BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0022.p (2331 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value sp|O30409|TYCC_BREPA Tyrocidine synthetase III [Includes: ATP-de... 639 0.0 ref|ZP_00110897.1| COG3319: Thioesterase domains of type I polyk... 630 e-178 gb|AAO23333.1| NcpA [Nostoc sp. ATCC 53789] 629 e-178 ref|ZP_00177151.1| hypothetical protein Cwat285401 [Crocosphaera... 619 e-175 ref|ZP_00111185.1| COG3319: Thioesterase domains of type I polyk... 618 e-175 >sp|O30409|TYCC_BREPA Tyrocidine synthetase III [Includes: ATP-dependent asparagine adenylase (AsnA) (Asparagine activase); ATP-dependent glutamine adenylase (GlnA) (Glutamine activase); ATP-dependent tyrosine adenylase (TyrA) (Tyrosine activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase)] pir||T31076 tyrocidine synthetase 3 - Brevibacillus brevis gb|AAC45930.1| tyrocidine synthetase 3 [Brevibacillus brevis] Length = 6486 Score = 639 bits (1647), Expect = 0.0, Method: Compositional matrix adjust. Identities = 394/1156 (34%), Positives = 608/1156 (52%), Gaps = 72/1156 (6%) Query: 1170 EIEQQIARIWGNLFQMPNIDIQDNFYELGGTSIMGIKIANRINEQYRVTMTIQDVFTHLT 1229 E E ++A IW ++ + I + D+F+ELGG S+ + + + + ++V + ++ +F T Sbjct: 2006 EWEAKLAAIWESVLGVEPIGVHDHFFELGGHSLKAMHVISLLQRSFQVDVPLKVLFESPT 2065 Query: 1230 VASLGKLVEQ-KLGTKTEAGAVNKQEVEYAKTSMPLSHAQRRIWFLQKMNPDLVAYNLPF 1288 +A L LV + GT T V KQE P+S AQ+R++ LQ+M ++YN+P Sbjct: 2066 IAGLAPLVAAARKGTYTAIPPVEKQEY------YPVSAAQKRMFILQQMEGAGISYNMPG 2119 Query: 1289 IRYFDMAIDLELLQQAASFLAGRHLLMRTKYVLKDGNPVQEVLPAYVPAVQSIDAAGQSD 1348 Y D +D E LQQA L RH +RT + G VQ V A+ S A +++ Sbjct: 2120 FMYLDGKLDTERLQQALKSLVQRHESLRTSFHSVQGETVQRVHDDVDLAI-SFGEATEAE 2178 Query: 1349 PELFVKMNIHQQKMKPFNLEMPPY-RIYLYTISDERACLYINFHHILTDGWSIDIYYREL 1407 I +Q ++PF+L P R L ++ ER ++ HHI+ DG SI + E Sbjct: 2179 TR-----QIAEQFIQPFDLGTAPLLRAGLIKLAPERHLFMLDLHHIVVDGVSIGLLIEEF 2233 Query: 1408 FSLYQAFLHQQPPRLPEVKEDYFDWILEQKAWEESEAFVEHEQFWLKELAKPLPVLSLPS 1467 LY LP ++ Y D+ Q+ W ++E F E E +WL +PVL+LP+ Sbjct: 2234 AQLYHG------EELPALRIQYKDFAKWQQDWFQTEEFAEQEAYWLNTFTGEIPVLNLPT 2287 Query: 1468 DHKAPAVQTYRGSFHKFTISGELYRKLKAHLETQQITANNFLLSAYFLLLHNLSQEQDII 1527 D+ P+V+++ G F L ++L + T LL+AY +LL S+++DII Sbjct: 2288 DYPRPSVKSFAGDRFVFGSGTALPKQLHQLAQETGTTLYMVLLAAYNVLLSKYSRQEDII 2347 Query: 1528 IGVPASGRNEQKWESVAGIFINTLCIRIHFQGITTFMELQDAVKHKVWSAMDKAQYPFDL 1587 +G P +GR+ + ES+ G+F+NTL +R G TF + VK A + YP D Sbjct: 2348 VGAPTAGRSHAETESIVGMFVNTLALRNEPAGGKTFRDFLAEVKINTLGAFEHQDYPLDE 2407 Query: 1588 LVEKVNPDRDLSRNPIYNVLFQFYD----KLYLENEGISP---------FELSCLAQETN 1634 LV+K++ RDLSRNP+++ +F + +E I+P F+LS A E N Sbjct: 2408 LVDKLDMQRDLSRNPLFDTVFILQNMEQKPFEMEQLTITPYSAEVKQAKFDLSLEAYEEN 2467 Query: 1635 QQIEISFEYNSDMYTDSTISRFAGYFLNIIGQVVDKPXXXXXXXXXXXXXXXXXXXSRFQ 1694 +I S +Y++ +++ TI + A +F+ I+ V+ +P F Sbjct: 2468 AEIIFSLDYSTKLFSRETIEKIATHFIQILRAVIAEPEMPLSEITMLTEAEKQRLLVDFN 2527 Query: 1695 GEQADLEDGQTIHGRFEAQVQKNPHAIALVYEEQQMTFQEVNGKANQLAWMLTGSGVQRN 1754 G D +T+ FE Q +K+P A A+ Q +++QE+N +ANQLA L GVQ + Sbjct: 2528 GAHKDFPQNKTLQALFEEQAEKSPQATAVEISGQPLSYQELNERANQLAATLRERGVQPD 2587 Query: 1755 TPVGIFVDRSFSSVIGILAILKAGGAYVPLDPGYPEDRIAYILAHSGAKWLLTENRYLQS 1814 PVGI +RS V+GILAILKAGGAYVP+DP YPE+R+AY+L A+ +LT+ Sbjct: 2588 QPVGIMANRSVEMVVGILAILKAGGAYVPIDPEYPEERVAYMLTDCQARLVLTQKHLGAK 2647 Query: 1815 VAAFAHEEGIQIINLSPVKEQSAVSQMYLADYEDE-LSRENPRTGGHGPDRMYIMYTSGS 1873 + + E +YL D + + R N + D YI+YTSG+ Sbjct: 2648 LGSSVTAEC-----------------LYLDDESNYGVHRSNLQPINTASDLAYIIYTSGT 2690 Query: 1874 TGKPKGVLVTHSNVLNFVTWSIGELQLQPKDALLLVTSISFDISVFEIFAALLSGSRLCI 1933 TGKPKGV+V H ++N V W E Q++ D LL S +FD V F +LSG+ + + Sbjct: 2691 TGKPKGVMVEHRGIVNNVLWKKAEYQMKVGDRSLLSLSFAFDAFVLSFFTPVLSGATVVL 2750 Query: 1934 ASMEHLKDTECLLAYMEAQHITIWHSVPSLMVQLMTLLRHHPGRYRHSPVLQQLRHLMLG 1993 A E KD L + A T+ VPSL ++ P R L+ + LG Sbjct: 2751 AEDEEAKDPVSLKKLIAASRCTLMTGVPSLFQAILEC--STPADIR------PLQTVTLG 2802 Query: 1994 GEAWSTSLAASLRETFPQAEIRNMYGPTEATIWVSSYK--PGPEIDESHPVMLIGRPIAN 2051 GE + L ++ P I N YGPTE+++ V++++ GP+ + IGRPIAN Sbjct: 2803 GEKITAQLVEKCKQLNPDLVIVNEYGPTESSV-VATWQRLAGPD-----AAITIGRPIAN 2856 Query: 2052 NRLIILDQYGNVCPPGVAGEIYIAGNNVTQGYYNDEEKTRMAFI--PQSNGQIFYKTGDS 2109 L I++QY + P GV GEI I G + +GY+N T F+ P + G+ YKTGD Sbjct: 2857 TSLYIVNQYHQLQPIGVVGEICIGGRGLARGYWNKPALTEEKFVSHPFAAGERMYKTGDL 2916 Query: 2110 GRYLPEGNVEFTGRRDQLVKVRGYRIELGEIEQALKELTSLQQIAVTAVKD--GETSKIV 2167 G++LP+G +E+ GR D+ VKVRGYRIE+GEIE AL L V +D G+ S + Sbjct: 2917 GKWLPDGTIEYIGRIDEQVKVRGYRIEIGEIESALLAAEKLTAAVVVVYEDQLGQ-SALA 2975 Query: 2168 CLYTGDQPVPQNQLKDAVRKRLPEYMIPAQFFHVERFLLTPNGKMDWRSMEKFVRETPGS 2227 +T D+ + +L + KRLP YMIPA F +++ LTPNGK+D +++ K + Sbjct: 2976 AYFTADEQLDVTKLWSHLSKRLPSYMIPAHFVQLDQLPLTPNGKVDKKALPKPEGKPVTE 3035 Query: 2228 IEAAGIRNEVDKKLSEIWKKLLGIPAVGIQENFFDIGGNSLLVVQMQGMIQQEFFQDIPM 2287 + N V+ KL+EIW+++LG+ +GI +NFF IGG+SL + + + +E+ ++P+ Sbjct: 3036 AQYVAPTNAVESKLAEIWERVLGVSGIGILDNFFQIGGHSLKAMAVAAQVHREYQVELPL 3095 Query: 2288 MDLFKYTSIEKISDYL 2303 LF +I+ ++ Y+ Sbjct: 3096 KVLFAQPTIKALAQYV 3111 Score = 599 bits (1545), Expect = e-169, Method: Compositional matrix adjust. Identities = 383/1158 (33%), Positives = 596/1158 (51%), Gaps = 77/1158 (6%) Query: 1171 IEQQIARIWGNLFQMPNIDIQDNFYELGGTSIMGIKIANRINEQYRVTMTIQDVFTHLTV 1230 +E ++A IW + + I I DNF+++GG S+ + +A +++ +Y+V + ++ +F T+ Sbjct: 3045 VESKLAEIWERVLGVSGIGILDNFFQIGGHSLKAMAVAAQVHREYQVELPLKVLFAQPTI 3104 Query: 1231 ASLGKLVEQKLGTKTEAGAVNKQEVEYAKTSMPLSHAQRRIWFLQKMNPDLVAYNLPFIR 1290 +L + V G +T EY P+S AQ+R++ L++ YN+P Sbjct: 3105 KALAQYVATS-GKETYVPIEPAPLQEY----YPVSSAQKRMYVLRQFADTGTVYNMPSAL 3159 Query: 1291 YFDMAIDLELLQQAASFLAGRHLLMRTKYVLKDGNPVQEVLPAYVPAVQSIDAA-GQSDP 1349 Y + +D + + A L RH +RT + +G PVQ V VQ + Q +P Sbjct: 3160 YIEGDLDRKRFEAAIHGLVERHESLRTSFHTVNGEPVQRVHEHVELNVQYAEVTEAQVEP 3219 Query: 1350 ELFVKMNIHQQKMKPFNL-EMPPYRIYLYTISDERACLYINFHHILTDGWSIDIYYRELF 1408 + + ++ F+L + P R+ L+ ++ +R ++ HHI++DG S I E Sbjct: 3220 TV-------ESFVQAFDLTKAPLLRVGLFKLAAKRHLFLLDMHHIISDGVSAGIIMEEFS 3272 Query: 1409 SLYQAFLHQQPPRLPEVKEDYFDWILEQKAWEESEAFVEHEQFWLKELAKPLPVLSLPSD 1468 LY+ LP + Y D+ + Q +S+ + EHE +WL + +PVL+LP+D Sbjct: 3273 KLYRG------EELPALSVHYKDFAVWQSELFQSDVYTEHENYWLNAFSGDIPVLNLPAD 3326 Query: 1469 HKAPAVQTYRGSFHKFTISGELYRKLKAHLETQQITANNFLLSAYFLLLHNLSQEQDIII 1528 P Q++ G F L L + Q T LL+AY +LL S ++DI++ Sbjct: 3327 FSRPLTQSFEGDCVSFQADKALLDDLHKLAQESQSTLFMVLLAAYNVLLAKYSGQEDIVV 3386 Query: 1529 GVPASGRNEQKWESVAGIFINTLCIRIHFQGITTFMELQDAVKHKVWSAMDKAQYPFDLL 1588 G P +GR+ E+V G+F+NTL +R + F + VK A YPF+ L Sbjct: 3387 GTPIAGRSHADIENVLGMFVNTLALRNYPVETKHFQAFLEEVKQNTLQAYAHQDYPFEAL 3446 Query: 1589 VEKVNPDRDLSRNPIYNVLFQF---------YDKLYLE----NEGISPFELSCLAQETNQ 1635 VEK++ RDLSRNP+++ +F D L LE G + F+L+ A E Sbjct: 3447 VEKLDIQRDLSRNPLFDTMFILQNLDQKAYELDGLKLEAYPAQAGNAKFDLTLEAHEDET 3506 Query: 1636 QIEISFEYNSDMYTDSTISRFAGYFLNIIGQVVDKPXXXXXXXXXXXXXXXXXXXSRFQG 1695 I + Y++ ++ +I R AG+FL ++ QVV F Sbjct: 3507 GIHFALVYSTKLFQRESIERMAGHFLQVLRQVVADQATALREISLLSEEERRIVTVDFNN 3566 Query: 1696 EQADLEDGQTIHGRFEAQVQKNPHAIALVYEEQQMTFQEVNGKANQLAWMLTGSGVQRNT 1755 A TI FE Q K P A+V + Q +T++E+N KANQLA +L +GV + + Sbjct: 3567 TFAAYPRDLTIQELFEQQAAKTPEHAAVVMDGQMLTYRELNEKANQLAHVLRQNGVGKES 3626 Query: 1756 PVGIFVDRSFSSVIGILAILKAGGAYVPLDPGYPEDRIAYILAHSGAKWLLTENRYLQSV 1815 VG+ DRS + GI+ ILKAGGAY+ LDP +P +R+AY+L G K +L + L V Sbjct: 3627 IVGLLADRSLEMITGIMGILKAGGAYLGLDPEHPSERLAYMLEDGGVKVVLVQKHLLPLV 3686 Query: 1816 AAFAHEEGIQIINLSPVKEQSAVSQMYLADYEDELSRE---NPRTGGHGPDRMYIMYTSG 1872 EG+ I L E+ L E NP D Y+MYTSG Sbjct: 3687 G-----EGLMPIVLE----------------EESLRPEDCGNPAIVNGASDLAYVMYTSG 3725 Query: 1873 STGKPKGVLVTHSNVLNFVTWSIGELQLQPKDALLLVTSISFDISVFEIFAALLSGSRLC 1932 STGKPKGV+V H NV V + +Q++ D ++ +I FD FEIF ALL G+ L Sbjct: 3726 STGKPKGVMVEHRNVTRLVMHT-NYVQVRESDRMIQTGAIGFDAMTFEIFGALLHGASLY 3784 Query: 1933 IASMEHLKDTECLLAYMEAQHI-TIWHSVPSLMVQLMTLLRHHPGRYRHSPVLQQLRHLM 1991 + S + L D E L ++ I T+W + P L QL + +P + LR L+ Sbjct: 3785 LVSKDVLLDAEKLGDFLRTNQITTMWLTSP-LFNQLS---QDNPAMF------DSLRALI 3834 Query: 1992 LGGEAWSTSLAASLRETFPQAEIRNMYGPTEATIWVSSYKPGPEIDESHPVMLIGRPIAN 2051 +GGEA S ++ P EI N YGPTE T + + Y +E P IG+PIAN Sbjct: 3835 VGGEALSPKHINRVKSALPDLEIWNGYGPTENTTFSTCYLIEQHFEEQIP---IGKPIAN 3891 Query: 2052 NRLIILDQYGNVCPPGVAGEIYIAGNNVTQGYYNDEEKTRMAFIPQ--SNGQIFYKTGDS 2109 + I+D P GV GE+ + G+ V +GY N E T F+P + G+ Y+TGD Sbjct: 3892 STAYIVDGNNQPQPIGVPGELCVGGDGVARGYVNKPELTAEKFVPNPFAPGETMYRTGDL 3951 Query: 2110 GRYLPEGNVEFTGRRDQLVKVRGYRIELGEIEQALKELTSLQQIAVTAVKDGETSKIVCL 2169 R+LP+G +E+ GR DQ VK+RGYRIELGEIE L + +++ V +++ K +C Sbjct: 3952 ARWLPDGTIEYLGRIDQQVKIRGYRIELGEIETVLSQQAQVKEAVVAVIEEANGQKALCA 4011 Query: 2170 Y-TGDQPVPQNQLKDAVRKRLPEYMIPAQFFHVERFLLTPNGKMDWRSMEKFVRE-TPGS 2227 Y +Q V +L++A+ K+LP YM+PA + +E+ LT NGK+D R++ + E T GS Sbjct: 4012 YFVPEQAVDAAELREAMSKQLPGYMVPAYYVQMEKLPLTANGKVDRRALPQPSGERTTGS 4071 Query: 2228 IEAAGIRNEVDKKLSEIWKKLLGIPAVGIQENFFDIGGNSLLVVQMQGMIQQEFFQDIPM 2287 A +N+ + KL +IW+++LGIPA+GI +NFF+IGG+SL + + + + F ++P+ Sbjct: 4072 AFVAA-QNDTEAKLQQIWQEVLGIPAIGIHDNFFEIGGHSLKAMNVITQVHKTFQVELPL 4130 Query: 2288 MDLFKYTSIEKISDYLQE 2305 LF +I +++ ++ E Sbjct: 4131 KALFATPTIHELAAHIAE 4148 Score = 598 bits (1542), Expect = e-169, Method: Compositional matrix adjust. Identities = 381/1203 (31%), Positives = 626/1203 (52%), Gaps = 83/1203 (6%) Query: 1132 FWNRPLPVSLAPAI----------------REQIKHPEAEIDVRLTGRADQSYTEIEQQI 1175 F R LP + P+ R+++ P + A Q+ EIE ++ Sbjct: 917 FLGRTLPSYMIPSFFIRLAEIPLTANGKVERKKLPKPAGAVVTGTAYAAPQN--EIEAKL 974 Query: 1176 ARIWGNLFQMPNIDIQDNFYELGGTSIMGIKIANRINEQYRVTMTIQDVFTHLTVASLGK 1235 A IW + + + I D+F++LGG S+ + + ++++ V + ++ +F H TVA L + Sbjct: 975 AEIWQQVLGISQVGIHDDFFDLGGHSLKAMTVVFQVSKALEVELPVKALFEHPTVAELAR 1034 Query: 1236 LVEQKLGTKTEAGAVNKQEVEYAKTSMPLSHAQRRIWFLQKMNPDLVAYNLPFIRYFDMA 1295 + + KTE A+ Q V A+ P+S AQ+R++ LQ+ + ++YN+ + Sbjct: 1035 FLSR--SEKTEYTAI--QPVA-AQEFYPVSSAQKRMYILQQFEGNGISYNISGAILLEGK 1089 Query: 1296 IDLELLQQAASFLAGRHLLMRTKYVLKDGNPVQEVLPAY-VPAVQSIDAAGQSDPELFVK 1354 +D A LA RH +RT + DG PVQ+V VP Q++ Sbjct: 1090 LDYARFASAVQQLAERHEALRTSFHRIDGEPVQKVHEEVEVPLFMLEAPEDQAE------ 1143 Query: 1355 MNIHQQKMKPFNLEMPP-YRIYLYTISDERACLYINFHHILTDGWSIDIYYRELFSLYQA 1413 I ++ ++PF+L + P R L + +R ++ HHI++DG S I RE LYQ Sbjct: 1144 -KIMREFVRPFDLGVAPLMRTGLLKLGKDRHLFLLDMHHIISDGVSSQILLREFAELYQG 1202 Query: 1414 FLHQQPPRLPEVKEDYFDWILEQKAWEESEAFVEHEQFWLKELAKPLPVLSLPSDHKAPA 1473 QP L Y D+ Q ++EA+ + EQ WL A +P+L+LP+D+ P+ Sbjct: 1203 -ADLQPLSL-----QYKDFAAWQNELFQTEAYKKQEQHWLNTFADEIPLLNLPTDYPRPS 1256 Query: 1474 VQTYRGSFHKFTISGELYRKLKAHLETQQITANNFLLSAYFLLLHNLSQEQDIIIGVPAS 1533 VQ++ G F EL +L+ T LL+AY +LL + ++DII+G P + Sbjct: 1257 VQSFAGDLVLFAAGKELLERLQQVASETGTTLYMILLAAYNVLLSKYTGQEDIIVGTPVA 1316 Query: 1534 GRNEQKWESVAGIFINTLCIRIHFQGITTFMELQDAVKHKVWSAMDKAQYPFDLLVEKVN 1593 GR+ E++ GIF+NTL +R TF + VK +A D YPF+ LVEK+ Sbjct: 1317 GRSHADVENIMGIFVNTLALRNQPASSKTFAQFLQEVKQNALAAYDHQDYPFEELVEKLA 1376 Query: 1594 PDRDLSRNPIYNVLFQFYD-------------KLYLENEGISPFELSCLAQETNQQIEIS 1640 RD+SRNP+++ LF + Y IS F+L+ A E+ I+ Sbjct: 1377 IQRDISRNPLFDTLFSLENANQQSLAIAELTASPYELFNKISKFDLALNASESPADIQFQ 1436 Query: 1641 FEYNSDMYTDSTISRFAGYFLNIIGQVVDKPXXXXXXXXXXXXXXXXXXXSRFQGEQADL 1700 + + ++ T+ R A ++L I+ + ++P + Sbjct: 1437 LTFATKLFKKETVERMARHYLEILRWISEQPTASLADIDMMTEAEKRTLLLNVNDTFVER 1496 Query: 1701 EDGQTIHGRFEAQVQKNPHAIALVYEEQQMTFQEVNGKANQLAWMLTGSGVQRNTPVGIF 1760 +H E Q + P +A+VYEE +T++E+N +ANQLA +L G +T +GI Sbjct: 1497 TAATALHQLVEEQAARTPDEVAVVYEEYALTYRELNARANQLARLLRSHGTGPDTLIGIM 1556 Query: 1761 VDRSFSSVIGILAILKAGGAYVPLDPGYPEDRIAYILAHSGAKWLLTENRYLQSVAAFAH 1820 VDRS V+G+LA+LKAGGAY P+DP YP +RI Y+L+ S A LLT+ R+LQ +AA+ Sbjct: 1557 VDRSPGMVVGMLAVLKAGGAYTPIDPSYPPERIQYMLSDSQAPILLTQ-RHLQELAAYQG 1615 Query: 1821 EEGIQIINLSPVKEQSAVSQMYLADYEDELSRENPRTGGHGPDRMYIMYTSGSTGKPKGV 1880 E II++ ++ A+ + ++ ++ D Y++YTSGSTG PKGV Sbjct: 1616 E----IIDV----DEEAIYTGADTNLDNVAGKD---------DLAYVIYTSGSTGNPKGV 1658 Query: 1881 LVTHSNVLNFVTWSIGELQLQPKDALLLVTSISFDISVFEIFAALLSGSRLCIASMEHLK 1940 +++H + N + W L +DA+L T SFD SV+E + L++G +L +A + + Sbjct: 1659 MISHQAICNHMLWMRETFPLTTEDAVLQKTPFSFDASVWEFYLPLITGGQLVLAKPDGHR 1718 Query: 1941 DTECLLAYMEAQHITIWHSVPSLMVQLMTLLRHHPGRYRHSPVLQQLRHLMLGGEAWSTS 2000 D + + + IT VPSL+ +MT PG L+ + GGEA + + Sbjct: 1719 DIAYMTRLIRDEKITTLQMVPSLLDLVMT----DPGW----SACTSLQRVFCGGEALTPA 1770 Query: 2001 LAASLRETFPQAEIRNMYGPTEATIWVSSYKPGPEIDESHPVMLIGRPIANNRLIILDQY 2060 L + ET QA++ N+YGPTE TI ++Y P P E + + IG+PI N RL +++ Sbjct: 1771 LVSRFYET-QQAQLINLYGPTETTI-DATYWPCPRQQE-YSAIPIGKPIDNVRLYVVNAS 1827 Query: 2061 GNVCPPGVAGEIYIAGNNVTQGYYNDEEKTRMAFI--PQSNGQIFYKTGDSGRYLPEGNV 2118 + P GVAGE+ IAG+ + +GY+ EE T+ +F+ P G Y+TGD RYLP+G++ Sbjct: 1828 NQLQPVGVAGELCIAGDGLARGYWQREELTKASFVDNPFEPGGTMYRTGDMVRYLPDGHI 1887 Query: 2119 EFTGRRDQLVKVRGYRIELGEIEQALKELTSLQQIAVTAVKDGETSKIVCLY-TGDQPVP 2177 E+ GR D VK+RG+RIELGEIE L + +++ + V A +DG+ + Y +Q + Sbjct: 1888 EYLGRIDHQVKIRGHRIELGEIEATLLQHEAVKAVVVMARQDGKGQNSLYAYVVAEQDIQ 1947 Query: 2178 QNQLKDAVRKRLPEYMIPAQFFHVERFLLTPNGKMDWRSMEKFVRETPGSIEAAGIRNEV 2237 +L+ + LP YM+P+ F +E+ L+ NGK+D +++ + + RNE Sbjct: 1948 TAELRTYLSATLPAYMVPSAFVFLEQLPLSANGKVDRKALPQPEDAAASAAVYVAPRNEW 2007 Query: 2238 DKKLSEIWKKLLGIPAVGIQENFFDIGGNSLLVVQMQGMIQQEFFQDIPMMDLFKYTSIE 2297 + KL+ IW+ +LG+ +G+ ++FF++GG+SL + + ++Q+ F D+P+ LF+ +I Sbjct: 2008 EAKLAAIWESVLGVEPIGVHDHFFELGGHSLKAMHVISLLQRSFQVDVPLKVLFESPTIA 2067 Query: 2298 KIS 2300 ++ Sbjct: 2068 GLA 2070 Score = 592 bits (1525), Expect = e-167, Method: Compositional matrix adjust. Identities = 363/1152 (31%), Positives = 590/1152 (51%), Gaps = 63/1152 (5%) Query: 1172 EQQIARIWGNLFQMPNIDIQDNFYELGGTSIMGIKIANRINEQYRVTMTIQDVFTHLTVA 1231 E ++A++W + +P + D+F+ LGG S+ +++ + ++ +Y+V + ++ +F T+ Sbjct: 5125 EARLAQVWEQVLNVPQVGALDDFFALGGHSLRAMRVLSSMHNEYQVDIPLRILFEKPTIQ 5184 Query: 1232 SLGKLVEQKLGTKTEAGAVNKQEVEYAKTSMPLSHAQRRIWFLQKMNPDLVAYNLPFIRY 1291 L +E+ T G V E + P+S AQ+R++ L + ++YN+P Sbjct: 5185 ELAAFIEE-----TAKGNVFSIEPVQKQAYYPVSSAQKRMYILDQFEGVGISYNMPSTML 5239 Query: 1292 FDMAIDLELLQQAASFLAGRHLLMRTKYVLKDGNPVQEVLPAYVPAVQSIDAAGQSDPEL 1351 + ++ ++ A L RH +RT + + +G PVQ + A+ + Q EL Sbjct: 5240 IEGKLERTRVEAAFQRLIARHESLRTSFAVVNGEPVQNIHEDVPFALAYSEVTEQEAREL 5299 Query: 1352 FVKMNIHQQKMKPFNLEMPPY-RIYLYTISDERACLYINFHHILTDGWSIDIYYRELFSL 1410 + ++PF+LE+ P R+ L I ++R L+ + HH ++DG S I E L Sbjct: 5300 VSSL------VQPFDLEVAPLIRVSLLKIGEDRYVLFTDMHHSISDGVSSGILLAEWVQL 5353 Query: 1411 YQAFLHQQPPRLPEVKEDYFDWILEQKAWEESEAFVEHEQFWLKELAKPLPVLSLPSDHK 1470 YQ + LPE++ Y D+ + Q+ + +S AF + E +WL+ A +PVL+LP+D Sbjct: 5354 YQGDV------LPELRIQYKDFAVWQQEFSQSAAFHKQEAYWLQTFADDIPVLNLPTDFT 5407 Query: 1471 APAVQTYRGSFHKFTISGELYRKLKAHLETQQITANNFLLSAYFLLLHNLSQEQDIIIGV 1530 P+ Q++ G L L + T LL+AY +LL + ++DII+G Sbjct: 5408 RPSTQSFAGDQCTIGAGKALTEGLHQLAQATGTTLYMVLLAAYNVLLAKYAGQEDIIVGT 5467 Query: 1531 PASGRNEQKWESVAGIFINTLCIRIHFQGITTFMELQDAVKHKVWSAMDKAQYPFDLLVE 1590 P +GR+ E + G+F+NTL +R Q TF E VK A YPF+ LVE Sbjct: 5468 PITGRSHADLEPIVGMFVNTLAMRNKPQREKTFSEFLQEVKQNALDAYGHQDYPFEELVE 5527 Query: 1591 KVNPDRDLSRNPIYNVLFQFYDK----LYLENEGISPF-----------ELSCLAQETNQ 1635 K+ RDLSRNP+++ +F F + + L ++PF +L+ A E + Sbjct: 5528 KLAIARDLSRNPLFDTVFTFQNSTEEVMTLPECTLAPFMTDETGQHAKFDLTFSATEERE 5587 Query: 1636 QIEISFEYNSDMYTDSTISRFAGYFLNIIGQVVDKPXXXXXXXXXXXXXXXXXXXSRFQG 1695 ++ I EY++ ++T T+ RF+ +FL I +V P + F Sbjct: 5588 EMTIGVEYSTSLFTRETMERFSRHFLTIAASIVQNPHIRLGEIDMLLPEEKQQILAGFND 5647 Query: 1696 EQADLEDGQTIHGRFEAQVQKNPHAIALVYEEQQMTFQEVNGKANQLAWMLTGSGVQRNT 1755 +T+H FE QV K P AL++ EQ +T+ E+N +AN+LA +L GV + Sbjct: 5648 TAVSYALDKTLHQLFEEQVDKTPDQAALLFSEQSLTYSELNERANRLARVLRAKGVGPDR 5707 Query: 1756 PVGIFVDRSFSSVIGILAILKAGGAYVPLDPGYPEDRIAYILAHSGAKWLLTENRYLQSV 1815 V I +RS VIGIL ILKAGGAYVP+DPGYP++RI Y+L S A LL++ L + Sbjct: 5708 LVAIMAERSPEMVIGILGILKAGGAYVPVDPGYPQERIQYLLEDSNAALLLSQAHLLPLL 5767 Query: 1816 AAFAHEEGIQIINLSPVKEQSAVSQMYLADYEDELSRENPRTGGHGPDRMYIMYTSGSTG 1875 A + E + ++L+ A+ + LS N D Y++YTSG+TG Sbjct: 5768 AQVSSELP-ECLDLN-------------AELDAGLSGSNLPAVNQPTDLAYVIYTSGTTG 5813 Query: 1876 KPKGVLVTHSNVLNFVTWSIGELQLQPKDALLLVTSISFDISVFEIFAALLSGSRLCIAS 1935 KPKGV++ H ++N + W E P D L V S +FD V +FA LL G+ + Sbjct: 5814 KPKGVMIPHQGIVNCLQWRRDEYGFGPSDKALQVFSFAFDGFVASLFAPLLGGATCVLPQ 5873 Query: 1936 MEHLKDTECLLAYMEAQHITIWHSVPSLMVQLMTLLRHHPGRYRHSPVLQQLRHLMLGGE 1995 KD L M A +T ++ VPSL ++ + QLR + LGGE Sbjct: 5874 EAAAKDPVALKKLMAATEVTHYYGVPSLFQAILDC--------STTTDFNQLRCVTLGGE 5925 Query: 1996 AWSTSLAASLRETFPQAEIRNMYGPTEATIWVSSYKPGPEIDESHPVMLIGRPIANNRLI 2055 L +E P EI N YGPTE ++ + + E+ + IGRP+AN ++ Sbjct: 5926 KLPVQLVQKTKEKHPAIEINNEYGPTENSVVTTISRS----IEAGQAITIGRPLANVQVY 5981 Query: 2056 ILDQYGNVCPPGVAGEIYIAGNNVTQGYYNDEEKTRMAFI--PQSNGQIFYKTGDSGRYL 2113 I+D+ ++ P GV GE+ I G + +GY N E T F+ P G+ YKTGD ++ Sbjct: 5982 IVDEQHHLQPIGVVGELCIGGAGLARGYLNKPELTAEKFVANPFRPGERMYKTGDLVKWR 6041 Query: 2114 PEGNVEFTGRRDQLVKVRGYRIELGEIEQALKELTSLQQIAVTAVKDGET--SKIVCLYT 2171 +G +E+ GR D+ VKVRGYRIE+GEIE A+ + Q V A D T S + + Sbjct: 6042 TDGTIEYIGRADEQVKVRGYRIEIGEIESAVLAYQGIDQAVVVARDDDATAGSYLCAYFV 6101 Query: 2172 GDQPVPQNQLKDAVRKRLPEYMIPAQFFHVERFLLTPNGKMDWRSMEKFVRETPGSIEAA 2231 V + L+ + K LP YMIP+ F +++ L+ NGK+D +++ K + + E Sbjct: 6102 AATAVSVSGLRSHLAKELPAYMIPSYFVELDQLPLSANGKVDRKALPKPQQSDATTREYV 6161 Query: 2232 GIRNEVDKKLSEIWKKLLGIPAVGIQENFFDIGGNSLLVVQMQGMIQQEFFQDIPMMDLF 2291 RN +++L+ IW+++LG+ +GI + FF++GG+SL + + + ++P+ +F Sbjct: 6162 APRNATEQQLAAIWQEVLGVEPIGITDQFFELGGHSLKATLLIAKVYEYMQIELPLNLIF 6221 Query: 2292 KYTSIEKISDYL 2303 +Y +IEK++D++ Sbjct: 6222 QYPTIEKVADFI 6233 Score = 567 bits (1460), Expect = e-159, Method: Compositional matrix adjust. Identities = 369/1197 (30%), Positives = 607/1197 (50%), Gaps = 67/1197 (5%) Query: 1146 REQIKHPEAEIDVRLTGRA-DQSYTEIEQQIARIWGNLFQMPNIDIQDNFYELGGTSIMG 1204 R + P E R TG A + + E ++ +IW + +P I I DNF+E+GG S+ Sbjct: 4057 RRALPQPSGE---RTTGSAFVAAQNDTEAKLQQIWQEVLGIPAIGIHDNFFEIGGHSLKA 4113 Query: 1205 IKIANRINEQYRVTMTIQDVFTHLTVASLGKLVEQKLGTKTEAGAVNKQEVEYAKTSMPL 1264 + + ++++ ++V + ++ +F T+ L + + + E Q VE A P+ Sbjct: 4114 MNVITQVHKTFQVELPLKALFATPTIHELAAHIAESAFEQFE----TIQPVEPA-AFYPV 4168 Query: 1265 SHAQRRIWFLQKMNPDLVAYNLPFIRYFDMAIDLELLQQAASFLAGRHLLMRTKYVLKDG 1324 S AQ+R++ L + ++YN+P + + +D + A L RH +RT + +G Sbjct: 4169 SFAQKRMYILHQFEGSGISYNVPSVLVLEGKLDYDRFAAAIQSLVKRHESLRTSFHSVNG 4228 Query: 1325 NPVQEVLPAYVPAVQSIDAAGQSDPELFVKMNIHQQKMKPFNLEMPP-YRIYLYTISDER 1383 P+Q V P V+ ++A L Q+ ++PF+LE+ P +R+ L + ER Sbjct: 4229 EPLQRVHPDVELPVRLLEATEDQSESLI------QELIQPFDLEIAPLFRVNLIKLGAER 4282 Query: 1384 ACLYINFHHILTDGWSIDIYYRELFSLYQAFLHQQPPRLPEVKEDYFDWILEQKAWEESE 1443 +++ HHI++DG S+ + E+ SLY +L +++ Y D+ + Q +S+ Sbjct: 4283 HLFFMDMHHIISDGVSLAVIVEEIASLYAG------KQLSDLRIQYKDFAVWQTKLAQSD 4336 Query: 1444 AFVEHEQFWLKELAKPLPVLSLPSDHKAPAVQTYRGSFHKFTISGELYRKLKAHLETQQI 1503 F + E FW + A +P+L+LP D+ P+VQ++ G L +L+ Sbjct: 4337 RFQKQEDFWTRTFAGEIPLLNLPHDYPRPSVQSFDGDTVALGTGHHLLEQLRKLAAETGT 4396 Query: 1504 TANNFLLSAYFLLLHNLSQEQDIIIGVPASGRNEQKWESVAGIFINTLCIRIHFQGITTF 1563 T LL+AY +LL + +++I++G P +GR+ E + G+F+NTL ++ G +F Sbjct: 4397 TLFMVLLAAYHVLLSKYAGQEEIVVGTPIAGRSHADVERIVGMFVNTLALKNTAAGSLSF 4456 Query: 1564 MELQDAVKHKVWSAMDKAQYPFDLLVEKVNPDRDLSRNPIYNVLFQ-------------F 1610 + VK A + YPF+ LVEK+ RDLSRNP+++ +F Sbjct: 4457 RAFLEDVKQNALHAFEHQDYPFEHLVEKLQVRRDLSRNPLFDTMFSLGLAESAEGEVADL 4516 Query: 1611 YDKLYLENEGISPFELSCLAQETNQQIEISFEYNSDMYTDSTISRFAGYFLNIIGQVVDK 1670 Y N I+ F+LS A E + + F Y + ++ T+ R A +++ ++ + Sbjct: 4517 KVSPYPVNGHIAKFDLSLDAMEKQDGLLVQFSYCTKLFAKETVDRLAAHYVQLLQTITAD 4576 Query: 1671 PXXXXXXXXXXXXXXXXXXXSRFQGEQADLEDGQTIHGRFEAQVQKNPHAIALVYEEQQM 1730 P F + +T FE QV+K P+ IA+++ +Q+ Sbjct: 4577 PDIELARISVLSKAETEHMLHSFLATKTAYPTDKTFQKLFEEQVEKTPNEIAVLFGNEQL 4636 Query: 1731 TFQEVNGKANQLAWMLTGSGVQRNTPVGIFVDRSFSSVIGILAILKAGGAYVPLDPGYPE 1790 T+QE+N KANQLA +L GV+ + VGI VDRS VIG+LA+LKAGG +VP+DP YP Sbjct: 4637 TYQELNAKANQLARVLRRKGVKPESTVGILVDRSLYMVIGMLAVLKAGGTFVPIDPDYPL 4696 Query: 1791 DRIAYILAHSGAKWLLTENRYLQSVAAFAHEEGIQIINLSPVKEQSAVSQMYLADYEDEL 1850 +R A++L S AK LLT + + S AF +E + + V Q + E Sbjct: 4697 ERQAFMLEDSEAKLLLTLQK-MNSQVAFPYE--------TFYLDTETVDQEETGNLEHVA 4747 Query: 1851 SRENPRTGGHGPDRMYIMYTSGSTGKPKGVLVTHSNVLNFVTWSIGELQLQPKDALLL-V 1909 EN YI+YTSG+TGKPKGV++ H + N E L LL + Sbjct: 4748 QPEN---------VAYIIYTSGTTGKPKGVVIEHRSYANVAFAWKDEYHLDSFPVRLLQM 4798 Query: 1910 TSISFDISVFEIFAALLSGSRLCIASMEHLKDTECLLAYMEAQHITIWHSVPSLMVQLMT 1969 S +FD+S + ALL+G +L I D L + ITI+ + P+L++ LM Sbjct: 4799 ASFAFDVSTGDFARALLTGGQLVICPNGVKMDPASLYETIRRHEITIFEATPALIMPLMH 4858 Query: 1970 LLRHHPGRYRHSPVLQQLRHLMLGGEAWSTSLAASLRETFPQA-EIRNMYGPTEATIWVS 2028 + Y + + Q++ L+LG ++ +L F Q I N YG TEA I S Sbjct: 4859 YV------YENELDMSQMKLLILGADSCPAEDFKTLLARFGQKMRIINSYGVTEACIDTS 4912 Query: 2029 SYKPGPEIDESHPVMLIGRPIANNRLIILDQYGNVCPPGVAGEIYIAGNNVTQGYYNDEE 2088 Y+ + IG+P+ N + ++D + N+ P GV GE+ I G V +GY N E Sbjct: 4913 YYEETDVTAIRSGTVPIGKPLPNMTMYVVDAHLNLQPVGVVGELCIGGAGVARGYLNRPE 4972 Query: 2089 KTRMAFIPQ--SNGQIFYKTGDSGRYLPEGNVEFTGRRDQLVKVRGYRIELGEIEQALKE 2146 T F+P + G+ Y+TGD ++ +GNVEF GR D VK+RG RIELGEIE L++ Sbjct: 4973 LTEEKFVPNPFAPGERLYRTGDLAKWRADGNVEFLGRNDHQVKIRGVRIELGEIETQLRK 5032 Query: 2147 LTSLQQIAVTAVKDGETSKIVCLY-TGDQPVPQNQLKDAVRKRLPEYMIPAQFFHVERFL 2205 L + + V A +D K +C Y D + +L+ + K LP+ MIPA F ++ Sbjct: 5033 LDGITEAVVVAREDRGQEKELCAYVVADHKLDTAELRANLLKELPQAMIPAYFVTLDALP 5092 Query: 2206 LTPNGKMDWRSMEKFVRETPGSIEAAGIRNEVDKKLSEIWKKLLGIPAVGIQENFFDIGG 2265 LT NGK+D RS+ + E R+ + +L+++W+++L +P VG ++FF +GG Sbjct: 5093 LTANGKVDRRSLPAPDVTMLRTTEYVAPRSVWEARLAQVWEQVLNVPQVGALDDFFALGG 5152 Query: 2266 NSLLVVQMQGMIQQEFFQDIPMMDLFKYTSIEKISDYLQEHTVK--VSSVETGQKRA 2320 +SL +++ + E+ DIP+ LF+ +I++++ +++E T K V S+E QK+A Sbjct: 5153 HSLRAMRVLSSMHNEYQVDIPLRILFEKPTIQELAAFIEE-TAKGNVFSIEPVQKQA 5208 Score = 374 bits (960), Expect = e-101, Method: Compositional matrix adjust. Identities = 297/1073 (27%), Positives = 505/1073 (47%), Gaps = 80/1073 (7%) Query: 1263 PLSHAQRRIWFLQKMNPDLVAYNLPFIRYFDMAIDLELLQQAASFLAGRHLLMRTKYVLK 1322 PL+ Q + F + AY L + L L +++ + L + ++RT +V + Sbjct: 12 PLTPLQEGMLFHAVTDTGSSAYCLQMSATIEGDFHLPLFEKSLNKLVENYEVLRTAFVYQ 71 Query: 1323 D-GNPVQEVLPAYVPAVQSIDAAGQSDPELFVKMNIHQQKMKPFNLEMPP-YRIYLYTIS 1380 + P Q V V + A E + + ++ F+L + ++ + Sbjct: 72 NMQRPRQVVFKERKVTVPCENIAHLPSAEQDAYIQAYTKQHHAFDLTKDNLMKAAIFQTA 131 Query: 1381 DERACLYINFHHILTDGWSIDIYYRELFSLYQAFLHQQP-PRLPEVKEDYFDWILEQKAW 1439 + + L FHHI+ DGW++ + +L + Y A +P PR E + Y ++I W Sbjct: 132 ENKYRLVWAFHHIIVDGWTLGVLLHKLLTYYAALRKGEPIPR--EATKPYSEYI----KW 185 Query: 1440 EESEAFVEHEQFWLKELAKPLPVLSLPSDHKAPAVQTYRGSFHKFTISGELYRKLKAHLE 1499 + + E +W LA + P Y FTI+ E ++L Sbjct: 186 LDKQNKDEALAYWQNYLAGYDHQAAFPKKKLGTEASRYEHVEAMFTIAPEKTQQLIQIAN 245 Query: 1500 TQQITANNFLLSAYFLLLHNLSQEQDIIIGVPASGR--NEQKWESVAGIFINTLCIRIHF 1557 Q T ++ + + +L D++ G SGR Q ES+ G+FINT+ R+ Sbjct: 246 QNQATMSSVFQALWGILASTYKNADDVVFGSVVSGRPPQIQGIESMVGLFINTIPTRVQT 305 Query: 1558 QGITTFMELQDAVKHKVWSAMDKAQYPFDLLVEKVNPDRDLSRNPI-YNVLFQFYD---- 1612 TF EL V+ + A+ A Y F L E + L + I + V F+ Y Sbjct: 306 NKQQTFSELLQTVQKQ---ALASATYDFAPLYE-IQSTTVLKQELIDHLVTFENYPDHSM 361 Query: 1613 KLYLENEGI----------SPFELSCL-AQETNQQIEISFEYNSDMYTDSTISRFAGYFL 1661 K E+ G + ++L+ + A + ++ + YN+ +Y S ++R G+ Sbjct: 362 KHLEESLGFQFTVESGDEQTSYDLNVVVALAPSNELYVKLSYNAAVYESSFVNRIEGHLR 421 Query: 1662 NIIGQVVDKPXXXXXXXXXXXXXXXXXXXSRFQGEQADLEDGQTIHGRFEAQVQKNPHAI 1721 +I QV+ P + A+ +TI Q + P Sbjct: 422 TVIDQVIGNPHVHLHEIGIITEEEKQQLLVAYNDTAAEYPRDKTIFELIAEQASRTPAKA 481 Query: 1722 ALVYEEQQMTFQEVNGKANQLAWMLTGSGVQRNTPVGIFVDRSFSSVIGILAILKAGGAY 1781 A+V E +T+QE+ ++ QLA L G+ + V I + S ++ I+A+L++G AY Sbjct: 482 AVVCGEDTLTYQELMERSAQLANALREKGIASGSIVSIMAEHSLELIVAIMAVLRSGAAY 541 Query: 1782 VPLDPGYPEDRIAYILAHSGAKWLLTENRYLQSVAAFAHEEGIQIINLSPVKEQSAVSQM 1841 +P+DP YP+DRI Y+L S LLT++ +LQ FA S + Sbjct: 542 LPIDPEYPQDRIQYLLDDSQTTLLLTQS-HLQPNIRFAG------------------SVL 582 Query: 1842 YLAD---YEDELSRENPRTGGHGPDRM-YIMYTSGSTGKPKGVLVTHSNVLNFVTWSIGE 1897 YL D YE + P + PD + Y++YTSGSTG PKG ++TH ++N++ W+ + Sbjct: 583 YLDDRSLYEGGSTSFAPESK---PDDLAYMIYTSGSTGNPKGAMITHQGLVNYIWWA-NK 638 Query: 1898 LQLQPKDA-LLLVTSISFDISVFEIFAALLSGSRLCIASMEHLKDTECLLAYMEAQHITI 1956 + +Q + L +SISFD++V IF LLSG+ + + + +L ++ + I Sbjct: 639 VYVQGEAVDFPLYSSISFDLTVTSIFTPLLSGNTIHV--YRGADKVQVILDIIKDNKVGI 696 Query: 1957 WHSVPSLMVQLMTLLRHHPGRYRHSPVLQQLRHLMLGGEAWSTSLAASLRETFPQ-AEIR 2015 P+ + L+ H G+ +R ++GGE T LA + + F + +I Sbjct: 697 IKLTPTHL----KLIEHIDGK------ASSIRRFIVGGENLPTKLAKQIYDHFGENVQIF 746 Query: 2016 NMYGPTEATI--WVSSYKPGPEIDESHPVMLIGRPIANNRLIILDQYGNVCPPGVAGEIY 2073 N YGPTE + + Y P ES P IG P N +L +LD P G GE+Y Sbjct: 747 NEYGPTETVVGCMIYLYDPQTTTQESVP---IGVPADNVQLYLLDASMQPVPVGSLGEMY 803 Query: 2074 IAGNNVTQGYYNDEEKTRMAFI--PQSNGQIFYKTGDSGRYLPEGNVEFTGRRDQLVKVR 2131 IAG+ V +GY+N E T+ FI P G Y+TGD ++LP+GN+E+ GR D VK+R Sbjct: 804 IAGDGVAKGYFNRPELTKEKFIDNPFRPGTKMYRTGDLAKWLPDGNMEYAGRMDYQVKIR 863 Query: 2132 GYRIELGEIEQALKELTSLQQIAVTAVKDGETSKIVCLY-TGDQPVPQNQLKDAVRKRLP 2190 G+RIE+GEIE L + ++++ V KD ++ Y ++ + +L++ + + LP Sbjct: 864 GHRIEMGEIETRLTQHEAVKEAVVIVEKDESGQNVLYAYLVSERELTVAELREFLGRTLP 923 Query: 2191 EYMIPAQFFHVERFLLTPNGKMDWRSMEKFVRETPGSIEAAGIRNEVDKKLSEIWKKLLG 2250 YMIP+ F + LT NGK++ + + K A +NE++ KL+EIW+++LG Sbjct: 924 SYMIPSFFIRLAEIPLTANGKVERKKLPKPAGAVVTGTAYAAPQNEIEAKLAEIWQQVLG 983 Query: 2251 IPAVGIQENFFDIGGNSLLVVQMQGMIQQEFFQDIPMMDLFKYTSIEKISDYL 2303 I VGI ++FFD+GG+SL + + + + ++P+ LF++ ++ +++ +L Sbjct: 984 ISQVGIHDDFFDLGGHSLKAMTVVFQVSKALEVELPVKALFEHPTVAELARFL 1036 >ref|ZP_00110897.1| COG3319: Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Nostoc punctiforme] Length = 4389 Score = 630 bits (1624), Expect = e-178, Method: Compositional matrix adjust. Identities = 388/1208 (32%), Positives = 640/1208 (52%), Gaps = 104/1208 (8%) Query: 1171 IEQQIARIWGNLFQMPNIDIQDNFYELGGTSIMGIKIANRINEQYRVTMTIQDVFTHLTV 1230 +E+ +A +W + ++ + I DNF+ELGG S++ ++ +RI +++ + ++++F TV Sbjct: 1005 MEEMLALLWTQVLKVELLGIHDNFFELGGHSLLATQLVSRIRNVFKLELPLRELFARATV 1064 Query: 1231 ASLGKLVEQ------KLGTKTEAGAVNKQEVEYAK---------TSMPLSHAQRRIWFLQ 1275 A L K + Q +L + + + Q++E ++ +PLS+AQ+R+WFL Sbjct: 1065 AELAKSIRQLQQQALRLTSAPLGTSRSVQDLELSEPPILPKMRDAELPLSYAQQRLWFLD 1124 Query: 1276 KMNPDLVAYNLPFIRYFDMAIDLELLQQAASFLAGRHLLMRTKYVLKDGNPVQEVLPAYV 1335 + P+ YN+P ++ L+Q+ + RH +RT ++ DG P Q + Sbjct: 1125 QFEPNSAFYNIPMALRLVGNLNQPALEQSLLEIIHRHEALRTNFIRVDGKPSQIIQTQTN 1184 Query: 1336 PAVQSIDAA--GQSDPELFVKMNIHQQKMKPFNLEMPPY-RIYLYTISDERACLYINFHH 1392 V ID +D E+ + QQ ++PF+L R L +S L + HH Sbjct: 1185 WTVSVIDLKYLSTTDQEITSQELARQQAIEPFDLANGALIRTTLLVLSQTEHILLVCMHH 1244 Query: 1393 ILTDGWSIDIYYRELFSLYQAFLHQQPPRLPEVKEDYFDWILEQKAWEESEAFVEHEQFW 1452 +++DGWS+ ++ +EL +LY A+ QP L + Y D+ + Q+ W + +W Sbjct: 1245 VVSDGWSMGVFVQELAALYDAYAQGQPSPLTPLPIQYADFAIWQREWLQGNVLQNQLTYW 1304 Query: 1453 LKELAKPLPVLSLPSDHKAPAVQTYRGSFHKFTISGELYRKLKAHLETQQITANNFLLSA 1512 ++LA +LSLP+D PAVQT+ G++ KF +S EL +L + Q +T LL+A Sbjct: 1305 QQQLANAPALLSLPTDRPRPAVQTFAGAYQKFALSAELTGRLIQLSQKQGVTLFMTLLAA 1364 Query: 1513 YFLLLHNLSQEQDIIIGVPASGRNEQKWESVAGIFINTLCIRIHFQGITTFMELQDAVKH 1572 + LL+ + +DI++G P + R+ + E + G F+NTL +R G +F EL V+ Sbjct: 1365 FDTLLYRYTGTEDILVGSPIANRDRSEIEGLIGFFVNTLVMRTDLAGNPSFSELLTRVRE 1424 Query: 1573 KVWSAMDKAQYPFDLLVEKVNPDRDLSRNPIYNVLFQFYDKLYLENEGISPFEL------ 1626 A PF++LVE + P+RDLS P++ V+F L+N IS EL Sbjct: 1425 IAMEAYSHQHLPFEMLVEALQPERDLSHTPLFQVMFT------LQNAPISTVELNQLSVS 1478 Query: 1627 SCLAQETNQQIEIS-------------FEYNSDMYTDSTISRFAGYFLNIIGQVVDKPXX 1673 S L + T + +++ +EY++D++ STI R G+F+ ++ ++ P Sbjct: 1479 STLIEGTTAKFDLTLSMENTATGVVGVWEYSTDLFDASTIERMTGHFVTLLESIIANPQQ 1538 Query: 1674 XXXXXXXXXXXXXXXXXSRFQGEQADLEDGQTIHGRFEAQVQKNPHAIALVYEEQQMTFQ 1733 + QAD + +H FE QV + P A+A+V+E QQ+T+Q Sbjct: 1539 SISQLPLLTEIEQQQLLVEWNNTQADYPLDKCLHQLFEEQVARTPDAVAVVFENQQLTYQ 1598 Query: 1734 EVNGKANQLAWMLTGSGVQRNTPVGIFVDRSFSSVIGILAILKAGGAYVPLDPGYPEDRI 1793 ++N +AN+LA L GV + VGI ++RS V+G+L ILKAGGAYVPLDP YP+DR+ Sbjct: 1599 QLNCRANKLAHYLQSLGVGADVLVGICLERSLLMVVGLLGILKAGGAYVPLDPDYPQDRL 1658 Query: 1794 AYILAHSGAKWLLTENRYLQSVAAFAHEEGIQIINLSPVKEQSAVSQMYL-ADYE--DEL 1850 +++L + + LLT+ + + + Q +YL D++ + Sbjct: 1659 SFMLEDAQVRVLLTQQQLKKKLP------------------QHQGQDIYLDTDWQFISQS 1700 Query: 1851 SRENPRTGGHGPDRMYIMYTSGSTGKPKGVLVTHSNVLNFVTWSIGELQLQPKDALLLVT 1910 S+ENP T G + Y++YTSGSTGKPKG + TH + N + W QL D +L T Sbjct: 1701 SQENPITTVQGSNLAYVIYTSGSTGKPKGAMNTHLGICNRLLWMQQAYQLTDVDCILQKT 1760 Query: 1911 SISFDISVFEIFAALLSGSRLCIASMEHLKDTECLLAYMEAQHITIWHSVPSLMVQLMTL 1970 SFD+SV+E F L++G+RL +A KD+ L+ + Q +T H VPS M+Q+ Sbjct: 1761 PFSFDVSVWEFFWPLITGARLVVAKAGGHKDSAYLVNLILEQQVTHVHFVPS-MLQV--- 1816 Query: 1971 LRHHPGRYRHSPVLQQLRHL---MLGGEAWSTSLAASLRETF---PQAEIRNMYGPTEAT 2024 + P L+ R L + GEA L L+E F + E+ N+YGPTEA Sbjct: 1817 -------FLEEPSLENCRSLKRFICSGEA----LPVELQERFFARLECELHNLYGPTEAA 1865 Query: 2025 IWVSSYKPGPEIDESHPVMLIGRPIANNRLIILDQYGNVCPPGVAGEIYIAGNNVTQGYY 2084 I V+ ++ P + + ++ IG+PIAN ++ ILD++ P GVAGE++I G + +GY Sbjct: 1866 IDVTYWQCFP--NGNLRIVPIGQPIANTQIYILDEHLQPVPVGVAGELHIGGAGLARGYL 1923 Query: 2085 NDEEKTRMAFI--PQSNGQIFYKTGDSGRYLPEGNVEFTGRRDQLVKVRGYRIELGEIEQ 2142 N E T+ FI P N ++ YKTGD RYLP+G +E+ R D VK+RG+RIELGEIE Sbjct: 1924 NRPELTKEKFISNPFENSKL-YKTGDLARYLPDGTIEYIERIDNQVKIRGFRIELGEIEV 1982 Query: 2143 ALKELTSLQQIAVTAVKDGETSKIVCLYTGDQPVPQ-------NQLKDAVRKRLPEYMIP 2195 L + +Q V A + K + Y VP N+L+ ++ +LP+YM+P Sbjct: 1983 LLNQYEEVQASCVIAREGTTGDKCLVAYI----VPHQHSKPTTNELRQFLKAKLPDYMVP 2038 Query: 2196 AQFFHVERFLLTPNGKMDWRSMEKFVRETPGSIEAAGIRNEVDKKLSEIWKKLLGIPAVG 2255 + F +E LT NGK+D R++ + + R +++ L++ W ++L +P VG Sbjct: 2039 SAFVILESMPLTSNGKVDRRALPAPDLYSEIKDKYVAPRTPIEEILAQTWSQVLQLPQVG 2098 Query: 2256 IQENFFDIGGNSLLVVQMQGMIQQEFFQDIPMMDLFKYTSIEKIS---DYLQEHTVKVSS 2312 I +NFF++GG+SLL Q+ I+ F ++P+ +LF ++ +++ + LQ+ ++++S Sbjct: 2099 IHDNFFELGGHSLLATQLVSRIRNIFKVELPLRELFAAATLAELAREIEQLQQQVLRLTS 2158 Query: 2313 VETGQKRA 2320 G R+ Sbjct: 2159 APLGTSRS 2166 Score = 573 bits (1477), Expect = e-161, Method: Compositional matrix adjust. Identities = 376/1209 (31%), Positives = 606/1209 (50%), Gaps = 101/1209 (8%) Query: 1169 TEIEQQIARIWGNLFQMPNIDIQDNFYELGGTSIMGIKIANRINEQYRVTMTIQDVFTHL 1228 T IE+ +A+ W + Q+P + I DNF+ELGG S++ ++ +RI ++V + ++++F Sbjct: 2078 TPIEEILAQTWSQVLQLPQVGIHDNFFELGGHSLLATQLVSRIRNIFKVELPLRELFAAA 2137 Query: 1229 TVASLGKLVEQ---KLGTKTEAGAVNKQEVEYAKTSMP------------LSHAQRRIWF 1273 T+A L + +EQ ++ T A + V+ + S P LS+AQ+R+WF Sbjct: 2138 TLAELAREIEQLQQQVLRLTSAPLGTSRSVQDLQLSAPPILPRAENALLALSYAQQRLWF 2197 Query: 1274 LQKMNPDLVAYNLPFIRYFDMAIDLELLQQAASFLAGRHLLMRTKYVLKDGNPVQ--EVL 1331 L + P+ YN+ +++ L+Q+ + RH +RT ++ DG Q + Sbjct: 2198 LDQFEPNSPFYNMSIALRLAGTVEVAALEQSFQEIIHRHEALRTNFITVDGQATQIIQTE 2257 Query: 1332 PAYVPAVQSIDAAGQSDPELFVKMNIHQQKMKPFNLEMPPY-RIYLYTISDERACLYINF 1390 + +V + + E + + QQ ++PF L R L +S+ L + Sbjct: 2258 TNWTVSVVDLKHLSTTKQETASQQLVQQQAIQPFELATQALVRATLVVLSETEHILLMCI 2317 Query: 1391 HHILTDGWSIDIYYRELFSLYQAFLHQQPPRLPEVKEDYFDWILEQKAWEESEAFVEHEQ 1450 HHI++DGWSI ++ +EL +LY A+ + L + Y D+ L Q+ W + E Sbjct: 2318 HHIVSDGWSIGLFLQELATLYNAYSQGKSSTLAPLPIQYADFALWQREWLQGEVLQSQLS 2377 Query: 1451 FWLKELAKPLPVLSLPSDHKAPAVQTYRGSFHKFTISGELYRKLKAHLETQQITANNFLL 1510 +W ++LA +LSLP+D PAVQTY+G+ +F +S EL KL + Q +T LL Sbjct: 2378 YWQQKLASAPTLLSLPTDRPRPAVQTYQGTHQEFALSEELTGKLAKLSQEQGVTLFMTLL 2437 Query: 1511 SAYFLLLHNLSQEQDIIIGVPASGRNEQKWESVAGIFINTLCIRIHFQGITTFMELQDAV 1570 +A+ LL+ + +DI++G P + R+ + E + G F+NTL +R G +F EL V Sbjct: 2438 AAFDTLLYRYTGTEDILVGSPIANRDRSEIEGLIGFFVNTLVMRTDLSGNPSFSELLGRV 2497 Query: 1571 KHKVWSAMDKAQYPFDLLVEKVNPDRDLSRNPIYNVLFQFYDKLY--LENEGI------- 1621 + A PF++LVE + P+RDLS P++ V+F + LE G+ Sbjct: 2498 REMAMEAYSHQHLPFEMLVEALQPERDLSHTPLFQVMFVLQNAPTSGLELTGLTVSSLPI 2557 Query: 1622 ----SPFELSCLAQETNQQIEISFEYNSDMYTDSTISRFAGYFLNIIGQVVDKPXXXXXX 1677 S F+L+ + Q T + +EYN+D++ STI R G+F+ ++ ++ P Sbjct: 2558 KGTTSRFDLTLIMQNTPTGLVGVWEYNTDLFDASTIERMTGHFVTLLEGIIANPEERISQ 2617 Query: 1678 XXXXXXXXXXXXXSRFQGEQADLEDGQTIHGRFEAQVQKNPHAIALVYEEQQMTFQEVNG 1737 + Q D + IH FE QV P+AIA+VYE QQ+T+ E+N Sbjct: 2618 LPLLTQPEQQKLLVEWNDTQVDYPEDLCIHQLFEEQVDSTPNAIAVVYENQQLTYYELNY 2677 Query: 1738 KANQLAWMLTGSGVQRNTPVGIFVDRSFSSVIGILAILKAGGAYVPLDPGYPEDRIAYIL 1797 +ANQLA L GV + VG+ V+RS VIG+L ILKAG AYVPLDP YP DR+++IL Sbjct: 2678 RANQLAHYLRSLGVGSDALVGLCVERSLEMVIGLLGILKAGAAYVPLDPEYPSDRLSFIL 2737 Query: 1798 AHSGAKWLLTENRYLQSVAAFAHEEGIQIINLSPVKEQSAVSQMYLADYEDELSRENPRT 1857 + LLT+ I++ P + V A + S++N + Sbjct: 2738 EDAQVSVLLTQQ---------------SILDRLPQHQAHLVCLDTDAQLISQCSQDNLIS 2782 Query: 1858 GGHGPDRMYIMYTSGSTGKPKGVLVTHSNVLNFVTWSIGELQLQPKDALLLVTSISFDIS 1917 + YI+YTSGSTG+PKG+ + + N + W L++ L SISFD+S Sbjct: 2783 DVQANNLAYIIYTSGSTGQPKGIAMNQLALSNLILWHRENLKIPRGAKTLQFASISFDVS 2842 Query: 1918 VFEIFAALLSGSRLCIASMEHLKDTECLLAYMEAQHITIWHSVPSLMVQLMTLLRHHPGR 1977 EIF SG L + E +DT LL +++ + ++ + + + L + Sbjct: 2843 FQEIFTTWCSGGTLFLIGEELRRDTSALLGFLQQK------AIERMFLPFVALQQLAEVA 2896 Query: 1978 YRHSPVLQQLRHLMLGGEAWSTSLAAS-LRETFPQAEIRNMYGPTEATIWVSSYKPGPEI 2036 V LR ++ GE + A S + N YGP+E+ + +S+ + Sbjct: 2897 IGGELVNSHLREIITAGEQLQITPAISQWLSKLTDCTLHNHYGPSESHL-ATSFTLTNSV 2955 Query: 2037 DESHPVM-LIGRPIANNRLIILDQYGNVCPPGVAGEIYIAGNNVTQGYYNDEEKTRMAFI 2095 E+ P++ +GRPIAN ++ ILD+Y P GV GE+YIAG ++QGY+N E T FI Sbjct: 2956 -ETWPLLPPVGRPIANAQIYILDKYLQPVPVGVPGELYIAGVLLSQGYFNRPELTLEKFI 3014 Query: 2096 PQ--------------------SNGQIF-----YKTGDSGRYLPEGNVEFTGRRDQLVKV 2130 P S G+ F YKTGD RYL +GN+E+ GR D VK+ Sbjct: 3015 PNPFKRSRGAALRLRSVTDEQGSRGETFNSDRLYKTGDLARYLSDGNIEYLGRIDNQVKI 3074 Query: 2131 RGYRIELGEIEQALKELTSLQQIAVTAVKDGETSKIVCLYTGDQPVPQNQ---------- 2180 RG+RIELGEIE L +L +Q A +D +K + Y VPQ + Sbjct: 3075 RGFRIELGEIEAVLSQL-DVQASCAIAREDIPGNKHLVAYI----VPQEEQTCTERSRST 3129 Query: 2181 -----LKDAVRKRLPEYMIPAQFFHVERFLLTPNGKMDWRSMEKFVRETPGSIEAAGIRN 2235 ++ ++++LPEYM+P+ ++ LTPNGK+D R++ + + RN Sbjct: 3130 LTVSFVRSFLKEKLPEYMVPSAIVILDALPLTPNGKLDRRALPAPDLHSQLLDKYVAPRN 3189 Query: 2236 EVDKKLSEIWKKLLGIPAVGIQENFFDIGGNSLLVVQMQGMIQQEFFQDIPMMDLFKYTS 2295 +++ LS IW ++L + VGI +NFF++GG+SLL Q+ ++ ++P+ LF + Sbjct: 3190 PIEEILSLIWAQVLKVEQVGIYDNFFELGGHSLLATQLISRVRTSLKVELPLRSLFAAPT 3249 Query: 2296 IEKISDYLQ 2304 + ++ +Q Sbjct: 3250 VAELCQNIQ 3258 Score = 569 bits (1466), Expect = e-160, Method: Compositional matrix adjust. Identities = 371/1205 (30%), Positives = 611/1205 (50%), Gaps = 92/1205 (7%) Query: 1171 IEQQIARIWGNLFQMPNIDIQDNFYELGGTSIMGIKIANRINEQYRVTMTIQDVFTHLTV 1230 IE+ ++ IW + ++ + I DNF+ELGG S++ ++ +R+ +V + ++ +F TV Sbjct: 3191 IEEILSLIWAQVLKVEQVGIYDNFFELGGHSLLATQLISRVRTSLKVELPLRSLFAAPTV 3250 Query: 1231 ASLGKLVEQKLGTKTEAGAVN-KQEVEYAKTSMPLSHAQRRIWFLQKMNPDLVAYNLPFI 1289 A L + +++ E A Q E A+ +PLS AQ R+WFL K+NP+ YN P Sbjct: 3251 AELCQNIQRLQQQDLELIASPILQRAENAE--LPLSFAQTRLWFLDKLNPNSAFYNFPIA 3308 Query: 1290 RYFDMAIDLELLQQAASFLAGRHLLMRTKYVLKDGNPVQEVLPAYVPAVQSI-------- 1341 ++ L+Q+ + RH +RT +V+ DG P Q ++ A + S+ Sbjct: 3309 LRLVGTLNRTALEQSLQEIVHRHEALRTNFVIVDGKPSQ-IIQAQINCTLSVVEFKHLST 3367 Query: 1342 ----DAAGQSDPELFV---KMNIHQQKMKPFNLEMPPY-RIYLYTISDERACLYINFHHI 1393 + G++ V + + Q +PF+L R L +S L + HHI Sbjct: 3368 LVLSEDVGEASASAEVTEQETALQQLAQQPFDLANEALVRATLIVLSQTEHTLLVCMHHI 3427 Query: 1394 LTDGWSIDIYYRELFSLYQAFLHQQPPRLPEVKEDYFDWILEQKAWEESEAFVEHEQFWL 1453 ++DGWS+ ++ +EL +LY A+ L + Y D+ + Q+ W + + +W Sbjct: 3428 VSDGWSMGVFVQELAALYNAYSQGDLSPLTPLPIQYADFAIWQRNWLQGDVLQSQLSYWQ 3487 Query: 1454 KELAKPLPVLSLPSDHKAPAVQTYRGSFHKFTISGELYRKLKAHLETQQITANNFLLSAY 1513 K+LA +LSLP+D P++QT+ G++ +F +S EL KL + Q +T LL+A+ Sbjct: 3488 KQLANAPALLSLPTDRPRPSMQTFAGAYQQFALSKELTDKLTQLSQQQGVTLFMTLLAAF 3547 Query: 1514 FLLLHNLSQEQDIIIGVPASGRNEQKWESVAGIFINTLCIRIHFQGITTFMELQDAVKHK 1573 LL+ + +DI++G P + R+ + E + G F+NTL +R + G +F EL V+ Sbjct: 3548 DTLLYRYTGTEDILVGSPIANRDRSEIEGLIGFFLNTLVMRTNLAGNPSFSELLGRVREM 3607 Query: 1574 VWSAMDKAQYPFDLLVEKVNPDRDLSRNPIYNVLFQFYD-----KLYLENEGISP----- 1623 A PF++LVE + P+RDLS P++ V+F + +L L +SP Sbjct: 3608 AMDAYSHQNLPFEMLVEALQPERDLSHTPLFQVMFVLQNAPISQQLELTGLTVSPLVVKS 3667 Query: 1624 ----FELSCLAQETNQQIEISFEYNSDMYTDSTISRFAGYFLNIIGQVVDKPXXXXXXXX 1679 F+L+ + T + +EYN+D++ STI R G+FL ++ ++ P Sbjct: 3668 TNTKFDLTLAMENTATGLVGMWEYNTDLFDASTIERMTGHFLTLLEGIIANPEERISQLP 3727 Query: 1680 XXXXXXXXXXXSRFQGEQADLEDGQTIHGRFEAQVQKNPHAIALVYEEQQMTFQEVNGKA 1739 + Q D IH FE QVQ+ P A+A+V+E+QQ+T+ ++N +A Sbjct: 3728 LLTEVEQHQLLVEWTDTQVDYPLDLCIHQLFEEQVQRTPDAVAVVFEDQQLTYHQLNSRA 3787 Query: 1740 NQLAWMLTGSGVQRNTPVGIFVDRSFSSVIGILAILKAGGAYVPLDPGYPEDRIAYILAH 1799 NQLA L GV+ + VGI V+RS V+G+L ILKAGGAY+PLDP YP +R+ ++L Sbjct: 3788 NQLAHYLKSLGVRADVLVGICVERSIEMVVGLLGILKAGGAYLPLDPEYPTERLHFMLED 3847 Query: 1800 SGAKWLLTENRYLQSVAAFAHEEGIQIINLSPVKEQSAVSQMYLADYEDELSRENPRTGG 1859 + LLT+ + L ++ H+ + ++ + +SQ S++N T Sbjct: 3848 AQVSVLLTQQKLLDRLS--QHQAKLVCLD----TDWQLISQS---------SQDNLITET 3892 Query: 1860 HGPDRMYIMYTSGSTGKPKGVLVTHSNVLNFVTWSIGELQLQPKDALLLVTSISFDISVF 1919 + Y++YTSGSTG+PKGVL+ H +LN V W ++ D + +FD +V+ Sbjct: 3893 QATNLAYVIYTSGSTGQPKGVLIAHQGLLNLVFWHQHTFKITTLDKATQLAGTAFDAAVW 3952 Query: 1920 EIFAALLSGSRLCIASMEHLKDTECLLAYMEAQHITIWHSVPSLMVQLMTLLRHHPGRYR 1979 E++ L +G+ + + E L L ++ ++ ITI L +L++L P Sbjct: 3953 ELWPYLTAGASIYLVKSEFLSSLVKLRDWLISKQITISFLPTPLAQELLSL--EWPTESL 4010 Query: 1980 HSPVLQQLRHLMLGGEAWSTSLAASLRETFPQAEIRNMYGPTEATIWVSS-YKPGPEIDE 2038 LR ++ GG+ L + P ++ N YGPTE T+ +S E D+ Sbjct: 4011 ------ALRTILTGGD----KLHQYPSDLVP-FQLVNNYGPTENTVVTTSGLVVAKEQDQ 4059 Query: 2039 SHPVMLIGRPIANNRLIILDQYGNVCPPGVAGEIYIAGNNVTQGYYNDEEKTRMAFI--P 2096 P IGR IAN ++ ILD P G+ GE++IAG + +GY N E T FI P Sbjct: 4060 ISPS--IGRAIANTQIYILDSNLQPVPIGIPGELHIAGVGLAKGYLNRPELTTEKFILNP 4117 Query: 2097 QSNG-QIFYKTGDSGRYLPEGNVEFTGRRDQLVKVRGYRIELGEIEQALKELTSLQQIAV 2155 G YKTGD RYLP+GN+E+ GR D VK+RG+RIEL EIE L + +Q V Sbjct: 4118 FDEGVSKLYKTGDLVRYLPDGNIEYLGRIDNQVKIRGFRIELAEIEALLGQHDDVQICCV 4177 Query: 2156 ---------TAVKDGETSKIV----------CLYTGDQPVPQNQLKDAVRKRLPEYMIPA 2196 T + + ++V C ++L+ + +LP YM+P+ Sbjct: 4178 IAREETSGNTCTERSRSKRLVAYVVPHLHATCTERSRSTPTTDELRQFLDDKLPGYMVPS 4237 Query: 2197 QFFHVERFLLTPNGKMDWRSM--EKFVRETPGSIEAAGIRNEVDKKLSEIWKKLLGIPAV 2254 F +E LTPNGK+D R++ +E + EV+K ++ IW+ L + V Sbjct: 4238 VFVMLESLPLTPNGKVDRRALPAPDLQQELSNYVMP---NTEVEKIIAGIWQNTLEVEKV 4294 Query: 2255 GIQENFFDIGGNSLLVVQMQGMIQQEFFQDIPMMDLFKYTSIEKISDYLQEHTVKVSSVE 2314 GI NFF++GG+SLL++++ +Q++F ++ ++D+F Y +I ++S YL K +++ Sbjct: 4295 GIYNNFFELGGHSLLLIRINQQLQEKFGLEVSIVDMFNYPTIHRLSQYLSTKLNKEDTLK 4354 Query: 2315 TGQKR 2319 R Sbjct: 4355 QNNSR 4359 Score = 533 bits (1374), Expect = e-149, Method: Compositional matrix adjust. Identities = 354/1128 (31%), Positives = 568/1128 (50%), Gaps = 108/1128 (9%) Query: 1259 KTSMPLSHAQRRIWFLQKMNPDLVAYNLPFIRYFDMAIDLELLQQAASFLAGRHLLMRTK 1318 KTS PLS Q +WF+ ++ P+ VAYN+ + +++ + + + RH ++RT Sbjct: 6 KTSFPLSSGQEAMWFIYQIAPESVAYNIFTTVKINSYLNIVAVNRVWEKIIERHPILRTT 65 Query: 1319 YVLKDGNPVQEVLPAYVPAVQSIDAAGQSDPELFVKMNIHQQKMKPFNLEMPP-YRIYLY 1377 Y +G PVQ+V Y V+ I+A+ S E ++K I PF LE RI L+ Sbjct: 66 YTNFEGKPVQQVNQQYKCNVEVINASNWS--EDYLKEKIFAITDSPFELEKDAVLRINLF 123 Query: 1378 TISDERACLYINFHHILTDGWSIDIYYRELFSLY--------QAFLHQQPPRLPEVKE-- 1427 T S + L + HHI D WS D+ E +LY Q + P E K Sbjct: 124 TRSTKEHILLLTMHHIAGDMWSFDLLLSEFQTLYAKEVEQVSQEQIQTAPDSFTENKSYL 183 Query: 1428 DYFDWILEQKAWEESEAFVEHEQFWLKELAKPLPVLSLPSDHKAPAVQTYRGSFHKFTIS 1487 D+ W E + E Q+W K+LA LP+L+L +D P VQTY+G+ + + Sbjct: 184 DFVRWQSEMLSGSRGEKLW---QYWQKQLAGELPILNLFADKPRPPVQTYQGTGYSLKLD 240 Query: 1488 GELYRKLKAHLETQQITANNFLLSAYFLLLHNLSQEQDIIIGVPASGRNEQKWESVAGIF 1547 +L +KLK + LL+A+++LL+ + + DI+IG P GR ++ + G F Sbjct: 241 EQLIQKLKCLALASGTSLYQVLLAAFYVLLYRYTNQTDILIGSPMRGRWGGDFKEIVGYF 300 Query: 1548 INTLCIRIHFQGITTFMELQDAVKHKVWSAMDKAQYPFDLLVEKVNPDRDLSRNPIYNVL 1607 +N + +R Q TF E + V A YPF LL E++ P+RD SR+P+ V Sbjct: 301 VNLMVLRTSVQENATFTEFLAHISKTVKEAQKHQDYPFSLLAEQLEPERDPSRSPLCQVS 360 Query: 1608 F---------QFYDKLYLENEGI------------SPFELSCLAQETNQQIEISFEYNSD 1646 F Q + L+ E + + + F+L+ + E +++ ++YN+D Sbjct: 361 FTWQRQRWCEQTENSLHSEEQVLEMKPYLLGHQRGADFDLNLMVMEAQGVLQLCWQYNTD 420 Query: 1647 MYTDSTISRFAGYFLNIIGQVVDKPXXXXXXXXXXXXXXXXXXXSRFQGEQADLEDGQTI 1706 ++ STI+R AG+F+ ++ +V P + D + I Sbjct: 421 LFEASTITRIAGHFVTLLEGIVANPQKQIWQLPLLTEIEQQQLLVEWNDTGVDYLQDKCI 480 Query: 1707 HGRFEAQVQKNPHAIALVYEEQQMTFQEVNGKANQLAWMLTGSGVQRNTPVGIFVDRSFS 1766 H FE QV++ P AIA+V+E QQ+T+Q++N +ANQLA L GV N VG+ V+RS Sbjct: 481 HQLFEEQVERTPDAIAVVFENQQLTYQQLNCRANQLAHYLQSLGVGENVLVGLCVERSLE 540 Query: 1767 SVIGILAILKAGGAYVPLDPGYPEDRIAYILAHSGAKWLLTENRYLQSVAAFAHEEGIQI 1826 V+G+L ILKAGGAYVPLDP YP +R++++L + K LLT+ + ++S+ H+ + Sbjct: 541 MVVGLLGILKAGGAYVPLDPEYPAERLSFMLKDTQVKVLLTQEKLVESLP--QHQACVVC 598 Query: 1827 INLSPVKEQSAVSQMYLADYEDELSRENPRTGGHGPDRMYIMYTSGSTGKPKGVLVTHSN 1886 ++ + ++SQ+ + + +S EN Y++YTSGSTG PKGV VTH Sbjct: 599 LD----TDWQSISQVNQDNLDSTVSAEN---------LSYVIYTSGSTGTPKGVAVTHQA 645 Query: 1887 VLNFVTWSIGELQLQPKDALLLVTSISFDISVFEIFAALLSGSRLCIASMEHLKDTECLL 1946 V N + + +QL + + +I+FD + FEI+ ALL G++L I + L E Sbjct: 646 V-NRLMLNTNYIQLTADECVAQAANIAFDAATFEIWGALLHGAKLVIITKFVLLIPEEFA 704 Query: 1947 AYMEAQHITIWHSVPSLMVQLMTLLRHHPGRYRHSPVLQQLRHLMLGGEAWSTSLAASLR 2006 + I++ +L QL +++ LR+L+ GGEA + Sbjct: 705 VNIHEHQISVLFLTTALFNQLASVVPQ---------AFSSLRYLLFGGEAVDPKWVLEVL 755 Query: 2007 ETFPQAEIRNMYGPTEATIWVSSYKPGPEIDESHPVMLIGRPIANNRLIILDQYGNVCPP 2066 + + ++YGPTE T + SS+ ++ + + IGR IAN ++ ILDQ P Sbjct: 756 DKGAPQHLLHVYGPTENTTF-SSWYLVEDLATTATTIPIGRAIANTQIYILDQNLQPVPV 814 Query: 2067 GVAGEIYIAGNNVTQGYYNDEEKTRMAFIPQS-NGQIFYKTGDSGRYLPEGNVEFTGRRD 2125 GV GEIY+ G + QGY+N E T+ FIP + YKTGD YL +GN+E+ GR D Sbjct: 815 GVPGEIYLGGAGLAQGYFNRPELTKDKFIPNPFDNSKLYKTGDLAHYLADGNIEYLGRID 874 Query: 2126 QLVKVRGYRIELGEIEQALKELTSLQQIAVTAVKD--GETSK------------------ 2165 VK+RG+RIEL EIE L + + +Q V +D G+T Sbjct: 875 NQVKIRGFRIELSEIEVVLSQHSDVQVSCVIVREDTPGDTCTERLVPSGAEVSRSKRLVA 934 Query: 2166 IVCLYTGDQPVPQNQLKDAVRKRLPEYMIPAQFFHVERFLLTPNGKMDWRSM-------- 2217 V Y +P ++L+ + +LP+YM+P +E LTPNGK+D R++ Sbjct: 935 YVVAYQDCKPTI-SELRQFLTAKLPDYMVPNAIVILESLPLTPNGKVDRRALPIPDLHSE 993 Query: 2218 --EKFVRETPGSIEAAGIRNEVDKKLSEIWKKLLGIPAVGIQENFFDIGGNSLLVVQMQG 2275 EKFV RN +++ L+ +W ++L + +GI +NFF++GG+SLL Q+ Sbjct: 994 QQEKFV----------APRNPMEEMLALLWTQVLKVELLGIHDNFFELGGHSLLATQLVS 1043 Query: 2276 MIQQEFFQDIPMMDLFKYTSIEKISD---YLQEHTVKVSSVETGQKRA 2320 I+ F ++P+ +LF ++ +++ LQ+ ++++S G R+ Sbjct: 1044 RIRNVFKLELPLRELFARATVAELAKSIRQLQQQALRLTSAPLGTSRS 1091 >gb|AAO23333.1| NcpA [Nostoc sp. ATCC 53789] Length = 3735 Score = 629 bits (1621), Expect = e-178, Method: Compositional matrix adjust. Identities = 395/1214 (32%), Positives = 630/1214 (51%), Gaps = 79/1214 (6%) Query: 1132 FWNRPLPVSLAP---AIREQIK-HPEAEIDVRL----TGRADQSY----TEIEQQIARIW 1179 F LP + P AI E + P +ID R T + Y T IE+ +A IW Sbjct: 992 FLKEKLPEYMVPSAIAILESLPLTPNGKIDRRALPEPTSELSEKYVAPRTPIEEILAVIW 1051 Query: 1180 GNLFQMPNIDIQDNFYELGGTSIMGIKIANRINEQYRVTMTIQDVFTHLTVASLGKLVEQ 1239 + ++ + DNF+ELGG S++ + +R+ + +V ++++++F T+A L ++Q Sbjct: 1052 QQVLKLELVGRHDNFFELGGHSLLATQFISRVRSRLKVEISLRELFAAPTIAELAPSIQQ 1111 Query: 1240 KLGTKTEAGAVN-KQEVEYAKTSMPLSHAQRRIWFLQKMNPDLVAYNLPFIRYFDMAIDL 1298 E A + VE +PLS+AQ+R+WFL ++ + YN+ + Sbjct: 1112 LQQQNIELSAPPILRRVE--NIEIPLSYAQQRLWFLNQLESNSALYNIALGLRLVGTFNF 1169 Query: 1299 ELLQQAASFLAGRHLLMRTKYVLKDGNPVQ--EVLPAYVPAVQSIDAAGQSDPELFVKMN 1356 L+Q+ L RH ++RT +V DG P Q + + AV + ++ + + Sbjct: 1170 AALEQSLKELIDRHEVLRTNFVTVDGKPTQIIQTQTNWTVAVVDLQHLPLTEQQTAAQKL 1229 Query: 1357 IHQQKMKPFNLEMPPY-RIYLYTISDERACLYINFHHILTDGWSIDIYYRELFSLYQAF- 1414 + Q+ ++PF+L R L +S + CL ++ HH++ DGWSI ++ +EL +LY A+ Sbjct: 1230 LEQKAIEPFDLAHDALIRATLVMLSPKEQCLLVSMHHVVCDGWSIGVFVQELQALYNAYS 1289 Query: 1415 LHQQPPRLPEVKEDYFDWILEQKAWEESEAFVEHEQFWLKELAKPLPVLSLPSDHKAPAV 1474 + Q P LP + Y D+ + Q+ W + E H +W K+LA L LP+D PAV Sbjct: 1290 IGQASPLLP-LPIQYADFAIWQRQWLQGEVLQNHLSYWEKQLANAPTFLPLPTDRPRPAV 1348 Query: 1475 QTYRGSFHKFTISGELYRKLKAHLETQQITANNFLLSAYFLLLHNLSQEQDIIIGVPASG 1534 QT+ GS+H FT+S EL ++L + Q T LL+ Y LL+ + + DI++G P + Sbjct: 1349 QTFNGSYHVFTLSVELTQRLLELSQQQGCTLFMTLLAVYNTLLYRYTGQSDILVGTPIAN 1408 Query: 1535 RNEQKWESVAGIFINTLCIRIHFQGITTFMELQDAVKHKVWSAMDKAQYPFDLLVEKVNP 1594 R+ + E + G F+NTL +R G +F EL ++ SA PF++LVE + P Sbjct: 1409 RDRTELERLIGFFVNTLVMRTDLAGNPSFNELLLRLREMALSAYAHQDLPFEMLVEALEP 1468 Query: 1595 DRDLSRNPIYNVLFQFYDKLYLENE-------------GISPFELSCLAQETNQQIEISF 1641 +RDLS P++ V+F + E E S F+L+ + T + + Sbjct: 1469 ERDLSYTPLFQVMFVLLNAPMSEIELTELSVSGLPIEITTSKFDLTLSMENTPNGLFGWW 1528 Query: 1642 EYNSDMYTDSTISRFAGYFLNIIGQVVDKPXXXXXXXXXXXXXXXXXXXSRFQGEQADLE 1701 EYN+D++ STI R G+FL ++ +V P + Q D Sbjct: 1529 EYNTDLFDSSTIERMTGHFLTLLEAIVANPSERISQLPMLTASEQQQLLVEWNDTQVDYP 1588 Query: 1702 DGQTIHGRFEAQVQKNPHAIALVYEEQQMTFQEVNGKANQLAWMLTGSGVQRNTPVGIFV 1761 + IH FE QV++ P+A+A+V+E QQ+T+ E+N +ANQLA L GV + VGI V Sbjct: 1589 HDKCIHQLFEEQVERTPNAVAVVFENQQLTYHELNCRANQLAHYLRSLGVGADILVGICV 1648 Query: 1762 DRSFSSVIGILAILKAGGAYVPLDPGYPEDRIAYILAHSGAKWLLTENRYLQSVAAFAHE 1821 +RS ++G+L ILKAGGAYVPLDP YP++R+++IL + LLT+ Sbjct: 1649 ERSLEMLVGLLGILKAGGAYVPLDPEYPQERLSFILEDAQVSVLLTQQ------------ 1696 Query: 1822 EGIQIINLSPVKEQSAVSQMYLADYEDELSRENPRTGGHGPDRMYIMYTSGSTGKPKGVL 1881 +++ P + VS + +L + NP T + Y++YTSGSTG+PKGV Sbjct: 1697 ---HLVDKLPECQAQLVSLDTNWQFISQLPQGNPITNVQASNLTYVIYTSGSTGQPKGVQ 1753 Query: 1882 VTHSNVLNFVTWSIGELQLQPKDALLLVTSISFDISVFEIFAALLSGSRLCIASMEHLKD 1941 ++H+ V NF++ + +D LL VT+ISFDI+ EIF + G+ L IA + D Sbjct: 1754 ISHTAVSNFLSAMQQRPGITEQDTLLAVTTISFDIAALEIFLPITVGACLVIARRDVTLD 1813 Query: 1942 TECLLAYMEAQHITIWHSVPSLMVQLMTLLRHHPGRYRHSPVLQQLRHLMLGGEAWSTSL 2001 L + TI + P+ L+ Y+ S + ++ GGEA L Sbjct: 1814 GRELCDLLVKSKATIMQATPATWRLLLD------SNYQFSDL-----KILCGGEALPWDL 1862 Query: 2002 AASLRETFPQAEIRNMYGPTEATIWVSSYKPGPEIDESHPVMLIGRPIANNRLIILDQYG 2061 + L A + N+YGPTEATIW S +++ S ++ IGRPI+N ++ ILDQ Sbjct: 1863 VSKLLAR--SASLWNLYGPTEATIWSSIC----QLESSESLISIGRPISNTQIYILDQNL 1916 Query: 2062 NVCPPGVAGEIYIAGNNVTQGYYNDEEKTRMAFIP-----------QSNGQIFYKTGDSG 2110 P GV GE++I G + +GY E T+ FIP ++ G YKTGD Sbjct: 1917 QPVPIGVPGELHIGGAGLARGYLKRPELTQEKFIPNPFEEAGGRGQEAGGSRLYKTGDLA 1976 Query: 2111 RYLPEGNVEFTGRRDQLVKVRGYRIELGEIEQALKELTSLQQIAVTAVKDGETSKIVCLY 2170 RYLP+GN+E+ GR D VK+RG+RIELGEIE AL + +Q V A +D K + Y Sbjct: 1977 RYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAALSQHPHVQASCVIAREDTPGDKRLVAY 2036 Query: 2171 TGDQP---VPQNQLKDAVRKRLPEYMIPAQFFHVERFLLTPNGKMDWRSMEKFVRETPGS 2227 QP + ++L+ ++++LP+YM+P+ +E LTPNGK+D R++ + Sbjct: 2037 IVPQPQVTLTISELRSNLKEKLPDYMVPSAIVILESLPLTPNGKIDRRALPAPEPSSELL 2096 Query: 2228 IEAAGIRNEVDKKLSEIWKKLLGIPAVGIQENFFDIGGNSLLVVQMQGMIQQEFFQDIPM 2287 + RN +++ LS IW+++L + VG +NFF++GG+SLL Q+ ++ ++P+ Sbjct: 2097 EKYVAPRNPIEEILSLIWQQVLKVDLVGRHDNFFELGGHSLLATQLISRVRSSLKVELPL 2156 Query: 2288 MDLFKYTSIEKISD 2301 LF +I ++S+ Sbjct: 2157 RSLFAAPTIAELSN 2170 Score = 609 bits (1570), Expect = e-172, Method: Compositional matrix adjust. Identities = 377/1152 (32%), Positives = 611/1152 (53%), Gaps = 81/1152 (7%) Query: 1171 IEQQIARIWGNLFQMPNIDIQDNFYELGGTSIMGIKIANRINEQYRVTMTIQDVFTHLTV 1230 IE+ ++ IW + ++ + DNF+ELGG S++ ++ +R+ +V + ++ +F T+ Sbjct: 2106 IEEILSLIWQQVLKVDLVGRHDNFFELGGHSLLATQLISRVRSSLKVELPLRSLFAAPTI 2165 Query: 1231 ASLGK-LVEQKLGTKTEAGAVNKQEVEYAKTSMPLSHAQRRIWFLQKMNPDLVAYNLPFI 1289 A L + + + A A + E A+T PLS+AQ+R+WFL + P+ +YN+PF Sbjct: 2166 AELSNNIQQLQQQDLELAAAPILRRAENAET--PLSYAQQRLWFLDQFEPNSASYNIPFG 2223 Query: 1290 RYFDMAIDLELLQQAASFLAGRHLLMRTKYVLKDG---------------NPVQEVLPAY 1334 +++ L+Q+ + RH +RT ++ DG N QE +P + Sbjct: 2224 LRLVGTLNVVALEQSLIEIIHRHEALRTNFITVDGQATQIIHNWKEQGTGNREQENIP-W 2282 Query: 1335 VPAVQSIDAAGQSDPELFVKMNIHQQKMKPFNLEMPPY-RIYLYTISDERACLYINFHHI 1393 +V + ++ + + + +Q PF+L R L +S L + HH+ Sbjct: 2283 TLSVVDLKHLPLTEQKTAAQKLVQEQAFLPFDLAHDALIRATLIVLSPTEQWLLVCMHHV 2342 Query: 1394 LTDGWSIDIYYRELFSLYQAFLHQQPPRLPEVKEDYFDWILEQKAWEESEAFVEHEQFWL 1453 ++DGWSI ++ +EL +LY A+ QP L + Y D+ + Q+ W + E +W Sbjct: 2343 VSDGWSIGVFSQELQALYNAYSQGQPSPLLPLPIQYADFAIWQRQWLQGEVLQSQLSYWK 2402 Query: 1454 KELAKPLPVLSLPSDHKAPAVQTYRGSFHKFTISGELYRKLKAHLETQQITANNFLLSAY 1513 ++LA L LP+D PA+QT+ G++ +F +S EL ++L + Q +T LL+AY Sbjct: 2403 QQLANAPTFLPLPTDRPRPAIQTFNGAYQEFALSSELTQRLVQLSQKQGVTLFMTLLAAY 2462 Query: 1514 FLLLHNLSQEQDIIIGVPASGRNEQKWESVAGIFINTLCIRIHFQGITTFMELQDAVKHK 1573 LL+ + + DI++G P + R+ + E + G F+NTL +R +F EL ++ Sbjct: 2463 NTLLYRYTGQTDILVGTPIANRDRTEIEGLIGFFVNTLVMRTDLSLNPSFNELLPRIREM 2522 Query: 1574 VWSAMDKAQYPFDLLVEKVNPDRDLSRNPIYNVLFQFYDKLYLENE-------------G 1620 SA PF++LVE + P+RDLS P++ V+F + E E Sbjct: 2523 ALSAYAHQDLPFEMLVEALQPERDLSYTPLFQVMFVLNNAPTSEVELTGLSISSLPIESA 2582 Query: 1621 ISPFELSCLAQETNQQIEISFEYNSDMYTDSTISRFAGYFLNIIGQVVDKPXXXXXXXXX 1680 I+ F+L+ + T+ + +EYN D++ +TI R G+F+ ++ +V P Sbjct: 2583 IAKFDLTLSMENTSTGLVGGWEYNIDLFDSNTIERITGHFVTLLEAIVANPQERISQLPM 2642 Query: 1681 XXXXXXXXXXSRFQGEQADLEDGQTIHGRFEAQVQKNPHAIALVYEEQQMTFQEVNGKAN 1740 + D + IH FE QV++ P A+A+V+E QQ+T+ ++N +AN Sbjct: 2643 LTAFEQQQLLVEWNDTSVDYPQDKCIHQLFEEQVERIPDAVAVVFENQQLTYHQLNCRAN 2702 Query: 1741 QLAWMLTGSGVQRNTPVGIFVDRSFSSVIGILAILKAGGAYVPLDPGYPEDRIAYILAHS 1800 LA L GV + VGI V+RS V+G+L ILKAGGAYVPLDP YP++R+ ++LA + Sbjct: 2703 HLAHYLQSLGVSADVLVGICVERSLEMVVGLLGILKAGGAYVPLDPEYPQERLTFMLADA 2762 Query: 1801 GAKWLLTENRYLQSVAAFAHEEGIQIINLSPVKEQSAVSQMYLADYEDELSRENPRTGGH 1860 LLT+ ++ + H+ ++++L K+ A+++ S+ENP Sbjct: 2763 QVSVLLTQQHLVEKLP--RHQA--RVVHLD--KDWVAIAKS---------SQENPIAQVQ 2807 Query: 1861 GPDRMYIMYTSGSTGKPKGVLVTHSNVLNFVTWSIGELQLQPKDALLLVTSISFDISVFE 1920 + Y++YTSGSTG+PKGV+++HSN+ N + W L +D +L T FD SV+E Sbjct: 2808 ASNVAYVIYTSGSTGQPKGVILSHSNLCNHMFWMQATFPLTKEDKVLQKTPFGFDASVWE 2867 Query: 1921 IFAALLSGSRLCIASMEHLKDTECLLAYMEAQHITIWHSVPSLMVQLMTLLRHHPGRYRH 1980 +A LL+G +L IA D+ LL + Q +T VPSL L LL H Sbjct: 2868 FYAPLLAGGQLLIAEPRGHTDSAYLLRLIAQQQVTTIQLVPSL---LQMLLEQGGIETCH 2924 Query: 1981 SPVLQQLRHLMLGGEAWSTSLAASLRETFPQAEIRNMYGPTEATIWVSSYKPGPEIDESH 2040 S L+H+ GGE +L SL + N+YGPTEA I + + EI + Sbjct: 2925 S-----LKHVFCGGEVLPVTLQESLLSKL-DVNLHNLYGPTEACIDATFWNCQREI---Y 2975 Query: 2041 PVML-IGRPIANNRLIILDQYGNVCPPGVAGEIYIAGNNVTQGYYNDEEKTRMAFIPQ-- 2097 P ++ IGRPI N ++ ILDQ P GV GE++I G + +GY N E T+ FIP Sbjct: 2976 PQLIPIGRPIDNTQIYILDQNLQPVPVGVPGELHIGGAGLAKGYLNLPELTQEKFIPNPF 3035 Query: 2098 --SNG---------QIFYKTGDSGRYLPEGNVEFTGRRDQLVKVRGYRIELGEIEQALKE 2146 S G + YKTGD RYLP+GN+E+ GR D VK+RG+RIELGEIE AL + Sbjct: 3036 QGSRGAGEQGSRGRERLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAALSQ 3095 Query: 2147 LTSLQQIAVTAVKDGETSKIVCLYTGDQP--VPQ-NQLKDAVRKRLPEYMIPAQFFHVER 2203 + +Q V +D +K + Y QP P +QL+ ++++LPEYM+P+ +E Sbjct: 3096 HSDVQTSVVIVREDIPGNKRLVAYVVPQPQITPTVSQLRSFLKEKLPEYMVPSAIVTLES 3155 Query: 2204 FLLTPNGKMDWRSMEKFVRETPGSIEAAGI--RNEVDKKLSEIWKKLLGIPAVGIQENFF 2261 LTPNGK+D R++ + E IE++ + R +++KL+ IW+++L + +GI +NFF Sbjct: 3156 LPLTPNGKIDRRALPE--PEARTGIESSLVAPRTPIEEKLTRIWEQVLRVEQIGIHDNFF 3213 Query: 2262 DIGGNSLLVVQM 2273 ++GG+S+L +Q+ Sbjct: 3214 ELGGDSILSIQI 3225 Score = 503 bits (1296), Expect = e-140, Method: Compositional matrix adjust. Identities = 354/1096 (32%), Positives = 552/1096 (50%), Gaps = 96/1096 (8%) Query: 1261 SMPLSHAQRRIWFLQKMNPDLVAYNLPFIRYFDMAIDLELLQQAASFLAGRHLLMRTKYV 1320 + PLSH Q+ +WFL ++ + AYN+ + +++D+ L+QAA L RH L+RT + Sbjct: 61 TYPLSHGQKALWFLYQLARNSTAYNVTYAAKLVISLDILALKQAAQALVERHPLLRTTFA 120 Query: 1321 LKDGNPVQEVLPAYVP--AVQSIDAAGQSDPELFVKMNIHQQKMKPFNLEMPPY------ 1372 D PVQ V ++Q GQ D + + ++ +PF+LE P Sbjct: 121 TIDDEPVQTVHENQQVDFSIQEASDLGQDD----INNWLSEKSDRPFDLEQGPILRFDLL 176 Query: 1373 --RIYLYTISDERACLYINFHHILTDGWSIDIYYRELFSLYQA-------FLHQQPPRLP 1423 I ++ + L I H I+ D S++I EL +LY+A + + +L Sbjct: 177 INHIKTDKLATKEHILLITLHQIVGDFRSLEIIIGELRALYKAMSTTGYAYATGETAQLS 236 Query: 1424 EVKEDYFDWILEQKAWEESEAFVEHEQ---FWLKELAKPLPVLSLPSDHKAPAVQTYRGS 1480 Y D++ K E+ A E +W ++L+ LP+L+LP+D P +TY G+ Sbjct: 237 TQNYQYQDYV---KCSEQMLASSHGESLWAYWQQQLSGELPLLNLPTDRPRPQTKTYNGA 293 Query: 1481 FHKFTISGELYRKLKAHLETQQITANNFLLSAYFLLLHNLSQEQDIIIGVPASGRNEQKW 1540 FT+ EL +KL + + LL+A +LL + ++DI+IG P R+ ++ Sbjct: 294 SRFFTVEKELRQKLTELATRESASLYILLLTALQILLRRYTNQEDILIGSPMVNRSRSEF 353 Query: 1541 ESVAGIFINTLCIRIHFQGITTFMELQDAVKHKVWSAMDKAQYPFDLLVEKVNPDRDLSR 1600 ES+ G F N + +R G TF E+ + V A D YPF LLVE++ P R+ S Sbjct: 354 ESIVGHFTNPVVLRGDLSGNPTFEEMLERSHSCVLDAQDHQDYPFSLLVEQLQPVRNPSF 413 Query: 1601 NPIYNVLF---------QFYDKLYLEN----EGISPFELSCLAQETNQQIEISFEYNSDM 1647 +P+Y V F D L LE+ + F+L+ E ++ ++ YN+D+ Sbjct: 414 SPLYQVAFVCDRSHQNIDINDDLILESMIPESKGAAFDLTLTIFEGTDSLKGTWNYNTDL 473 Query: 1648 YTDSTISRFAGYFLNIIGQVVDKPXXXXXXXXXXXXXXXXXXXSRFQGEQADLEDGQTIH 1707 + DS I+R G+F+ ++ +V P + Q D + IH Sbjct: 474 FDDSAIARMMGHFVTLLEAIVANPQQRIDQLPMLTQSEERQLLVEWNDTQVDYAFDKCIH 533 Query: 1708 GRFEAQVQKNPHAIALVYEEQQMTFQEVNGKANQLAWMLTGSGVQRNTPVGIFVDRSFSS 1767 FE QV++ P A+A+V+E QQ+T++E+N +ANQLA+ L GV+ + VGI V+RS Sbjct: 534 QLFEEQVKRTPDAVAVVFENQQLTYRELNSRANQLAYCLQSLGVKPDVLVGICVERSLEM 593 Query: 1768 VIGILAILKAGGAYVPLDPGYPEDRIAYILAHSGAKWLLTENRYLQSVAAFAHEEGIQII 1827 V+G+L ILKAGGAYVPLDP YP+DR+ ++LA + L+++ R L + + ++I Sbjct: 594 VVGLLGILKAGGAYVPLDPEYPKDRLNFMLADAQVPVLISQQRLLDRLPEYQA----KLI 649 Query: 1828 NLSPVKEQSAVSQMYLADYEDELSRENPRTGGHGPDRMYIMYTSGSTGKPKGVLVTHSNV 1887 L V + ++ + NP D ++YTSGSTGKPKGV+V HS + Sbjct: 650 CLDEVWSEILQNK-----------QNNPIEVVKSTDLANVIYTSGSTGKPKGVMVEHSGL 698 Query: 1888 LNFVTWSIGELQLQPKDALLLVTSISFDISVFEIFAALLSGSRLCIASMEHLKDTECLLA 1947 N I L +L S SFD + EI AL SG+RL + + + + L+ Sbjct: 699 CNLAQAQIQVFGLSGDSRVLQFASFSFDACISEILMALGSGARLYLGTKDSIMPGMPLIE 758 Query: 1948 YMEAQHITIWHSVPSLMVQLMTLLRHHPGRYRHSPV--LQQLRHLMLGGEAWSTSLAASL 2005 ++ IT PS + L PV L L+ +++ GEA L + Sbjct: 759 RLKNDGITHVTLPPSALAVL--------------PVEELPTLQAIVVAGEACPLEL---M 801 Query: 2006 RETFPQAEIRNMYGPTEATIWVSSYKPGPEIDESHPVMLIGRPIANNRLIILDQYGNVCP 2065 R+ N YGPTEA++ + K PE DE + IGRPIAN + ILD P Sbjct: 802 RQWSKGRNFFNAYGPTEASVCAAIAKCTPE-DEK---ITIGRPIANAEIYILDSQLQPVP 857 Query: 2066 PGVAGEIYIAGNNVTQGYYNDEEKTRMAFIP----QSNG---------QIFYKTGDSGRY 2112 GV GE++I G V +GY N E T+ FIP +S G + YKTGD RY Sbjct: 858 IGVPGELHIGGAGVARGYLNRNELTQQKFIPNPFSRSRGAGEQGSRGRERLYKTGDLARY 917 Query: 2113 LPEGNVEFTGRRDQLVKVRGYRIELGEIEQALKELTSLQQIAVTAVKDGETSKIVCLYTG 2172 LP+GN+E+ GR D VK+RG+RIELGEIE L + +Q V A +D K + Y Sbjct: 918 LPDGNIEYLGRIDNQVKIRGFRIELGEIEATLSQHPHVQASCVIAREDIPGDKRLIAYIV 977 Query: 2173 DQP---VPQNQLKDAVRKRLPEYMIPAQFFHVERFLLTPNGKMDWRSMEKFVRETPGSIE 2229 QP +L+ ++++LPEYM+P+ +E LTPNGK+D R++ + E S + Sbjct: 978 LQPEQTATVKELRSFLKEKLPEYMVPSAIAILESLPLTPNGKIDRRALPEPTSEL--SEK 1035 Query: 2230 AAGIRNEVDKKLSEIWKKLLGIPAVGIQENFFDIGGNSLLVVQMQGMIQQEFFQDIPMMD 2289 R +++ L+ IW+++L + VG +NFF++GG+SLL Q ++ +I + + Sbjct: 1036 YVAPRTPIEEILAVIWQQVLKLELVGRHDNFFELGGHSLLATQFISRVRSRLKVEISLRE 1095 Query: 2290 LFKYTSIEKISDYLQE 2305 LF +I +++ +Q+ Sbjct: 1096 LFAAPTIAELAPSIQQ 1111 Score = 102 bits (253), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 97/407 (23%), Positives = 174/407 (42%), Gaps = 41/407 (10%) Query: 1146 REQIKHPEAEIDVRLTGRADQSYTEIEQQIARIWGNLFQMPNIDIQDNFYELGGTSIMGI 1205 R + PEA + + A + T IE+++ RIW + ++ I I DNF+ELGG SI+ I Sbjct: 3166 RRALPEPEARTGIESSLVAPR--TPIEEKLTRIWEQVLRVEQIGIHDNFFELGGDSILSI 3223 Query: 1206 KIANRINEQYRVTMTIQDVFTHLTVASLGKLVEQKLGTKTEAGAVNKQEVEYAKTSMPLS 1265 +I +R + + +TI+ +F + T+A L + E G V ++PL+ Sbjct: 3224 QIISR-AKVAGIELTIKQLFANQTIAQLATVAGTTKALAIEQGLVTG--------TLPLT 3274 Query: 1266 HAQRRIWFLQKMNPDLVAYNLPFIRYFDMAIDLELLQQAASFLAGRHLLMRTKYVLKD-- 1323 Q WF ++ P+ +N F+ ++LE+L+Q L H +R ++ D Sbjct: 3275 PIQH--WFFEQKLPEKHHFNQSFLLTVPSDLNLEILEQVWQQLLKHHDALRLRFTRTDTI 3332 Query: 1324 -----GNPVQEV-LPAY----VPAVQSIDAAGQSDPELFVKMNIHQQKMKPFNLEMPPYR 1373 P + +P + VP + + EL +N+ + ++ Sbjct: 3333 WQQIHAAPTDNITIPRFDLSTVPETEIETVIETTANELQASLNLSENLVQ---------V 3383 Query: 1374 IYLYTISDERACLYINFHHILTDGWSIDIYYRELFSLYQAFLHQQPPRLPEVKEDYFDWI 1433 + + D++A L I HH++ DG S I +L + YQ + +LP + DW Sbjct: 3384 AFFWLGIDKKARLIIVIHHLVVDGVSWRILLEDLQTAYQQLSQGKTIQLPAKTTSFKDWA 3443 Query: 1434 LEQKAWEESEAFVEHEQFWLKELAKPLPVLSLPSDHKAPAVQTYRGSFHKFTIS---GEL 1490 + + +SE +WL V S+P D+ A + T S ++S E Sbjct: 3444 RQLTEYAQSEVLKSELDYWLSPSYD--TVDSIPVDY-AQGINT-TASARTISVSLDEAET 3499 Query: 1491 YRKLKAHLETQQITANNFLLSAYFLLLHNLSQEQDIIIGVPASGRNE 1537 L+ + + N+ LL+A L+L + ++ + GR E Sbjct: 3500 LSLLQDVPKAYKTQINDILLTALVLVLSEWTNSDSVLFNLEGHGREE 3546 >ref|ZP_00177151.1| hypothetical protein Cwat285401 [Crocosphaera watsonii WH 8501] Length = 6281 Score = 619 bits (1595), Expect = e-175, Method: Compositional matrix adjust. Identities = 375/1132 (33%), Positives = 607/1132 (53%), Gaps = 57/1132 (5%) Query: 1169 TEIEQQIARIWGNLFQMPNIDIQDNFYELGGTSIMGIKIANRINEQYRVTMTIQDVFTHL 1228 T IE+ +A IW + + + + +NF+ELGG S++ ++ ++I + + V + ++ +F Sbjct: 1918 TPIEELLADIWTEILGIETVGVNNNFFELGGHSLIATRVVSQIRQVFNVELPLRSLFEKP 1977 Query: 1229 TVASLGKLVEQKLGTKTEAGAVNKQEVEYAKTSMPLSHAQRRIWFLQKMNPDLVAYNLPF 1288 T+A L K +E+ + + E V+ + V + +PLS AQ+R+WFL ++ PD YN+ Sbjct: 1978 TIAELAKEIEKVINSDVEVEFVSIERVSRNR-ELPLSFAQQRLWFLAELEPDSPFYNISG 2036 Query: 1289 IRYFDMAIDLELLQQAASFLAGRHLLMRTKYVLKDGNPVQEVLPAYVPAVQSIDAAG--Q 1346 +++E L+Q+ + + RH +RT + +DG V + P + ++D + Sbjct: 2037 AVKLQGQLNVEALEQSFNEIVRRHENLRTNFQTRDGQAVAVISPERPLNLSTVDISSLNG 2096 Query: 1347 SDPELFVKMNIHQQKMKPFNLEM-PPYRIYLYTISDERACLYINFHHILTDGWSIDIYYR 1405 S E V+ I ++ KPF++ RI L + +E + + HHI++DGWS+ ++ + Sbjct: 2097 STQEEKVRQEITKEAEKPFDISKDLLLRIKLLHLGEEENIVLVTMHHIISDGWSMGVFIK 2156 Query: 1406 ELFSLYQAFLHQQPPRLPEVKEDYFDWILEQKAWEESEAFVEHEQFWLKELAKPLPVLSL 1465 EL +LY F +Q+P L E+ Y D+ Q+ W + E +WLK+L +L L Sbjct: 2157 ELGTLYTNFCNQEPISLQELPIQYVDFAAWQREWLQGEVLENQVSYWLKQLENTPKLLEL 2216 Query: 1466 PSDHKAPAVQTYRGSFHKFTISGELYRKLKAHLETQQITANNFLLSAYFLLLHNLSQEQD 1525 P++ PA+QT+ G+ H F +S EL L + + T LL+ + LL + ++D Sbjct: 2217 PTNKPRPAIQTFNGATHSFELSKELSLALNKLSQQKGSTLFMTLLAGFQTLLWRYTAQED 2276 Query: 1526 IIIGVPASGRNEQKWESVAGIFINTLCIRIHFQGITTFMELQDAVKHKVWSAMDKAQYPF 1585 +++G P + RN + E + G F+NTL +R + +F EL + V+ A PF Sbjct: 2277 VVVGSPIANRNRGEIEGLIGFFVNTLVLRTNLAENPSFSELLEQVREVTLGAYSHQDVPF 2336 Query: 1586 DLLVEKVNPDRDLSRNPIYNVLFQFYDK------------LYLENE-GISPFELSCLAQE 1632 +LLVE++ P+RDLS +P++ V+F + LEN+ + F+LS E Sbjct: 2337 ELLVERLQPERDLSHSPLFQVMFVLQNAPMSALELPGVTLTSLENKHQTAKFDLSLYMTE 2396 Query: 1633 TNQQIEISFEYNSDMYTDSTISRFAGYFLNIIGQVVDKPXXXXXXXXXXXXXXXXXXXSR 1692 T + +FEYN+D++ + TI+R G+ ++ +V P Sbjct: 2397 TESGLVGNFEYNTDLFEEKTITRMVGHLERLLSAIVANPQQPLSDLPLLSEPERHQLLWE 2456 Query: 1693 FQGEQADLEDGQTIHGRFEAQVQKNPHAIALVYEEQQMTFQEVNGKANQLAWMLTGSGVQ 1752 + + + Q IH FEAQV+K P A+A+ +E Q++T+QE+N KANQ+A L GV+ Sbjct: 2457 WNQTKVEYPQNQCIHQLFEAQVEKTPEAVAVEFEGQKLTYQELNKKANQVAHYLRSLGVK 2516 Query: 1753 RNTPVGIFVDRSFSSVIGILAILKAGGAYVPLDPGYPEDRIAYILAHSGAKWLLTENRYL 1812 VGI+++RS VIG+L ILKAGGAYVPL+P YP +RI Y+L S LLT N + Sbjct: 2517 PEVLVGIYIERSLEMVIGLLGILKAGGAYVPLEPTYPTERIQYLLEDSKVAILLTRNHLI 2576 Query: 1813 QSVAAFAHEEGIQIINLSPVKEQSAVSQMYLADYEDELSRENPRTGGHGPDRMYIMYTSG 1872 ++ + +II+L E + + ++NP +G + +YI+YTSG Sbjct: 2577 TTLPEYQG----RIISLDTDPELMTIER-----------KDNPVSGLSRDNLIYIIYTSG 2621 Query: 1873 STGKPKGVLVTHSNVLNFVTWSIGELQLQPKDALLLVTSISFDISVFEIFAALLSGSRLC 1932 STGKPKG + TH V+N + W QL +D +L T SFD+S +E + L++G+ L Sbjct: 2622 STGKPKGTMNTHQGVVNRLLWMEETYQLTSRDKVLQKTPFSFDVSGWEFWWPLMTGACLV 2681 Query: 1933 IASMEHLKDTECLLAYMEAQHITIWHSVPSLMVQLMTLLRHHPGRYRHSPVLQQLRHLML 1992 +A E KD L+ ++ + ITI H VPS+ L L S LR + Sbjct: 2682 VAQTEGHKDPSYLIKLIKEKQITILHFVPSM---LQIFLEEADEESCSS-----LRKVFC 2733 Query: 1993 GGEAWSTSLAASLRETF---PQAEIRNMYGPTEATIWVSSYKPGPEIDESHPVMLIGRPI 2049 GEA L +L+E F +AE+ N+YGPTEA I V+ ++ ++D + IGRP+ Sbjct: 2734 SGEA----LTVALQEKFLSILKAELHNLYGPTEAAIDVTFWQ--CQVDSKLSSVPIGRPV 2787 Query: 2050 ANNRLIILDQYGNVCPPGVAGEIYIAGNNVTQGYYNDEEKTRMAFIPQSNGQIF-----Y 2104 AN + ILD P GV GE+Y+ G + +GY N E T FI + F Y Sbjct: 2788 ANTQTYILDANLQPVPVGVPGELYLGGVQLARGYLNRPELTAERFIENPFSEDFSSPRLY 2847 Query: 2105 KTGDSGRYLPEGNVEFTGRRDQLVKVRGYRIELGEIEQALKELTSLQQIAVTAVKDGETS 2164 KTGD RYL +GN+E+ GR D VK+RG+RIELGEIE L + + V ++ + Sbjct: 2848 KTGDLVRYLADGNIEYLGRIDNQVKIRGFRIELGEIETLLASHPEVLETVVIPKEETPGN 2907 Query: 2165 KIVCLYTGDQP---VPQNQLKDAVRKRLPEYMIPAQFFHVERFLLTPNGKMDWRSMEKFV 2221 K + Y +P + +++ ++ +LP YMIP+ F +E LTPNGK+D + + + Sbjct: 2908 KRLVAYLVIRPEITIKIEEIRQFLKAKLPNYMIPSAFVTLEALPLTPNGKVDRKILLESQ 2967 Query: 2222 RETPGSIEAAGIRNEVDKKLSEIWKKLLGIPAVGIQENFFDIGGNSLLVVQM 2273 E S E E+++ L +IW+++L + VGI +NFF+IGG+S+L +++ Sbjct: 2968 EEISRSKEYVAPETEIEETLVKIWQEVLLLEKVGIHDNFFEIGGDSILSIKV 3019 Score = 617 bits (1590), Expect = e-174, Method: Compositional matrix adjust. Identities = 386/1184 (32%), Positives = 633/1184 (53%), Gaps = 66/1184 (5%) Query: 1169 TEIEQQIARIWGNLFQMPNIDIQDNFYELGGTSIMGIKIANRINEQYRVTMTIQDVFTHL 1228 T IE+ +A I + + + + +NF+ELGG S++ ++ ++I + + V + ++ +F Sbjct: 4500 TPIEELLAGILSKILGIETVGVHNNFFELGGHSLIATRVVSQIRQVFNVELPLRSLFEKP 4559 Query: 1229 TVASLGKLVEQKLGTKTEAGAVNKQEVEYAKTSMPLSHAQRRIWFLQKMNPDLVAYNLPF 1288 T+A L K +E+ + + E V+ + V + +PLS AQ+R+WFL ++ PD YN+ Sbjct: 4560 TIAELAKEIEKVINSDVEVEFVSIERVSRNR-ELPLSFAQQRLWFLAELEPDSPFYNISG 4618 Query: 1289 IRYFDMAIDLELLQQAASFLAGRHLLMRTKYVLKDGNPVQEVLPAYVPAVQSIDAAG--Q 1346 +++E L+Q+ + + RH +RT + +DG V + P + ++D + Sbjct: 4619 AVKLQGQLNVEALEQSFNEIVRRHENLRTNFQTRDGQAVAVISPERPLNLSTVDISSLNG 4678 Query: 1347 SDPELFVKMNIHQQKMKPFNLEM-PPYRIYLYTISDERACLYINFHHILTDGWSIDIYYR 1405 S E V+ I ++ KPF++ RI L + +E + + HHI++DGWS+ ++ + Sbjct: 4679 STQEEKVRQEITKEAEKPFDISKDLLLRIKLLHLGEEENIVLVTMHHIISDGWSMGVFIK 4738 Query: 1406 ELFSLYQAFLHQQPPRLPEVKEDYFDWILEQKAWEESEAFVEHEQFWLKELAKPLPVLSL 1465 EL +LY F +Q+P L E+ Y D+ Q+ W + E +WLK+L +L L Sbjct: 4739 ELGTLYTNFCNQEPISLQELPIQYVDFAAWQREWLQGEVLENQVSYWLKQLENTPKLLEL 4798 Query: 1466 PSDHKAPAVQTYRGSFHKFTISGELYRKLKAHLETQQITANNFLLSAYFLLLHNLSQEQD 1525 P++ PA+QT+ G+ H F +S EL L + + T LL+ + LL + ++D Sbjct: 4799 PTNKPRPAIQTFNGATHSFELSKELSLALNKLSQQKGSTLFMTLLAGFQTLLWRYTAQED 4858 Query: 1526 IIIGVPASGRNEQKWESVAGIFINTLCIRIHFQGITTFMELQDAVKHKVWSAMDKAQYPF 1585 +++G P + RN + E + G F+NTL +R + +F EL + V+ A PF Sbjct: 4859 VVVGSPIANRNRGEIEGLIGFFVNTLVLRTNLAENPSFSELLEQVREVTLGAYSHQDVPF 4918 Query: 1586 DLLVEKVNPDRDLSRNPIYNVLFQFYDK------------LYLENE-GISPFELSCLAQE 1632 +LLVE++ P+RDLS +P++ V+F + LEN+ + F+LS E Sbjct: 4919 ELLVERLQPERDLSHSPLFQVMFVLQNAPMSALELPGVTLTSLENKHQTAKFDLSLYMTE 4978 Query: 1633 TNQQIEISFEYNSDMYTDSTISRFAGYFLNIIGQVVDKPXXXXXXXXXXXXXXXXXXXSR 1692 T + SFEYN+D++ + TI+R G+ ++ +V P S Sbjct: 4979 TESGLVGSFEYNTDLFEEETITRMVGHLERLLSAIVANPEQRLSDLPLLSEPEQHQLLSE 5038 Query: 1693 FQGEQADLEDGQTIHGRFEAQVQKNPHAIALVYEEQQMTFQEVNGKANQLAWMLTGSGVQ 1752 + + + +H FE QV+K P A+A+ +E+Q++T+ E+N KANQLA L GV+ Sbjct: 5039 WNETKVEY-SSLCVHQLFEVQVEKTPLAVAVEFEDQKLTYHELNRKANQLAHYLRSLGVK 5097 Query: 1753 RNTPVGIFVDRSFSSVIGILAILKAGGAYVPLDPGYPEDRIAYILAHSGAKWLLTENRYL 1812 VGI V+RS VIG+LAILKAGGAY+PLDP YP++RI +IL + LLT+ + Sbjct: 5098 PEVLVGICVERSLEMVIGLLAILKAGGAYLPLDPNYPQERIQFILEETQVPVLLTQASLM 5157 Query: 1813 QSVAAFAHEEGIQIINL---SPVKEQSAVSQMYLADYEDELSRENPRTGGHGPDRMYIMY 1869 ++ E Q++ + SP EQ + + D L+ Y +Y Sbjct: 5158 DTMP----ENTAQLVCIEKNSPDIEQQSQDNLISNLTTDNLA--------------YTIY 5199 Query: 1870 TSGSTGKPKGVLVTHSNVLNFVTWSIGELQLQPKDALLLVTSISFDISVFEIFAALLSGS 1929 TSGSTG+PKGV + HS++ NF+ E L KD LL VT+ SFDI+ E+F L+ G+ Sbjct: 5200 TSGSTGQPKGVQIPHSSLSNFLFSMKEEPGLSSKDTLLAVTTYSFDIAALELFLPLIVGA 5259 Query: 1930 RLCIASMEHLKDTECLLAYMEAQHITIWHSVPSLMVQLMTLLRHHPGRYRHSPVLQQLRH 1989 RL +AS E + D LLA + T+ + P+ L+ + + +QL+ Sbjct: 5260 RLIVASQEIVADGTQLLAKLTDSKTTVMQATPATWKLLIA------AGWEGN---EQLK- 5309 Query: 1990 LMLGGEAWSTSLAASLRETFPQAEIRNMYGPTEATIWVSSYKPGPEIDESHPVMLIGRPI 2049 ++ GGE + LA+ L E + NMYGPTE TIW + EI ++ IG I Sbjct: 5310 VLCGGETLPSQLASELLERC--ESLWNMYGPTETTIWSAV----SEIKTDSQLISIGNGI 5363 Query: 2050 ANNRLIILDQYGNVCPPGVAGEIYIAGNNVTQGYYNDEEKTRMAFI--PQSNGQI-FYKT 2106 AN +L ILDQ + P GV GE+ I G + +GY+ E + FI P S + Y+T Sbjct: 5364 ANTQLYILDQSSQLVPVGVVGELCIGGEGLARGYFQRRELNKEKFIYNPFSEEESRIYRT 5423 Query: 2107 GDSGRYLPEGNVEFTGRRDQLVKVRGYRIELGEIEQALKELTSLQQIAVTAVKDGETSKI 2166 GD RYLP G +E+ GR D VK+RG+RIELGEIE + + T++++ V A +D K Sbjct: 5424 GDLARYLPNGEIEYLGRIDNQVKIRGFRIELGEIETQIAQYTAVKEAVVIAREDIAGDKR 5483 Query: 2167 VCLYTGDQ---PVPQNQLKDAVRKRLPEYMIPAQFFHVERFLLTPNGKMDWRSMEKFVRE 2223 + Y Q V ++L++ + ++LP YMIP+ F +E+ LTPNGK+D +++ + Sbjct: 5484 LVAYIVPQEELAVNPSELREFLGEKLPNYMIPSAFVMLEKLPLTPNGKIDRKALPVPEKT 5543 Query: 2224 TPGSIEAAGIRNEVDKKLSEIWKKLLGIPAVGIQENFFDIGGNSLLVVQMQGMIQQEFFQ 2283 S E +++ L+ IW ++LGI VGI +FF++GG+SL+ ++ I+Q F Sbjct: 5544 PISSNEIVLPSTPIEELLAGIWTEILGIETVGIHNDFFELGGHSLIATRIMSQIRQVFNV 5603 Query: 2284 DIPMMDLFKYTSIEKISDYLQEHT-----VKVSSVETGQKRADM 2322 DIP+ +LF+ +I +++ +++ V+V S+E + ++ Sbjct: 5604 DIPLRNLFEKPTIAELAKEIEKVINSDVGVEVVSIERVSREQEL 5647 Score = 535 bits (1379), Expect = e-150, Method: Compositional matrix adjust. Identities = 350/1056 (33%), Positives = 539/1056 (51%), Gaps = 89/1056 (8%) Query: 1156 IDVRLTGR------ADQSYTEIEQQIARIWGNLFQMPNIDIQDN--FYELGGTSIMGIKI 1207 I+ +LT R QS +E+E + + ++ + + DI N LG SI + Sbjct: 425 IETKLTRRELLELSKQQSQSELEIYLRSLILSILRRTDQDIDLNTPLTNLGLDSIKVFEF 484 Query: 1208 ANRINEQYRVTMTIQDVFTHLTVASLGKLVEQKLGTKTEAGAVNKQEVEYAKTSMP---- 1263 N+I E VT+ I+D F L + SL + +L T EA ++ +P Sbjct: 485 KNKIEEDMGVTIPIEDFFAELNIKSLCNQILAQLDTPVEA----------SRAIIPTHRD 534 Query: 1264 -----LSHAQRRIWFLQKMNPDLVAYNLPFIRYFDMAIDLELLQQAASFLAGRHLLMRTK 1318 LS AQ+RIWFL ++ PD YN+ ++LE+L+Q+ + + RH +RT Sbjct: 535 GNFYQLSFAQKRIWFLAELEPDNPFYNISGTVRIQGHLNLEVLEQSFNEIIRRHETLRTN 594 Query: 1319 YVLKDGNPVQEVLPAYVP---AVQSIDAAGQSDPELFVKMNIHQQKMKPFNLEMPPY-RI 1374 + +DG V V+ + P ++ + + S E VK ++ KPF++ P R+ Sbjct: 595 FQTRDGKAVA-VIASERPIKLSIVDVSSLSGSTQEEKVKQETAEEAEKPFDISNDPLLRV 653 Query: 1375 YLYTISDERACLYINFHHILTDGWSIDIYYRELFSLYQAFLHQQPPRLPEVKEDYFDWIL 1434 L + E + + HHI++DGWSI + +EL +LY F +Q+P L E+ Y D+ Sbjct: 654 KLLRLEQEENLILVTLHHIISDGWSIGVLLQELTTLYTNFYNQEPLALQELPIQYVDFAA 713 Query: 1435 EQKAWEESEAFVEHEQFWLKELAKPLPVLSLPSDHKAPAVQTYRGSFHKFTISGELYRKL 1494 Q+ W + E +WLK+L VL LP+D+ A+Q+YRG + F +S EL L Sbjct: 714 WQRQWLQGEVLENQMSYWLKQLENAPEVLELPADNPRQAIQSYRGKIYSFNLSKELSTSL 773 Query: 1495 KAHLETQQITANNFLLSAYFLLLHNLSQEQDIIIGVPASGRNEQKWESVAGIFINTLCIR 1554 E Q T LL+ + LL + ++DI++G P + RN + E + G F+N+L +R Sbjct: 774 NELSEQQGTTLFMTLLAGFQTLLWRYTAQEDIVVGSPIANRNRAEVEGLIGFFVNSLVLR 833 Query: 1555 IHFQGITTFMELQDAVKHKVWSAMDKAQYPFDLLVEKVNPDRDLSRNPIYNVLFQFYD-- 1612 + G +F EL V+ A PFDLLVE++ P+R LS NP++ V+F + Sbjct: 834 TNLAGNPSFEELLKQVREVALGAYAHQDVPFDLLVERLQPERQLSHNPLFQVVFALLNTP 893 Query: 1613 -----------KLYLENEGISPFELSCLAQETNQQIEISFEYNSDMYTDSTISRFAGYFL 1661 + + GI+ +L ET I FEYN+D++ + TISR AG+ Sbjct: 894 MSDLDLPDATLTVLRNDSGIARCDLILYMTETESGIAGQFEYNTDLFEEKTISRMAGHIQ 953 Query: 1662 NIIGQVVDKPXXXXXXXXXXXXXXXXXXXSRFQGEQADLEDGQTIHGRFEAQVQKNPHAI 1721 ++ +V+ P + + + + IH FE QV+ P+ I Sbjct: 954 TLLSAIVENPQQKVSEIPLLRATERHQLLVEWNETELEYSQNKCIHQLFEEQVKTKPNGI 1013 Query: 1722 ALVYEEQQMTFQEVNGKANQLAWMLTGSGVQRNTPVGIFVDRSFSSVIGILAILKAGGAY 1781 A+V+EEQQ+T++E+N KANQLA L GV+ ++ VGI V+RS +IG+L ILKAGGAY Sbjct: 1014 AVVFEEQQLTYEELNKKANQLAHYLIKLGVKPDSLVGICVERSLEMIIGVLGILKAGGAY 1073 Query: 1782 VPLDPGYPEDRIAYILAHSGAKWLLTENRYLQSVAAFAHEEGIQIINLSPVKEQSAVSQM 1841 +P+DP YP++RI Y+L S LLT+ R ++ + E QII+L + S ++ Sbjct: 1074 LPIDPDYPQERIEYMLTDSEVNILLTQERLVEKLP----ENNSQIISLD--TDWSQIATK 1127 Query: 1842 YLADYEDELSRENPRTGGHGPDRMYIMYTSGSTGKPKGVLVTHSNVLNFVTWSIGELQLQ 1901 + E++ EN Y++YTSGSTGKPKGV++ H V N ++ Sbjct: 1128 SDINLNQEINAEN---------LAYVIYTSGSTGKPKGVMIEHQGVCNLAQVQRERFKVN 1178 Query: 1902 PKDALLLVTSISFDISVFEIFAALLSGSRLCIASMEHL---KDTECLLAYMEAQHITIWH 1958 + S SFD +EI ALLSG+RL I + ++ E L HIT+ Sbjct: 1179 SSSRIFQFASFSFDACAWEIVMALLSGARLVITDKDKKLPGENLEKTLNEYGITHITLPP 1238 Query: 1959 SVPSLMVQLMTLLRHHPGRYRHSPV-LQQLRHLMLGGEAWSTSLAASLRETFPQAEIRNM 2017 S ++M SP L Q++ ++L GEA +LAA +E ++ N Sbjct: 1239 SALTVM----------------SPENLTQVKTIILAGEACPGTLAALWQEG---RDLFNG 1279 Query: 2018 YGPTEATIWVSSYKPGPEIDESHPVMLIGRPIANNRLIILDQYGNVCPPGVAGEIYIAGN 2077 YGPTE T+ + + ++++ + IGRPIAN ++ ILD+ P GV+GE++I G+ Sbjct: 1280 YGPTEDTVCATIGEYQQDLEK----LPIGRPIANQQVYILDKNLEPVPIGVSGELHIGGD 1335 Query: 2078 NVTQGYYNDEEKTRMAFI--PQSNGQIFYKTGDSGRYLPEGNVEFTGRRDQLVKVRGYRI 2135 + +GY N E T FI P ++ + YKTGD RYL +GN+EF GR D VK+RG+RI Sbjct: 1336 GLARGYLNRPELTAEKFISNPWNSAEKLYKTGDLARYLADGNIEFVGRIDDQVKIRGFRI 1395 Query: 2136 ELGEIEQALKELTSLQQIAVTAVKDGETSKIVCLYT 2171 ELGE+E AL +QQ V +DG +K + Y Sbjct: 1396 ELGEVETALDSHPQIQQAVVIPREDGPGNKRLIAYV 1431 Score = 445 bits (1145), Expect = e-123, Method: Compositional matrix adjust. Identities = 334/1076 (31%), Positives = 536/1076 (49%), Gaps = 79/1076 (7%) Query: 1263 PLSHAQRRIWFLQKMNPDLVAYNLPFIRYFDMAIDLELLQQAASFLAGRHLLMRTKYVLK 1322 PLS Q + F P+ Y I+L + A + RH ++RT +V + Sbjct: 3541 PLSPMQEGMLFHTISEPESGVYFQQIALGLTGNIELLAFESAWQKVVDRHSVLRTFFVAE 3600 Query: 1323 D-GNPVQEVLPAYVPAVQSIDAAGQSDPELFVKMN--IHQQKMKPFNLEMPP-YRIYLYT 1378 D P+Q VL +++D G S + +++ + Q+++ F L P + L Sbjct: 3601 DVEKPLQIVLKQVKLPWENMDWRGLSQQKQQEQLDELLSSQRLEGFQLNQAPLMKCILIE 3660 Query: 1379 ISDERACLYINFHHILTDGWSIDIYYRELFSLYQAFLHQQPPRLPEVK--EDYFDWILEQ 1436 +S+ ++ HHIL DGW + I ++E+ S+Y+A + + LP + EDY DW+ Q Sbjct: 3661 LSENNYKFVLSSHHILMDGWCLPIIFKEVLSIYEAEIQGKNFNLPRPRPYEDYIDWLKLQ 3720 Query: 1437 KAWEESEAFVEHEQFW---LKELAKPLPVLSLPSDHKAPAVQTYRGSFHK--FTISGELY 1491 S QFW L+ P P++ S ++ Q + ++ + +S +L Sbjct: 3721 NKETAS-------QFWQETLQGFTAPTPLVVEKSQYQT---QLNKSNYQEIELRLSPQLS 3770 Query: 1492 RKLKAHLETQQITANNFLLSAYFLLLHNLSQEQDIIIGVPASGRNEQ--KWESVAGIFIN 1549 R+L+A + +T + + + LLL S E+DI+ GV SGR + E G+FIN Sbjct: 3771 RELQALSQKYHLTLSTIMQGVWGLLLSGYSGEEDIVFGVTVSGRPPSLPEVEKRVGLFIN 3830 Query: 1550 TLCIRIHFQGITTFMELQDAVKHKVWSAMDKAQYPFDLLVEKVNPDRDLSRNPIYNVLFQ 1609 TL +RI + + ++ + A D A P LV+ P++ + Sbjct: 3831 TLPLRIQIPPQQQLIPWLEEIQQLMSQAQDYAYTP---LVDIKAVSEVPGGMPLFETIMV 3887 Query: 1610 FYD---------KLYLENEGISPFE-----LSCLAQETNQQIEISFEYNSDMYTDSTISR 1655 F + LE I FE L+ +A +Q+ I Y++ + TI R Sbjct: 3888 FENYPIGRSLTKDSALEISKIQSFEQTNYPLTVMAV-PGEQLLIRVSYDTVRFESETIER 3946 Query: 1656 FAGYFLNIIGQVVDKPXXXXXXXXXXXXXXXXXXXSRFQGEQADLEDGQTIHGRFEAQVQ 1715 + + + +V P + + + + FEAQV+ Sbjct: 3947 MSEHLETMFSAIVKNPQQRVREIPLLTETERHQLLWEWNDTKVEY-SLLCVDQLFEAQVE 4005 Query: 1716 KNPHAIALVYEEQQMTFQEVNGKANQLAWMLTGSGVQRNTPVGIFVDRSFSSVIGILAIL 1775 K P A+A+ +E+Q++T+Q++N KANQLA L GV+ VGI V+RS VIG+LAIL Sbjct: 4006 KTPDAVAVEFEDQKLTYQQLNTKANQLAHYLRCLGVKPEVLVGICVERSLEMVIGLLAIL 4065 Query: 1776 KAGGAYVPLDPGYPEDRIAYILAHSGAKWLLTENRYLQSVAAFAHEEGIQIINLSPVKEQ 1835 KAGGAY+PLDP YP++RI +IL + LLT+ L ++ H + I+ K+ Sbjct: 4066 KAGGAYLPLDPNYPQERIQFILEETQVPVLLTQASLLDAMP--KHRAQVLCID----KDS 4119 Query: 1836 SAVSQMYLADYEDELSRENPRTGGHGPDRMYIMYTSGSTGKPKGVLVTHSNVLNFVTWSI 1895 + Q + E++ +N Y +YTSGSTGKPKGV + HS + NF+ Sbjct: 4120 PDIEQQSQENITSEVTTDN---------LAYTIYTSGSTGKPKGVQIPHSALSNFLFSMK 4170 Query: 1896 GELQLQPKDALLLVTSISFDISVFEIFAALLSGSRLCIASMEHLKDTECLLAYMEAQHIT 1955 E L KD LL VT+ SFDI+ E+F L+ G+RL +AS E + D LLA + T Sbjct: 4171 EEPGLSSKDTLLAVTTYSFDIAALELFLPLVVGARLIVASQEIVADGTQLLATLTDSKTT 4230 Query: 1956 IWHSVPSLMVQLMTLLRHHPGRYRHSPVLQQLRHLMLGGEAWSTSLAASLRETFPQAEIR 2015 + + P+ L+ ++ + +QL+ ++ GGEA + LA+ L E + Sbjct: 4231 VMQATPATWKLLIA------ADWQGN---EQLK-VLCGGEALPSQLASELLERC--ESLW 4278 Query: 2016 NMYGPTEATIWVSSYKPGPEIDESHPVMLIGRPIANNRLIILDQYGNVCPPGVAGEIYIA 2075 NMYGPTE TIW + EI ++ IG IAN +L ILDQ + P GV GE+ I Sbjct: 4279 NMYGPTETTIWSAV----SEIKTDSQLISIGNGIANTQLYILDQSSQLVPVGVVGELCIG 4334 Query: 2076 GNNVTQGYYNDEEKTRMAFI--PQSNGQI-FYKTGDSGRYLPEGNVEFTGRRDQLVKVRG 2132 G + +GY+ E + FI P S + Y+TGD RYLP G +E+ GR D VK+RG Sbjct: 4335 GMGLARGYFERPELNKEKFIYNPFSEEESRIYRTGDLARYLPNGEIEYLGRIDNQVKIRG 4394 Query: 2133 YRIELGEIEQALKELTSLQQIAVTAVKDGETSKIVCLYTGDQ---PVPQNQLKDAVRKRL 2189 +RIELGEIE + + T++++ V A +D K + Y Q V ++L++ + ++L Sbjct: 4395 FRIELGEIETQIAQYTAVKEAVVIAREDIAGDKRLVAYIVPQEELAVNPSELREFLGEKL 4454 Query: 2190 PEYMIPAQFFHVERFLLTPNGKMDWRSMEKFVRETPGSIEAAGIRNEVDKKLSEIWKKLL 2249 P YMIP+ F +E+ LTPNGK+D +++ + S E +++ L+ I K+L Sbjct: 4455 PNYMIPSAFVMLEKLPLTPNGKIDRKALPEPQETEILSEEIVLPSTPIEELLAGILSKIL 4514 Query: 2250 GIPAVGIQENFFDIGGNSLLVVQMQGMIQQEFFQDIPMMDLFKYTSIEKISDYLQE 2305 GI VG+ NFF++GG+SL+ ++ I+Q F ++P+ LF+ +I +++ +++ Sbjct: 4515 GIETVGVHNNFFELGGHSLIATRVVSQIRQVFNVELPLRSLFEKPTIAELAKEIEK 4570 Score = 254 bits (650), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 151/522 (28%), Positives = 286/522 (54%), Gaps = 23/522 (4%) Query: 1169 TEIEQQIARIWGNLFQMPNIDIQDNFYELGGTSIMGIKIANRINEQYRVTMTIQDVFTHL 1228 T IE+ +A IW + + + I ++F+ELGG S++ +I ++I + + V + ++++F Sbjct: 5555 TPIEELLAGIWTEILGIETVGIHNDFFELGGHSLIATRIMSQIRQVFNVDIPLRNLFEKP 5614 Query: 1229 TVASLGKLVEQKLGTKTEAGAVNKQEVEYAKTSMPLSHAQRRIWFLQKMNPDLVAYNLPF 1288 T+A L K +E+ + + V+ + V + +PLS AQ+R+WFL ++ PD YN+ Sbjct: 5615 TIAELAKEIEKVINSDVGVEVVSIERVSREQ-ELPLSFAQQRLWFLAQIEPDSPFYNMSS 5673 Query: 1289 IRYFDMAIDLELLQQAASFLAGRHLLMRTKYVLKDGNPVQEVLPAYVPAVQSIDAAG--- 1345 + +I++ +L+Q+ + + RH +RT + + + P+Q + P + +ID Sbjct: 5674 TIEVEGSINVAVLEQSFNEIIRRHESLRTTFAMGENGPIQIIAPEQSIKITTIDLHNLDV 5733 Query: 1346 QSDPELFVKMNIHQQKMKPFNL-EMPPYRIYLYTISDERACLYINFHHILTDGWSIDIYY 1404 E K+ + + + PFNL + RI L + + + L +N HHI++D WS+ + Sbjct: 5734 NEQTEQVQKLALEEAQT-PFNLADGLLIRISLLQLGERKNVLLLNIHHIISDAWSMGVLV 5792 Query: 1405 RELFSLYQAFLHQQPPRLPEVKEDYFDWILEQKAWEESEAFVEHEQFWLKELAKPLPVLS 1464 +EL + Y+ ++ +P +LPE+ Y D+ + Q+ ++E + +W ++L+ + Sbjct: 5793 KELATFYENLVNDKPVQLPELPIQYADFAVWQRQPLQAEKLDKQLAYWRQQLSGVPDSFN 5852 Query: 1465 LPSDHKAPAVQTYRGSFHKFTISGELYRKLKAHLETQQ-ITANNFLLSAYFLLLHNLSQE 1523 +P+D P +QT+RG+ +F++S EL K+ HL Q+ +T LL+ LLL+ ++ Sbjct: 5853 IPTDKPRPELQTFRGAVSEFSLSTELSEKV-THLSRQEGVTLFMTLLATLQLLLYKYKKQ 5911 Query: 1524 QDIIIGVPASGRNEQKWESVAGIFINTLCIRIHFQGITTFMELQDAVKHKVWSAMDKAQY 1583 +D+++G + RN ++ ES+ G FIN L +R +F G TF EL + V+ A + Sbjct: 5912 KDVLVGTDVANRNYKEVESLIGFFINILVLRANFSGNPTFRELLEQVREVTLGAYANQDF 5971 Query: 1584 PFDLLVEKVNPDRDLSRNPIYNVLFQF--------------YDKLYLENEGISPFELSCL 1629 PF LVE V P+R+LSR P++ VLF + L ++ E S F+++ Sbjct: 5972 PFTKLVETVRPERNLSRTPLFQVLFVLNNTPIPQLEVSGLKFTPLMVDTE-TSKFDMALF 6030 Query: 1630 AQETNQQIEISFEYNSDMYTDSTISRFAGYFLNIIGQVVDKP 1671 ET ++ ++YNSD++ ST++R + F ++ +V++P Sbjct: 6031 VSETETGLKGMWQYNSDLFDLSTMTRLSAQFETLLNNIVNQP 6072 Score = 90.9 bits (224), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 93/386 (24%), Positives = 162/386 (41%), Gaps = 40/386 (10%) Query: 1169 TEIEQQIARIWGNLFQMPNIDIQDNFYELGGTSIMGIKIANRINEQYRVTMTIQDVFTHL 1228 TEIE+ + +IW + + + I DNF+E+GG SI+ IK+ +R + + + + +F + Sbjct: 2981 TEIEETLVKIWQEVLLLEKVGIHDNFFEIGGDSILSIKVVSRA-KNAGLQIRSKQIFENQ 3039 Query: 1229 TVASLGKLVEQKLGTKTEAGAVNKQEVEYAKTSMPLSHAQRRIWFLQKMNPDLVAYNLPF 1288 T+A L + + K T E G V PL+ Q+ WFL K + +N Sbjct: 3040 TIAELALVAKIKTETIAEQGIVTG--------IAPLTPIQK--WFLDKNPKEAHHFNQSV 3089 Query: 1289 IRYFDMAIDLELLQQAASFLAGRHLLMRTKY--------VLKDGNPVQEVLPAYVPAVQS 1340 I I+ E+++++ L H +R ++ + +G V +L + Sbjct: 3090 ILEIPGEIEAEIVEKSVQKLLEHHDALRLRFNRETLEDKQINEGLGVTNLLTIVDLSSTP 3149 Query: 1341 IDAAGQSDPELFVKMNIHQQKMKPFNLEMPP-YRIYLYTISD-ERACLYINFHHILTDGW 1398 + G+ E+ + NL P ++ L+ + + + L I HH++ DG Sbjct: 3150 KEYQGERIAEIATEFQ------GSLNLRNGPLMQVVLFNLGEADNNRLLIIIHHLVVDGV 3203 Query: 1399 SIDIYYRELFSLYQAFLHQQPPRLPEVKEDYFDWILEQKAWEESEAFVEHEQFWLKELAK 1458 S I +L + Q Q+P +L E + W E + ++E +WL + Sbjct: 3204 SWRILLSDLEEISQKLTAQEPAKLREKTIAFIKWAEELNKYAQTEEVEAELDYWLYKNWT 3263 Query: 1459 PLPVLSLPSDHKAP------AVQTYRGSFHKFTISGELYRKLKAHL-ETQQITANNFLLS 1511 V+ L + K P VQ R +S E RKL + E N+ LLS Sbjct: 3264 KTGVIPLDCEEKEPENLVGDVVQVSR------KLSVEATRKLLGEVNEAYNTQINDILLS 3317 Query: 1512 AYFLLLHNLSQEQDIIIGVPASGRNE 1537 A ++L + +II + GR E Sbjct: 3318 ALKIVLGEWTNSSSVIINLEGHGREE 3343 Score = 82.4 bits (202), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 39/127 (30%), Positives = 78/127 (61%) Query: 2179 NQLKDAVRKRLPEYMIPAQFFHVERFLLTPNGKMDWRSMEKFVRETPGSIEAAGIRNEVD 2238 +QL + + +LP YM+P+ F +E LTPNGK++ +++ + S E ++ Sbjct: 1862 SQLPEFLLSKLPNYMVPSAFVTLEALPLTPNGKINRKALPDPLETQILSEEIVLPSTPIE 1921 Query: 2239 KKLSEIWKKLLGIPAVGIQENFFDIGGNSLLVVQMQGMIQQEFFQDIPMMDLFKYTSIEK 2298 + L++IW ++LGI VG+ NFF++GG+SL+ ++ I+Q F ++P+ LF+ +I + Sbjct: 1922 ELLADIWTEILGIETVGVNNNFFELGGHSLIATRVVSQIRQVFNVELPLRSLFEKPTIAE 1981 Query: 2299 ISDYLQE 2305 ++ +++ Sbjct: 1982 LAKEIEK 1988 >ref|ZP_00111185.1| COG3319: Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Nostoc punctiforme] Length = 4617 Score = 618 bits (1594), Expect = e-175, Method: Compositional matrix adjust. Identities = 385/1196 (32%), Positives = 624/1196 (52%), Gaps = 61/1196 (5%) Query: 1146 REQIKHPEAEIDVRLTGRADQSYTEIEQQIARIWGNLFQMPNIDIQDNFYELGGTSIMGI 1205 R+ + PE D +L A + T IE+ + IW N+ ++ I I DNF+ELGG S++ Sbjct: 1046 RKALPAPEMRSDQKLEFEAGR--TPIEEMLTFIWANILKVEQIGIHDNFFELGGNSLLAT 1103 Query: 1206 KIANRINEQYRVTMTIQDVFTHLTVASLGKLVEQKLGTKTEAGAVNKQEVEYAKTSMPLS 1265 ++ ++ + + ++ +F H TVA L ++++ + + A + + +PLS Sbjct: 1104 QVIAQVRSTISLEIPLRSLFQHPTVAKLAQIIQLAIQPDEQLTAPPLRPIA-RDGELPLS 1162 Query: 1266 HAQRRIWFLQKMNPDLVAYNLPFIRYFDMAIDLELLQQAASFLAGRHLLMRTKYVLKDGN 1325 AQ R+WFL ++ P YN+P +D+ LQ++ + + RH +RT + DG Sbjct: 1163 FAQARLWFLNQLQPHSAFYNIPVFLRMAGQLDVVALQESINEIIRRHEALRTNFTATDGI 1222 Query: 1326 PVQEVLPAYVPAVQSIDAAGQSDPELFVKMNIHQ----QKMKPFNLEMPPY-RIYLYTIS 1380 PVQ + + ++ ID QS PE ++ + +PF+L P R L + Sbjct: 1223 PVQVIAATHNLTLEVIDL--QSLPEAARELETTRLGTDSAQQPFDLAQEPLVRTKLVQVH 1280 Query: 1381 DERACLYINFHHILTDGWSIDIYYRELFSLYQAFLHQQPPRLPEVKEDYFDWILEQKAWE 1440 L + HHI++DGWS+ ++ REL +LY A+ QP LP++ Y D+ Q+ W Sbjct: 1281 QTEHVLLLTMHHIISDGWSMGVFVRELAALYNAYSQGQPSPLPKLSVQYVDFAAWQRKWL 1340 Query: 1441 ESEAFVEHEQFWLKELAKPLPVLSLPSDHKAPAVQTYRGSFHKFTISGELYRKLKAHLET 1500 + E +W K+LA +L+LP+D PA Q++RGS + TI EL + L+ Sbjct: 1341 QGEVLESQLNYWQKKLAGVSTLLALPTDRPRPAFQSFRGSHQQITIPVELSQALRLLSRQ 1400 Query: 1501 QQITANNFLLSAYFLLLHNLSQEQDIIIGVPASGRNEQKWESVAGIFINTLCIRIHFQGI 1560 Q +T LL+A+ LL+ + DI +G P + R Q+ E + G F+NTL +R G Sbjct: 1401 QGVTLFMTLLAAFDTLLYRYTSSDDICVGTPIANRQHQEIEGLIGFFVNTLVMRTDLSGN 1460 Query: 1561 TTFMELQDAVKHKVWSAMDKAQYPFDLLVEKVNPDRDLSRNPIYNVLFQFYD--KLYLEN 1618 +F EL V+ A PF+ LVE + P+R LS P++ V+F + L+ Sbjct: 1461 PSFAELLSRVRSVALEAYTHQDIPFEQLVEALQPERSLSHTPLFQVMFDLQNVPMSALDM 1520 Query: 1619 EGIS-----------PFELSCLAQETNQQIEISFEYNSDMYTDSTISRFAGYFLNIIGQV 1667 G+S F+L+ ET+ ++ +EY++D++ +TI+R AG+F ++ + Sbjct: 1521 TGLSMSSLTVETDTTKFDLTLSILETDLELVGVWEYDTDLFDAATITRMAGHFQLLLEGI 1580 Query: 1668 VDKPXXXXXXXXXXXXXXXXXXXSRFQGEQADLEDGQTIHGRFEAQVQKNPHAIALVYEE 1727 V P + QAD + IH FE QV + P A+A+V+E Sbjct: 1581 VANPQQQLSELPLLSKPERNQLLVEWNDTQADYPYDKCIHQLFEEQVARTPDAVAVVFEN 1640 Query: 1728 QQMTFQEVNGKANQLAWMLTGSGVQRNTPVGIFVDRSFSSVIGILAILKAGGAYVPLDPG 1787 QQ+T+Q++N +ANQLA L GV+ +T VGI ++RS V+G+L ILKAGGAYVPLDPG Sbjct: 1641 QQLTYQQLNNRANQLAHYLQSLGVKPDTLVGICIERSLEMVVGLLGILKAGGAYVPLDPG 1700 Query: 1788 YPEDRIAYILAHSGAKWLLTENRYLQSVAAFAHEEGIQIINLSPVKEQSAVSQMYLADYE 1847 YP +R+ Y L+ + LLT+ ++ + E Q++ L + ADY Sbjct: 1701 YPSERLGYALSDAQISVLLTQQHLVEKLP----EHQAQVVYLD-----QNWDAILTADYA 1751 Query: 1848 -DELSRENPRTGGHGPDRMYIMYTSGSTGKPKGVLVTHSNVLNFVTWSIGELQLQPKDAL 1906 + ++N + + Y++YTSGSTGKPKGV + H + + V W+ + + Sbjct: 1752 YAQFPKDNVHSQVQPTNLAYVLYTSGSTGKPKGVAIEHHSPVALVAWAKEVFTPEQLAGV 1811 Query: 1907 LLVTSISFDISVFEIFAALLSGSRLCIASMEHLKDTECLLAYMEAQHITIWHSVPSLMVQ 1966 L TSI FD+SVFE+F L G ++ +A ++ L A+ +T+ ++VPS++ + Sbjct: 1812 LACTSICFDLSVFELFVPLSWGRKVILA-----ENALHLPTLPAAEQVTLINTVPSVITE 1866 Query: 1967 LMTLLRHHPGRYRHSPVLQQLRHLMLGGEAWSTSLAASLRETFPQAEIRNMYGPTEATIW 2026 L+ + PG + + L GE L + + I N+YGP+E T + Sbjct: 1867 LIR-INGLPGG---------VSTVNLAGEPLQNQLVQQIYQQQIVKYIFNLYGPSEDTTY 1916 Query: 2027 VSSYKPGPEIDESHPVMLIGRPIANNRLIILDQYGNVCPPGVAGEIYIAGNNVTQGYYND 2086 + + P IGRPIAN ++ ILD+Y P GVAGE++IAG + +GY N Sbjct: 1917 STFALIEKGTTFAPP---IGRPIANTQIYILDEYLQPVPVGVAGELHIAGAGLARGYLNR 1973 Query: 2087 EEKTRMAFIPQSNG----QIFYKTGDSGRYLPEGNVEFTGRRDQLVKVRGYRIELGEIEQ 2142 + T FIP YKTGD RYLP+GN+E+ GR D VK+RG+RIELGEIE Sbjct: 1974 PQLTIEKFIPNPFSTDPHSRLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEA 2033 Query: 2143 ALKELTSLQQIAVTAVKDGETSK-IVCLYTGDQPVPQ--NQLKDAVRKRLPEYMIPAQFF 2199 L +L +Q V A +D K +V DQ ++L+ +++ +LPEYM+P F Sbjct: 2034 VLSQLGDVQASCVIAREDTPGDKRLVAYVVADQHCTTTISELRHSLKAKLPEYMVPNAFV 2093 Query: 2200 HVERFLLTPNGKMDWRSMEKFVRETPGSIEAAGIRNEVDKKLSEIWKKLLGIPAVGIQEN 2259 +E LTPNGK+D ++ + + R +++ L++IW ++L + VGI +N Sbjct: 2094 VLESLPLTPNGKVDRHALPTPDLHSERIEKYVSPRTPIEEMLAQIWAQVLKVEQVGIYDN 2153 Query: 2260 FFDIGGNSLLVVQMQGMIQQEFFQDIPMMDLFKYTSIEKIS---DYLQEHTVKVSS 2312 FF++GG+SLL Q+ I+ F ++P+ LF ++ +++ + LQ+ ++++S Sbjct: 2154 FFELGGHSLLATQLLSRIRNTFKVELPLRSLFAAATVAELAQEIEQLQQQGLELTS 2209 Score = 611 bits (1576), Expect = e-173, Method: Compositional matrix adjust. Identities = 381/1177 (32%), Positives = 619/1177 (52%), Gaps = 63/1177 (5%) Query: 1169 TEIEQQIARIWGNLFQMPNIDIQDNFYELGGTSIMGIKIANRINEQYRVTMTIQDVFTHL 1228 T IE+ +A+IW + ++ + I DNF+ELGG S++ ++ +RI ++V + ++ +F Sbjct: 2129 TPIEEMLAQIWAQVLKVEQVGIYDNFFELGGHSLLATQLLSRIRNTFKVELPLRSLFAAA 2188 Query: 1229 TVASLGKLVEQ--KLGTKTEAGAVNKQEVEYAKTSMPLSHAQRRIWFLQKMNPDLVAYNL 1286 TVA L + +EQ + G + + + + V+ A+ + LS AQ+R+WFL ++ P+ YN+ Sbjct: 2189 TVAELAQEIEQLQQQGLELTSSPILPR-VDNAE--LLLSFAQQRLWFLDQLEPNSALYNI 2245 Query: 1287 PFIRYFDMAIDLELLQQAASFLAGRHLLMRTKYVLKDGNPVQ--EVLPAYVPAVQSIDAA 1344 P + ++ L+Q+ + RH +RT ++ +G P Q + ++ +V Sbjct: 2246 PLTLRIVGTLSVKALEQSLEEIIHRHEALRTNFITIEGKPSQIIQTQTNWIVSVVDYQHL 2305 Query: 1345 GQSDPELFVKMNIHQQKMKPFNLEMPPY-RIYLYTISDERACLYINFHHILTDGWSIDIY 1403 S+ E+ + +Q ++PF+L + L ++ L + HHI++DGWS+ ++ Sbjct: 2306 STSEQEIATQQLAQKQLIQPFDLATEALIKATLVVLNKTEHVLLVCMHHIVSDGWSMGVF 2365 Query: 1404 YRELFSLYQAFLHQQPPRLPEVKEDYFDWILEQKAWEESEAFVEHEQFWLKELAKPLPVL 1463 +EL LY A+ QP L + Y D+ + Q+ W + + +W ++LA +L Sbjct: 2366 VQELAVLYNAYSIGQPSSLAPLPIQYADFAIWQRQWLQGDILQSQLSYWQQQLADAPGLL 2425 Query: 1464 SLPSDHKAPAVQTYRGSFHKFTISGELYRKLKAHLETQQITANNFLLSAYFLLLHNLSQE 1523 SLP+D PAVQ++ G++ +F +S +L L + Q +T LL+AY LL+ + Sbjct: 2426 SLPTDRPRPAVQSFAGAYQQFALSKQLTSGLIQLSQEQGVTLFMTLLAAYDTLLYRYTGV 2485 Query: 1524 QDIIIGVPASGRNEQKWESVAGIFINTLCIRIHFQGITTFMELQDAVKHKVWSAMDKAQY 1583 DI++G P + R+ + E + G F+NTL +R G +F EL D V+ A Sbjct: 2486 ADILLGSPIANRDRSEIEGLIGFFVNTLVMRTDLSGNPSFCELLDRVREMAMDAYSHQDL 2545 Query: 1584 PFDLLVEKVNPDRDLSRNPIYNVLFQFYD----KLYLENEGISP---------FELSCLA 1630 PF++LVE + P+RDLS P++ V F + +L L +SP F+L+ L Sbjct: 2546 PFEMLVEALQPERDLSHTPLFQVAFVLQNAPMSQLELTGLTVSPLVVEGTTSRFDLTLLM 2605 Query: 1631 QETNQQIEISFEYNSDMYTDSTISRFAGYFLNIIGQVVDKPXXXXXXXXXXXXXXXXXXX 1690 + T + +EYN+D++ STI R G+F+ ++ ++ P Sbjct: 2606 ENTGTGLVGLWEYNTDLFDSSTIERMTGHFMTLLEGIIANPEERISQLPLLTQVEQHQLL 2665 Query: 1691 SRFQGEQADLEDGQTIHGRFEAQVQKNPHAIALVYEEQQMTFQEVNGKANQLAWMLTGSG 1750 + Q D Q IH FE QV++ P A+A+VYE QQ T++E+N KANQLA L G Sbjct: 2666 VEWNDTQVDYPQDQCIHQLFEEQVERTPDAVAVVYENQQFTYRELNAKANQLAHYLQTLG 2725 Query: 1751 VQRNTPVGIFVDRSFSSVIGILAILKAGGAYVPLDPGYPEDRIAYILAHSGAKWLLTENR 1810 V + VG+ V+RS +++GIL ILKAGGAYVPLDP YP +R+ +IL + LLT+ Sbjct: 2726 VGPDVVVGLCVERSLETIVGILGILKAGGAYVPLDPEYPTERLQFILEDAQVSVLLTQQ- 2784 Query: 1811 YLQSVAAFAHEEGIQIINLSPVKEQSAVSQMYLADYED--ELSRENPRTGGHGPDRMYIM 1868 Q++N P K Q+ V + +D+E + S N + Y++ Sbjct: 2785 --------------QLVNSLP-KHQARVICLD-SDWEKIAQKSESNSLNTTTSDNLAYVI 2828 Query: 1869 YTSGSTGKPKGVLVTHSNVLNFVTWSIGELQLQPKDALLLVTSISFDISVFEIFAALLSG 1928 YTSGSTGKPKGVLV HSNV+ + +D L S +FD SV+EI+ ALL G Sbjct: 2829 YTSGSTGKPKGVLVNHSNVVRLFEATNSWYSFNAQDVWTLFHSYAFDFSVWEIWGALLYG 2888 Query: 1929 SRLCIASMEHLKDTECLLAYMEAQHITIWHSVPSLMVQLMTLLRHHPGRYRHSPVLQQLR 1988 RL + + E + + +TI + PS QL+ + + LR Sbjct: 2889 GRLVVVPYLVTRSPESFFELLTQEKVTILNQTPSAFRQLIQAEQSTATTGNLN-----LR 2943 Query: 1989 HLMLGGEAWSTSLAASLRETFPQ-----AEIRNMYGPTEATIWVSSYKPGPEIDESHPVM 2043 ++ GGEA SL+ F + ++ NMYG TE T+ V +Y+P + D + Sbjct: 2944 LVIFGGEALELK---SLQPWFERHGDQLPQLVNMYGITETTVHV-TYRPLSKADLNSTAS 2999 Query: 2044 LIGRPIANNRLIILDQYGNVCPPGVAGEIYIAGNNVTQGYYNDEEKTRMAFI--PQSNGQ 2101 +IGRPI + ++ +LD+Y P GV GE+Y+ G V +GY N E T FI P N + Sbjct: 3000 VIGRPIRDLQVYVLDEYKQPVPIGVPGEMYVGGAGVARGYLNRPELTAQRFISSPFDNSK 3059 Query: 2102 IFYKTGDSGRYLPEGNVEFTGRRDQLVKVRGYRIELGEIEQALKELTSLQQIAVTAVKDG 2161 + YKTGD RYLP G +E+ GR DQ VK+RG+RIELGEIE L + ++ + V +D Sbjct: 3060 L-YKTGDLARYLPNGELEYLGRIDQQVKIRGFRIELGEIEALLAQHPAVWESVVVIREDE 3118 Query: 2162 ETSKIVCLYT---GDQPVPQNQLKDAVRKRLPEYMIPAQFFHVERFLLTPNGKMDWRSME 2218 K + Y Q +L+ + +LP YM+P F +E LT NGK+D R++ Sbjct: 3119 LDDKRLVAYVVPKVKQSSTAAELRQFLANQLPSYMVPNTFMMLESLPLTSNGKIDRRALP 3178 Query: 2219 KFVRETPGSIEAAGIRNEVDKKLSEIWKKLLGIPAVGIQENFFDIGGNSLLVVQMQGMIQ 2278 K ++ + R ++ L++IW ++L + VGI +NFF++GG+SLL Q+ I+ Sbjct: 3179 KPELDSTLLEKFVAPRTPIEDMLAQIWAQVLKVEQVGIYDNFFELGGHSLLATQLLSRIR 3238 Query: 2279 QEFFQDIPMMDLFKYTSIEKIS---DYLQEHTVKVSS 2312 F ++P+ LF ++ +++ + LQ+ ++++S Sbjct: 3239 NTFKVELPLRSLFAAATVAELAQEIEQLQQQGLELTS 3275 Score = 606 bits (1563), Expect = e-171, Method: Compositional matrix adjust. Identities = 377/1190 (31%), Positives = 626/1190 (52%), Gaps = 59/1190 (4%) Query: 1152 PEAEIDVRLTGRADQSYTEIEQQIARIWGNLFQMPNIDIQDNFYELGGTSIMGIKIANRI 1211 P+ E+D L + T IE +A+IW + ++ + I DNF+ELGG S++ ++ +RI Sbjct: 3178 PKPELDSTLLEKFVAPRTPIEDMLAQIWAQVLKVEQVGIYDNFFELGGHSLLATQLLSRI 3237 Query: 1212 NEQYRVTMTIQDVFTHLTVASLGKLVEQ--KLGTKTEAGAVNKQEVEYAKTSMPLSHAQR 1269 ++V + ++ +F TVA L + +EQ + G + + + + V+ A+ + LS AQ+ Sbjct: 3238 RNTFKVELPLRSLFAAATVAELAQEIEQLQQQGLELTSSPILPR-VDNAE--LLLSFAQQ 3294 Query: 1270 RIWFLQKMNPDLVAYNLPFIRYFDMAIDLELLQQAASFLAGRHLLMRTKYVLKDGNPVQ- 1328 R+WFL ++ P+ YN+P + ++ L+Q+ + RH +RT ++ +G P Q Sbjct: 3295 RLWFLDQLEPNSALYNIPLTLRIVGTLSVKALEQSLEEIIHRHEALRTNFITIEGKPSQI 3354 Query: 1329 -EVLPAYVPAVQSIDAAGQSDPELFVKMNIHQQKMKPFNLEMPPY-RIYLYTISDERACL 1386 + ++ +V S+ E+ + +Q ++PF+L R L +S+ + L Sbjct: 3355 IQTQTNWIVSVVDYQHLSTSEQEIATQQLAQKQLIQPFDLTSEALVRATLIILSETKHIL 3414 Query: 1387 YINFHHILTDGWSIDIYYRELFSLYQAFLHQQPPRLPEVKEDYFDWILEQKAWEESEAFV 1446 + HHI++DGWS ++ +EL LY A+ QP L + Y D+ + Q+ W + + Sbjct: 3415 LVCMHHIVSDGWSTGVFLQELAVLYNAYSQGQPSPLASLPIQYADFAIWQRNWLQGDVLQ 3474 Query: 1447 EHEQFWLKELAKPLPVLSLPSDHKAPAVQTYRGSFHKFTISGELYRKLKAHLETQQITAN 1506 +W ++L +L LP+D PAVQT+ G+ KF +S +L + L + Q +T Sbjct: 3475 TQLNYWQQQLKDAPALLVLPTDRPRPAVQTFAGTHQKFALSEKLTQGLIQLSKEQGVTLF 3534 Query: 1507 NFLLSAYFLLLHNLSQEQDIIIGVPASGRNEQKWESVAGIFINTLCIRIHFQGITTFMEL 1566 LL+ Y LL+ + + DI++G P + R+ + E + G F+NTL +R + G +F EL Sbjct: 3535 MTLLATYDTLLYRYTGQADILVGSPIANRDRNEIEGLIGFFVNTLVMRTNLAGNPSFSEL 3594 Query: 1567 QDAVKHKVWSAMDKAQYPFDLLVEKVNPDRDLSRNPIYNVLFQFYDKLYLENE----GIS 1622 V+ A PF++LVE + P RDLS P++ V+F + E E +S Sbjct: 3595 LTRVRFMAMEAYTHQNLPFEMLVETLQPQRDLSYTPLFQVMFALQNAPMSEVELTGLSVS 3654 Query: 1623 P---------FELSCLAQETNQQIEISFEYNSDMYTDSTISRFAGYFLNIIGQVVDKPXX 1673 P F+L+ Q T + +EY++D++ +TI R G+F+ ++ +V P Sbjct: 3655 PLVVESTTAKFDLTLSMQNTADGLVGVWEYSTDLFDANTIERMTGHFVTLLEGIVANPEE 3714 Query: 1674 XXXXXXXXXXXXXXXXXSRFQGEQADLEDGQTIHGRFEAQVQKNPHAIALVYEEQQMTFQ 1733 + QAD + IH FE QV + P A+A+V+E QQ+T+Q Sbjct: 3715 RISQLPMLTKIERQQLLVEWNDTQADYPYDKCIHQLFEEQVARTPDAVAVVFENQQLTYQ 3774 Query: 1734 EVNGKANQLAWMLTGSGVQRNTPVGIFVDRSFSSVIGILAILKAGGAYVPLDPGYPEDRI 1793 ++N +ANQLA L GV+ +T VGI ++RS V+G+L ILKAGGAYVPLDPGYP +R+ Sbjct: 3775 QLNNRANQLAHYLQSLGVKPDTLVGICIERSLEMVVGLLGILKAGGAYVPLDPGYPSERL 3834 Query: 1794 AYILAHSGAKWLLTENRYLQSVAAFAHEEGIQIINLSPVKEQSAVSQMYLADYE-DELSR 1852 Y L+ + LLT+ ++ + E Q++ L + ADY + + Sbjct: 3835 GYALSDAQISVLLTQQHLVEKLP----EHQAQVVYLD-----QNWDAILTADYAYAQFPK 3885 Query: 1853 ENPRTGGHGPDRMYIMYTSGSTGKPKGVLVTHSNVLNFVTWSIGELQLQPKDALLLVTSI 1912 +N + + Y++YTSGSTGKPKGV + H + + V W+ + +L TSI Sbjct: 3886 DNVHSQVQPTNLAYVLYTSGSTGKPKGVAIEHHSPVALVAWAKEVFTPEQLAGVLACTSI 3945 Query: 1913 SFDISVFEIFAALLSGSRLCIASMEHLKDTECLLAYMEAQHITIWHSVPSLMVQLMTLLR 1972 FD+SVFE+F L G ++ +A ++ L A+ +T+ ++VPS++ +L+ + Sbjct: 3946 CFDLSVFELFVPLSWGRKVILA-----ENALHLPTLPAAEQVTLINTVPSVITELIR-IN 3999 Query: 1973 HHPGRYRHSPVLQQLRHLMLGGEAWSTSLAASLRETFPQAEIRNMYGPTEATIWVSSYKP 2032 PG + + L GE L + + I N+YGP+E T + + Sbjct: 4000 GLPGG---------VSTVNLAGEPLQNQLVQQIYQQQIVKYIFNLYGPSEDTTYSTFALI 4050 Query: 2033 GPEIDESHPVMLIGRPIANNRLIILDQYGNVCPPGVAGEIYIAGNNVTQGYYNDEEKTRM 2092 + P IGRPIAN ++ ILD+Y P GVAGE++IAG + +GY N + T Sbjct: 4051 EKGTTFAPP---IGRPIANTQIYILDEYLQPVPVGVAGELHIAGAGLARGYLNRPQLTIE 4107 Query: 2093 AFIPQSNG----QIFYKTGDSGRYLPEGNVEFTGRRDQLVKVRGYRIELGEIEQALKELT 2148 FIP YKTGD RYLP+GN+E+ GR D VK+RG+RIELGEIE L +L Sbjct: 4108 KFIPNPFSTDPHSRLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAVLSQLG 4167 Query: 2149 SLQQIAVTAVKDGETSK-IVCLYTGDQPVPQ--NQLKDAVRKRLPEYMIPAQFFHVERFL 2205 +Q V A +D K +V DQ ++L+ +++ +LPEYM+P F +E Sbjct: 4168 DVQASCVIAREDTPGDKRLVAYVVADQHCTTTISELRHSLKAKLPEYMVPNAFVVLESLP 4227 Query: 2206 LTPNGKMDWRSMEKFVRETPGSIEAAGIRNEVDKKLSEIWKKLLGIPAVGIQENFFDIGG 2265 LTPNGK+D ++ + + R +++ L++IW ++L + VGI +NFF++GG Sbjct: 4228 LTPNGKVDRHALPTPDLHSERIEKYVSPRTPIEEMLAQIWAQVLKVEQVGIYDNFFELGG 4287 Query: 2266 NSLLVVQMQGMIQQEFFQDIPMMDLFKYTSIEKIS---DYLQEHTVKVSS 2312 +SLL Q+ I+ F ++P+ LF ++ +++ + LQ+ ++++S Sbjct: 4288 HSLLATQLLSRIRNTFKVELPLRSLFAAATVAELAQEIEQLQQQGLELTS 4337 Score = 362 bits (929), Expect = 6e-98, Method: Compositional matrix adjust. Identities = 289/1100 (26%), Positives = 517/1100 (47%), Gaps = 98/1100 (8%) Query: 1262 MPLSHAQRRIWFLQKMNPDL--VAYNLPFIRYFDMAIDLELLQQAASFLAGRHLLMRTKY 1319 PL+ Q+ W + +L VA + +I +D++L ++A L RH ++R Sbjct: 78 FPLTDIQQAYWLGRSSTFELGNVATH-AYIEIDSNNLDIKLFKEAWQKLILRHDMLRA-V 135 Query: 1320 VLKDGNPVQEVLPAYVPAVQSIDAAGQSDPEL-FVKMNIHQQKMKPFNLEMPPYRIYLYT 1378 VL G Q++L A P I + +PE+ VK +++M + +PP + L+ Sbjct: 136 VLPSGE--QQILKAVPPYEIEILNLQEFEPEVAVVKCEEIREQMS--HQVLPPDKWPLFE 191 Query: 1379 I-----SDERACLYINFHHILTDGWSIDIYYRELFSLYQAFLHQQPPRLPEVKEDYFDWI 1433 I +R L+++F ++ D S+ +EL LYQ Q PP ++ + D++ Sbjct: 192 IRATRFDQKRYRLHVSFDLLMADLGSLQQLLKELNQLYQNPETQLPP----LELSFRDYV 247 Query: 1434 LEQKAWEESEAFVEHEQFWLKELAKPLPVLSLPSDHKAPAVQTYRGSFHKFTISGELYRK 1493 L ++ +E++ + + +W L P LP T+ H + + +++ Sbjct: 248 LAERQVKETQLYQRAQSYWWNRLDTLPPAPELPLAKSVLKQPTFVR--HSAQLDQQKWQQ 305 Query: 1494 LKAHLETQQITANNFLLSAYFLLLHNLSQEQDIIIGVPASGRN--EQKWESVAGIFINTL 1551 LK + +T + LL+A+ +L S+ I + R + + G F + Sbjct: 306 LKQRAQAVGLTPSGVLLAAFAEVLTAWSKSPKFTINLTLFNRLPLHPQVNEIVGDFTSVT 365 Query: 1552 CIRIHFQGITTFMELQDAVKHKVWSAMDKAQYPFDLLVEKVNPDRDLSRN---------P 1602 + ++ TF ++ ++W +D V V R+L+R P Sbjct: 366 LLEVNNSTSETFGNRALRLQQQLWQDLDHR------YVSGVEVMRELARRQGGTHRAMMP 419 Query: 1603 I-------YNVLFQFYDKLYLENE---GISPFELSCLAQETNQQIE---ISFEYNSDMYT 1649 + +N L + L E G+S L + +++ E +++ +D++ Sbjct: 420 VVFTSALTHNFLTNTANGLNQLGEIVYGVSQTPQVWLDHQVSEEEERLVFNWDVVADLFP 479 Query: 1650 DSTISRFAGYFLNIIGQVVDKPXXXXXXXXXXXXXXXXXXXSRFQGEQADLEDGQTIHGR 1709 + I + ++ ++ K + A G+ +H Sbjct: 480 EEMIDDMFETYCQLLVELATKEAVWQQPQRQLVPAYQLEQRAGVNQTPAP-NSGELLHTL 538 Query: 1710 FEAQVQKNPHAIALVYEEQQMTFQEVNGKANQLAWMLTGSGVQRNTPVGIFVDRSFSSVI 1769 F Q + H+ A++ E+ +T++E+ ANQ+ L G + N+ V + + + + V Sbjct: 539 FAKQAELRKHSPAVISPERVLTYEELWRLANQVGHRLQQLGAKPNSLVAVVISKGWKQVA 598 Query: 1770 GILAILKAGGAYVPLDPGYPEDRIAYILAHSGAKWLLTENRYLQSVAAFAHEEGIQIINL 1829 +L +L +G AYVP+DP P R +L S A+ ++T++ + + A G+ + L Sbjct: 599 AVLGVLMSGAAYVPIDPQLPSQRQQQLLEQSQARVIVTDDPLVATSAWV----GLIPVML 654 Query: 1830 SPVKEQSAVSQMYLADYEDELSRENPRTGGHGPDRMYIMYTSGSTGKPKGVLVTHSNVLN 1889 + QS + LA + P D Y++YTSGSTG PKGV + H + +N Sbjct: 655 IDERMQSQEPTLPLAWVQ------TPE------DLAYVIYTSGSTGIPKGVAIDHCSAVN 702 Query: 1890 FVTWSIGELQLQPKDALLLVTSISFDISVFEIFAALLSGSRLCIASMEHLKDTECLLAYM 1949 + + P D +L +++++FD+SV++IF L +G + + + +K+ + M Sbjct: 703 TLLDINSRFCVSPADRVLALSALNFDLSVYDIFGVLAAGGTIVMPGVTEVKEPAHWVELM 762 Query: 1950 EAQHITIWHSVPSLMVQLMTLLRHHPGRYRHSPVLQQLRHLMLGGEAWSTSLAASLRETF 2009 H+T+W++VP+L +L + R R +P Q LR +L G+ SL A LR+ + Sbjct: 763 RQHHVTLWNTVPALG----QMLADYLSRERMTPP-QGLRLALLSGDWLPLSLPAQLRQLW 817 Query: 2010 PQAEIRNMYGPTEATIWVSSYKPGPEIDESHPVMLIGRPIANNRLIILDQYGNVCPPGVA 2069 Q EI ++ G TEA+IW Y P E+D S + G+P+ N ++ D N P V Sbjct: 818 SQMEIVSLGGATEASIWSICY-PIDEVDPSWSSIPYGKPLVNQTFVVFDDRLNARPVWVP 876 Query: 2070 GEIYIAGNNVTQGYYNDEEKTRMAFIPQS-NGQIFYKTGDSGRYLPEGNVEFTGRRDQLV 2128 GE+YI G + +GY+ DEE+T +FI G+ YKTGD GRYLP GN+EF GR D + Sbjct: 877 GELYIGGIGLARGYWQDEERTATSFITHPVTGERLYKTGDLGRYLPNGNIEFLGRLDHQI 936 Query: 2129 KVRGYRIELGEIEQALKELTSLQQIAVTAVKDGETSKIVCLYT----------------- 2171 K+RG+RIELGEIE L + S+QQ VT+V + ++V Sbjct: 937 KIRGFRIELGEIESVLGQHPSVQQTLVTSVGESANRQLVAYVVPTIEHYPASPSEVHDPI 996 Query: 2172 -------GDQPVPQNQLKDAVRKRLPEYMIPAQFFHVERFLLTPNGKMDWRSMEKFVRET 2224 G Q + L++ ++++LP YM+P+ F +E LTPNGK+D +++ + Sbjct: 997 EFKLSQPGWQQIRIAHLREFLQEQLPAYMVPSHFVILEALPLTPNGKVDRKALPAPEMRS 1056 Query: 2225 PGSIEAAGIRNEVDKKLSEIWKKLLGIPAVGIQENFFDIGGNSLLVVQMQGMIQQEFFQD 2284 +E R +++ L+ IW +L + +GI +NFF++GGNSLL Q+ ++ + Sbjct: 1057 DQKLEFEAGRTPIEEMLTFIWANILKVEQIGIHDNFFELGGNSLLATQVIAQVRSTISLE 1116 Query: 2285 IPMMDLFKYTSIEKISDYLQ 2304 IP+ LF++ ++ K++ +Q Sbjct: 1117 IPLRSLFQHPTVAKLAQIIQ 1136 Score = 174 bits (441), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 104/362 (28%), Positives = 192/362 (53%), Gaps = 8/362 (2%) Query: 1169 TEIEQQIARIWGNLFQMPNIDIQDNFYELGGTSIMGIKIANRINEQYRVTMTIQDVFTHL 1228 T IE+ +A+IW + ++ + I DNF+ELGG S++ ++ +RI ++V + ++ +F Sbjct: 4257 TPIEEMLAQIWAQVLKVEQVGIYDNFFELGGHSLLATQLLSRIRNTFKVELPLRSLFAAA 4316 Query: 1229 TVASLGKLVEQ--KLGTKTEAGAVNKQEVEYAKTSMPLSHAQRRIWFLQKMNPDLVAYNL 1286 TVA L + +EQ + G + + + + V+ A+ + LS AQ+R+WFL ++ P+ YN+ Sbjct: 4317 TVAELAQEIEQLQQQGLELTSSPILPR-VDNAE--LLLSFAQQRLWFLDQLEPNSALYNI 4373 Query: 1287 PFIRYFDMAIDLELLQQAASFLAGRHLLMRTKYVLKDGNPVQ--EVLPAYVPAVQSIDAA 1344 P + ++ L+Q+ + RH +RT ++ +G P Q + ++ +V Sbjct: 4374 PLTLRIVGTLSVKALEQSLEEIIHRHEALRTNFITIEGKPSQIIQTQTNWIVSVVDYQHL 4433 Query: 1345 GQSDPELFVKMNIHQQKMKPFNLEMPPY-RIYLYTISDERACLYINFHHILTDGWSIDIY 1403 S+ E+ + +Q ++PF+L R L +S+ + L + HHI++DGWS ++ Sbjct: 4434 STSEQEIATQQLAQKQLIQPFDLTSEALVRATLIILSETKHILLVCMHHIVSDGWSTGVF 4493 Query: 1404 YRELFSLYQAFLHQQPPRLPEVKEDYFDWILEQKAWEESEAFVEHEQFWLKELAKPLPVL 1463 +EL LY A+ QP L + Y D+ + Q+ W + + +W ++L +L Sbjct: 4494 LQELAVLYNAYSQGQPSPLASLPIQYADFAIWQRNWLQGDVLQTQLNYWQQQLKDAPALL 4553 Query: 1464 SLPSDHKAPAVQTYRGSFHKFTISGELYRKLKAHLETQQITANNFLLSAYFLLLHNLSQE 1523 LP+D PAVQT+ G+ KF +S +L + L + Q +T LL+ Y LL+ + + Sbjct: 4554 VLPTDRPRPAVQTFAGTHQKFALSEKLTQGLIQLSKEQGVTLFMTLLATYDTLLYRYTGQ 4613 Query: 1524 QD 1525 D Sbjct: 4614 AD 4615 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.135 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 3,459,582,256 Number of extensions: 149155686 Number of successful extensions: 399522 Number of sequences better than 1.0e-05: 4998 Number of HSP's gapped: 379390 Number of HSP's successfully gapped: 7355 Length of query: 2331 Length of database: 757,237,578 Length adjustment: 142 Effective length of query: 2189 Effective length of database: 371,693,520 Effective search space: 813637115280 Effective search space used: 813637115280 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 134 (56.2 bits)