BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0447.0005.p (450 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_242748.1| cytosine permease [Bacillus halodurans] >gi|254... 190 8e-47 ref|NP_343087.1| Cytosine permease (codB) [Sulfolobus solfataric... 165 2e-39 ref|NP_463985.1| similar to permeases [Listeria monocytogenes EG... 162 1e-38 ref|NP_469817.1| similar to permeases [Listeria innocua] >gi|255... 160 6e-38 ref|NP_987909.1| Permease for cytosine/purines, uracil, thiamine... 155 1e-36 >ref|NP_242748.1| cytosine permease [Bacillus halodurans] pir||B83885 cytosine permease BH1882 [imported] - Bacillus halodurans (strain C-125) dbj|BAB05601.1| cytosine permease [Bacillus halodurans] Length = 445 Score = 190 bits (482), Expect = 8e-47, Method: Compositional matrix adjust. Identities = 134/379 (35%), Positives = 211/379 (55%), Gaps = 18/379 (4%) Query: 10 GRQGNIAALEDYAIQSVPAEKRKSWLNVAFTSCGWIISLSTIFVGGSLAAGMTFGQAILA 69 +Q ++D+ VP E RK W++++ G I+LS +GG+L G+T GQAILA Sbjct: 2 NKQSEARKIDDFERMPVPEEHRKGWIHLSLVWLGIAIALSATVLGGTLGGGLTLGQAILA 61 Query: 70 AVIGMTILAVYGFFQGWMGAKYGVATAVLARQAFGRAGAGLFGILLSLTMGIGWFGWQVA 129 ++G +L++ +GA+ G++T ++++ A G GA + ++++ + GWFG Q+ Sbjct: 62 TMLGALVLSIVSACCSVVGARTGLSTGLVSKFALGTYGAYVVSAVIAIAL-FGWFGVQLD 120 Query: 130 FFGSTIEQMFPGQWFAD--PTFAIIWGGVLMIFTALIGYKGITYLSFVAVP---LVIVLS 184 FG++ +Q+ + + +I GG+LM TA+IGYK I LS AVP L+++ S Sbjct: 121 LFGTSFQQVIMNVFGLNIPKILLVIIGGILMTSTAVIGYKAIEKLSKAAVPLMGLLLIAS 180 Query: 185 IWGIFVAADASGGLSNLFALQPTGASLGLFAGITLVVGNAALGAIVFPDVSRYGKTPLAG 244 +W + +S S++ TG L L I+LV+G+ A+GA++ PD++RY KTP Sbjct: 181 LWRVL----SSQQWSDVVNAPMTGDPLPLGIAISLVIGSFAVGAVIGPDIARYAKTPKDA 236 Query: 245 GMGAAVGYFVGGIFSVVAGAAMTFAAQLPDLGATPNIPAVMAKLGMGFFAFLILVFAQWS 304 +G+ G+ VG FS A + AA L +I A+M LG G FA LIL+ AQW+ Sbjct: 237 VIGSFSGFLVG--FS----AVLIVAAILAKATGEVDIVAIMLGLGWGTFAMLILILAQWT 290 Query: 305 NNDNNLYTGALGLRNVVK-LPKFXXXXXXXXXXXXXXXTGYQDHFVPFLNFLGVYVPPIA 363 NDNNLY+ ALG + K +PK G D+F+PFL FL +PPI Sbjct: 291 TNDNNLYSAALGFSVIFKSIPKAKLTIGAGIIGTLMAVFGIYDNFIPFLIFLSALIPPIG 350 Query: 364 GVMIADHWIVRRGTYQFGE 382 G+ +AD+ ++ +G Y F Sbjct: 351 GIYVADY-LLNKGKYSFAN 368 >ref|NP_343087.1| Cytosine permease (codB) [Sulfolobus solfataricus] pir||F90327 cytosine permease (codB) [imported] - Sulfolobus solfataricus gb|AAK41877.1| Cytosine permease (codB) [Sulfolobus solfataricus] Length = 453 Score = 165 bits (418), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 124/429 (28%), Positives = 201/429 (46%), Gaps = 23/429 (5%) Query: 10 GRQGNIAALEDYAIQSVPAEKRKSWLNVAFTSCGWIISLSTIFVGGSLAAGMTFGQAILA 69 G++ + +DY+++ VP + R + NV +++ I+ GG+L G+TF QAI+A Sbjct: 3 GKEEISSKYDDYSLKEVPKDSRYGFFNVFLVFSSVYGAIAVIWAGGALGYGLTFSQAIIA 62 Query: 70 AVIGMTILAVYGFFQGWMGAKYGVATAVLARQAFGRAGAGLFGILL-SLTMGIGWFGWQV 128 + G +L + G +GA G++T V+ R GR G + G+LL ++T GIGW+ + Sbjct: 63 VLSGTVVLGILGSLTAAVGAYSGLSTYVMWRHPLGRWGGKIAGLLLITITTGIGWYAVET 122 Query: 129 AFFGSTIEQMFPGQWFADPTFAIIWGGVLMIFTALIGYKGITYLSFVAVPLVIVLSIWGI 188 FG + ++FP F A IWGG+LM +GY+ +++LS+ +P I L GI Sbjct: 123 WLFGIVMSEIFPNNPFFSVGVAAIWGGILMTIMTYVGYRMLSFLSYFTIPFHIWLIAIGI 182 Query: 189 FVAADASGGLSNLFALQPTGASLGLFAGITLVVGNAALGAIVFPDVSRYGKTPLAGGMGA 248 + GG + A PT + + L GI+ +G + G I+ PD+SR+ K+ G Sbjct: 183 AIVLALKGGFHTVMAAVPT-SHMSLLDGISATIGLYSAGTIISPDISRFAKSAKDAGYAW 241 Query: 249 AVGYFVGGIFSVVAGAAMTFAAQLPDLGATPNIPAVMAKLGMGFFAFLILVFAQWSNNDN 308 F ++ G A+ A + I M +LGMG LI+VF Q+ N + Sbjct: 242 FAHIIFLYPFLILGGVAIVLAT------GSYLITNAMLELGMGVGVLLIIVFGQFIINTD 295 Query: 309 NLYTGALGLRNVVKLPK-FXXXXXXXXXXXXXXXTGYQ--DHFVPFLNF---LGVYVPPI 362 NLY+G+L L N++ + + G+ PF NF LG ++P + Sbjct: 296 NLYSGSLSLVNLIPMRREIASVINGVIGTAIAAYVGFSAGSSITPFENFISLLGDFLPAM 355 Query: 363 AGVMIADHWIVRR---------GTYQFGEGTKYSXXXXXXXXXXXXXXXXXXXXXWGISP 413 G+++AD +IV++ Y+F KY GI Sbjct: 356 GGIVLADFYIVKKYVNKIQDPHKRYEFVPNNKYYNINIAGILALALGSIIGYFVNAGIPA 415 Query: 414 INSTVLGLI 422 INS V G + Sbjct: 416 INSLVTGFL 424 >ref|NP_463985.1| similar to permeases [Listeria monocytogenes EGD-e] pir||AI1131 permeases homolog lmo0456 [imported] - Listeria monocytogenes (strain EGD-e) emb|CAC98535.1| lmo0456 [Listeria monocytogenes] Length = 427 Score = 162 bits (411), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 108/354 (30%), Positives = 188/354 (53%), Gaps = 16/354 (4%) Query: 29 EKRKSWLNVAFTSCGWIISLSTIFVGGSLAAGMTFGQAILAAVIGMTILAVYGFFQGWMG 88 E+ +SW ++AF G +I + ++ VGG+L +GM +AIL A++G ++ V+ +QG Sbjct: 8 EQAQSWQSLAFVWTGAMICVPSLLVGGTLISGMPLWEAILIALLGYGVIVVFMIYQGMQS 67 Query: 89 AKYGVATAVLARQAFGRAGA-GLFGILLSLTMGIGWFGWQVAFFGSTIEQMFP--GQWFA 145 + G+ +A Q FG G+ + ILL++ +GWFG Q G+ Q G Sbjct: 68 SDLGIPAVSVASQVFGEQGSKKIISILLAIAC-LGWFGIQANVCGAAFSQFLGIYGINLP 126 Query: 146 DPTFAIIWGGVLMIFTALIGYKGITYLSFVAVPLVIVLSIWGIFVAADASGGLSNLFALQ 205 P ++IW GV+M+ +A+ G + ++ L+++AVP+++ + I+G+ V+ + +GGL+ + + Sbjct: 127 VPVSSLIW-GVIMLLSAIYGIRILSILNYIAVPILLFVCIYGLVVSLN-NGGLAVVENYK 184 Query: 206 PTGASLGLFAGITLVVGNAALGAIVFPDVSRYGKTPLAGGMGAAVGYFVGGIFSVVAGAA 265 P G S+ G+ + +G+ ALGA++ D S+Y K+ A VG G+ + GA Sbjct: 185 PAG-SMSFMTGLAITIGSFALGAVIAGDYSQYTKSRKDVVKAAIVGILPSGVLMIAVGAI 243 Query: 266 MTFAAQLPDLGATPNIPAVMAKLGMGFFAFLILVFAQWSNNDNNLYTGALGLRNVVKLPK 325 + A T +I V LG+ + L+ A W+ N N ++G + + NV + + Sbjct: 244 LALTA------GTADISVVFTNLGLPVLGIIGLILAAWTTNAVNAFSGGIAIINVFNISE 297 Query: 326 FXXXXXXXXX---XXXXXXTGYQDHFVPFLNFLGVYVPPIAGVMIADHWIVRRG 376 G +HFVP ++ L VPP+AGVMIA +WIV++G Sbjct: 298 KYHKVAVAIAGGLGTVLAVIGILNHFVPIMSVLSAMVPPVAGVMIASYWIVQKG 351 >ref|NP_469817.1| similar to permeases [Listeria innocua] pir||AI1491 permeases homolog lin0473 [imported] - Listeria innocua (strain Clip11262) emb|CAC95705.1| lin0473 [Listeria innocua] Length = 427 Score = 160 bits (405), Expect = 6e-38, Method: Compositional matrix adjust. Identities = 106/354 (29%), Positives = 188/354 (53%), Gaps = 16/354 (4%) Query: 29 EKRKSWLNVAFTSCGWIISLSTIFVGGSLAAGMTFGQAILAAVIGMTILAVYGFFQGWMG 88 E+ +SW ++AF G +I + ++ VGG+L +GM +AIL A++G ++ ++ +QG Sbjct: 8 EQTQSWQSLAFVWTGAMICVPSLLVGGTLISGMPLWEAILIALLGYGVIVLFMIYQGMQS 67 Query: 89 AKYGVATAVLARQAFGRAGA-GLFGILLSLTMGIGWFGWQVAFFGSTIEQMFP--GQWFA 145 + G+ +A Q FG G+ + ILL++ +GWFG Q G+ Q G Sbjct: 68 SDLGIPAVSVASQVFGEQGSKKIISILLAIAC-LGWFGIQANVCGAAFSQFLGIYGINLP 126 Query: 146 DPTFAIIWGGVLMIFTALIGYKGITYLSFVAVPLVIVLSIWGIFVAADASGGLSNLFALQ 205 P ++IW GV+M+ +A+ G + ++ L++VAVP+++ + I+G+ V+ + +GG++ + + Sbjct: 127 VPISSLIW-GVIMLLSAIYGIRILSILNYVAVPILLFVCIYGLIVSLN-NGGIAVVENYK 184 Query: 206 PTGASLGLFAGITLVVGNAALGAIVFPDVSRYGKTPLAGGMGAAVGYFVGGIFSVVAGAA 265 P +S+ G+ + +G+ ALGA++ D S+Y K+ A VG G+ + GA Sbjct: 185 P-ASSMSFMTGLAITIGSFALGAVIAGDYSQYTKSRKDVVKAAIVGILPSGVLMIAVGAV 243 Query: 266 MTFAAQLPDLGATPNIPAVMAKLGMGFFAFLILVFAQWSNNDNNLYTGALGLRNVVKLPK 325 + A T +I V LG+ + L+ A W+ N N ++G + + NV + + Sbjct: 244 LALTA------GTADISVVFTNLGLPVLGIIGLILAAWTTNAVNAFSGGIAIINVFNISE 297 Query: 326 FXXXXXXXXX---XXXXXXTGYQDHFVPFLNFLGVYVPPIAGVMIADHWIVRRG 376 G +HFVP ++ L VPP+AGVMIA +WIV++G Sbjct: 298 KYHKVAVAIAGGLGTILAVIGILNHFVPIMSVLSAMVPPVAGVMIASYWIVQKG 351 >ref|NP_987909.1| Permease for cytosine/purines, uracil, thiamine, allantoin [Methanococcus maripaludis S2] emb|CAF30345.1| Permease for cytosine/purines, uracil, thiamine, allantoin [Methanococcus maripaludis] Length = 411 Score = 155 bits (393), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 128/418 (30%), Positives = 209/418 (50%), Gaps = 18/418 (4%) Query: 17 ALEDYAIQSVPAEKRKSWLNVAFTSCGWIISLSTIFVGGSLAAGMTFGQAILAAVIGMTI 76 A +DYA+++VP+E +K +L + G+ ++++ GG++ G+ F +LA ++G + Sbjct: 7 ADQDYALETVPSESKKGFLPMFAIMLGFTFFSASMWAGGTIGTGLKFQTFLLAVLMGNLL 66 Query: 77 LAVYGFFQGWMGAKYGVATAVLARQAFGRAGAGLFGILLSLTMGIGWFGWQVAFFGSTIE 136 L +Y ++G+ G++T +LAR +FG G+ L +L++T +GWFG VA F Sbjct: 67 LGLYTGALAYIGSSTGLSTHLLARYSFGEKGSYLASFILAITQ-VGWFGVGVAMFS---- 121 Query: 137 QMFPGQWFA--DPTFAIIWGGVLMIFTALIGYKGITYLSFVAVPLVIVLSIWGIFVAADA 194 P + D ++ G+LM TA G K +T LS ++VP + +L I+ + A ++ Sbjct: 122 --LPVHYATGIDLNILLLLSGILMTTTAYFGIKSLTVLSMISVPAITLLGIYSVTGAVNS 179 Query: 195 SGGLSNLFALQPTGASLGLFAGITLVVGNAALGAIVFPDVSRYGKTPLAGGMGAAVGYFV 254 GG+S LFA++P +LGL G++L +G+ G + PD SR+ K+ G + + +F+ Sbjct: 180 IGGISELFAIEPAN-NLGLAVGLSLCIGSFISGGTLTPDFSRFSKSKSIGVISTFIAFFI 238 Query: 255 GGIFSVVAGAAMTFAAQLPDLGATPNIPAVMAKLGMGFFAFLILVFAQWSNNDNNLYTGA 314 G + GA LG + +I VM K G+ A +IL W+ NDN LY Sbjct: 239 GNSLMFIFGAVGA-----STLGQS-DISEVMLKQGLIIPAIIILGLNIWTTNDNALYASG 292 Query: 315 LGLRNVVKLPKFXXXXXXXXXXXXXXXTGYQDHFVPFLNFLGVYVPPIAGVMIADHWIVR 374 LG N+ K+PK Y ++FV +L L +P I G++I+D++I + Sbjct: 293 LGFSNITKIPKKHVVIFNGLIGTLGALVLY-NNFVGWLTLLSSIIPSIGGIIISDYFINK 351 Query: 375 RGTYQFGEGTKYSXXXXXXXXXXXXXXXXXXXXXWGISPINSTVLGLIIYPVLTALLR 432 R Y E K GISPIN+ IIY VL L + Sbjct: 352 RQKYASLENIKVKKVHWNAVIAWVLGVFASQFLP-GISPINAVFGSAIIYIVLETLKK 408 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.326 0.142 0.448 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 621,170,562 Number of extensions: 24734969 Number of successful extensions: 104942 Number of sequences better than 1.0e-05: 78 Number of HSP's gapped: 104824 Number of HSP's successfully gapped: 78 Length of query: 450 Length of database: 757,237,578 Length adjustment: 129 Effective length of query: 321 Effective length of database: 406,989,807 Effective search space: 130643728047 Effective search space used: 130643728047 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 128 (53.9 bits)