BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0471.0014.p (246 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00097260.1| COG0745: Response regulators consisting of a ... 238 1e-61 ref|NP_347090.1| Response regulator (CheY-like and HTH domains) ... 180 3e-44 ref|NP_782042.1| transcriptional regulatory component of sensory... 174 1e-42 ref|NP_782495.1| regulatory component of sensory transduction sy... 165 8e-40 ref|NP_691278.1| two-component response regulator [Oceanobacillu... 158 1e-37 >ref|ZP_00097260.1| COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Desulfitobacterium hafniense] Length = 228 Score = 238 bits (607), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 115/223 (51%), Positives = 154/223 (69%) Query: 19 MKTLLIVEDDRSLNKGIALTLAQNDLAIQQAYDITSAEQILSSNKXXXXXXXXHLPDGSG 78 + +LIVEDD +L++GI L N+ A Q ++T A Q + + +LPDG+G Sbjct: 4 INKILIVEDDLALSEGIVLAFKDNNFAFVQTRNLTEARQAVRNTSIQLVILDLNLPDGNG 63 Query: 79 LDYCEKIRRTSQVPIIFLTANDMEPDIVTGFELGGDDYITKPFSLMILRARVMAVLKRTA 138 L++ +++RRTS VP+I LTAND+E D+V G ELG DDYITKPFSLMILRARV A L+ Sbjct: 64 LEFLKELRRTSAVPVIILTANDLETDVVRGLELGADDYITKPFSLMILRARVNARLRNAH 123 Query: 139 SRGEDKITLGPLSFDFGKLEFYKNKEQLILSKTELKLLKILVTNPGTILTREQLIDRIWT 198 D + + F F K+EF K+ + LSKTE KLL++L+ N G LTR QL+D IWT Sbjct: 124 PSAGDTVEIEGFCFSFAKMEFAKDGVPIELSKTEQKLLRLLLENRGQTLTRAQLVDAIWT 183 Query: 199 QEAEFVDENALTVAVKRLRTKIEDEPAAPKYIKTVYGLGYMWA 241 + AE+VDENAL+V V RLR K+ED P++P++IKTVYG+GY WA Sbjct: 184 EGAEYVDENALSVTVNRLRNKLEDLPSSPRFIKTVYGIGYTWA 226 >ref|NP_347090.1| Response regulator (CheY-like and HTH domains) [Clostridium acetobutylicum] pir||C96955 response regulator (CheY-like and HTH domains) [imported] - Clostridium acetobutylicum gb|AAK78430.1| Response regulator (CheY-like and HTH domains) [Clostridium acetobutylicum] Length = 227 Score = 180 bits (456), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 93/223 (41%), Positives = 137/223 (61%), Gaps = 2/223 (0%) Query: 19 MKTLLIVEDDRSLNKGIALTLAQNDLAIQQAYDITSAEQILSSNKXXXXXXXXHLPDGSG 78 M +L+VEDD +L+ GI TL + I A+++ ++ K LPDGSG Sbjct: 1 MAKILLVEDDEALSMGIKYTLLSEKFEVIATSSIEEAKEVFNNEKISLVLMDLMLPDGSG 60 Query: 79 LDYCEKIRRTSQVPIIFLTANDMEPDIVTGFELGGDDYITKPFSLMILRARVMAVLKRTA 138 D C ++R+ S +PIIFLTA D E ++V GF+LG DDYITKPF + L +R+ AVL+R + Sbjct: 61 YDLCRELRKNSDIPIIFLTACDEEVNVVMGFDLGADDYITKPFKIKELISRIKAVLRRCS 120 Query: 139 SRGE-DKITLGPLSFDFGKLEFYKNKEQLILSKTELKLLKILVTNPGTILTREQLIDRIW 197 SR E ++ + D L+ YKN ++++L+ ELKLL + + N G L R ++ R+W Sbjct: 121 SREEVSELKSRDVLIDKRTLKAYKNDKEIVLTHMELKLLILFIENSGQTLKRNLILQRLW 180 Query: 198 TQEAEFVDENALTVAVKRLRTKIEDEPAAPKYIKTVYGLGYMW 240 EFVD+N L+V +KRLR K++++ P YI TV G+GY W Sbjct: 181 DISEEFVDDNTLSVYIKRLREKLKEDSKNP-YIVTVRGIGYRW 222 >ref|NP_782042.1| transcriptional regulatory component of sensory transduction system [Clostridium tetani E88] gb|AAO35979.1| transcriptional regulatory component of sensory transduction system [Clostridium tetani E88] Length = 230 Score = 174 bits (442), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 94/226 (41%), Positives = 134/226 (59%), Gaps = 6/226 (2%) Query: 19 MKTLLIVEDDRSLNKGIALTLAQNDLAIQQAYDITSAEQILSSNKXXXXXXXXHLPDGSG 78 M +L+VEDD L I TL ++ A I A N LPDG+G Sbjct: 1 MNNILLVEDDSILAYSIEYTLNGEGFNLKCADSIKKARDNFKENSFDLIILDVMLPDGNG 60 Query: 79 LDYCEKIRRTSQVPIIFLTANDMEPDIVTGFELGGDDYITKPFSLMILRARVMAVLKR-- 136 D+C++IR+ S+VP+IFLTA D E ++V G ++G DDYITKPF + L +R+ A+L+R Sbjct: 61 YDFCKEIRKASEVPVIFLTACDEEANVVIGLDIGADDYITKPFRIKELISRIRAILRRSK 120 Query: 137 TASRGEDKITLGPLSFDF--GKLEFYKNKEQLILSKTELKLLKILVTNPGTILTREQLID 194 T S+ D + G + GK+E KN +++IL+ E +LL I + +P IL+R +++ Sbjct: 121 TFSKDLDLLISGDIKVQTLQGKIE--KNDKEIILTALEYRLLLIFINHPKQILSRNIILE 178 Query: 195 RIWTQEAEFVDENALTVAVKRLRTKIEDEPAAPKYIKTVYGLGYMW 240 +W E EFVD+N L+V ++RLR KIED PKYI T GLGY W Sbjct: 179 ELWDAEGEFVDDNTLSVYIRRLREKIEDNAGEPKYITTHRGLGYRW 224 >ref|NP_782495.1| regulatory component of sensory transduction system [Clostridium tetani E88] gb|AAO36432.1| regulatory component of sensory transduction system [Clostridium tetani E88] Length = 228 Score = 165 bits (418), Expect = 8e-40, Method: Compositional matrix adjust. Identities = 86/220 (39%), Positives = 126/220 (57%), Gaps = 1/220 (0%) Query: 19 MKTLLIVEDDRSLNKGIALTLAQNDLAIQQAYDITSAEQILSSNKXXXXXXXXHLPDGSG 78 MK + +VEDD+++ + + L L + A + A L+ NK LPDG+G Sbjct: 1 MKRIFLVEDDKAIARNLMLLLRSEGFTVTHAPTRSEAFAALAGNKFDLALIDISLPDGNG 60 Query: 79 LDYCEKIRRTSQVPIIFLTANDMEPDIVTGFELGGDDYITKPFSLMILRARVMAVLKRTA 138 C +I+ T VP+IFLTA+ E +VTG +G DDYITKPF L AR+ L+++ Sbjct: 61 FTVCTEIKETQDVPVIFLTASGDEASVVTGLNMGADDYITKPFRSRELIARIGTALRKSG 120 Query: 139 SRGEDKITLGPLSFDFGKLEFYKNKEQLILSKTELKLLKILVTNPGTILTREQLIDRIWT 198 R + L D KN ++ LS E +LL + ++NP +I+TR +L+D +W Sbjct: 121 -RSRSDFEIRGLHVDTASGIVKKNGNEVFLSALEYRLLLVFISNPKSIITRGRLLDELWD 179 Query: 199 QEAEFVDENALTVAVKRLRTKIEDEPAAPKYIKTVYGLGY 238 EFV++N LTV +KRLR KIE++PA+P+ I TV G GY Sbjct: 180 AAGEFVNDNTLTVYIKRLREKIENDPASPQIILTVRGTGY 219 >ref|NP_691278.1| two-component response regulator [Oceanobacillus iheyensis HTE831] dbj|BAC12313.1| two-component response regulator [Oceanobacillus iheyensis HTE831] Length = 256 Score = 158 bits (399), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 83/237 (35%), Positives = 139/237 (58%), Gaps = 8/237 (3%) Query: 10 MRQNKGAEAMKTLLIVEDDRSLNKGIALTLAQNDLAIQQAYDITSAEQILSSN--KXXXX 67 + +K E +LIVEDD+++ G+ +L Q + + + A++ ++++ Sbjct: 10 LETSKVDECNMNILIVEDDKTIATGLEYSLKQEGYDVVVCHKVQEAQRKINNDLDDISLC 69 Query: 68 XXXXHLPDGSGLDYCEKIRRTSQVPIIFLTANDMEPDIVTGFELGGDDYITKPFSLMILR 127 LPDGSG + CE ++R + +P+IFLT D E ++V G ++G DDYITKPF + L Sbjct: 70 LFDLSLPDGSGYELCEMVKRKADIPVIFLTVVDDEVNVVMGLDMGADDYITKPFRIRELI 129 Query: 128 ARVMAVLKRTASRGEDK------ITLGPLSFDFGKLEFYKNKEQLILSKTELKLLKILVT 181 +R+ VL+R +K I++G ++ + + YK E+++L+ E +LL I V Sbjct: 130 SRIKTVLRRYEKSKPNKEQLSSVISIGSINIHTLEGKVYKETEEILLTALEYRLLMIFVN 189 Query: 182 NPGTILTREQLIDRIWTQEAEFVDENALTVAVKRLRTKIEDEPAAPKYIKTVYGLGY 238 + G +L+R+QL+ IW +FV++N LTV +KRLR KIE++ P I+TV G+GY Sbjct: 190 HRGQVLSRKQLLQLIWDIAGDFVNDNTLTVYIKRLRKKIEEDAQHPTVIETVRGMGY 246 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.318 0.135 0.380 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 327,286,452 Number of extensions: 11911119 Number of successful extensions: 38451 Number of sequences better than 1.0e-05: 3032 Number of HSP's gapped: 35411 Number of HSP's successfully gapped: 3034 Length of query: 246 Length of database: 757,237,578 Length adjustment: 122 Effective length of query: 124 Effective length of database: 425,995,500 Effective search space: 52823442000 Effective search space used: 52823442000 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 124 (52.4 bits)