BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0005.p (541 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value dbj|BAB69698.1| iturin A synthetase A [Bacillus subtilis] 384 e-105 emb|CAE11250.1| BmyA protein [Bacillus amyloliquefaciens] 383 e-105 pir||T44806 mycosubtilin synthetase chain mycA [imported] - Baci... 374 e-102 ref|ZP_00107678.1| COG1020: Non-ribosomal peptide synthetase mod... 359 1e-97 ref|ZP_00074380.1| COG3321: Polyketide synthase modules and rela... 346 1e-93 >dbj|BAB69698.1| iturin A synthetase A [Bacillus subtilis] Length = 3982 Score = 384 bits (985), Expect = e-105, Method: Compositional matrix adjust. Identities = 211/476 (44%), Positives = 288/476 (60%), Gaps = 26/476 (5%) Query: 14 LTGSYTGILSSRISYFLDLKGPSIVLDSACSSGLLAIHDACQAIRNNECDMAIAGGVCLI 73 + G+ +L+SRI+YFL+LKGP++ +D+ACSS L A+H AC+++ + +C+MA+AGG+ Sbjct: 813 IVGNLPSVLASRIAYFLNLKGPAVTVDTACSSSLAAVHMACKSLMSGDCEMALAGGIRTS 872 Query: 74 FFPMKNPAFGL-VESKLQLLKPFDKQADGTLWGEGIGSLLLKPLDKAVEDRDPIHAVIKG 132 P+ GL +ES K F K +DGT GEG ++LLKPL AV D D I+ VIKG Sbjct: 873 LLPI---CIGLDMESSDGYTKTFSKDSDGTGTGEGAAAVLLKPLQDAVRDGDHIYGVIKG 929 Query: 133 SAVNNDGRSNGLTAPNALAQEDLFTQAWINAEIAPETIGFYEAHGTGTVLGDPIEVQSLS 192 SA+N DG + G+TAPN AQ ++ AW +A IAPET+ F EAHGTGT LGDP+E L Sbjct: 930 SAMNQDGTTAGITAPNPAAQTEVIETAWKDAGIAPETLSFIEAHGTGTKLGDPVEFNGLC 989 Query: 193 NAFRKYTSKKQFCGIGSVKSNIGHLAAASGIASVMKTILSLKHQKLVSTLHFDDPNPFID 252 AF KYT+KKQFC IGSVKSNIGHL A+GI ++K++L L H+K HF++PNP I Sbjct: 990 KAFEKYTAKKQFCAIGSVKSNIGHLFEAAGIVGLIKSVLMLNHKKNPPLAHFNEPNPLIH 1049 Query: 253 FVGSPVYMVNKQQEWKRAQEDIPLRAGISSFGFSGTNLHLVLEEAPVSPKLAPASR--PY 310 F SP Y+ + E+ E PLR G+SSFGFSGTN H+VLEE + AP P Sbjct: 1050 FHSSPFYVNQEAAEFTSGDE--PLRGGVSSFGFSGTNAHVVLEEYISQSEYAPEDEHGP- 1106 Query: 311 HIFTVSAKEKTVLAEWVSRYLQHMQRAGDIELADLCYTAATGRGHYAYRLALIVRDIQEL 370 H+F +SA + L E +Y Q++ L +CYTA+TGR H + +A+IV QEL Sbjct: 1107 HLFVLSAHTEKSLYELAQQYRQYVSDDSQASLKSICYTASTGRAHLDHGIAMIVSGKQEL 1166 Query: 371 QEKLHRIIQEHPITGHTEDGIYYGEFKIVPESKKYKSTGEITESGLNLLHEQARAALGA- 429 +KL R+IQ G+Y G YK+ E+ + L++QA A + Sbjct: 1167 SDKLTRLIQ----GDRNLPGVYIG----------YKNMKEMLPAHKEELNQQAAALIKQR 1212 Query: 430 YSGQD--IQSVSEICGLYVQGAEMDWEVCYQPGGYRRIRLPVYPFQKISCWPQADQ 483 QD I + L+VQGA +DW Y ++ LP+YPF++ CW +ADQ Sbjct: 1213 LRTQDERITWLHRAAELFVQGAVIDWRALYSGETVQKTPLPLYPFERSRCWAEADQ 1268 >emb|CAE11250.1| BmyA protein [Bacillus amyloliquefaciens] Length = 3982 Score = 383 bits (984), Expect = e-105, Method: Compositional matrix adjust. Identities = 211/476 (44%), Positives = 289/476 (60%), Gaps = 26/476 (5%) Query: 14 LTGSYTGILSSRISYFLDLKGPSIVLDSACSSGLLAIHDACQAIRNNECDMAIAGGVCLI 73 + G+ +L+SRI+YFL+LKGP++ +D+ACSS L A+H AC+++ + +C+MA+AGG+ Sbjct: 813 IVGNLPSVLASRIAYFLNLKGPAVTVDTACSSSLAAVHMACKSLISGDCEMALAGGIRTS 872 Query: 74 FFPMKNPAFGL-VESKLQLLKPFDKQADGTLWGEGIGSLLLKPLDKAVEDRDPIHAVIKG 132 P+ GL +ES K F K +DGT GEG ++LLKPL AV D D I+ VIKG Sbjct: 873 LLPI---CIGLDMESSDGYTKTFSKDSDGTGTGEGAAAVLLKPLQDAVRDGDHIYGVIKG 929 Query: 133 SAVNNDGRSNGLTAPNALAQEDLFTQAWINAEIAPETIGFYEAHGTGTVLGDPIEVQSLS 192 SA+N DG + G+TAPN AQ ++ AW +A IAPET+ F EAHGTGT LGDP+E L Sbjct: 930 SAMNQDGTTAGITAPNPAAQTEVIETAWKDAGIAPETLSFIEAHGTGTKLGDPVEFNGLC 989 Query: 193 NAFRKYTSKKQFCGIGSVKSNIGHLAAASGIASVMKTILSLKHQKLVSTLHFDDPNPFID 252 AF KYT+KKQFC IGSVKSNIGHL A+GI ++K++L L H+K HF++PNP I Sbjct: 990 KAFEKYTAKKQFCAIGSVKSNIGHLFEAAGIVGLIKSVLMLNHKKNPPLAHFNEPNPLIH 1049 Query: 253 FVGSPVYMVNKQQEWKRAQEDIPLRAGISSFGFSGTNLHLVLEEAPVSPKLAPASR--PY 310 F SP Y+ + E+ E PLR G+SSFGFSGTN H+VLEE + AP P Sbjct: 1050 FHSSPFYVNQEAAEFTSGDE--PLRGGVSSFGFSGTNAHVVLEEYISQSEYAPEDEHGP- 1106 Query: 311 HIFTVSAKEKTVLAEWVSRYLQHMQRAGDIELADLCYTAATGRGHYAYRLALIVRDIQEL 370 H+F +SA + L E +Y Q++ L +CYTA+TGR H + +A+IV QEL Sbjct: 1107 HLFVLSAHTEKSLYELAQQYRQYVSDDSQASLKSICYTASTGRAHLDHGIAMIVSGKQEL 1166 Query: 371 QEKLHRIIQEHPITGHTEDGIYYGEFKIVPESKKYKSTGEITESGLNLLHEQARAALGA- 429 +KL R+IQ G+Y G YK+ E+ + L++QA A + Sbjct: 1167 SDKLTRLIQ----GDRNLPGVYIG----------YKNMKEMLPAHKEELNQQAAALIKQR 1212 Query: 430 YSGQD--IQSVSEICGLYVQGAEMDWEVCYQPGGYRRIRLPVYPFQKISCWPQADQ 483 QD I ++ L+VQGA +DW Y ++ LP+YPF++ CW +ADQ Sbjct: 1213 LRTQDERITWLNRAAELFVQGAVIDWRALYSGETVQKTPLPLYPFERSRCWAEADQ 1268 >pir||T44806 mycosubtilin synthetase chain mycA [imported] - Bacillus subtilis gb|AAF08795.1| MycA [Bacillus subtilis] Length = 3971 Score = 374 bits (960), Expect = e-102, Method: Compositional matrix adjust. Identities = 206/473 (43%), Positives = 281/473 (59%), Gaps = 24/473 (5%) Query: 14 LTGSYTGILSSRISYFLDLKGPSIVLDSACSSGLLAIHDACQAIRNNECDMAIAGGVCLI 73 + G+ +L+SRI+YFL+LKGP++ +D+ACSS L+A+H AC+A+ +C+MA+AGG+ Sbjct: 814 IVGNLPSVLASRIAYFLNLKGPAVTVDTACSSSLVAVHMACKALLTGDCEMALAGGIRTS 873 Query: 74 FFPMKNPAFGL-VESKLQLLKPFDKQADGTLWGEGIGSLLLKPLDKAVEDRDPIHAVIKG 132 PM+ GL +ES L K F K +DGT GEG+ ++LLKPL A+ D D I+ VIKG Sbjct: 874 LLPMR---IGLDMESSDGLTKTFSKDSDGTGSGEGVAAVLLKPLQAAIRDGDHIYGVIKG 930 Query: 133 SAVNNDGRSNGLTAPNALAQEDLFTQAWINAEIAPETIGFYEAHGTGTVLGDPIEVQSLS 192 SA+N DG + G+TAP+ AQ ++ AW +A IAPET+ F EAHGTGT LGDP+E L Sbjct: 931 SAINQDGTTVGITAPSPAAQTEVIEMAWKDAGIAPETLSFIEAHGTGTKLGDPVEFNGLC 990 Query: 193 NAFRKYTSKKQFCGIGSVKSNIGHLAAASGIASVMKTILSLKHQKLVSTLHFDDPNPFID 252 AF K T KKQFC IGSVK+NIGHL A+GI ++K+ L L H+K+ HF+ PNP I Sbjct: 991 KAFEKVTEKKQFCAIGSVKANIGHLFEAAGIVGLIKSALMLNHKKIPPLAHFNKPNPLIP 1050 Query: 253 FVGSPVYMVNKQQEWKRAQEDIPLRAGISSFGFSGTNLHLVLEEAPVSPKLAPAS-RPYH 311 F SP Y+ Q+ ED PLR GISSFGFSGTN H+VLEE + AP H Sbjct: 1051 FHSSPFYV--NQEVMDFTPEDRPLRGGISSFGFSGTNAHVVLEEYTPESEYAPEDGNDPH 1108 Query: 312 IFTVSAKEKTVLAEWVSRYLQHMQRAGDIELADLCYTAATGRGHYAYRLALIVRDIQELQ 371 +F +SA + L E +Y Q++ L +CYTA+TGR H Y LA+IV QEL Sbjct: 1109 LFVLSAHTEASLYELTHQYRQYISDDSQSSLRSICYTASTGRAHLDYCLAMIVSSNQELI 1168 Query: 372 EKLHRIIQEHPITGHTEDGIYYGEFKIVPESKKYKSTGEITESGLNLLHEQARAALG--- 428 +KL +IQ GE + YK+ E+ + + L +Q + Sbjct: 1169 DKLTSLIQ--------------GERNLPQVHFGYKNIKEMQPAEKDNLSKQISDLMQHRP 1214 Query: 429 AYSGQDIQSVSEICGLYVQGAEMDWEVCYQPGGYRRIRLPVYPFQKISCWPQA 481 + I ++ I LYVQ A +DW Y ++ LP+YPF++ CW +A Sbjct: 1215 CTKDERITWLNRIAELYVQRAVIDWRAVYSNEVVQKTPLPLYPFERNRCWVEA 1267 >ref|ZP_00107678.1| COG1020: Non-ribosomal peptide synthetase modules and related proteins [Nostoc punctiforme] Length = 4682 Score = 359 bits (921), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 177/387 (45%), Positives = 261/387 (67%), Gaps = 14/387 (3%) Query: 6 LDQTDELALTGSYTGILSSRISYFLDLKGPSIVLDSACSSGLLAIHDACQAIRNNECDMA 65 L+ +D A G+ I+++R+S+ L+L+GPS+++D+ CSS L+A+H AC++++ EC A Sbjct: 1252 LNTSDYSAGIGNQNAIIANRVSFLLNLRGPSVLIDTMCSSSLVALHMACRSLQQGECTTA 1311 Query: 66 IAGGVCLIFFPMKNPAFGLVESKLQLLKP------FDKQADGTLWGEGIGSLLLKPLDKA 119 +AGGV L+ +P + + S++++ P FD QADG + GEG G+LLLKPL +A Sbjct: 1312 LAGGVNLLL----SPEYYVGMSRMKMHSPNGRCATFDSQADGIVLGEGAGALLLKPLSQA 1367 Query: 120 VEDRDPIHAVIKGSAVNNDGRSNGLTAPNALAQEDLFTQAWINAEIAPETIGFYEAHGTG 179 ++D D I+AVIKGSAVN+DGR+NG+TAPN+ + ++ QA A I+ +TI + EAHGTG Sbjct: 1368 LKDGDRIYAVIKGSAVNHDGRTNGITAPNSRSHAEVICQALDAAGISADTISYVEAHGTG 1427 Query: 180 TVLGDPIEVQSLSNAFRKYTSKKQFCGIGSVKSNIGHLAAASGIASVMKTILSLKHQKLV 239 T LGDPIEV+ L+ AFRKYT +KQFC IGSVK+NIGHL A+G+A ++K IL+++H+++ Sbjct: 1428 TSLGDPIEVEGLTKAFRKYTERKQFCKIGSVKTNIGHLECAAGMAQLLKVILAIQHRQIP 1487 Query: 240 STLHFDDPNPFIDFVGSPVYMVNKQQEWKRAQEDIPLRAGISSFGFSGTNLHLVLEEA-P 298 + LHF PNP I F +P + K W+ + RAGISSFG GTN H+V+EEA P Sbjct: 1488 ANLHFQQPNPLIPFAETPFQVNTKLCSWESSGLR---RAGISSFGIGGTNAHIVIEEAPP 1544 Query: 299 VSPKLAPASRPYHIFTVSAKEKTVLAEWVSRYLQHMQRAGDIELADLCYTAATGRGHYAY 358 + P + RP H+ T SAK + L + VSRY ++ D+ L D+C+TA TGR H+ + Sbjct: 1545 LEPVIPEIERPKHLLTFSAKTENALVQLVSRYETYLAANLDLPLGDICFTANTGRSHFQH 1604 Query: 359 RLALIVRDIQELQEKLHRIIQEHPITG 385 RL+ I +L ++L I + +TG Sbjct: 1605 RLSAIATSTSDLHQRLLNFISQQEVTG 1631 >ref|ZP_00074380.1| COG3321: Polyketide synthase modules and related proteins [Trichodesmium erythraeum IMS101] Length = 1909 Score = 346 bits (887), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 178/378 (47%), Positives = 251/378 (66%), Gaps = 10/378 (2%) Query: 14 LTGSYTGILSSRISYFLDLKGPSIVLDSACSSGLLAIHDACQAIRNNECDMAIAGGVCLI 73 + G+ L++R +Y L+L GP++ + +ACS+ L+A+H ACQ++ N ECDMA+AGGV I Sbjct: 156 MVGNDKDYLATRTAYKLNLTGPALNIQTACSTSLVAVHLACQSLLNGECDMALAGGVS-I 214 Query: 74 FFPMKNPAF----GLVESKLQLLKPFDKQADGTLWGEGIGSLLLKPLDKAVEDRDPIHAV 129 P +N + GL+ S + FD ++ GT++G G+G +LLKPL A+ D D IHAV Sbjct: 215 QIP-QNVGYLHQEGLIGSHDGHCRAFDARSSGTVFGNGVGVVLLKPLQDAIADGDCIHAV 273 Query: 130 IKGSAVNNDGRSN-GLTAPNALAQEDLFTQAWINAEIAPETIGFYEAHGTGTVLGDPIEV 188 IKGSA+NNDG G TAP+ Q + ++A A + PETI + EAHGTGT LGDPIE+ Sbjct: 274 IKGSAINNDGSLKLGYTAPSVDGQAAVISEAQAVASVTPETITYIEAHGTGTELGDPIEI 333 Query: 189 QSLSNAFRKYTSKKQFCGIGSVKSNIGHLAAASGIASVMKTILSLKHQKLVSTLHFDDPN 248 ++L+ AF ++T KKQFC IGS+K+N+GH+ A+GI +++KT+L+LKH + +LH++ PN Sbjct: 334 EALTKAFSEHTDKKQFCAIGSLKTNVGHMNTAAGIGALIKTVLTLKHNLIPPSLHYEKPN 393 Query: 249 PFIDFVGSPVYMVNKQQEWKRAQEDIPLRAGISSFGFSGTNLHLVLEEAPVSPKLA-PAS 307 P I+F SP Y+ + EWKR PLRAG+SSFG GTN H+VLEEAP K Sbjct: 394 PQINFSDSPFYVNSTLSEWKR--NGTPLRAGVSSFGIGGTNSHVVLEEAPSQVKEEDDLQ 451 Query: 308 RPYHIFTVSAKEKTVLAEWVSRYLQHMQRAGDIELADLCYTAATGRGHYAYRLALIVRDI 367 RP HI T+SAK T LA+ V Y +++ D++L D+CYTA TGR H+ +RLA++ Sbjct: 452 RPVHILTLSAKTPTALADLVDSYHHYLETNLDLDLGDVCYTANTGRVHFNHRLAVVAEKQ 511 Query: 368 QELQEKLHRIIQEHPITG 385 EL EKL + E + G Sbjct: 512 TELTEKLRQFKLEDKVEG 529 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.136 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 829,506,461 Number of extensions: 35549847 Number of successful extensions: 85773 Number of sequences better than 1.0e-05: 1852 Number of HSP's gapped: 80445 Number of HSP's successfully gapped: 2157 Length of query: 541 Length of database: 757,237,578 Length adjustment: 131 Effective length of query: 410 Effective length of database: 401,559,609 Effective search space: 164639439690 Effective search space used: 164639439690 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 128 (53.9 bits)