BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0440.0012.p (391 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_470106.1| similar to transcriptional regulator (LacI fami... 175 1e-42 ref|NP_464297.1| similar to transcriptional regulator (LacI fami... 174 2e-42 sp|Q9S470|ARAR_BACST Arabinose metabolism transcriptional repres... 124 4e-27 ref|NP_607665.1| putative transcription regulator [Streptococcus... 120 5e-26 ref|NP_269658.1| putative transcription regulator [Streptococcus... 118 2e-25 >ref|NP_470106.1| similar to transcriptional regulator (LacI family) [Listeria innocua] pir||AD1528 transcription regulator (LacI family) homolog lin0764 [imported] - Listeria innocua (strain Clip11262) emb|CAC95996.1| lin0764 [Listeria innocua] Length = 372 Score = 175 bits (444), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 123/351 (35%), Positives = 183/351 (52%), Gaps = 17/351 (4%) Query: 10 KKPLYQTIYQSIKEGIQSGKYAPGDQVPTEKELTDMYDVSRLTAKNAMNLLAEEGWIHRV 69 K LYQ +Y +K IQ GK G ++PTE EL +DVS +T K A+ LL ++G+I R Sbjct: 2 KTLLYQKVYDQLKLSIQEGKIPVGSKMPTENELMAQFDVSSITLKKALELLKKDGYISRR 61 Query: 70 SGKGSFVSELAVEQANRSEQRQAR-----LIGLILAGFSDSYGTELLRTMIHELTRRGYH 124 G+FV + + SEQ + R L G I+ F D++GT LL M+ E + H Sbjct: 62 PRVGTFV----INDSPNSEQIETRKFDKPLFGCIMTNFDDTFGTILLSGML-EHSDSKAH 116 Query: 125 AILKISNESQEMETQYLNELIALGVQGILILPVQAEFHNVALLKVTLSNFPIVLVDRRLS 184 I+K S E E + L E I + V GILILP ++F + LL++ FP+V++DR L Sbjct: 117 IIVKKSLGDTEREEEILQEFIEMNVAGILILPASSKFVSPTLLELASQKFPLVVIDRTLE 176 Query: 185 GVSVPYVGSNNKEIAHQLTMKLLNSGHNKISVISHENLNNSSLNDRMDGIRDAYMEKQVX 244 G+ + + S+N E +T KL GH I +I+ + S+L+ R++G + Sbjct: 177 GLPISSISSDNTEAGRIITEKLFELGHKHIGMITSTS-PVSTLDSRVNGFIRGHASFHTA 235 Query: 245 XXXXXXXXXXETSYWNLSDTQLLERDFQKIYQKLQEKPEITCFFALDYLSGQILWYALHQ 304 E+ N T ++ D KI + L+ PEIT A +Y ++ A ++ Sbjct: 236 FHSDYVFREIESVMPN--STVSIQTDIDKIARFLETHPEITALVATEYNIALLIKQACNK 293 Query: 305 IGKSIPEDYSLLSFDGPLQNFLSPS---FTRIIQNQPEIGLHAVGLLLQMI 352 +GKSIP + S++ FD P NF S FT I Q Q EIG+ AV +LL + Sbjct: 294 LGKSIPTNLSVVCFDHP-DNFFDTSAFQFTHIKQAQYEIGVKAVDMLLNQV 343 >ref|NP_464297.1| similar to transcriptional regulator (LacI family) [Listeria monocytogenes EGD-e] pir||AB1171 transcription regulator (LacI family) homolog lmo0770 [imported] - Listeria monocytogenes (strain EGD-e) emb|CAC98848.1| lmo0770 [Listeria monocytogenes] Length = 372 Score = 174 bits (442), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 128/380 (33%), Positives = 192/380 (50%), Gaps = 18/380 (4%) Query: 10 KKPLYQTIYQSIKEGIQSGKYAPGDQVPTEKELTDMYDVSRLTAKNAMNLLAEEGWIHRV 69 KK LYQ +Y +K IQ GK G ++P E EL +DVS +T K A+ LL ++G+I R Sbjct: 2 KKLLYQKVYDQLKLSIQEGKIPVGSKMPAENELMAQFDVSSITLKKALELLKKDGYISRR 61 Query: 70 SGKGSFVSELAVEQANRSEQRQAR-----LIGLILAGFSDSYGTELLRTMIHELTRRGYH 124 G+FV + + SEQ + R L G I+ F D++GT LL M+ E + H Sbjct: 62 PRVGTFV----INASPVSEQIETRMFDKPLFGCIMTNFDDTFGTTLLSGML-EHSDSKAH 116 Query: 125 AILKISNESQEMETQYLNELIALGVQGILILPVQAEFHNVALLKVTLSNFPIVLVDRRLS 184 I+K S E E + L E I + V GILILP ++F + LL++ FP+V++DR L Sbjct: 117 IIVKKSLGDTEREEEILQEFIEMNVAGILILPASSKFVSPTLLELASQKFPLVVIDRTLE 176 Query: 185 GVSVPYVGSNNKEIAHQLTMKLLNSGHNKISVISHENLNNSSLNDRMDGIRDAYMEKQVX 244 G+ + + S+N E +T KL GH I +I+ + S+L+ R++G + Sbjct: 177 GLPISSISSDNTEAGRIITEKLFELGHKHIGMITSTS-PVSTLDSRVNGFIRGHASFHTA 235 Query: 245 XXXXXXXXXXETSYWNLSDTQLLERDFQKIYQKLQEKPEITCFFALDYLSGQILWYALHQ 304 E+ N T ++ D KI L EIT A +Y ++ A ++ Sbjct: 236 FHSDYVFREIESVMPN--STVSIQTDIDKIAHFLNTHSEITALVATEYNIALLIKQACNK 293 Query: 305 IGKSIPEDYSLLSFDGPLQNFLSPS---FTRIIQNQPEIGLHAVGLLLQMIESGQPDYKE 361 +GKSIP D S++ FD P NF S FT I Q Q EIG+ AV +LL + KE Sbjct: 294 LGKSIPADLSVVCFDHP-DNFFDTSAFQFTHIKQAQYEIGVKAVDMLLNQVLKPDTINKE 352 Query: 362 VIVKTRFLDNDSIRINKKQT 381 + ++ DS+++ K + Sbjct: 353 TL-PPMLIEGDSVKMLKSTS 371 >sp|Q9S470|ARAR_BACST Arabinose metabolism transcriptional repressor gb|AAD45715.1| AraR [Geobacillus stearothermophilus] Length = 364 Score = 124 bits (311), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 97/358 (27%), Positives = 171/358 (47%), Gaps = 21/358 (5%) Query: 8 MKKK--PLYQTIYQSIKEGIQSGKYAPGDQVPTEKELTDMYDVSRLTAKNAMNLLAEEGW 65 MK+K P Y + Q I I SG+ P +++PTE E+ + + +SR T + A+ L +EGW Sbjct: 1 MKEKTLPKYLQLKQEILSWIISGQMKPDEKIPTEHEIANQFQLSRHTVRQALGELEKEGW 60 Query: 66 IHRVSGKGSFVSELAVEQANRSEQRQARLIGLILAGFSDSYGTELLRTMIHELTRRGYHA 125 ++++ G G+FVS + EQ + IG++ SD ++R L +GY Sbjct: 61 LYKIQGSGTFVS-----RPKPKEQVDTKTIGIVTTYISDYIFPHIVRGAEETLREKGYRL 115 Query: 126 ILKISNESQEMETQYLNELIALGVQGILILPVQAEFHNVAL-LKVTLSNF--PIVLVDRR 182 +L +N ++ E + L E+I + G++I P ++ N + ++L+N P V+++ R Sbjct: 116 LLASTNNDKQREKEQLEEMIREPLSGLIIEPTKSAQGNPNMGYYLSLNNLHIPYVMINAR 175 Query: 183 LSGVSVPYVGSNNKEIAHQLTMKLLNSGHNKIS-VISHENLNNSSLNDRMDGIRDAYMEK 241 VS P V ++++ LT L+ GH +I+ ++L DR+ G A+ + Sbjct: 176 YLEVSCPCVKMDDEQGGFLLTDHLIRLGHRRIAGFFKTDDLQGV---DRLRGFIRAHQQH 232 Query: 242 QVXXXXXXXXXXXETSYWNLSDTQLLERDFQKIYQKLQEKPEITCFFALDYLSGQILWYA 301 +V W T+ LE + + + +E+P T F + +L Sbjct: 233 EVPVATEYLLSYATEEKW----TKPLEVAREFLQRPKEERP--TAFVCYNDELAILLLEV 286 Query: 302 LHQIGKSIPEDYSLLSFDG-PLQNFLSPSFTRIIQNQPEIGLHAVGLLLQMIESGQPD 358 + Q G S+P+D S++ FD T I + E+G+ A +L+QMIE D Sbjct: 287 IRQQGLSVPDDISIVGFDDFTFATATEVKLTTIRHPKTEMGVQAAEMLIQMIEQRSVD 344 >ref|NP_607665.1| putative transcription regulator [Streptococcus pyogenes MGAS8232] gb|AAL98164.1| putative transcription regulator [Streptococcus pyogenes MGAS8232] Length = 346 Score = 120 bits (301), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 103/352 (29%), Positives = 176/352 (50%), Gaps = 31/352 (8%) Query: 11 KPLYQTIYQSIKEGIQSGKYAPGDQVPTEKELTDMYDVSRLTAKNAMNLLAEEGWIHRVS 70 K LY+ IY IKE I SG+ GD++PTEKEL++ + VSR+T+K A+ L +EG I R Sbjct: 3 KLLYKKIYHFIKEQIASGRLQIGDRLPTEKELSEQFSVSRITSKRALVELEQEGLITRSR 62 Query: 71 GKGSFVSELAVEQANRSEQRQARLIGLILAGFSDSYGTELLRTMIHELTRRGYHAILKIS 130 GKGSFV++ +Q E + L LIL SD + + ++ + GY +++++ Sbjct: 63 GKGSFVAK---KQVTSPEANKDLL--LILPFASDYELGDYAKGIMTSIAETGYRLMVQLA 117 Query: 131 NESQEMETQYLNELIALGVQGILILPVQAEFHNVALLKVTLSNFPIVLVDRRLSGVSVPY 190 + T L+ L GI+ P L + P+VL+D+ L P Sbjct: 118 S------TVRLDTLSDYA--GIIYYPEDVNHSIDFLFYCDHHHIPLVLLDKSLDLFQFPA 169 Query: 191 VGSNNKEIAHQLTMKLLNSGHNKISVISHENLNN-SSLNDRMDGIRDAYMEKQVXXXXXX 249 V ++NK A+QLT L++ G ++I ++ E+ SS+ DR G A E + Sbjct: 170 VVADNKGGAYQLTQHLIDQGCDQIWFVAIESFGEVSSVRDRYLGYLAAMAESSL------ 223 Query: 250 XXXXXETSYWNLSDTQLLERDFQKIYQKLQEKPEITCFFAL--DYLSGQILWYALHQIGK 307 ++ Y+ ++T+ + +++ + L E + D+L+ Q++ + Q+G Sbjct: 224 -----KSHYFPKTETETTDAYLERLVKTLSETTATKKGLVVENDWLAIQLIQ-KITQVGL 277 Query: 308 SIPEDYSLLSFD-GPLQNFLSPSFTRIIQNQPEIGLHAVGLLLQMIESGQPD 358 SIP+ +++ FD LSP + Q+ ++G A +LLQ+I +PD Sbjct: 278 SIPDQVAIVGFDNNQASRLLSPKLSTAAQDFYQMGQEAAKVLLQIIH--EPD 327 >ref|NP_269658.1| putative transcription regulator [Streptococcus pyogenes] gb|AAK34379.1| putative transcription regulator [Streptococcus pyogenes M1 GAS] Length = 346 Score = 118 bits (296), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 103/352 (29%), Positives = 173/352 (49%), Gaps = 31/352 (8%) Query: 11 KPLYQTIYQSIKEGIQSGKYAPGDQVPTEKELTDMYDVSRLTAKNAMNLLAEEGWIHRVS 70 K LY+ IY IKE I SG+ GD++PTEKEL++ + VSR+T+K A+ L +EG I R Sbjct: 3 KLLYKKIYHFIKEQIASGRLQIGDRLPTEKELSEQFSVSRITSKRALVELEQEGLITRSR 62 Query: 71 GKGSFVSELAVEQANRSEQRQARLIGLILAGFSDSYGTELLRTMIHELTRRGYHAILKIS 130 GKGSFV++ +Q E + L LIL SD + + ++ + GY +++++ Sbjct: 63 GKGSFVAK---KQVTSPEANKDLL--LILPFASDYELGDYAKGIMTSIAETGYRLMVQLA 117 Query: 131 NESQEMETQYLNELIALGVQGILILPVQAEFHNVALLKVTLSNFPIVLVDRRLSGVSVPY 190 + T L+ L GI+ P L + P+VL+D+ L P Sbjct: 118 S------TVRLDTLSDYA--GIIYYPEDVNHSIDFLFYCDHHHIPLVLLDKSLDLFQFPS 169 Query: 191 VGSNNKEIAHQLTMKLLNSGHNKISVISHENLNN-SSLNDRMDGIRDAYMEKQVXXXXXX 249 V ++NK A QLT L+ G ++IS ++ + SS+ DR G A E + Sbjct: 170 VVADNKGGACQLTQHLIEQGCDQISFVATGSFGEVSSVRDRYLGYLAAMAESSL------ 223 Query: 250 XXXXXETSYWNLSDTQLLERDFQKIYQKLQEKPEITCFFAL--DYLSGQILWYALHQIGK 307 ++ Y+ ++T+ + ++ + L E + D+L+ Q++ + Q+G Sbjct: 224 -----KSHYFPKTETETTDAYLDRLVKTLSETTATKRGLVVENDWLAIQLIQ-KITQVGL 277 Query: 308 SIPEDYSLLSFDGP-LQNFLSPSFTRIIQNQPEIGLHAVGLLLQMIESGQPD 358 SIP+ +++ FD LSP + Q+ ++G A +LLQ+I +PD Sbjct: 278 SIPDQVAIVGFDNSQASRLLSPKLSTAAQDFYQMGQEAAKVLLQIIH--EPD 327 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.316 0.134 0.377 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 547,609,021 Number of extensions: 22216825 Number of successful extensions: 61524 Number of sequences better than 1.0e-05: 435 Number of HSP's gapped: 61635 Number of HSP's successfully gapped: 435 Length of query: 391 Length of database: 757,237,578 Length adjustment: 128 Effective length of query: 263 Effective length of database: 409,704,906 Effective search space: 107752390278 Effective search space used: 107752390278 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 127 (53.5 bits)