BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0435.0001.p (181 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_977532.1| transcriptional regulator, TetR family, putativ... 154 1e-36 ref|NP_834276.1| Transcriptional regulator, TetR family [Bacillu... 102 3e-21 ref|NP_980994.1| transcriptional regulator, TetR family [Bacillu... 101 7e-21 ref|NP_658599.1| tetR, Bacterial regulatory proteins, tetR famil... 101 8e-21 ref|NP_979438.1| transcriptional regulator, TetR family [Bacillu... 87 2e-16 >ref|NP_977532.1| transcriptional regulator, TetR family, putative [Bacillus cereus ATCC 10987] gb|AAS40140.1| transcriptional regulator, TetR family, putative [Bacillus cereus ATCC 10987] Length = 181 Score = 154 bits (388), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 67/180 (37%), Positives = 114/180 (63%) Query: 1 MMKVDRRVLKSQEAIKKAIIELMSEKSFDDITIRDISDRANVNRGTIYLHYMDKYDLLDK 60 M K+DRR++KSQ AI+ A IE++ FD+IT+++I+++AN+ R T YLHY+DKY+LLDK Sbjct: 1 MEKIDRRIIKSQNAIQSAFIEMLITDGFDEITVKNITEKANIGRKTFYLHYLDKYNLLDK 60 Query: 61 LIEEHISNLRELCHSASEMTFQEGNYVWFEYFAENHLFFTTMLNTKSAAYFRSRFLDLVV 120 ++++H+ L+E+C+ F EG +WFEYF E+ FF + + S F+ + L ++ Sbjct: 61 IVDDHLDQLKEICYEKQNKGFIEGTIIWFEYFKEHKPFFAALFKSNSTLSFQKKLLTFIM 120 Query: 121 QEYKPEVDVTEGKNQGLSEEVFLQFFGAAVVGAVEWWFRNGMLVPPRVMAEQTGILLDRN 180 E + +++ N+ + + + L+F G AV+G +E + N + +A Q G L+ RN Sbjct: 121 GEIEKKLNTNTSINKNIDKHIILKFLGTAVMGILESYVLNEIDSDVEYVATQVGELMRRN 180 >ref|NP_834276.1| Transcriptional regulator, TetR family [Bacillus cereus ATCC 14579] gb|AAP11477.1| Transcriptional regulator, TetR family [Bacillus cereus ATCC 14579] Length = 205 Score = 102 bits (255), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 55/179 (30%), Positives = 96/179 (53%), Gaps = 11/179 (6%) Query: 5 DRRVLKSQEAIKKAIIELMSEKSFDDITIRDISDRANVNRGTIYLHYMDKYDLLDKLIEE 64 D RV ++++ I+ A + L+ EK F+++T++ I++RA VNR T Y HY DKYDLLDK IEE Sbjct: 8 DPRVKRTRQLIQDAFVALVGEKGFENVTVQHIAERAPVNRATFYSHYHDKYDLLDKSIEE 67 Query: 65 HISNLRELCHSAS------EMTFQEGN---YVWFEYFAENHLFFTTMLNTKSAAYFRSRF 115 + L E+ + ++TF + FE+ AEN F+ ML K+A + + Sbjct: 68 MLEKLTEVIKPRNRNKEDFQLTFDSPHPSFLALFEHIAENTNFYNVMLGDKAAGNYTYKM 127 Query: 116 LDLVVQEYKPEVDVTEGKNQGL--SEEVFLQFFGAAVVGAVEWWFRNGMLVPPRVMAEQ 172 + + + +++ ++ L ++ + + A +G + W + GM+ P MA Q Sbjct: 128 MKAIQTHLTLSLSISQPNDEKLMVPRDILISYVTGAHLGMIMSWLKRGMIYTPHFMAMQ 186 >ref|NP_980994.1| transcriptional regulator, TetR family [Bacillus cereus ATCC 10987] gb|AAS43602.1| transcriptional regulator, TetR family [Bacillus cereus ATCC 10987] Length = 205 Score = 101 bits (252), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 54/179 (30%), Positives = 96/179 (53%), Gaps = 11/179 (6%) Query: 5 DRRVLKSQEAIKKAIIELMSEKSFDDITIRDISDRANVNRGTIYLHYMDKYDLLDKLIEE 64 D RV ++++ I+ A + L+ EK F+++T++ I++RA VNR T Y HY DKYDLLDK IEE Sbjct: 8 DPRVKRTRQLIQDAFVALVGEKGFENVTVQHIAERAPVNRATFYSHYHDKYDLLDKSIEE 67 Query: 65 HISNLRELCHSAS------EMTFQEGN---YVWFEYFAENHLFFTTMLNTKSAAYFRSRF 115 + L ++ + ++TF + FE+ AEN F+ ML K+A + + Sbjct: 68 MLEKLTKVIKQKNRNKEDFQLTFDSPHPSFLALFEHIAENANFYNVMLGDKAAGNYTYKM 127 Query: 116 LDLVVQEYKPEVDVTEGKNQGL--SEEVFLQFFGAAVVGAVEWWFRNGMLVPPRVMAEQ 172 + + + +++ ++ L ++ + + A +G + W + GM+ P MA Q Sbjct: 128 MKAIQTHLTLSLSISQPNDEKLMVPRDILISYVTGAHLGMIMSWLKKGMIYTPHFMAMQ 186 >ref|NP_658599.1| tetR, Bacterial regulatory proteins, tetR family [Bacillus anthracis A2012] ref|NP_847017.1| transcriptional regulator, TetR family [Bacillus anthracis str. Ames] gb|AAP28503.1| transcriptional regulator, TetR family [Bacillus anthracis str. Ames] Length = 205 Score = 101 bits (251), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 54/179 (30%), Positives = 95/179 (53%), Gaps = 11/179 (6%) Query: 5 DRRVLKSQEAIKKAIIELMSEKSFDDITIRDISDRANVNRGTIYLHYMDKYDLLDKLIEE 64 D RV ++++ I+ A + L+ EK F+++T++ I++RA VNR T Y HY DKYDLLDK IEE Sbjct: 8 DPRVKRTRQLIQDAFVALVGEKGFENVTVQHIAERAPVNRATFYSHYHDKYDLLDKSIEE 67 Query: 65 HISNLRELCHSAS------EMTFQEGN---YVWFEYFAENHLFFTTMLNTKSAAYFRSRF 115 + L E+ + ++ F + FE+ AEN F+ ML K+A + + Sbjct: 68 MLEKLTEVIKPKNRNKEDFQLAFDSPHPNFLALFEHIAENANFYNVMLGDKAAGNYTYKM 127 Query: 116 LDLVVQEYKPEVDVTEGKNQGL--SEEVFLQFFGAAVVGAVEWWFRNGMLVPPRVMAEQ 172 + + + +++ ++ L ++ + + A +G + W + GM+ P MA Q Sbjct: 128 MKAIQTHLTLSLSISQPNDEKLMVPRDILISYVTGAHLGMIMSWLKRGMIYTPHFMAMQ 186 >ref|NP_979438.1| transcriptional regulator, TetR family [Bacillus cereus ATCC 10987] gb|AAS42046.1| transcriptional regulator, TetR family [Bacillus cereus ATCC 10987] Length = 205 Score = 86.7 bits (213), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 53/185 (28%), Positives = 90/185 (48%), Gaps = 22/185 (11%) Query: 4 VDRRVLKSQEAIKKAIIELMSEKSFDDITIRDISDRANVNRGTIYLHYMDKYDLLDKLIE 63 +D RV++++ AI+ A +EL+ EK FD IT++DI+ +AN+NRGT Y HY DK+DL+ K E Sbjct: 6 LDLRVVRTKTAIRNAFVELIEEKGFDAITVKDITTKANINRGTFYAHYQDKFDLMTKCQE 65 Query: 64 EHISNLRELCH-------------SASEMTFQEGNYVWFEYFAENHLFFTTMLNTKSAAY 110 E + + + M F + E+ EN F +L+ K Sbjct: 66 EIMYKFSSIAKQKLPEVIADLGSSPSPTMPFIPITSI-LEFLNENSDFMKAVLSPKGDLS 124 Query: 111 FRSRFLDLVVQEYKPEVDVTEG-----KNQGLSEEVFLQFFGAAVVGAVEWWFRNGMLVP 165 F+++ D + +K + T G +N + + + +A +G ++ W NG Sbjct: 125 FQTKLKDFM---WKTIFEDTNGALINKENLLVPSQYLASYMASAHIGVIQQWLNNGQKET 181 Query: 166 PRVMA 170 P +A Sbjct: 182 PEEIA 186 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.323 0.137 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 253,332,281 Number of extensions: 9928888 Number of successful extensions: 29325 Number of sequences better than 1.0e-05: 89 Number of HSP's gapped: 29301 Number of HSP's successfully gapped: 90 Length of query: 181 Length of database: 757,237,578 Length adjustment: 118 Effective length of query: 63 Effective length of database: 436,855,896 Effective search space: 27521921448 Effective search space used: 27521921448 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 122 (51.6 bits)