BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0003.p (2437 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00177151.1| hypothetical protein Cwat285401 [Crocosphaera... 508 e-142 ref|ZP_00125933.1| COG3319: Thioesterase domains of type I polyk... 491 e-136 ref|NP_522203.1| PROBABLE PEPTIDE SYNTHETASE PROTEIN [Ralstonia ... 491 e-136 pir||JX0340 gramicidin S synthase 2 - Bacillus brevis >gi|511490... 489 e-136 ref|ZP_00106169.1| COG1020: Non-ribosomal peptide synthetase mod... 488 e-136 >ref|ZP_00177151.1| hypothetical protein Cwat285401 [Crocosphaera watsonii WH 8501] Length = 6281 Score = 508 bits (1308), Expect = e-142, Method: Compositional matrix adjust. Identities = 326/1050 (31%), Positives = 551/1050 (52%), Gaps = 67/1050 (6%) Query: 1406 LQLEEPRVIIADIRLDQLDESVTGKLPLQLSPD---------LRRTG--NRFAQPRPVAA 1454 LQ E R +I+ QL E + KLP + P L G NR A P P+ Sbjct: 1852 LQQESNRNLIS-----QLPEFLLSKLPNYMVPSAFVTLEALPLTPNGKINRKALPDPLET 1906 Query: 1455 AADTIAIIGHSGAVISEMEQAVAQLWAKTFGLKKMDISKNFYELGGDSIMATQMANLLNT 1514 + I+ S + +E+ +A +W + G++ + ++ NF+ELGG S++AT++ + + Sbjct: 1907 QILSEEIVLPS----TPIEELLADIWTEILGIETVGVNNNFFELGGHSLIATRVVSQIRQ 1962 Query: 1515 QLHQKLSIAEIFEYPTVSGLAAYLEQSLPSRNEATAKAAGSEAPNAGYDLSKAQHRIWFL 1574 + +L + +FE PT++ LA +E+ + S E + + N LS AQ R+WFL Sbjct: 1963 VFNVELPLRSLFEKPTIAELAKEIEKVINSDVEVEFVSIERVSRNRELPLSFAQQRLWFL 2022 Query: 1575 QNYDPQTTAYHLPVVKQIREAIDLAVLQQGLDILTRRHSSLRTIIKNVNGIPKQFVVPDK 1634 +P + Y++ +++ +++ L+Q + + RRH +LRT + +G + P++ Sbjct: 2023 AELEPDSPFYNISGAVKLQGQLNVEALEQSFNEIVRRHENLRTNFQTRDGQAVAVISPER 2082 Query: 1635 SHVIHFTDYAQEPHXXXXXXXXXXXXNTTA--FELEQNLFRAELHRYE-ESDYLLYINMH 1691 + D + F++ ++L + E + ++ + MH Sbjct: 2083 PLNLSTVDISSLNGSTQEEKVRQEITKEAEKPFDISKDLLLRIKLLHLGEEENIVLVTMH 2142 Query: 1692 HIISDGWSMGVFFREWMELYDQIRSKRPIQLAPIALQPVDWVEQEKLWIGSGDYLNMERY 1751 HIISDGWSMGVF +E LY ++ PI L + +Q VD+ ++ W+ N Y Sbjct: 2143 HIISDGWSMGVFIKELGTLYTNFCNQEPISLQELPIQYVDFAAWQREWLQGEVLENQVSY 2202 Query: 1752 WMKELAQPLPVLELPTDYDRPHSIAYDGSYIKFTVSEEVTGQLRLLAKNRSSTLYMTVLA 1811 W+K+L +LELPT+ RP ++G+ F +S+E++ L L++ + STL+MT+LA Sbjct: 2203 WLKQLENTPKLLELPTNKPRPAIQTFNGATHSFELSKELSLALNKLSQQKGSTLFMTLLA 2262 Query: 1812 IYFLFLKKLSQEEDIIVGFPVSGREQQEWENIIGLFMNMVCIRVDFRELSSFGGVLEEVK 1871 + L + + +ED++VG P++ R + E E +IG F+N + +R + E SF +LE+V+ Sbjct: 2263 GFQTLLWRYTAQEDVVVGSPIANRNRGEIEGLIGFFVNTLVLRTNLAENPSFSELLEQVR 2322 Query: 1872 RKCLKAYANGRYPFNTLVEKLNPERDPSRTPVFSTIFQLYDNVP--------------QD 1917 L AY++ PF LVE+L PERD S +P+F +F L N P ++ Sbjct: 2323 EVTLGAYSHQDVPFELLVERLQPERDLSHSPLFQVMFVL-QNAPMSALELPGVTLTSLEN 2381 Query: 1918 NDRMSLYDLSCICKMDGGQIEVRLEYKTSLFTEETIQNYACYLTHLINQVIADPEGQLSR 1977 + + +DLS + EY T LF E+TI +L L++ ++A+P+ LS Sbjct: 2382 KHQTAKFDLSLYMTETESGLVGNFEYNTDLFEEKTITRMVGHLERLLSAIVANPQQPLSD 2441 Query: 1978 YELLDARHKAEIINQFHPLPVPMNPPDQVCRLFEAQVEQNPDQTAVVFEGERVSYRELDE 2037 LL + +++ +++ V + +LFEAQVE+ P+ AV FEG++++Y+EL++ Sbjct: 2442 LPLLSEPERHQLLWEWNQTKVEYPQNQCIHQLFEAQVEKTPEAVAVEFEGQKLTYQELNK 2501 Query: 2038 LSNQLAAFLVQLEQEPAEPVGVYLGRGIHMIAVLLGILKSGRPYVPLDPDFPPERIAYMI 2097 +NQ+A +L L +P VG+Y+ R + M+ LLGILK+G YVPL+P +P ERI Y++ Sbjct: 2502 KANQVAHYLRSLGVKPEVLVGIYIERSLEMVIGLLGILKAGGAYVPLEPTYPTERIQYLL 2561 Query: 2098 RHSGLRTVVSDGASIPKLLELASDVLKAVIDVAGDSTPAGTADHLSCYKYSDIRKQPVAR 2157 S + +++ I L E + ++ D+ P L + D PV+ Sbjct: 2562 EDSKVAILLTRNHLITTLPEYQGRI------ISLDTDP-----ELMTIERKD---NPVSG 2607 Query: 2158 IPSKAASELMYIIYTSGSTGTPKGVMVSQPNVINYLLWSRQQFQLGPQHHMMLVTSISFD 2217 + + L+YIIYTSGSTG PKG M + V+N LLW + +QL + ++ T SFD Sbjct: 2608 L---SRDNLIYIIYTSGSTGKPKGTMNTHQGVVNRLLWMEETYQLTSRDKVLQKTPFSFD 2664 Query: 2218 ISVFEIFGCLSSGATLHVVSSDRLRDPALLLAYMNQHKINFWHSVPVLMNQFLFGLSSQD 2277 +S +E + L +GA L V ++ +DP+ L+ + + +I H VP ++ F L D Sbjct: 2665 VSGWEFWWPLMTGACLVVAQTEGHKDPSYLIKLIKEKQITILHFVPSMLQIF---LEEAD 2721 Query: 2278 EKEIACLQHFDTVAIGGEAWSPKLAGDIRRSFPRAKLYNLYGPTEATIWATYYEAASDLT 2337 E+ + L+ V GEA + L S +A+L+NLYGPTEA I T+++ D + Sbjct: 2722 EESCSSLRK---VFCSGEALTVALQEKF-LSILKAELHNLYGPTEAAIDVTFWQCQVD-S 2776 Query: 2338 GKTVVPLGQPISNNRIFILDKDGNLCGPGIPGEICISGAGVTPGYFRDEETTAGVFRTHP 2397 + VP+G+P++N + +ILD + G+PGE+ + G + GY E TA F +P Sbjct: 2777 KLSSVPIGRPVANTQTYILDANLQPVPVGVPGELYLGGVQLARGYLNRPELTAERFIENP 2836 Query: 2398 FTDQI----VYHTGDIGKYGMGGQLEYIAR 2423 F++ +Y TGD+ +Y G +EY+ R Sbjct: 2837 FSEDFSSPRLYKTGDLVRYLADGNIEYLGR 2866 Score = 485 bits (1248), Expect = e-135, Method: Compositional matrix adjust. Identities = 308/1018 (30%), Positives = 527/1018 (51%), Gaps = 69/1018 (6%) Query: 1430 KLPLQLSPDLRRTGNRFAQPRPVAAAADTIAIIGHSGAVISEMEQAVAQLWAKTFGLKKM 1489 KLPL +P+ + +P+ ++ I + + +E+ +A + +K G++ + Sbjct: 4468 KLPL--TPNGKIDRKALPEPQETEILSEEIVLPS------TPIEELLAGILSKILGIETV 4519 Query: 1490 DISKNFYELGGDSIMATQMANLLNTQLHQKLSIAEIFEYPTVSGLAAYLEQSLPSRNEAT 1549 + NF+ELGG S++AT++ + + + +L + +FE PT++ LA +E+ + S E Sbjct: 4520 GVHNNFFELGGHSLIATRVVSQIRQVFNVELPLRSLFEKPTIAELAKEIEKVINSDVEVE 4579 Query: 1550 AKAAGSEAPNAGYDLSKAQHRIWFLQNYDPQTTAYHLPVVKQIREAIDLAVLQQGLDILT 1609 + + N LS AQ R+WFL +P + Y++ +++ +++ L+Q + + Sbjct: 4580 FVSIERVSRNRELPLSFAQQRLWFLAELEPDSPFYNISGAVKLQGQLNVEALEQSFNEIV 4639 Query: 1610 RRHSSLRTIIKNVNGIPKQFVVPDKSHVIHFTDYAQEPHXXXXXXXXXXXXNTTA--FEL 1667 RRH +LRT + +G + P++ + D + F++ Sbjct: 4640 RRHENLRTNFQTRDGQAVAVISPERPLNLSTVDISSLNGSTQEEKVRQEITKEAEKPFDI 4699 Query: 1668 EQNLFRAELHRYE-ESDYLLYINMHHIISDGWSMGVFFREWMELYDQIRSKRPIQLAPIA 1726 ++L + E + ++ + MHHIISDGWSMGVF +E LY ++ PI L + Sbjct: 4700 SKDLLLRIKLLHLGEEENIVLVTMHHIISDGWSMGVFIKELGTLYTNFCNQEPISLQELP 4759 Query: 1727 LQPVDWVEQEKLWIGSGDYLNMERYWMKELAQPLPVLELPTDYDRPHSIAYDGSYIKFTV 1786 +Q VD+ ++ W+ N YW+K+L +LELPT+ RP ++G+ F + Sbjct: 4760 IQYVDFAAWQREWLQGEVLENQVSYWLKQLENTPKLLELPTNKPRPAIQTFNGATHSFEL 4819 Query: 1787 SEEVTGQLRLLAKNRSSTLYMTVLAIYFLFLKKLSQEEDIIVGFPVSGREQQEWENIIGL 1846 S+E++ L L++ + STL+MT+LA + L + + +ED++VG P++ R + E E +IG Sbjct: 4820 SKELSLALNKLSQQKGSTLFMTLLAGFQTLLWRYTAQEDVVVGSPIANRNRGEIEGLIGF 4879 Query: 1847 FMNMVCIRVDFRELSSFGGVLEEVKRKCLKAYANGRYPFNTLVEKLNPERDPSRTPVFST 1906 F+N + +R + E SF +LE+V+ L AY++ PF LVE+L PERD S +P+F Sbjct: 4880 FVNTLVLRTNLAENPSFSELLEQVREVTLGAYSHQDVPFELLVERLQPERDLSHSPLFQV 4939 Query: 1907 IFQLYDNVP--------------QDNDRMSLYDLSCICKMDGGQIEVRLEYKTSLFTEET 1952 +F L N P ++ + + +DLS + EY T LF EET Sbjct: 4940 MFVL-QNAPMSALELPGVTLTSLENKHQTAKFDLSLYMTETESGLVGSFEYNTDLFEEET 4998 Query: 1953 IQNYACYLTHLINQVIADPEGQLSRYELLDARHKAEIINQFHPLPVPMNPPDQVC--RLF 2010 I +L L++ ++A+PE +LS LL + +++++++ V + +C +LF Sbjct: 4999 ITRMVGHLERLLSAIVANPEQRLSDLPLLSEPEQHQLLSEWNETKVEYS---SLCVHQLF 5055 Query: 2011 EAQVEQNPDQTAVVFEGERVSYRELDELSNQLAAFLVQLEQEPAEPVGVYLGRGIHMIAV 2070 E QVE+ P AV FE ++++Y EL+ +NQLA +L L +P VG+ + R + M+ Sbjct: 5056 EVQVEKTPLAVAVEFEDQKLTYHELNRKANQLAHYLRSLGVKPEVLVGICVERSLEMVIG 5115 Query: 2071 LLGILKSGRPYVPLDPDFPPERIAYMIRHSGLRTVVSDGASIPKLLELASDVLKAVIDVA 2130 LL ILK+G Y+PLDP++P ERI +++ + +P LL AS + Sbjct: 5116 LLAILKAGGAYLPLDPNYPQERIQFILEET----------QVPVLLTQASLM-------- 5157 Query: 2131 GDSTPAGTADHLSCYKYS-DIRKQPVARIPSKAASE-LMYIIYTSGSTGTPKGVMVSQPN 2188 D+ P TA + K S DI +Q + S ++ L Y IYTSGSTG PKGV + + Sbjct: 5158 -DTMPENTAQLVCIEKNSPDIEQQSQDNLISNLTTDNLAYTIYTSGSTGQPKGVQIPHSS 5216 Query: 2189 VINYLLWSRQQFQLGPQHHMMLVTSISFDISVFEIFGCLSSGATLHVVSSDRLRDPALLL 2248 + N+L +++ L + ++ VT+ SFDI+ E+F L GA L V S + + D LL Sbjct: 5217 LSNFLFSMKEEPGLSSKDTLLAVTTYSFDIAALELFLPLIVGARLIVASQEIVADGTQLL 5276 Query: 2249 AYMNQHKINFWHSVPVLMNQFL-FGLSSQDEKEIACLQHFDTVAIGGEAWSPKLAGDIRR 2307 A + K + P + G ++ ++ C GGE +LA ++ Sbjct: 5277 AKLTDSKTTVMQATPATWKLLIAAGWEGNEQLKVLC---------GGETLPSQLASELLE 5327 Query: 2308 SFPRAKLYNLYGPTEATIWATYYEAASDLTGKTVVPLGQPISNNRIFILDKDGNLCGPGI 2367 L+N+YGPTE TIW+ E +D ++ +G I+N +++ILD+ L G+ Sbjct: 5328 RC--ESLWNMYGPTETTIWSAVSEIKTD---SQLISIGNGIANTQLYILDQSSQLVPVGV 5382 Query: 2368 PGEICISGAGVTPGYFRDEETTAGVFRTHPFTDQ--IVYHTGDIGKYGMGGQLEYIAR 2423 GE+CI G G+ GYF+ E F +PF+++ +Y TGD+ +Y G++EY+ R Sbjct: 5383 VGELCIGGEGLARGYFQRRELNKEKFIYNPFSEEESRIYRTGDLARYLPNGEIEYLGR 5440 Score = 442 bits (1137), Expect = e-122, Method: Compositional matrix adjust. Identities = 291/958 (30%), Positives = 478/958 (49%), Gaps = 58/958 (6%) Query: 1487 KKMDISKNFYELGGDSIMATQMANLLNTQLHQKLSIAEIFEYPTVSGLAAYLEQSLPSRN 1546 + +D++ LG DSI + N + + + I + F + L + L + Sbjct: 463 QDIDLNTPLTNLGLDSIKVFEFKNKIEEDMGVTIPIEDFFAELNIKSLCNQILAQLDTPV 522 Query: 1547 EATAKAAGSEAPNAGYDLSKAQHRIWFLQNYDPQTTAYHLPVVKQIREAIDLAVLQQGLD 1606 EA+ + Y LS AQ RIWFL +P Y++ +I+ ++L VL+Q + Sbjct: 523 EASRAIIPTHRDGNFYQLSFAQKRIWFLAELEPDNPFYNISGTVRIQGHLNLEVLEQSFN 582 Query: 1607 ILTRRHSSLRTIIKNVNGIPKQFVVPDKSHVIHFTDYAQEPHXXXXXXXXXXXXNTTAFE 1666 + RRH +LRT + +G + ++ + D + TA E Sbjct: 583 EIIRRHETLRTNFQTRDGKAVAVIASERPIKLSIVDVS----SLSGSTQEEKVKQETAEE 638 Query: 1667 LEQN-------LFRAELHRYEESDYLLYINMHHIISDGWSMGVFFREWMELYDQIRSKRP 1719 E+ L R +L R E+ + L+ + +HHIISDGWS+GV +E LY ++ P Sbjct: 639 AEKPFDISNDPLLRVKLLRLEQEENLILVTLHHIISDGWSIGVLLQELTTLYTNFYNQEP 698 Query: 1720 IQLAPIALQPVDWVEQEKLWIGSGDYLNMERYWMKELAQPLPVLELPTDYDRPHSIAYDG 1779 + L + +Q VD+ ++ W+ N YW+K+L VLELP D R +Y G Sbjct: 699 LALQELPIQYVDFAAWQRQWLQGEVLENQMSYWLKQLENAPEVLELPADNPRQAIQSYRG 758 Query: 1780 SYIKFTVSEEVTGQLRLLAKNRSSTLYMTVLAIYFLFLKKLSQEEDIIVGFPVSGREQQE 1839 F +S+E++ L L++ + +TL+MT+LA + L + + +EDI+VG P++ R + E Sbjct: 759 KIYSFNLSKELSTSLNELSEQQGTTLFMTLLAGFQTLLWRYTAQEDIVVGSPIANRNRAE 818 Query: 1840 WENIIGLFMNMVCIRVDFRELSSFGGVLEEVKRKCLKAYANGRYPFNTLVEKLNPERDPS 1899 E +IG F+N + +R + SF +L++V+ L AYA+ PF+ LVE+L PER S Sbjct: 819 VEGLIGFFVNSLVLRTNLAGNPSFEELLKQVREVALGAYAHQDVPFDLLVERLQPERQLS 878 Query: 1900 RTPVFSTIFQLYDNVPQDND-----RMSLYDLSCICKMD--------GGQIEVRLEYKTS 1946 P+F +F L + D D L + S I + D I + EY T Sbjct: 879 HNPLFQVVFALLNTPMSDLDLPDATLTVLRNDSGIARCDLILYMTETESGIAGQFEYNTD 938 Query: 1947 LFTEETIQNYACYLTHLINQVIADPEGQLSRYELLDARHKAEIINQFHPLPVPMNPPDQV 2006 LF E+TI A ++ L++ ++ +P+ ++S LL A + +++ +++ + + + Sbjct: 939 LFEEKTISRMAGHIQTLLSAIVENPQQKVSEIPLLRATERHQLLVEWNETELEYSQNKCI 998 Query: 2007 CRLFEAQVEQNPDQTAVVFEGERVSYRELDELSNQLAAFLVQLEQEPAEPVGVYLGRGIH 2066 +LFE QV+ P+ AVVFE ++++Y EL++ +NQLA +L++L +P VG+ + R + Sbjct: 999 HQLFEEQVKTKPNGIAVVFEEQQLTYEELNKKANQLAHYLIKLGVKPDSLVGICVERSLE 1058 Query: 2067 MIAVLLGILKSGRPYVPLDPDFPPERIAYMIRHSGLRTVVSDGASIPKLLELASDVLKAV 2126 MI +LGILK+G Y+P+DPD+P ERI YM+ S + +++ + KL E S + Sbjct: 1059 MIIGVLGILKAGGAYLPIDPDYPQERIEYMLTDSEVNILLTQERLVEKLPENNSQ----I 1114 Query: 2127 IDVAGDSTPAGTADHLSCYKYSDIRKQPVARIPSKAASELMYIIYTSGSTGTPKGVMVSQ 2186 I + D + T ++ + + A L Y+IYTSGSTG PKGVM+ Sbjct: 1115 ISLDTDWSQIATKSDINLNQEIN-------------AENLAYVIYTSGSTGKPKGVMIEH 1161 Query: 2187 PNVINYLLWSRQQFQLGPQHHMMLVTSISFDISVFEIFGCLSSGATLHVVSSDRLRDPAL 2246 V N R++F++ + S SFD +EI L SGA L + D+ Sbjct: 1162 QGVCNLAQVQRERFKVNSSSRIFQFASFSFDACAWEIVMALLSGARLVITDKDKKLPGEN 1221 Query: 2247 LLAYMNQHKINFWHSVPVLMNQFLFGLSSQDEKEIACLQHFDTVAIGGEAWSPKLAGDIR 2306 L +N++ I P L +S ++ L T+ + GEA LA + Sbjct: 1222 LEKTLNEYGITHITLPP----SALTVMSPEN------LTQVKTIILAGEACPGTLAALWQ 1271 Query: 2307 RSFPRAKLYNLYGPTEATIWATYYEAASDLTGKTVVPLGQPISNNRIFILDKDGNLCGPG 2366 L+N YGPTE T+ AT E DL +P+G+PI+N +++ILDK+ G Sbjct: 1272 EG---RDLFNGYGPTEDTVCATIGEYQQDLEK---LPIGRPIANQQVYILDKNLEPVPIG 1325 Query: 2367 IPGEICISGAGVTPGYFRDEETTAGVFRTHPFTD-QIVYHTGDIGKYGMGGQLEYIAR 2423 + GE+ I G G+ GY E TA F ++P+ + +Y TGD+ +Y G +E++ R Sbjct: 1326 VSGELHIGGDGLARGYLNRPELTAEKFISNPWNSAEKLYKTGDLARYLADGNIEFVGR 1383 Score = 311 bits (798), Expect = 9e-83, Method: Compositional matrix adjust. Identities = 249/902 (27%), Positives = 432/902 (47%), Gaps = 96/902 (10%) Query: 1562 YDLSKAQHRIWFLQNYDPQTTAYHLPVVKQIREAIDLAVLQQGLDILTRRHSSLRTII-- 1619 Y LS Q + F +P++ Y + + I+L + + RHS LRT Sbjct: 3540 YPLSPMQEGMLFHTISEPESGVYFQQIALGLTGNIELLAFESAWQKVVDRHSVLRTFFVA 3599 Query: 1620 ----KNVNGIPKQFVVPDKSHVIHFTDYAQEPHXXXXXXXXXXXXNTTAFELEQN-LFRA 1674 K + + KQ +P ++ + + +Q+ F+L Q L + Sbjct: 3600 EDVEKPLQIVLKQVKLPWEN--MDWRGLSQQKQQEQLDELLSSQ-RLEGFQLNQAPLMKC 3656 Query: 1675 ELHRYEESDYLLYINMHHIISDGWSMGVFFREWMELYD-QIRSK-------RPIQLAPIA 1726 L E++Y ++ HHI+ DGW + + F+E + +Y+ +I+ K RP + Sbjct: 3657 ILIELSENNYKFVLSSHHILMDGWCLPIIFKEVLSIYEAEIQGKNFNLPRPRPYE----- 3711 Query: 1727 LQPVDWVEQEKLWIGSGDYLNMERYWMKEL---AQPLPVLELPTDYDRPHSIAYDGSYIK 1783 D+++ W+ + ++W + L P P++ + Y + + + I+ Sbjct: 3712 ----DYID----WLKLQNKETASQFWQETLQGFTAPTPLVVEKSQYQTQLNKS-NYQEIE 3762 Query: 1784 FTVSEEVTGQLRLLAKNRSSTLYMTVLAIYFLFLKKLSQEEDIIVGFPVSGREQQ--EWE 1841 +S +++ +L+ L++ TL + ++ L L S EEDI+ G VSGR E E Sbjct: 3763 LRLSPQLSRELQALSQKYHLTLSTIMQGVWGLLLSGYSGEEDIVFGVTVSGRPPSLPEVE 3822 Query: 1842 NIIGLFMNMVCIRVDFRELSSFGGVLEEVKRKCLKAYANGRYPFNTLVEKLNPERDPSRT 1901 +GLF+N + +R+ LEE+++ +A Y + LV+ P Sbjct: 3823 KRVGLFINTLPLRIQIPPQQQLIPWLEEIQQLMSQAQ---DYAYTPLVDIKAVSEVPGGM 3879 Query: 1902 PVFSTIFQLYDNVP--QDNDRMSLYDLSCICKMD------------GGQIEVRLEYKTSL 1947 P+F TI +++N P + + S ++S I + G Q+ +R+ Y T Sbjct: 3880 PLFETIM-VFENYPIGRSLTKDSALEISKIQSFEQTNYPLTVMAVPGEQLLIRVSYDTVR 3938 Query: 1948 FTEETIQNYACYLTHLINQVIADPEGQLSRYELLDARHKAEIINQFHPLPVPMNPPDQVC 2007 F ETI+ + +L + + ++ +P+ ++ LL + +++ +++ V + +C Sbjct: 3939 FESETIERMSEHLETMFSAIVKNPQQRVREIPLLTETERHQLLWEWNDTKVEYS---LLC 3995 Query: 2008 --RLFEAQVEQNPDQTAVVFEGERVSYRELDELSNQLAAFLVQLEQEPAEPVGVYLGRGI 2065 +LFEAQVE+ PD AV FE ++++Y++L+ +NQLA +L L +P VG+ + R + Sbjct: 3996 VDQLFEAQVEKTPDAVAVEFEDQKLTYQQLNTKANQLAHYLRCLGVKPEVLVGICVERSL 4055 Query: 2066 HMIAVLLGILKSGRPYVPLDPDFPPERIAYMIRHSGLRTVVSDGASIPKLLELASDVLKA 2125 M+ LL ILK+G Y+PLDP++P ERI +++ + +P LL AS + Sbjct: 4056 EMVIGLLAILKAGGAYLPLDPNYPQERIQFILEET----------QVPVLLTQASLL--- 4102 Query: 2126 VIDVAGDSTPAGTADHLSCYKYS-DIRKQPVARIPSKAASE-LMYIIYTSGSTGTPKGVM 2183 D+ P A L K S DI +Q I S+ ++ L Y IYTSGSTG PKGV Sbjct: 4103 ------DAMPKHRAQVLCIDKDSPDIEQQSQENITSEVTTDNLAYTIYTSGSTGKPKGVQ 4156 Query: 2184 VSQPNVINYLLWSRQQFQLGPQHHMMLVTSISFDISVFEIFGCLSSGATLHVVSSDRLRD 2243 + + N+L +++ L + ++ VT+ SFDI+ E+F L GA L V S + + D Sbjct: 4157 IPHSALSNFLFSMKEEPGLSSKDTLLAVTTYSFDIAALELFLPLVVGARLIVASQEIVAD 4216 Query: 2244 PALLLAYMNQHKINFWHSVPVLMNQFLFGLSSQDEKEIACLQHFDTVAIGGEAWSPKLAG 2303 LLA + K + P + L Q +++ L GGEA +LA Sbjct: 4217 GTQLLATLTDSKTTVMQATPATW-KLLIAADWQGNEQLKVL-------CGGEALPSQLAS 4268 Query: 2304 DIRRSFPRAKLYNLYGPTEATIWATYYEAASDLTGKTVVPLGQPISNNRIFILDKDGNLC 2363 ++ L+N+YGPTE TIW+ E +D ++ +G I+N +++ILD+ L Sbjct: 4269 ELLERC--ESLWNMYGPTETTIWSAVSEIKTD---SQLISIGNGIANTQLYILDQSSQLV 4323 Query: 2364 GPGIPGEICISGAGVTPGYFRDEETTAGVFRTHPFTDQ--IVYHTGDIGKYGMGGQLEYI 2421 G+ GE+CI G G+ GYF E F +PF+++ +Y TGD+ +Y G++EY+ Sbjct: 4324 PVGVVGELCIGGMGLARGYFERPELNKEKFIYNPFSEEESRIYRTGDLARYLPNGEIEYL 4383 Query: 2422 AR 2423 R Sbjct: 4384 GR 4385 Score = 237 bits (605), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 160/571 (28%), Positives = 286/571 (50%), Gaps = 30/571 (5%) Query: 1430 KLPLQLSPDLRRTGNRFAQPRPVAAAADTIAIIGHSGAVISEMEQAVAQLWAKTFGLKKM 1489 KLPL +P+ + +R A P P + I+ S + +E+ +A +W + G++ + Sbjct: 5523 KLPL--TPNGKI--DRKALPVPEKTPISSNEIVLPS----TPIEELLAGIWTEILGIETV 5574 Query: 1490 DISKNFYELGGDSIMATQMANLLNTQLHQKLSIAEIFEYPTVSGLAAYLEQSLPSRNEAT 1549 I +F+ELGG S++AT++ + + + + + +FE PT++ LA +E+ + S Sbjct: 5575 GIHNDFFELGGHSLIATRIMSQIRQVFNVDIPLRNLFEKPTIAELAKEIEKVINSDVGVE 5634 Query: 1550 AKAAGSEAPNAGYDLSKAQHRIWFLQNYDPQTTAYHLPVVKQIREAIDLAVLQQGLDILT 1609 + + LS AQ R+WFL +P + Y++ ++ +I++AVL+Q + + Sbjct: 5635 VVSIERVSREQELPLSFAQQRLWFLAQIEPDSPFYNMSSTIEVEGSINVAVLEQSFNEII 5694 Query: 1610 RRHSSLRTIIKNVNGIPKQFVVPDKSHVI-----HFTDYAQEPHXXXXXXXXXXXXNTTA 1664 RRH SLRT P Q + P++S I H D ++ T Sbjct: 5695 RRHESLRTTFAMGENGPIQIIAPEQSIKITTIDLHNLDVNEQTEQVQKLALEEAQ---TP 5751 Query: 1665 FELEQNLF-RAELHRYEESDYLLYINMHHIISDGWSMGVFFREWMELYDQIRSKRPIQLA 1723 F L L R L + E +L +N+HHIISD WSMGV +E Y+ + + +P+QL Sbjct: 5752 FNLADGLLIRISLLQLGERKNVLLLNIHHIISDAWSMGVLVKELATFYENLVNDKPVQLP 5811 Query: 1724 PIALQPVDWVEQEKLWIGSGDYLNMERYWMKELAQPLPVLELPTDYDRPHSIAYDGSYIK 1783 + +Q D+ ++ + + YW ++L+ +PTD RP + G+ + Sbjct: 5812 ELPIQYADFAVWQRQPLQAEKLDKQLAYWRQQLSGVPDSFNIPTDKPRPELQTFRGAVSE 5871 Query: 1784 FTVSEEVTGQLRLLAKNRSSTLYMTVLAIYFLFLKKLSQEEDIIVGFPVSGREQQEWENI 1843 F++S E++ ++ L++ TL+MT+LA L L K +++D++VG V+ R +E E++ Sbjct: 5872 FSLSTELSEKVTHLSRQEGVTLFMTLLATLQLLLYKYKKQKDVLVGTDVANRNYKEVESL 5931 Query: 1844 IGLFMNMVCIRVDFRELSSFGGVLEEVKRKCLKAYANGRYPFNTLVEKLNPERDPSRTPV 1903 IG F+N++ +R +F +F +LE+V+ L AYAN +PF LVE + PER+ SRTP+ Sbjct: 5932 IGFFINILVLRANFSGNPTFRELLEQVREVTLGAYANQDFPFTKLVETVRPERNLSRTPL 5991 Query: 1904 FSTIFQLYDN-VPQ------------DNDRMSLYDLSCICKMDGGQIEVRLEYKTSLFTE 1950 F +F L + +PQ + S +D++ ++ +Y + LF Sbjct: 5992 FQVLFVLNNTPIPQLEVSGLKFTPLMVDTETSKFDMALFVSETETGLKGMWQYNSDLFDL 6051 Query: 1951 ETIQNYACYLTHLINQVIADPEGQLSRYELL 1981 T+ + L+N ++ P + E+L Sbjct: 6052 STMTRLSAQFETLLNNIVNQPNTSIESLEIL 6082 >ref|ZP_00125933.1| COG3319: Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Pseudomonas syringae pv. syringae B728a] Length = 6656 Score = 491 bits (1263), Expect = e-136, Method: Compositional matrix adjust. Identities = 338/1051 (32%), Positives = 519/1051 (49%), Gaps = 84/1051 (7%) Query: 1407 QLEEPRVIIADIRLDQLDESVTGKLPLQLSPDLRRTGNRFAQPRPVAAAADTIAIIGHSG 1466 QL + +A + LD L + GKL +R A P P AD + G+ Sbjct: 2776 QLPAYMIPVAYVLLDALPLTPNGKL------------DRKALPAP---DADALIRRGYE- 2819 Query: 1467 AVISEMEQAVAQLWAKTFGLKKMDISKNFYELGGDSIMATQMANLLNTQLHQKLSIAEIF 1526 A E E +AQ+W+ L+++ F+ELGG S++A ++ + + QL +LS+A +F Sbjct: 2820 APQGETETLLAQIWSDLLQLERVSRHDQFFELGGHSLLAMRLISQIRQQLGVELSLAALF 2879 Query: 1527 EYPTVSGLAAYLEQSLPSRNEATAKAAGSEAPNAGYDLSKAQHRIWFLQNYDPQTTAYHL 1586 +P +S LA + Q+ S A +A + LS Q R+WFL + + AYH+ Sbjct: 2880 AHPELSALALAIAQAGRSILPDIVPVARDQA----WPLSFGQQRLWFLAKMEGASAAYHM 2935 Query: 1587 PVVKQIREAIDLAVLQQGLDILTRRHSSLRT-IIKNVNGIPKQFVVP-DKSHVIHFTDYA 1644 PV +R +D A +Q+ L+ + RH LRT I+ + P Q + P D + D Sbjct: 2936 PVGLGLRGELDRAAMQRALERIVARHEGLRTTFIQGDDEQPLQRISPADAGFNLQLHDLQ 2995 Query: 1645 QEPHXXXXXXXXXXXXNTTAFELEQN-LFRAELHRYEESDYLLYINMHHIISDGWSMGVF 1703 + F+LEQ L R L R E ++L + MHHI+SDGWS+GV Sbjct: 2996 GLVDAKEKLQALASEESLQGFDLEQGPLIRGRLIRMAEDHHVLLLTMHHIVSDGWSIGVL 3055 Query: 1704 FREWMELYDQIRSKRPIQLAPIALQPVDWVEQEKLWIGSGDYLNMER-YWMKELAQPLPV 1762 RE LY + LAP+ LQ +D+ ++ W+ SGD L + YW + LA + Sbjct: 3056 TRELAALYAAFSQGQDDPLAPLTLQYLDYAVWQRRWL-SGDLLQQQSDYWQQTLADAPAL 3114 Query: 1763 LELPTDYDRPHSIAYDGSYIKFTVSEEVTGQLRLLAKNRSSTLYMTVLAIYFLFLKKLSQ 1822 L LPTD RP Y G+ + E++T L+ L++ STL+MT++A + L +LS Sbjct: 3115 LMLPTDRVRPAQQDYAGAVLPIVFDEDLTRGLKALSQRHGSTLFMTIMAAWAALLGRLSG 3174 Query: 1823 EEDIIVGFPVSGREQQEWENIIGLFMNMVCIRVDFRELSSFGGVLEEVKRKCLKAYANGR 1882 ++D+++G PV+ R + E E ++GLF+N + IRVD + + +L +VK L A + Sbjct: 3175 QDDVVIGTPVANRTRSEAEGLVGLFVNTLAIRVDLSDKPTAETLLAQVKTNTLGAQDHQD 3234 Query: 1883 YPFNTLVEKLNPERDPSRTPVFSTIFQLYDNVPQD-------------NDRMSLYDLSCI 1929 PF +VE + P R S +PVF + D D +S +DLS Sbjct: 3235 LPFEQVVEVIKPVRSLSHSPVFQAMLSWQDMSGGDLVLGDLQLESLSAGHTLSKFDLSLD 3294 Query: 1930 CKMDGGQIEVRLEYKTSLFTEETIQNYACYLTHLINQVIADPEGQLSRYELLDARHKAEI 1989 GQ+ LEY T+LF E TI Y YL L++ ++AD L LLDA + + Sbjct: 3295 IGEAQGQLLGSLEYATALFDESTIARYLGYLKRLLHAMVADDRQALEHVPLLDAVERKHL 3354 Query: 1990 INQFHPLPVPMNPPDQVCRLFEAQVEQNPDQTAVVFEGERVSYRELDELSNQLAAFLVQL 2049 + + VP + +LFE +V P+ AV F+ +R+SY +L+ +N+LA L+ L Sbjct: 3355 LIDLNATNVPYPQDATIHQLFEEKVRAQPEAIAVAFQAQRLSYADLNRQANRLAHHLISL 3414 Query: 2050 EQEPAEPVGVYLGRGIHMIAVLLGILKSGRPYVPLDPDFPPERIAYMIRHSGLRTVVSDG 2109 P + V + + RG+ MI LLG+LK+G YVPLDP +P ER+AYMI S +++ Sbjct: 3415 GIGPDDRVAICVERGVKMIVGLLGVLKAGAAYVPLDPAYPAERLAYMINDSQPAALLTQR 3474 Query: 2110 ASIPKLLELASDVLKAVIDVAGDSTPAGTADHLSCYKYSDIRKQPVARIPSKAASELMYI 2169 +L L S P D C +++ PV +P+ L Y+ Sbjct: 3475 GLQERLPAL--------------SMPLVLLDDEHCQGFTECDDNPV--VPTLGVRNLAYV 3518 Query: 2170 IYTSGSTGTPKGVMVSQPNVINYLLWSRQQFQLGPQHHMMLVTSISFDISVFEIFGCLSS 2229 IYTSGSTG PKGVM+ ++NY + + + F L ++ +++FD+SV EIF L + Sbjct: 3519 IYTSGSTGNPKGVMIEHRGLVNYSVDAARLFGLSQSDTVLQQNTLNFDLSVEEIFPALLA 3578 Query: 2230 GATL----HVVSSDRLRD----PALL-LAYMNQHK-INFWHSVPVLMNQFLFGLSSQDEK 2279 GATL + S+ + P +L L + H + WH+ P E+ Sbjct: 3579 GATLAPSREIFGSEGTENHGIYPTVLHLTAAHWHTLVAEWHNQP-----------QAAEQ 3627 Query: 2280 EIACLQHFDTVAIGGEAWSPKLAGDIRRSFPRAKLYNLYGPTEATIWAT----YYEAASD 2335 +A ++ + A KL ++R + R L N YGPTEAT+ T ++AA+ Sbjct: 3628 RLAEVRLINVTGDALSAQKLKLWDEVRPAHTR--LINTYGPTEATVSCTAAYVSHDAAAG 3685 Query: 2336 LTGKTVVPLGQPISNNRIFILDKDGNLCGPGIPGEICISGAGVTPGYFRDEETTAGVFRT 2395 G +G+P++N RI++LD+ G+ GEI I G GV GY EE A F Sbjct: 3686 SEGSGNATIGKPMANTRIYLLDEHQQPVPYGVAGEIFIGGDGVARGYLNLEEVNAERFLA 3745 Query: 2396 HPFT---DQIVYHTGDIGKYGMGGQLEYIAR 2423 PF+ D +Y TGD+ +Y G++EY+ R Sbjct: 3746 DPFSNSPDARMYKTGDLARYMADGRIEYLGR 3776 Score = 453 bits (1165), Expect = e-125, Method: Compositional matrix adjust. Identities = 318/1022 (31%), Positives = 510/1022 (49%), Gaps = 68/1022 (6%) Query: 1433 LQLSPDLRRTGNRFAQPRPVAAAADTIAIIGHSGAVISEMEQAVAQLWAKTFGLKKMDIS 1492 L L+P+ R +R A P P A D A H A E+A+AQ+W L+ + Sbjct: 3860 LPLTPN--RKLDRKALPAP---ADDAFASREHV-APQGTSEKALAQIWQNLLNLEAVGRH 3913 Query: 1493 KNFYELGGDSIMATQMANLLNTQLHQKLSIAEIFEYPTVSGLAAYLEQSLPSRNEATAKA 1552 +F+ELGG S++A ++ + + ++ +LS+A+IF P ++ LA + + S + Sbjct: 3914 DHFFELGGHSLLAMRLISQVRQRMGVELSLADIFAQPELAALAQVVAHAAGSSQQPIVPV 3973 Query: 1553 AGSEAPNAGYDLSKAQHRIWFLQNYDPQTTAYHLPVVKQIREAIDLAVLQQGLDILTRRH 1612 + ++ LS AQ R+WFL D + AYH+P ++R ++D L++ LD + RH Sbjct: 3974 SRDQS----LPLSFAQQRLWFLAQLDGGSAAYHIPAGLRLRGSLDQVALKRALDRIVARH 4029 Query: 1613 SSLRT-IIKNVNGIPKQFVVP-DKSHVIHFTDYAQEPHXXXXXXXXXXXXNTTAFELEQN 1670 +LRT ++ + P Q + P D + + F+L Sbjct: 4030 EALRTTFVQEQDQDPLQCIAPADIGFSLQLQVLNGQADAEQQLLAIAAEEAEEGFDLVNG 4089 Query: 1671 -LFRAELHRYEESDYLLYINMHHIISDGWSMGVFFREWMELYDQIRSKRPIQLAPIALQP 1729 L R L R + D++L + MHHI+SDGWS GV RE LY L + +Q Sbjct: 4090 PLVRGRLVRMADDDHVLLVTMHHIVSDGWSAGVLTRELGMLYAAFSEGAEDPLPALPVQY 4149 Query: 1730 VDWVEQEKLWIGSGDYLNMERYWMKE-LAQPLPVLELPTDYDRPHSIAYDGSYIKFTVSE 1788 D+ ++ W+ SGD L +R + ++ LA +L LPTD RP Y G + + Sbjct: 4150 ADYALWQRNWL-SGDVLQQQRQYWQQTLAGAPALLTLPTDRPRPAQQDYSGQLLGLVLDA 4208 Query: 1789 EVTGQLRLLAKNRSSTLYMTVLAIYFLFLKKLSQEEDIIVGFPVSGREQQEWENIIGLFM 1848 ++T L+ L++ S+L+MTV+A + L +L+ ++D+++G PV+ R + E E++IG F+ Sbjct: 4209 DLTRGLKALSQRHGSSLFMTVMAAWAALLGRLAGQDDVVIGTPVANRMRAEVEDLIGFFV 4268 Query: 1849 NMVCIRVDFRELSSFGGVLEEVKRKCLKAYANGRYPFNTLVEKLNPERDPSRTPVFSTIF 1908 N + +RVD S +L++VK++ L A AN PF +VE + P+R S +P+F + Sbjct: 4269 NTLAVRVDLSGTPSVQSLLQQVKQQTLAAQANQDLPFEQVVEVVRPQRSLSHSPIFQAML 4328 Query: 1909 QLYDNVPQD--NDRMSL-----------YDLSCICKMDGGQIEVRLEYKTSLFTEETIQN 1955 +N D MSL +DL+ G Q+ LEY T+LF E T+Q Sbjct: 4329 SWQNNETSDLALGDMSLQGVAVAGHTAKFDLTLDMTEVGDQLIGTLEYATALFDESTLQR 4388 Query: 1956 YACYLTHLINQVIADPEGQLSRYELLDARHKAEIINQFHPLPVPMNPPDQVCRLFEAQVE 2015 Y Y L+ ++AD L + LLDA + ++ + VP + +LFEA+V+ Sbjct: 4389 YMGYFQRLLEAMVADDRQLLEQVPLLDAVERQHLLVDLNATDVPYPHDCTIHQLFEAKVQ 4448 Query: 2016 QNPDQTAVVFEGERVSYRELDELSNQLAAFLVQLEQEPAEPVGVYLGRGIHMIAVLLGIL 2075 PD AV F+ +R+SY EL+ +N+LA L+ L P + V + + RG+ M+ LLG+L Sbjct: 4449 AQPDAIAVAFQAQRLSYAELNRQANRLAHHLIGLGIGPDDRVAICVERGVEMMIGLLGVL 4508 Query: 2076 KSGRPYVPLDPDFPPERIAYMIRHSGLRTVVSDGASIPKLLELASDVLKAVIDVAGDSTP 2135 K+G YVPLDP +P ER+AYMI S P L D+ K + + Sbjct: 4509 KAGAAYVPLDPAYPAERLAYMITDSQ-----------PAALLTQRDLQKRLPTLTLPLVL 4557 Query: 2136 AGTADHLSCYKYSDIRKQPVARIPSKAASELMYIIYTSGSTGTPKGVMVSQPNVINYLLW 2195 + + D PV + + L Y+IYTSGSTG PKGVM+ ++NY + Sbjct: 4558 LDDDQRNTFTERDD---NPV--VEALGVRNLAYVIYTSGSTGNPKGVMIEHRGLVNYSVD 4612 Query: 2196 SRQQFQLGPQHHMMLVTSISFDISVFEIFGCLSSGATL----HVVSSDRLRDPALLLAYM 2251 + + F L ++ +++FD+SV EIF L +GATL + S+ + + + Sbjct: 4613 AARLFALSQSDTVLQQNTLNFDLSVEEIFPALLAGATLAPSREIFGSEGTENHGIYPTVL 4672 Query: 2252 NQHKINFWHSVPVLMNQFLFGLSSQDEKEIACLQHFDTVAIGGEAWSP---KLAGDIRRS 2308 + + WH+ L+ ++ +Q + L + + G+A S KL ++R + Sbjct: 4673 HLTAAH-WHT---LVAEW----HNQPQAAAQRLAEVRLINVTGDALSAQKLKLWDEVRPA 4724 Query: 2309 FPRAKLYNLYGPTEATIWAT----YYEAASDLTGKTVVPLGQPISNNRIFILDKDGNLCG 2364 R L N YGPTEAT+ T ++AA+ G +G+P++N RI++LD Sbjct: 4725 HTR--LINTYGPTEATVSCTAAYVSHDAAAGSEGSGNATIGKPMANTRIYLLDAHQQPVP 4782 Query: 2365 PGIPGEICISGAGVTPGYFRDEETTAGVFRTHPFTDQ---IVYHTGDIGKYGMGGQLEYI 2421 G+ GEI I G GV GY EE A F PF++ +Y TGD+ +Y G++EY+ Sbjct: 4783 YGVAGEIFIGGDGVARGYLNLEEVNAERFLADPFSNSPEARMYKTGDLARYMADGRIEYL 4842 Query: 2422 AR 2423 R Sbjct: 4843 GR 4844 Score = 412 bits (1059), Expect = e-113, Method: Compositional matrix adjust. Identities = 306/1024 (29%), Positives = 472/1024 (46%), Gaps = 87/1024 (8%) Query: 1433 LQLSPDLRRTGNRFAQPRPVAAAADTIAIIGHSGAVISEMEQAVAQLWAKTFGLKKMDIS 1492 L L+P+ R +R A P P A A + + G + E A+AQ+W L+++ Sbjct: 4928 LPLTPN--RKLDRKALPAPQAEAFASREHVEPQG----DTEMALAQIWQNLLNLEQVGRH 4981 Query: 1493 KNFYELGGDSIMATQMANLLNTQLHQKLSIAEIFEYPTVSGLAAYLEQSLPSRNEATAKA 1552 F+ELGG S++A ++ + + L +L +A+IF P ++ +A L A A Sbjct: 4982 DQFFELGGHSLLAMRLISQVRQHLGVELGLADIFAQPELAAMARIL-----------ADA 5030 Query: 1553 AGSEAP-------NAGYDLSKAQHRIWFLQNYDPQTTAYHLPVVKQIREAIDLAVLQQGL 1605 GS P + LS AQ R+WFL + + AYH+P ++R +D L++ L Sbjct: 5031 KGSSQPPIVPVSRDQTLPLSFAQQRLWFLAQLEGGSAAYHIPAGLRLRGTLDNPALKRAL 5090 Query: 1606 DILTRRHSSLRTIIKNVNG--IPKQFVVPDKSHVIHFTDYAQEPHXXXXXXXXXXXXNTT 1663 D + RH LRT V+G + + D + + Sbjct: 5091 DRIVARHEVLRTTFVQVHGEDVAQHIASADIGFSLQLQVLTGQADAEEQLLAITAEEANE 5150 Query: 1664 AFELEQN-LFRAELHRYEESDYLLYINMHHIISDGWSMGVFFREWMELYDQIRSKRPIQL 1722 F+L L R L R E D++L + MHHI+SDGWS V RE LY + L Sbjct: 5151 GFDLLNGPLVRGRLVRMAEDDHVLLVTMHHIVSDGWSADVLTRELSALYAAFSAGAEDPL 5210 Query: 1723 APIALQPVDWVEQEKLWIGSGDYLNMERYWMKELAQPLP-VLELPTDYDRPHSIAYDGSY 1781 + +Q D+ ++ W+ SGD L +R + ++ P +L LPTD RP Y G+ Sbjct: 5211 PTLPVQYADYAVWQRNWL-SGDVLQQQRQYWQQTLGGAPALLTLPTDRPRPAQQDYSGNI 5269 Query: 1782 IKFTVSEEVTGQLRLLAKNRSSTLYMTVLAIYFLFLKKLSQEEDIIVGFPVSGREQQEWE 1841 + E+T L+ L++ STL+MTV+ + L +L+ ++D+++G PV+ R + E E Sbjct: 5270 RGLVLDAELTSGLKALSQRHGSTLFMTVMVAWASLLGRLAGQDDVVIGTPVANRLRAEVE 5329 Query: 1842 NIIGLFMNMVCIRVDFRELSSFGGVLEEVKRKCLKAYANGRYPFNTLVEKLNPERDPSRT 1901 ++IG F+N + IRVD S ++++VKR+ L A ++ PF +VE + P+R S + Sbjct: 5330 DLIGFFVNTLAIRVDLSGAPSVEALMQQVKRQTLAAQSHQDLPFEQVVEVVRPQRSMSHS 5389 Query: 1902 PVFSTIFQLYDNVPQD-------------NDRMSLYDLSCICKMDGGQIEVRLEYKTSLF 1948 P+F + +N D ND + +DL G Q+ LEY T+LF Sbjct: 5390 PIFQAMLSWQNNETSDLSLGAMNLQGVAVNDHTAKFDLVLDMTEVGDQLIGTLEYATALF 5449 Query: 1949 TEETIQNYACYLTHLINQVIADPEGQLSRYELLDARHKAEIINQFHPL--PVPMNPPDQV 2006 E T+ Y Y L+ ++A+ L L+DA + +++ + P P + Sbjct: 5450 DESTMDRYLGYFQRLLEAMVANEHRILEHVPLVDAVEREHLLSGLNATDRAYPQGP--LM 5507 Query: 2007 CRLFEAQVEQNPDQTAVVFEGERVSYRELDELSNQLAAFLVQLEQEPAEPVGVYLGRGIH 2066 RLFEA P A + ++Y ELD +N LA L Q + V + L R + Sbjct: 5508 HRLFEAHAASRPQAIAARQGEQTLTYAELDSRANALAQHLRQHGVKAGARVAILLDRSVE 5567 Query: 2067 MIAVLLGILKSGRPYVPLDPDFPPERIAYMIRHSGLRTVVSDGASIPKLLELASDVLKAV 2126 ++ +L LK G Y+ LD P ER+ +M+ S L+ L L Sbjct: 5568 LLTSMLATLKCGAAYLALDRLAPEERVRFMLEDS------------EALMLLTRSEL--- 5612 Query: 2127 IDVAGDSTPAGTADHLSCYKYSDIRKQPVARIPSKAASELMYIIYTSGSTGTPKGVMVSQ 2186 A ++TP D L S + PVA A IIYTSGSTG PKGV+V+ Sbjct: 5613 --TAPETTPRLDLDTLDL---SVAGQGPVALAAEVAGETPACIIYTSGSTGIPKGVIVTH 5667 Query: 2187 PNVINYLLWSRQQFQLGPQHHMMLVTSISFDISVFEIFGCLSSGATLHVVSSDRLRDPAL 2246 ++ + R + + ++ +FD S EI+G L +G +V L +PA Sbjct: 5668 NGIVRLV---RDNYDFRADDRVAFSSNPAFDASSPEIWGALLNGGQSIIVEPSVLLEPAA 5724 Query: 2247 LLAYMNQHKINFWHSVPVLMNQFLFGLSSQDEKEIACLQHFDTVAIGGEAWSPKLAGDIR 2306 A + +H + S L N + GL + L + GGE P +R Sbjct: 5725 FAALLKRHAVTVMFSSTALFNLYA-GLIPE------ALAGLRMLECGGERADPASFRRVR 5777 Query: 2307 RSFPRAKLYNLYGPTEATIWATYYEAASDLTGKTVVPLGQPISNNRIFILDKDGNLCGPG 2366 + +L+N YGPTEAT AT YE G +P+G+P +N RI++LD +CG Sbjct: 5778 EHSSQVRLFNGYGPTEATTCATRYEVFDVQPGTLSLPIGKPNANVRIYLLD----VCGEP 5833 Query: 2367 IP----GEICISGAGVTPGYFRDEETTAGVFRTHPFTDQI---VYHTGDIGKYGMGGQLE 2419 +P GEI I G GV GY E +A F PF+ Q +Y TGD+ ++ G LE Sbjct: 5834 VPMGSVGEIYIGGVGVALGYLNRPELSAERFSDDPFSQQAGARLYRTGDLARWLPDGNLE 5893 Query: 2420 YIAR 2423 Y+AR Sbjct: 5894 YLAR 5897 Score = 250 bits (638), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 220/783 (28%), Positives = 362/783 (46%), Gaps = 100/783 (12%) Query: 1677 HRYEESDYLLYINMHHIISDGWSMGVFFREWMELYDQIRSKRPIQLA--PIALQPVDWVE 1734 H E +L + HH++ D S+ L +I S Q A P ++ ++V Sbjct: 1989 HDAENDRWLGMLLFHHLVDDATSL-------RTLTSEIESYMLGQQASLPPSVPYRNYVA 2041 Query: 1735 QEKLWIGSGDYLNMERYWMKELAQP-LPVLELPTDYDRPHSIAYDGSYIKFT---VSEEV 1790 Q L + ++ R + ++ +P LP L + DG I+ V ++ Sbjct: 2042 QAMLGVSREEHEAFFRDMLGDIDEPTLPFGLL--------DVQGDGRGIEEVHQPVDMDL 2093 Query: 1791 TGQLRLLAKN---RSSTLYMTVLAIYFLFLKKLSQEEDIIVGFPVSGREQ--QEWENIIG 1845 + +LRL A+ S++LY A L +S +E+++ G + GR Q + +G Sbjct: 2094 SRRLRLQARQFGVSSASLYHLAWA---RVLGAVSGKEEVVFGTVLLGRLQGGAGSDRALG 2150 Query: 1846 LFMNMVCIRVDFRELSSFGGVLEEVKRKCLKAYANGRYPFNTLVEKLNPERDPSRTPVFS 1905 +F+N + +RV E GV +K + + +LV + TP+FS Sbjct: 2151 MFINTLPLRVTLGE----QGVRSGLKATHTRLSGLLAHEHASLVLAQRCSGVAASTPLFS 2206 Query: 1906 TIFQLYDNVPQDNDRMSLYDLSCICKMDGGQIEVRLEYKTSLFTEE-------TIQNYAC 1958 + Y +V ++ +L I + G E R Y +L + TIQ AC Sbjct: 2207 ALLN-YRHVAGQANQQTLDAWQGIESLRG---EERTNYPLTLSVNDEGTGFSLTIQASAC 2262 Query: 1959 --------YLTHLINQVIADPEGQ----LSRYELLDARHKAEIINQFHPLPVPMNPPDQV 2006 Y+ + V++ E L+ +L A + ++ + + + Sbjct: 2263 IDAQRICAYVQTTLENVVSALEQSGEVPLAGLSVLSAAEREHLVYGLNATALDYPQQQTI 2322 Query: 2007 CRLFEAQVEQNPDQTAVVFEGERVSYRELDELSNQLAAFLVQLEQEPAEPVGVYLGRGIH 2066 +FEAQVE+ P+ AVV +R+ YREL+E +N+LA L++ +P VG+ + RG+ Sbjct: 2323 HGMFEAQVERTPEGVAVVHGEQRLRYRELNEQANRLAHALIKQGVQPDSRVGICVERGVE 2382 Query: 2067 MIAVLLGILKSGRPYVPLDPDFPPERIAYMIRHSGLRTVVSDGASIPKLLELASDVLKAV 2126 M+ LL +LK+G YVPLDP +P ERIAYM++ S V++ A+ L +DV V Sbjct: 2383 MVVGLLAVLKAGGGYVPLDPAYPAERIAYMLQDSAPAAVLAQTAT----QGLLADVSAPV 2438 Query: 2127 IDVAGDSTPAGTADHLSCYKYSDIRKQPVA--RIPSKAASELMYIIYTSGSTGTPKGVMV 2184 I++ SD + Q V ++P ++ L Y+IYTSGSTG PKGVM+ Sbjct: 2439 INL----------------DLSDWQDQSVQNPQVPGLTSAHLAYLIYTSGSTGLPKGVMI 2482 Query: 2185 SQPNVINYLLWSRQQFQLGPQHHMMLVTSISFDISVFEIFGCLSSGATLHVVSSDRLRDP 2244 N +N+L W+ F + TS++FD++V+E F L+SG ++ VV + Sbjct: 2483 EHRNTVNFLTWAHTAFDGSALEKTLFSTSLNFDLAVYECFAPLTSGGSIEVVKN------ 2536 Query: 2245 ALLLAYMNQHKINFWHSVPVLMNQFLFGLSSQDEKEIACL-QHFDTVAIGGEAWSPKLAG 2303 +L +H I ++VP + L E+ L + TV + GEA L Sbjct: 2537 -VLELQHGEHDIGLINTVPSALKALL---------EVNGLPESVHTVNVAGEALKRSLVE 2586 Query: 2304 DIRRSFPRAKLYNLYGPTEATIWATYYEAASDLTGKTVVPLGQPISNNRIFILDKDGNLC 2363 ++ +L NLYGP+E T ++++ A D +G+P+ N + ++LD+ Sbjct: 2587 NLFEKTGVQRLCNLYGPSETTTYSSW--VAMDREHGFAAHIGKPVGNTQFYLLDEQQQPV 2644 Query: 2364 GPGIPGEICISGAGVTPGYFRDEETTAGVFRTHPFTDQ---IVYHTGDIGKYGMGGQLEY 2420 G+ GEI I GAGV GY ++ TA F PF+ Q +Y TGD+G+Y G +EY Sbjct: 2645 PLGVAGEIYIGGAGVARGYLNRDDLTAERFVKDPFSPQPAARMYRTGDLGRYLPDGNIEY 2704 Query: 2421 IAR 2423 + R Sbjct: 2705 LGR 2707 Score = 232 bits (591), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 150/467 (32%), Positives = 240/467 (51%), Gaps = 38/467 (8%) Query: 1960 LTHLINQVIADPEGQLSRYELLDARHKAEIINQFHPLPVPMNPPDQVCRLFEAQVEQNPD 2019 L +L+ + PE L +L + +++ F+ + + +FEAQVE+ P+ Sbjct: 116 LENLLTALEQTPETSLQGLSILPVVEREQLLVAFNDTALDYPQQQTIHGMFEAQVERTPE 175 Query: 2020 QTAVVFEGERVSYRELDELSNQLAAFLVQLEQEPAEPVGVYLGRGIHMIAVLLGILKSGR 2079 AVV +R++YREL++ +N+LA L++ +P VG+ + RG M+ LL ILK+G Sbjct: 176 GVAVVHGEQRLTYRELNQQANRLAHALIKQGVQPDSRVGICVERGAAMVVGLLAILKAGG 235 Query: 2080 PYVPLDPDFPPERIAYMIRHSGLRTVVSDGASIPKLLELASDVLKAVIDVAGDSTPAGTA 2139 YVPLDP +P ERIAYM++ S V++ A+ L +DV VI++ Sbjct: 236 GYVPLDPAYPAERIAYMLQDSAPAAVLAQTAT----QGLLADVSVPVINL---------- 281 Query: 2140 DHLSCYKYSDIRKQPVARIPSKAASELMYIIYTSGSTGTPKGVMVSQPNVINYLLWSRQQ 2199 LS ++ ++ ++P ++ L Y+IYTSGSTG PKGVM+ N +N+L W+ Sbjct: 282 -DLSNWQDESVQN---PQVPGLTSAHLAYLIYTSGSTGLPKGVMIEHRNTVNFLTWAHTA 337 Query: 2200 FQLGPQHHMMLVTSISFDISVFEIFGCLSSGATLHVVSSDRLRDPALLLAYMNQHKINFW 2259 F + TS++FD++V+E F L+SG ++ VV + +L +H I Sbjct: 338 FDGSALEKTLFSTSLNFDLAVYECFAPLTSGGSIEVVKN-------VLELQHGEHDIGLI 390 Query: 2260 HSVPVLMNQFLFGLSSQDEKEIACLQHFDTVAIGGEAWSPKLAGDIRRSFPRAKLYNLYG 2319 ++VP + L D + H TV + GEA L D+ +L NLYG Sbjct: 391 NTVPSALKALL------DVDGLPRSVH--TVNVAGEALKRSLVEDLFERTGVQRLCNLYG 442 Query: 2320 PTEATIWATYYEAASDLTGKTVVPLGQPISNNRIFILDKDGNLCGPGIPGEICISGAGVT 2379 P+E T ++++ A D +G+P+ N + ++LD+ G+ GEI I GAGV Sbjct: 443 PSETTTYSSW--VAMDREQGFAAHIGKPVGNTQFYLLDEQQQPVPLGVSGEIYIGGAGVA 500 Query: 2380 PGYFRDEETTAGVFRTHPFTDQ---IVYHTGDIGKYGMGGQLEYIAR 2423 GY ++ TA F PF+ +Y TGD+G+Y G +EY+ R Sbjct: 501 RGYLNRDDLTAERFLKDPFSQNPAARMYRTGDLGRYLPDGNIEYLGR 547 Score = 208 bits (529), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 188/682 (27%), Positives = 304/682 (44%), Gaps = 70/682 (10%) Query: 1773 HSIAYDGSYIKFTVSEEVTGQLRLLAKNRSSTLYMTVLAIYFLFLKKLSQEEDIIVGFPV 1832 H I + +S + Q R L + +S +++ + L K S +D++ G + Sbjct: 993 HDIEEGCLAVDLELSRRLRAQARQLGVSAASLVHLA----WAQLLSKASGRDDVVFGTVL 1048 Query: 1833 SGREQ--QEWENIIGLFMNMVCIRVDFRELSSFGGVLEEVKRKCLKAYANGRYPFNTLVE 1890 GR Q + E +G+F+N + +RV + GV +R L A + L + Sbjct: 1049 LGRMQGGEGSERALGVFINTLPLRVSLGDQGVRDGVKATHRR--LTALLGHEHASLALAQ 1106 Query: 1891 KLNPERDPSRTPVFSTIFQL-YDNVPQDNDRMSLYD-LSCICKMDGGQIEVRLEYKTSLF 1948 + + P+ P+FS + + +V ++ ++ ++ + + D E R Y +L Sbjct: 1107 RCSGVVAPA--PLFSALLNYRHTSVAVTDETLTAWNGMHALALGD----EERTNYPLTLN 1160 Query: 1949 TEE-------TIQNYACY------------LTHLINQVIADPEGQLSRYELLDARHKAEI 1989 ++ T+Q L++L+N + P+ L +L + ++ Sbjct: 1161 VDDRGEDFLLTVQTVPLIDGARICAYMQQTLSNLVNALEQAPQTPLHAIAILPDSEREQL 1220 Query: 1990 INQFHPLPVPMNPPDQVCRLFEAQVEQNPDQTAVVFEGERVSYRELDELSNQLAAFLVQL 2049 + Q+ + FEA+ Q PD A+VFE + +SY EL+ +NQ+A L+ Sbjct: 1221 LEQWKQPGTAYTSETPIHLQFEARAAQQPDAVALVFEEQTLSYGELNARANQVAHRLLAH 1280 Query: 2050 EQEPAEPVGVYLGRGIHMIAVLLGILKSGRPYVPLDPDFPPERIAYMIRHSGLRTVVSDG 2109 P + V + + RG MI LLGILKSG YVPLDP +P ER+AY + G Sbjct: 1281 GVRPDDRVAICVERGPAMIIGLLGILKSGAGYVPLDPAYPLERLAYTL-----------G 1329 Query: 2110 ASIPKLLELASDVLKAVIDVAGDSTPAGTADHLSCYKYSDIRKQPVA--RIPSKAASELM 2167 S P L L+ ++ + V+ P D D++ + V ++P + L Sbjct: 1330 DSAPVAL-LSQRSVQGTLPVS--QVPVICLD-------DDLQDESVCNPQVPVTPGN-LA 1378 Query: 2168 YIIYTSGSTGTPKGVMVSQPNVINYLLWSRQQFQLGPQHHMMLVTSISFDISVFEIFGCL 2227 Y+IYTSGSTG PKGVM+ NV + + F Q L S +FD SV+EI+G L Sbjct: 1379 YVIYTSGSTGKPKGVMIEHRNVARLFSATEEWFGFNQQDVWALFHSFAFDFSVWEIWGAL 1438 Query: 2228 SSGATLHVVSSDRLRDPALLLAYMNQHKINFWHSVPVLMNQFLFGLSSQDEKEIACLQHF 2287 G L +V R P + + + P Q +++Q E A Sbjct: 1439 LHGGRLLIVPQLVSRSPEDFYNLLCSAGVTVLNQTPSAFRQL---IAAQAENTQA--HSL 1493 Query: 2288 DTVAIGGEAWSPKLAGD--IRRSFPRAKLYNLYGPTEATIWATYYE-AASDLTGKTVVPL 2344 V GGEA + R++ +L N+YG TE T+ TYY D P+ Sbjct: 1494 RQVIFGGEALETAMLKPWYARQANAGTQLVNMYGITETTVHVTYYPLQPEDAQRLGASPI 1553 Query: 2345 GQPISNNRIFILDKDGNLCGPGIPGEICISGAGVTPGYFRDEETTAGVFRTHPFT---DQ 2401 G+ I + ++++LD G G+ GE+ + GAGV GY E TA F +PF+ D Sbjct: 1554 GRRIPDLQLYVLDARGEPVPVGVVGELYVGGAGVARGYLNREALTAERFLDNPFSHTADA 1613 Query: 2402 IVYHTGDIGKYGMGGQLEYIAR 2423 +Y TGD+G++ G LEY+ R Sbjct: 1614 RMYRTGDLGRWLADGSLEYLGR 1635 >ref|NP_522203.1| PROBABLE PEPTIDE SYNTHETASE PROTEIN [Ralstonia solanacearum] emb|CAD17793.1| PROBABLE PEPTIDE SYNTHETASE PROTEIN [Ralstonia solanacearum] Length = 5953 Score = 491 bits (1263), Expect = e-136, Method: Compositional matrix adjust. Identities = 341/1049 (32%), Positives = 519/1049 (49%), Gaps = 76/1049 (7%) Query: 1400 HAFSRALQLEEPRVII--ADIRLDQLDESVTGKLPLQLSPDLRRTGNRFAQPRPVAAAAD 1457 A LQ P ++ A ++L++L + GKL +R P P A Sbjct: 1017 QALREQLQASLPEYMVPAAYVKLERLPLTPNGKL------------DRRGLPAPEGQAYA 1064 Query: 1458 TIAIIGHSGAVISEMEQAVAQLWAKTFGLKKMDISKNFYELGGDSIMATQMANLLNTQLH 1517 + A G E+EQ + +W G++++ +F+ LGG S+ A ++ + TQL Sbjct: 1065 SKAYEAPQG----EVEQTLVGIWQTLLGVERVGRHDDFFALGGHSLQAVRLVAQVRTQLG 1120 Query: 1518 QKLSIAEIFEYPTVSGLAAYLEQSLPSRNEATAKAAGSEAPNA-GYDLSKAQHRIWFLQN 1576 +L + E+F P++S +A + R + TA A + A LS AQ R+WFL Sbjct: 1121 AELGLTELFAQPSLSAVAQAI-----VRGQGTALPAITVADRGEALPLSFAQQRLWFLAQ 1175 Query: 1577 YDPQTTAYHLPVVKQIREAIDLAVLQQGLDILTRRHSSLRTIIKNVNGIPKQFVV-PDKS 1635 + + AYH+PV +++ +D L + LD + RH +LRT + G Q V D Sbjct: 1176 MEGGSEAYHIPVGLRLKGELDAPALLRALDRIVARHEALRTCFEVQEGQAVQRVASADVG 1235 Query: 1636 HVIHFTDYAQEPHXXXXXXXXXXXXNTTAFELEQN-LFRAELHRYEESDYLLYINMHHII 1694 + + D + E F+LEQ L R L + E +++L I MHHI+ Sbjct: 1236 LTLEWVDLSTEAASEHQLGLLAEAEARVPFDLEQGPLIRGRLVKLGEQEHVLLITMHHIV 1295 Query: 1695 SDGWSMGVFFREWMELYDQIRSKRPIQLAPIALQPVDWVEQEKLWIGSGDYLNMERYWMK 1754 SDGWS GV RE LY+ RS L + +Q D+ ++ W+ G YW + Sbjct: 1296 SDGWSQGVLARELGMLYEAYRSGGEDPLPALPIQYADYAVWQRRWLEGGGLQRQGTYWEQ 1355 Query: 1755 ELAQPLPVLELPTDYDRPHSIAYDGSYIKFTVSEEVTGQLRLLAKNRSSTLYMTVLAIYF 1814 LA +L LPTD RP Y G ++ E ++ LR L++ +TL+MTVLA + Sbjct: 1356 ALAGAPTLLSLPTDRARPAQQDYAGGSVEVIFDETLSAGLRKLSQRHGTTLFMTVLAGWS 1415 Query: 1815 LFLKKLSQEEDIIVGFPVSGREQQEWENIIGLFMNMVCIRVDFRELSSFGGVLEEVKRKC 1874 L +LS + +++VG PV+ R + E E +IG F+N + +RV+ ++ +L VK K Sbjct: 1416 ALLSRLSGQGEVVVGSPVANRTRSEVEGLIGFFVNTLALRVEVSG-ATVSELLGRVKAKV 1474 Query: 1875 LKAYANGRYPFNTLVEKLNPERDPSRTPVFSTIFQLYDNVPQDNDRMSLYDLSCICKMDG 1934 L+A A+ PF +VE++ P R S +PVF + N + L L+ I +D Sbjct: 1475 LEAQAHQDLPFEQVVERVRPVRSLSHSPVFQAALS-WLNTEAVGLSLELEGLT-IEGVDA 1532 Query: 1935 GQ--------IEVR---------LEYKTSLFTEETIQNYACYLTHLINQVIADPEGQLSR 1977 GQ +E+R L+Y T+LF ETI+ Y YL L+ ++ + Q+SR Sbjct: 1533 GQAAAKFDLTLELRETSEGLAGSLDYATALFDRETIERYLGYLQRLLAAMVENDSQQVSR 1592 Query: 1978 YELLDARHKAEIINQFHPLPVPMNPPDQVCRLFEAQVEQNPDQTAVVFEGERVSYRELDE 2037 LLD +A+++ ++ + LFEAQV + P+ AV EG +VSY EL+ Sbjct: 1593 IGLLDKDERAQLLESWNETKAAYPDASTIHGLFEAQVRRTPEAIAVEHEGRQVSYAELNA 1652 Query: 2038 LSNQLAAFLVQLEQEPAEPVGVYLGRGIHMIAVLLGILKSGRPYVPLDPDFPPERIAYMI 2097 +N++A L+ L P VG+ GR + ++ LLGILK+G YVPLDP +P +R+ YM+ Sbjct: 1653 RANRVAHALIGLGVGPDARVGLCAGRSVELVVGLLGILKAGGGYVPLDPSYPQDRLTYML 1712 Query: 2098 RHSGLRTVVSDGASIPKLLELASDVLKAVIDVAGDSTPAGTADHLSCYKYSDIRKQPVAR 2157 S V++ G +L L+ VL D+ G P A+H P + Sbjct: 1713 EDSAPVAVLTQGLVREQLGMLSVPVL----DLDG---PQEDAEH-----------DP--Q 1752 Query: 2158 IPSKAASELMYIIYTSGSTGTPKGVMVSQPNVINYLLWSRQQFQLGPQHHMMLVTSISFD 2217 + + L Y+IYTSGSTG PKGVM V+N L W++Q ++L ++ T FD Sbjct: 1753 VEALKPHHLAYVIYTSGSTGRPKGVMNEHRGVVNRLWWAQQTYRLDASDRVLQKTPFGFD 1812 Query: 2218 ISVFEIFGCLSSGATLHVVSSDRLRDPALLLAYMNQHKINFWHSVPVLMNQFLFGLSSQD 2277 +SV+E+F L +GA L + + + PA L A + Q I H VP ++ FL D Sbjct: 1813 VSVWELFWPLLAGARLVMARPEGHKAPAYLAATIEQAGITTLHFVPSMLQLFL------D 1866 Query: 2278 EKEIACLQHFDTVAIGGEAWSPKLAGDIRRSFPRAKLYNLYGPTEATIWATYYEAASDLT 2337 + E Q + GEA L FP ++L+NLYGPTEA I T + +++ Sbjct: 1867 QVEAGRCQGLRRMLCSGEALPHALQQRSLARFPHSELHNLYGPTEAAIDVTAWRCNAEIH 1926 Query: 2338 GKTVVPLGQPISNNRIFILDKDGNLCGPGIPGEICISGAGVTPGYFRDEETTAGVFRTHP 2397 VVP+G+PI+N +I++LD G+ GEI I GAGV GY E TA F +P Sbjct: 1927 -PGVVPIGRPIANTQIYVLDAYRQPVPLGVTGEIYIGGAGVARGYLNRPELTAERFVVNP 1985 Query: 2398 FTD---QIVYHTGDIGKYGMGGQLEYIAR 2423 F + +Y TGD+G++ G LEY R Sbjct: 1986 FHGEGRERMYRTGDLGRWLPDGSLEYQGR 2014 Score = 456 bits (1174), Expect = e-126, Method: Compositional matrix adjust. Identities = 336/1060 (31%), Positives = 521/1060 (49%), Gaps = 86/1060 (8%) Query: 1395 TGTAVHAFSRALQLE----EPRVIIADIRLDQLDESVTGKLPLQLSPDLRRTGNRFAQPR 1450 +G A+ A + QL+ E V A +RL++L + GKL +R P Sbjct: 4186 SGEAIEAQTLREQLQASLPEYMVPAAYVRLERLPLTPNGKL------------DRKELPA 4233 Query: 1451 PVAAAADTIAIIGHSGAVISEMEQAVAQLWAKTFGLKKMDISKNFYELGGDSIMATQMAN 1510 P A + A G E+E A+A +W G++++ +F+ LGG S+ A ++ Sbjct: 4234 PEGQAYASTAYEAPQG----EVEVALAGIWQTLLGVERVGRHDDFFTLGGHSLQAVRLVA 4289 Query: 1511 LLNTQLHQKLSIAEIFEYPTVSGLAAYLEQSLPSRNEATAKAAGSEAPNA-GYDLSKAQH 1569 + TQL +L + E+F P++S +A + R + TA A + A LS AQ Sbjct: 4290 QVRTQLGAELGLTELFAQPSLSAVAQAI-----VRGQGTALPAITVADRGEALPLSFAQQ 4344 Query: 1570 RIWFLQNYDPQTTAYHLPVVKQIREAIDLAVLQQGLDILTRRHSSLRTIIKNVNGIPKQF 1629 R+WFL + + AYH+PV +++ +D L++ LD + RH +LRT + G Q Sbjct: 4345 RLWFLAQMEGGSEAYHIPVGLRLKGELDEEALRRALDRIVARHEALRTRFEVQEGQAVQL 4404 Query: 1630 VVP-DKSHVIHFTDYAQEPHXXXXXXXXXXXXNTTAFELEQN-LFRAELHRYEESDYLLY 1687 +VP D + + D + E T F+LEQ L R L + E +++L Sbjct: 4405 IVPADVGLTLEWVDLSTEEASEHQLGLQAEAEARTPFDLEQGPLIRGRLVKLGEQEHVLL 4464 Query: 1688 INMHHIISDGWSMGVFFREWMELYDQIRSKRPIQLAPIALQPVDWVEQEKLWIGSGDYLN 1747 I MHHI+SDGWS GV RE LY+ RS L + +Q D+ ++ W+ G+ Sbjct: 4465 ITMHHIVSDGWSQGVLARELGTLYEAYRSGGEDPLPALPIQYADYAVWQRRWLEGGELRR 4524 Query: 1748 MERYWMKELAQPLPVLELPTDYDRPHSIAYDGSYIKFTVSEEVTGQLRLLAKNRSSTLYM 1807 YW + LA +L LPTD RP Y G ++ E ++ LR L++ +TL+M Sbjct: 4525 QGTYWEQALAGAPTLLSLPTDRARPAQQDYAGGSVEVIFDETLSAGLRKLSQRHGTTLFM 4584 Query: 1808 TVLAIYFLFLKKLSQEEDIIVGFPVSGREQQEWENIIGLFMNMVCIRVDFRELSSFGGVL 1867 TVLA + + L +LS +++++VG PV+ R + E E +IG F+N + +RV+ + + +L Sbjct: 4585 TVLAGWSVLLSRLSGQDEVVVGSPVANRTRSEVEGLIGFFVNTLALRVEVGGV-TVSELL 4643 Query: 1868 EEVKRKCLKAYANGRYPFNTLVEKLNPERDPSRTPVFSTIFQLYDNVPQDNDRMSLYDLS 1927 VK + L+A A+ PF +VE++ P R S +PVF + N + L L+ Sbjct: 4644 GRVKSRVLEAQAHQDLPFEQVVERVRPVRSLSHSPVFQAALS-WLNTEAVGLSLELEGLT 4702 Query: 1928 CICKMDGGQ--------IEVR---------LEYKTSLFTEETIQNYACYLTHLINQVIAD 1970 I +D GQ +E+R L+Y T+LF ETI+ Y YL L+ + AD Sbjct: 4703 -IEGVDAGQAAAKFDLTLELRETSEGLAGSLDYATALFDRETIERYLGYLQRLLKAMAAD 4761 Query: 1971 PEGQLSRYELLDARHKAEIINQFHPLPVPMNPPDQVCRLFEAQVEQNPDQTAVVFEGERV 2030 ++SR LL +A+++ ++ + LFEAQV + P+ AV EG +V Sbjct: 4762 DSQEVSRIALLGEDERAQLLESWNETKAAYPDASTIHGLFEAQVRRTPEAIAVEHEGRQV 4821 Query: 2031 SYRELDELSNQLAAFLVQLEQEPAEPVGVYLGRGIHMIAVLLGILKSGRPYVPLDPDFPP 2090 SY EL+ +N++A L+ L P VG+ R + ++ LLGILK+G YVPLDP +P Sbjct: 4822 SYAELNARANRVAHALIGLGVGPDARVGLCAERSVELVVGLLGILKAGGGYVPLDPSYPQ 4881 Query: 2091 ERIAYMIRHSGLRTVVSDGASIPKLLELASDVLKAVIDVAGDSTPAGTADHLSCYKYSDI 2150 +R+AYM+ S V++ + +L L+ VL D+A S G A+H Sbjct: 4882 DRLAYMLEDSAPVAVLAQSNTREQLGALSVPVL----DLA--SPLEGEAEH--------- 4926 Query: 2151 RKQPVARIPSKAASELMYIIYTSGSTGTPKGVMVSQPNVINYLLWSRQQFQLGPQHHMML 2210 P ++ + L Y+IYTSGSTG PKGV + + N L W + L L Sbjct: 4927 --DP--QVEALKPHHLAYVIYTSGSTGQPKGVEATIAGLANRLQWFLRDV-LTEAPVTAL 4981 Query: 2211 VTSISFDISVFEIFGCLSSGATLHVVSSDRLRDPALLLAYMNQHKINFWHSVPVLMNQFL 2270 TSI F +V E G L +G +L V + ++D ++ + Q ++ VP L+ Sbjct: 4982 KTSIGFVDAVTETLGTLLAGGSLVVFDNAAVKDLSVFARRLRQTGVSHLVVVPSLLK--- 5038 Query: 2271 FGLSSQDEKEIACLQHFDTVAIGGEAWSPKLAGDIRRSFPRAKLYNLYGPTEATIWATYY 2330 + L S + + L T+ GE +P+LA ++P+ +L N YG +E AT+Y Sbjct: 5039 YLLQSGEPR----LDGLRTLVCSGERLAPELARQCLAAYPQVRLLNFYGSSEVNGDATFY 5094 Query: 2331 EAASDLTGKTVVP----LGQPISNNRIFILDKDGNLCGPGIPGEICISGAGVTPGYFRDE 2386 A G VP +G+PI+N +I+ILD G G+PGEI + GA V GY Sbjct: 5095 RYA----GPEHVPAHSVIGRPIANTQIYILDAYGAPVPIGVPGEIHVGGACVARGYLHRP 5150 Query: 2387 ETTAGVFRTHPFTDQ---IVYHTGDIGKYGMGGQLEYIAR 2423 TA F PF +Y TGD+G + G + Y+ R Sbjct: 5151 GLTAERFVADPFHGDGRARMYRTGDLGCWQADGNIVYLGR 5190 Score = 456 bits (1173), Expect = e-126, Method: Compositional matrix adjust. Identities = 324/1040 (31%), Positives = 508/1040 (48%), Gaps = 84/1040 (8%) Query: 1407 QLEEPRVIIADIRLDQLDESVTGKLPLQLSPDLRRTGNRFAQPRPVAAAADTIAIIGHSG 1466 +L E V A +RL++L + GKL +R P P A + A G Sbjct: 3158 RLPEYMVPAAYVRLERLPLTPNGKL------------DRKELPAPEGQAYASTAYEAPQG 3205 Query: 1467 AVISEMEQAVAQLWAKTFGLKKMDISKNFYELGGDSIMATQMANLLNTQLHQKLSIAEIF 1526 E+E A+A +W G++++ +F+ LGG S+ A ++ + TQL +L + E+F Sbjct: 3206 ----EVEVALAGIWQTLLGVERVGRHDDFFTLGGHSLQAVRLVAQVRTQLGAELGLTELF 3261 Query: 1527 EYPTVSGLAAYLEQSLPSRNEATAKAAGSEAPNAG-YDLSKAQHRIWFLQNYDPQTTAYH 1585 P++S +A + R + TA A + A LS AQ R+WFL + + AYH Sbjct: 3262 AQPSLSAVAQAI-----VRGQGTALPAITVADRGEPLPLSFAQQRLWFLAQMEGGSEAYH 3316 Query: 1586 LPVVKQIREAIDLAVLQQGLDILTRRHSSLRTIIKNVNGIPKQFVV-PDKSHVIHFTDYA 1644 +PV +++ +D L++ LD + RH +LRT G Q V D + D Sbjct: 3317 IPVGLRLKGELDEDALRRSLDRIVARHEALRTRFVTEEGQAVQRVASADVGFALDCVDLQ 3376 Query: 1645 QEPHXXXXXXXXXXXXNTTAFELEQN-LFRAELHRYEESDYLLYINMHHIISDGWSMGVF 1703 + T F+L L R L + E +++L I MHHI+SDGWS GV Sbjct: 3377 GQADREQALATLSEREANTPFDLAHGPLIRGCLVKLGEQEHVLLITMHHIVSDGWSQGVL 3436 Query: 1704 FREWMELYDQIRSKRPIQLAPIALQPVDWVEQEKLWIGSGDYLNMERYWMKELAQPLPVL 1763 RE LY+ R+ L + +Q D+ ++ W+ G+ YW + LA +L Sbjct: 3437 ARELGSLYEAYRAGNADPLPALPIQYADYAVWQRRWLEGGELQRQGTYWEQALAGAPTLL 3496 Query: 1764 ELPTDYDRPHSIAYDGSYIKFTVSEEVTGQLRLLAKNRSSTLYMTVLAIYFLFLKKLSQE 1823 LPTD RP Y G ++ + ++ LR L++ +TL+MTVLA + L +LS + Sbjct: 3497 SLPTDRARPAQQDYAGGSVEVIFDDTLSAGLRKLSQRHGTTLFMTVLAGWSALLSRLSGQ 3556 Query: 1824 EDIIVGFPVSGREQQEWENIIGLFMNMVCIRVDFRELSSFGGVLEEVKRKCLKAYANGRY 1883 E+++VG PV+ R + E E +IG F+N + +RV+ ++ +L VK + L+A A+ Sbjct: 3557 EEVVVGSPVANRTRSEVEGLIGFFVNTLALRVEVSG-ATVSELLGRVKSQVLEAQAHQDL 3615 Query: 1884 PFNTLVEKLNPERDPSRTPVFSTIFQLYDNVPQDNDRMSLYDLSCICKMDGGQ------- 1936 PF +VE++ P R S +PVF + N + L L+ I +D GQ Sbjct: 3616 PFEQVVERVRPVRSLSHSPVFQAALS-WLNTEAVGLSLELEGLT-IEGVDAGQAAAKFDL 3673 Query: 1937 -IEVR---------LEYKTSLFTEETIQNYACYLTHLINQVIADPEGQLSRYELLDARHK 1986 +E+R L+Y T+LF TI+ Y YL L+ ++ + Q+SR LLD + Sbjct: 3674 TLELRETSAGLAGSLDYATALFDRATIERYLGYLQRLLAAMVENDSQQVSRIGLLDEGER 3733 Query: 1987 AEIINQFHPLPVPMNPPDQVCRLFEAQVEQNPDQTAVVFEGERVSYRELDELSNQLAAFL 2046 A+++ ++ + LFEAQV + P+ AVV EG++VSY EL+ +N++A L Sbjct: 3734 AQLLESWNETKAAYPDASTIHGLFEAQVRRTPEAIAVVHEGQQVSYAELNARANRVAHAL 3793 Query: 2047 VQLEQEPAEPVGVYLGRGIHMIAVLLGILKSGRPYVPLDPDFPPERIAYMIRHSGLRTVV 2106 +L P VG+ R + ++ LLGILK+G YVPLDP +P +R+AYM+ S V+ Sbjct: 3794 RRLGVGPDARVGLCAERSVELVIGLLGILKAGGGYVPLDPSYPQDRLAYMLEDSAPVAVL 3853 Query: 2107 SDGASIPKLLELASDVLKAVIDVAGDSTPAGTADHLSCYKYSDIRKQPVARIPSKAASEL 2166 + + +L L+ VL D+ G P A+H P ++ L Sbjct: 3854 AQSNTREQLGALSVPVL----DLDG---PLEEAEH-----------DP--QVTGLEPHHL 3893 Query: 2167 MYIIYTSGSTGTPKGVMVSQPNVINYLLWSRQQFQLGPQHHMMLVTSISFDISVFEIFGC 2226 Y+IYTSGSTG PKGV+V N +N+L W+ + F + TS++FD+SVFE F Sbjct: 3894 AYVIYTSGSTGRPKGVVVEHRNTVNFLAWAARAFPPASLARTLFSTSLNFDLSVFECFAP 3953 Query: 2227 LSSGATLHVVSSDRLRDPALLLAYMNQHKINFWHSVPVLMNQFLFGLSSQDEKEIACLQH 2286 L++G + +V + +L H + ++VP ++ L E+ Sbjct: 3954 LTTGGRIDIVVN-------VLALGDGTHDVRLINTVPSALSALLESSGLDPAVEV----- 4001 Query: 2287 FDTVAIGGEAWSPKLAGDIRRSFPRAKLYNLYGPTEATIWATYYEAASDLTGKTVVPLGQ 2346 V + GEA +L + +LYNLYGP+E T ++++ D +G+ Sbjct: 4002 ---VNVAGEALKRELVERLFAQTQARRLYNLYGPSETTTYSSW--VCMDRQTGFQAHIGR 4056 Query: 2347 PISNNRIFILDKDGNLCGPGIPGEICISGAGVTPGYFRDEETTAGVFRTHPFTD---QIV 2403 PI+N +I++LD G+ GEI I GAGV GY E TA F +PF + + Sbjct: 4057 PIANTQIYVLDAYRQPVPLGVTGEIYIGGAGVARGYLNRPELTAERFVVNPFHGEGRERM 4116 Query: 2404 YHTGDIGKYGMGGQLEYIAR 2423 Y TGD+G++ G LEY R Sbjct: 4117 YRTGDLGRWLPDGSLEYQGR 4136 Score = 253 bits (646), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 267/1092 (24%), Positives = 451/1092 (41%), Gaps = 126/1092 (11%) Query: 1395 TGTAVHAFSRALQLE----EPRVIIADIRLDQLDESVTGKLPLQLSPDLRRTGNRFAQPR 1450 +G A+ A + QL+ E V A +RL+ L + GKL +R P Sbjct: 2064 SGEAIEAQTLREQLQASLPEYMVPAAYVRLEHLPLTPNGKL------------DRKGLPA 2111 Query: 1451 PVAAAADTIAIIGHSGAVISEMEQAVAQLWAKTFGLKKMDISKNFYELGGDSIMATQMAN 1510 P A + A G E+EQ +A +W G++++ +F+ LGG S+ A ++ + Sbjct: 2112 PDGQAYASAAYEAPQG----EVEQTLAGIWQTLLGVERVGRHDDFFALGGHSLQAVRLMS 2167 Query: 1511 LLNTQLHQKLSIAEIFEYPTVSGLAAYLEQS-----------------------LPSRNE 1547 L+ Q + ++ +F PT++G +A + + L S ++ Sbjct: 2168 LVE-QAGWRADVSRLFLQPTLAGFSASITVADAVDIPANRIASGCTRITPSMLPLASLSQ 2226 Query: 1548 ATAKAAGSEAPNAG------YDLSKAQHRIWFLQNYDPQTTAYHLPVVKQIREAIDLAVL 1601 A ++ P Y L+ Q I + Q Y L + ++ L Sbjct: 2227 AAIDRMAAQVPGGAANIEDIYPLAPLQEGILYHHLMAKQRDPYLLFAMFRMDSRARLEAF 2286 Query: 1602 QQGLDILTRRHSSLRTII------KNVNGIPKQFVVPDKSHVIHFTDYAQEPHXXXXXXX 1655 QGL L RH+ LRT + + + + +Q + + + D Sbjct: 2287 AQGLQSLIARHTILRTAVIWDGLDEPMQVVWRQAALERQQMRLDAADGDIATQLKQRFDQ 2346 Query: 1656 XXXXXNTTAFELEQNLFRAELHRYEESDYLLYINMHHIISDGWSMGVFFREWMELYDQIR 1715 + L + +F + R ++ + HH+I D SM +W+ + R Sbjct: 2347 GLHGLDLRQAPLMRLVFAEDAAR---GGWVAMLVFHHMIDDATSM-----KWLHTELEAR 2398 Query: 1716 SKRPIQLAPIALQPVDWVEQEKLWIGSGDYLNMERYWMKELAQPLPVLELPTDYDRPHSI 1775 + P A+ ++V + + I + R + ++ +P L +I Sbjct: 2399 LANEARHLPRAIPFRNYVARTRQAIAGNAHEAFFREMLADVVEPTLPFGLQDARGDDLAI 2458 Query: 1776 AYDGSYIKFTVSEEVTGQLRLLAKNRSSTLYMTVLAIYFLFLKKLSQEEDIIVGFPVSGR 1835 + +S + Q RLL + +S ++ + + S +D++ G + GR Sbjct: 2459 GQATRRLSGPLSRRLRQQARLLKVSAASLHHLA----WARVVSATSGRDDVVFGTVLMGR 2514 Query: 1836 EQ--QEWENIIGLFMNMVCIRVDFRE-LSSFGGVLEEVKRKCLKAYANGRYPFNTLVEKL 1892 Q + E+ +G+F+N + +RV + + S G V+ L + + L E Sbjct: 2515 SQGGRGAEHTVGMFINTLPLRVLLDDRMVSAGARDTHVRLPALMGHE-----YAPLAEAQ 2569 Query: 1893 NPERDPSRTPVFSTIFQLYDNVPQDN-----------------DRMSLYDLSCICKMDGG 1935 + P+F + N+PQ D + Y L+ + G Sbjct: 2570 RCSGVAAPQPLFGALLNYRQNMPQPEPAGQVSAAWTGIDVLGMDERTNYPLTAVVDDLGE 2629 Query: 1936 QIEVRLEYKTSLFTEETIQNYACYLTHLINQVIADPEGQLSRYELLDARHKAEIINQFHP 1995 + ++ + E + L L+ + L +L + + I+ ++ Sbjct: 2630 DFGLIVQSVPGMDAERIVGYLETALASLVASLERGGRESLRSLTVLPEAERHQQIDGWNR 2689 Query: 1996 LPVPMNPPDQVCRLFEAQVEQNPDQTAVVFEGERVSYRELDELSNQLAAFLVQLEQEPAE 2055 + L EAQ + P+ AV +SYRELD +N+LA L+ P Sbjct: 2690 TQAAYASASTLPGLVEAQAARTPEAIAVEHGASTLSYRELDSQANRLAHRLIARGVVPDA 2749 Query: 2056 PVGVYLGRGIHMIAVLLGILKSGRPYVPLDPDFPPERIAYMIRHSGLRTVVSDGASIPKL 2115 VG+ + RG+ M+ +LGILK+G YVPLDP +P +R+AYM+ S VV+ + +L Sbjct: 2750 RVGLCVERGLPMVIGVLGILKAGGSYVPLDPSYPRDRLAYMLEDSAPVAVVAQSGTRDRL 2809 Query: 2116 LELASDVLKAVIDVAGDSTPAGTADHLSCYKYSDIRKQPVARIPSKAASELMYIIYTSGS 2175 D AV+D+ D S ++ + VA + S A+ Y+IYTSGS Sbjct: 2810 ----GDRPVAVVDL----------DEAS-WQAEPSHRPEVAGLSSHHAA---YVIYTSGS 2851 Query: 2176 TGTPKGVMVSQPNVINYLLWSRQQFQLGPQHHMMLVTSISFDISVFEIFGCLSSGATLHV 2235 TG PKGV V V+N L R + VT++ FDI+ E++ L SGA + V Sbjct: 2852 TGRPKGVTVEHRQVVNLLESMRGLLAMTEADRWPAVTTLGFDIAGLELYLPLISGAVVIV 2911 Query: 2236 VSSDRLRDPALLLAYMNQHKINFWHSVPVLMNQFL-FGLSSQDEKEIACLQHFDTVAIGG 2294 + + R+ L A + + P L G S + + C GG Sbjct: 2912 LDREVSRNAQSLSAALEGSGATVMQATPSTWRLLLESGWSGRPGLKALC---------GG 2962 Query: 2295 EAWSPKLAGDIRRSFPRAKLYNLYGPTEATIWATYYEAASDLTGKTVVPLGQPISNNRIF 2354 EA +LAG +R R L+N+YGPTE TIW++ E + G+ VVP+G+PI+N +++ Sbjct: 2963 EALPGELAGRLRARVGR--LWNVYGPTETTIWSSAREVDATDAGQGVVPIGRPIANTQMY 3020 Query: 2355 ILDKDGNLCGPGIPGEICISGAGVTPGYFRDEETTAGVFRTHPFTD---QIVYHTGDIGK 2411 +LD G+ GE+ I GAGV GY E TA F +PF + +Y TGD+G+ Sbjct: 3021 VLDAYRQPVPLGVTGEVYIGGAGVARGYLNRPELTAERFVENPFHGEGRERMYRTGDLGR 3080 Query: 2412 YGMGGQLEYIAR 2423 + G LEY R Sbjct: 3081 WLPDGSLEYQGR 3092 Score = 145 bits (367), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 155/628 (24%), Positives = 260/628 (41%), Gaps = 60/628 (9%) Query: 1820 LSQEEDIIVGFPVSGREQ--QEWENIIGLFMNMVCIRVDFRELSSFGGVLEEVKRKCLKA 1877 LS +D++ G + GR Q + E +GLF+N + +RV G R L A Sbjct: 363 LSGRDDVVFGTVLLGRLQGGRSAERALGLFINTLPLRVAVHGQDVLAGTRAVHAR--LSA 420 Query: 1878 YANGRYPFNTLVEKLNPERDPSRTPVFSTIFQLYD-----------------NVPQDNDR 1920 + L ++ + P P+FS + +V + +R Sbjct: 421 LLGHEHAPLALAQRCSGVAAPQ--PLFSALLNYRHSAAPAASAATAPTWSGIDVLEMKER 478 Query: 1921 MSLYDLSCICKMDGGQIEVRLEYKTSLFTEETIQNYACYLTHLINQVIADPEGQLSRYEL 1980 + Y L+ G E+ ++ + E L L + L + Sbjct: 479 TN-YPLTVSVDDLGDGFELNVQSAAGIDPERIAGYLETALVSLTEALERGGREPLHSLTV 537 Query: 1981 LDARHKAEIINQFHPLPVPMNPPDQVCRLFEAQVEQNPDQTAVVFEGER-VSYRELDELS 2039 L + ++ +++ + LFEAQV + P+ A+ +GER +SYR L+ L+ Sbjct: 538 LPVAERQLLLARWNETAADSARQASLSGLFEAQVVRAPEAIAIE-QGERQLSYRALNALA 596 Query: 2040 NQLAAFLVQLEQEPAEPVGVYLGRGIHMIAVLLGILKSGRPYVPLDPDFPPERIAYMIRH 2099 N+LA L + +P + V + L R I ++A L ILK G YVPLD + P R+ +++ Sbjct: 597 NRLAWRLREAGVKPGDRVAILLERSIELVASELAILKCGAVYVPLDCNAPQARLRFLLED 656 Query: 2100 -SGLRTVVSDGASIPKLLELASDVLKAVIDVAGDSTPAGTADHLSCYKYSDIRKQPVARI 2158 + + G +P L L +DV G + + L Sbjct: 657 VEAALLLTASGLDVPVLAGLRR------LDVDGAAGNSAVDADLP--------------- 695 Query: 2159 PSKAASELMYIIYTSGSTGTPKGVMVSQPNVINYLLWSRQQFQLGPQHHMMLVTSISFDI 2218 P Y++YTSGSTG PKGV+V I+ L+ + M ++ +FD Sbjct: 696 PVPGGEAAAYVLYTSGSTGLPKGVVVPH-RAISRLVLNNGYAAFCADDRMAFASNPAFDA 754 Query: 2219 SVFEIFGCLSSGATLHVVSSDRLRDPALLLAYMNQHKINFWHSVPVLMNQFLFGLSSQDE 2278 S +++ L +G + ++ + P + + +++ +Q+ L Sbjct: 755 STLDVWVPLLNGGRVVIIDQPTVLAPERFAQALRRGQVSVLWMTAGQFHQYAPSL----- 809 Query: 2279 KEIACLQHFDTVAIGGEAWSPKLAGDIRRSFPRAKLYNLYGPTEATIWATYYEAASDLTG 2338 I + +GG+ P + R L N YGPTE T +AT + + G Sbjct: 810 --IGVFPQLRYLMVGGDVLDPATIAMVLREGAPQHLLNGYGPTETTTFATTHLIQAVAAG 867 Query: 2339 KTVVPLGQPISNNRIFILDKDGNLCGPGIPGEICISGAGVTPGYFRDEETTAGVFRTHPF 2398 + +P+G+PI+N +I++LD G+ GEI + GAGV GY E TA F +PF Sbjct: 868 RG-IPIGRPIANTQIYVLDAYQQPVPLGVTGEIYVGGAGVGLGYLNRPELTAERFVVNPF 926 Query: 2399 TD---QIVYHTGDIGKYGMGGQLEYIAR 2423 + +Y TGD+G++ G LEY R Sbjct: 927 HGEGRERMYKTGDLGRWLPDGSLEYQGR 954 >pir||JX0340 gramicidin S synthase 2 - Bacillus brevis dbj|BAA06146.1| gramicidin S synthetase 2 [Brevibacillus brevis] Length = 4450 Score = 489 bits (1258), Expect = e-136, Method: Compositional matrix adjust. Identities = 314/972 (32%), Positives = 504/972 (51%), Gaps = 67/972 (6%) Query: 1470 SEMEQAVAQLWAKTFGLKKMDISKNFYELGGDSIMATQMANLLNTQLHQKLSIAEIFEYP 1529 +E+E+ +A++W + G+ ++ I NF+ LGG S+ A + + +N + + + + +FE P Sbjct: 974 NELEEKLAKIWEEVLGISQIGIQDNFFSLGGHSLKAITLISRMNKECNVDIPLRLLFEAP 1033 Query: 1530 TVSGLAAYLEQSLPSRNEATAKAAGSEAPNAGYDLSKAQHRIWFLQNYDPQTTAYHLPVV 1589 T+ ++ Y+ + A E Y +S Q R++ L +D TAY+LP V Sbjct: 1034 TIQEISNYINGAKKESYVAIQPVPEQEY----YPVSSVQKRMFILNEFDRSGTAYNLPGV 1089 Query: 1590 KQIREAIDLAVLQQGLDILTRRHSSLRTIIKNVNGIPKQFVVPDKSHVIHFTDYAQEPHX 1649 + ++ L+ + L RH +LRT ++NG P Q V + I +++ ++ Sbjct: 1090 MFLDGKLNYRQLEAAVKKLVERHEALRTSFHSINGEPVQRVHQNVELQIAYSESTED--- 1146 Query: 1650 XXXXXXXXXXXNTTAFELE-QNLFRAELHRYEESDYLLYINMHHIISDGWSMGVFFREWM 1708 F LE L R L + E +L ++MHHIISDG SM + +E Sbjct: 1147 ---QVERIIAEFMQPFALEVAPLLRVGLVKLEAERHLFIMDMHHIISDGVSMQIMIQEIA 1203 Query: 1709 ELYDQIRSKRPIQLAPIALQPVDWVEQEKLWIGSGDYLNMERYWMKELAQPLPVLELPTD 1768 +LY + +L + +Q D+ + S E YW+ + +PVL LPTD Sbjct: 1204 DLY------KEKELPTLGIQYKDFTVWHNRLLQSDVIEKQEAYWLNVFTEEIPVLNLPTD 1257 Query: 1769 YDRPHSIAYDGSYIKFTVSEEVTGQLRLLAKNRSSTLYMTVLAIYFLFLKKLSQEEDIIV 1828 Y RP ++DG F+ +++ L +A +TLYM +LA Y +FL K S ++DI+V Sbjct: 1258 YPRPTIQSFDGKRFTFSTGKQLMDDLYKVATETGTTLYMVLLAAYNVFLSKYSGQDDIVV 1317 Query: 1829 GFPVSGREQQEWENIIGLFMNMVCIRVDFRELSSFGGVLEEVKRKCLKAYANGRYPFNTL 1888 G P++GR + EN++G+F+N + IR +F L VK+ L AY N YPF+TL Sbjct: 1318 GTPIAGRSHADVENMLGMFVNTLAIRSRLNNEDTFKDFLANVKQTALHAYENPDYPFDTL 1377 Query: 1889 VEKLNPERDPSRTPVFSTIFQLYDN---------------VPQDNDRMSLYDLSCICKMD 1933 VEKL +RD SR P+F T+F L + VP N R S +DL+ + Sbjct: 1378 VEKLGIQRDLSRNPLFDTMFVLQNTDRKSFEVEQITITPYVP--NSRHSKFDLTLEVSEE 1435 Query: 1934 GGQIEVRLEYKTSLFTEETIQNYACYLTHLINQVIADPEGQLSRYELLDARHKAEIINQF 1993 +I + LEY T LFT++T++ A + +++ ++ +P +S E+L K I+ +F Sbjct: 1436 QNEILLCLEYCTKLFTDKTVERMAGHFLQILHAIVGNPTIIISEIEILSEEEKQHILFEF 1495 Query: 1994 HPLPVPMNPPDQVCRLFEAQVEQNPDQTAVVFEGERVSYRELDELSNQLAAFLVQLEQEP 2053 + + LFE QVE+ PD AV ++ + ++YREL+E +NQ+A L Q +P Sbjct: 1496 NDTKTTYPHMQTIQGLFEEQVEKTPDHVAVGWKDQALTYRELNERANQVARVLRQKGVQP 1555 Query: 2054 AEPVGVYLGRGIHMIAVLLGILKSGRPYVPLDPDFPPERIAYMIRHSGLRTVVSDGASIP 2113 VG+ + R M+ ++GILK+G Y+PLDP++P +RI+YMI+ G+R +++ Sbjct: 1556 DNIVGLLVERSPEMLVGIMGILKAGGAYLPLDPEYPADRISYMIQDCGVRIMLTQ----Q 1611 Query: 2114 KLLELASDVLKAVIDVAGDSTPAGTADHLSCYKYSDIRKQPVARIPSKAASELMYIIYTS 2173 LL L D VI + DS G + +L+ P A +L YI+YTS Sbjct: 1612 HLLSLVHDEFDCVI-LDEDSLYKGDSSNLA---------------PVNQAGDLAYIMYTS 1655 Query: 2174 GSTGTPKGVMVSQPNVINYLLWSRQQFQLGPQHHMMLVTSISFDISVFEIFGCLSSGATL 2233 GSTG PKGVMV NVI L+ + Q+ ++ +I FD FE+FG L GA L Sbjct: 1656 GSTGKPKGVMVEHRNVIR-LVKNTNYVQVREDDRIIQTGAIGFDALTFEVFGSLLHGAEL 1714 Query: 2234 HVVSSDRLRDPALLLAYMNQHKIN-FWHSVPVLMNQFLFGLSSQDEKEIACLQHFDTVAI 2292 + V+ D L D L ++ ++I W + P L NQ LS E+ A L+ ++ + Sbjct: 1715 YPVTKDVLLDAEKLHKFLQANQITIMWLTSP-LFNQ----LSQGTEEMFAGLR---SLIV 1766 Query: 2293 GGEAWSPKLAGDIRRSFPRAKLYNLYGPTEATIWATYYEAASDLTGKTVVPLGQPISNNR 2352 GG+A SPK +++R P ++N YGPTE T ++T + + +P+G+ ISN+ Sbjct: 1767 GGDALSPKHINNVKRKCPNLTMWNGYGPTENTTFSTCFLIDKEYDDN--IPIGKAISNST 1824 Query: 2353 IFILDKDGNLCGPGIPGEICISGAGVTPGYFRDEETTAGVFRTHPFT-DQIVYHTGDIGK 2411 ++I+D+ G L G+PGE+C+ G GV GY T F +PF + +Y TGD+ + Sbjct: 1825 VYIMDRYGQLQPVGVPGELCVGGDGVARGYMNQPALTEEKFVPNPFAPGERMYRTGDLAR 1884 Query: 2412 YGMGGQLEYIAR 2423 + G +EY+ R Sbjct: 1885 WLPDGTIEYLGR 1896 Score = 463 bits (1191), Expect = e-128, Method: Compositional matrix adjust. Identities = 291/999 (29%), Positives = 498/999 (49%), Gaps = 62/999 (6%) Query: 1442 TGNRFAQPRPVAAAADTIAIIGHSGAVISEMEQAVAQLWAKTFGLKKMDISKNFYELGGD 1501 T N R + +I+I A + +E + ++W GL+++ I +F+ +GG Sbjct: 3026 TANGKIDKRSLPEPDGSISIGTEYVAPRTMLEGKLEEIWKDVLGLQRVGIHDDFFTIGGH 3085 Query: 1502 SIMATQMANLLNTQLHQKLSIAEIFEYPTVSGLAAYLEQSLPSRNEATAKAAGSEAPNAG 1561 S+ A + + ++ + ++ + +FE PT+ GLA Y+E++ + A +G + Sbjct: 3086 SLKAMAVISQVHKECQTEVPLRVLFETPTIQGLAKYIEETDTEQYMAIQPVSGQDY---- 3141 Query: 1562 YDLSKAQHRIWFLQNYDPQTTAYHLPVVKQIREAIDLAVLQQGLDILTRRHSSLRTIIKN 1621 Y +S AQ R++ + +D +Y++P + I ++ L+ L RH SLRT + Sbjct: 3142 YPVSSAQKRMFIVNQFDGVGISYNMPSIMLIEGKLERTRLESAFKRLIERHESLRTSFEI 3201 Query: 1622 VNGIPKQFVVPDKSHVIHFTDYAQEPHXXXXXXXXXXXXNTTAFELEQNLFRAELHRYEE 1681 +NG P Q + + + + + E + A L R EL + EE Sbjct: 3202 INGKPVQKIHEEADFNMSYQVASNEQVEKMIDEFIQPFDLSVA-----PLLRVELLKLEE 3256 Query: 1682 SDYLLYINMHHIISDGWSMGVFFREWMELYDQIRSKRPIQLAPIALQPVDWVEQEKLWIG 1741 ++L +MHHIISDG S + +E ELY + L + +Q D+ + W Sbjct: 3257 DRHVLIFDMHHIISDGISSNILMKELGELY------QGNALPELRIQYKDFAVWQNEWFQ 3310 Query: 1742 SGDYLNMERYWMKELAQPLPVLELPTDYDRPHSIAYDGSYIKFTVSEEVTGQLRLLAKNR 1801 S + E YW+ A P+L++PTDY RP ++DG+ + F +++ L +A Sbjct: 3311 SEAFKKQEEYWVNVFADERPILDIPTDYPRPMQQSFDGAQLTFGTGKQLMDGLYRVATET 3370 Query: 1802 SSTLYMTVLAIYFLFLKKLSQEEDIIVGFPVSGREQQEWENIIGLFMNMVCIRVDFRELS 1861 +TLYM +LA Y + L K S +EDIIVG P+ GR + ENI+G+F+N + +R Sbjct: 3371 GTTLYMVLLAAYNVLLSKYSGQEDIIVGTPIVGRSHTDLENIVGMFVNTLAMRNKPEGEK 3430 Query: 1862 SFGGVLEEVKRKCLKAYANGRYPFNTLVEKLNPERDPSRTPVFSTIFQLYDNVPQDNDRM 1921 +F + E+K+ L A+ N YPF L+EKL +RD SR P+F T+F L N+ +++ + Sbjct: 3431 TFKAFVSEIKQNALAAFENQDYPFEELIEKLEIQRDLSRNPLFDTLFSL-QNIGEESFEL 3489 Query: 1922 ----------------SLYDLSCICKMDGGQIEVRLEYKTSLFTEETIQNYACYLTHLIN 1965 + +DLS + +I L+Y T L+ E+T++ A + ++ Sbjct: 3490 AELTCKPFDLVSKLEHAKFDLSLVAVEKEEEIAFGLQYCTKLYKEKTVEQLAQHFIQIVK 3549 Query: 1966 QVIADPEGQLSRYELLDARHKAEIINQFHPLPVPMNPPDQVCRLFEAQVEQNPDQTAVVF 2025 ++ +P+ +LS ++L K +I+ +F+ + + LFE QV++ P+ A+V+ Sbjct: 3550 AIVENPDVKLSDIDMLSEEEKKQIMLEFNDTKIQYPQNQTIQELFEEQVKKTPEHIAIVW 3609 Query: 2026 EGERVSYRELDELSNQLAAFLVQLEQEPAEPVGVYLGRGIHMIAVLLGILKSGRPYVPLD 2085 EG+ ++Y EL+ +NQLA L + P PV + R + MI + ILK+G YVP+D Sbjct: 3610 EGQALTYHELNIKANQLARVLREKGVTPNHPVAIMTERSLEMIVGIFSILKAGGAYVPID 3669 Query: 2086 PDFPPERIAYMIRHSGLRTVVSDGASIPKLLELASDVLKAVIDVAGDSTPAGTADHLSCY 2145 P +P ERI Y++ SG +++ + K L D+ +D+ + +L Sbjct: 3670 PAYPQERIQYLLEDSGATLLLTQSHVLNK---LPVDI--EWLDLTDEQNYVEDGTNLPFM 3724 Query: 2146 KYSDIRKQPVARIPSKAASELMYIIYTSGSTGTPKGVMVSQPNVINYLLWSRQQFQLGPQ 2205 S ++L YIIYTSG+TG PKGVM+ ++IN L W +++++ GP Sbjct: 3725 NQS---------------TDLAYIIYTSGTTGKPKGVMIEHQSIINCLQWRKEEYEFGPG 3769 Query: 2206 HHMMLVTSISFDISVFEIFGCLSSGATLHVVSSDRLRDPALLLAYMNQHKINFWHSVPVL 2265 + V S +FD V +F + +GAT + + +DP L + +I ++ VP L Sbjct: 3770 DTALQVFSFAFDGFVASLFAPILAGATSVLPKEEEAKDPVALKKLIASEEITHYYGVPSL 3829 Query: 2266 MNQFLFGLSSQDEKEIACLQHFDTVAIGGEAWSPKLAGDIRRSFPRAKLYNLYGPTEATI 2325 + L SS+D LQ+ V +GGE ++ I+ ++ N YGPTE ++ Sbjct: 3830 FSAILDVSSSKD------LQNLRCVTLGGEKLPAQIVKKIKEKNKEIEVNNEYGPTENSV 3883 Query: 2326 WATYYEAASDLTGKTVVPLGQPISNNRIFILDKDGNLCGPGIPGEICISGAGVTPGYFRD 2385 T D+ + + +G P+SN ++I++ + L G+ GE+CI G G+ GY Sbjct: 3884 VTT---IMRDIQVEQEITIGCPLSNVDVYIVNCNHQLQPVGVVGELCIGGQGLARGYLNK 3940 Query: 2386 EETTAGVFRTHPFT-DQIVYHTGDIGKYGMGGQLEYIAR 2423 E TA F +PF + +Y TGD+ K+ G +EY+ R Sbjct: 3941 PELTADKFVVNPFVPGERMYKTGDLAKWRSDGMIEYVGR 3979 Score = 448 bits (1153), Expect = e-124, Method: Compositional matrix adjust. Identities = 309/1038 (29%), Positives = 519/1038 (50%), Gaps = 76/1038 (7%) Query: 1417 DIRLDQLDESVTGKLPLQLSPD---------LRRTG--NRFAQPRPVAAAADTIAIIGHS 1465 ++ + +L E + +LP+ + P L + G NR A P+P + S Sbjct: 1949 EVTVSELREYIAKELPVYMVPAYFVQIEQMPLTQNGKVNRSALPKPDGEFGTATEYVAPS 2008 Query: 1466 GAVISEMEQAVAQLWAKTFGLKKMDISKNFYELGGDSIMATQMANLLNTQLHQKLSIAEI 1525 S++E +A++W G+ K+ + NF+ELGG S+ A M + ++ + +L + + Sbjct: 2009 ----SDIEMKLAEIWHNVLGVNKIGVLDNFFELGGHSLRAMTMISQVHKEFDVELPLKVL 2064 Query: 1526 FEYPTVSGLAAYLEQSLPSRNEATAKAAGSEAPNAGYDLSKAQHRIWFLQNYDPQTTAYH 1585 FE PT+S LA Y+ + A P Y +S AQ R++ L ++ Y+ Sbjct: 2065 FETPTISALAQYIADG----EKGMYLAIQPVTPQDYYPVSSAQKRMYILYEFEGAGITYN 2120 Query: 1586 LPVVKQIREAIDLAVLQQGLDILTRRHSSLRTIIKNVNGIPKQFVVPDKSHVIHFTDYAQ 1645 +P V I +D + + L RH +LRT ++NG P Q V + I +++ + Sbjct: 2121 VPNVMFIEGKLDYQRFEYAIKSLINRHEALRTSFYSLNGEPVQRVHQNVELQIAYSEAKE 2180 Query: 1646 EPHXXXXXXXXXXXXNTTAFELE-QNLFRAELHRYEESDYLLYINMHHIISDGWSMGVFF 1704 + F+LE R L + +L ++MHHIISDG SM + Sbjct: 2181 D------EIEQIVESFVQPFDLEIAPALRVGLVKLASDRHLFLMDMHHIISDGVSMQIIT 2234 Query: 1705 REWMELYDQIRSKRPIQLAPIALQPVDWVEQEKLWIGSGDYLNMERYWMKELAQPLPVLE 1764 +E +LY + +LA + +Q D+ + W S + YW+ A+ +PVL Sbjct: 2235 KEIADLY------KGKELAELHIQYKDFAVWQNEWFQSAALEKQKTYWLNTFAEDIPVLN 2288 Query: 1765 LPTDYDRPHSIAYDGSYIKFTVSEEVTGQLRLLAKNRSSTLYMTVLAIYFLFLKKLSQEE 1824 L TDY RP +++G + F+ +++ +L+ LA +TLYM +LA Y + L K S +E Sbjct: 2289 LSTDYPRPTIQSFEGDIVTFSAGKQLAEELKRLATETGTTLYMLLLAAYNVLLHKYSGQE 2348 Query: 1825 DIIVGFPVSGREQQEWENIIGLFMNMVCIRVDFRELSSFGGVLEEVKRKCLKAYANGRYP 1884 +I+VG P++GR + ENI+G+F+N + ++ + +F L EVK+ L+A+ N YP Sbjct: 2349 EIVVGTPIAGRSHADVENIVGMFVNTLALKNTPIAVRTFHEFLLEVKQNALEAFENQDYP 2408 Query: 1885 FNTLVEKLNPERDPSRTPVFSTIFQLYDNVPQDND------RMSLYDLSC-ICKMD---- 1933 F L+EKL RD SR P+F T+F L N+ + + S Y++ I K D Sbjct: 2409 FENLIEKLQVRRDLSRNPLFDTMFSL-SNIDEQVEIGIEGLSFSPYEMQYWIAKFDISFD 2467 Query: 1934 ----GGQIEVRLEYKTSLFTEETIQNYACYLTHLINQVIADPEGQLSRYELLDARHKAEI 1989 I+ Y T+LF +ETI+ A + H++ +++ +PE +L +L + + Sbjct: 2468 ILEKQDDIQFYFNYCTNLFKKETIERLATHFMHILQEIVINPEIKLCEINMLSEEEQQRV 2527 Query: 1990 INQFHPLPVPMNPPDQVCRLFEAQVEQNPDQTAVVFEGERVSYRELDELSNQLAAFLVQL 2049 + F+ LFE QVE+ PD AV+ E E++SY+EL+ +NQLA L Q Sbjct: 2528 LYDFNGTDATYATNKIFHELFEEQVEKTPDHIAVIDEREKLSYQELNAKANQLARVLRQK 2587 Query: 2050 EQEPAEPVGVYLGRGIHMIAVLLGILKSGRPYVPLDPDFPPERIAYMIRHSGLRTVVSDG 2109 +P VG+ + R + MI +LG+LK+G YVP+D D+P ERI+YM+ SG Sbjct: 2588 GVQPNSMVGIMVDRSLDMIVGMLGVLKAGGAYVPIDIDYPQERISYMMEDSG-------- 2639 Query: 2110 ASIPKLLELASDVLKAVIDVAGDSTPAGTADHLSCYKYSDIRKQPVARIPSKAASELMYI 2169 L L L I +GD + L + S++ +P+AR ++ YI Sbjct: 2640 ----AALLLTQQKLTQQIAFSGDILYLDQEEWLH-EEASNL--EPIAR-----PQDIAYI 2687 Query: 2170 IYTSGSTGTPKGVMVSQPNVINYLLWSRQQFQLGP-QHHMMLVTSISFDISVFEIFGCLS 2228 IYTSG+TG PKGVM+ + +N + + ++L ++ + S +FD+S + L Sbjct: 2688 IYTSGTTGKPKGVMIEHQSYVNVAMAWKDAYRLDTFPVRLLQMASFAFDVSAGDFARALL 2747 Query: 2229 SGATLHVVSSDRLRDPALLLAYMNQHKINFWHSVPVLMNQFLFGLSSQDEKEIACLQHFD 2288 +G L V ++ DPA L A + ++ I + + P L+ + + Q + +I+ LQ Sbjct: 2748 TGGQLIVCPNEVKMDPASLYAIIKKYDITIFEATPALVIPLMEYIYEQ-KLDISQLQ--- 2803 Query: 2289 TVAIGGEAWSPK-LAGDIRRSFPRAKLYNLYGPTEATIWATYYEA-ASDLTGKTVVPLGQ 2346 + +G ++ S + + R ++ N YG TEA I ++YYE S L VP+G+ Sbjct: 2804 ILIVGSDSCSMEDFKTLVSRFGSTIRIVNSYGVTEACIDSSYYEQPLSSLHVTGTVPIGK 2863 Query: 2347 PISNNRIFILDKDGNLCGPGIPGEICISGAGVTPGYFRDEETTAGVFRTHPFT-DQIVYH 2405 P +N +++I+++ + G+ GE+CI GAGV GY + TA F +PF + +Y Sbjct: 2864 PYANMKMYIMNQYLQIQPVGVIGELCIGGAGVARGYLNRPDLTAEKFVPNPFVPGEKLYR 2923 Query: 2406 TGDIGKYGMGGQLEYIAR 2423 TGD+ ++ G +E++ R Sbjct: 2924 TGDLARWMPDGNVEFLGR 2941 Score = 309 bits (791), Expect = 7e-82, Method: Compositional matrix adjust. Identities = 239/886 (26%), Positives = 415/886 (46%), Gaps = 61/886 (6%) Query: 1562 YDLSKAQHRIWFLQNYDPQTTAYHLPVVKQIREAIDLAVLQQGLDILTRRHSSLRT-IIK 1620 Y LS Q + F D A+ + + I +D+ +L + L+IL R+ RT + Sbjct: 13 YRLSPMQEGMLFHALLDKDKNAHLVQMSIAIEGIVDVELLSESLNILIDRYDVFRTTFLH 72 Query: 1621 NVNGIPKQFVVPDKSHVIHFTDYAQ--EPHXXXXXXXXXXXXNTTAFELEQN-LFRAELH 1677 P Q V+ ++ + F D + E T F+L ++ L R + Sbjct: 73 EKIKQPLQVVLKERPVQLQFKDISSLDEEKREQAIEQYKYQDGETVFDLTRDPLMRVAIF 132 Query: 1678 RYEESDYLLYINMHHIISDGWSMGVFFREWMELYDQIRSKRPIQLAPIALQPVDWVEQEK 1737 + + +Y + + HHI+ DGW + F + +Y ++ K+P+QL A+QP +Q Sbjct: 133 QTGKVNYQMIWSFHHILMDGWCFNIIFNDLFNIYLSLKEKKPLQLE--AVQPY---KQFI 187 Query: 1738 LWIGSGDYLNMERYWMKELAQPLPVLELPTDYDRPHSIAYDGSYIKFTVSEEVTGQLRLL 1797 W+ D RYW + L + LP ++ Y+ + +F + +T QL + Sbjct: 188 KWLEKQDKQEALRYWKEHLMNYDQSVTLPKKKAAINNTTYEPAQFRFAFDKVLTQQLLRI 247 Query: 1798 AKNRSSTLYMTVLAIYFLFLKKLSQEEDIIVGFPVSGR--EQQEWENIIGLFMNMVCIRV 1855 A TL + I+ + L+K + D++ G VSGR E E ++GLF+N + +R+ Sbjct: 248 ANQSQVTLNIVFQTIWGIVLQKYNSTNDVVYGSVVSGRPSEISGIEKMVGLFINTLPLRI 307 Query: 1856 DFRELSSFGGVLEEVKRKCLKAYANGRYPFNTLVEKLNPERDPSRTPVFSTIFQLYDNVP 1915 ++ SF +++ V + L + + +P + +++ + + L + + Sbjct: 308 QTQKDQSFIELVKTVHQNVLFSQQHEYFPLYEIQNHTELKQNLIDHIMVIENYPLVEEL- 366 Query: 1916 QDNDRM---------------SLYDLSCICKMDGGQIEVRLEYKTSLFTEETIQNYACYL 1960 Q N M + YD++ + + +I VRL+Y +++ + I+ ++ Sbjct: 367 QKNSIMQKVGFTVRDVKMFEPTNYDMTVMV-LPRDEISVRLDYNAAVYDIDFIRKIEGHM 425 Query: 1961 THLINQVIADPEGQLSRYELLDARHKAEIINQFHPLPVPMNPPDQVCRLFEAQVEQNPDQ 2020 + V +P + LL + K ++ + H + P + +LF QVE+ P+ Sbjct: 426 KEVALCVANNPHVLVQDVPLLTKQEKQHLLVELHD-SITEYPDKTIHQLFTEQVEKTPEH 484 Query: 2021 TAVVFEGERVSYRELDELSNQLAAFLVQLEQEPAEPVGVYLGRGIHMIAVLLGILKSGRP 2080 AVVFE E+V+YREL E SNQLA FL + + +G+ + R + MI +LGILK+G Sbjct: 485 VAVVFEDEKVTYRELHERSNQLARFLREKGVKKESIIGIMMERSVEMIVGILGILKAGGA 544 Query: 2081 YVPLDPDFPPERIAYMIRHSGLRTVVSDGASIPKLLELASDVLKAVIDVAGDSTPAGTAD 2140 +VP+DP++P ERI YM+ +R V++ + L+ K I + S + Sbjct: 545 FVPIDPEYPKERIGYML--DSVRLVLTQ-----RHLKDKFAFTKETIVIEDPSISHELTE 597 Query: 2141 HLSCYKYSDIRKQPVARIPSKAASELMYIIYTSGSTGTPKGVMVSQPNVINYLLWSRQQF 2200 + S+ +L YIIYTSG+TG PKGVM+ N++N L ++ ++ Sbjct: 598 EIDYINESE---------------DLFYIIYTSGTTGKPKGVMLEHKNIVNLLHFTFEKT 642 Query: 2201 QLGPQHHMMLVTSISFDISVFEIFGCLSSGATLHVVSSDRLRDPALLLAYMNQHKINFWH 2260 + ++ T+ SFD+ EIF L SG L+++ + RD L + + I Sbjct: 643 NINFSDKVLQYTTCSFDVCYQEIFSTLLSGGQLYLIRKETQRDVEQLFDLVKRENIEVL- 701 Query: 2261 SVPVLMNQFLFGLSSQDEKEIACLQHFDTVAIGGEAWSPKLAGDIRRSFPR--AKLYNLY 2318 S PV +F+F + C++H T GE + + +R L+N Y Sbjct: 702 SFPVAFLKFIFNEREFINRFPTCVKHIIT---AGEQLV--VNNEFKRYLHEHNVHLHNHY 756 Query: 2319 GPTEATIWATYYEAASDLTGKTVVPLGQPISNNRIFILDKDGNLCGPGIPGEICISGAGV 2378 GP+E + T Y + + P+G+PISN I+ILD++ L GI GE+ ISGA V Sbjct: 757 GPSETHV-VTTYTINPEAEIPELPPIGKPISNTWIYILDQEQQLQPQGIVGELYISGANV 815 Query: 2379 TPGYFRDEETTAGVFRTHPFT-DQIVYHTGDIGKYGMGGQLEYIAR 2423 GY ++E TA F PF ++ +Y TGD+ ++ G +E++ R Sbjct: 816 GRGYLNNQELTAEKFFADPFRPNERMYRTGDLARWLPDGNIEFLGR 861 >ref|ZP_00106169.1| COG1020: Non-ribosomal peptide synthetase modules and related proteins [Nostoc punctiforme] Length = 1432 Score = 488 bits (1256), Expect = e-136, Method: Compositional matrix adjust. Identities = 308/973 (31%), Positives = 493/973 (50%), Gaps = 47/973 (4%) Query: 1470 SEMEQAVAQLWAKTFGLKKMDISKNFYELGGDSIMATQMANLLNTQLHQKLSIAEIFEYP 1529 + +E+ +A +WA ++++ + NF+ELGG S++ATQ+ + + T +L + +FE Sbjct: 350 TPIEEILAPIWADVLRVEQIGVYDNFFELGGHSLLATQLVSRIRTTFKIELPLRSLFEAA 409 Query: 1530 TVSGLAAYLEQSLPSRNEATAKAAGSEAPNAGYDLSKAQHRIWFLQNYDPQTTAYHLPVV 1589 T++ LA Y++Q + +E A N LS AQ R+WFL DP + AY++P Sbjct: 410 TIANLAEYIQQYQRNSSELLIPPLQPVARNENIPLSFAQQRLWFLNQLDPNSAAYNIPGA 469 Query: 1590 KQIREAIDLAVLQQGLDILTRRHSSLRTIIKNVNGIPKQFVVPDKSHVIHFTDYAQEP-- 1647 + +++A L+Q L + RRH +LRT G Q + P S + D P Sbjct: 470 VSFQGQLNVAALEQSLSEIIRRHEALRTNFITQAGEAVQIIRPVSSWTMTVIDLQDLPAD 529 Query: 1648 HXXXXXXXXXXXXNTTAFEL-EQNLFRAELHRYEESDYLLYINMHHIISDGWSMGVFFRE 1706 F+L ++L R L E++ +L MHHI+SDGWSMGVF +E Sbjct: 530 EREIEIQQLATVAAQQPFDLVNESLIRTTLLAISETENILLFCMHHIVSDGWSMGVFVQE 589 Query: 1707 WMELYDQIRSKRPIQLAPIALQPVDWVEQEKLWIGSGDYLNMERYWMKELAQPLPVLELP 1766 ELY L +A+Q D+ ++ W+ + YW ++LA +LELP Sbjct: 590 VAELYTAFSQGHLSSLPELAIQYADFAVWQRQWLQGEVKESQINYWREQLAGAPALLELP 649 Query: 1767 TDYDRPHSIAYDGSYIKFTVSEEVTGQLRLLAKNRSSTLYMTVLAIYFLFLKKLSQEEDI 1826 TD RP + G+ F++SEE++ L LL++ TL+MT+LA + L + + + DI Sbjct: 650 TDRPRPAVQTFRGTTQSFSLSEELSQALSLLSRQEGVTLFMTLLAAFDTLLHRYTGQTDI 709 Query: 1827 IVGFPVSGREQQEWENIIGLFMNMVCIRVDFRELSSFGGVLEEVKRKCLKAYANGRYPFN 1886 +VG ++ R E E +IG F+N + R D SF +LE V+ L+A+ + PF Sbjct: 710 LVGSAIANRNYSEIEGLIGFFVNTLVFRTDVSGNPSFRQLLERVREVSLEAHTHQDLPFE 769 Query: 1887 TLVEKLNPERDPSRTPVFSTIFQLYDNVPQDNDRMSLYDLSCIC---------------K 1931 LVE L PERD S TP+F +F ++ N P + + LS + Sbjct: 770 LLVEALQPERDLSHTPLFQVMF-VFQNTPTSDIELPGLTLSSLTTESLTAKFDLTLAFEN 828 Query: 1932 MDGGQIEVRLEYKTSLFTEETIQNYACYLTHLINQVIADPEGQLSRYELLDARHKAEIIN 1991 D G + EY T LF TI + L+ ++ +PE +S+ LL + +++N Sbjct: 829 TDQGLVGA-WEYNTDLFDTLTIARMIGHFQTLLESIVTNPEQPVSQLPLLTVNEQHQLLN 887 Query: 1992 QFHPLPVPMNPPDQVCRLFEAQVEQNPDQTAVVFEGERVSYRELDELSNQLAAFLVQLEQ 2051 +++ + LF AQ E+NPD A VF ++++Y+EL+ +NQLA +L L Sbjct: 888 EWNNTQTEYPQNQCIHELFTAQAERNPDLVAAVFGSQQITYQELNSRANQLAHYLRTLGV 947 Query: 2052 EPAEPVGVYLGRGIHMIAVLLGILKSGRPYVPLDPDFPPERIAYMIRHSGLRTVVSDGAS 2111 VG+++ R + M+ LLGILK+G YVPLDPD+P ER++ M+ S + +++ Sbjct: 948 GTEVLVGIFVERSLEMLVGLLGILKAGGAYVPLDPDYPQERLSLMLADSQVPVLLTQQRL 1007 Query: 2112 IPKLLELASDVLKAVIDVAGDSTPAGTADHLSCYKYSDIRKQPVARIPSKA-ASELMYII 2170 + KL E V+ +D D I ++ A + S+ A +L Y+I Sbjct: 1008 VEKLPEYGQPVV--CLDTGWDI----------------INRESTANLHSEVTADKLAYVI 1049 Query: 2171 YTSGSTGTPKGVMVSQPNVINYLLWSRQQFQLGPQHHMMLVTSISFDISVFEIFGCLSSG 2230 YTSGSTG PKGV V +N L+++ QL + + SFD + FEI+G L G Sbjct: 1050 YTSGSTGKPKGVAVPH-RAVNRLVFNTNYIQLDANDCIAQAANASFDAATFEIWGALLHG 1108 Query: 2231 ATLHVVSSDRLRDPALLLAYMNQHKINFWHSVPVLMNQFLFGLSSQDEKEIACLQHFDTV 2290 A L V+ + P AY+ + +I+ L NQ L+S + L++ + Sbjct: 1109 ARLVGVTHNIALSPQEFAAYIREQEISVLFLTTALFNQ----LASFVPQAFNTLRY---L 1161 Query: 2291 AIGGEAWSPKLAGDIRRSFPRAKLYNLYGPTEATIWATYYEAASDLTGKTVVPLGQPISN 2350 GGEA P+ ++ ++ L ++YGPTE+T +++++ T +P+GQPISN Sbjct: 1162 LFGGEAVDPRWVKEVLQNGAPQHLLHVYGPTESTTFSSWFLIEDVPATATTIPIGQPISN 1221 Query: 2351 NRIFILDKDGNLCGPGIPGEICISGAGVTPGYFRDEETTAGVFRTHPFTDQIVYHTGDIG 2410 +I++LD++ G+PGE+ I G G+ GY E T F +PF + +Y TGD+G Sbjct: 1222 TQIYLLDQNLQPVPIGVPGELYIGGDGLAQGYLNRLELTQEKFIANPFNNSKLYKTGDLG 1281 Query: 2411 KYGMGGQLEYIAR 2423 +Y G +EY+AR Sbjct: 1282 RYLPDGNIEYLAR 1294 Score = 99.8 bits (247), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 71/232 (30%), Positives = 112/232 (48%), Gaps = 23/232 (9%) Query: 2200 FQLGPQHHMMLVTSISFDISVFEIFGCLSSGATLHVVSSDRLRDPALLLAYMNQHKINFW 2259 F L P ++ S SFD S++E+ L SGA L++ + + L L+ + + I Sbjct: 19 FDLLPSSRILQFASFSFDASIWEVVMALGSGARLYLGTKESLLPGLELIELLRDYGITHI 78 Query: 2260 HSVPVLMNQFLFGLSSQDEKEIACLQHFDTVAIGGEAWSPKLAGDIRRSFPRAKLYNLYG 2319 P L+ + E+ LQ+ + + GEA +P L I++ + +N YG Sbjct: 79 TLPPS-------ALAVLPQAELPALQN---IIVAGEACAPDL---IKQWSVGRRFFNAYG 125 Query: 2320 PTEATIWATYYEAAS-DLTGKTVVPLGQPISNNRIFILDKDGNLCGPGIPGEICISGAGV 2378 PTE T+ AT E + + + K P+G+PI N + +ILD G+PGE+ I GAGV Sbjct: 126 PTETTVCATVAECGNGERSDKP--PIGRPIPNTQAYILDSYLQPVPIGVPGELHIGGAGV 183 Query: 2379 TPGYFRDEETTAGVFRTHPFT-------DQIVYHTGDIGKYGMGGQLEYIAR 2423 GY + T F +PF + +Y TGD+ +Y G +EY+ R Sbjct: 184 AQGYLNRPDLTQEKFIPNPFNNSKFKIQNSKLYKTGDLARYLPDGNIEYLGR 235 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.136 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 3,607,853,240 Number of extensions: 155577244 Number of successful extensions: 380146 Number of sequences better than 1.0e-05: 3757 Number of HSP's gapped: 363171 Number of HSP's successfully gapped: 6163 Length of query: 2437 Length of database: 757,237,578 Length adjustment: 142 Effective length of query: 2295 Effective length of database: 371,693,520 Effective search space: 853036628400 Effective search space used: 853036628400 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 135 (56.6 bits)