BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0437.0002.p (365 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_391201.1| similar to two-component sensor histidine kinas... 192 8e-48 emb|CAB60253.1| MrsK2 protein [Bacillus sp. HIL-Y85/54728] 175 1e-42 ref|NP_977539.1| sensor histidine kinase [Bacillus cereus ATCC 1... 172 1e-41 ref|NP_830904.1| Two-component sensor kinase yvrG [Bacillus cere... 165 1e-39 ref|NP_655026.1| HATPase_c, Histidine kinase-like ATPases [Bacil... 164 4e-39 >ref|NP_391201.1| similar to two-component sensor histidine kinase [YvrH] [Bacillus subtilis] pir||B70047 two-component sensor histidine kinase homolog yvrG - Bacillus subtilis emb|CAB15311.1| yvrG [Bacillus subtilis subsp. subtilis str. 168] emb|CAA11731.1| putative sensory protein kinase, YvrG [Bacillus subtilis] Length = 573 Score = 192 bits (489), Expect = 8e-48, Method: Compositional matrix adjust. Identities = 110/328 (33%), Positives = 173/328 (52%), Gaps = 22/328 (6%) Query: 55 SFLAVCLAAL---------------AFYLWSLMKPVFYMLTWLKRLAQGHYDEPSRSNWR 99 SFL V L A+ +Y++ P+F+ + WL L++G +EP N Sbjct: 246 SFLKVVLKAMFLVMAVLFMYIIWMTVWYMFRFGLPIFHTIRWLVNLSKGKLEEPR--NRE 303 Query: 100 GRPLSGNQ---LKLPYTLFREIIGQMSMLTLALQXXXXXXXXXXXXXXSWIAGVRHDLKT 156 GRP+S N+ +K PY F EI M LT L+ WIAG+ HDLKT Sbjct: 304 GRPVSKNKKGKIKQPYRFFGEIFESMDQLTETLRRDKRNREKIQATREEWIAGLSHDLKT 363 Query: 157 PLAYIRGYSSMIAAADQYQWSTAEIIQFGSLMEQKTIQVEQLIEDMNASYQLDGSEGPLS 216 PL+ I GYS M+ + QY WS E + G ++ +K+ + +LIED+N +Y+L P+ Sbjct: 364 PLSSIYGYSMMLESK-QYDWSPEEGEEMGQVVREKSEYMSKLIEDLNLTYRLKNDALPIE 422 Query: 217 RESTEMAGFIRQIVTDVADHPLAAQHTFAFNTAGEKC-LDIDQRMIRRALHNLLWNAVVH 275 R+ T + F + ++ D +P + + +F + E +D+ RR L NLL NAV H Sbjct: 423 RKLTSLIPFFKNVIEDFKKNPFSEGYDISFVSKEEHIEFALDEAWFRRILENLLGNAVKH 482 Query: 276 NPAGCHIEAEVYWDQHGLTVEIRDNGTGIDAETLERLNTAEDNVLSARARLAGSGLGMAL 335 N G I+ + ++ ++++++DNG G+D ET+ L + + AG+GLG+A+ Sbjct: 483 NGKGTEIQVILEQTKNHISLKVKDNGKGMDEETITHLFNRYYRGTNTKDSTAGTGLGLAI 542 Query: 336 AKGFVTRHDGTMTVHSKPQQGTRITLFF 363 AK V H+GT+ V+S+ GT IT+ F Sbjct: 543 AKELVHLHNGTIHVNSRTNIGTVITILF 570 >emb|CAB60253.1| MrsK2 protein [Bacillus sp. HIL-Y85/54728] Length = 479 Score = 175 bits (444), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 95/315 (30%), Positives = 168/315 (53%), Gaps = 7/315 (2%) Query: 53 IWSFLAVCLAALAFYLWSLMKPVFYMLTWLKRLAQGHYDEPSRSNWRGRPLSGNQLKLPY 112 I S + + FY L P+ ++++W++ L++ Y+EP +W+ K Y Sbjct: 157 IVSIIMAGIVIAIFYGKKLGAPLLFIVSWIENLSKEKYEEPY--DWKFHSSKYRHNKSGY 214 Query: 113 TLFREIIGQMSMLTLALQXXXXXXXXXXXXXXSWIAGVRHDLKTPLAYIRGYSSMIAAAD 172 ++E++ +S LT LQ W+AGV HDLKTPL+ I+GY+ ++++ + Sbjct: 215 KTYQELMQALSELTSTLQRNKAERELLEKTREEWMAGVSHDLKTPLSVIKGYTVLLSS-N 273 Query: 173 QYQWSTAEIIQFGSLMEQKTIQVEQLIEDMNASYQLDGSEGPLSRESTEMAGFIRQIVTD 232 +Y+W ++ F +ME++ +E+LIED N ++QL P+ E + I + Sbjct: 274 EYEWENQQVRDFSLIMEERVEYMEKLIEDFNLTFQLKNESLPIHLEEKNVVKVIHDTLEK 333 Query: 233 VADHPLAAQHTFAFNTAGEKCL-DIDQRMIRRALHNLLWNAVVHNPAGCHIEAEVYWD-- 289 + P + FA ++ K L ++D+R ++RA+ NL+ N + HNP G I+ +Y D Sbjct: 334 MKLLPESENKRFALESSHNKILFNMDERYLKRAVENLIANCIKHNPPGTKIKVILYQDVL 393 Query: 290 -QHGLTVEIRDNGTGIDAETLERLNTAEDNVLSARARLAGSGLGMALAKGFVTRHDGTMT 348 + + + I D+G G+D ET+E L SA + +G+GLGMA+A+ + H G + Sbjct: 394 HDNEIQIIIEDDGIGMDEETVECLFDRYFRGTSATSNNSGTGLGMAIAQQIIKAHGGNID 453 Query: 349 VHSKPQQGTRITLFF 363 ++S+P GTR + F Sbjct: 454 IYSQPGIGTRFKITF 468 >ref|NP_977539.1| sensor histidine kinase [Bacillus cereus ATCC 10987] gb|AAS40147.1| sensor histidine kinase [Bacillus cereus ATCC 10987] Length = 580 Score = 172 bits (436), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 98/306 (32%), Positives = 165/306 (53%), Gaps = 25/306 (8%) Query: 73 KPVFYMLTWLKRLAQGHYDEPSRSNWRGRPL----SGNQLKLPYTLFREIIGQMSMLTLA 128 KP+ + + WLK +A G Y+EP +G+P+ SG + K + LFR++ + L++ Sbjct: 285 KPLLHAMRWLKNIAGGKYEEPVSK--KGKPIRFRRSGKE-KWSFRLFRDVTSSLEHLSIT 341 Query: 129 LQXXXXXXXXXXXXXXSWIAGVRHDLKTPLAYIRGYSSMIAAADQYQWSTAEIIQFGSLM 188 LQ WI G+ HDLKTPL+ I GY+ ++ + QY W+ +I QFGS+M Sbjct: 342 LQKNDAMRQVLQQTREEWITGLTHDLKTPLSSIYGYA-LLLESKQYNWTDRDIQQFGSVM 400 Query: 189 EQKTIQVEQLIEDMNASYQLDGSEGPLSRESTEMAGFIRQIVTDVADHPLAAQHTFAFNT 248 ++K+ + LI+D++ +YQL + P + EM F+++++ ++P F Sbjct: 401 KEKSQYMTTLIDDLSLTYQLKNNSLPAQHVNIEMNQFVQKVLLQFINNPTLQNQNIEFVP 460 Query: 249 AGEKC-LDIDQRMIRRALHNLLWNAVVHNPAGCHIEAEVYWDQHGLTVEIRDNGTGIDAE 307 + K I+++ +R + NLL NAV HN ++ ++ +++ T+ I DNG G+D + Sbjct: 461 SSNKIQYFIEEKWFQRIIENLLVNAVKHNNETTNVIVKLSQNENSFTLSISDNGKGMDDK 520 Query: 308 TLERL--------NTAEDNVLSARARLAGSGLGMALAKGFVTRHDGTMTVHSKPQQGTRI 359 T E L NT E N+ G+GLG+A+ K V H+GT+++ S+ +GT I Sbjct: 521 TKELLFERYYRGTNTEESNI--------GTGLGLAITKQLVHAHNGTISIDSELGKGTTI 572 Query: 360 TLFFLF 365 L F F Sbjct: 573 ILVFPF 578 >ref|NP_830904.1| Two-component sensor kinase yvrG [Bacillus cereus ATCC 14579] gb|AAP08105.1| Two-component sensor kinase yvrG [Bacillus cereus ATCC 14579] Length = 580 Score = 165 bits (418), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 96/306 (31%), Positives = 163/306 (53%), Gaps = 25/306 (8%) Query: 73 KPVFYMLTWLKRLAQGHYDEPSRSNWRGRPL----SGNQLKLPYTLFREIIGQMSMLTLA 128 KP+ + + WLK +A G Y+EP +G+P+ SG + K + LFR++ + L++ Sbjct: 285 KPLLHAMRWLKNIAGGKYEEPISK--KGKPVRFRRSGKE-KWSFRLFRDVTSSLEHLSIT 341 Query: 129 LQXXXXXXXXXXXXXXSWIAGVRHDLKTPLAYIRGYSSMIAAADQYQWSTAEIIQFGSLM 188 L+ WI G+ HDLKTPL+ I GY+ ++ ++QY W+ +I QFGS+M Sbjct: 342 LKKNDAMRQVLQQTREEWITGLTHDLKTPLSSIYGYA-LLLESNQYNWTDRDIQQFGSVM 400 Query: 189 EQKTIQVEQLIEDMNASYQLDGSEGPLSRESTEMAGFIRQIVTDVADHPLAAQHTFAFNT 248 ++K+ + LI+D++ +YQL + P + E+ F+++++ ++P F Sbjct: 401 KEKSQYMTTLIDDLSLTYQLKNNSLPAQHVNVEINQFVQKVLLQFINNPTLQNQNIEFVP 460 Query: 249 AGEKC-LDIDQRMIRRALHNLLWNAVVHNPAGCHIEAEVYWDQHGLTVEIRDNGTGIDAE 307 + K I+++ +R + NLL NAV HN + ++ + + T+ I D+G G+D + Sbjct: 461 SSNKIQYFIEEKWFQRIIENLLVNAVKHNNETTTVIVKLSQNANSFTLSISDDGKGMDEK 520 Query: 308 TLERL--------NTAEDNVLSARARLAGSGLGMALAKGFVTRHDGTMTVHSKPQQGTRI 359 T E L NT E N+ G+GLG+A+ K V H+GT++V S +GT I Sbjct: 521 TKELLFERYYRGTNTEESNI--------GTGLGLAITKQLVHAHNGTISVDSALGKGTTI 572 Query: 360 TLFFLF 365 L F F Sbjct: 573 ILVFPF 578 >ref|NP_655026.1| HATPase_c, Histidine kinase-like ATPases [Bacillus anthracis A2012] ref|NP_843604.1| sensor histidine kinase [Bacillus anthracis str. Ames] gb|AAP25090.1| sensor histidine kinase [Bacillus anthracis str. Ames] Length = 580 Score = 164 bits (414), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 95/306 (31%), Positives = 161/306 (52%), Gaps = 25/306 (8%) Query: 73 KPVFYMLTWLKRLAQGHYDEPSRSNWRGRPL----SGNQLKLPYTLFREIIGQMSMLTLA 128 KP+ + + WLK +A G Y+EP +G+P+ SG + K + LF ++ + L++ Sbjct: 285 KPLLHAMRWLKNIAGGKYEEPVSK--KGKPIRFRKSGKE-KWSFRLFSDVTNSLEHLSIT 341 Query: 129 LQXXXXXXXXXXXXXXSWIAGVRHDLKTPLAYIRGYSSMIAAADQYQWSTAEIIQFGSLM 188 L+ WI G+ HDLKTPL+ I GY+ ++ + QY W+ +I QFGS+M Sbjct: 342 LKKNDAMRQVLQQTREEWITGLTHDLKTPLSSIYGYA-LLLESKQYNWTDRDIQQFGSVM 400 Query: 189 EQKTIQVEQLIEDMNASYQLDGSEGPLSRESTEMAGFIRQIVTDVADHPLAAQHTFAFNT 248 ++K+ + LI+D++ +YQL + P + EM F+++++ ++P F Sbjct: 401 KEKSQYMTTLIDDLSLTYQLKNNSLPAQHVNIEMNQFVQKVLLQFINNPTLQNQNIEFVP 460 Query: 249 AGEKC-LDIDQRMIRRALHNLLWNAVVHNPAGCHIEAEVYWDQHGLTVEIRDNGTGIDAE 307 + K I+++ +R + NLL NAV HN ++ ++ + T+ I DNG G+D + Sbjct: 461 SSNKIQYFIEEKWFQRIIENLLVNAVKHNNETTNVIVKLSQNATSFTLSISDNGKGMDDK 520 Query: 308 TLERL--------NTAEDNVLSARARLAGSGLGMALAKGFVTRHDGTMTVHSKPQQGTRI 359 T E L NT E N+ G+GLG+A+ K V H+G +++ S+ +GT I Sbjct: 521 TKELLFERYYRGTNTEESNI--------GTGLGLAITKQLVHAHNGAISIDSELGKGTTI 572 Query: 360 TLFFLF 365 L F F Sbjct: 573 ILVFPF 578 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.324 0.136 0.423 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 465,476,022 Number of extensions: 17326661 Number of successful extensions: 65636 Number of sequences better than 1.0e-05: 1411 Number of HSP's gapped: 65574 Number of HSP's successfully gapped: 1411 Length of query: 365 Length of database: 757,237,578 Length adjustment: 127 Effective length of query: 238 Effective length of database: 412,420,005 Effective search space: 98155961190 Effective search space used: 98155961190 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 126 (53.1 bits)