BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0454.0005.p (525 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_241989.1| BH1123~unknown conserved protein [Bacillus halo... 201 3e-50 ref|NP_623880.1| AraC-type DNA-binding domain-containing protein... 177 5e-43 ref|NP_563003.1| two-component response regulator [Clostridium p... 165 2e-39 ref|NP_242975.1| BH2109~unknown conserved protein [Bacillus halo... 164 4e-39 ref|NP_621980.1| CheY-like receiver domains [Thermoanaerobacter ... 161 5e-38 >ref|NP_241989.1| BH1123~unknown conserved protein [Bacillus halodurans] pir||C83790 hypothetical protein BH1123 [imported] - Bacillus halodurans (strain C-125) dbj|BAB04842.1| BH1123~unknown conserved protein [Bacillus halodurans] Length = 526 Score = 201 bits (512), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 152/544 (27%), Positives = 260/544 (47%), Gaps = 55/544 (10%) Query: 5 ALLVDDEDFVLDGLKEAIDWKKYGINIAGAVNNGREALEFLEHSGITIDIVFTDIKMPVM 64 +++DDE+ V+ GLK+ I WK G G NGR L+ + + + IV TDI MP+M Sbjct: 4 VVIIDDEEHVVRGLKKIISWKALGCECVGEAANGRRGLDIVRET--SPHIVLTDIYMPIM 61 Query: 65 DGFGLTEALKSAEYPCKIIVLTGHEEFEFAKKAIRYGIFDYLLKPVELESIELTIDRLVK 124 G + + L+ + ++++L+G+ EFE A+KA++ I DYL KP +++IE + R++ Sbjct: 62 YGLDMIQILREDGFDGEVVILSGYSEFEHARKAMQLNITDYLSKPASVDTIETVLKRVIN 121 Query: 125 VIRTEKEQSQETAEVEHRLNEGLPLIHERLLFSLL-----NGTYEPELMCYIGVPMDAPY 179 + ++ Q E+ +++ PL+ + SLL NG E + I D + Sbjct: 122 KLEEKQRQQGYLQELTNKVKRYEPLVETEWMKSLLTGRLRNGEIPEEFLAKITKWKDQQH 181 Query: 180 YQAVIGYTGSSNN-----TWNIEMESVRQSVSAALRSV--GNPVSLAYNE----RGFILL 228 + Y G N W + R SV +R V G P+ Y E R + L Sbjct: 182 IACSLTYDGPQNKELKPADWYL----FRYSVHKMIREVLNGYPIDFRYLEMDAYRSALCL 237 Query: 229 MSYRSTEEAAEAPLILE---RVSQELQRKRQIGLNFAQGKPCSEPYQIPQSFQEAREMLK 285 +S E + +++E +V Q + + G+ + + +SF EA Sbjct: 238 HVNKSVSEPVLSCMLMEIKDQVEQGIYSSFNVKTTVHYGRVKEDWTDLSESFHEA----- 292 Query: 286 HKLFSGNTEGQEGSHGLEDSFESG-RTMFPRKEKQRLLNAVYACNR-------EQVIGQL 337 E Q S L + +E G R FP + Q+L +A+ + E+ +G L Sbjct: 293 ------CMESQ--SFPLGNPYEDGTRATFPMESSQKLYDAIRYADATRAKEVLEEAVGVL 344 Query: 338 EDLQRQYSTAQHLYPAGYIRKLSAELIMLLSLILYERNESINQLIPGEPEFVTSIQSQND 397 ++ YST GY K+ E+ +++ LY+ I ++ + + + Q + Sbjct: 345 GEVP--YSTL-----VGY--KVGIEIWTIITYSLYDIGILIQEMFDEDFDLAQHLTKQGN 395 Query: 398 PKLVFDAVKRLYSLLLDLPVQSEMKKNRQTIRTVLDYINNHLDEEIRLEELAQKVFLTPN 457 + + + E K++Q I V+ YI HL E I L+++A +++++ N Sbjct: 396 WQEWIRFLCEQIEHICYHQQWDENIKHKQLIEQVMIYIEKHLAENITLQDIADELYISRN 455 Query: 458 YLGSLFKESVGIGFSDYLMKQRMELAKRLLLQPGSRIYEVSQKVGYKNPHYFSKLFKEYA 517 YLG +FK+ VG F +Y+ + RME AK+++ + IYEVS+KVGY NP YF+ +FK+Y Sbjct: 456 YLGQIFKKVVGESFKNYVTRLRMEKAKKMIQEGNFLIYEVSEKVGYVNPAYFTTMFKKYT 515 Query: 518 GIKP 521 G P Sbjct: 516 GYTP 519 >ref|NP_623880.1| AraC-type DNA-binding domain-containing proteins [Thermoanaerobacter tengcongensis] gb|AAM25484.1| AraC-type DNA-binding domain-containing proteins [Thermoanaerobacter tengcongensis] Length = 519 Score = 177 bits (450), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 152/533 (28%), Positives = 263/533 (49%), Gaps = 27/533 (5%) Query: 3 LHALLVDDEDFVLDGLKEAIDWKKYGINIAGAVNNGREALEFLEHSGITIDIVFTDIKMP 62 + + DDE V++G+ IDWK GI + G +G EAL + + DIV DI+MP Sbjct: 1 MKLFIADDEVEVVEGILTLIDWKGNGIELVGYAMDGEEAL--YKIKSLKPDIVLIDIRMP 58 Query: 63 VMDGFGLTEALKSAEYPCKIIVLTGHEEFEFAKKAIRYGIFDYLLKPVELESIELTIDRL 122 +DG + E + K I+L+G+++F FAKKAI F YLLKP E I + + Sbjct: 59 KLDGLEVIEKAQGEGIRFKSIILSGYDDFYFAKKAIELKSFSYLLKPCRPEEILKEVLKA 118 Query: 123 VKVIRTEKEQSQETAEVEHRLNEGLPLIHERLLFSLLNGTYEPELMC--YIGVPMDAPYY 180 + I E E+ E + N+ LP+I ER+L +L + ++ +D PY Sbjct: 119 REDIEKEIEKENTLKEFINYYNDTLPVIRERVLSEVLYRVRSSSEVAEDFVKYKIDFPYK 178 Query: 181 QAVIGYTGSSNNTWNIEMESVRQSVSAALRSVGNPVSL-AYNERGFILLMSYRSTEEAAE 239 + + N E+ + + + +R + + +R I ++ S EE + Sbjct: 179 KYCVVLMKIEIEAQNEIEEAYKLACADVIRKKAGDMKIEVIRDREEIAIL-INSEEEFKK 237 Query: 240 APL--ILERVSQELQRKRQIGLNFAQGKPCSEPYQIPQSFQEAREMLKHKLFSGNTEGQE 297 + L V E+ K ++ F GK +I S+ +A+E L+ K F+ + Sbjct: 238 ESIEGFLNDVKSEIYDKLEVRAYFGIGKWVEGADKIKYSYYQAKEALELKFFAEEFD--- 294 Query: 298 GSHGLEDSFESGRTMF-PRKEKQRLLNAVYACNREQVIGQLEDLQRQYSTAQHLYPAGYI 356 + ED + ++ P E++ ++N+V RE + ++E+ LY G+ Sbjct: 295 -AIFYEDIWPHQDNLYYPVNEEREIINSVILNKREDLNKKVENF------LNALYTGGFN 347 Query: 357 RKL--SAELIMLLSLI--LYERNESINQLIPGEPEFVTSIQSQNDPKLVFDAVKRLYSLL 412 + ++ L++L +LI YE+N I I GE F +++ L ++ +Y + Sbjct: 348 QWFVKASILVLLGNLIKACYEKNVDIGD-IAGEKAFEGILKADRKETLKSLSLSVIYKIA 406 Query: 413 LDLPVQSEMKKNRQTIRTVLDYINNHLDEEIRLEELAQKVFLTPNYLGSLFKESVGIGFS 472 ++ KN I+ ++YI+ + D++I LE +A++V++TP YL LFK+ + I F Sbjct: 407 E--KIERAGDKN-PIIKDAVEYIDKNYDKDISLESVAKEVYVTPAYLSILFKKEMNINFV 463 Query: 473 DYLMKQRMELAKRLLLQPGSRIYEVSQKVGYKNPHYFSKLFKEYAGIKPSQYK 525 YL K R+E AK+LL + Y+V+ VG+ + YFS++FK+Y G+ PSQY+ Sbjct: 464 SYLHKVRVEKAKKLLEDRSLKTYQVANMVGFGDEKYFSQVFKKYTGLTPSQYR 516 >ref|NP_563003.1| two-component response regulator [Clostridium perfringens] dbj|BAB81793.1| two-component response regulator [Clostridium perfringens str. 13] Length = 507 Score = 165 bits (418), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 140/523 (26%), Positives = 251/523 (47%), Gaps = 32/523 (6%) Query: 5 ALLVDDEDFVLDGLKEAIDWKKYGINIAGAVNNGREALEFLEHSGITIDIVFTDIKMPVM 64 +L DDE+ +L GL+ I+W++ G+ I +NG+EA++ + + +DIV TDI MP + Sbjct: 4 VMLADDENLILQGLENIIEWEELGLEIVNKASNGQEAIDKFKEN--PVDIVVTDINMPQV 61 Query: 65 DGFGLTEALKSAEYPCKIIVLTGHEEFEFAKKAIRYGIFDYLLKPVELESIELTIDRLVK 124 G L + LK K I+L+G+++F +AKKAI G+ +Y+LKP++ E +E T+ + Sbjct: 62 TGLELLKELKKINSDVKFIILSGYDDFSYAKKAIELGVENYILKPIDEEELEKTLKNTIN 121 Query: 125 VIRTEKEQSQETAEVEHRLNEGLPLIHERLLFSLLNGTYEPELMCYIGVPMDAPYYQAVI 184 I+ EKE+++ + + L + LI +L + E M +++ Y I Sbjct: 122 KIKQEKEENKSSLGKHNIL---IKLIKGKLAQGEIEENKEGFYM-----NLNSERYSLCI 173 Query: 185 GYTGSSNNTWNIEMESVRQSVSAALRSVGNPVSLAYN-ERGFILLMSYRSTEEAAEAPLI 243 T S ++ E + V+ + N + Y + IL+ S+ E Sbjct: 174 INTRSRYDS----EEMLHNIVNVIKENTQNNFEIIYTLDEELILINSWDEALSKKEIKKY 229 Query: 244 LERVSQELQRKRQIGLNFAQGKPCSEPYQIPQSFQEAREMLKHKLFSGNTEGQEGSHGLE 303 +++ +++ + I + + G+P + Y+I S++EA + K+ L T G E Sbjct: 230 YDKLKEQIINEYGIDVFLSVGEPVCDLYKISSSYKEANNLKKYVL----TLGYNKCITTE 285 Query: 304 DSFESGRTMFPRKEKQRLLNAVYACNREQVIGQLEDLQRQYSTAQHLYPAGYIRKLSAEL 363 D + E LN + I E + + + L P I LS ++ Sbjct: 286 DVKDINEKNINFSEVLDKLNKRIIA---KDIEGAEKIIEETVEDKKLNPRN-IYDLSVKI 341 Query: 364 IMLLSLILYE---RNESINQLIPGEPEFVTSIQSQNDPK-LVFDAVKRLYSLLLDLPVQS 419 + LL I+ E + + E + S ++ D K L+ ++ + L+ + Sbjct: 342 LFLLDGIVEEFKVEKQYTGNSLGEEIVALCSEDTREDIKTLLCSEIREVIELMHPTTI-- 399 Query: 420 EMKKNRQTIRTVLDYINNHLDEEIRLEELAQKVFLTPNYLGSLFKESVGIGFSDYLMKQR 479 K I+ ++ Y+N + EE+ L+ LAQK + +YLG +F + VG FS+YL K + Sbjct: 400 ---KYSPVIQQIISYVNENYYEEVSLKTLAQKYHINTSYLGQVFTKEVGCSFSEYLNKTK 456 Query: 480 MELAKRLLLQPGSRIYEVSQKVGYKNPHYFSKLFKEYAGIKPS 522 AK L+L +I ++++KVGY + YF + FK+Y G+ PS Sbjct: 457 NMKAKELILNTNMKINDIAKKVGYLDTSYFYRKFKKYYGVCPS 499 >ref|NP_242975.1| BH2109~unknown conserved protein [Bacillus halodurans] pir||E83913 hypothetical protein BH2109 [imported] - Bacillus halodurans (strain C-125) dbj|BAB05828.1| BH2109~unknown conserved protein [Bacillus halodurans] Length = 525 Score = 164 bits (415), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 133/547 (24%), Positives = 266/547 (48%), Gaps = 56/547 (10%) Query: 5 ALLVDDEDFVLDGLKEAIDWKKYGINIAGAVNNGREALEFLEHSGITIDIVFTDIKMPVM 64 LL DDE FV GLK I+W+K G +A +NG +A + ++ I D+V TDI+MPV Sbjct: 4 VLLADDEFFVRHGLKSLIEWEKCGYEVAAEADNGEDAFKLVQE--IKPDLVITDIRMPVF 61 Query: 65 DGFGLTEAL-KSAEYPCKIIVLTGHEEFEFAKKAIRYGIFDYLLKPVELESIELTIDRLV 123 DG L + + ++ + K I+++G+ +F +A+KA+R+G D++LKP++ + +E + +L Sbjct: 62 DGLQLIQKVNETLSFNTKFIIISGYNDFSYAQKAVRFGAVDFVLKPIDQDELEAALIKLA 121 Query: 124 KVIRTEKEQSQETAEVEHRLNEGLPLIHERLLFSLLNGTYEPELMCY---IGVPMDAPYY 180 + EK + + +V L+ + + SL E E+ + + + YY Sbjct: 122 ATLDQEKATNSDQEKV---------LLDQIFIHSLGENKKENEVRRWAAKLNINNRHFYY 172 Query: 181 QAVIGYTGSS------NNTWN------IEMESVRQSVSAALRSVGNPVSLAYNERGFILL 228 ++ S N + I RQ+ + ++ + AY G ++ Sbjct: 173 YLLLEVNNLSLDKGFINEQYKEPIRKVIRETVARQAATEEYTAIYEQLDHAY---GLLIT 229 Query: 229 MSYRSTEEAAEAPLILERVSQELQRKRQIGLNFAQGKPCSEPYQIPQSFQEAREMLKHK- 287 + PL E++ +++Q I L G + I +S++ A + +K Sbjct: 230 SEHLKKFNGQIEPLA-EKLRKDIQDFTNIPLTVYVGAKTDDLSTIKKSYETANSLRNYKY 288 Query: 288 LFS-GNTEGQEGSHGLEDSF-ESGRTMFPRKEKQRLLNAVYACNREQVIGQLEDLQRQYS 345 +F+ N E + ++ ++ E +F L+ + N ++++ ++ + ++ Sbjct: 289 IFNEKNVFIHEQTESVDTTYDELNNHLFVT-----LMEQMEENNSDRIVNIIDKIFSEFQ 343 Query: 346 TAQHLYPAGYIRKLSAELIMLLSLILYERNESINQLIPGEPEFVTSIQSQNDPK---LVF 402 T + + P+ ++ + ++ + Q + G+ + S Q+ + + L F Sbjct: 344 TKKFV-PSAVKTSVNRCVHKVMQTV---------QAMEGDTGKIISAQAMTNWESYNLTF 393 Query: 403 DAVKRLYSLLL---DLPVQSEMKKNRQT-IRTVLDYINNHLDEEIRLEELAQKVFLTPNY 458 D +K++++ + + +Q K+N ++ I V YI NH E I L+ +A ++ P Y Sbjct: 394 DQLKQVFTKFVLEAAVIIQELRKENMKSDIYKVKTYIENHYHENISLKSIASLFYMNPVY 453 Query: 459 LGSLFKESVGIGFSDYLMKQRMELAKRLLLQPGSRIYEVSQKVGYKNPHYFSKLFKEYAG 518 +G LFK++ G+ F +YL+K RM AK+LL Q R+YEV+++VG+ + YF F++ Sbjct: 454 MGQLFKKTFGVYFKEYLLKLRMNEAKKLLRQTDMRVYEVAERVGFGSTDYFVTQFEKINK 513 Query: 519 IKPSQYK 525 + P++Y+ Sbjct: 514 MTPTEYR 520 >ref|NP_621980.1| CheY-like receiver domains [Thermoanaerobacter tengcongensis] gb|AAM23584.1| CheY-like receiver domains [Thermoanaerobacter tengcongensis] Length = 529 Score = 161 bits (407), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 154/546 (28%), Positives = 260/546 (47%), Gaps = 50/546 (9%) Query: 6 LLVDDEDFVLDGLKEAIDWKKYGINIAGAVNNGREALEFLEHSGITIDIVFTDIKMPVMD 65 L+ DDE VLD +K I+ I G +GREA+E + + D++F DI+MP +D Sbjct: 5 LIADDEQIVLDSIKFIIEKNNVQAEIVGTAKSGREAIE--KADLLKPDLIFMDIRMPGID 62 Query: 66 GFGLTEALKSAEYPCKIIVLTGHEEFEFAKKAIRYGIFDYLLKPVELESIELTIDRLVKV 125 G +K +++T +E F +AK+AI G+ DYLLKP+ I I++ KV Sbjct: 63 GIEAIRQIKERHKEMIFVIITAYEYFNYAKEAIDLGVMDYLLKPLNKNKIIEVIEKASKV 122 Query: 126 IRTEKEQSQETAEVEHRLNEGLPLIHERLLFSLLNGTYEPELMCY----IGVPMDAPYYQ 181 I ++ E+ ++N+ +P + E+ L+++L G Y + + + ++ Y Sbjct: 123 IEERRKAVLTEIELREKINKIMPYLEEQFLYTVLFGGYVGGSLDFYEEIFDMKLEKGYIM 182 Query: 182 AVIGYTGSSN-NTWNIEMESVRQSVSAALRSVGNPVSLAYNERGFI-LLMSYRSTEEAA- 238 + + +SN +IE+ RQS+ LR VS F+ + Y EE Sbjct: 183 IFLMRSDTSNEREKSIEVNLKRQSLYEHLRIFLKGVSKCILGPFFMDKICVYFPVEEKTP 242 Query: 239 -----EAPLILERVSQELQRKRQIGLNFAQGKPCSEPYQIPQSFQEAREMLKHKLFSGNT 293 + I +V + LQ + L G+ S I +S+ EA L KLF +T Sbjct: 243 FEVKNSSVKIANKVLESLQGSEKENLRVGIGREYSFN-NIVKSYYEAEMAL--KLFPDDT 299 Query: 294 EGQEGSHGLEDSFESGRTMFPRKEKQRLLNAVYACNREQV-IGQLE--DLQRQYSTAQHL 350 H + S + FP Y ++E++ I +L DL R + + Sbjct: 300 ----IVHFDDAVGTSTISHFP-----------YPLDKEKLFIERLVEGDLARAFKVFDEI 344 Query: 351 Y---------PAGYIRKLSAELIMLL--SLILYERNESINQLIPGEPEFVTSIQSQNDPK 399 Y AG I+ EL+ ++ S Y S + I + E + I+ + K Sbjct: 345 YEWMILEYDKDAGKIKSKLIELVGIIRRSFYYYLEEGSFKEEI-AQIEELLKIEDLRELK 403 Query: 400 LVFDAVKRLYSLLLDLPVQSEMKKNRQTIRTVLDYINNHLDEEIRLEELAQKVFLTPNYL 459 LVF +K L ++ ++ V ++ K + T++ V++++ + ++I LE+ A++V ++ +Y Sbjct: 404 LVF--IKMLKDIVENIRVVNKKKWDNITMK-VINFLEENFSKDISLEDAAREVNMSYHYF 460 Query: 460 GSLFKESVGIGFSDYLMKQRMELAKRLLLQPGSRIYEVSQKVGYKNPHYFSKLFKEYAGI 519 FKE VG F DYL R+ AK LL + EVS KVGY +P+YFSK+FK+ G+ Sbjct: 461 SKFFKEQVGENFVDYLTNLRIRKAKELLKNSSLSVKEVSYKVGYSDPNYFSKIFKKVTGV 520 Query: 520 KPSQYK 525 P+++K Sbjct: 521 TPTEFK 526 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.318 0.136 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 745,284,626 Number of extensions: 30711291 Number of successful extensions: 98723 Number of sequences better than 1.0e-05: 1241 Number of HSP's gapped: 100567 Number of HSP's successfully gapped: 1292 Length of query: 525 Length of database: 757,237,578 Length adjustment: 130 Effective length of query: 395 Effective length of database: 404,274,708 Effective search space: 159688509660 Effective search space used: 159688509660 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 128 (53.9 bits)