BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0472.0022.p (232 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_470750.1| two-component response regulator [Listeria inno... 218 1e-55 gb|AAF73970.1| putative response regulator Rra [Lactococcus lact... 214 8e-55 ref|NP_267750.1| two-component system regulator [Lactococcus lac... 214 1e-54 ref|NP_664048.1| two-component response regulator [Streptococcus... 214 2e-54 ref|NP_606584.1| CovR [Streptococcus pyogenes MGAS8232] >gi|1974... 212 6e-54 >ref|NP_470750.1| two-component response regulator [Listeria innocua] ref|NP_464902.1| two-component response regulator [Listeria monocytogenes EGD-e] pir||AE1609 two-component response regulator lisR [imported] - Listeria innocua (strain Clip11262) pir||AI1246 two-component response regulator lisR [imported] - Listeria monocytogenes (strain EGD-e) emb|CAC99455.1| two-component response regulator [Listeria monocytogenes] emb|CAC96645.1| two-component response regulator [Listeria innocua] Length = 226 Score = 218 bits (554), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 120/225 (53%), Positives = 155/225 (68%), Gaps = 3/225 (1%) Query: 10 MNRILLIEDEKNLARFIELELQHVSYSVTLVQDXXXXXXXXXXXXWDXXXXXXXXXXXNG 69 MNRIL++EDEKNLARFIELELQH +Y + D WD NG Sbjct: 1 MNRILIVEDEKNLARFIELELQHENYETAVANDGRAGLELALNEEWDAILLDLMLPHLNG 60 Query: 70 IELCRRLRQEKQTPVIIITARDGLSDKINGLDSGADDYIAKPFAIEELLARMRSLLRRTG 129 +E+CRR+RQ KQTP+I+ITARD + D+++GLD GADDYI KPFAIEELLAR+RSLLRR Sbjct: 61 VEVCRRVRQVKQTPIIMITARDSVIDRVSGLDHGADDYIVKPFAIEELLARLRSLLRRVE 120 Query: 130 SLCQGQ---LLVCQDLQLDPLGRTLTKSGEALELTKREFDILLVLMQNMGRVMTREKLME 186 + Q L ++L ++ R + + E ++LTKRE+++LL LM+N+ V+TRE L+ Sbjct: 121 NAEQSAKQTTLQYRNLIVEKENRIVKRDEEIIDLTKREYELLLTLMENVNIVLTREVLLN 180 Query: 187 SVWGYETEVDMKVVDVYISYLRGKIDTPGEPSIVQTLRGLGYVIR 231 VWGYETEV+ VVDVY+ YLR KID P E S +QT+RG GYV+R Sbjct: 181 KVWGYETEVETNVVDVYVRYLRNKIDHPDEESYIQTVRGTGYVMR 225 >gb|AAF73970.1| putative response regulator Rra [Lactococcus lactis subsp. cremoris] Length = 230 Score = 214 bits (546), Expect = 8e-55, Method: Compositional matrix adjust. Identities = 107/224 (47%), Positives = 148/224 (66%), Gaps = 3/224 (1%) Query: 12 RILLIEDEKNLARFIELELQHVSYSVTLVQDXXXXXXXXXXXXWDXXXXXXXXXXXNGIE 71 +IL+IEDEKNLARF+ LEL+H Y+ + + +D +G E Sbjct: 5 KILIIEDEKNLARFVSLELEHEGYATEIKDNGRSGIEEATSKDYDLILLDLMLPELDGFE 64 Query: 72 LCRRLRQEKQTPVIIITARDGLSDKINGLDSGADDYIAKPFAIEELLARMRSLLRRT--- 128 + RRLR+EK TP+I++TARD D++ GLD GADDYI KPFAIEELLAR+R+ RR Sbjct: 65 VARRLRKEKDTPIIMMTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRAFFRREEHG 124 Query: 129 GSLCQGQLLVCQDLQLDPLGRTLTKSGEALELTKREFDILLVLMQNMGRVMTREKLMESV 188 ++ + + +DL +D RT+ + + ++LT+RE+D+LL LMQN+G V+TRE L+ V Sbjct: 125 HAVERAENTSFRDLVIDKTNRTVHRGKKVIDLTRREYDLLLTLMQNVGDVVTREHLVSQV 184 Query: 189 WGYETEVDMKVVDVYISYLRGKIDTPGEPSIVQTLRGLGYVIRK 232 WGYE + VVDVYI YLR KID G+ S +QT+RGLGYV+R+ Sbjct: 185 WGYEEGTETNVVDVYIRYLRNKIDVEGQDSYIQTVRGLGYVMRE 228 >ref|NP_267750.1| two-component system regulator [Lactococcus lactis subsp. lactis] pir||B86824 two-component system regulator llrA [imported] - Lactococcus lactis subsp. lactis (strain IL1403) gb|AAK05692.1| two-component system regulator [Lactococcus lactis subsp. lactis] Length = 230 Score = 214 bits (546), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 107/224 (47%), Positives = 148/224 (66%), Gaps = 3/224 (1%) Query: 12 RILLIEDEKNLARFIELELQHVSYSVTLVQDXXXXXXXXXXXXWDXXXXXXXXXXXNGIE 71 +IL+IEDEKNLARF+ LEL+H Y+ + + +D +G E Sbjct: 5 KILIIEDEKNLARFVSLELEHEGYATEIKDNGRSGLEEATSKDYDLILLDLMLPELDGFE 64 Query: 72 LCRRLRQEKQTPVIIITARDGLSDKINGLDSGADDYIAKPFAIEELLARMRSLLRRT--- 128 + RRLR+EK TP+I++TARD D++ GLD GADDYI KPFAIEELLAR+R+ RR Sbjct: 65 VARRLRKEKDTPIIMMTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRAFFRREEHG 124 Query: 129 GSLCQGQLLVCQDLQLDPLGRTLTKSGEALELTKREFDILLVLMQNMGRVMTREKLMESV 188 ++ + + +DL +D RT+ + + ++LT+RE+D+LL LMQN+G V+TRE L+ V Sbjct: 125 HAVERAENTSFRDLVIDKTNRTVHRGKKVIDLTRREYDLLLTLMQNVGDVVTREHLVSQV 184 Query: 189 WGYETEVDMKVVDVYISYLRGKIDTPGEPSIVQTLRGLGYVIRK 232 WGYE + VVDVYI YLR KID G+ S +QT+RGLGYV+R+ Sbjct: 185 WGYEEGTETNVVDVYIRYLRNKIDVEGQDSYIQTVRGLGYVMRE 228 >ref|NP_664048.1| two-component response regulator [Streptococcus pyogenes MGAS315] gb|AAC64935.1| CsrR [Streptococcus pyogenes] gb|AAM78851.1| two-component response regulator [Streptococcus pyogenes MGAS315] Length = 228 Score = 214 bits (544), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 108/227 (47%), Positives = 151/227 (66%), Gaps = 3/227 (1%) Query: 9 LMNRILLIEDEKNLARFIELELQHVSYSVTLVQDXXXXXXXXXXXXWDXXXXXXXXXXXN 68 + +IL+IEDEKNLARF+ LELQH Y V + + +D + Sbjct: 1 MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALEKEFDLILLDLMLPEMD 60 Query: 69 GIELCRRLRQEKQTPVIIITARDGLSDKINGLDSGADDYIAKPFAIEELLARMRSLLRRT 128 G E+ RRL+ EK T ++++TARD + D + GLD GADDYI KPFAIEELLAR+R++ RR Sbjct: 61 GFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQ 120 Query: 129 GSLCQGQLL---VCQDLQLDPLGRTLTKSGEALELTKREFDILLVLMQNMGRVMTREKLM 185 + ++ + +DL L+P R++ + + + LTKRE+D+L +LM NM RVMTRE+L+ Sbjct: 121 DIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREYDLLNILMTNMNRVMTREELL 180 Query: 186 ESVWGYETEVDMKVVDVYISYLRGKIDTPGEPSIVQTLRGLGYVIRK 232 +VW Y+ V+ VVDVYI YLRGKID PG+ S +QT+RG+GYVIR+ Sbjct: 181 SNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIRE 227 >ref|NP_606584.1| CovR [Streptococcus pyogenes MGAS8232] gb|AAL97083.1| CovR [Streptococcus pyogenes MGAS8232] Length = 228 Score = 212 bits (539), Expect = 6e-54, Method: Compositional matrix adjust. Identities = 108/227 (47%), Positives = 150/227 (66%), Gaps = 3/227 (1%) Query: 9 LMNRILLIEDEKNLARFIELELQHVSYSVTLVQDXXXXXXXXXXXXWDXXXXXXXXXXXN 68 + +IL+IEDEKNLARF+ LELQH Y V + + +D + Sbjct: 1 MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALEKEFDLILLDLMLPEMD 60 Query: 69 GIELCRRLRQEKQTPVIIITARDGLSDKINGLDSGADDYIAKPFAIEELLARMRSLLRRT 128 G E+ RRL+ EK T ++++TARD + D + GLD GADDYI KPFAIEELLAR+R+ RR Sbjct: 61 GFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRATFRRQ 120 Query: 129 GSLCQGQLL---VCQDLQLDPLGRTLTKSGEALELTKREFDILLVLMQNMGRVMTREKLM 185 + ++ + +DL L+P R++ + + + LTKRE+D+L +LM NM RVMTRE+L+ Sbjct: 121 DIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEIPLTKREYDLLNILMTNMNRVMTREELL 180 Query: 186 ESVWGYETEVDMKVVDVYISYLRGKIDTPGEPSIVQTLRGLGYVIRK 232 +VW Y+ V+ VVDVYI YLRGKID PG+ S +QT+RG+GYVIR+ Sbjct: 181 SNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIRE 227 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.321 0.140 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 284,960,992 Number of extensions: 9588827 Number of successful extensions: 35715 Number of sequences better than 1.0e-05: 3103 Number of HSP's gapped: 32390 Number of HSP's successfully gapped: 3105 Length of query: 232 Length of database: 757,237,578 Length adjustment: 122 Effective length of query: 110 Effective length of database: 425,995,500 Effective search space: 46859505000 Effective search space used: 46859505000 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 124 (52.4 bits)