BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0437.0027.p (588 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongen... 168 4e-40 ref|NP_244545.1| two-component sensor histidine kinase [Bacillus... 163 1e-38 ref|NP_782429.1| two-component sensor kinase yesM [Clostridium t... 163 1e-38 ref|NP_388576.1| similar to two-component sensor histidine kinas... 162 2e-38 ref|NP_561490.1| two-component sensor histidine kinase [Clostrid... 162 2e-38 >ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongensis] gb|AAM25485.1| predicted ATPase [Thermoanaerobacter tengcongensis] Length = 593 Score = 168 bits (425), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 141/605 (23%), Positives = 290/605 (47%), Gaps = 43/605 (7%) Query: 1 MKMTFRYRLLASYIFLITIPLLVLGTLFYRTSLQIITEQAQKNVYELVKKNNEVMDTKLR 60 M + R+++L + ++ I L++ Y S+ + ++ ++ K+ +D R Sbjct: 10 MGLNIRHKILILFYGIVVITSLLIVFFSYTISINQLKKEVGNSLLRDTKRIAASIDFLQR 69 Query: 61 IVDQNSMSLFLDKDLFRIFNQLDPANEAGLFEADRQVTAILGKYFSQNQDIYAYQLWTSY 120 V++ S L LD+ RI N + P ++ + + + K + +Y++Q Y Sbjct: 70 DVNELSSFLVLDQ---RIQNFISPHSDFTKYSLGPLASLLASKDYISFIALYSFQGDKYY 126 Query: 121 FTFGQTLPQGD---PTQSDIYEMALQAGGKLVWVPTYDFVSMFHQPYLQSGNLEFRYLFS 177 F+ + D ++ Y L+ G +W+ S+ + P+ + + Sbjct: 127 FSNDSSTLIMDLELIKRTSFYREVLEKNGAPMWL------SLENLPFDLIIKNNYPKIAM 180 Query: 178 ATRVLDFTYLGNTKLEKMNARAERPVLAISFKSEVLKSLYADSIS-GSARYMVLDPHDKV 236 A +LDF N +L I ++ +Y++++ + + + D + + Sbjct: 181 ARVLLDF-----------NTYKPEGLLVICINIPTIEKVYSENLKEKESAFFIADRNGNI 229 Query: 237 VA--SSEPGAVARTSKEAWLDELKQERSGARRMTLDGEAVIVCFDRSEVTGW--MSVVWI 292 ++ S+ G ++++ LK +++ + ++ ++V + W +SVV + Sbjct: 230 ISFKSTFSGFTPKSAQNILAKYLKDKQNVV--ININSSKLLVTSSPIPTSDWRLVSVVSL 287 Query: 293 PEAGLLSSFVPVIRTSITVLAVVXXXXXXXXXXXXXXKITKPIKRLLSAMRSVGEGDFQT 352 A + S + I + +L V +T P++RL ++M+ V +G+ + Sbjct: 288 KNA-INSIRISFIEFYLRIL-VFCLLFAFLVSMYFSRALTHPLERLANSMKKVRQGNLEE 345 Query: 353 RVEVV--TNDEFGMLTKRFNRMNDRIHLLVTENYEIKLKEKEAEIQALTMQMHPHFLYNT 410 +VE + DE ++ K +NRM +RI+ L+ ++++ ++EAE++AL Q++PHFLYNT Sbjct: 346 KVEFEYHSKDEIAIVIKEYNRMVERINDLINRILKLEINKREAELKALEAQINPHFLYNT 405 Query: 411 LNVMNWTAIENGQQELSRMLVCLSNMLHYTSRKTWDAVHLSEEMNWMDNYFYIMSIRFED 470 L+ + W A + +ELS M+ LS + T + + + + E ++ Y ++ S R+++ Sbjct: 406 LDTIFWKAEKAKDRELSEMIYSLSRLFRLTLNRGEEFIQVRGEKELIERYLFLQSKRYKN 465 Query: 471 KFTVEYAIDPQLYEYDVPRLLFQPFVENAILHGFNQTESGGMIRIRGWIAEGTRF-YEVA 529 KF I ++ +Y +P+L+ QPFVENAI+HG + + G EG + + Sbjct: 466 KFKYSVKISDEILDYYIPKLILQPFVENAIVHGLENNSEESFVEVIGE-KEGENLKFIIK 524 Query: 530 DNGRGMSQETVQAI-LYQKSSSV------GIKNTIDRIQIAYGTLYGVSIVSAPGEGTRV 582 DNG GMS+ET++ + + +S ++ I+N +R+++ YG Y + I S GEGT + Sbjct: 525 DNGPGMSEETLEKLKRFIESENIEEKVGYAIRNVNERLRLYYGDKYELKIESRQGEGTTI 584 Query: 583 VITLP 587 + LP Sbjct: 585 SLILP 589 >ref|NP_244545.1| two-component sensor histidine kinase [Bacillus halodurans] pir||F84109 two-component sensor histidine kinase BH3678 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07397.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 605 Score = 163 bits (413), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 146/615 (23%), Positives = 274/615 (44%), Gaps = 78/615 (12%) Query: 4 TFRYRLLASYIFLITIPLLVLGTLFYRTSLQIITEQAQKNVYELVKKNNEVMDTKLRIVD 63 T R ++ ++I ++ + LL +G + + + I+ A+K + + + +D++ ++ Sbjct: 22 TLRNQIFINFISVMVVVLLFVGFITFNLVMDILKGNAEKQMEQTAIETLHRVDSQFEAIE 81 Query: 64 QNSMSLFLDKDLFRI-FNQLDPANEAGLFEADRQVTAILGKYFSQNQDIYAYQLW-TSY- 120 + + + ++ +N+ + FE + + ++ Y + I +++L+ T Y Sbjct: 82 MIMSQIATNGSIQQLLYNEAN--GHPTTFEQRQSMNQVINSYQAYITGITSFELYFTDYR 139 Query: 121 --FTFGQTLPQGDPTQSDIYEMALQAGGKLVWVP----------TYDFVSMFHQPYLQSG 168 F + LP + + EMAL+ G++VW T V++ Q + G Sbjct: 140 RLFPLNE-LPLPSRIRYEWIEMALEENGRVVWSGIDPLDADSFLTLKKVNLLDQDFSHGG 198 Query: 169 NLEFRYLFSATRVLDFTYLGNTKLEKMNARAERPVLAISFKSEVLKSLYADSISGSARYM 228 YL S F +L + N + + +Y+ Sbjct: 199 -----YLVSKVNTNYF------ELRQENGQ----------------------LDMDNQYV 225 Query: 229 VL-DPHDKVVASSEPGAVARTSKEAWLDELKQERSGARRMTLDGEAVIVCFDRSEVTGWM 287 L D + + ++ P E W D++ ++ + +T+DG + S TGW Sbjct: 226 ALFDQQGQFITTNMP--------EEWHDQIA-PKTDKQVVTMDGTDYVRVEAASNKTGWS 276 Query: 288 SVVWIPEAGLLSSFVPVIRTSITVLAVVXXXXXXXXXXXXXXKITKPIKRLLSAMRSVGE 347 +++ P L+ + I T+I V + IT PI+RL AMR Sbjct: 277 LLIYTP-VHSLAQGITGIGTAILVAGGIGLLIFTISTYFLSSLITNPIQRLTHAMRFGTL 335 Query: 348 GDFQTRVEVVTNDEFGMLTKRFNRMNDRIHLLVTENYEIKLKEKEAEIQALTMQMHPHFL 407 G + + + E L +NRM + + L+ YE +L + AE++AL Q++PHFL Sbjct: 336 GALKESPSIASTVELNELNDTYNRMVETTNYLIKVVYEQELTQSRAELKALQSQINPHFL 395 Query: 408 YNTLNVMNWTAIENGQQELSRMLVCLSNMLHYT--SRKTWDAVHLSEEMNWMDNYFYIMS 465 +NTL + W ++E +E + +++ L+ + YT K D V L EE + ++ Y +IM Sbjct: 396 FNTLEALYW-SLEEKDEEQAEVVIALAELFRYTISDVKGDDWVALHEEFDHIERYLHIMK 454 Query: 466 IRFEDKFTVEYAIDPQLYEYDVPRLLFQPFVENAILHGFNQTESGGMIRIRGW--IAEGT 523 +R++ + E +DP L E +P+LL QP VENAI+HG GG +++ + + +G Sbjct: 455 LRYDHRLAWEIELDPSLREVQIPKLLIQPVVENAIIHGIGNKVDGGKVQVSAYTSVKQGY 514 Query: 524 RFYEVADNGRGMSQETVQAILY---------QKSSSVGIKNTIDRIQIAYGTLYGVSI-- 572 V D+G+GM ++T Q + + +K S + + N R+ + Y + SI Sbjct: 515 VNITVRDDGQGMDEKTKQKLEHSLETRVGHPEKRSGIALVNIRQRLDLCYASDPHTSIEL 574 Query: 573 VSAPGEGTRVVITLP 587 S G GT V T+P Sbjct: 575 TSRHGVGTTVTFTIP 589 >ref|NP_782429.1| two-component sensor kinase yesM [Clostridium tetani E88] gb|AAO36366.1| two-component sensor kinase yesM [Clostridium tetani E88] Length = 577 Score = 163 bits (412), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 88/263 (33%), Positives = 153/263 (58%), Gaps = 5/263 (1%) Query: 331 ITKPIKRLLSAMRSVGEGDFQTRVEVVTNDEFGMLTKRFNRMNDRIHLLVTENYEIKLKE 390 I KPI RL S M + +G+F + E+ NDE +L + FN+M I L+ + Y+++ ++ Sbjct: 306 IVKPIHRLKSNMLEISKGNFDSYYEIKNNDEISILGQVFNQMLTDIKRLINKVYQVEKQK 365 Query: 391 KEAEIQALTMQMHPHFLYNTLNVMNWTAIENGQQELSRMLVCLSNMLHYTSRKTWDAVHL 450 + AE++ L Q++PHFLYNTL+ + W A+E E+ M+ LSN + + + + Sbjct: 366 RSAELRVLQSQINPHFLYNTLDTIQWKALEYNAFEVVDMINYLSNFFRISLSDGKEFITI 425 Query: 451 SEEMNWMDNYFYIMSIRFEDKFTVEYAIDPQLYEYDVPRLLFQPFVENAILHGFNQTESG 510 S+E+ + NY I IR++DK + +D L +Y +P+L+ QP VEN+I HG + Sbjct: 426 SDEVAHVSNYLEIQKIRYKDKISYSMDVDSSLDQYLIPKLIVQPLVENSIYHGLKLQKHK 485 Query: 511 GMIRIRGWIAEGTRFYEVADNGRGMSQE---TVQAILYQ--KSSSVGIKNTIDRIQIAYG 565 G+I + +G F +V DNG GM E T++ L++ +++ G+ N +R+++A+G Sbjct: 486 GIINVSISSKDGFLFIKVIDNGLGMDVEQLRTLRKNLWESIETNHYGLYNINERLKLAFG 545 Query: 566 TLYGVSIVSAPGEGTRVVITLPV 588 Y + I S GT+V++ +P+ Sbjct: 546 KKYSIEIKSELKIGTQVLLRIPL 568 >ref|NP_388576.1| similar to two-component sensor histidine kinase [YesN] [Bacillus subtilis] pir||D69796 two-component sensor histidine kinase homolog yesM - Bacillus subtilis emb|CAB12514.1| yesM [Bacillus subtilis subsp. subtilis str. 168] Length = 577 Score = 162 bits (410), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 94/262 (35%), Positives = 143/262 (54%), Gaps = 7/262 (2%) Query: 331 ITKPIKRLLSAMRSVGEGDFQTRVEVV----TNDEFGMLTKRFNRMNDRIHLLVTENYEI 386 IT+PI++L++AM+SV + V + T DE GML + F M RI+ L+ EN E Sbjct: 314 ITEPIEQLVTAMKSVQHSGIEAGVSLSLPEHTQDEAGMLNRHFTVMMKRINELMEENVEK 373 Query: 387 KLKEKEAEIQALTMQMHPHFLYNTLNVMNWTAIENGQQELSRMLVCLSNMLHYTSRKTWD 446 +L KE E++AL Q++PHFLYNTL +NW A N Q+++S+M+ L +L + D Sbjct: 374 QLIIKETELKALQAQINPHFLYNTLESINWLAKANQQKQISKMVESLGFLLRNSIHMKKD 433 Query: 447 AVHLSEEMNWMDNYFYIMSIRFEDKFTVEYAIDPQLYEYDVPRLLFQPFVENAILHGFNQ 506 V + EE + + +Y I RFE++ ID ++ +P+L QP ENAI + Sbjct: 434 IVTIQEEADIVRHYMTIQRFRFEERLKFTLDIDDEVKHCLIPKLTLQPLAENAIQYALEP 493 Query: 507 TESGGMIRIRGWIAEGTRFYEVADNGRGMSQETVQAILYQKSSSVGIKNTIDRIQIAYGT 566 IRI+ A+G V DNG GM +++ +G+ N +RI + +G Sbjct: 494 FTRPCAIRIQAKKAKGCVCITVEDNGPGMDGRILEST---GGRGIGLWNIRERISLTFGE 550 Query: 567 LYGVSIVSAPGEGTRVVITLPV 588 YG+ I S +GTR+VIT+P Sbjct: 551 PYGLRIHSEHEKGTRIVITIPC 572 >ref|NP_561490.1| two-component sensor histidine kinase [Clostridium perfringens] dbj|BAB80280.1| two-component sensor histidine kinase [Clostridium perfringens str. 13] Length = 529 Score = 162 bits (410), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 96/331 (29%), Positives = 169/331 (51%), Gaps = 5/331 (1%) Query: 258 KQERSGARRMTLDGEAVIVCFDRSEVTGWMSVVWIPEAGLLSSFVPVIRTSITVLAVVXX 317 K + AR + ++GE + + + + W P +++ + +R +T++ ++ Sbjct: 200 KGAKDTARSIVVNGENYVATYRKLKGFNWYIASMTP-YDFINADIQSLRKEMTIIGLLFT 258 Query: 318 XXXXXXXXXXXXKITKPIKRLLSAMRSVGEGDFQTRVEVVTNDEFGMLTKRFNRMNDRIH 377 I P+ LL+ M+ V EGD + V DE G+++ F+ M R++ Sbjct: 259 LVVLIFSYFLYSSIKVPLYNLLNKMKRVSEGDLKVLVNDTYEDEIGVISDNFDSMLKRVN 318 Query: 378 LLVTENYEIKLKEKEAEIQALTMQMHPHFLYNTLNVMNWTAIENGQQELSRMLVCLSNML 437 L+ + ++++++ EI+ L Q++PHFL+NTLN + WTA+ N +S L L+ +L Sbjct: 319 ELIEKTKLQEVEKRDLEIRMLQAQINPHFLFNTLNSLKWTALMNQDYTVSEGLSSLAELL 378 Query: 438 HYTSRKTWDAVHLSEEMNWMDNYFYIMSIRFEDKFTVEYAIDPQLYEYDVPRLLFQPFVE 497 T + V + EE+ + NY I IR+ + F V+Y +D L E V + + QP VE Sbjct: 379 RNTIIDKNELVTIREELENIKNYVVIQKIRYGNSFDVQYEVDELLLENKVIKFILQPIVE 438 Query: 498 NAILHGFNQTESGGMIRIRGWIAEGTRFYEVADNGRGM-SQETVQAILYQKSSSVGIKNT 556 N+I+HG ++ + I I+ E + DNG+G S+E V+ K S +G N Sbjct: 439 NSIIHGIDENKENQKIIIKIMSEEENILISIKDNGKGFNSKEKVKD---NKLSGIGWNNV 495 Query: 557 IDRIQIAYGTLYGVSIVSAPGEGTRVVITLP 587 +RI++ +G YG +I S +GT V I +P Sbjct: 496 DERIKLTFGLGYGTTIYSEVNKGTIVKIVIP 526 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.321 0.135 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 812,501,669 Number of extensions: 32119947 Number of successful extensions: 88970 Number of sequences better than 1.0e-05: 209 Number of HSP's gapped: 88793 Number of HSP's successfully gapped: 209 Length of query: 588 Length of database: 757,237,578 Length adjustment: 131 Effective length of query: 457 Effective length of database: 401,559,609 Effective search space: 183512741313 Effective search space used: 183512741313 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 129 (54.3 bits)