BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0013.p (1426 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_486686.1| polyketide synthase type I [Nostoc sp. PCC 7120... 589 e-166 ref|ZP_00110274.1| COG3321: Polyketide synthase modules and rela... 575 e-162 gb|AAF15892.2| NosB [Nostoc sp. GSV224] 569 e-160 ref|ZP_00110898.1| COG3321: Polyketide synthase modules and rela... 565 e-159 ref|ZP_00110270.1| COG3321: Polyketide synthase modules and rela... 557 e-157 >ref|NP_486686.1| polyketide synthase type I [Nostoc sp. PCC 7120] pir||AG2136 polyketide synthase type I [imported] - Nostoc sp. (strain PCC 7120) dbj|BAB74345.1| polyketide synthase type I [Nostoc sp. PCC 7120] Length = 1488 Score = 589 bits (1519), Expect = e-166, Method: Compositional matrix adjust. Identities = 304/650 (46%), Positives = 416/650 (64%), Gaps = 18/650 (2%) Query: 4 KIAIIGLACRVPGADTPAAFWHQIVNGVESIRTFKDEELTASGISADILNHPQYVKRGAV 63 +IAIIG+ + PGA+ +W + NGVESI DE++ +G+ L HP YVKR A+ Sbjct: 8 EIAIIGINGKFPGANNLEEYWQNLRNGVESITNLTDEQIQKNGVDPTQLKHPNYVKRQAI 67 Query: 64 IENADCFDAGFFRYTAKDAEITDPQHRAFLECAWEALEDAGCVQDLEKYPVGVYASSCIS 123 I+N + FDA FF + ++AEI DPQHR FLECAW ALEDAG + +GVYA + ++ Sbjct: 68 IDNIEYFDAEFFGFNPREAEILDPQHRLFLECAWTALEDAGYNPENYTGAIGVYAGAAMN 127 Query: 124 SYVLNLYSDPELMGRLGHVQIGIGNEKDFLASKVSYKLGLRGPSVNVQTACSSSLVAVHM 183 +Y+LNL ++P++ ++ Q+ + N+KDFL ++VSYKL LRGPS+++QTACS+SLVAVH+ Sbjct: 128 NYLLNLITNPQIQNQISRYQLFLSNDKDFLTTRVSYKLNLRGPSLDIQTACSTSLVAVHV 187 Query: 184 ASQSLLNGECDLALAGGVTIRSEQRAGYMYQKEGMVSPDGHCRVFDKDSKGTVFGNGLGI 243 A QSLL+GECD+ALAGGV++ + GY+YQ+ G+ SPDGHCR FD D++GT+ G+GLGI Sbjct: 188 ACQSLLSGECDIALAGGVSL--AKATGYLYQEGGIYSPDGHCRAFDADAQGTIAGSGLGI 245 Query: 244 VVLKRLADAVRDRDNIQAVICGTAVNNDGDHKIGFTAPSPVGQAQVIHEALSVAGVAPRE 303 VVLKRL +A+ DRD I AVI G+A+NNDG K+ +TAP QA VI A ++AGV P + Sbjct: 246 VVLKRLQEAIEDRDYIHAVIKGSAINNDGGLKVSYTAPRIDTQAAVIRAAQALAGVEPAD 305 Query: 304 ISYIETHGTGTELGDAIEIKALKEVFQAETGPAQFCAIGSVKPNIGHLDTAAGIIGLIKT 363 ISYIETHGTGT LGD IEI AL + F+A T FCAI SVK NIGHLD AAGI LIKT Sbjct: 306 ISYIETHGTGTALGDPIEIAALTQAFRAGTEKTGFCAISSVKTNIGHLDAAAGIASLIKT 365 Query: 364 TLAMKNQVIPVCINHETPDPKLSLEDSPFYVNTASRPWKEVSAAPKAGVSSFGIGGTNAH 423 LA+K+Q IP ++ + P+P++ +PFYVNT W+ +AGVSSFGIGGTNAH Sbjct: 366 VLALKHQQIPPNLHFQQPNPQIDFSQTPFYVNTNLVDWETDKTPRRAGVSSFGIGGTNAH 425 Query: 424 IILEEAP---SIASDASAKQNHVFLFSAKTLKSLEDTCRNMADFFGNHSTLHPADVAYTL 480 +ILEEAP I + + SAK+ K+LE+ N+A + H + AD+AYTL Sbjct: 426 VILEEAPIKFKIQNSKFKINYQMLCLSAKSEKALEEATINLATYLQQHPQFNLADIAYTL 485 Query: 481 QTGRKHFPYRKMVVSSSLEEAAQWLRTGSSQTECKGREEVPVAFFFPAEQRDMLRIGYEL 540 GR+HF YR+MV+ + EEAAQ L + T + +AF FP + L +G EL Sbjct: 486 HIGRQHFAYRRMVLCQTTEEAAQILEKETKYTHTNSEKSPSIAFMFPGQGSHYLNMGKEL 545 Query: 541 YQKETRFASIIDTYLSNERILHTLAGLDLQQILAGSR----------HGNQERLYTVLGQ 590 Y+ E F ID E + H L GLDL IL + + +Y Sbjct: 546 YETEAIFREQIDH--CCELLQHDL-GLDLLSILFETESIPSPQSPVPSPQSQTIYAQPAL 602 Query: 591 FIYQCALADYLVTLGIRKEVLIAEGNGVLPAVYVSGALSMNDLIRIILIR 640 FI + ALA ++ GI+ + +I G ++G S+ D+++++ +R Sbjct: 603 FIIEYALAKLWISWGIQPQAMIGHSLGEYVVATLAGVFSLPDVLKLVALR 652 Score = 218 bits (556), Expect = 7e-55, Method: Compositional matrix adjust. Identities = 171/727 (23%), Positives = 332/727 (45%), Gaps = 71/727 (9%) Query: 651 QSLLAIELASLLKILPVQTPEAEMLAG--GLRVSEEMLRDEEFWLSC--GPASDWPQAPS 706 +S++ +A+ KI +QTP+ ++ G ++ E D +W++ P Sbjct: 731 ESMITPFIAAFQKI-TLQTPKIPFISNVTGTWITAEQATDPHYWVNHLRQPVQFATGIKE 789 Query: 707 LPEQENRLLIKIG----MESGTDGALKGMGVVSLLRQQAYDEPADFIFY-SKLGEIWTEG 761 L + ++L+++G + + ++S LR D +D F LG++W G Sbjct: 790 LLTEPQQILLEVGAGRTLATLAKQQTNSHTILSSLRH-PQDTQSDVAFLLQTLGQLWLAG 848 Query: 762 GTVDWQPFYFQESRKRVTLPAYAFDRQRYWHERK--EQAPQTVPRKKTPEQWLYRPVWKQ 819 ++DW+ FY + R+R+ LP Y F RQRYW + K EQ + +P + LY P W++ Sbjct: 849 VSIDWENFYTHQQRQRLPLPTYPFQRQRYWIDLKAGEQGSENIPSPR-----LYLPSWER 903 Query: 820 YYASPDYRLEDRGPDTFLLFIDDSGLGEGIQEALSAKGNRVCTVKMGAGFGRIHRDQYEI 879 P + ++ +L+F D+ G+ + I L A G+ V V G + + + + Sbjct: 904 SLPHPQVDIAEKRL-CWLVFTDNYGIYQEIINTLQAVGHDVIIVSQGEKYDQPAYRTFTV 962 Query: 880 DPDNAEHYLQVFRQVFQTGHPVWKIVHMWSSREYMPDSGGFYSLLHMGKSFGMIGIHQQI 939 +P N++ +++++ + I+++W + SLL++ ++ I ++I Sbjct: 963 NPQNSQDFVELWSDLELRELIPHHILYLWDLTDLQQQP---LSLLYLAQAISSQSIEREI 1019 Query: 940 QLTVVTSAFQSVMGNEVLTPSNAAATGAVHVIQQELQNVRTALIELAGEDTGKYDQAALE 999 LT+VT+ Q ++GNE + P A G VI QE+ + ++++ ++ + Sbjct: 1020 TLTLVTNDGQLLLGNENIQPMKATVWGMGKVISQEIPQLTCRCVDISLSTVASTNEQIAQ 1079 Query: 1000 LLLEEFIKPGPERFLAVRGRRKWVRAFEPMQMDHPADLKQKRDGVHVIXXXXXXXXXXXX 1059 L+ E + + +A RG +W + ++P+ MD Q + VH Sbjct: 1080 QLITECLNNQNDSVVAYRGNYRWNQIYKPLLMDD----AQSKISVH-------------- 1121 Query: 1060 XXXXEQGAGTLIL----TGRTSFPPEAEWQERLALYPGNDIINQKIRKIIELQEQGAQVY 1115 +G +IL TG + E + + L +D+I + +++ L G Sbjct: 1122 -----EGGNYVILGDLTTGLGTVFAEFLMKNSVRLVLLSDVITETLKQ--SLDNVGIDYL 1174 Query: 1116 LYQVQVSDEKRMNGLFTSIEHTHGKIQGVIYSAGTVVSDFFHNSISGITREMCEAEFEAK 1175 + ++ + + E G+I GV YS + ++ + +T + E + K Sbjct: 1175 SLNIDITKQAELENAIAQAETKFGQINGVFYST-PMSNEHSMAFLPQLTTKHWEYNYRTK 1233 Query: 1176 IRGLIILERMIRGKDIEYCMVNSSISTILGGIGLAAYTAANQFMDSFVQMMNQQQNRTRW 1235 I+GL +L ++R K +++C++ SS+ST+LGG+GLA Y AAN +D F N Q ++ W Sbjct: 1234 IQGLCVLAEVLRDKPLDFCVLQSSLSTVLGGLGLAVYAAANAVIDMFAIQQN-QNSKFPW 1292 Query: 1236 MAVDWDAWNFSASDKAGGTAANERLDQFIHPAEGGAVIKALFQVMNKTEHIVVSTTELEP 1295 ++++WDA + A + + PAE + + + + E +VV+ ++L+ Sbjct: 1293 ISINWDACRSDLETDINHSFAANLVTLALTPAEVWQSTQHIIK-LGLPESVVVTKSDLDK 1351 Query: 1296 RLALWVNHSRNNEPGSQRESRKELSIEQLLQERI--------------REATGLSGMGAD 1341 RL WV N ++ E+ + QL E I ++ G+S +G + Sbjct: 1352 RLEKWVT---NTPTKTKTETNNSYTRPQLTNEYIAPRDEIETAIAQIWQDLLGISPIGIN 1408 Query: 1342 ENFFDAG 1348 ++FFD G Sbjct: 1409 DSFFDLG 1415 >ref|ZP_00110274.1| COG3321: Polyketide synthase modules and related proteins [Nostoc punctiforme] Length = 1626 Score = 575 bits (1481), Expect = e-162, Method: Compositional matrix adjust. Identities = 310/655 (47%), Positives = 415/655 (63%), Gaps = 27/655 (4%) Query: 4 KIAIIGLACRVPGADTPAAFWHQIVNGVESIRTFKDEELTASGISADILNHPQYVKRGAV 63 +IAI+G+ R P A FW + +GVESI F DEEL +S I L+ PQYVK G+V Sbjct: 13 EIAIVGMNGRFPRAKNIEQFWQNLRDGVESISFFSDEELLSSRIDPATLSQPQYVKAGSV 72 Query: 64 IENADCFDAGFFRYTAKDAEITDPQHRAFLECAWEALEDAGCVQDLEKYPVGVYASSCIS 123 +E+ + FDA FF ++AK+A+ITDPQHR FLECAWEALE AG ++ +GVYA + ++ Sbjct: 73 LEDIELFDASFFDFSAKEAQITDPQHRLFLECAWEALESAGYNSEIYAGRIGVYAGASLN 132 Query: 124 SYVL-NLYSDPELMGRLGHVQIGIGNEKDFLASKVSYKLGLRGPSVNVQTACSSSLVAVH 182 +Y L NLY+ P+++ +G +I IGN +FL + VSYKL L+GPS+NVQTACS+SLVAVH Sbjct: 133 TYFLTNLYTQPKIIESVGSYRISIGNSPNFLPTYVSYKLNLKGPSLNVQTACSTSLVAVH 192 Query: 183 MASQSLLNGECDLALAGGVTIRSEQRAGYMYQKEGMVSPDGHCRVFDKDSKGTVFGNGLG 242 +A QSLLNGE D+ALAGGV+I+ + GY YQ+ G++SPDGHCR FD ++G + GNG+G Sbjct: 193 LACQSLLNGESDIALAGGVSIQVPHKTGYRYQQGGIMSPDGHCRAFDAKAQGIISGNGVG 252 Query: 243 IVVLKRLADAVRDRDNIQAVICGTAVNNDGDHKIGFTAPSPVGQAQVIHEALSVAGVAPR 302 IVVLKRL DA+ D D I AVI G+A+NNDG K+GFTAPS GQA+VI EAL++A V Sbjct: 253 IVVLKRLEDALADGDCIHAVIKGSAINNDGSLKVGFTAPSVDGQAKVIAEALAMARVESE 312 Query: 303 EISYIETHGTGTELGDAIEIKALKEVFQAETGPAQFCAIGSVKPNIGHLDTAAGIIGLIK 362 ISY+ETHGTGT LGD IEI +L + F+ T FCAI SVK NIGHLD AAG+ GLIK Sbjct: 313 TISYVETHGTGTVLGDPIEIASLTQAFRP-TDKKNFCAIASVKTNIGHLDAAAGVAGLIK 371 Query: 363 TTLAMKNQVIPVCINHETPDPKLSLEDSPFYVNTASRPWKEVSAAPKAGVSSFGIGGTNA 422 T LA+K+Q IP ++ E P+P++ +SPFYVN WK +AGVSSFGIGGTNA Sbjct: 372 TVLALKHQQIPPSLHFEQPNPQIDFANSPFYVNDKLSEWKSNGTPRRAGVSSFGIGGTNA 431 Query: 423 HIILEEAPSIASDASAKQN---HVFLFSAKTLKSLEDTCRNMADFFGNHSTLHPADVAYT 479 H+ILEEAP +Q H+ + SAKT +LE N+A+ H L+ AD+AYT Sbjct: 432 HVILEEAPVWEQGRQRRQGRKYHLLVISAKTKSALETATANLANHLKQHLELNLADIAYT 491 Query: 480 LQTGRKHFPYRKMVVSSSLEEAAQWLRTGSSQ------TECKGREEVPVAFFFPAEQRDM 533 L GR+ F R+++V +L +A L T S+ TE G++ +AF FP + Sbjct: 492 LGVGRRGFSDRRILVCQNLNDAVTVLETPVSERVFTKFTEPSGQQ---IAFMFPGQGTQY 548 Query: 534 LRIGYELYQKETRFASIIDTYLSNERILHTLAGLDLQQILAGSRHGNQERLYTVLGQ--- 590 + +G ELY+ E F +D L + LDL+ +L H E L L Q Sbjct: 549 VNMGRELYETEIIFRKQVDYCC---EFLKSYLKLDLRTLL--YPHQQTEALTQQLQQTHI 603 Query: 591 -----FIYQCALADYLVTLGIRKEVLIAEGNGVLPAVYVSGALSMNDLIRIILIR 640 F+ + ALA + G+R +I G A ++G S+ + + ++ R Sbjct: 604 TQSAVFVVEYALAQLWMAWGVRPNAMIGHSIGEYVAACIAGVFSLEEALILVANR 658 Score = 58.9 bits (141), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 32/93 (34%), Positives = 47/93 (50%), Gaps = 7/93 (7%) Query: 707 LPEQENRLLIKIG------MESGTDGALKGMGVVSLLRQQAYDEPADFIFYSKLGEIWTE 760 L +Q R+L+++G + A + + + SL Q F+ + LG +W E Sbjct: 796 LLQQPKRILLEVGPGRTLSTLANKQKAAQQVILSSLRHPQNQQSDVAFLL-NTLGRLWLE 854 Query: 761 GGTVDWQPFYFQESRKRVTLPAYAFDRQRYWHE 793 G VDW FY E R R+ LP Y F+R+RYW E Sbjct: 855 GINVDWSEFYADEERHRIPLPTYPFERKRYWIE 887 >gb|AAF15892.2| NosB [Nostoc sp. GSV224] Length = 1244 Score = 569 bits (1467), Expect = e-160, Method: Compositional matrix adjust. Identities = 302/654 (46%), Positives = 411/654 (62%), Gaps = 19/654 (2%) Query: 3 SKIAIIGLACRVPGADTPAAFWHQIVNGVESIRTFKDEELTASGISADILNHPQYVKRGA 62 S+IAII LA R P A +FW + +GVESI DEEL SG+S D+LN+P YVK A Sbjct: 13 SEIAIISLAGRFPKAKDIDSFWQNLYDGVESISRLTDEELITSGVSLDLLNNPNYVKASA 72 Query: 63 VIENADCFDAGFFRYTAKDAEITDPQHRAFLECAWEALEDAGCVQDLEKYPVGVYASSCI 122 V+ + + FDA FF Y+AK+AE+ DPQ R FLE AWEA+E AG +GVYA + Sbjct: 73 VLSDIELFDANFFAYSAKEAELIDPQQRLFLELAWEAIEKAGYDPHTYNGLIGVYAGVGM 132 Query: 123 SSYVLN-LYSDPELMGRLGHVQIGIGNEKDFLASKVSYKLGLRGPSVNVQTACSSSLVAV 181 + Y++N LY +L+ + +Q+ I N+KDFL ++V+YKL L G +VNVQTACS+SLVAV Sbjct: 133 NRYLVNNLYPHHQLLETVDPLQLTISNDKDFLPTRVAYKLNLTGTAVNVQTACSTSLVAV 192 Query: 182 HMASQSLLNGECDLALAGGVTIRSEQRAGYMYQKEGMVSPDGHCRVFDKDSKGTVFGNGL 241 H+A QSLLN ECD+ALAGGVT+ Q+ GY++Q+ ++SPDGHCR FD ++GT+ +G Sbjct: 193 HLACQSLLNYECDMALAGGVTLSIPQKIGYLHQEGMILSPDGHCRAFDAKAQGTIASSGA 252 Query: 242 GIVVLKRLADAVRDRDNIQAVICGTAVNNDGDHKIGFTAPSPVGQAQVIHEALSVAGVAP 301 GIVVLKRL DA+ DRD+I A+I G+A+NNDG K+GFTAPS GQA VI EA ++AGV Sbjct: 253 GIVVLKRLKDAIADRDHIHAIIKGSAINNDGAMKVGFTAPSVSGQAAVIAEAQAIAGVDA 312 Query: 302 REISYIETHGTGTELGDAIEIKALKEVFQAETGPAQFCAIGSVKPNIGHLDTAAGIIGLI 361 ISYIE HGT T LGD IEI AL + F T FCAIGS+K N+GHLDTAAG+ GLI Sbjct: 313 ETISYIEAHGTATPLGDPIEIAALTQAFSQTTDKKGFCAIGSLKTNLGHLDTAAGVAGLI 372 Query: 362 KTTLAMKNQVIPVCINHETPDPKLSLEDSPFYVNTASRPWKEVSAAPKAGVSSFGIGGTN 421 KT LA++N+++P ++ ETP+PK+ +SPFYVNT W+ + +AGVSSFGIGGTN Sbjct: 373 KTVLALQNKMLPPSLHFETPNPKIDFANSPFYVNTTLTEWRTNTTPRRAGVSSFGIGGTN 432 Query: 422 AHIILEEAP-----SIASDASAKQNHVFLFSAKTLKSLEDTCRNMADFFGNHSTLHPADV 476 AH+ILEEAP S + + + + SAKT +LE N+ H L DV Sbjct: 433 AHVILEEAPMFEQGSRGAGEQGRNYQLLVLSAKTASALEKATANLITHLKEHPELDLGDV 492 Query: 477 AYTLQTGRKHFPYRKMVVSSSLEEAAQWLRTGSSQTECKGREEV---PVAFFFPAEQRDM 533 AYTL +GR+ F YR+M++ LE+A + L + +Q E+ V F FP + Sbjct: 493 AYTLNSGRRGFNYRRMLICQDLEDAVKTLSSLEAQQVFSNYTEITERSVVFMFPGQGSQY 552 Query: 534 LRIGYELYQKETRFASIIDTYLSNERILHTLAGLDLQQILAGSR----HGNQERLYTVLG 589 + + E+YQ ET F +D Y S +L L G+DL+ IL S +++ T + Sbjct: 553 VNMAREIYQTETVFKEQVD-YCS--EVLKPLLGIDLRHILYPSEEKIDEASKQLQQTAVA 609 Query: 590 Q---FIYQCALADYLVTLGIRKEVLIAEGNGVLPAVYVSGALSMNDLIRIILIR 640 Q F+ + AL + G++ + I G A ++ S+ D + ++ R Sbjct: 610 QPAIFVIEYALPKLWQSYGVQPQAAIGHSIGEYVAATLAEVFSLEDALSLVAAR 663 >ref|ZP_00110898.1| COG3321: Polyketide synthase modules and related proteins [Nostoc punctiforme] Length = 1258 Score = 565 bits (1455), Expect = e-159, Method: Compositional matrix adjust. Identities = 305/671 (45%), Positives = 416/671 (61%), Gaps = 34/671 (5%) Query: 1 MQSKIAIIGLACRVPGADTPAAFWHQIVNGVESIRTFKDEELTASGISADILNHPQYVKR 60 ++IAII LA R P A +FW + +GVESI DEEL SG+S D+LN+P YVK Sbjct: 10 FNNEIAIISLAGRFPEAKYLDSFWQNLRDGVESISRLTDEELINSGVSLDLLNNPNYVKA 69 Query: 61 GAVIENADCFDAGFFRYTAKDAEITDPQHRAFLECAWEALEDAGCVQDLEKYPVGVYASS 120 AV+ + + FDA FF Y+AK+AE+ DPQ R FLE AWEA+E AG +GVYA Sbjct: 70 NAVLSDIELFDANFFAYSAKEAELIDPQQRLFLELAWEAIEKAGYDPHTYNGLIGVYAGV 129 Query: 121 CISSYVLN-LYSDPELMGRLGHVQIGIGNEKDFLASKVSYKLGLRGPSVNVQTACSSSLV 179 ++ Y++N LY +L+ + +Q+ I N+KDFL ++V+YKL L G +VNVQTACS+SLV Sbjct: 130 GMNRYLVNNLYPHHQLLETVDPLQLTISNDKDFLPTRVAYKLNLTGTAVNVQTACSTSLV 189 Query: 180 AVHMASQSLLNGECDLALAGGVTIRSEQRAGYMYQKEGMVSPDGHCRVFDKDSKGTVFGN 239 AVH+A QSLLN ECD+ALAGGVT+ Q+ GY++Q+ ++SPDGHCR FD ++GT+ + Sbjct: 190 AVHLACQSLLNCECDMALAGGVTLSIPQKIGYLHQEGMILSPDGHCRAFDAKAQGTIASS 249 Query: 240 GLGIVVLKRLADAVRDRDNIQAVICGTAVNNDGDHKIGFTAPSPVGQAQVIHEALSVAGV 299 G GIVVLKRL DA+ DRD+I A+I G+A+NNDG K+GFTAPS GQA VI EA ++AGV Sbjct: 250 GAGIVVLKRLKDAIADRDHIHAIIKGSAINNDGAMKVGFTAPSVSGQAAVIGEAQAIAGV 309 Query: 300 APREISYIETHGTGTELGDAIEIKALKEVFQAETGPAQFCAIGSVKPNIGHLDTAAGIIG 359 ISYIE HGT T LGD IEI AL + F T FCAIGS+K N+GHLDTAAG+ G Sbjct: 310 DAETISYIEAHGTATPLGDPIEIAALTQAFNQSTDKKGFCAIGSLKTNLGHLDTAAGVAG 369 Query: 360 LIKTTLAMKNQVIPVCINHETPDPKLSLEDSPFYVNTASRPWKEVSAAPKAGVSSFGIGG 419 LIKT LA+++Q++P ++ ETP+PK+ +SPFYVNT WK + +AGVSSFGIGG Sbjct: 370 LIKTVLALQHQMLPPSLHFETPNPKIDFANSPFYVNTTLTEWKTNNTPRRAGVSSFGIGG 429 Query: 420 TNAHIILEEAPSI---ASDASA-----------------KQNHVFLFSAKTLKSLEDTCR 459 TNAH+ILEEAP + + SA + + + SAKT +LE Sbjct: 430 TNAHVILEEAPVFEQGSREGSAVLGVPPRSNCRRAGEQGRNYQLLVLSAKTASALEQATA 489 Query: 460 NMADFFGNHSTLHPADVAYTLQTGRKHFPYRKMVVSSSLEEAAQWLRTGSSQTECKGREE 519 N+ H L+ +DVAYTL +GR+ F YR+M++ LE+A + L + +Q E Sbjct: 490 NLITHLKEHPELNLSDVAYTLNSGRRGFNYRRMLICQDLEDAVKTLSSLEAQQVFSNYTE 549 Query: 520 V---PVAFFFPAEQRDMLRIGYELYQKETRFASIIDTYLSNERILHTLAGLDLQQILAGS 576 + V F FP + + + E+Y+ ET F ID Y S +L L GLDL+ IL S Sbjct: 550 ITERSVVFMFPGQGSQYVNMAREIYETETVFKEQID-YCS--EVLKPLLGLDLRHILYPS 606 Query: 577 ----RHGNQERLYTVLGQ---FIYQCALADYLVTLGIRKEVLIAEGNGVLPAVYVSGALS 629 +++ T + Q F+ + ALA + G+ + I G A ++ S Sbjct: 607 EEKIHEASKQLQQTAVAQPAIFVIEYALAKLWQSYGVEPQAAIGHSIGEYVAATLAEVFS 666 Query: 630 MNDLIRIILIR 640 + D++ ++ R Sbjct: 667 LEDVLSLVAAR 677 >ref|ZP_00110270.1| COG3321: Polyketide synthase modules and related proteins [Nostoc punctiforme] Length = 1959 Score = 557 bits (1436), Expect = e-157, Method: Compositional matrix adjust. Identities = 309/655 (47%), Positives = 413/655 (63%), Gaps = 22/655 (3%) Query: 3 SKIAIIGLACRVPGADTPAAFWHQIVNGVESIRTFKDEELTASGISADILNHPQYVKRGA 62 S+IAIIG+A + PGA FW + GVESI F DEEL ASGI A L +P++VK A Sbjct: 13 SEIAIIGIAGKFPGAKNTDEFWQNLQRGVESISVFTDEELLASGIDAATLKNPKFVKARA 72 Query: 63 VIENADCFDAGFFRYTAKDAEITDPQHRAFLECAWEALEDAGCVQDLEKY--PVGVYASS 120 V+E+ + FDA FF + ++A+ITDPQHR FLECA+ ALEDAG D E Y +GVYA + Sbjct: 73 VLEDVELFDASFFGFNPREADITDPQHRLFLECAYIALEDAGY--DSENYQGSIGVYAGA 130 Query: 121 CISSYVLNLYSDPELMGRLGHVQIGIGNEKDFLASKVSYKLGLRGPSVNVQTACSSSLVA 180 S Y+LN+Y + +++ + + Q+ I +KD+L ++VSYKL L GPS VQTACS+SLVA Sbjct: 131 SFSGYLLNVYLNEDIIKSIDYHQLAIAGDKDYLTTRVSYKLNLEGPSYTVQTACSTSLVA 190 Query: 181 VHMASQSLLNGECDLALAGGVTIRSEQRAGYMYQKEGMVSPDGHCRVFDKDSKGTVFGNG 240 VH+A+QSLLNGECD+ALAGGV+I S + GY+Y++ G+ SPDGHCR FD ++GTV G G Sbjct: 191 VHLAAQSLLNGECDMALAGGVSINSSGKTGYLYKEGGIGSPDGHCRAFDAQAQGTVGGEG 250 Query: 241 LGIVVLKRLADAVRDRDNIQAVICGTAVNNDGDHKIGFTAPSPVGQAQVIHEALSVAGVA 300 +GIVVLKRL DA+ D D I A+I G+AVNNDG K+ +TAP GQA+VI A VA V Sbjct: 251 VGIVVLKRLDDALADGDTIHAIIKGSAVNNDGSFKVSYTAPRIDGQAKVIRTAQVVAEVE 310 Query: 301 PREISYIETHGTGTELGDAIEIKALKEVFQAETGPAQFCAIGSVKPNIGHLDTAAGIIGL 360 P I+YIE HGTGT LGD IEI AL + F+A T FCAIGSVK NIGHLD AAG+ GL Sbjct: 311 PETITYIEAHGTGTSLGDPIEIAALTQAFRATTEKKGFCAIGSVKTNIGHLDAAAGVTGL 370 Query: 361 IKTTLAMKNQVIPVCINHETPDPKLSLEDSPFYVNTASRPWKEVSAAPKAGVSSFGIGGT 420 IKT LA+K+Q IP ++ + P+P++ +SPFYVNT W +AGVSSFGIGGT Sbjct: 371 IKTVLALKHQQIPPSLHFQQPNPQIDFANSPFYVNTTLTEWTTNGIPRRAGVSSFGIGGT 430 Query: 421 NAHIILEEAP-----SIASDASAKQNHVFLFSAKTLKSLEDTCRNMADFFGNHSTLHPAD 475 NAH+ILEEAP S + ++ H+ + SAKT +LE N+A+ H L+ AD Sbjct: 431 NAHVILEEAPAKEQGSRGAGEQGRKYHLLVLSAKTESALETATANLANHLKQHPNLNLAD 490 Query: 476 VAYTLQTGRKHFPYRKMVVSSSLEEAAQWLRTGSSQ---TECKGREEVPVAFFFPAEQRD 532 VA+TL GR+ F +R++VV + +A + L T SQ T + PV F F + Sbjct: 491 VAHTLGIGRRAFDHRRIVVCQDMNDAVKVLSTSDSQRVFTHYQQPCHRPVVFMFSGQGTQ 550 Query: 533 MLRIGYELYQKETRFASIIDTYLSNERILHTLAGLDLQQIL----AGSRHGNQERLYTVL 588 + + ELY E F +D+ +L G DL+ +L A + E T + Sbjct: 551 YVNMARELYGSEPIFTLTVDSCC---ELLQPHLGFDLRHVLYPDEAQNAKATLELQQTSV 607 Query: 589 GQ---FIYQCALADYLVTLGIRKEVLIAEGNGVLPAVYVSGALSMNDLIRIILIR 640 Q F+ + ALA + G++ E +I G A ++G S+ D + ++ IR Sbjct: 608 AQPALFVIEYALAQLWMAWGVQPEAMIGHSIGEYVAATLAGVFSLEDALMLVAIR 662 Score = 187 bits (476), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 154/631 (24%), Positives = 288/631 (45%), Gaps = 47/631 (7%) Query: 795 KEQAPQTVPRKKTPEQWLYRPVWKQYYASPDYR--LEDRGPDTFLLFIDDSGLGEGIQEA 852 KEQ + +K W Y P WK+ ++ P +L+F+D+ GLGE + + Sbjct: 1296 KEQYQDLLSKKPDIADWFYIPSWKRTMPPQPFQPGFGITQPGCWLVFVDEFGLGERLVKQ 1355 Query: 853 LSAKGNRVCTVKMGAGF---GRIHRDQYEIDPDNAEHYLQVFRQVFQTGHPVWKIVHMWS 909 L + V TVK+G F + Y I+P+ + Y + + + G +IVH+WS Sbjct: 1356 LVLENQDVITVKVGEQFQQSSEYSQYTYTINPEKEDDYNTLLKGLRTLGKIPRRIVHLWS 1415 Query: 910 --SREYMP---DSGGFYSLLHMG------KSFGMIGIHQQ---IQLTVVTSAFQSVMGNE 955 S Y ++ G+ SLL +G K+ + + Q +++ +V++ Q V G+E Sbjct: 1416 VTSNSYTNSAIEALGWSSLLFLGQAMSDDKALRVYAENNQTDAVEIAIVSNNLQEVTGSE 1475 Query: 956 VLTPSNAAATGAVHVIQQELQNVRTALIELAGEDTGKYDQAALELLLEEFIKPGPERFLA 1015 +L P A GA V+ E N+ I++ ++ ++ ++ L+ E ++ +A Sbjct: 1476 MLCPEKALVLGACKVMPLEYANINCRSIDVVIPESESGEEQLIKALIAELTTYTSDQVIA 1535 Query: 1016 VRGRRKWVRAFEPMQMDHPADLKQKRD-GVHVIXXXXXXXXXXXXXXXXEQGAGTLILTG 1074 RGR +WV+ FEP+Q+ R+ GV++I + LIL G Sbjct: 1536 YRGRNRWVQDFEPVQLHGTVAGNLLREQGVYLITGGLGGVGLLLAEYLAQTVQAKLILLG 1595 Query: 1075 RTSFPPEAEWQERLALYPGNDIINQKIRKIIELQEQGAQVYLYQVQVSDEKRMNGLFTSI 1134 R++FP + +W E L+ + +D I+QKI+K+ ++ GA+V + V++ ++M+ + Sbjct: 1596 RSAFPDQDKWSEWLSTHDRHDSISQKIQKLQAMKTLGAEVMVVSTDVTNLEQMSAVLKKA 1655 Query: 1135 EHTHGKIQGVIYSAGTVVSDFFHNSISGITREMCEAEFEAKIRGLIILERMIRGKDIEYC 1194 G+I GVI++A + T+E + K++G +LE + + +++ Sbjct: 1656 NQRFGEIHGVIHAAAVYGGGMMQLA----TKETVASAIAPKVQGTRVLETLFQESKLDFF 1711 Query: 1195 MVNSSISTILGGIGLAAYTAANQFMDSFVQMMNQQQNRTRWM-AVDWDAWN--------- 1244 ++ SS+S+ G G+ YTAAN F+DSF Q + +++ +++WD WN Sbjct: 1712 VLCSSLSSFAGTSGMVDYTAANAFLDSFAQYSAAKYGTWKFIKSINWDRWNNVGMAVPVE 1771 Query: 1245 -----FSASDKAGGTAANERLDQFIHPAEGGAVIKAL-----FQVMNKTEHIVVSTTELE 1294 + + G A E ++ F V + + F + K + V S E Sbjct: 1772 ARHQQITGKELIAGMTAFEGIEAFKRILCSSTVPQVIISTQDFLSLIKPKESVESLEEKL 1831 Query: 1295 PRLALW-VNHSRNNEPGSQRESRKELSIEQLLQERIREATGLSGMGADENFFDAGITSID 1353 +L+ + H R N + E IE+ L + ++ G+ +G +NFF+ G S+ Sbjct: 1832 AQLSQYKSTHPRPNLANTYVAPNNE--IERNLADIWQQILGIEKVGIHDNFFELGGDSLF 1889 Query: 1354 IVGMNDSIQQHINRPILISSWYEYPTIKKLA 1384 + + + + ++ PT+ LA Sbjct: 1890 ATQLVSQLCKVFQIELSYKGFFNGPTVADLA 1920 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.318 0.135 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 2,134,098,517 Number of extensions: 91403431 Number of successful extensions: 216202 Number of sequences better than 1.0e-05: 2026 Number of HSP's gapped: 207979 Number of HSP's successfully gapped: 2549 Length of query: 1426 Length of database: 757,237,578 Length adjustment: 138 Effective length of query: 1288 Effective length of database: 382,553,916 Effective search space: 492729443808 Effective search space used: 492729443808 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 132 (55.5 bits)