIPHYFVVLEQFPLTANGKMDVQALLKL 1819 +YL ++D+ +VR + + +PDYMIP YFV L++ P T +GK+D AL + Sbjct: 3587 GNSYLCA-YIASDKELPAADVRQFLEREMPDYMIPSYFVKLDRLPRTPSGKVDRSALPEA 3645 Query: 1820 QPAGN-KQTSAYTAPRNDVEERIVNIFKELLEADQVGTLDNFFEMGINSVQIAMINNKLK 1878 N + + Y PRN++E ++V +++E+L A+ +G +FF G +S++ I ++L Sbjct: 3646 DGNVNVMEGTGYDPPRNEIERKLVQVWREILGAEDIGISHHFFAAGGDSIKALQIVSRLA 3705 Query: 1879 QEFQKEIPLLTLFEYANIHALAGYLSGNDQNEPDDVP 1915 + ++ + LF I L+ +++ ++ + P Sbjct: 3706 K-MNLKLEMKALFANPKIKDLSRFITEETRHRKHNKP 3741 Score = 669 bits (1726), Expect = 0.0, Method: Compositional matrix adjust. Identities = 522/1945 (26%), Positives = 899/1945 (46%), Gaps = 142/1945 (7%) Query: 14 YWLETF-----SGEIPLLHLPADHSRPAFKTYRGSAEMFSIPKEQVLEIKQLAAEQEATL 68 YWL+ + E+PL PA ++P+FK + + + E+K+ A T Sbjct: 822 YWLDKLDHFPSAPELPLKSDPAHVAKPSFKKFSTFLDGHTWN-----ELKKKARHHHLTP 876 Query: 69 YMVLFAVWNILLAKLSDQEEIIVGVPTSGR--NHSDIEHVIGMFVNTLPIKSRISAKLT- 125 VL A + +LA S Q + + R H D++++IG F + + + ++ Sbjct: 877 TSVLCAAYAYILAYWSRQNHFAINLTVFNRIPFHPDVKNMIGDFTSLMLLDIHAEENMSS 936 Query: 126 FAEILHAMKANISNALEHQDYPFEDLVSQLQITRDFGRNPLFDVMFXXXXXXXXXXXXXX 185 F ++ + ALEH+ Y D++ + + + ++F Sbjct: 937 FWRFALNVQDTLLEALEHRHYDGVDVIRNIAKKNGMNKKAVMPIVFTSVLSENPDDSFDS 996 Query: 186 XXXXELQMKPYPYTTTTSRFDLTLDGEERAGELVFTLEYATDLFTRETVMRLIRYFRTIL 245 + + ++T TS+ + E G L T +Y +F E + + + ++ Sbjct: 997 LVDFD---NIHFFSTRTSQVYIDNQVYEINGGLYITWDYVEQIFEHEVIESMFDQYIAVI 1053 Query: 246 LEVLKHPAQKTGLIHLPDNQETDRLLNRFNQTAGEYPEHLTVHQLFAARVKEHPHQAAVT 305 + + + I + N+++ ++++ +N T + + +H+LF +VK P + A+ Sbjct: 1054 QKAVS--GEDVSTIQM--NEKSRQMISAYNDTDQSF-DAKPLHELFTGQVKHGPDRMALK 1108 Query: 306 FRNQSITYDELNXXXXXXXXXXXXXGIGPDQIVALITTRSVDMXXXXXXXXXXXXXXXPI 365 ++ +TY EL+ G+ + +I RS+ P+ Sbjct: 1109 HHDEVMTYQELDEKSNQVARFLIGKGVEKGDYIGVIGKRSLGTIVNLLAVLKTGAAYIPL 1168 Query: 366 DPGLPANRIAYMLDDAGVQVILTNTSVENQGNRIVLDMRSLGLDHGAPLPVPPVHSSRNL 425 DP P R AY+ + + +++ + + ++ + PV ++ Sbjct: 1169 DPDYPEERKAYIQSKSNCKFFISHDVYDKEH-----------IERFSKAPVDRKVDLDDM 1217 Query: 426 AYCMYTSGTTGLPKGILVEHRSLLNFFSAISDVLSFGKGETFLSLTTVSFDIFWLESILP 485 AY ++TSG+TG PKG+ + H N I++ + + + + ++++ FD+ + Sbjct: 1218 AYVIFTSGSTGKPKGVQITHVPQRNTILDINEKFNVTEQDNIMGISSLCFDLSVYDVFGA 1277 Query: 486 LLAGYQLVIADELQQKDVHALLALVKQAEISVMQTTPSRXXXXXXXXXXXXXXXXXRYLL 545 L +G LVI D+ Q+DV +L ++ I++ + P+ R +L Sbjct: 1278 LSSGASLVIIDD--QRDVFSLKETAEKERITIWNSVPAIMGMTADVYPDNELNHHLRLIL 1335 Query: 546 IGGEPLPQALAEQARSILPGGRIFNLYGPTETTIWST---AQEVTAGPVNI--GKPLKNT 600 + G+ +P L + + +L G TE +IWS Q+V +I GKPL N Sbjct: 1336 LSGDWIPLQLPATIKKTFKNAEVISLGGATEGSIWSIYYPIQKVEEDWKSIPYGKPLANQ 1395 Query: 601 QVYILNDELLLQPIGVPGILYIGGHGVVRGYQNNPELTAQRFIDNPYRPGEQIYCTGDIA 660 ++Y+LN L P+GV G LYIGG GV GY ++ E T FI ++ IY TGD Sbjct: 1396 KIYVLNQNKQLCPVGVEGELYIGGAGVASGYIHDQEKTEHSFIQ--HQELGYIYKTGDYG 1453 Query: 661 RWTEEGTIEYLGRADFQVKIRGYRIELAEIEQQLDTHPAIEKSVVRAQRDDQDEPMLVAY 720 E+G +E+LGR D QVKIRGYR+E+ EIE L +H I K+ V L A+ Sbjct: 1454 VLKEDGYVEFLGRKDSQVKIRGYRVEMGEIENTLVSHQEITKASVIDYTSPDGIKNLYAF 1513 Query: 721 YTAARTVSGAELREFLLKFLPAYMIPQHFMEIGKIPLMISGKLDVKALPPV----TVTLV 776 A +S +++EFL K LP YMIP F++I +IPL ++GK+D + L + T Sbjct: 1514 VVAENAISQLDVKEFLQKTLPDYMIPAKFVQIEEIPLTVNGKVDKRTLHDLAEQHTADEG 1573 Query: 777 QPGETRKPQDEVEEKLLEIWKKVLRIGDTGVQDGFFEMGGNSIQIMQLVYEINKCFPVSF 836 Q G P++E + LLEIWK + + + ++E+GG+S++ + ++ EINK V Sbjct: 1574 QRGGRMLPENETQAMLLEIWKDIFGLDSINLDVSYYEIGGDSLKAISIITEINKRMNVEM 1633 Query: 837 QFTHFIERQTIERIADFIKEAIQEERKEELPFIAADPANRHEPFPLTNVQMAYYLGRSSH 896 + + TI + ++K +EE E P A E +P + Q Y+ Sbjct: 1634 PISEIFKNDTIIALDHYLKN--REESDMEHPI---QKAREKEYYPTSPAQQRMYMLSMLE 1688 Query: 897 FELGGVSTHSYLEMATELDIRRLNQCLNTLIQRHPALHT---VYLPDATQQILPEVPEYT 953 E G L + ++ +L L T +QRH L T + + Q+I V Sbjct: 1689 NERGAYHIPMALLVEGRINAMQLENALKTFLQRHEILRTGFEIQNNELIQKIYENVDFRL 1748 Query: 954 ICEYDLSGYTEEAKNKRITKERDRMSHHIFNPNVWPLFEIVAFRSSPEESLLCISFDLLI 1013 E + T++ IT + S F+ + PL + +L I+F +I Sbjct: 1749 EYECLDASITDQHALMEITSRYCKESIKPFDLSRPPLMRAKLIKIDDIRHILVINFHHII 1808 Query: 1014 MDAYSLEILQEEIMALYADRSLQLEELSITFRDYLVGYQQMKSGKWYLEDKEYWLQKVED 1073 D S IL EI+ LY++ + L E+++ ++DY+ + + YWL D Sbjct: 1809 SDGVSQGILMNEILELYSN--VPLPEVNVQYKDYVEWNHTFNQSAAMKKQEAYWLDVYRD 1866 Query: 1074 FPLAPGLPLLTQPQHVKNPYFKRKSKHYSQQHWRQLKQISQNHNLTPSAVLCTVYAEVLA 1133 P P + H+ ++ ++++++++ T V+ + Y +L Sbjct: 1867 IPSKLDFPYDYKRHHIDTFEGSSVFLEMERELSDHIRKLAKHNGTTLYTVMLSAYYVLLN 1926 Query: 1134 NWSNQPQFGLNLTLFNRLPLHSDVDKLIGDFTSLLLLEVRMNPNDSFWEKAGNIQRVLME 1193 ++NQ + R LH D+ + G F + L L ++ + SF E + + Sbjct: 1927 KYTNQTDIVVGTAAAGR--LHPDLQDVFGVFVNTLALRNEVDTSYSFKEFLQQTKERTIA 1984 Query: 1194 ALAHRHFDGIDVMREISKRRALGNKALLPIVFTSALFDNGEDGGEAAENHGEASDGEQST 1253 A + + D++R+++ R L +F ED + G+ + + Sbjct: 1985 AFDNSEYPFDDLIRKLNGVRESNRNPLFDTMFVL------EDARMFTKQKGDV----KLS 2034 Query: 1254 NGITQTSQVYLDN--QVALIHGKMVINWDYISELFDPAVMDAMFAQYLSRIEAI------ 1305 I + D V K+V+N +Y + LF + + Y +E + Sbjct: 2035 PIIFELDNAKFDMIFNVLDFEQKIVLNIEYSTSLFKDETIQKIAEDYFRILEEVSENLDV 2094 Query: 1306 ------LYSREEMGFPALPASDYTSIQAYNHTEEPIPS-KTLHGLFEEAVHQTPYAVAIE 1358 + SR+E T ++++NHT+ P K +H LFEE + P A+ Sbjct: 2095 ALHQIDMISRQE---------KRTLLESFNHTKTAYPKGKAIHQLFEEQAKRIPDHTAVV 2145 Query: 1359 ADNLSITYKELDDRADKVAGSLRSLGVSAGDRVGVIARKEIATFINILGILKSGAAYVPI 1418 ++ +TY++L+++A++VA LR GV VG++ + ILG+LK+G AY+PI Sbjct: 2146 FEDQKLTYRQLNEKANQVARLLREKGVKPDTLVGIMMERSSDMIAAILGVLKAGGAYLPI 2205 Query: 1419 DPEYPQERVDYIRNHSQCKLVLE---------------TDYYEKNCRGQHPAELQRHNLP 1463 DPEYP ER+ Y+ S+ K+++ ++ GQ +++ N Sbjct: 2206 DPEYPPERMRYMAFDSEVKVIISDVPLAEELTAESIELIHMDDERIAGQDRSDIDNVNQS 2265 Query: 1464 ESLAYVIYTSGSTGNPKGVMISHQAACNTVQDINQKFQVGAADRMLGISSLCFDLSVYDI 1523 LAYVIYTSGSTG PKGVMI HQ+ N F+VG D +S+ FD V+++ Sbjct: 2266 GDLAYVIYTSGSTGKPKGVMIEHQSLINLCSWHQSCFEVGQNDNSSIYASISFDAFVWEL 2325 Query: 1524 FGAFAAGATLVLVKDQK--DIRQLADTLSAQKITIWNSVPAIMDRVGSEIRAQGIYQENL 1581 F AGAT+ ++ + D+ +L ITI + +P + + Q +N Sbjct: 2326 FPYITAGATVHVLNQETRLDVEKLNRYFHDHHITI-SFLP-------TPVCEQFTALDNH 2377 Query: 1582 DLRLVLLSGDWIPLHLPETVKQLFPAAKLISCGGATEASIWSIYYPIDEVMPQWTSIPYG 1641 LR +L GD + + ++ ++++ G TE ++ + +PID+ +IP G Sbjct: 2378 SLRTLLTGGDKLNVFKEKSY-------QIVNNYGPTENTVVATSFPIDK---SHQNIPIG 2427 Query: 1642 MPLANQQFYVLNQQMDYCPLEVSGELYIGGSGVANGYLNDPEKPSHSFIHHPEL--GYIY 1699 P+ N + Y+LN+ + CPL SGEL I G G+A GY+N PE FI +P + +Y Sbjct: 2428 KPIDNVKVYILNKDLQLCPLGASGELCIAGEGLARGYVNRPELTREKFIGNPFVPGERMY 2487 Query: 1700 RTGDYGVLHRDGCIEFLGRKDQQVKVGGYRIELGEVEAQLLRCGGVRHAVVLA-ADGE-D 1757 RTGD + DG I+FLGR DQQVK+ GYRIE GE+E +LL+ + A V+A DG+ D Sbjct: 2488 RTGDLAKMLPDGNIQFLGRVDQQVKIRGYRIEPGEIENRLLKYEKIEEAAVIAREDGDHD 2547 Query: 1758 KRLGAYLIPDSQSADQAAFINEVRARIAKVLPDYMIPHYFVVLEQFPLTANGKMDVQALL 1817 L AY+ + + ++RA + K LPDYMIP YFV L+ PLT NGK+D ++L Sbjct: 2548 PYLCAYVTVKKEVEPE-----KIRAFLKKSLPDYMIPQYFVQLDGLPLTVNGKVDKKSL- 2601 Query: 1818 KLQPAGNKQTSA---YTAPRNDVEERIVNIFKELLEADQVGTLDNFFEMGINSVQIAMIN 1874 P + + Y APR+ +EE++V+I++E L +++G +FFE G +S++ A + Sbjct: 2602 ---PVPERSVTMDRRYEAPRDQMEEKLVSIWEEALGINKIGINSHFFEAGGHSLKAAALV 2658 Query: 1875 NKLKQEFQKEIPLLTLFEYANIHAL 1899 + + +E ++PL +FE I L Sbjct: 2659 STIHKELNVKLPLRQIFETPTIKGL 2683 Score = 426 bits (1094), Expect = e-117, Method: Compositional matrix adjust. Identities = 267/867 (30%), Positives = 440/867 (50%), Gaps = 26/867 (2%) Query: 14 YWLETFSGEIPLLHLPADHSRPAFKTYRGSAEMFSIPKEQVLEIKQLAAEQEATLYMVLF 73 YW + G LPA + + Y G ++ S KE +I ++A + T+ VL Sbjct: 4398 YWKDYLKGYESRSELPAFNRGATSEEYCGKEKVISFSKELTTKITRIAKQHHVTINTVLQ 4457 Query: 74 AVWNILLAKLSDQEEIIVGVPTSGRNH--SDIEHVIGMFVNTLPIKSRISAKLTFAEILH 131 +W ++LAK + +E++ G SGR IE ++G+F++T+P + +F E+L Sbjct: 4458 GIWGMILAKYKNTDEVVFGTVVSGREAPVDGIEEMVGLFIHTIPTRISFEGARSFKEVLK 4517 Query: 132 AMKANISNALEHQDYPFEDLVSQLQITRDFGRNPLFDVMFXXXXXXXXXXXXXXXXXXEL 191 +A ++E Y + +L S++Q+ + R + VM Sbjct: 4518 KTQAE---SIESNRYSYMNL-SEIQVLSEMKRELITHVMAFQNYAFDEELFRSQSGETGF 4573 Query: 192 QMKPYPYTTTTSRFDLTLDGEERAGELVFTLEYATDLFTRETVMRLIRYFRTILLEVLKH 251 +++ + + ++ L G +L L + +++ + L ++ T+ +V + Sbjct: 4574 ELEGV-HGKERTNYNFNLTGVLEDEQLKLKLTFNENVYDNTIIETLEKHIITVAEQVAED 4632 Query: 252 PAQKTGLIHLPDNQETDRLLNRFNQTAGEYPEHLTVHQLFAARVKEHPHQAAVTFRNQSI 311 Q I+L +E R+L+ FN T YP+ +H+LF + + P A+ F Q + Sbjct: 4633 ETQTLRDINLVSKEEQHRILHTFNDTKTGYPKDKPLHELFEEQAMKTPDHTALVFGAQRM 4692 Query: 312 TYDELNXXXXXXXXXXXXXGIGPDQIVALITTRSVDMXXXXXXXXXXXXXXXPIDPGLPA 371 TY ELN GIG I A+I RS +M PIDP P Sbjct: 4693 TYRELNEKANQTARLLREKGIGRGSIAAIIADRSFEMIIGIIGILKAGGTYLPIDPETPR 4752 Query: 372 NRIAYMLDDAGVQVILTNTSVENQGNRIVLDMRSLGLDHGAPLPVPPVHSSRNLAYCMYT 431 +RI YML ++G +++T S+ + +D+ S L + +P V+ S + AY +YT Sbjct: 4753 DRIDYMLKNSGAALLVTTDSLLKPFDIKTVDLCSDELHLLSEENLPRVNRSSDTAYIVYT 4812 Query: 432 SGTTGLPKGILVEHRSLLNFFSAISDVLSFGKGETFLSLTTVSFDIFWLESILPLLAGYQ 491 SG+TG PKG+++ H S ++ + + L L+ SFD + LL G Sbjct: 4813 SGSTGTPKGVVIPHYSAARVVKN-TNYIDITGNDVILQLSNYSFDGSVFDIFGALLNGAS 4871 Query: 492 LVIADELQQKDVHALLALVKQAEISVMQTTPSRXXXXXXXXXXXXXXXXXRYLLIGGEPL 551 LV+ ++ + H L ++K+ ++SVM T + R +L GGE Sbjct: 4872 LVLIEKETVLNTHELAEVIKKEQVSVMFITTA--LFNTLADINIGCLAKLRKILFGGE-- 4927 Query: 552 PQALAEQARSILPG---GRIFNLYGPTETTIWSTAQEVT-----AGPVNIGKPLKNTQVY 603 +A R +L ++ ++YGPTE+T+++T + A + IG PL NT V Sbjct: 4928 -RASIPHVRKVLDHVGRDKLIHVYGPTESTVYATYYFINEIDDEAETIPIGSPLANTSVL 4986 Query: 604 ILNDELLLQPIGVPGILYIGGHGVVRGYQNNPELTAQRFIDNPYRPGEQIYCTGDIARWT 663 I+++ L PIGVPG L I G G+ +GY N ELTA++FI +P+ PGE++Y TGD+A+W Sbjct: 4987 IMDEAGKLLPIGVPGELCIAGDGLSKGYLNREELTAEKFIPHPFIPGERLYKTGDLAKWL 5046 Query: 664 EEGTIEYLGRADFQVKIRGYRIELAEIEQQLDTHPAIEKSVVRAQRDDQDEPMLVAYYTA 723 +G IE++GR D QVKIRG+RIEL EIE +L+ H I +++V + D++ P + AY TA Sbjct: 5047 PDGNIEFIGRIDHQVKIRGFRIELGEIESRLEMHEDINETIVTVREDEESRPYICAYITA 5106 Query: 724 ARTVSGAELREFLLKFLPAYMIPQHFMEIGKIPLMISGKLDVKALPPVTVTLVQPGETRK 783 R +S EL+ FL + LP YMIP +F+++ K+PL +GK+D KALP + E Sbjct: 5107 NREISLDELKGFLGEKLPDYMIPAYFVKMDKLPLTKNGKVDRKALPEPDRSAGTEAEYEA 5166 Query: 784 PQDEVEEKLLEIWKKVLRIGDTGVQDGFFEMGGNSIQIMQLVYEINKCFPVSFQFTHFIE 843 P++ VE++++ I + VL G+ FF+ GGNS++ MQ V+ INK F + + + F + Sbjct: 5167 PRNYVEQRIISILEDVLGTERMGISCHFFDKGGNSLKAMQAVHSINKTFGIDMRISTFFK 5226 Query: 844 RQTIERIADFI-----KEAIQEERKEE 865 T + +A F+ + A+ EE EE Sbjct: 5227 HPTAKSLARFVLTAEAESAVSEEYAEE 5253 Score = 377 bits (967), Expect = e-102, Method: Compositional matrix adjust. Identities = 291/1072 (27%), Positives = 515/1072 (48%), Gaps = 92/1072 (8%) Query: 880 FPLTNVQMAYYLGRSSHFELGGVSTHSYLEMATELDIRRLNQCLNTLIQRHPALHTVYLP 939 +PL N+Q + G +++ + L + + +++RH L + Sbjct: 4210 YPLANMQKGMLFHNAMDQTSGAYFQQIVIKLKGRVHPDILEESFHEIVKRHEILRASFEY 4269 Query: 940 DAT---QQILPEVPEYTICEYDLSGYTEEAKNKRITKERDRMSHHIFNPNVWPLFEIVAF 996 + T +QI+ + DL+G +++ I F+ + L + Sbjct: 4270 EITAEPRQIIARDRKTPFTSIDLTGENRTRQHRFIETYLKEDQEKGFDLSSEALMRVCLI 4329 Query: 997 RSSPEESLLCISFDLLIMDAYSLEILQEEIMALYAD----RSLQLEELSITFRDYLVGYQ 1052 + S E L S +++D + L I+ E+ +LY S +L+E + DY+ Sbjct: 4330 KMSDESYRLIWSHHHILLDGWCLGIVLSELFSLYGKIMKGESRRLKEPK-PYGDYI---- 4384 Query: 1053 QMKSGKWY-LEDKE----YWLQKVEDFPLAPGLPLLTQPQHVKNPYFKRKSKHYSQQHWR 1107 KW +D+E YW ++ + LP + + K K +S++ Sbjct: 4385 -----KWLEKQDQEEAVAYWKDYLKGYESRSELPAFNRGATSEEYCGKEKVISFSKELTT 4439 Query: 1108 QLKQISQNHNLTPSAVLCTVYAEVLANWSNQPQFGLNLTLFNRLPLHSDVDKLIGDFTSL 1167 ++ +I++ H++T + VL ++ +LA + N + + R +++++G F Sbjct: 4440 KITRIAKQHHVTINTVLQGIWGMILAKYKNTDEVVFGTVVSGREAPVDGIEEMVGLFIHT 4499 Query: 1168 LLLEVRMNPNDSFWEKAGNIQRVLMEA--LAHRHFDGIDVMREISKRRALGNKALLPIVF 1225 + + SF E Q +E+ ++ + I V+ E+ + A F Sbjct: 4500 IPTRISFEGARSFKEVLKKTQAESIESNRYSYMNLSEIQVLSEMKRELITHVMAFQNYAF 4559 Query: 1226 TSALF--DNGEDGGEAAENHGEASDGEQSTNGITQTSQVYLDNQVALIHGKMVINWDYIS 1283 LF +GE G E E G++ TN + V D Q+ L K+ N Sbjct: 4560 DEELFRSQSGETGFEL-----EGVHGKERTNYNFNLTGVLEDEQLKL---KLTFN----E 4607 Query: 1284 ELFDPAVMDAMFAQYLSRIEAI------------LYSREEMGFPALPASDYTSIQAYNHT 1331 ++D +++ + ++ E + L S+EE + + +N T Sbjct: 4608 NVYDNTIIETLEKHIITVAEQVAEDETQTLRDINLVSKEEQ---------HRILHTFNDT 4658 Query: 1332 EEPIPS-KTLHGLFEEAVHQTPYAVAIEADNLSITYKELDDRADKVAGSLRSLGVSAGDR 1390 + P K LH LFEE +TP A+ +TY+EL+++A++ A LR G+ G Sbjct: 4659 KTGYPKDKPLHELFEEQAMKTPDHTALVFGAQRMTYRELNEKANQTARLLREKGIGRGSI 4718 Query: 1391 VGVIARKEIATFINILGILKSGAAYVPIDPEYPQERVDYIRNHSQCKLVLETDYYEKN-- 1448 +IA + I I+GILK+G Y+PIDPE P++R+DY+ +S L++ TD K Sbjct: 4719 AAIIADRSFEMIIGIIGILKAGGTYLPIDPETPRDRIDYMLKNSGAALLVTTDSLLKPFD 4778 Query: 1449 ------CRGQ----HPAELQRHNLPESLAYVIYTSGSTGNPKGVMISHQAACNTVQDINQ 1498 C + L R N AY++YTSGSTG PKGV+I H +A V++ N Sbjct: 4779 IKTVDLCSDELHLLSEENLPRVNRSSDTAYIVYTSGSTGTPKGVVIPHYSAARVVKNTNY 4838 Query: 1499 KFQVGAADRMLGISSLCFDLSVYDIFGAFAAGATLVLVKDQK--DIRQLADTLSAQKITI 1556 + D +L +S+ FD SV+DIFGA GA+LVL++ + + +LA+ + +++++ Sbjct: 4839 -IDITGNDVILQLSNYSFDGSVFDIFGALLNGASLVLIEKETVLNTHELAEVIKKEQVSV 4897 Query: 1557 WNSVPAIMDRVGSEIRAQGIYQENLDLRLVLLSGDWIPLHLPETVKQLFPAAKLISCGGA 1616 A+ + + ++I + + LR +L G+ + V KLI G Sbjct: 4898 MFITTALFNTL-ADINIGCLAK----LRKILFGGERASIPHVRKVLDHVGRDKLIHVYGP 4952 Query: 1617 TEASIWSIYYPIDEVMPQWTSIPYGMPLANQQFYVLNQQMDYCPLEVSGELYIGGSGVAN 1676 TE+++++ YY I+E+ + +IP G PLAN ++++ P+ V GEL I G G++ Sbjct: 4953 TESTVYATYYFINEIDDEAETIPIGSPLANTSVLIMDEAGKLLPIGVPGELCIAGDGLSK 5012 Query: 1677 GYLNDPEKPSHSFIHHPEL--GYIYRTGDYGVLHRDGCIEFLGRKDQQVKVGGYRIELGE 1734 GYLN E + FI HP + +Y+TGD DG IEF+GR D QVK+ G+RIELGE Sbjct: 5013 GYLNREELTAEKFIPHPFIPGERLYKTGDLAKWLPDGNIEFIGRIDHQVKIRGFRIELGE 5072 Query: 1735 VEAQLLRCGGVRHAVVLAADGEDKR--LGAYLIPDSQSADQAAFINEVRARIAKVLPDYM 1792 +E++L + +V + E+ R + AY+ +A++ ++E++ + + LPDYM Sbjct: 5073 IESRLEMHEDINETIVTVREDEESRPYICAYI-----TANREISLDELKGFLGEKLPDYM 5127 Query: 1793 IPHYFVVLEQFPLTANGKMDVQALLKLQPAGNKQTSA-YTAPRNDVEERIVNIFKELLEA 1851 IP YFV +++ PLT NGK+D +AL +P + T A Y APRN VE+RI++I +++L Sbjct: 5128 IPAYFVKMDKLPLTKNGKVDRKAL--PEPDRSAGTEAEYEAPRNYVEQRIISILEDVLGT 5185 Query: 1852 DQVGTLDNFFEMGINSVQIAMINNKLKQEFQKEIPLLTLFEYANIHALAGYL 1903 +++G +FF+ G NS++ + + + F ++ + T F++ +LA ++ Sbjct: 5186 ERMGISCHFFDKGGNSLKAMQAVHSINKTFGIDMRISTFFKHPTAKSLARFV 5237 >ref|ZP_00124460.1| COG1020: Non-ribosomal peptide synthetase modules and related proteins [Pseudomonas syringae pv. syringae B728a] Length = 3021 Score = 1118 bits (2892), Expect = 0.0, Method: Compositional matrix adjust. Identities = 707/2000 (35%), Positives = 1054/2000 (52%), Gaps = 121/2000 (6%) Query: 14 YWLETFSGEIPLLHLPADHSRPAFKTYRGSAEMFSIPKEQVLEIKQLAAEQEATLYMVLF 73 YW ET SG LL LP DH RPA + YRG + ++ LA +Q TL+M L Sbjct: 833 YWRETLSGAPLLLELPTDHKRPAAQDYRGGFVPLVFDRALTARLRVLATQQGTTLFMNLL 892 Query: 74 AVWNILLAKLSDQEEIIVGVPTSGRNHSDIEHVIGMFVNTLPIKSRISAKLTFAEILHAM 133 A W++LL +LS Q+++++GVP++ R+ ++E +IG FVNTL ++ S T A L Sbjct: 893 AAWSLLLMRLSGQDDVVIGVPSANRSQQELEGLIGFFVNTLALRMTRSGSPTVASWLQQA 952 Query: 134 KANISNALEHQDYPFEDLVSQLQITRDFGRNPLFDVMFXXXXXXXXXXXXXXXXXXELQM 193 ++ A EHQD PF+ +V L R +P+F V+F LQ Sbjct: 953 RSVALAAQEHQDLPFDQVVELLNPPRSLAYSPVFQVLFAWEQHQDSDLELSGLDVSVLQ- 1011 Query: 194 KPYPYTTTTSRFDLTLDGEERAGELVFTLEYATDLFTRETVMRLIRYFRTILLEVLKHPA 253 ++FDL L ER G++V LEYA+ LF ETV+++ Y R IL ++++ Sbjct: 1012 ----SVQPVAKFDLQLALSERDGQIVGGLEYASGLFEPETVVQMGEYLRRILTQMVEDSE 1067 Query: 254 QKTGLIHLPDNQETDRLLNRFNQTAGEYPEHLTVHQLFAARVKEHPHQAAVTFRNQSITY 313 Q + L + ++ R++ +N+T + + F A + P A+ +++TY Sbjct: 1068 QPLATLDLLNAEQHRRIVYDWNRTERDTSAQPDCVKRFEAVAQRTPDAVALLADERALTY 1127 Query: 314 DELNXXXXXXXXXXXXXGIGPDQIVALITTRSVDMXXXXXXXXXXXXXXXPIDPGLPANR 373 ELN G+ P+Q V L RS + P DP PA R Sbjct: 1128 AELNQSANRLANYLIEQGVRPEQCVGLCLERSPQVVIGLLAILKTGAAYVPFDPAYPAER 1187 Query: 374 IAYMLDDAGVQVILTNTSVE-------NQGNRIVLDM---RSLGLDHGAP-LPVPPVHSS 422 +A+M DA ++LT T++ + LD+ R G P +PV P Sbjct: 1188 LAFMFADAAPSLLLTQTALRAGLPPLPDTLPICCLDVQAQRWSGYSEANPQVPVSP---- 1243 Query: 423 RNLAYCMYTSGTTGLPKGILVEHRSLLNFFSAISDVLSFGKGETFLSLTTVSFDIFWLES 482 NLAY +YTSG+TG PKG+ +L N + + + L +++FD+ + E Sbjct: 1244 GNLAYVLYTSGSTGRPKGVAHSRAALDNLIA--WQLEQTPVSQRVLQFASLNFDVSFQEI 1301 Query: 483 ILPLLAGYQLVIADELQQKDVHALL-ALVKQA------EISVMQTTPSRXXXXXXXXXXX 535 L G LV+ E +KD+ AL LV + +V+Q S Sbjct: 1302 CSTLCQGGSLVLMSEAGRKDLAALRPTLVAEGVQRAFLPFAVLQQLASFTETDASVPMPL 1361 Query: 536 XXXXXXRYLLIGGEPLPQALAEQARSI---LPGGRIFNLYGPTETTIWS--------TAQ 584 ++ GE L + ++ R+ L G ++ N YGPTET + S Q Sbjct: 1362 PKGGCE--VITAGEAL--LVNDELRAFVCGLGGAQLHNQYGPTETHVVSQFSLNCDDAGQ 1417 Query: 585 EVTAGPVNIGKPLKNTQVYILNDELLLQPIGVPGILYIGGHGVVRGYQNNPELTAQRFID 644 A P IG+P+ N ++Y+L+ +L P+GV G LYI G + RGY N P+L+A+RF+ Sbjct: 1418 WPDAPP--IGRPIANARLYVLDGDLNPVPVGVAGELYIAGACLARGYLNRPDLSAERFLP 1475 Query: 645 NPYRP--GEQIYCTGDIARWTEEGTIEYLGRADFQVKIRGYRIELAEIEQQLDTHPAIEK 702 +P+ P G ++Y +GD+AR+ +G + YLGR D QVK+RG+R+EL EI+ L P + + Sbjct: 1476 DPFNPQSGARMYRSGDLARFAADGNVHYLGRIDQQVKLRGFRVELGEIDSLLHQQPGVRE 1535 Query: 703 SVVRAQRDDQDEPMLVAYYTAARTVSGAELREFLLKFLPAYMIPQHFMEIGKIPLMISGK 762 +VV + D + LVAY T LR L + LP +M+P ++ + ++PL +GK Sbjct: 1536 AVVLLREDVPGDKRLVAYVVGPATAE--TLRAELHRHLPEHMVPTAWVALAQLPLTRNGK 1593 Query: 763 LDVKALPPVTVTLVQPGETR-KPQDEVEEKLLEIWKKVLRIGDTGVQDGFFEMGGNSIQI 821 LD +ALP V Q P+DE E +++ IW +VL+ G+ D FFE+GG+S+ Sbjct: 1594 LDRQALP---VPERQAASAYVAPRDETERQMVRIWAEVLKCPQVGIHDNFFELGGHSLLA 1650 Query: 822 MQLVYEINKCFPVSFQFTHFIERQTIERIADFIKEAIQEERKEELPF--IAADPANRHEP 879 +++Y IN+ + + + +A+ ++ + + PF I AD + R+ P Sbjct: 1651 TRMIYMINQRMGGQLSLSSLFKTPVLMDLAEQVRLGRGDGPSLDTPFAPIEADRSARYAP 1710 Query: 880 FPLTNVQMAYYLGRSSHFELGGVSTHSYLEMATE-LDIRRLNQCLNTLIQRHPALHTVYL 938 FPLT++Q AY+ GR + LGGVS H Y E+ LD+ R Q LN +I RH L V+L Sbjct: 1711 FPLTDIQQAYWFGREASVSLGGVSAHGYEELRIPGLDVPRFEQALNRMILRHDMLRVVFL 1770 Query: 939 PDATQQILPEVPEYTICEYDLSGYTEEAKNKRITKERDRMSHHIFNPNVWPLFEIVAFRS 998 D TQQ+L VP Y + DL G + +A + + R+R SH + + + WPLFE Sbjct: 1771 GDGTQQVLDSVPTYHMPRNDLRGLSADAAQQALQVTRERQSHQVLDASRWPLFEFSLSLL 1830 Query: 999 SPEESLLCISFDLLIMDAYSLEILQEEIMALYADRSLQLEELSITFRDYLVGYQQMKSGK 1058 S L IS D LI+DA S +IL E+MA YAD LQL E +TFRDY++ Q++++ Sbjct: 1831 DEGISHLHISLDALIVDAASTQILARELMAFYADPQLQLPEPGLTFRDYVLAEQRLRNDS 1890 Query: 1059 WYLEDKEYWLQKVEDFPLAPGLPLLTQPQHVKNPYFKRKSKHYSQQHWRQLKQISQNHNL 1118 Y + +YW +KV AP LPL+ QP+ + P+F R+ + S W +LK++++ + Sbjct: 1891 RYAQALDYWREKVATLAPAPDLPLVCQPESISQPHFTRRDRELSALQWSRLKELARQFAV 1950 Query: 1119 TPSAVLCTVYAEVLANWSNQPQFGLNLTLFNRLPLHSDVDKLIGDFTSLLLLEVRMNPND 1178 TPS +L T ++EVLA WS QP+F L+L LFNR+PLH DVD++IGDFTSL+LLEV ++ Sbjct: 1951 TPSVMLLTAFSEVLALWSRQPRFTLSLPLFNRMPLHPDVDEIIGDFTSLVLLEVNLDGAA 2010 Query: 1179 SFWEKAGNIQRVLMEALAHRHFDGIDVMREISKRRALGNKALLPIVFTSALFDNGEDGGE 1238 SF +KA +Q L + + H G+ V+RE+S+ R + A +PIVF S L E E Sbjct: 2011 SFIDKARAVQARLWQDIDHSVVSGVRVLRELSQARGVQQTA-MPIVFNSTL---SEAAPE 2066 Query: 1239 AAE-NHGEASDGEQSTNGITQTSQVYLDNQVALIHGKMVINWDYISELFDPAVMDAMFAQ 1297 AE N +A + E + ITQT QV+LD+ + + G+++ NWD I ELF +++ MF Sbjct: 2067 LAEFNLADALNAEH-MHSITQTPQVWLDHTLLELEGRLLFNWDSIDELFPQGLIEQMFVA 2125 Query: 1298 YLSRIEAILYSREEMGFPALPASDYTSIQAYNHTEEPIP------SKTLHGLFEEAVHQT 1351 Y + ++ +L + A + ++ P+P S +H LF+ Sbjct: 2126 YNALLDRLLQAD---------AWNAGTVDLIPLARLPVPEASPADSALMHELFDRQALAA 2176 Query: 1352 PYAVAIEADNLSITYKELDDRADKVAGSLRSLGVSAGDRVGVIARKEIATFINILGILKS 1411 P A+A+ ++Y++L A ++A L+ GV V V+ + + L I + Sbjct: 2177 PDALAVIGTQRQLSYRQLRAEARQLAALLQRRGVVPNQLVAVVMERGWEQVVATLAIQYA 2236 Query: 1412 GAAYVPIDPEYPQERVDYIRNHSQCKLVLETDYYEKNCRGQHPAELQ------------- 1458 G AY+P+DP P ER+++I ++ L L + R + PA++Q Sbjct: 2237 GGAYLPLDPALPVERLEHILQRAEASLALTQPALLQ--RVEWPAQVQVISVSDSIIADAG 2294 Query: 1459 ---------RHNLPESLAYVIYTSGSTGNPKGVMISHQAACNTVQDINQKFQVGAADRML 1509 H P+ LAYVIYTSGSTG PKGV+I H+ A NT+ DIN++F VGAADR+L Sbjct: 2295 RSDQAELNAVHLTPDDLAYVIYTSGSTGMPKGVVIDHRGAVNTLLDINRRFAVGAADRVL 2354 Query: 1510 GISSLCFDLSVYDIFGAFAAGATLVLVKDQK--DIRQLADTLSAQKITIWNSVPAIMDRV 1567 +SSL FDLSVYD FG AAGA +VL++ Q+ D + ++++WNSVPA+ + Sbjct: 2355 AVSSLSFDLSVYDFFGTLAAGAAVVLLEPQQALDPAHWLTLIERHQVSLWNSVPALFGML 2414 Query: 1568 GSEIRAQGIYQENLDLRLVLLSGDWIPLHLPETVKQLFPAAKLISCGGATEASIWSIYYP 1627 ++++ LR+ +LSGDWIPL LPE L PA +L+S GGATEASIWSI YP Sbjct: 2415 LEYVQSERSVLPTC-LRVAMLSGDWIPLTLPERAWALQPALQLVSLGGATEASIWSIQYP 2473 Query: 1628 IDEVMPQWTSIPYGMPLANQQFYVLNQQMDYCPLEVSGELYIGGSGVANGYLNDPEKPSH 1687 + +V P W SIPYG L +Q+FYVL+ + P V+G+LYIGG G+A GY D + Sbjct: 2474 LQQVDPAWRSIPYGKALDHQRFYVLDDALQVRPTWVAGQLYIGGIGLAKGYWRDEALSAG 2533 Query: 1688 SFIHHPELG-YIYRTGDYGVLHRDGCIEFLGRKDQQVKVGGYRIELGEVEAQLLRCGGVR 1746 SF HP G +YRTGD G DG IEFLGR+D QVKV G+RIELGE+EA L R GV+ Sbjct: 2534 SFFAHPLTGERLYRTGDLGRWLPDGNIEFLGREDTQVKVQGHRIELGEIEAALNRHPGVQ 2593 Query: 1747 HAV--VLAADGEDKRLGAYLIPDSQSADQAAFINEVRARIAKVLPDYMIPHYFVVLEQFP 1804 AV VL +KRL Y++ S + F+ +A LP YM+P F ++++P Sbjct: 2594 SAVVRVLGEALGEKRLAGYVLKADPSLQASDFVQ----YLADKLPAYMLPTSFTFVQEWP 2649 Query: 1805 LTANGKMDVQALLKLQPAGNKQTSAYTAPRNDVEERIVNIFKELLEADQVGTLDNFFEMG 1864 L+ANGK+D + L +P+ + + E+++V I + +L+ + N +G Sbjct: 2650 LSANGKVDKKRL--PEPSQVQDAGPALEVQGPQEQQLVMIVQGVLKRPSIAADANLLNLG 2707 Query: 1865 INSVQIAMINNKLKQEFQKEIPLLTLFEYANIHALAGYLSGNDQNEP--DDVPQ-----E 1917 S+ I I+N L E Q + L + L G N N D V Q E Sbjct: 2708 ATSIDIVRISNALSGELQFRPNVAQLLAQPTLLNLLGMYRRNLVNGSVVDSVRQRAGSPE 2767 Query: 1918 QQVTRNQGKERMKQRSAKRR 1937 Q + Q + R K RR Sbjct: 2768 QVIEDPQQRARFKAEQRGRR 2787 Score = 588 bits (1515), Expect = e-166, Method: Compositional matrix adjust. Identities = 508/1762 (28%), Positives = 796/1762 (45%), Gaps = 192/1762 (10%) Query: 248 VLKHPAQKTGLIHLPDNQETDRLLNRFNQTAGEYPEHLTVHQLFAARVKEHPHQAAVTFR 307 V K ++ TG H PD ++ F+Q VH LF A+ + +P A F Sbjct: 2 VDKSSSRGTGFAH-PDTEQP------FDQNQ-------CVHGLFEAQAQRNPDAIAARFE 47 Query: 308 NQSITYDELNXXXXXXXXXXXXXGIGPDQIVALITTRSVDMXXXXXXXXXXXXXXXPIDP 367 ++ Y LN G+GPD V + RS+ M P+DP Sbjct: 48 LDTLDYATLNTQANRLAHYLRSLGVGPDVRVGICLERSLGMLVGVLAVLKAGGAYVPLDP 107 Query: 368 GLPANRIAYMLDDAGVQVILTNTSV---------ENQGNRIVLDMRSLGLDHGAPLPVPP 418 P R+A+ML D+ +V+L++ E + VLD+ L P P Sbjct: 108 AYPKARLAHMLADSAPRVLLSHAPARAALLAALEEGEVATQVLDLTDTRLWAAQPTHNPD 167 Query: 419 VH----SSRNLAYCMYTSGTTGLPKGILVEHRSLLNFFSAISDVLSFGKGETFLSLTTVS 474 H +SR+LAY +YTSG+TG+PKG++VEHR L+ +A + + L + S Sbjct: 168 PHAVGLTSRHLAYVIYTSGSTGMPKGVMVEHRGLIAVSAAWEPLYALHNPLNHLQMAGFS 227 Query: 475 FDIFWLESILPLLAGYQLVIADELQQKDVHALLALVKQAEISVMQTTPSRXXXXXXXXXX 534 FD+F + I L G LV+ D AL L+ +A I P+ Sbjct: 228 FDVFSADLIRALGFGGTLVLCPRDTLMDPPALYRLLSEARIDFADFVPAVLNPLLVWAQE 287 Query: 535 XXXXXXXRYLLIGGEPLPQALAEQARSILPG--GRIFNLYGPTETTIWSTAQEV-----T 587 ++ G + A + + L G +I YG TE +I ST E Sbjct: 288 AGRDLSFMSTVVCGSDIWTAHSARQLRGLCGEQTQIVQAYGVTEASIDSTCFEFEPDSHV 347 Query: 588 AGPVNIGKPLKNTQVYILNDELLLQPIGVPGILYIGGHGVVRGYQNNPELTAQRFIDNPY 647 + IG+ L NT++Y+L+ P GV G LYIGG GV RGY N PELT +RFID+P+ Sbjct: 348 DAVLPIGRALANTRIYLLDAAGDRVPQGVTGELYIGGAGVARGYLNLPELTRERFIDSPF 407 Query: 648 RPGEQIYCTGDIARWTEEGTIEYLGRADFQVKIRGYRIELAEIEQQLDTHPAIEKSVVRA 707 G+++Y TGD+AR+ +G +E+LGR D Q K+RG R+EL EIE +L + +VV Sbjct: 408 VAGDRLYRTGDLARYRADGHLEFLGRNDSQAKLRGLRLELGEIEARLAEVAGVRDNVVVL 467 Query: 708 QRDDQDEPMLVAYYT----AARTVSGAELREFLLKFLPAYMIPQHFMEIGKIPLMISGKL 763 + D P L+AY+ AA T G LR+ L LP YMIP F+ + +PL +GKL Sbjct: 468 REDGAGVPRLIAYFREQTGAALTPKG--LRQHLQLSLPDYMIPAAFVRMDALPLTANGKL 525 Query: 764 DVKALPPVTVTLVQPGET-------RKPQDEVEEKLLEIWKKVLRIGDTGVQDGFFEMGG 816 D ALP +PG+ Q +E L IW +VL + G QD FF +GG Sbjct: 526 DRIALP-------EPGDDAFDRHVFEAAQGALEVSLAAIWAEVLGVERVGRQDHFFALGG 578 Query: 817 NSIQIMQLVYEINKCFPVSFQFTHFIERQTIERIADFIKEAIQEERKEELPFIAADPANR 876 +S+ +M+++ ++ + + + +++ A+ + A Q + + +A R Sbjct: 579 HSLLVMRVLAKVRQTLHLEVSPSALFTAPVLQQFAERLSTARQGSPRPPIMAVA-----R 633 Query: 877 HEPFPLTNVQMAYYLGRSSHFELGGVSTHSYLEMATE--LDIRRLNQCLNTLIQRHPALH 934 E L++ Q + + E G + H L + L + L + N L+ RH A Sbjct: 634 SEAHTLSSAQQRLWF--LAQMEGGNAAYHMPLNLRLRGPLQVAALERSFNQLVTRHEAQR 691 Query: 935 TVYLP---DATQQILPEVPEYTICEYDLSGYTEEAKNKRITKERDRMSHHIFNPNVWPLF 991 T + + Q++ + DL E R+ D F+ V PL Sbjct: 692 TTFFAVEGEGRQRVAAAGAIMPLPVIDLR--DEHDAQARLLALIDAEGSKPFDLAVGPLM 749 Query: 992 EIVAFRSSPEESLLCISFDLLIMDAYSLEILQEEIMALYA---------DRSLQLEELSI 1042 + + + ++ +L ++ ++ D +S+ +L E+ LY +SL L L++ Sbjct: 750 RVSLVKLADDDHVLLLTQHHIVSDGWSMGVLTRELGLLYEAAIQQPAAHGQSLSLPPLAV 809 Query: 1043 TFRDYLVGYQQMKSGKWYLEDKEYWLQKVEDFPLAPGLPLLTQPQHVKNPYFKRKSKH-- 1100 + DY +Q G+ + YW + + PL LL P K P + Sbjct: 810 QYVDYAAWQRQWLCGEVLDAQRRYWRETLSGAPL-----LLELPTDHKRPAAQDYRGGFV 864 Query: 1101 ---YSQQHWRQLKQISQNHNLTPSAVLCTVYAEVLANWSNQPQFGLNLTLFNRLPLHSDV 1157 + + +L+ ++ T L ++ +L S Q + + NR ++ Sbjct: 865 PLVFDRALTARLRVLATQQGTTLFMNLLAAWSLLLMRLSGQDDVVIGVPSANR--SQQEL 922 Query: 1158 DKLIGDFTSLLLLEVRMNPNDSFWEKAGNIQRVLMEALAHRHFDGIDVMREISKRRALGN 1217 + LIG F + L L + + + + + V + A H+ V+ ++ R+L Sbjct: 923 EGLIGFFVNTLALRMTRSGSPTVASWLQQARSVALAAQEHQDLPFDQVVELLNPPRSLAY 982 Query: 1218 KALLPIVFTSALFDNGEDGGEAAENHGEASDGEQSTNGITQTSQV----YLDNQVALIH- 1272 + ++F A E H + SD E S ++ V D Q+AL Sbjct: 983 SPVFQVLF-------------AWEQH-QDSDLELSGLDVSVLQSVQPVAKFDLQLALSER 1028 Query: 1273 -GKMVINWDYISELFDPAVMDAMFAQYLSRIEAILYSREEMGFPALPASDYTS----IQA 1327 G++V +Y S LF+P + M +YL RI + E L + + Sbjct: 1029 DGQIVGGLEYASGLFEPETVVQM-GEYLRRILTQMVEDSEQPLATLDLLNAEQHRRIVYD 1087 Query: 1328 YNHTEEPIPSK-TLHGLFEEAVHQTPYAVAIEADNLSITYKELDDRADKVAGSLRSLGVS 1386 +N TE ++ FE +TP AVA+ AD ++TY EL+ A+++A L GV Sbjct: 1088 WNRTERDTSAQPDCVKRFEAVAQRTPDAVALLADERALTYAELNQSANRLANYLIEQGVR 1147 Query: 1387 AGDRVGVIARKEIATFINILGILKSGAAYVPIDPEYPQERVDYIRNHSQCKLVLET---- 1442 VG+ + I +L ILK+GAAYVP DP YP ER+ ++ + L+L Sbjct: 1148 PEQCVGLCLERSPQVVIGLLAILKTGAAYVPFDPAYPAERLAFMFADAAPSLLLTQTALR 1207 Query: 1443 ---------------DYYEKNCRGQHPAELQRHNLPESLAYVIYTSGSTGNPKGVMISHQ 1487 D + G A Q P +LAYV+YTSGSTG PKGV S Sbjct: 1208 AGLPPLPDTLPICCLDVQAQRWSGYSEANPQVPVSPGNLAYVLYTSGSTGRPKGVAHSRA 1267 Query: 1488 AACNTVQDINQKFQVGAADRMLGISSLCFDLSVYDIFGAFAAGATLVLVKD--QKDIRQL 1545 A N + Q Q + R+L +SL FD+S +I G +LVL+ + +KD+ L Sbjct: 1268 ALDNLI--AWQLEQTPVSQRVLQFASLNFDVSFQEICSTLCQGGSLVLMSEAGRKDLAAL 1325 Query: 1546 ADTLSAQKITIWNSVPAIMDRVGSEIRAQGIYQENLDLRLVLLSGDWIPLHLPETVKQLF 1605 TL A+ + A++ ++ S +P+ LP+ ++ Sbjct: 1326 RPTLVAEGVQRAFLPFAVLQQLASFTETDAS----------------VPMPLPKGGCEVI 1369 Query: 1606 PAA---------KLISCG----------GATEASIWSIYYPIDEVMPQWTSI-PYGMPLA 1645 A + CG G TE + S + + QW P G P+A Sbjct: 1370 TAGEALLVNDELRAFVCGLGGAQLHNQYGPTETHVVSQFSLNCDDAGQWPDAPPIGRPIA 1429 Query: 1646 NQQFYVLNQQMDYCPLEVSGELYIGGSGVANGYLNDPEKPSHSFI---HHPELG-YIYRT 1701 N + YVL+ ++ P+ V+GELYI G+ +A GYLN P+ + F+ +P+ G +YR+ Sbjct: 1430 NARLYVLDGDLNPVPVGVAGELYIAGACLARGYLNRPDLSAERFLPDPFNPQSGARMYRS 1489 Query: 1702 GDYGVLHRDGCIEFLGRKDQQVKVGGYRIELGEVEAQLLRCGGVRHAVVLAADG--EDKR 1759 GD DG + +LGR DQQVK+ G+R+ELGE+++ L + GVR AVVL + DKR Sbjct: 1490 GDLARFAADGNVHYLGRIDQQVKLRGFRVELGEIDSLLHQQPGVREAVVLLREDVPGDKR 1549 Query: 1760 LGAYLIPDSQSADQAAFINEVRARIAKVLPDYMIPHYFVVLEQFPLTANGKMDVQALLKL 1819 L AY++ A +RA + + LP++M+P +V L Q PLT NGK+D QAL Sbjct: 1550 LVAYVV-------GPATAETLRAELHRHLPEHMVPTAWVALAQLPLTRNGKLDRQAL--- 1599 Query: 1820 QPAGNKQ-TSAYTAPRNDVEERIVNIFKELLEADQVGTLDNFFEMGINSVQIAMINNKLK 1878 P +Q SAY APR++ E ++V I+ E+L+ QVG DNFFE+G +S+ + + Sbjct: 1600 -PVPERQAASAYVAPRDETERQMVRIWAEVLKCPQVGIHDNFFELGGHSLLATRMIYMIN 1658 Query: 1879 QEFQKEIPLLTLFEYANIHALA 1900 Q ++ L +LF+ + LA Sbjct: 1659 QRMGGQLSLSSLFKTPVLMDLA 1680 Score = 275 bits (702), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 202/623 (32%), Positives = 299/623 (47%), Gaps = 49/623 (7%) Query: 1327 AYNHTEEPIP-SKTLHGLFEEAVHQTPYAVAIEADNLSITYKELDDRADKVAGSLRSLGV 1385 A+ TE+P ++ +HGLFE + P A+A + ++ Y L+ +A+++A LRSLGV Sbjct: 13 AHPDTEQPFDQNQCVHGLFEAQAQRNPDAIAARFELDTLDYATLNTQANRLAHYLRSLGV 72 Query: 1386 SAGDRVGVIARKEIATFINILGILKSGAAYVPIDPEYPQERVDYIRNHSQCKLVLE---- 1441 RVG+ + + + +L +LK+G AYVP+DP YP+ R+ ++ S +++L Sbjct: 73 GPDVRVGICLERSLGMLVGVLAVLKAGGAYVPLDPAYPKARLAHMLADSAPRVLLSHAPA 132 Query: 1442 -----------------TDYYEKNCRGQHPAELQRHN--------LPESLAYVIYTSGST 1476 D + P HN LAYVIYTSGST Sbjct: 133 RAALLAALEEGEVATQVLDLTDTRLWAAQPT----HNPDPHAVGLTSRHLAYVIYTSGST 188 Query: 1477 GNPKGVMISHQAACNTVQDINQKFQVGAADRMLGISSLCFDLSVYDIFGAFAAGATLVLV 1536 G PKGVM+ H+ + + L ++ FD+ D+ A G TLVL Sbjct: 189 GMPKGVMVEHRGLIAVSAAWEPLYALHNPLNHLQMAGFSFDVFSADLIRALGFGGTLVLC 248 Query: 1537 KDQK--DIRQLADTLSAQKITIWNSVPAIMDRVGSEIRAQGIYQENLDLRLVLLSGDWIP 1594 D L LS +I + VPA+++ + + AQ ++ + V+ D Sbjct: 249 PRDTLMDPPALYRLLSEARIDFADFVPAVLNPL--LVWAQEAGRDLSFMSTVVCGSDIWT 306 Query: 1595 LHLPETVKQLF-PAAKLISCGGATEASIWSIYYPIDEVMPQWTSIPYGMPLANQQFYVLN 1653 H ++ L +++ G TEASI S + + +P G LAN + Y+L+ Sbjct: 307 AHSARQLRGLCGEQTQIVQAYGVTEASIDSTCFEFEPDSHVDAVLPIGRALANTRIYLLD 366 Query: 1654 QQMDYCPLEVSGELYIGGSGVANGYLNDPEKPSHSFIHHPELG--YIYRTGDYGVLHRDG 1711 D P V+GELYIGG+GVA GYLN PE FI P + +YRTGD DG Sbjct: 367 AAGDRVPQGVTGELYIGGAGVARGYLNLPELTRERFIDSPFVAGDRLYRTGDLARYRADG 426 Query: 1712 CIEFLGRKDQQVKVGGYRIELGEVEAQLLRCGGVR-HAVVLAADGED-KRLGAYLIPDSQ 1769 +EFLGR D Q K+ G R+ELGE+EA+L GVR + VVL DG RL AY + Sbjct: 427 HLEFLGRNDSQAKLRGLRLELGEIEARLAEVAGVRDNVVVLREDGAGVPRLIAYF---RE 483 Query: 1770 SADQAAFINEVRARIAKVLPDYMIPHYFVVLEQFPLTANGKMDVQALLKLQPAGNK-QTS 1828 A +R + LPDYMIP FV ++ PLTANGK+D AL +P + Sbjct: 484 QTGAALTPKGLRQHLQLSLPDYMIPAAFVRMDALPLTANGKLDRIAL--PEPGDDAFDRH 541 Query: 1829 AYTAPRNDVEERIVNIFKELLEADQVGTLDNFFEMGINSVQIAMINNKLKQEFQKEIPLL 1888 + A + +E + I+ E+L ++VG D+FF +G +S+ + + K++Q E+ Sbjct: 542 VFEAAQGALEVSLAAIWAEVLGVERVGRQDHFFALGGHSLLVMRVLAKVRQTLHLEVSPS 601 Query: 1889 TLFEYANIHALAGYLSGNDQNEP 1911 LF + A LS Q P Sbjct: 602 ALFTAPVLQQFAERLSTARQGSP 624 >ref|ZP_00179483.1| hypothetical protein Cwat036301 [Crocosphaera watsonii WH 8501] Length = 2449 Score = 1104 bits (2855), Expect = 0.0, Method: Compositional matrix adjust. Identities = 658/1804 (36%), Positives = 978/1804 (54%), Gaps = 70/1804 (3%) Query: 14 YWLETFSGEIPLLHLPADHSRPAFKTYRGSAEMFSIPKEQVLEIKQLAAEQEATLYMVLF 73 YW E ++P+L LP SRP +YRG ++ +K ++A+++ TL+ +L Sbjct: 246 YWQEKLGQDLPILDLPTKRSRPLVPSYRGKHHPIALSPALSDSLKAVSAKEKVTLFTLLL 305 Query: 74 AVWNILLAKLSDQEEIIVGVPTSGRNHSDIEHVIGMFVNTLPIKSRISAKLTFAEILHAM 133 + + +LL + +DQ++I++G + RN ++E +IG+ VNTL +++ +S +F +L + Sbjct: 306 SAFKVLLCRYTDQDDIVIGTEIANRNRREMEGLIGLLVNTLVLRTDLSGNPSFKTVLQRV 365 Query: 134 KANISNALEHQDYPFEDLVSQLQITRDFGRN-PLFDVMFXXXXXXXXXXXXXXXXXXELQ 192 + A HQD PFE LV L R + PLF V F +L Sbjct: 366 REVTLGAYAHQDLPFEKLVEVLNPDRHLSQMMPLFQVKFDFQLATVKPLQLS-----DLS 420 Query: 193 MKPYPYTTTTSRFDLTLDGEERAGELVFTLEYATDLFTRETVMRLIRYFRTILLEVLKHP 252 ++ T +++L L+ ++ + +EY+TDLFT ET+ R+ +F+ +L ++ +P Sbjct: 421 LERLLGEQETVKYELRLNLQDTNEGINGQIEYSTDLFTDETIARMAEHFQVLLEGIISNP 480 Query: 253 AQKTGLIHLPDNQETDRLL--NRFNQTAGEYPEHLTVHQLFAARVKEHPHQAAVTFRNQS 310 + + L E +LL N ++ P + + QLF +V ++P A++F + Sbjct: 481 EKPISELPLLSQIEQAKLLTVNSEQFSSLSIPNNANIPQLFEEQVNKNPDAIALSFGEEK 540 Query: 311 ITYDELNXXXXXXXXXXXXXGIGPDQIVALITTRSVDMXXXXXXXXXXXXXXXPIDPGLP 370 +TY E+N G+ P+ V + RS M P+DP P Sbjct: 541 LTYQEINIQANKLAHYLQKLGVKPEVKVGICFERSPLMVIGLLAILKAGGAYIPLDPAYP 600 Query: 371 ANRIAYMLDDAGVQVILTNTSVE-NQGN--RIVLDMRSLGLDHGAPLPVPPVHSSRNLAY 427 R+ ++L+DA + ++L+ S E +G+ I LD NLAY Sbjct: 601 QERLNFILEDAQISILLSRQSQEIKKGDFATIDLDKDCAKFAQEKTENPDNNLDPNNLAY 660 Query: 428 CMYTSGTTGLPKGILVEHRSLLNFFSAISDVLSFGKGETFLSLTTVSFDIFWLESILPLL 487 +YTSG+TG PKG+ + HR+ + + S + L+ T++ FD+ E +PL Sbjct: 661 VIYTSGSTGNPKGVAIAHRNTVELLYWAKNSFSPQLLQGVLASTSICFDLSVFELFVPLC 720 Query: 488 AGYQLVIADELQQKDVHALLALVKQAEISVMQTTPSRXXXXXXXXXXXXXXXXXRYLLIG 547 GYQ+++++ +V L L + EI+++ T PS + + + Sbjct: 721 WGYQVILSE-----NVLDLPYLAAKEEITLINTVPS---AIAQLLRINGIPTSVKAINLA 772 Query: 548 GEPLPQALAEQARSILPGGRIFNLYGPTETTIWSTAQEVTA---GPVNIGKPLKNTQVYI 604 GE LP L E+ + IFNLYGP+E T +ST V + G V IGK + NTQ YI Sbjct: 773 GEALPHRLVEELEKLSHIETIFNLYGPSEDTTYSTYTSVKSNADGVVTIGKGISNTQTYI 832 Query: 605 LNDELLLQPIGVPGILYIGGHGVVRGYQNNPELTAQRFIDNPYRPG--EQIYCTGDIARW 662 L+ L L P GV G LY+ G G+ RGY LTA++F+ NP+ G ++Y TGD+ R+ Sbjct: 833 LDRYLNLVPQGVIGELYLSGAGITRGYLGRSPLTAEKFLPNPFMEGIYSRLYKTGDLVRY 892 Query: 663 TEEGTIEYLGRADFQVKIRGYRIELAEIEQQLDTHPAIEKSVVRAQRDDQDEPMLVAYYT 722 EG +E+LGR D QVK+RGYR+E+ EIE L +P I ++ V R+D + L AY Sbjct: 893 DGEGNLEFLGRRDNQVKVRGYRLEIGEIEAALSQYPDIIENAVMVWREDNNNQRLTAYIV 952 Query: 723 AARTVSGAELREFLLKFLPAYMIPQHFMEIGKIPLMISGKLDVKALP-PVTVTLVQPGET 781 S +LR FL + LP Y IP F+E+ +P + +GKLD K+LP P + E Sbjct: 953 VEEAFSQKQLRRFLGEKLPKYAIPTTFLELPALPRLPNGKLDRKSLPLPENLGRSLENEY 1012 Query: 782 RKPQDEVEEKLLEIWKKVLRIGDTGVQDGFFEMGGNSIQIMQLVYEINKCFPVSFQFTHF 841 +PQ E E+ + EIW+ L+I G+ D FFE+GG+S+ + ++ E+++ + Sbjct: 1013 IEPQIETEKIIAEIWQNALKIEKIGLYDNFFELGGHSLLAINVIAEMSEKLEIKISLRSL 1072 Query: 842 IERQTIERI-ADFIKEAIQEERKEELPFIAADPANRHEPFPLTNVQMAYYLGRSSHFELG 900 ++ TI + A + E LP + + R++PFPLT++Q AY +GRS+ FELG Sbjct: 1073 FQQPTIAGLEAQISGNELIESVTANLPTLVVNTEQRYQPFPLTDIQQAYLIGRSAAFELG 1132 Query: 901 GVSTHSYLEMAT-ELDIRRLNQCLNTLIQRHPALHTVYLPDATQQILPEVPEYTICEYDL 959 V+TH Y E+ T L+++++ + N LIQRH L V D Q+ILP+VP Y + DL Sbjct: 1133 NVATHGYREIETVGLNVQKVEEAFNILIQRHDMLRMVVDEDGKQRILPDVPRYDLKTLDL 1192 Query: 960 SGYTEEAKNKRITKERDRMSHHIFNPNVWPLFEIVAFRSSPEESLLCISFDLLIMDAYSL 1019 E R+ RDR+SH IF + +PLFEI A ++ +SF++L+ DA+S Sbjct: 1193 QQEDETTIASRLETLRDRLSHQIFTTDQYPLFEIQAILLPEDKIRFMVSFEVLLGDAWSF 1252 Query: 1020 EILQEEIMALYADRSLQLEELSITFRDYLVGYQQMKSGKWYLEDKEYWLQKVEDFPLAPG 1079 ++L E + +++ L L+I+FRDY++ + + Y YW ++ P +P Sbjct: 1253 QLLGYEFAQILENKANLLPPLTISFRDYVMAENSWRDSEDYQHSLTYWQNRLSSLPPSPE 1312 Query: 1080 LPLLTQPQHVKNPYFKRKSKHYSQQHWRQLKQISQNHNLTPSAVLCTVYAEVLANWSNQP 1139 LPL + V P+F R+S W++LK + +TPS +L +AE+L WS Sbjct: 1313 LPLTKRLGAVTQPHFVRRSGKLKANDWQKLKDQASRLGITPSGLLLAAFAEILTTWSKNH 1372 Query: 1140 QFGLNLTLFNRLPLHSDVDKLIGDFTSLLLLEVRMNPNDSFWEKAGNIQRVLMEALAHRH 1199 +F LNLTLFNRLP+H ++++LIGDFTS LLL V DSF KA IQ L E L HRH Sbjct: 1373 EFTLNLTLFNRLPIHPEINRLIGDFTSSLLLAVNNKGQDSFSTKARRIQGQLWEDLDHRH 1432 Query: 1200 FDGIDVMREISKRRALGNKALLPIVFTSALFDNGEDGGEAAENHGEASDGEQSTNGITQT 1259 G+ ++RE+S+ R +AL+P+VFTS L + + + ++QT Sbjct: 1433 VSGVKILRELSRLRGGKGEALMPVVFTSTLTQTSQQTSSSRSWDADV------VYSVSQT 1486 Query: 1260 SQVYLDNQVALIHGKMVINWDYISELFDPAVMDAMFAQY---LSRIEAILYSREEMGFPA 1316 SQVYLD+QV+ I G+++ NWD I ELF ++D MF Y L R+ A E Sbjct: 1487 SQVYLDHQVSEIAGELIFNWDAIEELFPTGLLDDMFTAYSSFLERLAADTTLWESQTLDL 1546 Query: 1317 LPASDYTSIQAYNHTEEPIPSKT--LHGLFEEAVHQTPYAVAIEADNLSITYKELDDRAD 1374 LP I N+TE+ + LH LF E V + P +AI +++TY+EL DR Sbjct: 1547 LPPEQIKIITEINNTEKTFKQENSLLHELFFEQVRENPQKIAIIDPRITLTYQELSDRIL 1606 Query: 1375 KVAGSLRSLGVSAGDRVGVIARKEIATFINILGILKSGAAYVPIDPEYPQERVDYIRNHS 1434 +A LR+LG+ V V+ K I +LGIL +G AYVPID P E Y+ Sbjct: 1607 TLAHRLRNLGIKPNQLVAVMMEKGWEQIIAVLGILTAGGAYVPIDTALPLESSYYLLKEI 1666 Query: 1435 QCKLVLETDYYEKNCRGQHPAELQRHNL-----------------PESLAYVIYTSGSTG 1477 + +L + + + P LQR ++ P+ LAY+IYTSGSTG Sbjct: 1667 KANQILTQSWLDI----ETPDNLQRIDIDTLETSNTFEPLKSVQKPDDLAYIIYTSGSTG 1722 Query: 1478 NPKGVMISHQAACNTVQDINQKFQVGAADRMLGISSLCFDLSVYDIFGAFAAGATLVLVK 1537 PKGV I+HQ A NT+ DINQ+F V D+++ +S+L FDLSVYDIFG A GATLV+ + Sbjct: 1723 MPKGVAIAHQGAVNTILDINQRFAVSGKDKVIALSALNFDLSVYDIFGTLAVGATLVIPE 1782 Query: 1538 D--QKDIRQLADTLSAQKITIWNSVPAIMDRVGSEIRAQGIYQENLDLRLVLLSGDWIPL 1595 ++D AD LS ITIWNSVPA+M + E A + +LRLVLLSGDW+PL Sbjct: 1783 HDRRQDPSHWADLLSQHHITIWNSVPALMQML-LETEAS-----DENLRLVLLSGDWLPL 1836 Query: 1596 HLPETVKQLFPAAKLISCGGATEASIWSIYYPIDEVMPQWTSIPYGMPLANQQFYVLNQQ 1655 +L + + FP ++IS GGATEASIWSI+YPID V P W SIPYG PL NQQFYVL + Sbjct: 1837 NLSDRIHSRFPITEVISLGGATEASIWSIFYPIDRVDPSWKSIPYGKPLTNQQFYVLGEY 1896 Query: 1656 MDYCPLEVSGELYIGGSGVANGYLNDPEKPSHSFIHHPELG-YIYRTGDYGVLHRDGCIE 1714 + CPL V+G+LYIGG G+A Y + EK SFI +P +Y+TGD G DG IE Sbjct: 1897 LTPCPLWVTGQLYIGGKGLAEFYWQNTEKTEVSFIINPHTKERLYKTGDLGRYLPDGNIE 1956 Query: 1715 FLGRKDQQVKVGGYRIELGEVEAQLLRCGGVRHAVV--LAADGEDKRLGAYLIPDSQSAD 1772 FLGR+D QVK+ GYRIELGE+E L + ++ AVV + E+++L AY++P S Sbjct: 1957 FLGREDYQVKIRGYRIELGEIETALEQHPAIKEAVVTIVGESRENEQLAAYIVPLQSSGV 2016 Query: 1773 QAAF 1776 A+ Sbjct: 2017 PDAY 2020 Score = 324 bits (830), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 285/1087 (26%), Positives = 514/1087 (47%), Gaps = 102/1087 (9%) Query: 880 FPLTNVQMAYYLGRSSHFELGGVSTHSYLEMATELDIRRLNQCLNTLIQRHPALHTVYLP 939 PL+ Q + + + + S + +L + L Q LN +++RH L T + Sbjct: 46 IPLSFAQQRLWFIQQLEPDNNSYNVPSSFRIKGKLQVEILEQTLNEIVKRHEMLRTSFTT 105 Query: 940 DATQQ----ILPEVPEYTICEYDLSGYTE-EAKNKRITKERDRMSHHIFNPNVWPLFEIV 994 D+ +Q + P P +++ DL EA+ +R+ R+ + + ++ ++ Sbjct: 106 DSDRQPIQVVTPFQP-FSLPIIDLQDIANAEAEVQRLVI-REFLRPFDLSESL---LRLI 160 Query: 995 AFRSSPEESLLCISFDLLIMDAYSLEILQEEIMALYA--------------DRSLQLEEL 1040 + S +E +L I+ ++ D +S+ + E+ LY L L L Sbjct: 161 LLKLSEKEHILLITTHHIVCDRWSIGVFLREMTTLYNGFFKATEVGKGEDNKTPLNLSPL 220 Query: 1041 SITFRDYLVGYQQMKSGKWYLEDKEYWLQKVEDFPLAPGLPLLTQPQHVKNPYFKR-KSK 1099 I + D+ + +Q G + YW +K L LP+L P P + K Sbjct: 221 PIQYGDWSIWQRQWLQGDLLDKQINYWQEK-----LGQDLPILDLPTKRSRPLVPSYRGK 275 Query: 1100 HY----SQQHWRQLKQISQNHNLTPSAVLCTVYAEVLANWSNQPQFGLNLTLFNRLPLHS 1155 H+ S LK +S +T +L + + +L +++Q + + NR Sbjct: 276 HHPIALSPALSDSLKAVSAKEKVTLFTLLLSAFKVLLCRYTDQDDIVIGTEIANRN--RR 333 Query: 1156 DVDKLIGDFTSLLLLEVRMNPNDSFWEKAGNIQRVLMEALAHRHFDGIDVMREISKRRAL 1215 +++ LIG + L+L ++ N SF ++ V + A AH+ ++ ++ R L Sbjct: 334 EMEGLIGLLVNTLVLRTDLSGNPSFKTVLQRVREVTLGAYAHQDLPFEKLVEVLNPDRHL 393 Query: 1216 GNKALLPIVFTSALFDNGEDGGEAAENHGEASD-------GEQSTNGITQTSQVYLDNQV 1268 ++P LF D A + SD GEQ T + ++ L + Sbjct: 394 SQ--MMP------LFQVKFDFQLATVKPLQLSDLSLERLLGEQET--VKYELRLNLQDTN 443 Query: 1269 ALIHGKMVINWDYISELFDPAVMDAMFAQYLSRIEAILYSREEMGFPALP------ASDY 1322 I+G++ +Y ++LF + M + +E I+ S E LP + Sbjct: 444 EGINGQI----EYSTDLFTDETIARMAEHFQVLLEGII-SNPEKPISELPLLSQIEQAKL 498 Query: 1323 TSIQAYNHTEEPIPSK-TLHGLFEEAVHQTPYAVAIEADNLSITYKELDDRADKVAGSLR 1381 ++ + + IP+ + LFEE V++ P A+A+ +TY+E++ +A+K+A L+ Sbjct: 499 LTVNSEQFSSLSIPNNANIPQLFEEQVNKNPDAIALSFGEEKLTYQEINIQANKLAHYLQ 558 Query: 1382 SLGVSAGDRVGVIARKEIATFINILGILKSGAAYVPIDPEYPQERVDYIRNHSQCKLVLE 1441 LGV +VG+ + I +L ILK+G AY+P+DP YPQER+++I +Q ++L Sbjct: 559 KLGVKPEVKVGICFERSPLMVIGLLAILKAGGAYIPLDPAYPQERLNFILEDAQISILLS 618 Query: 1442 TDYYE------------KNCR--GQHPAELQRHNLPESL-AYVIYTSGSTGNPKGVMISH 1486 E K+C Q E +NL + AYVIYTSGSTGNPKGV I+H Sbjct: 619 RQSQEIKKGDFATIDLDKDCAKFAQEKTENPDNNLDPNNLAYVIYTSGSTGNPKGVAIAH 678 Query: 1487 QAACNTVQDINQKFQVGAADRMLGISSLCFDLSVYDIFGAFAAGATLVLVKDQKDIRQLA 1546 + + F +L +S+CFDLSV+++F G ++L ++ D+ LA Sbjct: 679 RNTVELLYWAKNSFSPQLLQGVLASTSICFDLSVFELFVPLCWGYQVILSENVLDLPYLA 738 Query: 1547 DTLSAQKITIWNSVPAIMDRVGSEIRAQGIYQENLDLRLVLLSGDWIPLHLPETVKQLFP 1606 + ++IT+ N+VP+ + ++ +R GI ++ + L+G+ +P L E +++L Sbjct: 739 ---AKEEITLINTVPSAIAQL---LRINGI---PTSVKAINLAGEALPHRLVEELEKLSH 789 Query: 1607 AAKLISCGGATEASIWSIYYPIDEVMPQWTSIPYGMPLANQQFYVLNQQMDYCPLEVSGE 1666 + + G +E + +S Y + +I G ++N Q Y+L++ ++ P V GE Sbjct: 790 IETIFNLYGPSEDTTYSTYTSVKSNADGVVTI--GKGISNTQTYILDRYLNLVPQGVIGE 847 Query: 1667 LYIGGSGVANGYLNDPEKPSHSFIHHPEL----GYIYRTGDYGVLHRDGCIEFLGRKDQQ 1722 LY+ G+G+ GYL + F+ +P + +Y+TGD +G +EFLGR+D Q Sbjct: 848 LYLSGAGITRGYLGRSPLTAEKFLPNPFMEGIYSRLYKTGDLVRYDGEGNLEFLGRRDNQ 907 Query: 1723 VKVGGYRIELGEVEAQLLRCGGVRHAVVLA--ADGEDKRLGAYLIPDSQSADQAAFINEV 1780 VKV GYR+E+GE+EA L + + V+ D ++RL AY++ ++A ++ Sbjct: 908 VKVRGYRLEIGEIEAALSQYPDIIENAVMVWREDNNNQRLTAYIV-----VEEAFSQKQL 962 Query: 1781 RARIAKVLPDYMIPHYFVVLEQFPLTANGKMDVQALLKLQPAGNKQTSAYTAPRNDVEER 1840 R + + LP Y IP F+ L P NGK+D ++L + G + Y P+ + E+ Sbjct: 963 RRFLGEKLPKYAIPTTFLELPALPRLPNGKLDRKSLPLPENLGRSLENEYIEPQIETEKI 1022 Query: 1841 IVNIFKELLEADQVGTLDNFFEMGINSVQIAMINNKLKQEFQKEIPLLTLFEYANIHALA 1900 I I++ L+ +++G DNFFE+G +S+ + ++ ++ + +I L +LF+ I L Sbjct: 1023 IAEIWQNALKIEKIGLYDNFFELGGHSLLAINVIAEMSEKLEIKISLRSLFQQPTIAGLE 1082 Query: 1901 GYLSGND 1907 +SGN+ Sbjct: 1083 AQISGNE 1089 Score = 95.5 bits (236), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 44/112 (39%), Positives = 72/112 (64%) Query: 1788 LPDYMIPHYFVVLEQFPLTANGKMDVQALLKLQPAGNKQTSAYTAPRNDVEERIVNIFKE 1847 +P+YMIP + +L+Q PL ANGK+D +L K + + AP+ +++E++ I+K+ Sbjct: 2280 IPNYMIPRSYTILKQLPLNANGKIDRNSLPKPNILAATSSIEFVAPQTEIQEQLATIWKQ 2339 Query: 1848 LLEADQVGTLDNFFEMGINSVQIAMINNKLKQEFQKEIPLLTLFEYANIHAL 1899 LE ++VG DNFF++G NS+ + + +K++Q FQ E+PL LFE I L Sbjct: 2340 YLEIEKVGIYDNFFDLGGNSLLVTQVISKVRQTFQVELPLQKLFETPTIAEL 2391 Score = 81.6 bits (200), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 41/123 (33%), Positives = 68/123 (55%), Gaps = 1/123 (0%) Query: 735 FLLKFLPAYMIPQHFMEIGKIPLMISGKLDVKALP-PVTVTLVQPGETRKPQDEVEEKLL 793 +L +P YMIP+ + + ++PL +GK+D +LP P + E PQ E++E+L Sbjct: 2275 YLQDKIPNYMIPRSYTILKQLPLNANGKIDRNSLPKPNILAATSSIEFVAPQTEIQEQLA 2334 Query: 794 EIWKKVLRIGDTGVQDGFFEMGGNSIQIMQLVYEINKCFPVSFQFTHFIERQTIERIADF 853 IWK+ L I G+ D FF++GGNS+ + Q++ ++ + F V E TI + Sbjct: 2335 TIWKQYLEIEKVGIYDNFFDLGGNSLLVTQVISKVRQTFQVELPLQKLFETPTIAELELL 2394 Query: 854 IKE 856 I+E Sbjct: 2395 IQE 2397 >ref|NP_356935.1| AGR_L_2311p [Agrobacterium tumefaciens] ref|NP_534178.1| non-ribosomal peptide synthetase [Agrobacterium tumefaciens str. C58 (U. Washington)] pir||F98274 hypothetical protein AGR_L_2311 [imported] - Agrobacterium tumefaciens (strain C58, Cereon) pir||AH3009 non-ribosomal peptide synthetase mtaD [imported] - Agrobacterium tumefaciens (strain C58, Dupont) gb|AAK89720.1| AGR_L_2311p [Agrobacterium tumefaciens str. C58 (Cereon)] gb|AAL44494.1| non-ribosomal peptide synthetase [Agrobacterium tumefaciens str. C58 (U. Washington)] Length = 2399 Score = 1036 bits (2680), Expect = 0.0, Method: Compositional matrix adjust. Identities = 627/1797 (34%), Positives = 955/1797 (53%), Gaps = 77/1797 (4%) Query: 14 YWLETFSGEIPLLHLPADHSRPAFKTYRGSAEMFSIPKEQVLEIKQLAAEQEATLYMVLF 73 YW + ++P+L LP D RPA ++ G+ S+ E++ LA +LY++L Sbjct: 235 YWKKALGTDLPVLDLPFDRPRPAIASFLGAQFAVSVDPALSGELRALARAHNVSLYVLLL 294 Query: 74 AVWNILLAKLSDQEEIIVGVPTSGRNHSDIEHVIGMFVNTLPIKSRISAKLTFAEILHAM 133 + + ++L D ++I+VG + R+ + + +IG VNTL +++ ++ F+ +L + Sbjct: 295 SAFKLVLHLYCDSDDIVVGSEVANRDRPETQAMIGPLVNTLVLRTDLAGNPDFSGLLQRV 354 Query: 134 KANISNALEHQDYPFEDLVSQLQITRDFGR-NPLFDVMFXXXXXXXXXXXXXXXXXXELQ 192 + L +QD P+E +V L R PLF F L+ Sbjct: 355 SETVRTGLANQDVPYERIVEALNPKRSLSEMTPLFQAKFDLQHNLARLPELDGLAIETLR 414 Query: 193 MKPYPYTTTTSRFDLTLDGEERAGELVFTLEYATDLFTRETVMRLIRYFRTILLEVLKHP 252 + P RF+L + + G++ EYATDLF ETV + R F +L + + P Sbjct: 415 L-PDGAAKNEIRFNLEDNDPDIGGKI----EYATDLFNEETVATIWRRFEDVLRTIAEDP 469 Query: 253 AQKTGLIHLPDNQETDRLLNRFNQTAGE--YPEHLTVHQLFAARVKEHPHQAAVTFRNQS 310 A++ L + E + R +AG+ L +H++ A+ P ++AV + Sbjct: 470 ARRLSEFSLLCDDEQQEQIRR---SAGQALTQSGLCLHEMLTAQATRTPEKSAVASEHGK 526 Query: 311 ITYDELNXXXXXXXXXXXXXGIGPDQIVALITTRSVDMXXXXXXXXXXXXXXXPIDPGLP 370 +TY EL+ G G IV + R+ D+ P+DP P Sbjct: 527 LTYRELDQRSDAIAAALAASGFGRGSIVGVCMQRTPDLIAALFGVLKAGAAYVPLDPDYP 586 Query: 371 ANRIAYMLDDAGVQVILTNTSVENQGNRIVLDMRSLGLDHGAPLPVPPVHSSRNLAYCMY 430 + R+A++ DA ++V+LT++ + L + +G A +LAY +Y Sbjct: 587 SERLAFIAQDAAIRVVLTDSDRLAFDATVDLMLLEVGKLPDAVFSAAHACDPADLAYIIY 646 Query: 431 TSGTTGLPKGILVEHRSLLNFFSAISDVLSFGKGETFLSLTTVSFDIFWLESILPLLAGY 490 TSG+TG PKG+ + H + ++ + + + L+ T+V FD+ E L G Sbjct: 647 TSGSTGRPKGVAITHGNAAARMQWTANNFTSDELASVLASTSVCFDLSIFEIFGTLSCGG 706 Query: 491 QLVIADELQQKDVHALLALVKQAEISVMQTTPSRXXXXXXXXXXXXXXXXXRYLLIGGEP 550 Q+V+A+ L L L E+S++ T PS + GEP Sbjct: 707 QVVLANTL-----FDLPRLQHVVEVSLINTVPSLLREYLRHDALPTSVSAVN---LAGEP 758 Query: 551 LPQALAEQARSILPGGRIFNLYGPTETTIWSTAQEVTA----GPVNIGKPLKNTQVYILN 606 LP L E+ P RI NLYGP+E T +ST V A V+IG PL TQ Y+L+ Sbjct: 759 LPPVLLEELAKKAPQARIHNLYGPSEDTTYSTGAMVRAVSGEKTVSIGAPLPGTQAYVLD 818 Query: 607 DELLLQPIGVPGILYIGGHGVVRGYQNNPELTAQRFIDNPY--RPGEQIYCTGDIARWTE 664 L+P G+ G LY+GG GV RGY P TA+RF+ + + R +Y TGD R Sbjct: 819 RAGRLRPDGLAGELYLGGAGVTRGYLRRPSQTAERFVPDAFSGRSSSYLYRTGDRVRRRA 878 Query: 665 EGTIEYLGRADFQVKIRGYRIELAEIEQQLDTHPAIEKSVVRAQRDDQD-EPMLVAYYT- 722 +G +E+ GR D QVKIRG RIE+ EIE QL+ + ++V+ D+ E L AY + Sbjct: 879 DGALEFHGRLDNQVKIRGLRIEIGEIEHQLEDIDGVNEAVIAVIGDEASPERQLAAYISL 938 Query: 723 -AARTVSGAELREFLLKFLPAYMIPQHFMEIGKIPLMISGKLDVKALPPVTVTLVQPGET 781 A R ++ ++R L + LP++++P + + +P + +GK+D AL + + G Sbjct: 939 DAGRQLTVDDIRAALARQLPSHLVPALWTILPAMPHLPNGKIDRSALRALEIKGPD-GSG 997 Query: 782 RKPQDEVEEKLLEIWKKVLRIGDTGVQDGFFEMGGNSIQIMQLVYEINKCFPVSFQFTHF 841 P++ +EE+L IW+ VL+ V+ FFEMGG+S+ ++++ I F VS Sbjct: 998 TAPRNHIEERLAAIWQDVLQTSLIDVERSFFEMGGHSLLAIRIIARIKADFGVSLPLKAI 1057 Query: 842 IERQTIERIADFIKEAIQEERKEELPFIAADPANRHEPFPLTNVQMAYYLGRSSHFELGG 901 E TI +A+ ++ +E + + DP +RHEPFPLT++Q AY++GR+ FELG Sbjct: 1058 FETPTIAGLANRLENEAEEALNIDGLAVVHDPEDRHEPFPLTDIQHAYWIGRNKGFELGS 1117 Query: 902 VSTHSYLEMATELDIRRLNQ-CLNTLIQRHPALHTVYLPDATQQILPEVPEYTICEYDLS 960 V +H Y E + + +N L+ RH L + D Q++L +VP YT+ DL Sbjct: 1118 VGSHGYREFDIDDLDIDALENAINALVARHDMLRAIVDTDGRQRVLADVPHYTLPVADLR 1177 Query: 961 GYTEEAKNKRITKERDRMSHHIFNPNVWPLFEIVAFRSSPEESLLCISFDLLIMDAYSLE 1020 + A R+T R+R+SH+IF + WPLF I A R + + L +SFD+LI DA+SL+ Sbjct: 1178 DAVDRAS--RLTDIRNRLSHNIFKADHWPLFHIEAARLDGKTTRLFVSFDVLIGDAWSLK 1235 Query: 1021 ILQEEIMALYADRSLQLEELSITFRDYLVGYQQMKSGKWYLEDKEYWLQKVEDFPLAPGL 1080 ++ E+ AL R+L E+ +TFRDY++ + + Y +E+W ++ P +P L Sbjct: 1236 LMGTELAALMQKRAL--PEIGLTFRDYVLFEKSAHNSAAYERAREHWSARMATLPASPDL 1293 Query: 1081 PLLTQPQHVKNPYFKRKSKHYSQQHWRQLKQISQNHNLTPSAVLCTVYAEVLANWSNQPQ 1140 PL P +++P F R+ + W + K ++Q+ LTP+A + T++AEVLA WS + Sbjct: 1294 PLACNPSQIEHPRFTRRRGRLAATDWSRFKDVAQSAGLTPTAAIMTIFAEVLARWSRRQD 1353 Query: 1141 FGLNLTLFNRLPLHSDVDKLIGDFTSLLLLEVRMNPNDSFWEKAGNIQRVLMEALAHRHF 1200 F LNLT+FNR P+H DV+K++GDFT+ LLL + + +A +Q LME L HR F Sbjct: 1354 FTLNLTVFNREPVHQDVEKIVGDFTASLLLGLDFSARADLTTRARQVQLRLMEDLEHRLF 1413 Query: 1201 DGIDVMREISKRRALGNKALLPIVFTSALFDNGEDGGEAAENHGEASDGEQSTNGITQTS 1260 G+ V+RE++K+ AL+P+VFTS L G+A+ + + + ++QT Sbjct: 1414 SGVSVLRELAKQNGRSGGALMPVVFTSVL-------GQASRDDSAPRLDTRLVDSVSQTP 1466 Query: 1261 QVYLDNQVALIHGKMVINWDYISELFDPAVMDAMFAQYLSRIEAILYSREEMGFPALPAS 1320 QVYLD+QV+ G++V NWD + ELF P+++D MFA Y + + A+ + ++ + P Sbjct: 1467 QVYLDHQVSEDQGELVYNWDAVEELFPPSMLDMMFAAYETLLRAL--ANDDAAWQTEP-- 1522 Query: 1321 DYTSIQAY----NHTEEPIPSKT--LHGLFEEAVHQTPYAVAIEADNLSITYKELDDRAD 1374 D QA+ N + +P T LH F E ++P +A+ A + +TY ++ +RA Sbjct: 1523 DIVDCQAFETLNNRAKIALPDDTRLLHEAFFERAAESPEKIAVCAGGIELTYGQVAERAL 1582 Query: 1375 KVAGSLRSLGVSAGDRVGVIARKEIATFINILGILKSGAAYVPIDPEYPQERVDYIRNHS 1434 +A SL+ G DRV V K I LGIL SGAAYVP+DPE P ER + + Sbjct: 1583 ALAASLQKAGAGPNDRVAVSLPKGADQVIACLGILASGAAYVPVDPELPAERRFELVEDT 1642 Query: 1435 QCKLVL-ETDYYEKNCR--------GQHPAELQRHNLPESLAYVIYTSGSTGNPKGVMIS 1485 LV+ E + + R G P+ P LAY+I+TSGSTG PKGVMI Sbjct: 1643 AADLVIAEGGDWPQRVRVIAVPEEGGARPSP--SSTTPSDLAYIIFTSGSTGKPKGVMID 1700 Query: 1486 HQAACNTVQDINQKFQVGAADRMLGISSLCFDLSVYDIFGAFAAGATLVL-VKDQ-KDIR 1543 H+ A NT+ DIN++F V A DR+ +SSL FDLSVYDIFG A G +V+ V+++ D Sbjct: 1701 HRGALNTILDINRRFAVSAEDRVFALSSLSFDLSVYDIFGPLAVGGAIVIPVREEVSDNA 1760 Query: 1544 QLADTLSAQKITIWNSVPAIMDRVGSEIRAQGIYQENLDLRLVLLSGDWIPLHLPETVKQ 1603 + L ++T+WNSVPA+ + +E LR++++SGDWIP+ LP +K Sbjct: 1761 RWMKLLLQHRVTVWNSVPALAQ---LLLAELPALREKPPLRMIMMSGDWIPVSLPPALKA 1817 Query: 1604 LFPAAKLISCGGATEASIWSIYYPIDEVMPQWTSIPYGMPLANQQFYVLNQQMDYCPLEV 1663 P A LIS GGATEASIWSI++PI E + WTSIPYG PLANQ++YVL+ Q CP V Sbjct: 1818 QLPDADLISLGGATEASIWSIFHPIGEALRDWTSIPYGQPLANQRWYVLDDQGRPCPPWV 1877 Query: 1664 SGELYIGGSGVANGYLNDPEKPSHSFI-----HHPELG----YIYRTGDYGVLHRDGCIE 1714 +G L+IGG GVA GY P+ + FI E G +Y TGD G L +G +E Sbjct: 1878 TGRLFIGGIGVARGYWGRPQLTAERFIPDSFADEEEAGNGALLLYETGDLGRLRPEGLLE 1937 Query: 1715 FLGRKDQQVKVGGYRIELGEVEAQLLRCGGVRHAVVLAADGEDKRLGAYLIPDSQSA 1771 FLGR+D QVKV G+RIELGE+E LL+ V AVV G+ L AY++PD++ + Sbjct: 1938 FLGREDFQVKVNGFRIELGEIETALLQNENVAEAVVTTM-GQPPALIAYIVPDTKGS 1993 Score = 333 bits (853), Expect = 3e-89, Method: Compositional matrix adjust. Identities = 300/1120 (26%), Positives = 521/1120 (46%), Gaps = 125/1120 (11%) Query: 881 PLTNVQMAYYLGRSSHFELGGVSTHSYLEMATELDIRRLNQCLNTLIQRHPALHTVYLPD 940 PL+ Q + + E + S L +LD L + L +++RH L T ++P Sbjct: 47 PLSFAQQRLWFMQQLEPENTAYNMRSILRFRGKLDRAALEEALANVVKRHEPLRTRFVPG 106 Query: 941 ATQQILPEVP-----EYTICEYDLSGYTE-EAKNKRITKERDRMSHHIFNPNVWPLFEIV 994 A PE+ + I DL ++ EA ++ +R + + + +P + ++ Sbjct: 107 ADG--FPELDILAAGDAEIEFLDLGQDSDAEATARQHVLQRLSVPYDLSHPQL----RVM 160 Query: 995 AFRSSPEESLLCISFDLLIMDAYSLEILQEEIMALYADRSLQ---LEELSITFRDYLVGY 1051 R S E+ LL + + D +S+ +L ++ Y DR+ Q L ++ + + D+ + Sbjct: 161 LVRLSAEDHLLAVGLHHIAGDRWSMTVLARDLAGFYKDRTGQSHHLPDIRVQYADWAIWQ 220 Query: 1052 QQMKSGKWYLEDKEYWLQKVEDFPLAPGLPLLTQPQHVKNPYF-----KRKSKHYSQQHW 1106 +M G YW + L LP+L P P + + Sbjct: 221 GKMLRGPVLENQLAYWKKA-----LGTDLPVLDLPFDRPRPAIASFLGAQFAVSVDPALS 275 Query: 1107 RQLKQISQNHNLTPSAVLCTVYAEVLANWSNQPQFGLNLTLFNRLPLHSDVDKLIGDFTS 1166 +L+ +++ HN++ +L + + VL + + + + NR + +IG + Sbjct: 276 GELRALARAHNVSLYVLLLSAFKLVLHLYCDSDDIVVGSEVANR--DRPETQAMIGPLVN 333 Query: 1167 LLLLEVRMNPNDSFWEKAGNIQRV---LMEALAHRHFDGIDVMREISKRRALGNKALLPI 1223 L+L + N F +G +QRV + LA++ ++ ++ +R+L + P+ Sbjct: 334 TLVLRTDLAGNPDF---SGLLQRVSETVRTGLANQDVPYERIVEALNPKRSLSE--MTPL 388 Query: 1224 VFTSALFDNGEDGGEAAENHGEASDGEQSTNGITQTS-QVYLDNQVALIHGKMVINWDYI 1282 A FD + E G A + + +G + + L++ I GK+ +Y Sbjct: 389 F--QAKFDLQHNLARLPELDGLAIETLRLPDGAAKNEIRFNLEDNDPDIGGKI----EYA 442 Query: 1283 SELFDPAVMDAMFAQYLSRIEAILYSREEMGFPALPASDYTSIQAYNHTEEPIPSKT--- 1339 ++LF+ + A R E +L + E PA S++ S+ + +E I Sbjct: 443 TDLFN----EETVATIWRRFEDVLRTIAED--PARRLSEF-SLLCDDEQQEQIRRSAGQA 495 Query: 1340 -------LHGLFEEAVHQTPYAVAIEADNLSITYKELDDRADKVAGSLRSLGVSAGDRVG 1392 LH + +TP A+ +++ +TY+ELD R+D +A +L + G G VG Sbjct: 496 LTQSGLCLHEMLTAQATRTPEKSAVASEHGKLTYRELDQRSDAIAAALAASGFGRGSIVG 555 Query: 1393 VIARKEIATFINILGILKSGAAYVPIDPEYPQERVDYIRNHSQCKLVL-ETDYYEKNCR- 1450 V ++ + G+LK+GAAYVP+DP+YP ER+ +I + ++VL ++D + Sbjct: 556 VCMQRTPDLIAALFGVLKAGAAYVPLDPDYPSERLAFIAQDAAIRVVLTDSDRLAFDATV 615 Query: 1451 -------GQHPAEL--QRHNL-PESLAYVIYTSGSTGNPKGVMISHQAACNTVQDINQKF 1500 G+ P + H P LAY+IYTSGSTG PKGV I+H A +Q F Sbjct: 616 DLMLLEVGKLPDAVFSAAHACDPADLAYIIYTSGSTGRPKGVAITHGNAAARMQWTANNF 675 Query: 1501 QVGAADRMLGISSLCFDLSVYDIFGAFAAGATLVLVKDQKDIRQLADTLSAQKITIWNSV 1560 +L +S+CFDLS+++IFG + G +VL D+ +L + ++++ N+V Sbjct: 676 TSDELASVLASTSVCFDLSIFEIFGTLSCGGQVVLANTLFDLPRLQHVV---EVSLINTV 732 Query: 1561 PAIM------DRVGSEIRAQGIYQENLDLRLVLLSGDWIPLHLPETVKQLFPAAKLISCG 1614 P+++ D + + + A V L+G+ +P L E + + P A++ + Sbjct: 733 PSLLREYLRHDALPTSVSA------------VNLAGEPLPPVLLEELAKKAPQARIHNLY 780 Query: 1615 GATEASIWSIYYPIDEVMPQWTSIPYGMPLANQQFYVLNQQMDYCPLEVSGELYIGGSGV 1674 G +E + +S + V + T + G PL Q YVL++ P ++GELY+GG+GV Sbjct: 781 GPSEDTTYSTGAMVRAVSGEKT-VSIGAPLPGTQAYVLDRAGRLRPDGLAGELYLGGAGV 839 Query: 1675 ANGYLNDPEKPSHSFIHHPELG----YIYRTGDYGVLHRDGCIEFLGRKDQQVKVGGYRI 1730 GYL P + + F+ G Y+YRTGD DG +EF GR D QVK+ G RI Sbjct: 840 TRGYLRRPSQTAERFVPDAFSGRSSSYLYRTGDRVRRRADGALEFHGRLDNQVKIRGLRI 899 Query: 1731 ELGEVEAQLLRCGGVRHAVVLAADGE---DKRLGAYLIPDSQSADQAAFINEVRARIAKV 1787 E+GE+E QL GV AV+ E +++L AY+ S A + ++++RA +A+ Sbjct: 900 EIGEIEHQLEDIDGVNEAVIAVIGDEASPERQLAAYI---SLDAGRQLTVDDIRAALARQ 956 Query: 1788 LPDYMIPHYFVVLEQFPLTANGKMDVQALLKLQPAGNKQTSAYTAPRNDVEERIVNIFKE 1847 LP +++P + +L P NGK+D AL L+ G + TAPRN +EER+ I+++ Sbjct: 957 LPSHLVPALWTILPAMPHLPNGKIDRSALRALEIKGPDGSG--TAPRNHIEERLAAIWQD 1014 Query: 1848 LLEADQVGTLDNFFEMGINSVQIAMINNKLKQEFQKEIPLLTLFEYANIHALAGYLSG-- 1905 +L+ + +FFEMG +S+ I ++K +F +PL +FE I LA L Sbjct: 1015 VLQTSLIDVERSFFEMGGHSLLAIRIIARIKADFGVSLPLKAIFETPTIAGLANRLENEA 1074 Query: 1906 ---------------NDQNEP---DDVPQEQQVTRNQGKE 1927 D++EP D+ + RN+G E Sbjct: 1075 EEALNIDGLAVVHDPEDRHEPFPLTDIQHAYWIGRNKGFE 1114 Score = 98.6 bits (244), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 71/225 (31%), Positives = 110/225 (48%), Gaps = 23/225 (10%) Query: 1704 YGVLHRDGCIEFLGRKDQQVKVGGYRIELGEVEAQLLRCGGVRH---AVVLAADGEDKRL 1760 YG RD C+ G Q + + R+++G L GGV A LA + +++ L Sbjct: 2149 YGQKSRDFCLLEAGHMAQTMMLHAPRLDIG-----LCAAGGVDLTAIASALATEEDEEPL 2203 Query: 1761 ----GAYLIPDSQSADQAA-------FINEVRARIAKVLPDYMIPHYFVVLEQFPLTANG 1809 G + P + QA+ +RA +A LP YM+P FV++E+ PL+ANG Sbjct: 2204 YVLAGGSIDPAWSTQWQASAQMRGETLSERLRAFLAGKLPAYMVPREFVIMERLPLSANG 2263 Query: 1810 KMDVQALLKLQPAGNKQTSAYTAPRNDVEERIVNIFKELLEADQVGTLDNFFEMGINSVQ 1869 K+D QAL PA + AP + E ++ I+ ELL +D G DNFFE G +S+ Sbjct: 2264 KVDRQAL----PAPGGRARQTVAPATENESALLAIWHELLSSDSAGVEDNFFEAGGDSLT 2319 Query: 1870 IAMINNKLKQEFQKEIPLLTLFEYANIHALAGYLSGNDQNEPDDV 1914 I + ++++QEF + L LF + A + L + PD+ Sbjct: 2320 IMQLLSRIRQEFSVHLTLAQLFGATTVKAQSELLGSLSPSLPDEA 2364 Score = 86.3 bits (212), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 47/121 (38%), Positives = 66/121 (54%), Gaps = 11/121 (9%) Query: 732 LREFLLKFLPAYMIPQHFMEIGKIPLMISGKLDVKALPPVTVTLVQPG----ETRKPQDE 787 LR FL LPAYM+P+ F+ + ++PL +GK+D +ALP PG +T P E Sbjct: 2234 LRAFLAGKLPAYMVPREFVIMERLPLSANGKVDRQALP-------APGGRARQTVAPATE 2286 Query: 788 VEEKLLEIWKKVLRIGDTGVQDGFFEMGGNSIQIMQLVYEINKCFPVSFQFTHFIERQTI 847 E LL IW ++L GV+D FFE GG+S+ IMQL+ I + F V T+ Sbjct: 2287 NESALLAIWHELLSSDSAGVEDNFFEAGGDSLTIMQLLSRIRQEFSVHLTLAQLFGATTV 2346 Query: 848 E 848 + Sbjct: 2347 K 2347 >sp|O30409|TYCC_BREPA Tyrocidine synthetase III [Includes: ATP-dependent asparagine adenylase (AsnA) (Asparagine activase); ATP-dependent glutamine adenylase (GlnA) (Glutamine activase); ATP-dependent tyrosine adenylase (TyrA) (Tyrosine activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase)] pir||T31076 tyrocidine synthetase 3 - Brevibacillus brevis gb|AAC45930.1| tyrocidine synthetase 3 [Brevibacillus brevis] Length = 6486 Score = 970 bits (2508), Expect = 0.0, Method: Compositional matrix adjust. Identities = 634/1974 (32%), Positives = 991/1974 (50%), Gaps = 125/1974 (6%) Query: 14 YWLETFSGEIPLLHLPADHSRPAFKTYRGSAEMFSIPKEQVLEIKQLAAEQEATLYMVLF 73 +WL TF+ EIPLL+LP D+ RP+ +++ G +F+ KE + ++Q+A+E TLYM+L Sbjct: 1234 HWLNTFADEIPLLNLPTDYPRPSVQSFAGDLVLFAAGKELLERLQQVASETGTTLYMILL 1293 Query: 74 AVWNILLAKLSDQEEIIVGVPTSGRNHSDIEHVIGMFVNTLPIKSRISAKLTFAEILHAM 133 A +N+LL+K + QE+IIVG P +GR+H+D+E+++G+FVNTL ++++ ++ TFA+ L + Sbjct: 1294 AAYNVLLSKYTGQEDIIVGTPVAGRSHADVENIMGIFVNTLALRNQPASSKTFAQFLQEV 1353 Query: 134 KANISNALEHQDYPFEDLVSQLQITRDFGRNPLFDVMFXXXXXXXXXXXXXXXXXXELQM 193 K N A +HQDYPFE+LV +L I RD RNPLFD +F EL Sbjct: 1354 KQNALAAYDHQDYPFEELVEKLAIQRDISRNPLFDTLFSLENANQQSLAIA-----ELTA 1408 Query: 194 KPYPYTTTTSRFDLTLDGEERAGELVFTLEYATDLFTRETVMRLIRYFRTILLEVLKHPA 253 PY S+FDL L+ E ++ F L +AT LF +ETV R+ R++ IL + + P Sbjct: 1409 SPYELFNKISKFDLALNASESPADIQFQLTFATKLFKKETVERMARHYLEILRWISEQPT 1468 Query: 254 QKTGLIHLPDNQETDRLLNRFNQTAGEYPEHLTVHQLFAARVKEHPHQAAVTFRNQSITY 313 I + E LL N T E +HQL + P + AV + ++TY Sbjct: 1469 ASLADIDMMTEAEKRTLLLNVNDTFVERTAATALHQLVEEQAARTPDEVAVVYEEYALTY 1528 Query: 314 DELNXXXXXXXXXXXXXGIGPDQIVALITTRSVDMXXXXXXXXXXXXXXXPIDPGLPANR 373 ELN G GPD ++ ++ RS M PIDP P R Sbjct: 1529 RELNARANQLARLLRSHGTGPDTLIGIMVDRSPGMVVGMLAVLKAGGAYTPIDPSYPPER 1588 Query: 374 IAYMLDDAGVQVILTNTSVEN----QGNRIVLDMRSLGLDHGAPLPVPPVHSSRNLAYCM 429 I YML D+ ++LT ++ QG ++D+ + GA + V +LAY + Sbjct: 1589 IQYMLSDSQAPILLTQRHLQELAAYQGE--IIDVDEEAIYTGADTNLDNVAGKDDLAYVI 1646 Query: 430 YTSGTTGLPKGILVEHRSLLNFFSAISDVLSFGKGETFLSLTTVSFDIFWLESILPLLAG 489 YTSG+TG PKG+++ H+++ N + + + L T SFD E LPL+ G Sbjct: 1647 YTSGSTGNPKGVMISHQAICNHMLWMRETFPLTTEDAVLQKTPFSFDASVWEFYLPLITG 1706 Query: 490 YQLVIADELQQKDVHALLALVKQAEISVMQTTPSRXXXXXXXXXXXXXXXXXRYLLIGGE 549 QLV+A +D+ + L++ +I+ +Q PS R + GGE Sbjct: 1707 GQLVLAKPDGHRDIAYMTRLIRDEKITTLQMVPSLLDLVMTDPGWSACTSLQR-VFCGGE 1765 Query: 550 PLPQALAEQARSILPGGRIFNLYGPTETTI----WSTAQEVTAGPVNIGKPLKNTQVYIL 605 L AL + ++ NLYGPTETTI W ++ + IGKP+ N ++Y++ Sbjct: 1766 ALTPALVSRFYET-QQAQLINLYGPTETTIDATYWPCPRQQEYSAIPIGKPIDNVRLYVV 1824 Query: 606 NDELLLQPIGVPGILYIGGHGVVRGYQNNPELTAQRFIDNPYRPGEQIYCTGDIARWTEE 665 N LQP+GV G L I G G+ RGY ELT F+DNP+ PG +Y TGD+ R+ + Sbjct: 1825 NASNQLQPVGVAGELCIAGDGLARGYWQREELTKASFVDNPFEPGGTMYRTGDMVRYLPD 1884 Query: 666 GTIEYLGRADFQVKIRGYRIELAEIEQQLDTHPAIEKSVVRAQRDDQDEPMLVAYYTAAR 725 G IEYLGR D QVKIRG+RIEL EIE L H A++ VV A++D + + L AY A + Sbjct: 1885 GHIEYLGRIDHQVKIRGHRIELGEIEATLLQHEAVKAVVVMARQDGKGQNSLYAYVVAEQ 1944 Query: 726 TVSGAELREFLLKFLPAYMIPQHFMEIGKIPLMISGKLDVKALPPVTVTLVQPGETRKPQ 785 + AELR +L LPAYM+P F+ + ++PL +GK+D KALP P+ Sbjct: 1945 DIQTAELRTYLSATLPAYMVPSAFVFLEQLPLSANGKVDRKALPQPEDAAASAAVYVAPR 2004 Query: 786 DEVEEKLLEIWKKVLRIGDTGVQDGFFEMGGNSIQIMQLVYEINKCFPVSFQFTHFIERQ 845 +E E KL IW+ VL + GV D FFE+GG+S++ M ++ + + F V E Sbjct: 2005 NEWEAKLAAIWESVLGVEPIGVHDHFFELGGHSLKAMHVISLLQRSFQVDVPLKVLFESP 2064 Query: 846 TIERIADFIKEAIQEERKEELPFIAADPANRHEPFPLTNVQMAYYLGRSSHFELGGVSTH 905 TI +A + A RK + A P + E +P++ Q ++ + E G+S + Sbjct: 2065 TIAGLAPLVAAA----RKGT--YTAIPPVEKQEYYPVSAAQKRMFILQ--QMEGAGISYN 2116 Query: 906 --SYLEMATELDIRRLNQCLNTLIQRHPALHTVYLPDATQQILPEVPEYTICEYDLS--- 960 ++ + +LD RL Q L +L+QRH +L T + + E + + DL+ Sbjct: 2117 MPGFMYLDGKLDTERLQQALKSLVQRHESLRTSF-----HSVQGETVQRVHDDVDLAISF 2171 Query: 961 GYTEEAKNKRITKERDRMSHHIFNPNVWPLFEIVAFRSSPEESLLCISFDLLIMDAYSLE 1020 G EA+ ++I ++ + F+ PL + +PE L + +++D S+ Sbjct: 2172 GEATEAETRQIAEQFIQP----FDLGTAPLLRAGLIKLAPERHLFMLDLHHIVVDGVSIG 2227 Query: 1021 ILQEEIMALYADRSLQLEELSITFRDYLVGYQQMKSGKWYLEDKEYWLQKVEDFPLAPGL 1080 +L EE LY +L L I ++D+ Q + + E + YWL + Sbjct: 2228 LLIEEFAQLYHGE--ELPALRIQYKDFAKWQQDWFQTEEFAEQEAYWLNT-----FTGEI 2280 Query: 1081 PLLTQPQHVKNPYFK-----RKSKHYSQQHWRQLKQISQNHNLTPSAVLCTVYAEVLANW 1135 P+L P P K R +QL Q++Q T VL Y +L+ + Sbjct: 2281 PVLNLPTDYPRPSVKSFAGDRFVFGSGTALPKQLHQLAQETGTTLYMVLLAAYNVLLSKY 2340 Query: 1136 SNQPQFGLNLTLFNRLPLHSDVDKLIGDFTSLLLLEVRMNPNDSFWEKAGNIQRVLMEAL 1195 S Q + R H++ + ++G F + L L +F + ++ + A Sbjct: 2341 SRQEDIIVGAPTAGR--SHAETESIVGMFVNTLALRNEPAGGKTFRDFLAEVKINTLGAF 2398 Query: 1196 AHRHFDGIDVMREISKRRALGNKALLPIVFTSALFDNGEDGG-EAAENHGEASDGEQSTN 1254 H+ + +++ ++ +R L L VF + N E E + E Sbjct: 2399 EHQDYPLDELVDKLDMQRDLSRNPLFDTVF---ILQNMEQKPFEMEQLTITPYSAEVKQA 2455 Query: 1255 GITQTSQVYLDNQVALIHGKMVINWDYISELFDPAVMDAMFAQYLSRIEAILYSREEMGF 1314 + + Y +N +++ + DY ++LF ++ + ++ + A++ Sbjct: 2456 KFDLSLEAYEEN------AEIIFSLDYSTKLFSRETIEKIATHFIQILRAVIAE------ 2503 Query: 1315 PALPASDYTSIQA---------YNHTEEPIP-SKTLHGLFEEAVHQTPYAVAIEADNLSI 1364 P +P S+ T + +N + P +KTL LFEE ++P A A+E + Sbjct: 2504 PEMPLSEITMLTEAEKQRLLVDFNGAHKDFPQNKTLQALFEEQAEKSPQATAVEISGQPL 2563 Query: 1365 TYKELDDRADKVAGSLRSLGVSAGDRVGVIARKEIATFINILGILKSGAAYVPIDPEYPQ 1424 +Y+EL++RA+++A +LR GV VG++A + + + IL ILK+G AYVPIDPEYP+ Sbjct: 2564 SYQELNERANQLAATLRERGVQPDQPVGIMANRSVEMVVGILAILKAGGAYVPIDPEYPE 2623 Query: 1425 ERVDYIRNHSQCKLVLETDYY----------------EKNCRGQHPAELQRHNLPESLAY 1468 ERV Y+ Q +LVL + +++ G H + LQ N LAY Sbjct: 2624 ERVAYMLTDCQARLVLTQKHLGAKLGSSVTAECLYLDDESNYGVHRSNLQPINTASDLAY 2683 Query: 1469 VIYTSGSTGNPKGVMISHQAACNTVQDINQKFQVGAADRMLGISSLCFDLSVYDIFGAFA 1528 +IYTSG+TG PKGVM+ H+ N V ++Q+ DR L S FD V F Sbjct: 2684 IIYTSGTTGKPKGVMVEHRGIVNNVLWKKAEYQMKVGDRSLLSLSFAFDAFVLSFFTPVL 2743 Query: 1529 AGATLVLVKDQ--KDIRQLADTLSAQKITIWNSVPAIMDRV-----GSEIRAQGIYQENL 1581 +GAT+VL +D+ KD L ++A + T+ VP++ + ++IR Sbjct: 2744 SGATVVLAEDEEAKDPVSLKKLIAASRCTLMTGVPSLFQAILECSTPADIRP-------- 2795 Query: 1582 DLRLVLLSGDWIPLHLPETVKQLFPAAKLISCGGATEASIWSIYYPIDEVMPQWTSIPYG 1641 L+ V L G+ I L E KQL P +++ G TE+S+ + + + +I G Sbjct: 2796 -LQTVTLGGEKITAQLVEKCKQLNPDLVIVNEYGPTESSVVATW---QRLAGPDAAITIG 2851 Query: 1642 MPLANQQFYVLNQQMDYCPLEVSGELYIGGSGVANGYLNDPEKPSHSFIHHPELG--YIY 1699 P+AN Y++NQ P+ V GE+ IGG G+A GY N P F+ HP +Y Sbjct: 2852 RPIANTSLYIVNQYHQLQPIGVVGEICIGGRGLARGYWNKPALTEEKFVSHPFAAGERMY 2911 Query: 1700 RTGDYGVLHRDGCIEFLGRKDQQVKVGGYRIELGEVEAQLLRCGGVRHAVVLAADGEDKR 1759 +TGD G DG IE++GR D+QVKV GYRIE+GE+E+ LL + AVV+ + + Sbjct: 2912 KTGDLGKWLPDGTIEYIGRIDEQVKVRGYRIEIGEIESALLAAEKLTAAVVVVY---EDQ 2968 Query: 1760 LGAYLIPDSQSADQAAFINEVRARIAKVLPDYMIPHYFVVLEQFPLTANGKMDVQALLKL 1819 LG + +AD+ + ++ + ++K LP YMIP +FV L+Q PLT NGK+D +AL K Sbjct: 2969 LGQSALAAYFTADEQLDVTKLWSHLSKRLPSYMIPAHFVQLDQLPLTPNGKVDKKALPK- 3027 Query: 1820 QPAGNKQTSA-YTAPRNDVEERIVNIFKELLEADQVGTLDNFFEMGINSVQIAMINNKLK 1878 P G T A Y AP N VE ++ I++ +L +G LDNFF++G +S++ + ++ Sbjct: 3028 -PEGKPVTEAQYVAPTNAVESKLAEIWERVLGVSGIGILDNFFQIGGHSLKAMAVAAQVH 3086 Query: 1879 QEFQKEIPLLTLFEYANIHALAGYL--SGNDQNEP-DDVPQEQQVTRNQGKERM 1929 +E+Q E+PL LF I ALA Y+ SG + P + P ++ + ++RM Sbjct: 3087 REYQVELPLKVLFAQPTIKALAQYVATSGKETYVPIEPAPLQEYYPVSSAQKRM 3140 Score = 966 bits (2497), Expect = 0.0, Method: Compositional matrix adjust. Identities = 639/1944 (32%), Positives = 1002/1944 (51%), Gaps = 116/1944 (5%) Query: 14 YWLETFSGEIPLLHLPADHSRPAFKTYRGSAEMFSIPKEQVLEIKQLAAEQEATLYMVLF 73 YWL FSG+IP+L+LPAD SRP +++ G F K + ++ +LA E ++TL+MVL Sbjct: 3309 YWLNAFSGDIPVLNLPADFSRPLTQSFEGDCVSFQADKALLDDLHKLAQESQSTLFMVLL 3368 Query: 74 AVWNILLAKLSDQEEIIVGVPTSGRNHSDIEHVIGMFVNTLPIKSRISAKLTFAEILHAM 133 A +N+LLAK S QE+I+VG P +GR+H+DIE+V+GMFVNTL +++ F L + Sbjct: 3369 AAYNVLLAKYSGQEDIVVGTPIAGRSHADIENVLGMFVNTLALRNYPVETKHFQAFLEEV 3428 Query: 134 KANISNALEHQDYPFEDLVSQLQITRDFGRNPLFDVMFXXXXXXXXXXXXXXXXXXELQM 193 K N A HQDYPFE LV +L I RD RNPLFD MF L++ Sbjct: 3429 KQNTLQAYAHQDYPFEALVEKLDIQRDLSRNPLFDTMFILQNLDQKAYELDG-----LKL 3483 Query: 194 KPYPYTTTTSRFDLTLDGEERAGELVFTLEYATDLFTRETVMRLIRYFRTILLEVLKHPA 253 + YP ++FDLTL+ E + F L Y+T LF RE++ R+ +F +L +V+ A Sbjct: 3484 EAYPAQAGNAKFDLTLEAHEDETGIHFALVYSTKLFQRESIERMAGHFLQVLRQVVADQA 3543 Query: 254 QKTGLIHLPDNQETDRLLNRFNQTAGEYPEHLTVHQLFAARVKEHPHQAAVTFRNQSITY 313 I L +E + FN T YP LT+ +LF + + P AAV Q +TY Sbjct: 3544 TALREISLLSEEERRIVTVDFNNTFAAYPRDLTIQELFEQQAAKTPEHAAVVMDGQMLTY 3603 Query: 314 DELNXXXXXXXXXXXXXGIGPDQIVALITTRSVDMXXXXXXXXXXXXXXXPIDPGLPANR 373 ELN G+G + IV L+ RS++M +DP P+ R Sbjct: 3604 RELNEKANQLAHVLRQNGVGKESIVGLLADRSLEMITGIMGILKAGGAYLGLDPEHPSER 3663 Query: 374 IAYMLDDAGVQVILTNTS----VENQGNRIVLDMRSLG-LDHGAPLPVPPVHSSRNLAYC 428 +AYML+D GV+V+L V IVL+ SL D G P V+ + +LAY Sbjct: 3664 LAYMLEDGGVKVVLVQKHLLPLVGEGLMPIVLEEESLRPEDCGNP---AIVNGASDLAYV 3720 Query: 429 MYTSGTTGLPKGILVEHRSLLNFFSAISDVLSFGKGETFLSLTTVSFDIFWLESILPLLA 488 MYTSG+TG PKG++VEHR++ ++ + + + + + FD E LL Sbjct: 3721 MYTSGSTGKPKGVMVEHRNVTRLVMH-TNYVQVRESDRMIQTGAIGFDAMTFEIFGALLH 3779 Query: 489 GYQLVIADELQQKDVHALLALVKQAEISVMQTTPSRXXXXXXXXXXXXXXXXXRYLLIGG 548 G L + + D L ++ +I+ M T R L++GG Sbjct: 3780 GASLYLVSKDVLLDAEKLGDFLRTNQITTMWLTSP--LFNQLSQDNPAMFDSLRALIVGG 3837 Query: 549 EPLPQALAEQARSILPGGRIFNLYGPTETTIWSTA---QEVTAGPVNIGKPLKNTQVYIL 605 E L + +S LP I+N YGPTE T +ST ++ + IGKP+ N+ YI+ Sbjct: 3838 EALSPKHINRVKSALPDLEIWNGYGPTENTTFSTCYLIEQHFEEQIPIGKPIANSTAYIV 3897 Query: 606 NDELLLQPIGVPGILYIGGHGVVRGYQNNPELTAQRFIDNPYRPGEQIYCTGDIARWTEE 665 + QPIGVPG L +GG GV RGY N PELTA++F+ NP+ PGE +Y TGD+ARW + Sbjct: 3898 DGNNQPQPIGVPGELCVGGDGVARGYVNKPELTAEKFVPNPFAPGETMYRTGDLARWLPD 3957 Query: 666 GTIEYLGRADFQVKIRGYRIELAEIEQQLDTHPAIEKSVVRAQRDDQDEPMLVAYYTAAR 725 GTIEYLGR D QVKIRGYRIEL EIE L ++++VV + + L AY+ + Sbjct: 3958 GTIEYLGRIDQQVKIRGYRIELGEIETVLSQQAQVKEAVVAVIEEANGQKALCAYFVPEQ 4017 Query: 726 TVSGAELREFLLKFLPAYMIPQHFMEIGKIPLMISGKLDVKALPPVTVTLVQPGETRKPQ 785 V AELRE + K LP YM+P +++++ K+PL +GK+D +ALP + Q Sbjct: 4018 AVDAAELREAMSKQLPGYMVPAYYVQMEKLPLTANGKVDRRALPQPSGERTTGSAFVAAQ 4077 Query: 786 DEVEEKLLEIWKKVLRIGDTGVQDGFFEMGGNSIQIMQLVYEINKCFPVSFQFTHFIERQ 845 ++ E KL +IW++VL I G+ D FFE+GG+S++ M ++ +++K F V Sbjct: 4078 NDTEAKLQQIWQEVLGIPAIGIHDNFFEIGGHSLKAMNVITQVHKTFQVELPLKALFATP 4137 Query: 846 TIERIADFIKEAIQEERKEELPFIAADPANRHEPFPLTNVQMAYYLGRSSHFELGGVSTH 905 TI +A I E+ E+ F P +P++ Q Y+ FE G+S + Sbjct: 4138 TIHELAAHIAESAFEQ------FETIQPVEPAAFYPVSFAQKRMYI--LHQFEGSGISYN 4189 Query: 906 --SYLEMATELDIRRLNQCLNTLIQRHPALHTVYLP---DATQQILPEVPEYTICEYDLS 960 S L + +LD R + +L++RH +L T + + Q++ P+V E + + + Sbjct: 4190 VPSVLVLEGKLDYDRFAAAIQSLVKRHESLRTSFHSVNGEPLQRVHPDV-ELPVRLLEAT 4248 Query: 961 GYTEEAKNKRITKERDRMSHHIFNPNVWPLFEIVAFRSSPEESLLCISFDLLIMDAYSLE 1020 E+ + + + F+ + PLF + + E L + +I D SL Sbjct: 4249 EDQSESLIQELIQP--------FDLEIAPLFRVNLIKLGAERHLFFMDMHHIISDGVSLA 4300 Query: 1021 ILQEEIMALYADRSLQLEELSITFRDYLVGYQQMKSGKWYLEDKEYWLQKVEDFPLAPGL 1080 ++ EEI +LYA + QL +L I ++D+ V ++ + + +++W + A + Sbjct: 4301 VIVEEIASLYAGK--QLSDLRIQYKDFAVWQTKLAQSDRFQKQEDFWTRT-----FAGEI 4353 Query: 1081 PLLTQPQHVKNP---YFKRKSKHYSQQH--WRQLKQISQNHNLTPSAVLCTVYAEVLANW 1135 PLL P P F + H QL++++ T VL Y +L+ + Sbjct: 4354 PLLNLPHDYPRPSVQSFDGDTVALGTGHHLLEQLRKLAAETGTTLFMVLLAAYHVLLSKY 4413 Query: 1136 SNQPQFGLNLTLFNRLPLHSDVDKLIGDFTSLLLLEVRMNPNDSFWEKAGNIQRVLMEAL 1195 + Q + + + R H+DV++++G F + L L+ + SF ++++ + A Sbjct: 4414 AGQEEIVVGTPIAGR--SHADVERIVGMFVNTLALKNTAAGSLSFRAFLEDVKQNALHAF 4471 Query: 1196 AHRHFDGIDVMREISKRRALGNKALLPIVFTSALFDNGEDGGEAAENHGEASDGEQS--- 1252 H+ + ++ ++ RR L L +F+ L ++ E GE +D + S Sbjct: 4472 EHQDYPFEHLVEKLQVRRDLSRNPLFDTMFSLGLAESAE---------GEVADLKVSPYP 4522 Query: 1253 TNGITQTSQVYLDNQVALIHGKMVINWDYISELFDPAVMDAMFAQYLSRIEAILYSRE-E 1311 NG + LD +++ + Y ++LF +D + A Y+ ++ I + E Sbjct: 4523 VNGHIAKFDLSLDAMEK--QDGLLVQFSYCTKLFAKETVDRLAAHYVQLLQTITADPDIE 4580 Query: 1312 MGFPALPASDYTS--IQAYNHTEEPIPS-KTLHGLFEEAVHQTPYAVAIEADNLSITYKE 1368 + ++ + T + ++ T+ P+ KT LFEE V +TP +A+ N +TY+E Sbjct: 4581 LARISVLSKAETEHMLHSFLATKTAYPTDKTFQKLFEEQVEKTPNEIAVLFGNEQLTYQE 4640 Query: 1369 LDDRADKVAGSLRSLGVSAGDRVGVIARKEIATFINILGILKSGAAYVPIDPEYPQERVD 1428 L+ +A+++A LR GV VG++ + + I +L +LK+G +VPIDP+YP ER Sbjct: 4641 LNAKANQLARVLRRKGVKPESTVGILVDRSLYMVIGMLAVLKAGGTFVPIDPDYPLERQA 4700 Query: 1429 YIRNHSQCKLVL-------------ETDYYEKNCRGQ-HPAELQRHNLPESLAYVIYTSG 1474 ++ S+ KL+L ET Y + Q L+ PE++AY+IYTSG Sbjct: 4701 FMLEDSEAKLLLTLQKMNSQVAFPYETFYLDTETVDQEETGNLEHVAQPENVAYIIYTSG 4760 Query: 1475 STGNPKGVMISHQAACNTVQDINQKFQVGAAD-RMLGISSLCFDLSVYDIFGAFAAGATL 1533 +TG PKGV+I H++ N ++ + + R+L ++S FD+S D A G L Sbjct: 4761 TTGKPKGVVIEHRSYANVAFAWKDEYHLDSFPVRLLQMASFAFDVSTGDFARALLTGGQL 4820 Query: 1534 VLVKD--QKDIRQLADTLSAQKITIWNSVPAIMDRVGSEIRAQGIYQENLD---LRLVLL 1588 V+ + + D L +T+ +ITI+ + PA++ + +Y+ LD ++L++L Sbjct: 4821 VICPNGVKMDPASLYETIRRHEITIFEATPALIMPL-----MHYVYENELDMSQMKLLIL 4875 Query: 1589 SGDWIPLHLPETVKQLF-PAAKLISCGGATEASIWSIYYPIDEVMP-QWTSIPYGMPLAN 1646 D P +T+ F ++I+ G TEA I + YY +V + ++P G PL N Sbjct: 4876 GADSCPAEDFKTLLARFGQKMRIINSYGVTEACIDTSYYEETDVTAIRSGTVPIGKPLPN 4935 Query: 1647 QQFYVLNQQMDYCPLEVSGELYIGGSGVANGYLNDPEKPSHSFIHHPEL--GYIYRTGDY 1704 YV++ ++ P+ V GEL IGG+GVA GYLN PE F+ +P +YRTGD Sbjct: 4936 MTMYVVDAHLNLQPVGVVGELCIGGAGVARGYLNRPELTEEKFVPNPFAPGERLYRTGDL 4995 Query: 1705 GVLHRDGCIEFLGRKDQQVKVGGYRIELGEVEAQLLRCGGVRHAVVLAAD--GEDKRLGA 1762 DG +EFLGR D QVK+ G RIELGE+E QL + G+ AVV+A + G++K L A Sbjct: 4996 AKWRADGNVEFLGRNDHQVKIRGVRIELGEIETQLRKLDGITEAVVVAREDRGQEKELCA 5055 Query: 1763 YLIPDSQSADQAAFINEVRARIAKVLPDYMIPHYFVVLEQFPLTANGKMDVQALLKLQPA 1822 Y++ AD E+RA + K LP MIP YFV L+ PLTANGK+D ++L PA Sbjct: 5056 YVV-----ADHKLDTAELRANLLKELPQAMIPAYFVTLDALPLTANGKVDRRSL----PA 5106 Query: 1823 GNK---QTSAYTAPRNDVEERIVNIFKELLEADQVGTLDNFFEMGINSVQIAMINNKLKQ 1879 + +T+ Y APR+ E R+ +++++L QVG LD+FF +G +S++ + + + Sbjct: 5107 PDVTMLRTTEYVAPRSVWEARLAQVWEQVLNVPQVGALDDFFALGGHSLRAMRVLSSMHN 5166 Query: 1880 EFQKEIPLLTLFEYANIHALAGYL 1903 E+Q +IPL LFE I LA ++ Sbjct: 5167 EYQVDIPLRILFEKPTIQELAAFI 5190 Score = 961 bits (2485), Expect = 0.0, Method: Compositional matrix adjust. Identities = 640/1946 (32%), Positives = 995/1946 (51%), Gaps = 110/1946 (5%) Query: 14 YWLETFSGEIPLLHLPADHSRPAFKTYRGSAEMFSIPKEQVLEIKQLAAEQEATLYMVLF 73 +W TF+GEIPLL+LP D+ RP+ +++ G + ++++LAAE TL+MVL Sbjct: 4344 FWTRTFAGEIPLLNLPHDYPRPSVQSFDGDTVALGTGHHLLEQLRKLAAETGTTLFMVLL 4403 Query: 74 AVWNILLAKLSDQEEIIVGVPTSGRNHSDIEHVIGMFVNTLPIKSRISAKLTFAEILHAM 133 A +++LL+K + QEEI+VG P +GR+H+D+E ++GMFVNTL +K+ + L+F L + Sbjct: 4404 AAYHVLLSKYAGQEEIVVGTPIAGRSHADVERIVGMFVNTLALKNTAAGSLSFRAFLEDV 4463 Query: 134 KANISNALEHQDYPFEDLVSQLQITRDFGRNPLFDVMFXXXXXXXXXXXXXXXXXXELQM 193 K N +A EHQDYPFE LV +LQ+ RD RNPLFD MF +L++ Sbjct: 4464 KQNALHAFEHQDYPFEHLVEKLQVRRDLSRNPLFDTMFSLGLAESAEGEVA-----DLKV 4518 Query: 194 KPYPYTTTTSRFDLTLDGEERAGELVFTLEYATDLFTRETVMRLIRYFRTILLEVLKHPA 253 PYP ++FDL+LD E+ L+ Y T LF +ETV RL ++ +L + P Sbjct: 4519 SPYPVNGHIAKFDLSLDAMEKQDGLLVQFSYCTKLFAKETVDRLAAHYVQLLQTITADPD 4578 Query: 254 QKTGLIHLPDNQETDRLLNRFNQTAGEYPEHLTVHQLFAARVKEHPHQAAVTFRNQSITY 313 + I + ET+ +L+ F T YP T +LF +V++ P++ AV F N+ +TY Sbjct: 4579 IELARISVLSKAETEHMLHSFLATKTAYPTDKTFQKLFEEQVEKTPNEIAVLFGNEQLTY 4638 Query: 314 DELNXXXXXXXXXXXXXGIGPDQIVALITTRSVDMXXXXXXXXXXXXXXXPIDPGLPANR 373 ELN G+ P+ V ++ RS+ M PIDP P R Sbjct: 4639 QELNAKANQLARVLRRKGVKPESTVGILVDRSLYMVIGMLAVLKAGGTFVPIDPDYPLER 4698 Query: 374 IAYMLDDAGVQVILT----NTSVENQGNRIVLDMRSLGLDHGAPLPVPPVHSSRNLAYCM 429 A+ML+D+ +++LT N+ V LD ++ + L V N+AY + Sbjct: 4699 QAFMLEDSEAKLLLTLQKMNSQVAFPYETFYLDTETVDQEETGNLE--HVAQPENVAYII 4756 Query: 430 YTSGTTGLPKGILVEHRSLLNFFSAISDVLSFGKGET-FLSLTTVSFDIFWLESILPLLA 488 YTSGTTG PKG+++EHRS N A D L + + +FD+ + LL Sbjct: 4757 YTSGTTGKPKGVVIEHRSYANVAFAWKDEYHLDSFPVRLLQMASFAFDVSTGDFARALLT 4816 Query: 489 GYQLVIADELQQKDVHALLALVKQAEISVMQTTPSRXX-XXXXXXXXXXXXXXXRYLLIG 547 G QLVI + D +L +++ EI++ + TP+ + L++G Sbjct: 4817 GGQLVICPNGVKMDPASLYETIRRHEITIFEATPALIMPLMHYVYENELDMSQMKLLILG 4876 Query: 548 GEPLPQALAEQARSILP----GGRIFNLYGPTETTIWSTAQEVT------AGPVNIGKPL 597 + P AE +++L RI N YG TE I ++ E T +G V IGKPL Sbjct: 4877 ADSCP---AEDFKTLLARFGQKMRIINSYGVTEACIDTSYYEETDVTAIRSGTVPIGKPL 4933 Query: 598 KNTQVYILNDELLLQPIGVPGILYIGGHGVVRGYQNNPELTAQRFIDNPYRPGEQIYCTG 657 N +Y+++ L LQP+GV G L IGG GV RGY N PELT ++F+ NP+ PGE++Y TG Sbjct: 4934 PNMTMYVVDAHLNLQPVGVVGELCIGGAGVARGYLNRPELTEEKFVPNPFAPGERLYRTG 4993 Query: 658 DIARWTEEGTIEYLGRADFQVKIRGYRIELAEIEQQLDTHPAIEKSVVRAQRDDQDEPML 717 D+A+W +G +E+LGR D QVKIRG RIEL EIE QL I ++VV A+ D E L Sbjct: 4994 DLAKWRADGNVEFLGRNDHQVKIRGVRIELGEIETQLRKLDGITEAVVVAREDRGQEKEL 5053 Query: 718 VAYYTAARTVSGAELREFLLKFLPAYMIPQHFMEIGKIPLMISGKLDVKALPPVTVTLVQ 777 AY A + AELR LLK LP MIP +F+ + +PL +GK+D ++LP VT+++ Sbjct: 5054 CAYVVADHKLDTAELRANLLKELPQAMIPAYFVTLDALPLTANGKVDRRSLPAPDVTMLR 5113 Query: 778 PGETRKPQDEVEEKLLEIWKKVLRIGDTGVQDGFFEMGGNSIQIMQLVYEINKCFPVSFQ 837 E P+ E +L ++W++VL + G D FF +GG+S++ M+++ ++ + V Sbjct: 5114 TTEYVAPRSVWEARLAQVWEQVLNVPQVGALDDFFALGGHSLRAMRVLSSMHNEYQVDIP 5173 Query: 838 FTHFIERQTIERIADFIKEAIQEERKEELPFIAADPANRHEPFPLTNVQMAYYLGRSSHF 897 E+ TI+ +A FI+E + + +P + +P+++ Q Y+ F Sbjct: 5174 LRILFEKPTIQELAAFIEETAKGN------VFSIEPVQKQAYYPVSSAQKRMYI--LDQF 5225 Query: 898 ELGGVSTH--SYLEMATELDIRRLNQCLNTLIQRHPALHTVYL---PDATQQILPEVPEY 952 E G+S + S + + +L+ R+ LI RH +L T + + Q I +VP Sbjct: 5226 EGVGISYNMPSTMLIEGKLERTRVEAAFQRLIARHESLRTSFAVVNGEPVQNIHEDVP-- 5283 Query: 953 TICEYDLSGYTEEAKNKRITKERDRMSHHI--FNPNVWPLFEIVAFRSSPEESLLCISFD 1010 + L+ Y+E + + R+ +S + F+ V PL + + + +L Sbjct: 5284 ----FALA-YSEVTEQ----EARELVSSLVQPFDLEVAPLIRVSLLKIGEDRYVLFTDMH 5334 Query: 1011 LLIMDAYSLEILQEEIMALYADRSLQLEELSITFRDYLVGYQQMKSGKWYLEDKEYWLQK 1070 I D S IL E + LY + L EL I ++D+ V Q+ + + + YWLQ Sbjct: 5335 HSISDGVSSGILLAEWVQLY--QGDVLPELRIQYKDFAVWQQEFSQSAAFHKQEAYWLQT 5392 Query: 1071 VEDFPLAPGLPLLTQPQHVKNPYFK-----RKSKHYSQQHWRQLKQISQNHNLTPSAVLC 1125 D +P+L P P + + + + L Q++Q T VL Sbjct: 5393 FAD-----DIPVLNLPTDFTRPSTQSFAGDQCTIGAGKALTEGLHQLAQATGTTLYMVLL 5447 Query: 1126 TVYAEVLANWSNQPQFGLNLTLFNRLPLHSDVDKLIGDFTSLLLLEVRMNPNDSFWEKAG 1185 Y +LA ++ Q + + R H+D++ ++G F + L + + +F E Sbjct: 5448 AAYNVLLAKYAGQEDIIVGTPITGR--SHADLEPIVGMFVNTLAMRNKPQREKTFSEFLQ 5505 Query: 1186 NIQRVLMEALAHRHFDGIDVMREISKRRALGNKALLPIVFTSALFDNGEDGGEAAENHGE 1245 +++ ++A H+ + +++ +++ R L L VFT F N E E Sbjct: 5506 EVKQNALDAYGHQDYPFEELVEKLAIARDLSRNPLFDTVFT---FQNST---EEVMTLPE 5559 Query: 1246 ASDGEQSTNGITQTSQVYLDNQVALIHGKMVINWDYISELFDPAVMDAMFAQYLSRIEAI 1305 + T+ Q ++ L +M I +Y + LF M+ F+++ I A Sbjct: 5560 CTLAPFMTDETGQHAKFDLTFSATEEREEMTIGVEYSTSLFTRETME-RFSRHFLTIAAS 5618 Query: 1306 LYSREEMGFPA----LPASDYTSIQAYNHTEEPIP-SKTLHGLFEEAVHQTPYAVAIEAD 1360 + + LP + +N T KTLH LFEE V +TP A+ Sbjct: 5619 IVQNPHIRLGEIDMLLPEEKQQILAGFNDTAVSYALDKTLHQLFEEQVDKTPDQAALLFS 5678 Query: 1361 NLSITYKELDDRADKVAGSLRSLGVSAGDRVGVIARKEIATFINILGILKSGAAYVPIDP 1420 S+TY EL++RA+++A LR+ GV V ++A + I ILGILK+G AYVP+DP Sbjct: 5679 EQSLTYSELNERANRLARVLRAKGVGPDRLVAIMAERSPEMVIGILGILKAGGAYVPVDP 5738 Query: 1421 EYPQERVDYIRNHSQCKLVLET------------------DYYEKNCRGQHPAELQRHNL 1462 YPQER+ Y+ S L+L D + G + L N Sbjct: 5739 GYPQERIQYLLEDSNAALLLSQAHLLPLLAQVSSELPECLDLNAELDAGLSGSNLPAVNQ 5798 Query: 1463 PESLAYVIYTSGSTGNPKGVMISHQAACNTVQDINQKFQVGAADRMLGISSLCFDLSVYD 1522 P LAYVIYTSG+TG PKGVMI HQ N +Q ++ G +D+ L + S FD V Sbjct: 5799 PTDLAYVIYTSGTTGKPKGVMIPHQGIVNCLQWRRDEYGFGPSDKALQVFSFAFDGFVAS 5858 Query: 1523 IFGAFAAGATLVLVKD--QKDIRQLADTLSAQKITIWNSVPAIMDRVGSEIRAQGIYQEN 1580 +F GAT VL ++ KD L ++A ++T + VP++ + Q Sbjct: 5859 LFAPLLGGATCVLPQEAAAKDPVALKKLMAATEVTHYYGVPSLFQAILDCSTTTDFNQ-- 5916 Query: 1581 LDLRLVLLSGDWIPLHLPETVKQLFPAAKLISCGGATEASIWSIYYPIDEVMPQWTSIPY 1640 LR V L G+ +P+ L + K+ PA ++ + G TE S+ + I + +I Sbjct: 5917 --LRCVTLGGEKLPVQLVQKTKEKHPAIEINNEYGPTENSVVTT---ISRSIEAGQAITI 5971 Query: 1641 GMPLANQQFYVLNQQMDYCPLEVSGELYIGGSGVANGYLNDPEKPSHSFIHHP--ELGYI 1698 G PLAN Q Y++++Q P+ V GEL IGG+G+A GYLN PE + F+ +P + Sbjct: 5972 GRPLANVQVYIVDEQHHLQPIGVVGELCIGGAGLARGYLNKPELTAEKFVANPFRPGERM 6031 Query: 1699 YRTGDYGVLHRDGCIEFLGRKDQQVKVGGYRIELGEVEAQLLRCGGVRHAVVLAADGEDK 1758 Y+TGD DG IE++GR D+QVKV GYRIE+GE+E+ +L G+ AVV+A D +D Sbjct: 6032 YKTGDLVKWRTDGTIEYIGRADEQVKVRGYRIEIGEIESAVLAYQGIDQAVVVARD-DDA 6090 Query: 1759 RLGAYLIPDSQSADQAAFINEVRARIAKVLPDYMIPHYFVVLEQFPLTANGKMDVQALLK 1818 G+YL +A A ++ +R+ +AK LP YMIP YFV L+Q PL+ANGK+D +AL K Sbjct: 6091 TAGSYLCAYFVAA-TAVSVSGLRSHLAKELPAYMIPSYFVELDQLPLSANGKVDRKALPK 6149 Query: 1819 LQPAGNKQTSAYTAPRNDVEERIVNIFKELLEADQVGTLDNFFEMGINSVQIAMINNKLK 1878 Q + + T Y APRN E+++ I++E+L + +G D FFE+G +S++ ++ K+ Sbjct: 6150 PQQS-DATTREYVAPRNATEQQLAAIWQEVLGVEPIGITDQFFELGGHSLKATLLIAKVY 6208 Query: 1879 QEFQKEIPLLTLFEYANIHALAGYLS 1904 + Q E+PL +F+Y I +A +++ Sbjct: 6209 EYMQIELPLNLIFQYPTIEKVADFIT 6234 Score = 939 bits (2428), Expect = 0.0, Method: Compositional matrix adjust. Identities = 625/1939 (32%), Positives = 997/1939 (51%), Gaps = 110/1939 (5%) Query: 14 YWLETFSGEIPLLHLPADHSRPAFKTYRGSAEMFSIPKEQVLEIKQLAAEQEATLYMVLF 73 YWL TF+GEIP+L+LP D+ RP+ K++ G +F ++ QLA E TLYMVL Sbjct: 2271 YWLNTFTGEIPVLNLPTDYPRPSVKSFAGDRFVFGSGTALPKQLHQLAQETGTTLYMVLL 2330 Query: 74 AVWNILLAKLSDQEEIIVGVPTSGRNHSDIEHVIGMFVNTLPIKSRISAKLTFAEILHAM 133 A +N+LL+K S QE+IIVG PT+GR+H++ E ++GMFVNTL +++ + TF + L + Sbjct: 2331 AAYNVLLSKYSRQEDIIVGAPTAGRSHAETESIVGMFVNTLALRNEPAGGKTFRDFLAEV 2390 Query: 134 KANISNALEHQDYPFEDLVSQLQITRDFGRNPLFDVMFXXXXXXXXXXXXXXXXXXELQM 193 K N A EHQDYP ++LV +L + RD RNPLFD +F +L + Sbjct: 2391 KINTLGAFEHQDYPLDELVDKLDMQRDLSRNPLFDTVFILQNMEQKPFEME-----QLTI 2445 Query: 194 KPYPYTTTTSRFDLTLDGEERAGELVFTLEYATDLFTRETVMRLIRYFRTILLEVLKHPA 253 PY ++FDL+L+ E E++F+L+Y+T LF+RET+ ++ +F IL V+ P Sbjct: 2446 TPYSAEVKQAKFDLSLEAYEENAEIIFSLDYSTKLFSRETIEKIATHFIQILRAVIAEPE 2505 Query: 254 QKTGLIHLPDNQETDRLLNRFNQTAGEYPEHLTVHQLFAARVKEHPHQAAVTFRNQSITY 313 I + E RLL FN ++P++ T+ LF + ++ P AV Q ++Y Sbjct: 2506 MPLSEITMLTEAEKQRLLVDFNGAHKDFPQNKTLQALFEEQAEKSPQATAVEISGQPLSY 2565 Query: 314 DELNXXXXXXXXXXXXXGIGPDQIVALITTRSVDMXXXXXXXXXXXXXXXPIDPGLPANR 373 ELN G+ PDQ V ++ RSV+M PIDP P R Sbjct: 2566 QELNERANQLAATLRERGVQPDQPVGIMANRSVEMVVGILAILKAGGAYVPIDPEYPEER 2625 Query: 374 IAYMLDDAGVQVILTNTSVENQ-GNRIVLDMRSLGLDHGAPLPV-----PPVHSSRNLAY 427 +AYML D +++LT + + G+ + + L LD + V P++++ +LAY Sbjct: 2626 VAYMLTDCQARLVLTQKHLGAKLGSSVTAE--CLYLDDESNYGVHRSNLQPINTASDLAY 2683 Query: 428 CMYTSGTTGLPKGILVEHRSLLNFFSAISDVLSFGKGETFLSLTTVSFDIFWLESILPLL 487 +YTSGTTG PKG++VEHR ++N G+ L + +FD F L P+L Sbjct: 2684 IIYTSGTTGKPKGVMVEHRGIVNNVLWKKAEYQMKVGDRSLLSLSFAFDAFVLSFFTPVL 2743 Query: 488 AGYQLVIADELQQKDVHALLALVKQAEISVMQTTPSRXXXXXXXXXXXXXXXXXRYLLIG 547 +G +V+A++ + KD +L L+ + ++M PS + + +G Sbjct: 2744 SGATVVLAEDEEAKDPVSLKKLIAASRCTLMTGVPS-LFQAILECSTPADIRPLQTVTLG 2802 Query: 548 GEPLPQALAEQARSILPGGRIFNLYGPTETTIWSTAQEVTAGP---VNIGKPLKNTQVYI 604 GE + L E+ + + P I N YGPTE+++ +T Q + AGP + IG+P+ NT +YI Sbjct: 2803 GEKITAQLVEKCKQLNPDLVIVNEYGPTESSVVATWQRL-AGPDAAITIGRPIANTSLYI 2861 Query: 605 LNDELLLQPIGVPGILYIGGHGVVRGYQNNPELTAQRFIDNPYRPGEQIYCTGDIARWTE 664 +N LQPIGV G + IGG G+ RGY N P LT ++F+ +P+ GE++Y TGD+ +W Sbjct: 2862 VNQYHQLQPIGVVGEICIGGRGLARGYWNKPALTEEKFVSHPFAAGERMYKTGDLGKWLP 2921 Query: 665 EGTIEYLGRADFQVKIRGYRIELAEIEQQLDTHPAIEKSVVRAQRDDQDEPMLVAYYTAA 724 +GTIEY+GR D QVK+RGYRIE+ EIE L + +VV D + L AY+TA Sbjct: 2922 DGTIEYIGRIDEQVKVRGYRIEIGEIESALLAAEKLTAAVVVVYEDQLGQSALAAYFTAD 2981 Query: 725 RTVSGAELREFLLKFLPAYMIPQHFMEIGKIPLMISGKLDVKALPPVTVTLVQPGETRKP 784 + +L L K LP+YMIP HF+++ ++PL +GK+D KALP V + P Sbjct: 2982 EQLDVTKLWSHLSKRLPSYMIPAHFVQLDQLPLTPNGKVDKKALPKPEGKPVTEAQYVAP 3041 Query: 785 QDEVEEKLLEIWKKVLRIGDTGVQDGFFEMGGNSIQIMQLVYEINKCFPVSFQFTHFIER 844 + VE KL EIW++VL + G+ D FF++GG+S++ M + ++++ + V + Sbjct: 3042 TNAVESKLAEIWERVLGVSGIGILDNFFQIGGHSLKAMAVAAQVHREYQVELPLKVLFAQ 3101 Query: 845 QTIERIADFIKEAIQEERKEELPFIAADPANRHEPFPLTNVQMAYYLGRSSHFELGGV-S 903 TI+ +A ++ + +E ++ +PA E +P+++ Q Y+ R + G V + Sbjct: 3102 PTIKALAQYVATSGKET------YVPIEPAPLQEYYPVSSAQKRMYVLR-QFADTGTVYN 3154 Query: 904 THSYLEMATELDIRRLNQCLNTLIQRHPALHTVYLPDATQQILPEVPEYTICEYDLSGYT 963 S L + +LD +R ++ L++RH +L T + + + V E+ + T Sbjct: 3155 MPSALYIEGDLDRKRFEAAIHGLVERHESLRTSF-HTVNGEPVQRVHEHVELNVQYAEVT 3213 Query: 964 EEAKNKRITKERDRMSHHIFNPNVWPLFEIVAFRSSPEESLLCISFDLLIMDAYSLEILQ 1023 E + F+ PL + F+ + + L + +I D S I+ Sbjct: 3214 EAQVEPTVES-----FVQAFDLTKAPLLRVGLFKLAAKRHLFLLDMHHIISDGVSAGIIM 3268 Query: 1024 EEIMALYADRSLQLEELSITFRDYLVGYQQMKSGKWYLEDKEYWLQKVEDFPLAPGLPLL 1083 EE LY R +L LS+ ++D+ V ++ Y E + YWL + +P+L Sbjct: 3269 EEFSKLY--RGEELPALSVHYKDFAVWQSELFQSDVYTEHENYWLNA-----FSGDIPVL 3321 Query: 1084 TQPQHVKNPYFKR-----KSKHYSQQHWRQLKQISQNHNLTPSAVLCTVYAEVLANWSNQ 1138 P P + S + L +++Q T VL Y +LA +S Q Sbjct: 3322 NLPADFSRPLTQSFEGDCVSFQADKALLDDLHKLAQESQSTLFMVLLAAYNVLLAKYSGQ 3381 Query: 1139 PQFGLNLTLFNRLPLHSDVDKLIGDFTSLLLLEVRMNPNDSFWEKAGNIQRVLMEALAHR 1198 + + R H+D++ ++G F + L L F +++ ++A AH+ Sbjct: 3382 EDIVVGTPIAGR--SHADIENVLGMFVNTLALRNYPVETKHFQAFLEEVKQNTLQAYAHQ 3439 Query: 1199 HFDGIDVMREISKRRALGNKALLPIVFTSALFDNGEDGGEAAENHG---EASDGEQSTNG 1255 + ++ ++ +R L L +F D +A E G EA + Sbjct: 3440 DYPFEALVEKLDIQRDLSRNPLFDTMFILQNLDQ-----KAYELDGLKLEAYPAQAGNAK 3494 Query: 1256 ITQTSQVYLDNQVALIHGKMVINWDYISELFDPAVMDAMFAQYLSRIEAILYSR----EE 1311 T + + D IH +V Y ++LF ++ M +L + ++ + E Sbjct: 3495 FDLTLEAHEDE--TGIHFALV----YSTKLFQRESIERMAGHFLQVLRQVVADQATALRE 3548 Query: 1312 MGFPALPASDYTSIQAYNHTEEPIPSK-TLHGLFEEAVHQTPYAVAIEADNLSITYKELD 1370 + + ++ +N+T P T+ LFE+ +TP A+ D +TY+EL+ Sbjct: 3549 ISLLSEEERRIVTVD-FNNTFAAYPRDLTIQELFEQQAAKTPEHAAVVMDGQMLTYRELN 3607 Query: 1371 DRADKVAGSLRSLGVSAGDRVGVIARKEIATFINILGILKSGAAYVPIDPEYPQERVDYI 1430 ++A+++A LR GV VG++A + + I+GILK+G AY+ +DPE+P ER+ Y+ Sbjct: 3608 EKANQLAHVLRQNGVGKESIVGLLADRSLEMITGIMGILKAGGAYLGLDPEHPSERLAYM 3667 Query: 1431 RNHSQCKLVLETDYY--------------EKNCRGQHPAELQRHNLPESLAYVIYTSGST 1476 K+VL + E++ R + N LAYV+YTSGST Sbjct: 3668 LEDGGVKVVLVQKHLLPLVGEGLMPIVLEEESLRPEDCGNPAIVNGASDLAYVMYTSGST 3727 Query: 1477 GNPKGVMISHQAACNTVQDINQKFQVGAADRMLGISSLCFDLSVYDIFGAFAAGATLVLV 1536 G PKGVM+ H+ V N QV +DRM+ ++ FD ++IFGA GA+L LV Sbjct: 3728 GKPKGVMVEHRNVTRLVMHTNY-VQVRESDRMIQTGAIGFDAMTFEIFGALLHGASLYLV 3786 Query: 1537 KDQK--DIRQLADTLSAQKI-TIWNSVPAIMDRVGSEIRAQGIYQENLD-LRLVLLSGDW 1592 D +L D L +I T+W + P + +++ + A D LR +++ G+ Sbjct: 3787 SKDVLLDAEKLGDFLRTNQITTMWLTSP-LFNQLSQDNPAM------FDSLRALIVGGEA 3839 Query: 1593 I-PLHLPETVKQLFPAAKLISCGGATEASIWSIYYPIDEVMPQWTSIPYGMPLANQQFYV 1651 + P H+ VK P ++ + G TE + +S Y I++ + IP G P+AN Y+ Sbjct: 3840 LSPKHI-NRVKSALPDLEIWNGYGPTENTTFSTCYLIEQHFEE--QIPIGKPIANSTAYI 3896 Query: 1652 LNQQMDYCPLEVSGELYIGGSGVANGYLNDPEKPSHSFIHHPEL--GYIYRTGDYGVLHR 1709 ++ P+ V GEL +GG GVA GY+N PE + F+ +P +YRTGD Sbjct: 3897 VDGNNQPQPIGVPGELCVGGDGVARGYVNKPELTAEKFVPNPFAPGETMYRTGDLARWLP 3956 Query: 1710 DGCIEFLGRKDQQVKVGGYRIELGEVEAQLLRCGGVRHAVVLA---ADGEDKRLGAYLIP 1766 DG IE+LGR DQQVK+ GYRIELGE+E L + V+ AVV A+G+ K L AY +P Sbjct: 3957 DGTIEYLGRIDQQVKIRGYRIELGEIETVLSQQAQVKEAVVAVIEEANGQ-KALCAYFVP 4015 Query: 1767 DSQSADQAAFINEVRARIAKVLPDYMIPHYFVVLEQFPLTANGKMDVQALLKLQPAGNKQ 1826 + Q+ D A E+R ++K LP YM+P Y+V +E+ PLTANGK+D +AL QP+G + Sbjct: 4016 E-QAVDAA----ELREAMSKQLPGYMVPAYYVQMEKLPLTANGKVDRRAL--PQPSGERT 4068 Query: 1827 T-SAYTAPRNDVEERIVNIFKELLEADQVGTLDNFFEMGINSVQIAMINNKLKQEFQKEI 1885 T SA+ A +ND E ++ I++E+L +G DNFFE+G +S++ + ++ + FQ E+ Sbjct: 4069 TGSAFVAAQNDTEAKLQQIWQEVLGIPAIGIHDNFFEIGGHSLKAMNVITQVHKTFQVEL 4128 Query: 1886 PLLTLFEYANIHALAGYLS 1904 PL LF IH LA +++ Sbjct: 4129 PLKALFATPTIHELAAHIA 4147 Score = 792 bits (2046), Expect = 0.0, Method: Compositional matrix adjust. Identities = 572/1964 (29%), Positives = 956/1964 (48%), Gaps = 137/1964 (6%) Query: 14 YWLETFSGEIPLLHLPADHSRPAFKTYRGSAEMFSIPKEQVLEIKQLAAEQEATLYMVLF 73 YW +G P Y MF+I E+ ++ Q+A + +AT+ V Sbjct: 197 YWQNYLAGYDHQAAFPKKKLGTEASRYEHVEAMFTIAPEKTQQLIQIANQNQATMSSVFQ 256 Query: 74 AVWNILLAKLSDQEEIIVGVPTSGR--NHSDIEHVIGMFVNTLPIKSRISAKLTFAEILH 131 A+W IL + + ++++ G SGR IE ++G+F+NT+P + + + + TF+E+L Sbjct: 257 ALWGILASTYKNADDVVFGSVVSGRPPQIQGIESMVGLFINTIPTRVQTNKQQTFSELLQ 316 Query: 132 AMKANISNALEHQDYPFEDLVSQLQITRDFGRNPLFDVMFXXXXXXXXXXXXXXXXXXEL 191 ++ AL Y F L ++Q T + + ++ + Sbjct: 317 TVQ---KQALASATYDFAPLY-EIQSTTVLKQELIDHLVTFENYPDHSMKHLEESLGFQF 372 Query: 192 QMKPYPYTTTTSRFDL-TLDGEERAGELVFTLEYATDLFTRETVMRLIRYFRTILLEVLK 250 ++ T+ +DL + + EL L Y ++ V R+ + RT++ +V+ Sbjct: 373 TVESGDEQTS---YDLNVVVALAPSNELYVKLSYNAAVYESSFVNRIEGHLRTVIDQVIG 429 Query: 251 HPAQKTGLIHLPDNQETDRLLNRFNQTAGEYPEHLTVHQLFAARVKEHPHQAAVTFRNQS 310 +P I + +E +LL +N TA EYP T+ +L A + P +AAV + Sbjct: 430 NPHVHLHEIGIITEEEKQQLLVAYNDTAAEYPRDKTIFELIAEQASRTPAKAAVVCGEDT 489 Query: 311 ITYDELNXXXXXXXXXXXXXGIGPDQIVALITTRSVDMXXXXXXXXXXXXXXXPIDPGLP 370 +TY EL GI IV+++ S+++ PIDP P Sbjct: 490 LTYQELMERSAQLANALREKGIASGSIVSIMAEHSLELIVAIMAVLRSGAAYLPIDPEYP 549 Query: 371 ANRIAYMLDDAGVQVILTNT----SVENQGNRIVLDMRSLGLDHGAPLPVPPVHSSRNLA 426 +RI Y+LDD+ ++LT + ++ G+ + LD RSL G P +LA Sbjct: 550 QDRIQYLLDDSQTTLLLTQSHLQPNIRFAGSVLYLDDRSLY--EGGSTSFAPESKPDDLA 607 Query: 427 YCMYTSGTTGLPKGILVEHRSLLNFFSAISDVLSFGKGETFLSLTTVSFDIFWLESILPL 486 Y +YTSG+TG PKG ++ H+ L+N+ + V G+ F +++SFD+ PL Sbjct: 608 YMIYTSGSTGNPKGAMITHQGLVNYIWWANKVYVQGEAVDFPLYSSISFDLTVTSIFTPL 667 Query: 487 LAGYQLVI---ADELQQKDVHALLALVKQAEISVMQTTPSRXXXXXXXXXXXXXXXXXRY 543 L+G + + AD++Q +L ++K ++ +++ TP+ R Sbjct: 668 LSGNTIHVYRGADKVQ-----VILDIIKDNKVGIIKLTPTHLKLIEHIDGKASSI---RR 719 Query: 544 LLIGGEPLPQALAEQARSILPGG-RIFNLYGPTETTIWST-----AQEVTAGPVNIGKPL 597 ++GGE LP LA+Q +IFN YGPTET + Q T V IG P Sbjct: 720 FIVGGENLPTKLAKQIYDHFGENVQIFNEYGPTETVVGCMIYLYDPQTTTQESVPIGVPA 779 Query: 598 KNTQVYILNDELLLQPIGVPGILYIGGHGVVRGYQNNPELTAQRFIDNPYRPGEQIYCTG 657 N Q+Y+L+ + P+G G +YI G GV +GY N PELT ++FIDNP+RPG ++Y TG Sbjct: 780 DNVQLYLLDASMQPVPVGSLGEMYIAGDGVAKGYFNRPELTKEKFIDNPFRPGTKMYRTG 839 Query: 658 DIARWTEEGTIEYLGRADFQVKIRGYRIELAEIEQQLDTHPAIEKSVVRAQRDDQDEPML 717 D+A+W +G +EY GR D+QVKIRG+RIE+ EIE +L H A++++VV ++D+ + +L Sbjct: 840 DLAKWLPDGNMEYAGRMDYQVKIRGHRIEMGEIETRLTQHEAVKEAVVIVEKDESGQNVL 899 Query: 718 VAYYTAARTVSGAELREFLLKFLPAYMIPQHFMEIGKIPLMISGKLDVKALPPVTVTLVQ 777 AY + R ++ AELREFL + LP+YMIP F+ + +IPL +GK++ K LP +V Sbjct: 900 YAYLVSERELTVAELREFLGRTLPSYMIPSFFIRLAEIPLTANGKVERKKLPKPAGAVVT 959 Query: 778 PGETRKPQDEVEEKLLEIWKKVLRIGDTGVQDGFFEMGGNSIQIMQLVYEINKCFPVSFQ 837 PQ+E+E KL EIW++VL I G+ D FF++GG+S++ M +V++++K V Sbjct: 960 GTAYAAPQNEIEAKLAEIWQQVLGISQVGIHDDFFDLGGHSLKAMTVVFQVSKALEVELP 1019 Query: 838 FTHFIERQTIERIADFIKEAIQEERKEELPFIAADPANRHEPFPLTNVQMAYYLGRSSHF 897 E T+ +A F+ R E+ + A P E +P+++ Q Y+ + F Sbjct: 1020 VKALFEHPTVAELARFLS------RSEKTEYTAIQPVAAQEFYPVSSAQKRMYILQ--QF 1071 Query: 898 ELGGVSTH--SYLEMATELDIRRLNQCLNTLIQRHPALHTVYLPDATQQILPEVPEYTIC 955 E G+S + + + +LD R + L +RH AL T + + + E + Sbjct: 1072 EGNGISYNISGAILLEGKLDYARFASAVQQLAERHEALRTSFHRIDGEPVQKVHEEVEVP 1131 Query: 956 EYDLSGYTEEAKNKRITKERDRMSHHIFNPNVWPLFEIVAFRSSPEESLLCISFDLLIMD 1015 + L ++A ++I +E R F+ V PL + + L + +I D Sbjct: 1132 LFMLEAPEDQA--EKIMREFVRP----FDLGVAPLMRTGLLKLGKDRHLFLLDMHHIISD 1185 Query: 1016 AYSLEILQEEIMALYADRSLQLEELSITFRDYLVGYQQMKSGKWYLEDKEYWLQKVEDFP 1075 S +IL E LY LQ LS+ ++D+ ++ + Y + +++WL D Sbjct: 1186 GVSSQILLREFAELYQGADLQ--PLSLQYKDFAAWQNELFQTEAYKKQEQHWLNTFAD-- 1241 Query: 1076 LAPGLPLLTQPQHVKNPYFKRKSKHY-----SQQHWRQLKQISQNHNLTPSAVLCTVYAE 1130 +PLL P P + + ++ +L+Q++ T +L Y Sbjct: 1242 ---EIPLLNLPTDYPRPSVQSFAGDLVLFAAGKELLERLQQVASETGTTLYMILLAAYNV 1298 Query: 1131 VLANWSNQPQFGLNLTLFNRLPLHSDVDKLIGDFTSLLLLEVRMNPNDSFWEKAGNIQRV 1190 +L+ ++ Q + + R H+DV+ ++G F + L L + + +F + +++ Sbjct: 1299 LLSKYTGQEDIIVGTPVAGR--SHADVENIMGIFVNTLALRNQPASSKTFAQFLQEVKQN 1356 Query: 1191 LMEALAHRHFDGIDVMREISKRRALGNKALLPIVFTSALFDNGEDGGEAAENHGEASDGE 1250 + A H+ + +++ +++ +R + L +F+ +N N + E Sbjct: 1357 ALAAYDHQDYPFEELVEKLAIQRDISRNPLFDTLFS---LENA--------NQQSLAIAE 1405 Query: 1251 QSTNG---ITQTSQVYLDNQVALIHGKMVINWDYISELFDPAVMDAMFAQYLSRIEAILY 1307 + + + S+ L + + + ++LF ++ M YL E + + Sbjct: 1406 LTASPYELFNKISKFDLALNASESPADIQFQLTFATKLFKKETVERMARHYL---EILRW 1462 Query: 1308 SREEMGFPALPASDYTSIQAYNHTE-------------EPIPSKTLHGLFEEAVHQTPYA 1354 E+ P + I E E + LH L EE +TP Sbjct: 1463 ISEQ------PTASLADIDMMTEAEKRTLLLNVNDTFVERTAATALHQLVEEQAARTPDE 1516 Query: 1355 VAIEADNLSITYKELDDRADKVAGSLRSLGVSAGDRVGVIARKEIATFINILGILKSGAA 1414 VA+ + ++TY+EL+ RA+++A LRS G +G++ + + +L +LK+G A Sbjct: 1517 VAVVYEEYALTYRELNARANQLARLLRSHGTGPDTLIGIMVDRSPGMVVGMLAVLKAGGA 1576 Query: 1415 YVPIDPEYPQERVDYIRNHSQCKLVLETDYYEKNCRGQHP------------AELQRHNL 1462 Y PIDP YP ER+ Y+ + SQ ++L + ++ Q A+ N+ Sbjct: 1577 YTPIDPSYPPERIQYMLSDSQAPILLTQRHLQELAAYQGEIIDVDEEAIYTGADTNLDNV 1636 Query: 1463 P--ESLAYVIYTSGSTGNPKGVMISHQAACNTVQDINQKFQVGAADRMLGISSLCFDLSV 1520 + LAYVIYTSGSTGNPKGVMISHQA CN + + + F + D +L + FD SV Sbjct: 1637 AGKDDLAYVIYTSGSTGNPKGVMISHQAICNHMLWMRETFPLTTEDAVLQKTPFSFDASV 1696 Query: 1521 YDIFGAFAAGATLVLVK--DQKDIRQLADTLSAQKITIWNSVPAIMDRVGSEIRAQGIYQ 1578 ++ + G LVL K +DI + + +KIT VP+++D V ++ + Sbjct: 1697 WEFYLPLITGGQLVLAKPDGHRDIAYMTRLIRDEKITTLQMVPSLLDLVMTDPG----WS 1752 Query: 1579 ENLDLRLVLLSGDWIPLHLPETVKQLFPA--AKLISCGGATEASIWSIYYPIDEVMPQWT 1636 L+ V G+ + P V + + A+LI+ G TE +I + Y+P +++ Sbjct: 1753 ACTSLQRVFCGGEALT---PALVSRFYETQQAQLINLYGPTETTIDATYWPCPR-QQEYS 1808 Query: 1637 SIPYGMPLANQQFYVLNQQMDYCPLEVSGELYIGGSGVANGYLNDPEKPSHSFIHHP--E 1694 +IP G P+ N + YV+N P+ V+GEL I G G+A GY E SF+ +P Sbjct: 1809 AIPIGKPIDNVRLYVVNASNQLQPVGVAGELCIAGDGLARGYWQREELTKASFVDNPFEP 1868 Query: 1695 LGYIYRTGDYGVLHRDGCIEFLGRKDQQVKVGGYRIELGEVEAQLLRCGGVRHAVVLA-A 1753 G +YRTGD DG IE+LGR D QVK+ G+RIELGE+EA LL+ V+ VV+A Sbjct: 1869 GGTMYRTGDMVRYLPDGHIEYLGRIDHQVKIRGHRIELGEIEATLLQHEAVKAVVVMARQ 1928 Query: 1754 DGEDKR-LGAYLIPDSQSADQAAFINEVRARIAKVLPDYMIPHYFVVLEQFPLTANGKMD 1812 DG+ + L AY++ A+Q E+R ++ LP YM+P FV LEQ PL+ANGK+D Sbjct: 1929 DGKGQNSLYAYVV-----AEQDIQTAELRTYLSATLPAYMVPSAFVFLEQLPLSANGKVD 1983 Query: 1813 VQALLKLQPAG-NKQTSAYTAPRNDVEERIVNIFKELLEADQVGTLDNFFEMGINSVQIA 1871 +AL QP + Y APRN+ E ++ I++ +L + +G D+FFE+G +S++ Sbjct: 1984 RKAL--PQPEDAAASAAVYVAPRNEWEAKLAAIWESVLGVEPIGVHDHFFELGGHSLKAM 2041 Query: 1872 MINNKLKQEFQKEIPLLTLFEYANIHALAGYLSGNDQNEPDDVP 1915 + + L++ FQ ++PL LFE I LA ++ + +P Sbjct: 2042 HVISLLQRSFQVDVPLKVLFESPTIAGLAPLVAAARKGTYTAIP 2085 Score = 596 bits (1537), Expect = e-168, Method: Compositional matrix adjust. Identities = 342/906 (37%), Positives = 507/906 (55%), Gaps = 21/906 (2%) Query: 14 YWLETFSGEIPLLHLPADHSRPAFKTYRGSAEMFSIPKEQVLEIKQLAAEQEATLYMVLF 73 YWL+TF+ +IP+L+LP D +RP+ +++ G K + QLA TLYMVL Sbjct: 5388 YWLQTFADDIPVLNLPTDFTRPSTQSFAGDQCTIGAGKALTEGLHQLAQATGTTLYMVLL 5447 Query: 74 AVWNILLAKLSDQEEIIVGVPTSGRNHSDIEHVIGMFVNTLPIKSRISAKLTFAEILHAM 133 A +N+LLAK + QE+IIVG P +GR+H+D+E ++GMFVNTL ++++ + TF+E L + Sbjct: 5448 AAYNVLLAKYAGQEDIIVGTPITGRSHADLEPIVGMFVNTLAMRNKPQREKTFSEFLQEV 5507 Query: 134 KANISNALEHQDYPFEDLVSQLQITRDFGRNPLFDVMFXXXXXXXXXXXXXXXXXXELQM 193 K N +A HQDYPFE+LV +L I RD RNPLFD +F E + Sbjct: 5508 KQNALDAYGHQDYPFEELVEKLAIARDLSRNPLFDTVFTFQNSTEEVMTLP-----ECTL 5562 Query: 194 KPYPYTTTT--SRFDLTLDGEERAGELVFTLEYATDLFTRETVMRLIRYFRTILLEVLKH 251 P+ T ++FDLT E E+ +EY+T LFTRET+ R R+F TI ++++ Sbjct: 5563 APFMTDETGQHAKFDLTFSATEEREEMTIGVEYSTSLFTRETMERFSRHFLTIAASIVQN 5622 Query: 252 PAQKTGLIHLPDNQETDRLLNRFNQTAGEYPEHLTVHQLFAARVKEHPHQAAVTFRNQSI 311 P + G I + +E ++L FN TA Y T+HQLF +V + P QAA+ F QS+ Sbjct: 5623 PHIRLGEIDMLLPEEKQQILAGFNDTAVSYALDKTLHQLFEEQVDKTPDQAALLFSEQSL 5682 Query: 312 TYDELNXXXXXXXXXXXXXGIGPDQIVALITTRSVDMXXXXXXXXXXXXXXXPIDPGLPA 371 TY ELN G+GPD++VA++ RS +M P+DPG P Sbjct: 5683 TYSELNERANRLARVLRAKGVGPDRLVAIMAERSPEMVIGILGILKAGGAYVPVDPGYPQ 5742 Query: 372 NRIAYMLDDAGVQVILTNTSVENQGNRI------VLDMRSLGLDHG-APLPVPPVHSSRN 424 RI Y+L+D+ ++L+ + ++ LD+ + LD G + +P V+ + Sbjct: 5743 ERIQYLLEDSNAALLLSQAHLLPLLAQVSSELPECLDLNA-ELDAGLSGSNLPAVNQPTD 5801 Query: 425 LAYCMYTSGTTGLPKGILVEHRSLLNFFSAISDVLSFGKGETFLSLTTVSFDIFWLESIL 484 LAY +YTSGTTG PKG+++ H+ ++N D FG + L + + +FD F Sbjct: 5802 LAYVIYTSGTTGKPKGVMIPHQGIVNCLQWRRDEYGFGPSDKALQVFSFAFDGFVASLFA 5861 Query: 485 PLLAGYQLVIADELQQKDVHALLALVKQAEISVMQTTPSRXXXXXXXXXXXXXXXXXRYL 544 PLL G V+ E KD AL L+ E++ PS R + Sbjct: 5862 PLLGGATCVLPQEAAAKDPVALKKLMAATEVTHYYGVPS-LFQAILDCSTTTDFNQLRCV 5920 Query: 545 LIGGEPLPQALAEQARSILPGGRIFNLYGPTETTIWST-AQEVTAG-PVNIGKPLKNTQV 602 +GGE LP L ++ + P I N YGPTE ++ +T ++ + AG + IG+PL N QV Sbjct: 5921 TLGGEKLPVQLVQKTKEKHPAIEINNEYGPTENSVVTTISRSIEAGQAITIGRPLANVQV 5980 Query: 603 YILNDELLLQPIGVPGILYIGGHGVVRGYQNNPELTAQRFIDNPYRPGEQIYCTGDIARW 662 YI++++ LQPIGV G L IGG G+ RGY N PELTA++F+ NP+RPGE++Y TGD+ +W Sbjct: 5981 YIVDEQHHLQPIGVVGELCIGGAGLARGYLNKPELTAEKFVANPFRPGERMYKTGDLVKW 6040 Query: 663 TEEGTIEYLGRADFQVKIRGYRIELAEIEQQLDTHPAIEKSVVRAQRDDQDE-PMLVAYY 721 +GTIEY+GRAD QVK+RGYRIE+ EIE + + I+++VV A+ DD L AY+ Sbjct: 6041 RTDGTIEYIGRADEQVKVRGYRIEIGEIESAVLAYQGIDQAVVVARDDDATAGSYLCAYF 6100 Query: 722 TAARTVSGAELREFLLKFLPAYMIPQHFMEIGKIPLMISGKLDVKALPPVTVTLVQPGET 781 AA VS + LR L K LPAYMIP +F+E+ ++PL +GK+D KALP + E Sbjct: 6101 VAATAVSVSGLRSHLAKELPAYMIPSYFVELDQLPLSANGKVDRKALPKPQQSDATTREY 6160 Query: 782 RKPQDEVEEKLLEIWKKVLRIGDTGVQDGFFEMGGNSIQIMQLVYEINKCFPVSFQFTHF 841 P++ E++L IW++VL + G+ D FFE+GG+S++ L+ ++ + + Sbjct: 6161 VAPRNATEQQLAAIWQEVLGVEPIGITDQFFELGGHSLKATLLIAKVYEYMQIELPLNLI 6220 Query: 842 IERQTIERIADFIKEAIQEERKEELPFIAADPANRHEPFPLTNVQMAYYLGRSSHFELGG 901 + TIE++ADFI E R + + A F Q YY ++ E+ G Sbjct: 6221 FQYPTIEKVADFITHKRFESRYGTAILLNQETARNVFCFTPIGAQSVYYQKLAA--EIQG 6278 Query: 902 VSTHSY 907 VS +S+ Sbjct: 6279 VSLYSF 6284 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.137 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 2,771,448,658 Number of extensions: 116664031 Number of successful extensions: 326414 Number of sequences better than 1.0e-05: 2617 Number of HSP's gapped: 307383 Number of HSP's successfully gapped: 5987 Length of query: 1943 Length of database: 757,237,578 Length adjustment: 141 Effective length of query: 1802 Effective length of database: 374,408,619 Effective search space: 674684331438 Effective search space used: 674684331438 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)