BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0443.0014.p (569 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongen... 206 1e-51 ref|NP_782429.1| two-component sensor kinase yesM [Clostridium t... 186 1e-45 ref|NP_242976.1| BH2110~unknown conserved protein [Bacillus halo... 165 3e-39 ref|NP_561490.1| two-component sensor histidine kinase [Clostrid... 164 8e-39 ref|NP_244314.1| two-component sensor histidine kinase [Bacillus... 160 9e-38 >ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongensis] gb|AAM25485.1| predicted ATPase [Thermoanaerobacter tengcongensis] Length = 593 Score = 206 bits (524), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 147/454 (32%), Positives = 230/454 (50%), Gaps = 40/454 (8%) Query: 146 IKEASWYPHVM-KSVDVLWFS------------SGRSVYSARRILSTKQENPKDNILFAL 192 IK S+Y V+ K+ +W S + + AR +L P + +L Sbjct: 141 IKRTSFYREVLEKNGAPMWLSLENLPFDLIIKNNYPKIAMARVLLDFNTYKP-EGLLVIC 199 Query: 193 VDYDALFKTF-EPLESHGAEIVITDSNGN-----SIYSSGADRTNSGIP---ISDKEADE 243 ++ + K + E L+ + I D NGN S +S ++ I + DK+ Sbjct: 200 INIPTIEKVYSENLKEKESAFFIADRNGNIISFKSTFSGFTPKSAQNILAKYLKDKQNVV 259 Query: 244 LHWSGKNYTVLQSSIPITGWK----VYLYKPTSLITKSAWWIALTVLLMXXXXXXXXXXX 299 ++ + V S IP + W+ V L + I S L +L+ Sbjct: 260 ININSSKLLVTSSPIPTSDWRLVSVVSLKNAINSIRISFIEFYLRILVFCLLFAFLV--- 316 Query: 300 GTLFSRKIMLPIHRLHKNMKLIGEGNLEIKVFSD--SKDEIGDLIRGFGSMLGRTKTLID 357 FSR + P+ RL +MK + +GNLE KV + SKDEI +I+ + M+ R LI+ Sbjct: 317 SMYFSRALTHPLERLANSMKKVRQGNLEEKVEFEYHSKDEIAIVIKEYNRMVERINDLIN 376 Query: 358 TVYVGEIARKEYEMKALQAQINPHFLYNSLSLINWRAIRIHATDISEMAQLLSTFYRTTL 417 + EI ++E E+KAL+AQINPHFLYN+L I W+A + ++SEM LS +R TL Sbjct: 377 RILKLEINKREAELKALEAQINPHFLYNTLDTIFWKAEKAKDRELSEMIYSLSRLFRLTL 436 Query: 418 NKGENLISVSDEILNVQSYINIQLIMHSNSFEIDYQIDDSILSCRMPNLMLQPLIENAII 477 N+GE I V E ++ Y+ +Q + N F+ +I D IL +P L+LQP +ENAI+ Sbjct: 437 NRGEEFIQVRGEKELIERYLFLQSKRYKNKFKYSVKISDEILDYYIPKLILQPFVENAIV 496 Query: 478 HGIENREDGGGIIHLSGKKEDQSIVFLITDNGIGVEQERLALLLK-------SQSKGYGL 530 HG+EN + + + G+KE +++ F+I DNG G+ +E L L + + GY + Sbjct: 497 HGLENNSE-ESFVEVIGEKEGENLKFIIKDNGPGMSEETLEKLKRFIESENIEEKVGYAI 555 Query: 531 KNVNDRAVVMYGEQYGLTINSIPGEGTQVLLKIP 564 +NVN+R + YG++Y L I S GEGT + L +P Sbjct: 556 RNVNERLRLYYGDKYELKIESRQGEGTTISLILP 589 >ref|NP_782429.1| two-component sensor kinase yesM [Clostridium tetani E88] gb|AAO36366.1| two-component sensor kinase yesM [Clostridium tetani E88] Length = 577 Score = 186 bits (472), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 112/322 (34%), Positives = 179/322 (55%), Gaps = 7/322 (2%) Query: 249 KNYTVLQSSIPIT-GWKVYLYKPTSLITKSAWWIALTVLLMXXXXXXXXXXXGTLFSRKI 307 K+ TV SS+P T W + + I I +L + + S I Sbjct: 247 KDSTVFFSSVPYTENWILCIIVENKKIHTQINQIINLILFVGLILLLAAILLSIVISGSI 306 Query: 308 MLPIHRLHKNMKLIGEGNLEIKVFSDSKDEIGDLIRGFGSMLGRTKTLIDTVYVGEIARK 367 + PIHRL NM I +GN + + DEI L + F ML K LI+ VY E ++ Sbjct: 307 VKPIHRLKSNMLEISKGNFDSYYEIKNNDEISILGQVFNQMLTDIKRLINKVYQVEKQKR 366 Query: 368 EYEMKALQAQINPHFLYNSLSLINWRAIRIHATDISEMAQLLSTFYRTTLNKGENLISVS 427 E++ LQ+QINPHFLYN+L I W+A+ +A ++ +M LS F+R +L+ G+ I++S Sbjct: 367 SAELRVLQSQINPHFLYNTLDTIQWKALEYNAFEVVDMINYLSNFFRISLSDGKEFITIS 426 Query: 428 DEILNVQSYINIQLIMHSNSFEIDYQIDDSILSCRMPNLMLQPLIENAIIHGIENREDGG 487 DE+ +V +Y+ IQ I + + +D S+ +P L++QPL+EN+I HG++ + Sbjct: 427 DEVAHVSNYLEIQKIRYKDKISYSMDVDSSLDQYLIPKLIVQPLVENSIYHGLK-LQKHK 485 Query: 488 GIIHLSGKKEDQSIVFLITDNGIGVEQERLALLLKS-----QSKGYGLKNVNDRAVVMYG 542 GII++S +D + + DNG+G++ E+L L K+ ++ YGL N+N+R + +G Sbjct: 486 GIINVSISSKDGFLFIKVIDNGLGMDVEQLRTLRKNLWESIETNHYGLYNINERLKLAFG 545 Query: 543 EQYGLTINSIPGEGTQVLLKIP 564 ++Y + I S GTQVLL+IP Sbjct: 546 KKYSIEIKSELKIGTQVLLRIP 567 >ref|NP_242976.1| BH2110~unknown conserved protein [Bacillus halodurans] pir||F83913 hypothetical protein BH2110 [imported] - Bacillus halodurans (strain C-125) dbj|BAB05829.1| BH2110~unknown conserved protein [Bacillus halodurans] Length = 585 Score = 165 bits (417), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 144/599 (24%), Positives = 276/599 (46%), Gaps = 58/599 (9%) Query: 8 KQKIGDFRFQTKIKLSFLLVSMIPVIVLGSFCFSETRSLLVQQSKADLNATLQQSVLAVN 67 K + + + + K+ L ++ +P+++ ++ T + + Q D+ + Q N Sbjct: 5 KYSLNNVKLRNKLLLLYIFCVFLPILLTNIIFYNVTANNIKAQKMDDIELVVDQITNEFN 64 Query: 68 NQLDVYNKVMNFLSFNQEIVNAANTTYTSAY---EMYDQLNNVIDQNFFTARY-----LN 119 N +D + + N I + T Y +A E YD F+ Y L Sbjct: 65 NAVDQAIGISSGFYTNTRIYDFFETEYETAIDYIEAYD---------FYLREYSRFSPLY 115 Query: 120 TGVKQIILYTGTNLPPHGNTVRPIDE-IKEASWYPHVMKSVDVLWF----SSGRSVYSAR 174 ++ I YT + +RP+ E KE WY + ++ + ++ ++S Sbjct: 116 YSIQSISFYTDNPSFIYAGGIRPLTEHTKEEKWYRLLTEANHPIIIRTNPATDSGLFSVI 175 Query: 175 RILSTKQENPKDNILFALVDYDALFKTFEPLESHGA---EIVITDSNGNSIYSSGADRTN 231 R L +N ++ +D + L T + + ++ A E+ + + N +SS + Sbjct: 176 RELDY-HKNKYNHKKIVRIDLNPL--TIKQIFNNAAFTGEVYLLNGERNIEFSSNEE--- 229 Query: 232 SGIPISDKEADELHWSGKNY--------TVLQSSIPITGWKVYLYKPTSLITKSAWWIAL 283 + ++LH+ + + S + GW+V + I + + Sbjct: 230 -----VNWRTEQLHFDALEFPEDTIFTKERMLSQNYLEGWRVAGTISENEILEELYKSRE 284 Query: 284 TVLLMXXXXXXXXXXXGTLFSRKIMLPIHRLHKNMKLIGEGNLEIKVFSDSKDEIGDLIR 343 ++++ L S+ I + R+ K+MK + + +I F KDEIG+L Sbjct: 285 FIVILASINLLFPTLLIVLISKSIHSRLLRVLKHMKRMKKQKFDIINFPGDKDEIGELTN 344 Query: 344 GFGSMLGRTKTLIDTVYVGEIARKEYEMK-------ALQAQINPHFLYNSLSLINWRAIR 396 F M LI+ VY I +K+ +++ ALQ+QINPHFL+N+L I R++ Sbjct: 345 EFNKMSQTINRLINEVYASNIEKKDLQLREKQAQLSALQSQINPHFLFNALETIRMRSMI 404 Query: 397 IHATDISEMAQLLSTFYRTTLNKGENLISVSDEILNVQSYINIQLIMHSNSFEIDYQIDD 456 + +++ Q ++ +R +L G++ ++V DE+ + ++ IQ + E + ID+ Sbjct: 405 KGEKETAKIIQNMAKIFRNSLTWGKDWVTVRDELCLIICFLEIQKYRFGDKMEYELDIDE 464 Query: 457 SILSCRMPNLMLQPLIENAIIHGIENREDGGGIIHLSGKKEDQSIVFLITDNGIGVEQER 516 +PN++ P +ENA IHGIE+ ++ GII + +K D IV+ I+DNG G+++E+ Sbjct: 465 EAYDYIIPNMVFLPFVENASIHGIESVKE-KGIIQIRVEKNDGEIVYEISDNGAGMDEEK 523 Query: 517 LALLLKS------QSKGYGLKNVNDRAVVMYGEQYGLTINSIPGEGTQVLLKIPYDEHN 569 LA L+++ + G+KNV R + Y + +INS PG+GT V +K+P +++N Sbjct: 524 LASLIETLKNEENMGENVGIKNVYYRLKLHYKNHFDFSINSRPGQGTTVQIKLPAEKNN 582 >ref|NP_561490.1| two-component sensor histidine kinase [Clostridium perfringens] dbj|BAB80280.1| two-component sensor histidine kinase [Clostridium perfringens str. 13] Length = 529 Score = 164 bits (414), Expect = 8e-39, Method: Compositional matrix adjust. Identities = 99/320 (30%), Positives = 172/320 (53%), Gaps = 7/320 (2%) Query: 247 SGKNYTVLQSSIPITGWKVYLYKPTSLITKSAWWIALTVLLMXXXXXXXXXXXGTLFSRK 306 +G+NY + W + P I + + ++ Sbjct: 212 NGENYVATYRKLKGFNWYIASMTPYDFINADIQSLRKEMTIIGLLFTLVVLIFSYFLYSS 271 Query: 307 IMLPIHRLHKNMKLIGEGNLEIKVFSDSKDEIGDLIRGFGSMLGRTKTLIDTVYVGEIAR 366 I +P++ L MK + EG+L++ V +DEIG + F SML R LI+ + E+ + Sbjct: 272 IKVPLYNLLNKMKRVSEGDLKVLVNDTYEDEIGVISDNFDSMLKRVNELIEKTKLQEVEK 331 Query: 367 KEYEMKALQAQINPHFLYNSLSLINWRAIRIHATDISEMAQLLSTFYRTTLNKGENLISV 426 ++ E++ LQAQINPHFL+N+L+ + W A+ +SE L+ R T+ L+++ Sbjct: 332 RDLEIRMLQAQINPHFLFNTLNSLKWTALMNQDYTVSEGLSSLAELLRNTIIDKNELVTI 391 Query: 427 SDEILNVQSYINIQLIMHSNSFEIDYQIDDSILSCRMPNLMLQPLIENAIIHGI-ENRED 485 +E+ N+++Y+ IQ I + NSF++ Y++D+ +L ++ +LQP++EN+IIHGI EN+E+ Sbjct: 392 REELENIKNYVVIQKIRYGNSFDVQYEVDELLLENKVIKFILQPIVENSIIHGIDENKEN 451 Query: 486 GGGIIHLSGKKEDQSIVFLITDNGIGV-EQERLALLLKSQSKGYGLKNVNDRAVVMYGEQ 544 II + E+++I+ I DNG G +E++ ++ G G NV++R + +G Sbjct: 452 QKIIIKIMS--EEENILISIKDNGKGFNSKEKVK---DNKLSGIGWNNVDERIKLTFGLG 506 Query: 545 YGLTINSIPGEGTQVLLKIP 564 YG TI S +GT V + IP Sbjct: 507 YGTTIYSEVNKGTIVKIVIP 526 >ref|NP_244314.1| two-component sensor histidine kinase [Bacillus halodurans] pir||G84080 two-component sensor histidine kinase BH3447 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07166.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 602 Score = 160 bits (404), Expect = 9e-38, Method: Compositional matrix adjust. Identities = 108/377 (28%), Positives = 182/377 (48%), Gaps = 30/377 (7%) Query: 212 IVITDSNGNSIYSSGAD---------RTNSGIPISDKEADELHWSGKNYTVLQSSIPITG 262 +++ D G+ IYS R + I +E + G+ Y ++ TG Sbjct: 221 LMVVDQKGDPIYSPAPSIMYEQSFDHRFSQNYGIFTEEVE-----GERYQLMYQQSAFTG 275 Query: 263 WKVYLYKPTSLITKSAWWIALTVLLMXXXXXXXXXXXGTLFSRKIMLPIHRLHKNMKLIG 322 W + T + I V+ S I PI++L M+ Sbjct: 276 WTLIGVFSTDQSVEEVQQILFYVVTFVFFVCFVGITASYFLSYTISRPINQLMLAMQKAE 335 Query: 323 EGNLEIKVFSDSKDEIGDLIRGFGSMLGRTKTLIDTVYVGEIARKEYEMKALQAQINPHF 382 G+L + + +DE+G L R F +M+ + LI E ++E E+ +LQA I PHF Sbjct: 336 SGDLTSRYEGEEQDEVGRLGRSFNTMIEQIGKLISLTERQERKKREAELHSLQANIKPHF 395 Query: 383 LYNSLSLINWRAIRIHATDISEMAQLLSTFYRTTLNKGENLISVSDEILNVQSYINIQLI 442 LYN+L I W A + +A+D++++ LS +R L+KG +I + DEI ++++Y+ IQ + Sbjct: 396 LYNTLDTIQWMARKKNASDVADLVGALSKLFRIGLSKGGTIIPLVDEIEHIKNYLQIQSV 455 Query: 443 MHSNSFEIDYQIDDSILSCRMPNLMLQPLIENAIIHGIENREDGGGIIHLSGKKEDQSIV 502 + N + ++ + ++LQP++ENAI HGI+ R G G+I + ++E+ ++ Sbjct: 456 RYKNKLNYSLVMPSNMERLSILKIVLQPIVENAIYHGIKERR-GPGLITIEAERENDMLI 514 Query: 503 FLITDNGIGVEQERLALLL---------------KSQSKGYGLKNVNDRAVVMYGEQYGL 547 I DNG G++ E L L + +KGYGL NV+ R + +GE YG+ Sbjct: 515 IRIRDNGKGIKPETLQQLRTNVNLFLEKGDKEGGQRLTKGYGLINVHARLRLTFGEPYGV 574 Query: 548 TINSIPGEGTQVLLKIP 564 I+S+ EGT V + P Sbjct: 575 KIDSVFNEGTVVTIFHP 591 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.135 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 807,160,573 Number of extensions: 33396129 Number of successful extensions: 93773 Number of sequences better than 1.0e-05: 191 Number of HSP's gapped: 93515 Number of HSP's successfully gapped: 191 Length of query: 569 Length of database: 757,237,578 Length adjustment: 131 Effective length of query: 438 Effective length of database: 401,559,609 Effective search space: 175883108742 Effective search space used: 175883108742 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 129 (54.3 bits)